CN201436996U - Absorbable medical wrinkle-removing pad film - Google Patents
Absorbable medical wrinkle-removing pad film Download PDFInfo
- Publication number
- CN201436996U CN201436996U CN2009201189848U CN200920118984U CN201436996U CN 201436996 U CN201436996 U CN 201436996U CN 2009201189848 U CN2009201189848 U CN 2009201189848U CN 200920118984 U CN200920118984 U CN 200920118984U CN 201436996 U CN201436996 U CN 201436996U
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- China
- Prior art keywords
- film
- wrinkle
- medical
- film body
- absorbable medical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 230000037303 wrinkles Effects 0.000 claims abstract description 42
- 239000000463 material Substances 0.000 claims description 13
- 239000011148 porous material Substances 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 11
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 abstract description 9
- 229960000448 lactic acid Drugs 0.000 abstract description 7
- 231100000241 scar Toxicity 0.000 abstract description 3
- 238000005516 engineering process Methods 0.000 abstract description 2
- 210000001061 forehead Anatomy 0.000 abstract description 2
- 239000000203 mixture Substances 0.000 abstract description 2
- 208000032544 Cicatrix Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 210000004709 eyebrow Anatomy 0.000 abstract 1
- 210000000744 eyelid Anatomy 0.000 abstract 1
- 239000012567 medical material Substances 0.000 abstract 1
- 230000037387 scars Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 description 15
- 229920001577 copolymer Polymers 0.000 description 9
- 229920000747 poly(lactic acid) Polymers 0.000 description 6
- 210000001519 tissue Anatomy 0.000 description 5
- 238000001727 in vivo Methods 0.000 description 4
- 208000031481 Pathologic Constriction Diseases 0.000 description 3
- 238000002513 implantation Methods 0.000 description 3
- 239000004626 polylactic acid Substances 0.000 description 3
- 238000007920 subcutaneous administration Methods 0.000 description 3
- 210000001215 vagina Anatomy 0.000 description 3
- PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical compound O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 description 3
- 229920001661 Chitosan Polymers 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 238000005266 casting Methods 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 230000004098 cellular respiration Effects 0.000 description 2
- 238000010041 electrostatic spinning Methods 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 210000003608 fece Anatomy 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 238000004108 freeze drying Methods 0.000 description 2
- 230000004927 fusion Effects 0.000 description 2
- 239000007943 implant Substances 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 239000002207 metabolite Substances 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 238000005191 phase separation Methods 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 1
- 229920000954 Polyglycolide Polymers 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 239000003519 biomedical and dental material Substances 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 210000000589 cicatrix Anatomy 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 210000001951 dura mater Anatomy 0.000 description 1
- 210000002744 extracellular matrix Anatomy 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 239000004633 polyglycolic acid Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
Images
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- Materials For Medical Uses (AREA)
Abstract
The utility model discloses an absorbable medical wrinkle-removing pad film which comprises a film body. The film body is a planar film, at least two straight-through holes are distributed on the film body, and the aperture of the straight-through hole is 0.002-10mm. The film body adopts the absorbable medical material, preferably the PLA (poly DL-lactic acid), the PLGA (polylactic-co-glycolic acid), the PLCA (polylactic-co-caprolactone acid) and the blend of the above, and is obtained through the conventional film-forming technology. The absorbable medical wrinkle-removing pad film is applicable to removing of the wrinkles around the eyes, the wrinkles between the eyebrows, the forehead wrinkles, the nasolabial fold, the wrinkles at the lower eyelids and scars and has good biocompatibility and flexibility, obvious wrinkle-removing effect and safe use.
Description
Technical field
This utility model belongs to the biomaterial for medical purpose technical field, relates in particular to a kind of absorbable medical reduce wrinkle pad film.
Background technology
Absorbable medical film be a kind of be the medical high polymer multifunctional membrane that raw material is made with the absorbable material, quite extensive in surgical operation is used.That uses clinically at present has hyaluronate sodium, chitosan, chitosan film, polylactic acid membrane and a polylactic acid-polyglycolic acid film, because the operation kind difference of using, all different to the structural requirement of the requirement of material and film.The characteristics of absorbable medical film are biodegradable, the absorption and the metabolism of safety, and final metabolite is harmless and can excrete.In absorbable material, comparatively moderate with the degradation time of polylactic acid and copolymer analog biomedical material thereof, mechanical performance is also comparatively outstanding, thereby is widely used in fields such as bone tissue engineer, bone internal fixation material, pharmaceutical carrier, biomembrane.
