CN201091718Y

CN201091718Y - Ampoule for liquid jet injector without needle

Info

Publication number: CN201091718Y
Application number: CNU2007201134530U
Authority: CN
Inventors: 陈凯
Original assignee: Individual
Current assignee: HENAN SHUGANG JIANSHI MEDICAL DEVICES GROUP CO Ltd
Priority date: 2007-08-27
Filing date: 2007-08-27
Publication date: 2008-07-30
Anticipated expiration: 2017-08-27

Abstract

The utility model discloses an ampoule applied to a liquid needleless injector and belongs to the technical field of subcutaneous administration equipment in medical appliances. The ampoule comprises a cylinder body the front end of which is provided with an injection head; a cavity with a closed front end and an open rear end is arranged in the cylinder body; a jet orifice which is communicated with the injection head is arranged on the front wall of the cavity; for matching purpose, a pull-push rod with a seal ring and a piston at the front end is arranged in the cavity. The jet orifice is a porous structure with no fewer than two orifices, and the forward extension line of the corresponding axle of each jet orifice is converged into a focus in the axial direction. The ampoule applied to liquid needleless injectors of the utility model has simple structure and can control injection depth and effectively reduce the phenomenon that strong reaction occurs during the injection process with the jet liquid injectors.

Description

The ampoule that is used for the needleless injection of liquids device

Technical field

The utility model discloses a kind of ampoule that is used for the needleless injection of liquids device, belong to subcutaneous administration device technique field in the medical device.

Background technology

The needleless injection of liquids device moves to maturity at medical field, and it is to produce the subcutaneous tissue that high-speed jet directly enters into the people by the powered medicine.As shown in Figure 1, the needleless injector of a standard is made up of two parts usually: be used for sucking medicine, splendid attire medicine and launch ampoule 1 ' (injection tube) of medicine, and can produce when triggering the power set 2 of thrust '.Though the needleless injection of liquids technology has lot of advantages and wide application prospect, but the phenomenon of big injection reaction is appearred in the needleless injection of liquids device that uses ubiquity minority in clinical use by the injector at present, show as once in a while pain, discomfort, local anaphylaxis, can produce petechiae, ecchymosis when serious.This has limited popularizing of needleless injection of liquids technology to a great extent.It is generally acknowledged that this phenomenon is with relevant by the individual variation of injection skin.As shown in Figure 2, the high-speed jet 3 that miniature spray-hole produces ' at first can be to skin 4 ' destroy, enter skin 4 ' back subcutaneous tissue be extended to medicine expanded body 5 '.The difference of skin characteristic can cause injection depth h ' difference between individuality, and dark excessively injection depth h ' can touch subcutaneous nerve and blood capillary, causes local pain or subcutaneous hemorrhage.Therefore, control injection depth h ' reduces big injection reaction appears in the needleless injection of liquids device in injection process effective way.

The miniature spray-hole of existing needleless injection of liquids device ampoule front end all is a single hole, or parallel loose structure, as applicant's preposition patent " the needleless injector " (patent No.: ZL200620105022.5).Ampoule injection depth in injection process of this single hole or parallel loose structure can change with the individual difference of human body skin, is difficult to control.

The utility model content

In order to overcome the shortcoming that exists in the above-mentioned prior art, this utility model provides a kind of simple in structure, the ampoule that is used for the needleless injection of liquids device that can control injection depth.

To achieve these goals, the technical scheme that this utility model adopted is: a kind of ampoule that is used for the needleless injection of liquids device, comprise that front end has the cylindrical shell of injection head, be provided with the chamber of front end sealing, open rearward end in the cylindrical shell, the ante-chamber wall of chamber is provided with the spray-hole that is connected with injection head, cooperate the push-pull bar that is provided with front end band sealing ring and piston in the chamber, described spray-hole is to be no less than two loose structure, and the respective shaft of each spray-hole forward extended line pool a focus in the axial direction.Because the medicine expanded body that injection produces merges together, as long as enough motive forces are arranged, can control within the specific limits substantially by injection depth in actual injection for the needleless injector ampoule of this structure.The ampoule injection depth of this structure depends on the focal position of converging.Like this, at the subcutaneous injection of different pharmaceutical, different human body position, can control injection depth by the accumulative position of design ampoule spray-hole.Certainly injection depth also with the dosage of injection, propel power and the spray-hole geometry is relevant, but this design can be eliminated the influence of individual character skin difference to injection depth to a certain extent.In addition will be in drug reservoir of subcutaneous formation by the polymerization of multiply inclination jet, to a certain degree the medicine injection (as the part vaccine injection) of sustained release is highly beneficial to needs for this.

As the further setting of such scheme, described each spray-hole is at arranged radially upper edge circumference uniform distribution.

This utility model also comprises by entry needle and is installed in the entry needle lower end and has the adaptor that the needle stand of female thread is formed; The front end side wall of described cylindrical shell is provided with the joint stricture of vagina that can be connected with adaptor.When being provided with of joint stricture of vagina can solve injection head because of excessive entry needle that can't the general size of socket, can get it filled with the mode of adaptor.

Described spray-hole is two, is uniformly distributed in the injection head both sides; Perhaps be three, and be axial parallel, radially become equilateral triangle to distribute; Perhaps be four, and be axial parallel, radially quadrate distribution.The increase of spray-hole quantity can be got it filled and administration faster, can increase injected dose simultaneously, and the quantity that increases spray-hole in addition like this has been equivalent to increase the jet of same speed, and dispergated multiple jets helps the medicine absorption in vivo more.

