CN203107699U - Sodium bicarbonate injection flexible package - Google Patents
Sodium bicarbonate injection flexible package Download PDFInfo
- Publication number
- CN203107699U CN203107699U CN 201320056699 CN201320056699U CN203107699U CN 203107699 U CN203107699 U CN 203107699U CN 201320056699 CN201320056699 CN 201320056699 CN 201320056699 U CN201320056699 U CN 201320056699U CN 203107699 U CN203107699 U CN 203107699U
- Authority
- CN
- China
- Prior art keywords
- sodium bicarbonate
- bicarbonate injection
- flexible package
- package
- barrier layer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 title claims abstract description 178
- 229910000030 sodium bicarbonate Inorganic materials 0.000 title claims abstract description 89
- 235000017557 sodium bicarbonate Nutrition 0.000 title claims abstract description 89
- 238000002347 injection Methods 0.000 title claims abstract description 77
- 239000007924 injection Substances 0.000 title claims abstract description 77
- 239000004743 Polypropylene Substances 0.000 claims abstract description 45
- 229920001155 polypropylene Polymers 0.000 claims abstract description 44
- -1 polypropylene Polymers 0.000 claims abstract description 42
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims abstract description 30
- 239000001569 carbon dioxide Substances 0.000 claims abstract description 15
- 229910002092 carbon dioxide Inorganic materials 0.000 claims abstract description 15
- 238000013461 design Methods 0.000 claims abstract description 10
- 238000007789 sealing Methods 0.000 claims abstract description 10
- 230000004888 barrier function Effects 0.000 claims description 24
- 238000012946 outsourcing Methods 0.000 claims description 19
- 239000011324 bead Substances 0.000 claims description 10
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 6
- 238000005538 encapsulation Methods 0.000 claims description 4
- 239000005030 aluminium foil Substances 0.000 claims description 3
- 239000000377 silicon dioxide Substances 0.000 claims description 3
- 235000012239 silicon dioxide Nutrition 0.000 claims description 3
- 238000000354 decomposition reaction Methods 0.000 abstract description 2
- 238000009792 diffusion process Methods 0.000 description 7
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 6
- 238000000151 deposition Methods 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 230000008569 process Effects 0.000 description 5
- 238000003860 storage Methods 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 229910001868 water Inorganic materials 0.000 description 4
- 239000007864 aqueous solution Substances 0.000 description 3
- 230000003139 buffering effect Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 239000012528 membrane Substances 0.000 description 3
- 238000004321 preservation Methods 0.000 description 3
- 229910000029 sodium carbonate Inorganic materials 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000002253 acid Substances 0.000 description 2
- 239000000872 buffer Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- 238000013467 fragmentation Methods 0.000 description 2
- 238000006062 fragmentation reaction Methods 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- VUZPPFZMUPKLLV-UHFFFAOYSA-N methane;hydrate Chemical compound C.O VUZPPFZMUPKLLV-UHFFFAOYSA-N 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 208000010444 Acidosis Diseases 0.000 description 1
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical class [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 1
- 241001411320 Eriogonum inflatum Species 0.000 description 1
- 206010020601 Hyperchlorhydria Diseases 0.000 description 1
- 206010027417 Metabolic acidosis Diseases 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- 229940069428 antacid Drugs 0.000 description 1
- 239000003159 antacid agent Substances 0.000 description 1
- 230000001458 anti-acid effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000011169 microbiological contamination Methods 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 229920005992 thermoplastic resin Polymers 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Images
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- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
The utility model discloses a sodium bicarbonate injection flexible package which comprises a polypropylene flexible package body used for containing sodium bicarbonate injection. The polypropylene flexible package body is designed to be of a double-layer structure. The polypropylene flexible package body comprises an inner package and an outer package, wherein the inner package is used for containing the sodium bicarbonate injection, and the outer package is provided with a gas-barrier layer. The inner package is filled with carbon dioxide gas. The inner package is a multilayer-film inner package. The inner package is provided with a gas-barrier layer. The edge of the inner package and the edge of the outer package forms an edge-sealing layer in a heat-sealing mode, wherein the width of the edge-sealing layer is 0.2cm to 0.4cm. According to the structure, the polypropylene flexible package body has higher toughness and good mechanical properties, and the sodium bicarbonate injection flexible package can not be damaged under the condition that the sodium bicarbonate injection flexible package bears large pressure or impact or collision. Due to the facts that the double-layer design is adopted on the polypropylene flexible package body, and the carbon dioxide gas is filled into the inner package, the problem of decomposition of the sodium bicarbonate injection is solved, and the quality of the sodium bicarbonate injection is ensured.