In the beauty and shaping industry field, removing the common method that adopts of facial wrinkles is the injection completion method, and the material of filling is generally gel.Gel rubber material commonly used has hyaluronate sodium, takes off end collagen peptide etc.Their subject matter is the weak point of holding time, and wrinkle rebounds easily, and general wrinkle improvement effect is held time and is no more than 1 year.
Summary of the invention
It is a kind of easy to operate that this utility model provides, and the biology pad film that wrinkle improvement effect is good can be applied in beauty treatment reduce wrinkle field widely.
A kind of absorbable medical reduce wrinkle pad film comprises film body, is distributed with two clear openings on the film body at least; The pore size of described clear opening is 0.002-10mm.
Described film body can be made Any shape as required, is generally rectangle, circle or oval.Described through hole also can be made Any shape as required, is generally rectangle, circle or oval.
When clear opening was circular, its diameter was 0.002-10mm; When through hole was oval, its major axis and minor axis were 0.002-10mm; When through hole was rectangle or other shapes, the minimum 0.002mm of its inscribe diameter of a circle was to guarantee the permeability of film body.
Film body is generally planar film, i.e. flaky texture, and film body thickness is 0.01-2mm.
Described film body adopts a kind of absorbable material to make, and also can be to make after adopting multiple absorbable material blend.In raw material weight percentage ratio, can be
A) poly-DL-lactic acid (PLA) 50%-100%, poly (glycolide-co-lactide) (PLGA) copolymer 0-50%;
B) poly-DL-lactic acid (PLA) 50%-100%, polylactide caprolactone (PLCA) copolymer 0-50%;
Or c) poly-DL-lactic acid (PLA) 30%-60%, poly (glycolide-co-lactide) (PLGA) copolymer 0-40%, polylactide caprolactone (PLCA) copolymer 0-30%.
Above a), b), c) three kinds of schemes all adopt nontoxic absorbable material.
This utility model proposes with the absorbable biological film of being with clear opening first as the reduce wrinkle material.This film with existing be mainly used in anti, the biomembranous maximum difference of cerebral dura mater sticking patch is that the medical reduce wrinkle pad of this utility model film has straight-through hole, being convenient to film both sides tissue can promptly grow together.Though and existing anti blocking biomembrane etc. some also have micropore, do not lead directly to, otherwise do not have the anti effect, or do not have the effect that prevents leakage of body fluids.
The medical reduce wrinkle pad of this utility model film is applicable to canthus wrinkle, nasolabial fold, perioral aging lines, glabella stricture of vagina, cervical region wrinkle, forehead stricture of vagina, the removal of eye pouch wrinkle down, have excellent biological compatibility and pliability, corium and subcutaneous tissue have been isolated after the implantation, make skin corium form many new capillary vessel nets, the blood flow increase makes subcutaneous microcirculation improve the amount of having replenished extracellular matrix, can grow into by inducing cell, make cell plentiful, skin is glossy, and wrinkle improvement effect is kept and reached 8-10.The pad film has numerous aperture, and tissue can be grown into, avoids the vertical adhesion between histrionic muscles and the skin.
The medical reduce wrinkle pad of this utility model film is biodegradable, can be after 3 years by the absorption of tissue safety and metabolism, and final metabolite is harmless; Polylactic acid and copolymeric material thereof that the pad film uses are the inherent material of human body, and the lactic acid that body produces during to the human body tonic activity is similar, so its good biocompatibility; Medical reduce wrinkle pad film elasticity still is that pliability is all similar to soft tissue, and the feel quality is true to nature, does not affect the appearance.The surgery plastic aesthetic surgery wound of utilizing medical reduce wrinkle pad film to do is little, goes out insufficiency of blood, and is simple to operate, safety, and wrinkle improvement effect is obvious, and cicatrix (vestige) is not stayed on the surface, recovers fast, and the retention time is long.
