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CN201244025Y - Detecting device integrated with light sound ultrasonic excitation and sensor - Google Patents

Detecting device integrated with light sound ultrasonic excitation and sensor Download PDF

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Publication number
CN201244025Y
CN201244025Y CNU2008201130905U CN200820113090U CN201244025Y CN 201244025 Y CN201244025 Y CN 201244025Y CN U2008201130905 U CNU2008201130905 U CN U2008201130905U CN 200820113090 U CN200820113090 U CN 200820113090U CN 201244025 Y CN201244025 Y CN 201244025Y
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ring
excitation
detection
ultrasonic
semiconductor laser
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CNU2008201130905U
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Chinese (zh)
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刘国栋
曾吕明
徐景坤
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0093Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
    • A61B5/0095Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Acoustics & Sound (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)

Abstract

The utility model relates to a detection device for the integrative excitation and sensing of photoacoustic ultrasound. An acoustic insulating layer, an acoustic interlay, a miniaturized semiconductor laser tube, a Fourier lens, a cylindrical lens, a protective film and circular polycyclic array sensors are arranged in an outer casing and are all arranged on the same axis line to form an integrative coaxial confocal structure, the circular polycyclic array sensor can carry out time-sharing excitation to generate an ultrasonic signal and receive an ultrasonic echoed signal and a photoacoustic signal so as to realize the single or combined detection of the photoacoustic ultrasound of A-mode dynamic scan. The utility model integrates the excitation and the sensing of photoacoustic ultrasound into a whole, can greatly improve the excitation and sensing efficiency of the photoacoustic ultrasound, improves the detection depth while effectively lowering the requirements of laser energy, has high detection sensitivity and enables the device to have miniaturized and practical structure so as to have portability, simple and convenient operation and lower cost. The utility model is widely applicable to fields, such as blood oxygen detection, blood glucose detection, HIFU (High Intensity Focused Ultrasound) treatment, effect monitoring, industrial fault detection, and the like.

