CN201094810Y - Electromagnetic field and ultrasound wave composite device for curing osteoporosis - Google Patents
Electromagnetic field and ultrasound wave composite device for curing osteoporosis Download PDFInfo
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- CN201094810Y CN201094810Y CNU2007201491947U CN200720149194U CN201094810Y CN 201094810 Y CN201094810 Y CN 201094810Y CN U2007201491947 U CNU2007201491947 U CN U2007201491947U CN 200720149194 U CN200720149194 U CN 200720149194U CN 201094810 Y CN201094810 Y CN 201094810Y
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Abstract
The utility model provides a device compound of electromagnetic field and ultrasonic to cure osteoporosis. The device includes a power system, a signal generating device supplied power by the power system, at least one electromagnetic field curing head and one ultrasonic curing head driven by the signal generating device. The electromagnetic field generating device of the utility model can integrally cure the osteoporosis, enhance the osseous density of the human body, change the electricity and chemical environments of the osseous tissues as well as affect and correct the growth, repairing and maintenance of the osseous tissues. An ultrasonic electropult irradiates the part with a lower osseous density or fracture, promotes the growth of the osseous tissues, shortens the osseous wound healing time caused by osteoporosis and improves the nonunion cure rate. Applying the comprehensive curing scheme from integral to partial to cure the osteoporosis and promote the healing of the osseous wound of osteoporosis. The utility model is convenient to use, has a good comprehensive curing effect and is suitable for various physiques and crowds.
Description
Technical field
This utility model relates to a kind of medical apparatus and instruments, specifically a kind of device that uses low frequency electromagnetic field and low-intensity pulse ultrasonic wave combination therapy osteoporosis and promote bone injury healing.
Background technology
The biological effect of pulse electromagnetic field (PEMF) is up-to-date in a bioelectromagnetics field, organism can make a generation new transmembrane potential (TEP) on the basis of cell membrane at original electrostatic potential under the effect of PEMF, its size and outfield relating to parameters are also with relating to parameters such as the kind of film, volume, sizes.The size of TEP, the mode of persistent period and generation thereof can directly influence the film activity of cell, the permeability of film, chromosomal aberration, the 26S Proteasome Structure and Function of cell changes, biological characteristicses such as propagation and heredity.
Effect low-yield, that low frequency electromagnetic field is rebuild bone formation, bone resorption and bone has been tending towards generally acknowledged.Its mechanism of action is as follows:
1, promotes the synthesis secretion and the osteogenesis of somatomedin
Various somatomedin have different biological activitys and effect, mainly comprise: mitogen activity, molten bone active and differentiation, chemotaxis play an important role in local skeletonization.PEMF mainly can promote the synthesis secretion of following somatomedin:
(1) insulin like growth factor (IGF) comprises IGF-I and IGF-II, has the mature osteoclast of stimulation functional activity, regulates bone resorption, participates in the function of bone remodeling.Lammens finds that the content of IGF-I in the PEMF stimulating group callus obviously increases in the osteotomy prolongation test of dog, knitting is faster than matched group.But Fitzsimmons etc. find PEMF in stimulating osteoblast propagation not only the induced osteogenesis cell discharge IGF-II, and can increase the number of IGF-II receptor on the cell membrane, both impel cell proliferation at combined effect.
(2) bone morphogenetic protein (BMP), the main biological action of BMP are to induce undifferentiated mesenchymal cell to be divided into cartilage and bone, i.e. induced osteogenesis effect.Bodamyali gives newborn rat skull osteoblast PEMF to be stimulated, and promotes transcribing of BMP mRNA when the result shows the PEMF promote osteogenesis.
(3) β-transforming growth factor (TGF-β) can stimulate the mesenchymal cell proliferation and differentiation, promotes skeletonization and chondroblast propagation, induces the synthetic of type i collagen, osteopontin (osteopontin) and osteonectin (opteonectin).TGF-β can also raise the expression of propagation specific gene PROM-1 in the osteoblast, thereby regulates and control osteoblastic propagation.
2, promote extracellular matrix synthetic, the inducing cell differentiation
PEMF is by adding strongly expressed type i collagen and type i collagen mRNA, and extensively the mediated cell epimatrix is synthetic.Lohmann etc. place 15Hz with people's skeletonization like cell MG63, and in the Helmholtz coil of 20 pulses/s, PEMF stimulates obviously strengthens osteoblast alkali phosphatase (ALP) activity; Synthetic and the Bone Gla protein of collagen increases TGF-β after 2 days
1Level increases, and shows that PEMF can be enhanced to the expression of osteocyte ALP, promotes the synthesis secretion of Bone Gla protein and collagen.
3, influence osteoblast Ca
2+Content
PEMF stimulates can cause Ca in the cell
2+Content increases, Ca
2+Increase and directly or to pass through to activate some protein kinases of calmodulin, CaM indirect activation, and then cause that the protein phosphorylation effect changes a series of signal path in the cell, stimulus signal is passed in the nuclear, cause the promotion cel l proliferation.Brighton is by thinking to the In vitro culture of osteocyte MC3T3-E1, and PEMF is by promoting Ca in the cell at cell culture in early days
2+Release increase Ca in the cell
2+Content, and be to increase Ca in the cell by activating calmodulin, CaM in the later stage
2+Content.
