CN201996544U - Minimally invasive and continuous type monitoring sensor for glucose - Google Patents
Minimally invasive and continuous type monitoring sensor for glucose Download PDFInfo
- Publication number
- CN201996544U CN201996544U CN2010206066974U CN201020606697U CN201996544U CN 201996544 U CN201996544 U CN 201996544U CN 2010206066974 U CN2010206066974 U CN 2010206066974U CN 201020606697 U CN201020606697 U CN 201020606697U CN 201996544 U CN201996544 U CN 201996544U
- Authority
- CN
- China
- Prior art keywords
- electrode
- glucose
- pedestal
- needle
- plug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title claims abstract description 26
- 239000008103 glucose Substances 0.000 title claims abstract description 26
- 238000012544 monitoring process Methods 0.000 title claims abstract description 16
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims abstract description 17
- 108090000790 Enzymes Proteins 0.000 claims abstract description 10
- 102000004190 Enzymes Human genes 0.000 claims abstract description 10
- 239000000853 adhesive Substances 0.000 claims description 16
- 230000001070 adhesive effect Effects 0.000 claims description 16
- 239000012528 membrane Substances 0.000 claims description 4
- 238000005516 engineering process Methods 0.000 abstract description 7
- 229940088598 enzyme Drugs 0.000 description 7
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 206010033675 panniculitis Diseases 0.000 description 4
- 210000004304 subcutaneous tissue Anatomy 0.000 description 4
- 108010015776 Glucose oxidase Proteins 0.000 description 2
- 239000004366 Glucose oxidase Substances 0.000 description 2
- 238000002848 electrochemical method Methods 0.000 description 2
- 210000003722 extracellular fluid Anatomy 0.000 description 2
- 229940116332 glucose oxidase Drugs 0.000 description 2
- 235000019420 glucose oxidase Nutrition 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 108010050375 Glucose 1-Dehydrogenase Proteins 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 238000011895 specific detection Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Images
Landscapes
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model relates to a minimally invasive and continuous type monitoring sensor for glucose. The sensor comprises an acicular reference electrode and at least an acicular working electrode which comprises a conducting layer and an enzyme film layer, and is characterized in that the sensor also comprises a pedestal, a plug and an adherence member; the acicular reference electrode and the working electrode are arranged at one side of the pedestal and the plug is disposed at the other side of the pedestal; terminals of the plug are connected with the acicular electrode; and the adherence member is arranged at one side of the pedestal, and is arranged at the same side with the acicular electrode. The utility model has the advantages of reasonable structure and practicality. A minimally invasive electrochemical enzyme electrode monitoring technology is employed and a glucose electrochemical testing technology is high in accuracy, so that glucose data for each minute of the coming three to four days can be continuously provided and a continuous glucose monitoring is truly realized.
Description
Technical field
This utility model relates to technical field of medical instruments, particularly is used for the pick off of glucose level continuous monitoring.
Background technology
According to WHO(World Health Organization (WHO)) number of diabetics increases sharply in the statistics global range, and diabetes have become the chronic disease of the 3rd serious harm human health after tumor, cardiovascular and cerebrovascular disease in the world.In the prior art, can adopt two kinds of sample modes of wound and no wound to detect patient's blood glucose value.
No. 200910097842.2 applications for a patent for invention of China disclose a kind of needle amperometric determination type glucose sensor for subcutaneous tissue real-time monitoring, comprise a needle-like formula reference electrode and at least one needle-like formula working electrode, working electrode comprises conductive layer and enzyme membrane layer.Above-mentioned prior art main innovate point is the structure and the function of needle-like formula electrode itself, do not provide the preferred application mode of needle-like formula electrode as pick off principal organ, promptly do not provide a kind of by needle-like formula electrode and miscellaneous part constitute rational in infrastructure, be suitable for practical sensor construction.
Summary of the invention
This utility model is based on the needle-like formula electrode of Wicresoft, but provide a kind of continuous monitoring glucose level and rational in infrastructure, be suitable for practical glucose monitoring pick off.