The axial slices of described spray-hole is shaped as parallel type or one of shrinkage type or scaling type.According to hydromechanical principle, fluid can cause energy loss when flowing into the injection micropore from big caliber chamber.With respect to the spray-hole of parallel type, the spray-hole energy loss of shrinkage type is smaller, thereby flow velocity also can be soon.But the spray-hole of parallel type or shrinkage type no matter, when pressure was enough big, its muzzle velocity can not surpass the velocity of sound, and the spray-hole of scaling type, its fluid issuing speed just can surpass the velocity of sound.

Description of drawings

Below in conjunction with the drawings and specific embodiments this utility model is described in further detail.

Fig. 1 is the structural representation of standard needleless injector;

Fig. 2 enters the sketch map of skin by the spray-hole of existing needleless injector ampoule for medicament;

Fig. 3 is used for the structural representation of the ampoule of needleless injection of liquids device for this utility model;

Fig. 4 is the A portion enlarged drawing of Fig. 3, and wherein spray-hole is three;

Fig. 5 is the right view of Fig. 4;

Fig. 6 is the structural representation of adaptor;

Structural representation when Fig. 7 gets it filled for socket entry needle on the injection head;

Fig. 8 is the right view with the ampoule of two spray-holes;

Fig. 9 is the right view with the ampoule of four spray-holes;

Figure 10 is the axial slices structural representation of parallel type spray-hole;

Figure 11 is the axial slices structural representation of shrinkage type spray-hole;

Figure 12 is the axial slices structural representation of scaling type spray-hole;

Figure 13 enters the sketch map of skin by the spray-hole among Fig. 4 for medicament.

The specific embodiment

As Fig. 3, Fig. 4, shown in Figure 5, this utility model is used for the ampoule of needleless injection of liquids device, comprise that front end has the cylindrical shell 2 of injection head 4, be provided with the chamber 1 of front end sealing, open rearward end in the cylindrical shell 2, the ante-chamber wall 3 of chamber 1 is provided with the spray-hole 6 that is connected with injection head 4, cooperates the push-pull bar 11 that is provided with front end band sealing ring 12 and piston 13 in the chamber 1.Wherein, spray-hole 6 is three, and each spray-hole 6 is at arranged radially upper edge circumference uniform distribution, and the respective shaft of each spray-hole 6 forward extended line 5 pool a focus in the axial direction.

As shown in Figure 6, this utility model is used for the ampoule of needleless injection of liquids device, also comprises by entry needle 14 and is installed in entry needle 14 lower ends and has the adaptor 17 that the needle stand 15 of female thread 16 is formed.Simultaneously, as Fig. 3, Fig. 4, shown in Figure 5, also be provided with the joint stricture of vagina 7 that can be connected with adaptor 17 on the front end side wall of cylindrical shell 2.During and entry needle 14 that can't socket general size bigger than normal, adaptor 17 covers can be received on the joint stricture of vagina 7 and be got it filled when injection head 4.

As shown in Figure 7, when the size of injection head 4 is stock size, entry needle 14 that can directly socket is general on injection head 4.When getting it filled, the backshank of entry needle 14 is socketed on the injection head 4, needle point inserts medicine bottle 18, pulling push-pull bar 11, and medicament will be inhaled in the chamber 1 by spray-hole 6.

As shown in Figure 8, spray-hole 6 can also be two, is uniformly distributed in injection head 4 both sides.

As shown in Figure 9, spray-hole 6 can also be four, and is axial parallel, radially quadrate distribution.

Shown in Figure 10,11,12, the axial slices shape of spray-hole 6 can be one of parallel type, shrinkage type, scaling type.

As shown in figure 13, medicament produces 8 pairs of skins 10 of three road high-speed jets by three spray-holes 6 and destroys under the thrust of power set, enters skin 10 backs and is extended to medicine expanded body 9 and merges together at subcutaneous tissue.Therefore, injection depth h can control within the specific limits substantially.

Claims

1. ampoule that is used for the needleless injection of liquids device, comprise that front end has the cylindrical shell of injection head (4) (2), be provided with the chamber (1) of front end sealing, open rearward end in the cylindrical shell (2), the ante-chamber wall (3) of chamber (1) is provided with the spray-hole (6) that is connected with injection head (4), cooperate the push-pull bar (11) that is provided with front end band sealing ring (12) and piston (13) in the chamber (1), it is characterized in that: described spray-hole (6) is for to be no less than two loose structure, and the respective shaft of each spray-hole (6) forward extended line (5) pool a focus in the axial direction.

2. according to the described ampoule that is used for the needleless injection of liquids device of claim 1, it is characterized in that: described each spray-hole (6) is at arranged radially upper edge circumference uniform distribution.

3. according to the described ampoule that is used for the needleless injection of liquids device of claim 1, it is characterized in that: also comprise by entry needle (14) and be installed in entry needle (14) lower end and have the adaptor (17) that the needle stand (15) of female thread (16) is formed; The front end side wall of described cylindrical shell (2) is provided with the joint stricture of vagina (7) that can be connected with adaptor (17).

4. according to the described ampoule that is used for the needleless injection of liquids device of claim 1, it is characterized in that: described spray-hole (6) is three, and is axial parallel, radially becomes equilateral triangle to distribute.

5. according to the described ampoule that is used for the needleless injection of liquids device of claim 1, it is characterized in that: described spray-hole (6) is two, is uniformly distributed in injection head (4) both sides.

6. according to the described ampoule that is used for the needleless injection of liquids device of claim 1, it is characterized in that: described spray-hole (6) is four, and is axial parallel, radially quadrate distribution.

7. according to claim 1 or 2 or 4 or the 5 or 6 described ampoules that are used for the needleless injection of liquids device, it is characterized in that: the axial slices of described spray-hole (6) is shaped as parallel type or one of shrinkage type or scaling type.