4, promote nitric oxide (NO) synthetic
PEMF stimulation can promotion nitric oxide (NO) is synthetic.NO is a kind of important bone signaling molecule, can mediate the influence of mechanical stimulus to the knitting process, moderate content, the NO energy stimulating osteoblast proliferation and differentiation that slowly discharges, and the ALP activity increases.Diniz etc. experimental results show that: PEMF stimulation can increasing NO synthesizes and PEMF stimulates the synthetic increase of following NO can mediate the proliferation and differentiation that skeletonization is a cell.
5, suppress the cell slit and connect communication
PEMF stimulates can suppress the connection communication (GJIC) of cell slit.GJIC is the intercellular a kind of information communication that is in contact with one another, and participates in the proliferation and differentiation of regulating cell.GJIC suppresses when normal structure regeneration and cell proliferation, and the PEMF effect has suppressed the function of GJIC, thereby promotes cell proliferation.The initial action point of PEMF and cell is at cell membrane, PEMF acts on the receptor on the cell membrane, cyclic adenosine monophosphate (cAMP) system in the active cell, then trigger a series of phosphorylation signals and amplify reaction, activating enzymes system successively again, activate bone or the reaction of chondrocyte generation special physiological by various enzymes then, promote cell proliferation and differentiation.
6, the different maturation period of osteoblast are exerted an influence
Diniz etc. have studied PEMF, and (15Hz is that the different maturation period cell proliferation (mensuration dna content) of MC3T3-E1, differentiation (mensuration alkaline phosphatase activities) and osteoid tissue form the situation that influences of (measuring the mineralising matrix areas) to osteoblast 0.7mT).The result shows: the pulse electromagnetic stimulation can produce different effects in osteoblastic different times, acts on osteoblasticly can quicken cell proliferation in early days, promotes cell differentiation and osteoid tissue to form, and the later stage can accelerated bone be organized mineralization process.
Utilizing the pulsed electromagnetic field therapy osteoporosis is to adopt high energy antiresonance low frequency variations pulse electromagnetic field to change this principle of human-body biological electric field, acts on osteocyte, promotes the propagation of cell mitogen and mature cell to treat osteoporosis.Because various pulse electromagnetic fields can make the field intensity of skeleton change, skeleton itself has a stable bio-electric field, in case be subjected to the stimulation of extraneous field, broken this bio-electric field, partial bio-electric field is changed, under the situation that energy and intensity can be controlled, growth, bone density improving and bone mass that can the accelerated bone tissue.Studies show that the osteoporosis of middle-aged and elderly people pilosity, can obtain good clinical effectiveness through pulsed electromagnetic field therapy.
In addition, pulse electromagnetic field is damaged at some congenital bone, arthrodesis failure, osteonecrosis (as femur bone bland necrosis), bone transplanting, interbody fusion, Sudeck atrophy and obstinate myositis, promote in the treatment of aspects such as upgrowth and development of children therapeutic effect is in various degree arranged all.
Mentioned a kind of method of non-intrusive electromagnetic field treatment osteoporosis among the previous Chinese patent CN1306869A that submits to of inventor herein, an electromagnetic field generator promptly is provided.Electromagnetic field generator is arranged near the intensive zone of the sharp site distribution of patient's susceptibility, produce an electromagnetic field that is used for the treatment of by electromagnetic field generator, make this electromagnetic field pass zone, the sharp position of susceptibility, changing the electricity and the chemical environment of general tissue, the growth that influence and revising is organized, repair and keep.Electromagnetic field puts in the human body such as conception vessel, meridians such as governor vessel, and centrality distributed areas, the sharp position of acupuncture point isosensitive not only can increase bone mineral content, improve bone density, and can significantly improve the microstructure of bone, improve its mechanical strength.
Ultrasound wave is a kind of mechanical wave, when propagating in vivo, by the interaction between them, can cause that biological intravital function or structure change, thereby cause a series of physiological effect.
Ultrasound wave can change biological cell in physical property ground, and this mechanical change finally causes the molecules and the biochemical variation of cell, thereby changes the biological function of cell.From the sound angle of mechanics, on the interface of fracture skeleton and muscle or skeleton and callus, a large amount of incident radiation energy are reflected, and this will cause having in physiological tissue tangible acoustic stress to change.Mechanism by the mental retardation pulse ultrasonic wave, the pressure that can cause in tissue is no more than three atmospheric pressure, each cell can bear very little pressure to be changed, this pressure deficient change is to cause cells injury, but can make cell produce the volume motion change, the pressure of this fine structure changes, and can play trickle massage effect.The difference of S. E. A. can flow by initiation sound mechanics, particularly is easy to produce this phenomenon in having a large amount of region of fluid.This pressure wave current acts on the irregular section of fracture, is mechanically stimulating fibroblast, chondroblast and osteoblastic propagation and differentiation.Ultrasonic wave energy changes the shape of cell, also can influence the liquid stream of cell periphery, thereby improve the nutrient microenvironment of cell.In addition, often be transformed into heat energy by the energy that living organism absorbed, this heat energy can cause that local temperature changes.Some enzyme (for example Collagenase) is very responsive to minimum variations in temperature, so ultrasound wave can be assisted some enzyme precursor reactants.