This utility model purpose can be realized by following technical scheme: a kind of Wicresoft continuous glucose monitoring pick off, comprise a needle-like formula reference electrode and at least one needle-like formula working electrode, and working electrode comprises conductive layer and enzyme membrane layer; It is characterized in that: also comprise pedestal, plug and adhesive, needle-like formula reference electrode and working electrode are arranged on pedestal one side, and plug is arranged on the pedestal opposite side, and the terminal of plug is connected with needle-like formula electrode, adhesive is arranged on pedestal one side, is positioned at homonymy with needle-like formula electrode.
Also comprise the adhesive cover layer, be used to cover the adhesive face of adhesive 14 or be torn in use.
Advantage of the present utility model: rational in infrastructure, be suitable for practicality, what adopt is Wicresoft's electrochemical enzyme electrode monitoring technology, glucose Electrochemical Measurement Technology accuracy rate height can provide the glucose data of per minute in following 3-4 days continuously, really realizes continuous glucose monitoring.
Description of drawings
The front schematic view of the pick off that Fig. 1 provides for embodiment.
The side schematic view of the pick off that Fig. 2 provides for embodiment.
The specific embodiment
In conjunction with Figure 1 and Figure 2, the pick off that adopts in the present embodiment comprises plug 11, pedestal 12, needle-like formula electrode 13 and adhesive 14 and adhesive cover layer 15.Needle-like formula electrode 13 comprises a reference electrode and at least one working electrode (being two working electrodes shown in Fig. 2), each working electrode is made of conductive layer and enzyme membrane layer (glucoseoxidase or glucose dehydrogenase that can the specific detection glucose be used for detecting the concentration of glucose in the subcutaneous tissue liquid).Needle-like formula electrode 13 is arranged on pedestal 12 1 sides, plug 11 is arranged on pedestal 12 opposite sides, and the terminal of plug 11 is connected with needle-like formula electrode 13, and adhesive 14 is arranged on pedestal 12 1 sides, be positioned at homonymy with needle-like formula electrode, the adhesive face of adhesive 14 covers (when not using) by cover layer 15.
During use, the cover layer 15 of tearing, pedestal 12 is sticked at skin surface by adhesive 14, needle-like formula electrode 13 is implanted in the subcutaneous tissue, contact with the subcutaneous tissue interstitial fluid, the micro-glucose molecule in the interstitial fluid contacts with the glucoseoxidase of needle-like formula electrode surface and reacts, and produces the signal of telecommunication, the signal of telecommunication is received and is delivered to data acquisition unit by electrode, realize the glucose detection function.The plug 11 that is provided with is used for being connected with data acquisition unit with power supply on the other hand, thereby for pick off provides work energy, the detected glucose information of while pick-up transducers.
What this utility model adopted is Wicresoft's electrochemical enzyme electrode monitoring technology, and glucose Electrochemical Measurement Technology accuracy rate height can avoid tradition to refer to that blood formula method of testing needs repeatedly to gather to refer to alleviate the patient suffering by blood on the one hand; On the other hand, can keep a period of time after the enzyme electrode implantation is subcutaneous, and the patient can not feel pain substantially when implanting, after implanting simultaneously, enzyme electrode pick off energy continuous collecting patient tissue liquid glucose data, and be converted to the blood glucose concentration data, and the glucose data of per minute in following 3-4 days can be provided continuously, really realize continuous glucose monitoring.
Claims (2)
1. Wicresoft's continuous glucose monitoring pick off comprises a needle-like formula reference electrode and at least one needle-like formula working electrode, and working electrode comprises conductive layer and enzyme membrane layer; It is characterized in that: also comprise pedestal, plug and adhesive, needle-like formula reference electrode and working electrode are arranged on pedestal one side, and plug is arranged on the pedestal opposite side, and the terminal of plug is connected with needle-like formula electrode, adhesive is arranged on pedestal one side, is positioned at homonymy with needle-like formula electrode.
