CN201026321Y - Artificial liver nephros support system - Google Patents
Artificial liver nephros support system Download PDFInfo
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- CN201026321Y CN201026321Y CNU2007201241481U CN200720124148U CN201026321Y CN 201026321 Y CN201026321 Y CN 201026321Y CN U2007201241481 U CNU2007201241481 U CN U2007201241481U CN 200720124148 U CN200720124148 U CN 200720124148U CN 201026321 Y CN201026321 Y CN 201026321Y
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- 210000004185 liver Anatomy 0.000 title claims abstract description 27
- 208000009928 nephrosis Diseases 0.000 title 1
- 239000008280 blood Substances 0.000 claims abstract description 99
- 210000004369 blood Anatomy 0.000 claims abstract description 97
- 210000003462 vein Anatomy 0.000 claims abstract description 37
- 230000002572 peristaltic effect Effects 0.000 claims abstract description 36
- 239000002699 waste material Substances 0.000 claims abstract description 21
- 210000003734 kidney Anatomy 0.000 claims abstract description 14
- 230000010412 perfusion Effects 0.000 claims abstract description 14
- 230000008676 import Effects 0.000 claims description 17
- 239000012530 fluid Substances 0.000 claims description 15
- 229960002897 heparin Drugs 0.000 claims description 9
- 229920000669 heparin Polymers 0.000 claims description 9
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims description 8
- 230000005856 abnormality Effects 0.000 claims description 6
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- 238000011282 treatment Methods 0.000 abstract description 15
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- 231100000835 liver failure Toxicity 0.000 abstract description 7
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- 238000001179 sorption measurement Methods 0.000 abstract description 4
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- 102000004169 proteins and genes Human genes 0.000 abstract description 2
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- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 description 10
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- PNNCWTXUWKENPE-UHFFFAOYSA-N [N].NC(N)=O Chemical compound [N].NC(N)=O PNNCWTXUWKENPE-UHFFFAOYSA-N 0.000 description 2
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- External Artificial Organs (AREA)
Abstract
The utility model discloses an artificial liver and kidney supporting system which is characterized in that the blood output pipe of people body is connected with an blood inlet of a pass filter through a blood pump and the an blood outlet of a pass filter is connected with the blood inlet of a plasma separator, the blood outlet of which is communicated with the inlet of the vein pot; the outlet of the vein pot is connected with the blood input pipe of people body; an upper interface out of the membrane of the pass filter passes through the waste liquid pipe and is connected with the waste liquid bag; the infiltration and solution liquid bag is connected in series with a heating device and then is divided into two channels: one channel is connected with the lower interface out of the membrane of the pass filter after passing through a second peristaltic pump; the other channel is connected with the inlet of the vein pot after passing through a third peristaltic pump; the lower interface out of the membrane of the plasma separator is connected with delivery pipe of the separated substance which is communicated with the inlet of the vein pot after passing through the fourth peristaltic pump and being connected in series with a perfusion device. The utility model can carry on a blood dialysis and filtration treatment and blood adsorption simultaneously, can effectively remove the water-solubility small molecular and the protein binding toxin in the patients body suffering liver failure, thereby raising survival rate of the patients suffering liver failure.
Description
Technical field
This utility model relates to a kind of armarium, in particular for removing the medical artifical system for supporting liver and kidney of intravital exogenous and endogenous poisonous substance, refuse or other harmful substance of liver renal failure patient.
Background technology
Liver renal failure is a modal mode among the multiple organ failure, MOF, and toxic substance is more in the liver renal failure blood samples of patients, and existing and albumin bound material (as bilirubin) has the medium and small molecule toxin of a large amount of water solublity again.Common blood purification method and toxin reset mode are more single, below make introductions all round:
Hemodialysis---utilize disperse and ultrafiltration principle that patient's blood, dialysis solution are introduced in the dialyser (artificial kidney) simultaneously.Blood and dialysis solution are reverse flow in the inside and outside both sides of dialyzer, solute concentration gradient, osmotic gradient and hydraulic pressure gradient by means of both sides inside and outside the film, reach the both sides concentration balance by dispersion, to remove human body intracellular metabolic refuse, the material that needs be can replenish simultaneously, electrolyte and acid base imbalance corrected.Hemodialysis can be removed intravital soluble small molecular toxin of liver renal failure patient (as flesh liver, the blood urea nitrogen that renal failure produces, the blood ammonia that liver failure produces etc.) and excessive moisture, but almost can not remove albumin bound toxin and middle macromole toxin.
Hemofiltration---be the filtering function of imitation human body glomerule, utilize barometric gradient, a kind of blood purification method that poisonous and harmful substance in the blood is excreted by the filter semipermeable membrane, hemofiltration can be removed the medium and small molecule toxin that liver renal failure produces, but a little less than the removing of dialogue protein binding toxin.