The external low-yield pulse ultrasonic wave of report (LIPUS) promotes that calcium ion combines with the chondrocyte that is breaking up, osteocyte, make the active raising of second message,second messenger, adenylate cyclase activity increases, and then impels the synthetic TGF-β of osteoblast to increase, and promotes union of fracture.Relevant expert found through experiments LIPUS and can impel early stage cartilage inner cell epimatrix proteic synthetic, thereby influences chondrocyte maturation and endochondral ossification, and then accelerates callus formation.It is synthetic that LIPUS not only increases albumen, and make fibroblast produce the type i collagen increase.Research prompting LIPUS also can be by the healing that promotes synthesizing of I, II Collagen Type VI in the increase callus to fracture.Some experimentatioies show the blood flow by LIPUS treatment can increasing fracture site, and the blood flow increase is the important step that LIPUS promotes union of fracture, increase consistent with callus formation and bone amount.Ultrasound wave can also be accelerated the reparation of soft tissue injury, increases the synthetic of collagen, makes arrangement of collagen fibers neat.
In a word, when ultrasound wave is propagated with high frequency acoustic stress waveshape in living organism, can regulator gene express, influence second message,second messenger's activity, quicken the healing of fracturing.Ultrasound wave is to the thermogenetic effect of human body, and expansible blood vessel strengthens blood circulation, quickens metabolism, eases the pain, and plays antiinflammatory, analgesic activity.
Narrated a kind of device that utilizes ultrasound wave to promote union of fracture among the Chinese patent CN1724093A, this device adopts a Single Chip Microcomputer (SCM) system to produce ultrasonic signal, arrive high frequency through modulators modulate again, amplify the driving transducer through high frequency power and produce the ultrasonic signal that is used for the treatment of.Described ultrasonic transmission device is arranged on close patient's painful area or fracture site has taken place, produce a ultrasound wave that is used for the treatment of by ultrasonic transmission device, make this ultrasonic irradiation patient sufferer place,, promote union of fracture to impel the callus liquid flow of local on every side.The healing that this device can quicken to fracture, but for the osteoporotic patient with bone fracture, because its bone density is less, bone mass is lower, and healing stage is longer, might cause bone wound once more.
The severe complications of osteoporosis is a fracture, its essential reason is the decline of bone strength, thereby present osteoporosis definition emphasizes that more bone strength is impaired, and bone strength mainly is that bone density (bone amount) (comprises the bone conversion with bone mass, bone mineralising, sclere etc.) concentrated expression.In patients with osteoporosis, because bone density is less, minor trauma just causes fracture easily, and the fracture back is difficult to healing.Easily sending out among the fracture patient group, existing the bone amount mostly and reduce and osteoporosis, resetting, in agglutination, also can cripetura and displacement occur because of bone of poor quality even initially can reach well.Secondly, some patient's fracture and injury is more serious, and the fracture end instability is depended merely on plaster fixation and is difficult to keep para-position.Quality of reduction is determined by the initial reduction with good of fracture, firm external fixation, the bone strength of fracture, the factors such as type of fracture after the union of fracture.In fracture healing process, along with the process of endochondral ossification, a large amount of calcareous and other ions are depleted in this process, will influence the bone density of skeleton on every side.
Ultrasonic therapy only is applicable to quickens the partial speed of fracture union of fracture patient, can not improve the osteoporosis of patient's general; And pulse electromagnetic field has better curative effect for the treatment osteoporosis, but for the considerable fracture patient that is caused by osteoporosis, the curative effect of accelerating union of bone fracture is also not obvious.
Summary of the invention
The purpose of this utility model is to provide a kind of non-intrusive electromagnetic field that utilizes to strengthen bone density promotes the osteoporotic bone injury healing in conjunction with low-yield pulse ultrasonic wave synthetic therapy equipment at above-mentioned deficiency.By electromagnetic field generator wholistic therapy osteoporosis, strengthen the human body bone density, change the electricity and the chemical environment of osseous tissue, influence and revise osseous tissue growth, repair and keep.Simultaneously,, promote the osseous tissue growth, shorten the bone injury healing time of causing, improve the cure rate of bone does not connect owing to osteoporosis by the low or fracture site of ultrasonic transmission device irradiation bone strength.Use above-mentioned rehabilitation from integral body to partial comprehensive therapy scheme treatment osteoporosis and promotion osteoporotic bone injury.
In addition, can change microcirculation in the body by non-intrusive electromagnetic field to the human body effect, relieve muscle spasms, ultrasound wave is to the mechanical effect of sufferer local irradiation, thermogenetic effect and physical and chemical effect can also play analgesic activity, effectively releasing osteoporosis pain and the pain of union of fracture phase.
This utility model device comprises power-supply system, the electromagnetic field treatment head and the ultrasonic therapy head that drive by the signal generator of described power-supply system power supply, by described signal generator.Wherein, signal generator (being electromagnetic field and ultrasonic signal generator) comprises by monolithic processor controlled electromagnetic field waveform generation module and ultrasound wave waveform generation module.