Description
Technical field
This utility model relates to technical field of medicine packaging, more particularly, and particularly a kind of sodium bicarbonate injection flexible package.
Background technology
Sodium bicarbonate (Sodium Bicarbonate) is commonly called as " sodium bicarbonate ", is white fine crystals, and the dissolubility in water is less than sodium carbonate.Sodium bicarbonate solid decomposes generation sodium carbonate, carbon dioxide and water gradually in beginning more than 50 ℃, decomposes fully in the time of 270 ℃.Sodium bicarbonate is in highly basic and the weak acid and the acid salt of back generation, presents alkalescence when water-soluble.
In medical field, sodium bicarbonate injection is usually used in treating metabolic acidosis, alkalized urine, as antacid, the symptom that the treatment hyperchlorhydria causes etc.Be alkalescence behind the molten water of sodium bicarbonate, easily be decomposed into sodium carbonate, carbon dioxide and water in storage process, if the sodium bicarbonate in the aqueous solution decomposes, its pH value then can change, if after being expelled to human body, then can cause the disorder of pH value in the human body body.
The branch of sodium bicarbonate aqueous solution solve an equation into:
By following formula as can be known, sodium bicarbonate aqueous solution be decomposed into reversible balancing response process, so prevent that one of approach that sodium bicarbonate decomposes is exactly to guarantee that the carbon dioxide that sodium bicarbonate injection decomposites does not run off.Because vial has higher gas barrier property, so in the prior art,, use vial that sodium bicarbonate injection is sealed up for safekeeping, to avoid the loss of carbon dioxide (carbon dioxide that is decomposited by sodium bicarbonate injection) in storage process.
Use vial that sodium bicarbonate is sealed up for safekeeping, though can guarantee to avoid the diffusion of carbon dioxide,, because sodium bicarbonate solution is alkalescent medicine, contact with vial for a long time, chemical reaction very easily takes place, cause product visible foreign matters index in storage process defective; The sodium bicarbonate product that vial is sealed up for safekeeping bottle stopper when high temperature sterilize is very easily washed open, causes poorly sealedly, causes that the product P H-number is unusual, microbiological contamination etc.In addition because the manufacturing cost of vial is higher, and bottle is cracked easily, and also depositing of sodium bicarbonate injection proposed higher requirement (avoiding vial that the situation of fragmentation takes place owing to reasons such as collisions).
In sum, how to reduce sodium bicarbonate injection in the decomposition of producing and depositing in the process, become those skilled in the art's problem demanding prompt solution.
The utility model content
The technical problems to be solved in the utility model is for providing a kind of sodium bicarbonate injection flexible package, the soft employing polypropylene of this sodium bicarbonate injection Soft Roll splendid attire sodium bicarbonate injection, by its structural design, can solve the resolution problem of sodium bicarbonate injection in producing and depositing.
For solving the problems of the technologies described above, this utility model provides a kind of sodium bicarbonate injection flexible package, is used for the encapsulation of sodium bicarbonate injection,
Comprise the polypropylene Soft Roll for the splendid attire sodium bicarbonate injection;
Described polypropylene Soft Roll designs for double-decker;
Described polypropylene Soft Roll comprises for the interior bag of splendid attire sodium bicarbonate injection and the outsourcing that is provided with gas barrier layer;
Be filled with carbon dioxide in the bag in described;
Described interior bag is bag in the multilayer film, and described interior bag has gas barrier layer;
Bag is formed with the wide bead layer of 0.2cm to 0.4cm with the edge of described outsourcing by heat-sealing in described.