2. Wicresoft according to claim 2 continuous glucose monitoring pick off is characterized in that: also comprise the adhesive cover layer, be used to cover the adhesive face of adhesive or be torn in use.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010206066974U CN201996544U (en) | 2010-11-15 | 2010-11-15 | Minimally invasive and continuous type monitoring sensor for glucose |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010206066974U CN201996544U (en) | 2010-11-15 | 2010-11-15 | Minimally invasive and continuous type monitoring sensor for glucose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201996544U true CN201996544U (en) | 2011-10-05 |
Family
ID=44699325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010206066974U Expired - Lifetime CN201996544U (en) | 2010-11-15 | 2010-11-15 | Minimally invasive and continuous type monitoring sensor for glucose |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201996544U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107874742A (en) * | 2012-06-08 | 2018-04-06 | 美敦力迷你迈德公司 | Application of the electrochemical impedance spectroscopy in sensing system, equipment and associated method |
| US11031114B2 (en) | 2014-12-04 | 2021-06-08 | Medtronic Minimed, Inc | Methods for operating mode transitions and related infusion devices and systems |
-
2010
- 2010-11-15 CN CN2010206066974U patent/CN201996544U/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107874742A (en) * | 2012-06-08 | 2018-04-06 | 美敦力迷你迈德公司 | Application of the electrochemical impedance spectroscopy in sensing system, equipment and associated method |
| CN107874742B (en) * | 2012-06-08 | 2021-03-19 | 美敦力迷你迈德公司 | Use of electrochemical impedance spectroscopy in sensor systems, devices, and related methods |
| US11031114B2 (en) | 2014-12-04 | 2021-06-08 | Medtronic Minimed, Inc | Methods for operating mode transitions and related infusion devices and systems |
| US11636938B2 (en) | 2014-12-04 | 2023-04-25 | Medtronic Minimed, Inc. | Methods for operating mode transitions and related infusion devices and systems |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Cheng et al. | A touch-actuated glucose sensor fully integrated with microneedle array and reverse iontophoresis for diabetes monitoring | |
| KR100328654B1 (en) | Biosensor, iontophoretic sampling system, and methods of use thereof | |
| CN105873514B (en) | Dynamic glucose harvester and host | |
| CN109199400B (en) | Electrochemical blood glucose sensor based on microneedle array | |
| CN207336426U (en) | A kind of biology sensor | |
| CA2482568A1 (en) | System and method for piercing dermal tissue | |
| CN208541312U (en) | Non-invasive blood glucose meter based on flexible biosensor | |
| Li et al. | Fully integrated wearable microneedle biosensing platform for wide-range and real-time continuous glucose monitoring | |
| CN114931378A (en) | Noninvasive blood glucose detection method | |
| Tianyi et al. | Micro interstitial fluid extraction and detection device integrated with the optimal extraction conditions for noninvasive glucose monitoring | |
| CN111150407A (en) | Wearable blood glucose meter | |
| CN201996544U (en) | Minimally invasive and continuous type monitoring sensor for glucose | |
| CN208171917U (en) | Noninvasive dynamics monitoring device based on multisensor pixel array | |
| US11733195B2 (en) | Electrochemical sensor for humoral detection and detection device | |
| CN113974615A (en) | Tissue fluid detection device and system thereof | |
| CN111387993B (en) | Sensor and detection system for minimally invasive detection of levodopa | |
| CN219578881U (en) | Glucose monitoring probe and glucose monitor | |
| CN110389163A (en) | Non-invasive blood glucose detection device based on multi-sensor pixel array | |
| CN217566069U (en) | Tissue fluid detection device and system | |
| CN115728369B (en) | A highly sensitive flexible breathable electrode for sweat lactate detection | |
| CN212546944U (en) | A sensor for minimally invasive detection of levodopa | |
| CN204542143U (en) | Miniature dynamic glucometer probe | |
| CN113598760B (en) | biological monitoring device | |
| CN211834409U (en) | Wearable Blood Glucose Meter | |
| KR102353059B1 (en) | Apparatus for measuring biometric data |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Zhuhai Funiya Medical Equipment Co., Ltd. Assignor: Princeton medical technology (Zhuhai) Co., Ltd. Contract record no.: 2018440000097 Denomination of utility model: Minimally invasive and continuous type monitoring sensor for glucose Granted publication date: 20111005 License type: Common License Record date: 20180726 |
|
| EE01 | Entry into force of recordation of patent licensing contract | ||
| CX01 | Expiry of patent term |
Granted publication date: 20111005 |
|
| CX01 | Expiry of patent term |