Described electromagnetic field waveform generation module comprises: D/A converter module, and the digital signal of the driving electromagnetic field waveform that singlechip CPU is sent converts analogue signal to; Pre-amplification circuit is isolated amplification with the analogue signal that converts to; Power amplifier will be isolated amplified analog signal through pre-amplification circuit and be amplified, and the power signal of power amplifier output is treated head through cable transmission to electromagnetic field.
Described ultrasound wave waveform generation module comprises: manipulator, and the high frequency small-signal and the modulation signal of the supersonic frequency that singlechip CPU is sent synthesize the required pulse signal; Pre-amplification circuit is isolated amplification with pulse signal; Power amplifier will be isolated amplified pulse signal through pre-amplification circuit and be amplified, and treat head through cable transmission to electromagnetic field.
Wherein, electromagnetic field treatment head comprises the inductance coil of the identical winding of many groups, each winding is separate and be arranged in parallel, be connected in turn, end of the same name is positioned at the same side, when passing to electric current, and the parallel distribution in magnetic field that each winding produces, stack mutually produces basic uniform electric magnetic field in treating the coil surrounding space on the same group.This electromagnetic field generator can send the electromagnetic field frequency that is used for the treatment of at 0～100Hz, and uniform magnetic field intensity 30 Gausses are with interior adjustable electromagnetic field.
Wherein, the ultrasonic therapy head comprises the transducer that is used to launch ultrasound wave and acts on the local skeleton of patient.This ultrasonic transmission device can be launched the ultrasonic frequency that is used for the treatment of at 0.8～3MHz, pulsewidth 10 μ s～1ms, and the repetition period, ultrasonic intensity was at 10～100mW/cm at 50Hz～5kHz
2
Wherein, power-supply system comprises the unidirectional current that is used for to the power supply of the digital circuit of signal generator, is used to drive the pre-amplification circuit unidirectional current, is used to drive the unidirectional current of the power amplifier of electromagnetic field coil and ultrasonic transducer.Above-mentioned each unidirectional current is+5V that the unidirectional current of powering to pre-amplification circuit is ± 12V to be ± 25V for the unidirectional current of electromagnetic field coil and ultrasonic transducer power amplifier power supply to the unidirectional current of digital circuit power supply.
This utility model device also comprises relevant input-output equipment and the alarm device that links to each other with single-chip microcomputer.Described input equipment can be a keyboard, is used to import various operational orders, the control signal generator; Described outut device can be a display screen as adopting liquid crystal display, is used to show various operational orders and relevant setting; Described alarm device can be audible alarm unit such as buzzer, can point out invalid operation or prompting treatment to finish.
This utility model also comprises and is used to control the microsystem that electromagnetic field and ultrasound wave produced, amplify, launch and made the two co-ordination.This utility model device integral body comprises main frame and shell, shows, input equipment that electromagnetic field and ultrasonic therapy head also comprise and be convenient to the Database Systems that doctor and patient are provided with therapeutic scheme and treatment CALCULATION OF PARAMETERS machine communication system and store the case therapeutic scheme.
Aspect of this utility model device, utilization non-intrusive electromagnetic field act on human body and strengthen bone density, and electromagnetic field generator is arranged near the intensive zone of the sharp site distribution of patient's susceptibility; Produce a Uniform Electromagnetic Field that is used for the treatment of by electromagnetic field generator, make this electromagnetic field pass the sharp position of patient's susceptibility, changing the electricity and the chemical environment of general tissue, the growth that influence and revising is organized, repair and keep.Electromagnetic field puts in the human body such as conception vessel, meridians such as governor vessel, and centrality distributed areas, the sharp position of acupuncture point isosensitive not only can increase bone mineral content, improve bone density, and can significantly improve the microstructure of bone, improve its mechanical strength.
This utility model device uses ultrasound wave to impel the osteoporotic bone injury to recover on the other hand, and ultrasonic transmission device is arranged on close patient's painful area or fracture site has taken place; Produce a pulse ultrasonic wave that is used for the treatment of by ultrasonic transmission device, make this ultrasonic irradiation patient sufferer place, to impel callus partial liquid flow on every side, make histiocyte produce the variation of volume and motion, and cell membrane formation shear stress, the film of striding that changes some ions and molecule turns round, and conduction of the signal in the active cell and related activity material is synthetic, quicken the process of endochondral ossification, thereby promoted union of fracture.
This utility model combines electromagnetic field and ultrasound wave, has formed a kind of composite therapeutic apparatus that is used for the treatment of osteoporosis and promotes the recovery of osteoporotic bone injury.Both can in seance, be used alternatingly, thereby avoid single biophysics to stimulate the fatigue effect that may cause to obtain better therapeutic effect, can in seance, use simultaneously again,, further increase curative effect two kinds of physical stimulation stacks.Shorten the osseous tissue growth cycle in to osteoporosis therapy, at because the fracture that osteoporosis causes, the healing that can quicken to fracture and improve healing quality reduces or the generation of prevent to heal slow or disunion.