Preferably, described gas barrier layer is the silicon dioxide gas barrier layer.
Preferably, described gas barrier layer is the aluminium foil gas barrier layer.
Preferably, described polypropylene soft is wrapped and is provided with the Medical combined cover that is communicated with described interior bag.
This utility model provides a kind of sodium bicarbonate injection flexible package, is used for the encapsulation of sodium bicarbonate injection, comprises the polypropylene Soft Roll for the splendid attire sodium bicarbonate injection; The polypropylene Soft Roll designs for double-decker; The polypropylene Soft Roll comprises for the interior bag of splendid attire sodium bicarbonate injection and the outsourcing that is provided with gas barrier layer; Be filled with carbon dioxide in the interior bag; Interior bag is bag in the multilayer film, and interior bag has gas barrier layer; Interior bag is formed with the wide bead layer of 0.2cm to 0.4cm with the edge of outsourcing by heat-sealing.
Use polypropylene to be made into the polypropylene Soft Roll, can make the polypropylene Soft Roll have high toughness and excellent mechanical property, than vial, the sodium bicarbonate injection flexible package can be born bigger pressure or impact and is not damaged, thus the carrying that reduces sodium bicarbonate injection dramatically with deposit requirement.
Be provided with bead layer, the sealing property of bead layer is better, therefore can make to the utlity model has higher air-tightness, thereby guarantee product quality.
The sodium bicarbonate injection flexible package that this utility model provides owing to adopt the polypropylene Soft Roll that sodium bicarbonate injection is packed preservation, can reduce the requirement of depositing of sodium bicarbonate injection.Simultaneously, the polypropylene Soft Roll adopts double layer design, with the mark off insulating space of sodium bicarbonate injection to extraneous transition strictness, for preventing that the sodium bicarbonate injection degraded from providing buffer condition, the environmental structure that can also effectively keep insulating space, guarantee the stability of insulating space, thereby more effectively consolidated the degraded buffering of sodium bicarbonate injection.Be provided with gas barrier layer at Nei Bao, the gas diffusion in can avoiding in the bag.Simultaneously, filling arbon dioxide gas in the interior bag then can reach and suppress the purpose that sodium bicarbonate injection decomposes, and has guaranteed the product quality of sodium bicarbonate injection.Simultaneously, the edge of Nei Bao and described outsourcing has bead layer, can improve the air-tightness of polypropylene Soft Roll, prevents the gas diffusion.And this novel flexible package as a globality is different from the common double packing for sodium bicarbonate injection, has more convenient production use and clinical practice.
Description of drawings
In order to be illustrated more clearly in this utility model embodiment or technical scheme of the prior art, to do to introduce simply to the accompanying drawing of required use in embodiment or the description of the Prior Art below, apparently, accompanying drawing in describing below only is embodiment of the present utility model, for those of ordinary skills, under the prerequisite of not paying creative work, can also obtain other accompanying drawing according to the accompanying drawing that provides.
Fig. 1 is the structural representation of sodium bicarbonate injection flexible package among a kind of embodiment of this utility model;
The corresponding relation of component names and Reference numeral is among Fig. 1:
Polypropylene Soft Roll 1; Interior bag 11; Outsourcing 12; Bead layer 2.
The specific embodiment
Core of the present utility model is for providing a kind of sodium bicarbonate injection flexible package, and the soft employing polypropylene of this sodium bicarbonate injection Soft Roll splendid attire sodium bicarbonate injection by its structural design, has solved the resolution problem of sodium bicarbonate injection in producing and depositing.
In order to make those skilled in the art understand the technical solution of the utility model better, the utility model is described in further detail below in conjunction with the drawings and specific embodiments.
Please refer to Fig. 1, Fig. 1 is the structural representation of sodium bicarbonate injection flexible package among a kind of embodiment of this utility model.