Description of drawings
Fig. 1 is the structural representation of the medical reduce wrinkle pad of this utility model film;
Fig. 2 is the structural representation of the another kind of embodiment of the medical reduce wrinkle pad of this utility model film.
The specific embodiment
Referring to Fig. 1, the absorbable medical reduce wrinkle pad film of this utility model comprises film body 2, and film body is for being the rectangle plane film, and film body thickness D is 0.05mm.
The width of planar film is 5cm, and length is 6cm.Be distributed with 16 clear openings 1 on the film body, through hole is circular, and the pore size of through hole is 2mm.
Film body contains following main component, shared share by weight percentage: poly-DL-lactic acid (PLA) 50%-100%, poly (glycolide-co-lactide) (PLGA) copolymer 0-50%, film body obtains by the film technique of routine.Film technique commonly used comprises fusion or solution casting method, non-woven fibre cloth method, freeze-drying, method of electrostatic spinning, phase separation method etc.Clear opening on the film body can form by methods such as conventional mechanical punching or laser borings.
During operation, an osculum is cut at the canthus that needs reduce wrinkle, the absorbable medical reduce wrinkle pad film of this utility model is curled put into otch to launch the implantation canthus more subcutaneous.This absorbable medical reduce wrinkle pad film biocompatibility is good, has no side effect, and it is non-stimulated to organizing to implant, and can not cause the human body rejection by the complete degraded and absorbed of autologous tissue; The effect that smoothes away wrinkles is got instant result and has been avoided operative scar; The operation back is true to nature naturally, no foreign body profile and foreign body sensation, and surgical effect presents immediately; Effectively supporting time is long, the complete in vivo degraded and absorbed of reduce wrinkle evil spirit pad in 3 years, and final catabolite is CO2 and HO2, through Cellular respiration, excretes by urine, perspiration or feces, noresidue in vivo, safe and effective.
Referring to Fig. 2, the another kind of embodiment of the absorbable medical reduce wrinkle pad film of this utility model comprises film body 2, and film body is the circular flat film, and film body thickness D is 0.1mm.
The radius of planar film is 6cm.Be distributed with 14 clear openings 1 on the film body, through hole is oval, and the major semiaxis of through hole is 2mm, and semi-minor axis is 1.5mm.
Film body contains following main component, shared share is by weight percentage: poly-DL-lactic acid (PLA) 30%-60%, poly (glycolide-co-lactide) (PLGA) copolymer 0-40%, polylactide caprolactone (PLCA) copolymer 0-30%, film body obtains by the film technique of routine.Film technique commonly used comprises fusion or solution casting method, non-woven fibre cloth method, freeze-drying, method of electrostatic spinning, phase separation method etc.
During operation, the glabella stricture of vagina of reduce wrinkle will be needed: in brows, do a little otch, the absorbable medical reduce wrinkle pad film of this utility model curled put into otch to launch the implantation canthus more subcutaneous, this absorbable medical reduce wrinkle pad film biocompatibility is good, have no side effect, it is non-stimulated to organizing to implant, and can not cause the human body rejection by the complete degraded and absorbed of autologous tissue; The effect that smoothes away wrinkles is got instant result and has been avoided operative scar; The operation back is true to nature naturally, no foreign body profile and foreign body sensation, and surgical effect presents immediately; Effectively supporting time is long, the complete in vivo degraded and absorbed of reduce wrinkle evil spirit pad after 3 years, and final catabolite is CO2 and H2O, through Cellular respiration, excretes by urine, perspiration or feces, noresidue in vivo, safe and effective.
Claims (5)
1. an absorbable medical reduce wrinkle pad film comprises film body, it is characterized in that, is distributed with two clear openings on the described film body at least; The pore size of described clear opening is 0.002-10mm.
2. medical reduce wrinkle pad film as claimed in claim 1 is characterized in that described film body is rectangle, circle or oval.
3. medical reduce wrinkle pad film as claimed in claim 1 or 2 is characterized in that described film body thickness is 0.01-2mm.
4. medical reduce wrinkle pad film as claimed in claim 1 is characterized in that described through hole is rectangle, circle or oval.