Hemoperfusion---utilize the absorption principle of strong adsorbent such as active carbon or resin, the blood lead body is directly contacted with adsorbent outward, more measure solute in the absorption blood, remove endogenous or exogenous poisonous substance in the blood, reach the purpose of blood purification, hemoperfusion is mainly removed the fat-soluble macromole toxin that liver renal failure produces, and micromolecule can not effectively be removed in the water solublity.
Plasmapheresis---be to utilize plasma separator that the plasma fraction in the blood is separated to abandon, mend fresh plasma simultaneously in addition, toxin in the blood is followed blood plasma to abandon and is removed, it is better that plasmapheresis is removed effect to the macromole toxin, but it is relatively poor that micromolecule in the water solublity is removed effect, imports outside fresh plasma so increased the treatment cost and brought out complication easily because of needs.
The albumin adsorption cleaning---adopt and transport albumin bound toxins in the blood at the film outer circulation albumin solution of filter, the outer albumin solution of film is removed bonded toxin through adsorber again, albumin solution after the purification repeats next circulation again, the albumin adsorption cleaning is mainly removed albumin bound toxin (as bilirubin a large amount of in the blood of human body in the liver failure etc.) and soluble small molecular toxin, limited in one's ability to the middle molecule toxins removing, and the albumin of outer loop has also increased the treatment cost.
The blood cleaning equipment treatment pattern that is used for the treatment of at present liver renal failure both at home and abroad is more single, often can only carry out independent liver failure Supporting Therapy or renal failure Supporting Therapy, and it is not thorough that they remove toxin.And the toxin of wanting to remove simultaneously liver renal failure often need clinically multiple devices simultaneously (or successively) carry out, inconvenient operation, the treatment cost is too high, and delays best occasion for the treatment easily because treatment time prolongs.
The utility model content
Technical problem to be solved in the utility model is to provide a kind of artifical system for supporting liver and kidney that can remove interior a large amount of medium and small molecule toxins of water solublity of liver renal failure patient body and albumin bound toxin simultaneously.
The technical solution of the utility model is as follows: a kind of artifical system for supporting liver and kidney, comprise main frame, operation control display floater and control circuit, its key is: the both sides at described main frame are installed filter and plasma separator respectively, the blood of human body outlet tube joins through the blood inlet of blood pump and filter, the blood outlet of this filter is connected with the blood inlet of plasma separator by flexible pipe for medical purpose, the blood outlet of plasma separator communicates by the import of pipeline with the vein kettle, is connected to the blood of human body input pipe in the outlet of vein kettle; The film of described filter is gone up interface outward and is connected with sewer pipe, and this sewer pipe joins through first peristaltic pump and waste fluid bag; Be provided with the isosmotic solution bag on the next door of described waste fluid bag, this isosmotic solution bag joins by the import of pipeline and heater, the pipeline that picks out from the outlet of heater is divided into two-way, one the tunnel outside the film of second peristaltic pump and described filter lower interface be connected, another Lu Jingdi three peristaltic pumps communicate with the import of described vein kettle; The outer lower interface of the film of plasma separator is connected with the separator carrier pipe, and this separator carrier pipe communicates with the import of described vein kettle behind the 4th peristaltic pump and the perfusion device of connecting.
Adopt above technical scheme, blood of human body is introduced filter and plasma separator by the blood of human body outlet tube under the effect of blood pump, enters then behind the vein kettle by the defeated the Huis' body of blood of human body input pipe, forms the extracorporeal circulation of blood loop; Liquid in the isosmotic solution bag contains Na
+, K
+, Ca
2+, Mg
2+, Cl
-, HCO
3 -Plasma, its electrolyte ingredient and concentration and normal plasma are close, and osmotic pressure (be about 280～300m0sm/L) with colloidal osmotic pressure approaching, so be called isosmotic solution.After this liquid heats through heater, a part enters human body through the vein kettle as displacement liquid under the effect of the 3rd peristaltic pump, another part carries out mass exchange as dialysis solution enters filter under the effect of second peristaltic pump the film outside with blood, waste liquid after the exchange (dehydrating amount that also comprises the human body needs, waste liquid=dialysis solution+displacement liquid+dehydrating amount) enter in the waste fluid bag under the effect of first peristaltic pump, dialysis solution and displacement liquid are constantly removed small-molecule substance etc. in the water solublity in the blood by this process.Plasma separator is isolated the plasma fraction material from blood under the effect of the 4th peristaltic pump, remove through the perfusion device to feed back to the vein kettle again behind the albumin bound toxin (as bilirubin etc.) and enter human body.
