CN203328838U - Device for manufacturing atrioventricular valve regurgitation animal model through atriums - Google Patents

Abstract

The utility model provides a device for making an animal model of atrioventricular valve regurgitation through the atrium, which includes a cutting rod (1) for cutting the valve and an outer sleeve (2) with a sealed communication tube, wherein: the belt is connected with a sealed tube The outer casing (2) of the pipe includes a connecting pipe (7) and a hollow metal pipe (8); the connecting pipe (7) and the hollow metal pipe (8) are sealed and communicated; the cutting rod (1) is installed on the hollow metal pipe In the rod (8); the utility model is simple and convenient to operate, easy to use, low in cost, easy to control the reverse flow rate, high in molding rate, and free of X-ray radiation risk. A device for making reflux animal disease models.

Description

Device for making animal models of atrioventricular valve regurgitation via transatrial route

technical field

The utility model relates to a device for making animal disease models, in particular to a device for making large animal atrioventricular valve regurgitation disease models. the

Background technique

Valvular regurgitation is a common clinical heart disease, among which mitral regurgitation (MR) is the most common in clinical practice, according to reports, ultrasonography mild MR can be as high as 19% in normal people, moderate MR Or severe MR was 1.9% and 0.2%, respectively. Mitral valve regurgitation increases the diastolic load of the left atrium and left ventricle, which can cause increased pulmonary venous and pulmonary capillary pressure, which in turn causes vasodilation and congestion; at the same time, the left ventricular diastolic volume load increases and the left ventricle expands. Severe mitral regurgitation can cause a sharp rise in the pressure of the left atrium and pulmonary veins, causing acute pulmonary edema. Chronic MR is also harmful. If it is not diagnosed and treated in time, atrial fibrillation will easily occur, and it often leads to left heart failure such as pulmonary congestion and hypoperfusion of the systemic circulation. In the late stage, pulmonary hypertension and whole heart failure may occur, which directly threaten life. Because of this, the clinical importance of MR has been paid more and more attention. Research on the mechanism, pathophysiological characteristics and new technologies of diagnosis and treatment of MR has been carried out extensively. Some new imaging diagnostic techniques, especially the development and changes of atrial fibrillation Research hotspots in fields such as the mechanism of heart failure, the evaluation of medical and surgical treatment methods for heart failure all require a good and stable large animal model of MR. the

At present, the establishment of such animal models mainly affects the tight closure of the valve by destroying, changing or affecting the main structures of the mitral valve device such as valve leaflets, chordae, papillary muscles, valve ring, left atrium or left ventricle, thereby causing blood flow from the ventricle. Regurgitation to the atrium to achieve the purpose of making a large animal model of atrioventricular valve regurgitation. Among them, it is most easily achieved by injuring the valve leaflets and chordae. There are two ways to make animal valvular regurgitation models by this method: opening the chest and not opening the chest. The traditional thoracotomy method of making mitral valve regurgitation models generally needs to use extracorporeal circulation to cut off the damaged valve or chordae through the left atrial appendage under direct vision. The models made by this method are relatively uniform and accurate, but the cost is relatively high. The trauma is relatively large; there is also a model-making method in which the mitral valve is damaged by jumping off the apex of the heart continuously. This method is also technically difficult and the trauma is still relatively large. The non-thoracotomy method mainly refers to the use of catheter intervention technology under the guidance of X-rays to destroy the valve or chordae with special graspers. This method generally requires the use of ultrasound to determine the size of the regurgitation. The lower operation requires relatively high technical requirements, great difficulty, and high cost. The controllability of the long-distance operation model is also relatively poor. Often, the strain is too severe and the mortality rate is high, or the strain is light, the model is not uniform enough, and the operation is relatively difficult. It is cumbersome, the model is poorly reproducible, repeated injections of contrast agents are often required, the consumables are expensive, and the model makers need to be exposed to X-rays, which limits the practical application of this method, and the establishment of mitral regurgitation models was once stuck in a bottleneck stage. the

From the above, the existing atrioventricular valve regurgitation animal disease modeling technology has the following deficiencies: the trauma of traditional surgical operations is large, the animals are susceptible to infection, the mortality rate of animals is high, and the cost is high; The method requires special modeling tools, cumbersome operation, high technical difficulty, difficult to grasp the size of reflux flow, poor reproducibility of model making, high mortality rate, poor model uniformity, frequent injection of contrast agent, expensive consumables, difficult for model makers and animals All need to be exposed to high-dose X-ray radiation, which makes its use limited. the