Description

Light sound ultrasonic excitation and sensing integrated checkout gear
Technical field
This utility model relates to biomedical measurement and technical field of medical instruments, particularly relates to a kind of light sound ultrasonic excitation and sensing integrated checkout gear.
Background technology
Also there are a lot of difficulties in the ultransonic multiparameter combined detection of optoacoustic at present, for example consider the damage threshold of biological tissue, incident laser can not be too strong, again owing to organize strong scattering and the absorption of top layer to light, arrive the light intensity decreasing of deep tissues, so effectively the launching efficiency of raising optoacoustic is a problem that needs solution in a hurry; In addition, optoacoustic detection is based on optoacoustic effect and supersonic sounding is based on piezoelectric effect, there is certain difficulty in the system integration and the miniaturization of two cover different principle.
" Optoacoustic and Ultrasonic Co-Image with a Linear TransducerArray " Opt.Lett.29,1760-1762,2004. reported the optoacoustic ultrasonic in combination formation method that shakes first linear array detector based on 320, but that the detection method of this lateral mode is difficult to be applied to is clinical." Combined ultrasound and optoacoustic system for real-timehigh-contrast vascular imaging in vivo " IEEE Trans.Med.Imaging 24,436-440,2005. reported that based on the optoacoustic ultrasonic in combination formation method of detection mode dorsad having adopted pick off is 64 linear array detector and the laser energy output side optical fiber formulas of shaking unit." Integratedsystem for ultrasonic; photoacoustic and elasticity imaging, " Proc.SPIE, 6147,61470H1-8,2006. have reported the joint imaging method of optoacoustic based on the forward direction detection mode, ultrasonic and elastic modelling quantity.But the scope of application of forward direction detection mode is narrower, and above method all is to adopt linear array detector as transducing part, detection mode is B-scan, light sound ultrasonic excitation and sensing can't realize the coaxial confocal structure, therefore the efficient of photo-acoustic excitation and detection is not high, need more powerful solid state laser that the optoacoustic excitation energy is provided, and the solid state laser of large volume can't realize encouraging the integrated and miniaturization with sensing, actual popularizing application prospect has been subjected to very big restriction.
Summary of the invention
The technical problems to be solved in the utility model provides a kind of light sound ultrasonic excitation and sensing integrated checkout gear, the ultrasonic single or combined detection of optoacoustic can be realized, the detection of blood oxygen, blood sugar test, HIFU treatment and fields such as effect monitoring, industrial flaw detection can be widely used in.
For solving the problems of the technologies described above, the technical solution of the utility model is: a kind of light sound ultrasonic excitation and sensing integrated checkout gear, top and middle part at shell are provided with the acoustics insulating barrier, center of top at the acoustics insulating barrier is provided with semiconductor laser tube, in the central authorities of acoustics insulating barrier, the below that is positioned at semiconductor laser tube is provided with fourier transform lens; Be provided with the sound absorption pad under the bottom of shell, acoustics insulating barrier, in the central authorities of sound absorption pad, the below that is positioned at fourier transform lens is provided with cylindrical lens, and the bottom surface of cylindrical lens is provided with protecting film; The hollow inner ring sleeve of ring-type multi-ring array pick off is contained in the bottom of cylindrical lens; The center of semiconductor laser tube, fourier transform lens, cylindrical lens, multi-ring array pick off all is positioned on the same axis, and integrated being packaged in the shell constitutes incorporate coaxial confocal structure.Described semiconductor laser tube (1) is the quasiconductor pulsed laser diode, and the quasiconductor pulsed laser diode is operated in one or more wavelength that ultraviolet is selected to the infra-red range.Described semiconductor laser tube, fourier transform lens and cylindrical lens are formed photo-acoustic excitation source and light path lens combination, and light path system can conversion produce focusing or parallel laser beam, passes the hollow internal ring of protecting film and multi-ring array pick off, the detected sample of directive.Planar array that described multi-ring array pick off is a hollow or concavo-convex battle array, each ring of multi-ring array pick off is cut into α * k=2 π, (k=1,2, n) arc of the radian unit of shaking, wherein a is each arc corresponding radian of unit that shakes, and k is the arc of cutting first number that shakes, and each arc unit's 14 electrodes 12 by lead and signal processor that shake are electrically connected.Described multi-ring array pick off adopts piezoelectric, comprises Lithium metaniobate, composite, piezoelectric ceramics or the making of PVDF thin film; Described multi-ring array pick off can the excitation of timesharing ground produce ultrasonic signal, receive ultrasound echo signal and receive photoacoustic signal, realizes the ultrasonic single or combined detection of optoacoustic of A type dynamic scan.