The utlity model has following advantage:
1 electromagnetic field and the ultrasound wave that acts on human body is low-intensity, safely, have no side effect;
2 electromagnetic field and the ultrasound wave that act on human body are non-invasively treating, need not perform the operation, and can avoid the patient because the mental pressure that operation brings;
3 electromagnetic field effects reach the general physiological regulation in the sharp position of human feeling's property, alleviate patient's pain, improve bone density, strengthen bone strength;
4 ultrasound wave act on human body affected part or sore place, quicken the healing of osteoporotic fracture;
5 from integral body to the part, promotes the recovery of skeleton aspect morphology, biochemistry and biomechanics comprehensively.
Description of drawings
Fig. 1: the osteoporotic principle of device block diagram of electromagnetic field and ultrasound wave Comprehensive Treatment;
Fig. 2: system forms module map;
Fig. 3: set up example for one of this utility model signal generator;
Fig. 4 .1 a: embodiment of the present utility model: two-way inductance coil structure;
4.2: the two-way power amplifier schematic diagram that is used to drive this embodiment;
Fig. 5: the Collapsible mobile structure of electromagnetic field treatment coil;
Fig. 6: the synthetic and ultrasonic transmission device sketch map of ultrasonic signal;
Fig. 7 .1: the structural representation of ultrasonic therapy head;
7.2: the fixed structure sketch map of ultrasonic therapy head;
Among the figure, 1 binding post, 2 treatment heads, 3 grooves, 4 coupling glue filling slots, 5 binder connecting holes;
Fig. 8: guidance panel sketch map.
The specific embodiment
The utility model is described in further detail below in conjunction with accompanying drawing, but be not used for limiting scope of the present utility model.
Fig. 1 is a schematic diagram of device of the present utility model, the comprehensive therapy scheme that Single Chip Microcomputer (SCM) system is sent from computer by Ethernet interface acceptance, or by liquid crystal display on the host panel and button operation input therapeutic scheme, the electromagnetic field partial parameters is handled the digital signal that the back produces driving electromagnetic field waveform through singlechip CPU (below abbreviation CPU), after the D/A conversion, pass through the analogue signal isolating amplifier circuit (pre-amplification circuit) that photoelectrical coupler and amplifier are formed again, send into the power amplifier in-phase end and amplify, the power signal process cable transmission of power amplifier output is to field coil.When coil passes to electric current, promptly produce corresponding magnetic field in the space around.Driving electromagnetic field can be with sinusoidal wave, all kinds of effective waveforms such as impulse wave, and its frequency and intensity all can be provided with by host panel or host computer.
Partly be provided with the magnetic field induction module at field coil, this module is passed through signal processing by mistor bridge induced field intensity and changes of magnetic field, isolate and amplify, the A/D conversion feeds back to CPU, and CPU controls the output signal energy grade by analyzing feedback signal, thereby realizes closed loop control.
The ultrasound wave partial parameters is sent into ultrasonic signal generation module after CPU handles, the high frequency small-signal of the supersonic frequency that manipulator sends CPU and the pulse signal that modulation signal synthesizes required frequency range, sending into high frequency power amplifier after isolating amplification amplifies, export to ultrasonic transducer by radio frequency coaxial-cable, drive transducer and send corresponding ultrasonic signal.Driving hyperacoustic signal frequency, intensity and treatment time all can or insert host computer by the main frame TIP and be provided with.Simultaneously, the described ultrasonic transducer of this utility model is to have reversible transducer, can change the signal of telecommunication into ultrasonic signal, also can receive the echo ultrasonic signal, changes it into signal of telecommunication.Echo-signal feeds back to CPU by the echo receiving processing circuit, can detect the soft tissue thickness that ultrasonic transducer degree of coupling and ultrasound wave pass through, and CPU is by the discriminatory analysis echo-signal, thus control output signal energy grade.
Above-mentioned single-chip microcomputer, D/A converter, A/D converter, manipulator, pre-amplification circuit and power amplifier are integrated on the interior mainboard of main frame.
Fig. 2 is electromagnetic field and each module of ultrasound wave generation systems and composition diagram.The signal generator mainboard has two main output interfaces, is respectively applied for to insert electromagnetic field treatment head and ultrasonic therapy head.Mainboard also has and is used for the communication interface that incoming communication network and host computer carry out communication.On mainboard, also be connected to host service function keyboard, input-output equipment such as liquid crystal display.Power supply output direct current+5V, ± 12V and ± 25V.+ 5V, ± 12V is used for the power supplies such as digital circuit, pre-amplification circuit, keyboard Liquid Crystal Module and system radiating fan to signal generator.± 25V is used for driving electromagnetic field and the power supply of hyperacoustic power amplifier to signal generator.
Receive the therapeutic scheme of being imported by the correlated digital circuit and reached stop instruction, CPU sends the corresponding driving waveform digital signal, by the D/A conversion, amplify, carry out power amplification rear drive solenoid by OPA541 after the light-coupled isolation and produce and be provided with the pairing electromagnetic field of parameter.CPU sends corresponding ultrasound wave digital signal (high frequency small-signal) simultaneously, synthesize required high-frequency pulse signal by manipulator after, again through isolate amplifying and power amplification output driving ultrasonic transducer sends corresponding ultrasound wave.Mainboard is provided with clock control treatment time, and treatment is finished all signals of back and stopped emission, and mainboard is provided with the buzzer prompting treatment end of sounding automatically simultaneously.