Utility model content

In order to overcome the above-mentioned technical problems, the purpose of this utility model is aimed at the urgent need of the atrioventricular valve regurgitation animal disease model at present, the trauma of the traditional disease model surgical preparation method is large, prone to infection, the animal mortality rate is high, and the shortcomings of high cost, Provided is a device for making an animal model of atrioventricular valve regurgitation via atrial route. the

In order to achieve the above object, a device for making an animal model of atrioventricular valve regurgitation through the atrium described in the utility model includes a cutting rod for cutting the valve and an outer sleeve with a sealed connecting tube, wherein:

The outer casing with a sealed connecting pipe includes a connecting pipe and a hollow metal pipe;

The connecting pipe is in sealed communication with the hollow metal pipe;

The cutting rod is matched and installed in the hollow metal tube. the

The cutting rod includes a metal rod and a cutting barb connected to the bottom end of the metal rod. the

The cutting rod also includes a hand-held kit, which is fixedly connected to the other end of the metal rod. the

The outer casing with the sealing connecting pipe also includes a sealing head; wherein:

The sealing head is provided with a sealing round hole and a side sealing connection hole;

The hollow metal tube is sealed and connected with the sealing round hole;

The communication pipe is sealingly connected with the side seal connecting hole. the

The outer casing with a sealed communication pipe also includes a valve, which is sealed and connected with the other end of the communication pipe. the

The advantage of the atrioventricular valve regurgitation animal model making device through the atrium approach described in the utility model is:

1. Using a small incision transatrial ventricular valve regurgitation animal model making device to make animal atrioventricular valve regurgitation models is simple to operate, easy to use, and can achieve minimally invasive small incisions, without stopping the heart, without extracorporeal circulation, and semi-quantitative control of the reflux flow , can accurately locate the leaflet to be destroyed, and the modeling rate is high. the

2. Using the valve cutting device to make animal valve regurgitation models does not require X-ray imaging, has no risk of X-ray radiation, is low in cost, easy to promote, and can be widely used. the

Description of drawings

Fig. 1 is a front view of an embodiment of the utility model. the

Fig. 2 is a front view of the cutting rod in an embodiment of the utility model. the

Fig. 3 is a front view of an outer casing with a sealed communication pipe in an embodiment of the present invention. the

Detailed ways

Embodiment of the utility model is described below with reference to accompanying drawing. Elements and features described in one drawing or one embodiment of the present invention may be combined with elements and features shown in one or more other drawings or embodiments. It should be noted that, for the purpose of clarity, representation and description of components or processes that are not relevant to the present invention and known to those of ordinary skill in the art are omitted in the drawings and descriptions. the

Below in conjunction with accompanying drawing, the utility model is further described. the

Fig. 1 is a front view of an embodiment of the utility model, as shown in Fig. 1, a kind of atrioventricular valve regurgitation animal model making device through the atrium approach described in the utility model, comprises the cutting bar for cutting valve 1 and an outer sleeve 2 with a sealed communication tube, wherein: the outer sleeve 2 with a sealed communication tube includes a communication tube 7 and a hollow metal tube 8; the communication tube 7 and the hollow metal tube 8 are in sealed communication. the

Fig. 2 is a front view of the cutting rod in an embodiment of the utility model, as shown in Fig. 2, the cutting rod 1 comprises a metal rod 4, a cutting barb 5, and a hand-held kit 3, and one end of the metal rod 4 is provided with a cutting The barb 5 and the hand-held kit 3 are fixedly connected to the other end of the metal rod 4 . Wherein, the hand-held kit 3 is made of plastic material, with textures for easy gripping or holding; the metal rod 4 is made of high-strength stainless metal, and its diameter is not larger than that of the outer sleeve 2 with a sealed communication tube. The inner diameter is preferably 3 mm; the length is slightly longer than the outer casing 2 with a sealed communication pipe, preferably 20 cm; the cutting barb 5 is in the shape of an "L" hook knife, and its cross section does not exceed the cross section of the metal rod. the

Fig. 3 is a front view of an outer casing with a sealing connecting pipe in an embodiment of the present invention. As shown in Fig. 3, the outer casing 2 with a sealing connecting pipe includes a sealing head 6, a connecting pipe 7, a hollow metal Pipe 8, three-way valve 11; wherein: the sealing head 6 is provided with a sealing round hole 9 and a side sealing connection hole 10; the hollow metal pipe 8 is in sealing connection with the sealing round hole 9; Sealed connection; the three-way valve 11 is sealed with the other end of the communicating pipe 7. the