This utility model can carry out hemodialysis by transfusion filters, can effectively remove the micromolecule toxin (as flesh liver, blood urea nitrogen and blood ammonia etc.) that renal failure produces; Under the effect of transfusion filters, can also carry out the hemofiltration treatment, can effectively remove the middle macromole toxin (β-MG and parathyroid hormone etc.) that renal failure produces; Simultaneously, this utility model is isolated plasma fraction in the blood by plasma separator, through injecting the vein kettle behind the perfusion device, can effectively remove the albumin bound toxin that liver failure produces (as bilirubin etc.), and do not need to import fresh plasma and albumin circulation fluid, saved cost greatly.
Heater can make and enter blood or approaching with the temperature and the human body temperature of blood contact liq, has guaranteed the thermal balance in the therapeutic process, and has made the patient feel more comfortable.
Be connected to calparine pipe on the blood of human body outlet tube between above-mentioned filter and the blood pump, this calparine pipe is connected with the heparin delivery side of pump.Heparin pump is sustainable filling heparin (anticoagulant) in whole blood purification treatment process, to avoid the extracorporeally circulating blood blood coagulation.
Be connected to arm on the above-mentioned sewer pipe, this arm and first pressure monitor join, and the control circuit of described first pressure monitor is connected with operation control display floater by lead, and by operation control display floater display abnormality state.The film external pressure of first pressure monitor monitoring filter, and the abnormal conditions of film external pressure can being shown so that operator take appropriate measures, thereby has guaranteed that therapeutic process is safe and reliable.
Above-mentioned waste fluid bag and isosmotic solution bag are hung on the hook of first electronic scale and second electronic scale, and this first electronic scale is connected with the interior control circuit of second electronic scale and main frame.The waste liquid amount that first electronic scale control is come out from blood, the second electronic scale controlling liquid enters the amount in the blood, and finally keeps human body body weight balance or finish from human body and accurately dewater.
Above-mentioned vein kettle is fixed on the air monitor, and on the blood of human body input pipe that vein kettle outlet links to each other flow plug is housed, and described air monitor and flow plug are connected with control circuit in the main frame by lead respectively.Air monitor has monitored air to be passed through, or when occur leaking blood, flow plug occlude blood loop has allowed bubble or contaminated blood can not enter human body, to guarantee therapeutic process safety.
The import of above-mentioned vein kettle also is connected with second pressure monitor by pipeline, and the control circuit of this second pressure monitor is connected with operation control display floater by lead, and by operation control display floater display abnormality state.The pressure of second pressure monitor monitoring vein kettle, and the abnormal conditions of vein kettle pressure can being shown so that operator take appropriate measures, thereby has guaranteed the therapeutic process safety and reliability.
The film of above-mentioned plasma separator is gone up interface outward and is connected with the 3rd pressure monitor by pipeline, and the control circuit of the 3rd pressure monitor is connected with operation control display floater by lead, and by operation control display floater display abnormality state.The film external pressure of the 3rd pressure monitor monitoring plasma separator, and the abnormal conditions of film external pressure can being shown is so that operator take appropriate measures, with the security reliability of further raising therapeutic process.
The beneficial effects of the utility model are:
1, can carry out hemodiafiltration treatment and blood plasma absorption simultaneously, can both effectively remove, improve liver renal failure patient's survival rate micromolecule and albumin bound toxin in the water solublity in the liver renal failure patient body.
2, need not in addition to mend fresh plasma, greatly reduce the treatment cost, and effectively avoided the exogenous blood plasma that draws to mend complication into generation.
3, the hemodiafiltration treatment be can carry out separately, intravital middle small-molecule substance of acute and chronic renal failure patient and redundant moisture fully removed.
4, Molecular Adsorption recirculation treatment (MARS) or albumin purification treatment (CAPS) continuously can be carried out separately, intravital albumin bound toxin of liver failure patient and soluble small molecular toxin (as blood ammonia etc.) can be fully removed.
5, therapeutic scheme is various, almost can both carry out corresponding blood purification treatment to any single organ failure or multiple organ failure, MOF.
6, the complete machine monitoring function is comprehensive, reliable, automaticity height, therapeutic process safety, operability height.
Description of drawings
Fig. 1 is a structural representation of the present utility model.
Among the figure: the 1-main frame; 2-operation control display floater; The 3-filter; The 4-plasma separator; 5-blood of human body outlet tube; The 6-blood pump; The 7-flexible pipe for medical purpose; 8-vein kettle; 9-blood of human body input pipe; The 10-sewer pipe; 11-first peristaltic pump; The 12-waste fluid bag; 13-isosmotic solution bag; The 14-heater; 15-second peristaltic pump; 16-the 3rd peristaltic pump; 17-separator carrier pipe; 18-the 4th peristaltic pump; 19-perfusion device; The 20-calparine pipe; The 21-heparin pump; 22-first electronic scale; 23-second electronic scale; The 24-air monitor; 25-second pressure monitor; The 26-flow plug; 27-the 3rd pressure monitor; The 28-side lever; 29-first filter folder; 30-second filter folder; 31 perfusion devices folder; 32-first pressure monitor.