In addition, the signal generator mainboard is provided with the ethernet communication module, system can by the RJ45 interface with have the computer communication of Ethernet card, computer can be provided with software setting, change treatment parameter by the treatment parameter, and with the signal generator host communication.Simultaneously, computer software has the background data base support, can consult patient's case, treatment record and treatment parameter.
Fig. 3 is a concrete establishment example, and CPU is that the MSP430 (16 8-digit microcontroller) of TI company also can be other high performance microcontrollers.
The ethernet communication part is made of treatment parameter and other instructions that CPU accepts keyboard or sends by the Ethernet host computer RTL8019 and RJ45 interface.
The electromagnetic field part:
CPU sends the digital signal that is used for electromagnetic field treatment waveform, DA5631 is converted to analogue signal through the D/A conversion chip, amplify through amplifier (LF356) filtering, behind light-coupled isolation (PC817) and the signal amplifier (LM741), amplify the back by power amplifier (OPA541) and form the waveform that drives the electromagnetic field coil and satisfy the treatment parameter.Power amplifier (OPA541) can be 2 the road or multichannel, and its feedback resistance adopts digital potentiometer, provides signal controlling by CPU, thereby regulates output waveform driving power size, to regulate magnetic field intensity.
Electromagnetic field treatment head is provided with the magnetic field induction module, and faradic current amplifies through isolating, and feeds back to CPU after the A/D conversion and handles.
The ultrasound wave part:
CPU sends the high frequency small-signal and the modulation signal of supersonic frequency, synthesize the required pulse signal through manipulator (74LS08 high speed and door), through preposition amplification (AD8684), optocoupler (PC957 high speed photo coupling) is isolated, and signal amplifies (AD8868) and the impulse ultrasound waveform that is used to drive ultrasonic therapeutic head is exported in power amplification (OP179) back.
Feedback fraction amplifies through isolating, and the echo phase discriminator feeds back to CPU to be handled.
Fig. 4 .1 is an embodiment of the present utility model: two-way inductance coil structure.Present embodiment will be organized inductance coil more and be divided into two-way, be convenient to adapt to split or accordion structure, also be convenient to the power that treatment needs to regulate two parts treatment head output electromagnetic field at the health different parts.
Fig. 4 .2 is for driving the two-way power amplifier circuit structure of this two-way inductance coil.This circuit adopts the two-way power amplifier structure, the feedback resistance of power amplifier adopts digital potentiometer, to regulate two-way output energy size respectively, the output of two groups of power amplifiers connects the two-way inductance coil respectively by cable, drives the two-way coil simultaneously and produces Uniform Electromagnetic Field by CPU control potentiometer resistance.This circuit has increased amplifying power and output accuracy, has reduced the caloric value of power amplifier, also makes things convenient for a little less than the electromagnetic field intensity of metering needle to the effect of health different parts simultaneously.For example: use electromagnetic field to patient's spinal column radiation treatment process in, can be set to 60% near lumbar portion coil groups field intensity, can be set to 40% near the coil groups field intensity of head and cervical region.
Fig. 5 is the Collapsible mobile structure of electromagnetic field treatment coil.Every group of coil is by the insulation shell encapsulated by structures, and coil windings is wrapped on the specific skeleton, and this specific skeleton can be embedded in the shell structure, and it is continuous by lead by the via hole of each housing that each organizes coil.The coil groups periphery is wrapped up by soft material, can be sewed up by materials such as canvas.Its edge interface place is used to insert cable and links to each other with main frame.This coil groups can fold, and conveniently is laid on bed and goes up or seat, is placed in the bag for ease of carrying to fold.
Synthetic and the ultrasonic transmission device sketch map of Fig. 6 ultrasonic signal.Send high frequency small-signal 1 and modulation signal 2 by CPU, synthesize required pulse ultrasound wave sequence 3, after light-coupled isolation, drive ultrasonic transducer by power amplifier output and send ultrasound wave by manipulator.Feedback signal feeds back to CPU and handles after light-coupled isolation and amplification.
Fig. 7 .2 is the retention system of ultrasonic therapy head, a ultrasonic therapy retention system is provided with the base of a band fixed groove 3, has binder connecting hole 5 on the base, be used to connect binder, bottom portion of groove and skin contact are provided with coupling glue filling slot 4, during treatment binder is bundled in the affected part, 2 (a Fig. 7 .1) screws in groove 3 with ultrasonic therapy, touches coupling glue until the treatment head.Treatment head is provided with a draw-in groove structure simultaneously, and when the treatment head all was rotated into the base stiff end, draw-in groove can tighten the treatment head to be made it to be difficult for loosening, has also determined the position that the treatment head is gone up ultrasonic transducer simultaneously.The ultrasonic transducer that the ultrasonic therapy head is had is the ultrasonic transducer that has the function of transmitting and receiving simultaneously, when the ultrasonic emitting test signal, receive inverse signal simultaneously and feed back to main frame and be used to detect ultrasound wave degree of coupling and patient's soft tissue thickness, thereby reach the purpose of closed loop control ultrasonic power.