Wherein, the sealing head 6 is made of a low cylindrical hollow plastic material, the center of the sealing hole 9 is on the same line as the center of the cross section of the hollow metal tube 8, and the diameter of the sealing hole 9 is smaller than that of the hollow metal tube. The tube 8 is the same, the hollow metal tube 8 is made of strength stainless hollow metal, the diameter is larger than the metal rod 4, the preferred inner diameter is 3.5 mm, the preferred outer diameter is 4 mm, the length is smaller than the metal rod 4, and the preferred diameter is 15 cm; The communication pipe 7 described above is made of a plastic hollow hose, one end is connected to the sealing head 6, and the other end is connected to the three-way valve 11. the

The use process of the transatrial approach atrioventricular valve regurgitation animal model making device described in the utility model is:

Before use, the animal to be modeled should be routinely anesthetized, tracheal intubated, and intravenous access established. If the left atrioventricular valve regurgitation model is established, the animal should be placed in the right lateral position. Happy bag, sew a purse on the left atrial appendage, insert the pre-sewn purse through the outer cannula 2 with a sealed connecting tube into the left atrial appendage, enter the left atrium, continue to penetrate the mitral valve, and then pass through the connecting tube 7 Determine whether the hollow metal tube 8 enters the ventricle by the speed of the outflowing blood. After the hollow metal tube 8 enters and passes through the mitral valve, take out the cutting rod 1 and insert it through the sealing round hole 9 of the sealing head 6 and pass through the hollow metal tube 8 After the cutting barb 5 protrudes from the hollow metal tube 8, you can try to withdraw it. When you feel that the cutting barb 5 is hanging on the valve tissue, you can withdraw the cutting rod 1 with a little force. At this time, you can cut off the valve. After the modeling operation is completed, other atrioventricular valve regurgitation animal disease models can be made by referring to the mitral valve regurgitation animal disease model production method, and the success of the modeling can be observed in real time with the help of ultrasound machines and other equipment. the

The utility model is simple and convenient in operation, easy to use, low in cost, easy to control the reflux flow, high in molding rate, and free from X-ray radiation risk. device. the

Although the present invention and its advantages have been described in detail, it should be understood that various changes, substitutions and alterations can be made without departing from the spirit and scope of the invention as defined by the appended claims. Moreover, the scope of the present application is not limited to the specific embodiments of the procedures, devices, means, methods and steps described in the specification. Those of ordinary skill in the art will readily understand from the disclosure of the utility model that, according to the utility model, it is possible to use existing and existing products that perform substantially the same functions or obtain substantially the same results as the corresponding embodiments described herein. A process, device, means, method or procedure to be developed in the future. Accordingly, the appended claims are intended to include within their scope such processes, means, means, methods or steps. the

Claims (5)

1. one kind through the anti-fluid modelling of atrium approach chamber valve device, it is characterized in that: comprise cutter bar (1) and the trocar sheath (2) of band sealing communicating pipe for cutting valve, wherein:

The trocar sheath (2) of described band sealing communicating pipe comprises communicating pipe (7) and hollow metal pipe (8);

Described communicating pipe (7) and hollow metal pipe (8) sealing are communicated with;

Described cutter bar (1) is supporting to be arranged in hollow metal pipe (8).

2. according to claim 1 through the anti-fluid modelling of atrium approach chamber valve device, it is characterized in that: described cutter bar (1) comprises the cutting barb (5) that metallic rod (4) is connected with metallic rod (4) bottom.

3. according to claim 1 and 2 through the anti-fluid modelling of atrium approach chamber valve device, it is characterized in that: described cutter bar (1) also comprises hand-held external member (3), and hand-held external member (3) is fixedly connected on the other end of metallic rod (4).

4. according to claim 1 through the anti-fluid modelling of atrium approach chamber valve device, it is characterized in that: the trocar sheath (2) of described band sealing communicating pipe also comprises seal header joints (6); Wherein:

Described seal header joints (6) is provided with sealing circular hole (9) and side seal connecting hole (10);

Described hollow metal pipe (8) is tightly connected with sealing circular hole (9);

Described communicating pipe (7) is tightly connected with side seal connecting hole (10).

5. described through the anti-fluid modelling of atrium approach chamber valve device according to claim 1 or 4, it is characterized in that: the trocar sheath (2) of described band sealing communicating pipe also comprises valve (11), and valve (11) is tightly connected with the other end of communicating pipe (7).

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