5. medical reduce wrinkle pad film as claimed in claim 1 is characterized in that described film body is made by absorbable material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009201189848U CN201436996U (en) | 2009-04-30 | 2009-04-30 | Absorbable medical wrinkle-removing pad film |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009201189848U CN201436996U (en) | 2009-04-30 | 2009-04-30 | Absorbable medical wrinkle-removing pad film |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201436996U true CN201436996U (en) | 2010-04-14 |
Family
ID=42398976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009201189848U Expired - Lifetime CN201436996U (en) | 2009-04-30 | 2009-04-30 | Absorbable medical wrinkle-removing pad film |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201436996U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104717938A (en) * | 2012-05-10 | 2015-06-17 | 株式会社太平洋制药 | Filler for removing wrinkles |
| CN104984468A (en) * | 2015-07-24 | 2015-10-21 | 陈洁 | Biological pad for treating damages to rotator cuff and use method thereof |
| CN105078612A (en) * | 2015-08-19 | 2015-11-25 | 深圳市大族三维科技有限公司 | Temple prosthesis and manufacturing method thereof |
| CN106074003A (en) * | 2016-06-13 | 2016-11-09 | 浙江长兴惠龙医疗科技有限公司 | The manufacture method of Medical isolating film, Medical isolating film and medical absorbent pads |
-
2009
- 2009-04-30 CN CN2009201189848U patent/CN201436996U/en not_active Expired - Lifetime
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104717938A (en) * | 2012-05-10 | 2015-06-17 | 株式会社太平洋制药 | Filler for removing wrinkles |
| CN104717938B (en) * | 2012-05-10 | 2017-07-18 | 株式会社瑗丝特兰 | filler for removing wrinkle |
| CN104984468A (en) * | 2015-07-24 | 2015-10-21 | 陈洁 | Biological pad for treating damages to rotator cuff and use method thereof |
| CN105078612A (en) * | 2015-08-19 | 2015-11-25 | 深圳市大族三维科技有限公司 | Temple prosthesis and manufacturing method thereof |
| CN106074003A (en) * | 2016-06-13 | 2016-11-09 | 浙江长兴惠龙医疗科技有限公司 | The manufacture method of Medical isolating film, Medical isolating film and medical absorbent pads |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: ZHEJIANG APELOA HOME BIOMEDICAL MATERIALS CO., LTD Free format text: FORMER OWNER: PULUO MEDICINES TECH CO., LTD., ZHEJIANG Effective date: 20111111 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20111111 Address after: 322118 Hengdian Industrial Zone, Zhejiang, Dongyang Co-patentee after: Chengdu Organic Chemicals Co., Ltd., Chinese Academy of Sciences Patentee after: Zhejiang Apeloa Jiayuan Bio-pharmaceutical Material Co., Ltd. Co-patentee after: Wang Yueling Address before: 322118 Hengdian Industrial Zone, Zhejiang, Dongyang Co-patentee before: Chengdu Organic Chemicals Co., Ltd., Chinese Academy of Sciences Patentee before: Puluo Medicines Tech Co., Ltd., Zhejiang Co-patentee before: Wang Yueling |
|
| C56 | Change in the name or address of the patentee |
Owner name: ZHEJIANG WEDU MEDICAL INSTRUMENTS CO., LTD. Free format text: FORMER NAME: ZHEJIANG APELOA JIAYUAN BIOMEDICAL MATERIAL CO., LTD. |
|
| CP01 | Change in the name or title of a patent holder |
Address after: 322118 Hengdian Industrial Zone, Zhejiang, Dongyang Patentee after: Zhejiang Wedu Medical Equipment Co., Ltd. Patentee after: Chengdu Organic Chemicals Co., Ltd., Chinese Academy of Sciences Patentee after: Wang Yueling Address before: 322118 Hengdian Industrial Zone, Zhejiang, Dongyang Patentee before: Zhejiang Apeloa Jiayuan Bio-pharmaceutical Material Co., Ltd. Patentee before: Chengdu Organic Chemicals Co., Ltd., Chinese Academy of Sciences Patentee before: Wang Yueling |
|
| CX01 | Expiry of patent term |
Granted publication date: 20100414 |
|
| CX01 | Expiry of patent term |