Fig. 8 is the host service function panel, comprising the terminal that inserts electromagnetic field treatment head, inserts the terminal of ultrasonic therapy head.Liquid crystal display is used to show therapeutic scheme and adjustment of treatment parameter.Electromagnetic field is regulated part, is used to regulate electromagnetic field intensity, frequency, treatment time, begin treatment and time-out, and the selection of 5 kinds of therapeutic schemes.Ultrasound wave is regulated part and is used for the hyperacoustic intensity of adjustment of treatment, and frequency, begins and suspends at treatment time.Other part buttons are host power supply, begin/stop treatment, host reset, and numeral input button.The numeral importation is used to import the intensity percent that will regulate, digital parameters such as frequency and treatment time.Knob A is used for the digital parameters setting, and the increase that turns clockwise is rotated counterclockwise and reduces, and presses down affirmation.Knob B is used to regulate liquid crystal display brightness on the host panel.
Device of the present utility model is applied widely, both has been applicable to common sufferers of osteoporosis face treatment osteoporosis, is applicable to the patient who causes fracture because of osteoporosis again, helps it to recover fracture, and then treats its osteoporosis comprehensively.This utility model device works under the unified operation interface, and is convenient at the comprehensive therapeutic scheme of sufferers of osteoporosis face formulation individual character.In addition, electromagnetic field and ultrasonic generator are incorporated in the high-performance Single Chip Microcomputer (SCM) system, utilize the control software control, not only improved therapeutic effect but also reduced cost, dwindled volume.This utility model device promptly can be applicable to the big-and-middle-sized physiotherapy equipment of hospital, but also integration of compactization makes things convenient for family to use.
Claims (12)
1. the device of electromagnetic field and excusing from death ripple combination therapy osteoporosis, comprise power-supply system, it is characterized in that this device also comprises at least one electromagnetic field treatment head and the ultrasonic therapy head that drives by the signal generator of described power-supply system power supply, by signal generator.
2. electromagnetic field as claimed in claim 1 and the device of having children outside the state plan ripple combination therapy osteoporosis, it is characterized in that described signal generator comprises single-chip microcomputer and by monolithic processor controlled electromagnetic field waveform generation module and ultrasound wave waveform generation module, described electromagnetic field waveform generation module comprises:
D/A converter module, the digital signal of the driving electromagnetic field waveform that singlechip CPU is sent converts analogue signal to;
Pre-amplification circuit is isolated amplification with the analogue signal that converts to;
Power amplifier will be isolated amplified analog signal through pre-amplification circuit and be amplified, and the power signal of power amplifier output is treated head through cable transmission to electromagnetic field;
Described ultrasound wave waveform generation module comprises:
Manipulator, the high frequency small-signal and the modulation signal of the supersonic frequency that singlechip CPU is sent synthesize the required pulse signal;
Pre-amplification circuit is isolated amplification with pulse signal;
Power amplifier will be isolated amplified pulse signal through pre-amplification circuit and be amplified, and the process cable transmission is to the ultrasonic therapy head.
3. electromagnetic field as claimed in claim 1 and the device of having children outside the state plan ripple combination therapy osteoporosis is characterized in that described signal generator also has the computer PORT COM.
4. electromagnetic field as claimed in claim 1 and the device of having children outside the state plan ripple combination therapy osteoporosis is characterized in that described signal generator also has alarm device.
5. electromagnetic field as claimed in claim 1 and the device of having children outside the state plan ripple combination therapy osteoporosis, it is characterized in that this device also comprises the base that is used for fixing the ultrasonic therapy head, described base is provided with groove and binder, and bottom portion of groove and skin contact are provided with coupling glue filling slot.
6. electromagnetic field as claimed in claim 2 and the device of having children outside the state plan ripple combination therapy osteoporosis, it is characterized in that described electromagnetic field treatment head comprises many group field coils, partly be provided with the magnetic field induction module at field coil, this module is by mistor bridge induced field intensity and changes of magnetic field, pass through signal processing, isolate and amplify, the A/D conversion feeds back to singlechip CPU, and singlechip CPU is by analyzing feedback signal control output signal energy grade.
7. electromagnetic field as claimed in claim 2 and the device of having children outside the state plan ripple combination therapy osteoporosis, it is characterized in that described ultrasonic therapy head comprises ultrasonic transducer, described ultrasonic transducer can receive the echo ultrasonic signal, change it into signal of telecommunication, and feeding back to singlechip CPU by the echo receiving processing circuit, singlechip CPU is by analyzing echo-signal control output signal energy grade.
8. electromagnetic field as claimed in claim 2 and the device of having children outside the state plan ripple combination therapy osteoporosis, it is characterized in that this device also comprises input equipment and the display device that links to each other with signal generator, described input equipment sends to singlechip CPU by digital circuit with operational order.