This utility model provides a kind of sodium bicarbonate injection flexible package, is used for the encapsulation of sodium bicarbonate injection.The available technology adopting vial is packed preservation to sodium bicarbonate injection.Yet, because the vial quality is more crisp, cause its bearing capacity lower, and cracked easily when being subjected to hard thing bump.In order to solve the vial problem of fragmentation easily, the utility model proposes following technical scheme: the sodium bicarbonate injection flexible package comprises the polypropylene Soft Roll 1 for the splendid attire sodium bicarbonate injection; Polypropylene Soft Roll 1 designs for double-decker; Polypropylene Soft Roll 1 comprises for the interior bag 11 of splendid attire sodium bicarbonate injection and the outsourcing 12 that is provided with gas barrier layer; Be filled with carbon dioxide in the interior bag 11; Bag 11 is bag in the multilayer film in described, and interior bag 11 has gas barrier layer; Interior bag 11 is formed with the wide bead layer of 0.2cm to 0.4cm 2 with the edge of outsourcing 12 by heat-sealing.
In this utility model, the double-decker design is adopted in the sodium bicarbonate injection flexible package, can improve the safety of sodium bicarbonate injection packing, provide the buffering insulating space for preventing the sodium bicarbonate injection degraded, reduce storage and the movement requirement of sodium bicarbonate injection dramatically.
Polypropylene, English name: Polypropylene(PP), be a kind of thermoplastic resin that is made by propylene polymerization, it has the characteristics of compound with regular structure, highly crystallineization, and fusing point can be up to 167 ℃.Polypropylene is heat-resisting, corrosion-resistant, have excellent mechanical property, and the sterilization of goods used vapour is its outstanding advantage.Density is little, is the lightest general-purpose plastics.
Use polypropylene to be made into polypropylene Soft Roll 1, can make polypropylene Soft Roll 1 have high toughness and excellent mechanical property, than vial, the sodium bicarbonate injection flexible package can be born bigger pressure or impact and is not damaged, thus the carrying that reduces sodium bicarbonate injection dramatically with deposit requirement.
The concrete making step of polypropylene Soft Roll is:
1, adopts polypropylene material to make the polypropylene Soft Roll, and be arranged to double-decker; Heat-sealing forms the wide bead layer of 0.2cm to 0.4cm, reaches the effect that prevents gas leakage.
2, internally carry out vacuum pumping between bag and the outsourcing;
After above-mentioned steps 2, can also increase step 21: filling arbon dioxide gas between outsourcing 12 and interior bag 11, diffusion, carbon dioxide in can impelling in the bag 11 reaches vapor liquid equilibrium, thereby the content of carbon dioxide in the bag 11 in still can guaranteeing reaches and suppresses the purpose that sodium bicarbonate injection decomposes.
Above-mentioned steps is carried out the sodium bicarbonate injection fill after finishing, and the steps include:
3, fill sodium bicarbonate injection in the inside bag;
4, filling arbon dioxide gas in the inside bag;
5, the polypropylene Soft Roll is carried out sealing operation.
The sodium bicarbonate injection flexible package that this utility model provides owing to adopt 1 pair of sodium bicarbonate injection of polypropylene Soft Roll to pack preservation, can reduce the requirement of depositing of sodium bicarbonate injection.Simultaneously, polypropylene Soft Roll 1 adopts double layer design, with the mark off insulating space of sodium bicarbonate injection to extraneous transition strictness, for preventing that the sodium bicarbonate injection degraded from providing buffer condition, the environmental structure that can also effectively keep insulating space, guarantee the stability of insulating space, thereby more effectively consolidated the degraded buffering of sodium bicarbonate injection.
Particularly, outsourcing 12 is provided with gas barrier layer, and gas barrier layer can be arranged at the inboard of outsourcing 12, also can be arranged at the intermediate layer of multilayer film when multi-layer film structure is adopted in outsourcing 12.When this need illustrate, when multilayer film was adopted in outsourcing 12, it was basal layer with the polypropylene screen, arranged then to have the functional membrane of choke effect, and then on the functional membrane one deck polypropylene screen had been set, and trilamellar membrane forms multilayer film by compacting.