Work process of the present utility model is: externally control signal triggers down, the semiconductor laser tube excitation produces pulse laser, Wavelength of Laser, pulsewidth and repetition rate can be selected as required, laser energy is by behind the light path lens combination collimation, sees through protecting film and is radiated and excites the generation photoacoustic signal on the sample; Control signal triggers the multi-ring array pick off simultaneously and surveys photoacoustic signal, realizes exciting and sensing of photoacoustic signal; At the next cycle of control signal, control signal triggers multi-ring array sensor emission ultrasonic signal, begins to receive ultrasound echo signal after the time-delay, realizes exciting and sensing of ultrasonic signal; By optoacoustic data and the ultrasonic echo data that signal and algorithm process collect, can obtain to survey the target value of sample at the ultrasonic A type dynamic scan single or associating of the optoacoustic of depth direction.
The beneficial effects of the utility model are: this device light harvesting sound is ultransonic to excite and is sensed as one, and photo-acoustic excitation source, light path lens combination and multi-ring array pick off form the coaxial confocal structure; Can realize that the ultrasonic A type dynamic scan single or associating of optoacoustic surveys, can improve greatly that optoacoustic is ultransonic to be excited and sensing efficient, when effectively reducing the laser energy requirement, improves the acoustics insulating barrier investigation depth, measure highly sensitive, and make apparatus structure miniaturization and practicability, be easy to carry, easy and simple to handle, cost is lower.This utility model can be widely used in the detection of blood oxygen, blood sugar test, HIFU treatment and fields such as effect monitoring, industrial flaw detection.
Description of drawings
Fig. 1 is a structural profile sketch map of the present utility model.
Fig. 2 is the sketch map that is electrically connected of this utility model multi-ring array pick off.
Fig. 3 is the structural representation of a ring of this utility model multi-ring array pick off.
The specific embodiment
The utility model is described in further detail below in conjunction with drawings and Examples.
Embodiment; A kind of light sound ultrasonic excitation and sensing integrated checkout gear, top and middle part at shell 10 are provided with acoustics insulating barrier 9, center of top at acoustics insulating barrier 9 is provided with semiconductor laser tube 1, and in the central authorities of acoustics insulating barrier 9, the below that is positioned at semiconductor laser tube 1 is provided with fourier transform lens 2; Be provided with sound absorption pad 8 under the bottom of shell 10, acoustics insulating barrier 9, in the central authorities of sound absorption pad 8, the below that is positioned at fourier transform lens 2 is provided with cylindrical lens 3, and the bottom surface of cylindrical lens 3 is provided with protecting film 4; The hollow inner ring sleeve of ring-type multi-ring array pick off 7 is contained in the bottom of cylindrical lens 3; Semiconductor laser tube 1, the center of fourier transform lens 2, cylindrical lens 3, multi-ring array pick off 7 all are positioned on the same axis 6, and integrated being packaged in the shell 10 constitutes incorporate coaxial confocal structure.Said elements is integrated to be fixed in the crust of the device 10; Protecting film 4 has printing opacity and water-proof function, can protect inner optics; Acoustics insulating barrier 9 is used to prevent that ultrasonic energy from reaching crust of the device 10 and causing the reflection interference signal, and improves investigation depth when effectively reducing the laser energy requirement.
Semiconductor laser tube 1 select for use pulse semiconductor laser diode (PGAS1S24, Hoffo), operation wavelength is 905nm, peak power is 49W, pulsewidth is 150ns, single pulse energy is about 7.3uJ.
Semiconductor laser tube 1, fourier transform lens 2 and cylindrical lens 3 are formed photo-acoustic excitation source and light path lens combination, and light path system can conversion produce focusing or parallel laser beam 5, passes the hollow internal ring of protecting film 4 and multi-ring array pick off 7, the detected sample of directive.
Multi-ring array pick off 7 is the concavo-convex battle array of hollow, and each ring of multi-ring array pick off 7 is cut into k=16 the homalographic arc unit 14 of shaking, and respectively shaking is provided with spacing 13 between the unit, and each arc corresponding radian 15 of unit that shakes is a=π/8.Each arc unit 14 of shaking is electrically connected by lead 11 electrodes 12 with signal processor.
Multi-ring array pick off 7 adopts piezoelectric ceramics to make, the work centre frequency is 1MHz, the number of ring is 7, be designed to the equally spaced planar rings battle array of the homalographic structure of hollow, ring spacing is not more than half-wavelength, and wherein the velocity of sound is decided to be 1500m/s, and each arc unit 14 of shaking is electrically connected by lead 11 electrodes 12 with signal processor, can realize that the excitation of timesharing ground produces ultrasonic signal, receives ultrasound echo signal and receives photoacoustic signal, can realize the ultrasonic single or combined detection of optoacoustic of a-scan.