9. electromagnetic field as claimed in claim 6 and the device of having children outside the state plan ripple combination therapy osteoporosis is characterized in that this device comprises two electromagnetic fields treatment heads that work alone.
10. electromagnetic field as claimed in claim 6 and the device of having children outside the state plan ripple combination therapy osteoporosis, it is characterized in that described plurality of electromagnetic field coil is the folding structure, every group of coil is by the insulation shell encapsulated by structures, coil windings is wrapped on the specific skeleton, this specific skeleton is embedded in the shell structure, and it is continuous by lead by the via hole of each housing that each organizes coil.
11. as each described electromagnetic field of claim 1～10 device with excusing from death ripple combination therapy osteoporosis, the electromagnetic field frequency that it is characterized in that electromagnetic field treatment head is at 0～100Hz, magnetic field intensity 0～30 Gauss.
12. as each the described electromagnetic field of claim 1～10 and the device of excusing from death ripple combination therapy osteoporosis, the ultrasonic frequency that it is characterized in that the ultrasonic therapy head is at 0.8～3MHz, pulsewidth 10 μ s～1ms, the repetition period, ultrasonic intensity was at 10～100mW/cm at 50Hz～5kHz
2
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| CNU2007201491947U CN201094810Y (en) | 2007-05-18 | 2007-05-18 | Electromagnetic field and ultrasound wave composite device for curing osteoporosis |
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| CNU2007201491947U CN201094810Y (en) | 2007-05-18 | 2007-05-18 | Electromagnetic field and ultrasound wave composite device for curing osteoporosis |
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| CN201094810Y true CN201094810Y (en) | 2008-08-06 |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102600547A (en) * | 2012-02-06 | 2012-07-25 | 广州赛莱拉生物科技有限公司 | Device and application for promoting transdermal absorption of stem cell growth factor covered by liposome |
| CN102793975A (en) * | 2012-06-12 | 2012-11-28 | 西安交通大学 | Electromagnetic field generating instrument for promoting bone healing and application |
| CN104548373A (en) * | 2015-01-01 | 2015-04-29 | 岳耀升 | Osteoporosis Therapy Apparatus |
| CN107789751A (en) * | 2017-11-06 | 2018-03-13 | 复旦大学 | A kind of ultrasonic two-dimensional array treatment band |
| CN108452445A (en) * | 2015-12-30 | 2018-08-28 | 夏周阳 | One kind being cured device based on ultrasonic therapy bone |
| CN109925180A (en) * | 2019-04-17 | 2019-06-25 | 太科航天智能康养技术(深圳)有限责任公司 | Wearable bone loss convalescence device |
| CN110960797A (en) * | 2019-12-31 | 2020-04-07 | 山东曼诺基因靶向技术有限公司 | Pulse electromagnetic field whole body treatment device |
| CN116251016A (en) * | 2023-05-10 | 2023-06-13 | 四川大学华西医院 | Treatment head device for treating osteoporosis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102600547A (en) * | 2012-02-06 | 2012-07-25 | 广州赛莱拉生物科技有限公司 | Device and application for promoting transdermal absorption of stem cell growth factor covered by liposome |
| CN102793975A (en) * | 2012-06-12 | 2012-11-28 | 西安交通大学 | Electromagnetic field generating instrument for promoting bone healing and application |
| CN104548373A (en) * | 2015-01-01 | 2015-04-29 | 岳耀升 | Osteoporosis Therapy Apparatus |
| CN104548373B (en) * | 2015-01-01 | 2017-05-03 | 四川明其医疗器械有限公司 | Osteoporosis Therapy Apparatus |
| CN106924881A (en) * | 2015-01-01 | 2017-07-07 | 充爱军 | A kind of safe and practical osteoporosis treatment instrument |
| CN108452445A (en) * | 2015-12-30 | 2018-08-28 | 夏周阳 | One kind being cured device based on ultrasonic therapy bone |
| CN108452445B (en) * | 2015-12-30 | 2019-10-18 | 刘铭东 | One kind being cured device based on ultrasonic therapy bone |
| CN107789751A (en) * | 2017-11-06 | 2018-03-13 | 复旦大学 | A kind of ultrasonic two-dimensional array treatment band |
| CN109925180A (en) * | 2019-04-17 | 2019-06-25 | 太科航天智能康养技术(深圳)有限责任公司 | Wearable bone loss convalescence device |
| CN110960797A (en) * | 2019-12-31 | 2020-04-07 | 山东曼诺基因靶向技术有限公司 | Pulse electromagnetic field whole body treatment device |
| CN116251016A (en) * | 2023-05-10 | 2023-06-13 | 四川大学华西医院 | Treatment head device for treating osteoporosis |
| CN116251016B (en) * | 2023-05-10 | 2023-08-01 | 四川大学华西医院 | A treatment head device for treating osteoporosis |
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Assignee: Beijing Xinshide Environmental Protection Technology Co., Ltd. Assignor: Cai Xiujun Contract record no.: 2010990000480 Denomination of utility model: Electromagnetic field and ultrasonic wave composite therapy device for osteoporosis Granted publication date: 20080806 License type: Exclusive License Record date: 20100630 |
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Granted publication date: 20080806 |