In a specific embodiment of the present utility model, gas barrier layer is the silicon dioxide gas barrier layer.
In a specific embodiment of the present utility model, for the ease of patient is infused, polypropylene Soft Roll 1 is provided with the Medical combined cover that is communicated with interior bag 11.The composite cover structure that provides in the prior art is provided Medical combined cover, and it is communicated with interior bag 11, and specific implementation is: can arrange with outsourcing 12 on, the employing conduit is communicated with interior bag 11; Also can directly be communicated with interior bag 11, be packaged in then in the outsourcing 12.
In another specific embodiment of the present utility model, gas barrier layer is the aluminium foil gas barrier layer.
More than a kind of sodium bicarbonate injection flexible package provided by the utility model is described in detail.Used specific case herein principle of the present utility model and embodiment are set forth, the explanation of above embodiment just is used for helping to understand method of the present utility model and core concept thereof.Should be understood that; for those skilled in the art; under the prerequisite that does not break away from this utility model principle, can also carry out some improvement and modification to this utility model, these improvement and modification also fall in the protection domain of this utility model claim.
Claims (4)
1. sodium bicarbonate injection flexible package is used for the encapsulation of sodium bicarbonate injection, it is characterized in that,
Comprise the polypropylene Soft Roll (1) for the splendid attire sodium bicarbonate injection;
Described polypropylene Soft Roll (1) designs for double-decker;
Described polypropylene Soft Roll (1) comprises for the interior bag (11) of splendid attire sodium bicarbonate injection and the outsourcing (12) that is provided with gas barrier layer;
Be filled with carbon dioxide in the bag (11) in described;
Bag (11) is formed with the wide bead layer of 0.2cm to 0.4cm (2) with the edge of described outsourcing (12) by heat-sealing in described;
Bag (11) is bag in the multilayer film in described, and described interior bag has gas barrier layer.
2. sodium bicarbonate injection flexible package according to claim 1 is characterized in that, described gas barrier layer is the silicon dioxide gas barrier layer.
3. sodium bicarbonate injection flexible package according to claim 1 is characterized in that, described gas barrier layer is the aluminium foil gas barrier layer.
4. according to each described sodium bicarbonate injection flexible package of claim 1 to 3, it is characterized in that described polypropylene Soft Roll (1) is provided with the Medical combined cover that is communicated with described interior bag (11).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320056699 CN203107699U (en) | 2013-01-31 | 2013-01-31 | Sodium bicarbonate injection flexible package |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201320056699 CN203107699U (en) | 2013-01-31 | 2013-01-31 | Sodium bicarbonate injection flexible package |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203107699U true CN203107699U (en) | 2013-08-07 |
Family
ID=48888083
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201320056699 Expired - Lifetime CN203107699U (en) | 2013-01-31 | 2013-01-31 | Sodium bicarbonate injection flexible package |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203107699U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104107140A (en) * | 2014-06-23 | 2014-10-22 | 武汉药谷生物工程有限公司 | Flexible package for injections including sodium bicarbonate |
| US11925703B1 (en) | 2022-07-29 | 2024-03-12 | Xellia Pharmaceuticals Aps | Liquid composition comprising glucose |
-
2013
- 2013-01-31 CN CN 201320056699 patent/CN203107699U/en not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104107140A (en) * | 2014-06-23 | 2014-10-22 | 武汉药谷生物工程有限公司 | Flexible package for injections including sodium bicarbonate |
| US11925703B1 (en) | 2022-07-29 | 2024-03-12 | Xellia Pharmaceuticals Aps | Liquid composition comprising glucose |
| US12178903B1 (en) | 2022-07-29 | 2024-12-31 | Hikma Pharmaceuticals Usa Inc. | Liquid composition comprising glucose |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20130807 |