Claims (4)

1, light sound ultrasonic excitation and sensing integrated checkout gear, it is characterized in that: top and middle part at shell (10) are provided with acoustics insulating barrier (9), center of top at acoustics insulating barrier (9) is provided with semiconductor laser tube (1), central authorities in acoustics insulating barrier (9), the below that is positioned at semiconductor laser tube (1) is provided with fourier transform lens (2); Be provided with sound absorption pad (8) under the bottom of shell (10), acoustics insulating barrier (9), in the central authorities of sound absorption pad (8), the below that is positioned at fourier transform lens (2) is provided with cylindrical lens (3), and the bottom surface of cylindrical lens (3) is provided with protecting film (4); The hollow inner ring sleeve of ring-type multi-ring array pick off (7) is contained in the bottom of cylindrical lens (3); The center of semiconductor laser tube (1), fourier transform lens (2), cylindrical lens (3), multi-ring array pick off (7) all is positioned on the same axis (6), and integrated being packaged in the shell (10) constitutes incorporate coaxial confocal structure; Multi-ring array pick off (7) can the excitation of timesharing ground produce ultrasonic signal, receive ultrasound echo signal and receive photoacoustic signal, realizes the ultrasonic single or combined detection of optoacoustic of A type dynamic scan.
2, light sound ultrasonic excitation according to claim 1 and sensing integrated checkout gear, it is characterized in that: described semiconductor laser tube (1) is for the quasiconductor pulsed laser diode, and the quasiconductor pulsed laser diode is operated in one or more wavelength that ultraviolet is selected to the infra-red range.
3, light sound ultrasonic excitation according to claim 1 and sensing integrated checkout gear; it is characterized in that: described semiconductor laser tube (1), fourier transform lens (2) and cylindrical lens (3) are formed photo-acoustic excitation source and light path lens combination; light path system can conversion produce focusing or parallel laser beam (5); pass the hollow internal ring of protecting film (4) and multi-ring array pick off (7), the detected sample of directive.
4, light sound ultrasonic excitation according to claim 1 and sensing integrated checkout gear, it is characterized in that: described multi-ring array pick off (7) is the planar array of hollow or concavo-convex battle array, each ring of multi-ring array pick off (7) is cut into α * k=2 π, (k=1,2, n) arc of the radian unit of shaking, wherein a is each arc corresponding radian of unit that shakes, k is arc first number that shakes of cutting, and each arc electrode (12) of unit (14) by lead (11) and signal processor that shake is electrically connected.
CNU2008201130905U 2008-07-03 2008-07-03 Detecting device integrated with light sound ultrasonic excitation and sensor Expired - Lifetime CN201244025Y (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100571626C (en) * 2008-07-03 2009-12-23 刘国栋 Light sound ultrasonic excitation and sensing integrated checkout gear
CN101936953A (en) * 2010-09-02 2011-01-05 华南理工大学 System and method for measuring the concentration of fruit juice sugar components based on pipeline time delay
CN103228201A (en) * 2010-07-28 2013-07-31 柯惠有限合伙公司 Light focusing continuous wave photoacoustic spectroscopy and its applications to patient monitoring
CN104586356A (en) * 2013-10-31 2015-05-06 佳能株式会社 Subject information acquisition apparatus
CN107228904A (en) * 2017-07-21 2017-10-03 江西科技师范大学 A kind of photic ultrasonic non-invasive glucose monitoring device and method
CN110596010A (en) * 2019-10-24 2019-12-20 南昌洋深电子科技有限公司 Micro-lens array capable of receiving and transmitting ultrasound

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100571626C (en) * 2008-07-03 2009-12-23 刘国栋 Light sound ultrasonic excitation and sensing integrated checkout gear
CN103228201A (en) * 2010-07-28 2013-07-31 柯惠有限合伙公司 Light focusing continuous wave photoacoustic spectroscopy and its applications to patient monitoring
CN101936953A (en) * 2010-09-02 2011-01-05 华南理工大学 System and method for measuring the concentration of fruit juice sugar components based on pipeline time delay
CN101936953B (en) * 2010-09-02 2012-07-18 华南理工大学 Pipeline delay-based system and method for measuring concentrations of components of fruit juice sugar
CN104586356A (en) * 2013-10-31 2015-05-06 佳能株式会社 Subject information acquisition apparatus
CN107228904A (en) * 2017-07-21 2017-10-03 江西科技师范大学 A kind of photic ultrasonic non-invasive glucose monitoring device and method
CN110596010A (en) * 2019-10-24 2019-12-20 南昌洋深电子科技有限公司 Micro-lens array capable of receiving and transmitting ultrasound
CN110596010B (en) * 2019-10-24 2022-07-08 南昌洋深电子科技有限公司 Micro-lens array capable of receiving and transmitting ultrasound

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C14 Grant of patent or utility model
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AV01 Patent right actively abandoned

Effective date of abandoning: 20080703

C25 Abandonment of patent right or utility model to avoid double patenting