The specific embodiment
The utility model is described in further detail below in conjunction with drawings and Examples:
As shown in Figure 1, this utility model is made up of body, extracorporeal circulation of blood loop, dialysis fluid circuit, fluid infusion loop, blood plasma absorption loop and operation control system.Body comprises parts such as main frame 1, side lever 28, first filter folder, 29, second filter folder 30 and perfusion device folder 31, and side lever 28 is arranged on the left side of main frame 1, and by first filter folder 29 transfusion filters 3 is installed; Plasma separator 4 is positioned at the right side of main frame 1, and fixing with main frame 1 by second filter folder 30.Two the perfusion devices 19 that are arranged side by side at the middle part in main frame 1 front, each perfusion device 19 is fixing by perfusion device folder 31.Be provided with first electronic scale 22 in the just basifacial left side of main frame 1, the right side is provided with second electronic scale 23, wherein hang with on the hook of first electronic scale 22 on the hook of waste fluid bag 12, the second electronic scales 23 and hang with isosmotic solution bag 13.
As can be known from Fig. 1, the extracorporeal circulation of blood loop by on blood of human body outlet tube 5, blood pump 6, filter 3, plasma separator 4, vein kettle 8, the air monitor 24, flow plug 26 and blood of human body input pipe 9 etc. form, wherein blood of human body outlet tube 5 pile warp blood pumps 6 backs join with the blood inlet at filter 3 tops, blood flow in the blood of human body outlet tube 5 provides power by blood pump 6, be connected to calparine pipe 20 on the blood of human body outlet tube 5 between filter 3 and the blood pump 6, this calparine pipe 20 is connected with the outlet of heparin pump 21.The blood outlet of filter 3 bottoms is connected with the blood inlet at plasma separator 4 tops by flexible pipe for medical purpose 7, the blood outlet of plasma separator 4 bottoms communicates by the import of pipeline with vein kettle 8, this vein kettle 8 is fixed on the air monitor 24, the import of vein kettle 8 also is connected with second pressure monitor 25 by pipeline, in the outlet of vein kettle 8 bottoms, be connected to blood of human body input pipe 9, flow plug 26 is housed on the blood of human body input pipe 9.
From Fig. 1 also as can be known, dialysis fluid circuit is made up of isosmotic solution bag 13, heater 14, second peristaltic pump 15, filter 3, sewer pipe 10, first peristaltic pump 11 and waste fluid bag 12 etc., wherein isosmotic solution bag 13 joins by the import of pipeline and heater 14, heater 14 is installed in the below of main frame 1 right side plasma separator 4, the pipeline that picks out from the outlet of this heater 14 is divided into two-way, wherein article one branch road pile warp second peristaltic pump 15 backs are connected with the outer lower interface of the film of described filter 3, and flowing of dialysis solution provides power by second peristaltic pump 15 in this pipeline.The film of described filter 3 is gone up interface outward and is connected with sewer pipe 10, these sewer pipe 10 pile warps first peristaltic pump 11 backs join with waste fluid bag 12, flowing of waste liquid provides power by first peristaltic pump 11 in the sewer pipe 10, and is connected to arm on sewer pipe 10, and this arm and first pressure monitor 32 join.
From Fig. 1 also as can be known, the fluid infusion loop is made up of isosmotic solution bag 13, heater 14, the 3rd peristaltic pump 16 and vein kettle 8 etc., wherein behind second branch road pile warp the 3rd peristaltic pump 16 that picks out from the outlet of heater 14, communicate with the import of described vein kettle 8, flowing of displacement liquid provides power by the 3rd peristaltic pump 16 in this pipeline.
From Fig. 1 also as can be known, blood plasma absorption loop is made up of plasma separator 4, separator carrier pipe 17, the 4th peristaltic pump 18, perfusion device 19 and vein kettle 8 etc., wherein the outer lower interface of the film of plasma separator 4 connects separator carrier pipe 17, behind this separator carrier pipe 17 pile warps the 4th peristaltic pump 18 and two the perfusion devices 19 of connecting successively, communicate with the import of described vein kettle 8, flowing of liquid provides power by the 4th peristaltic pump 18 in the separator carrier pipe 17.The film of described plasma separator 4 is gone up interface outward and is connected with the 3rd pressure monitor 27 by pipeline.
As shown in Figure 1, the top in main frame 1 front is provided with operation control display floater 2, this operation control display floater 2 is electrically connected with first electronic scale 22, second electronic scale 23, heater 14, flow plug 26, air monitor 24, first pressure monitor 32, second pressure monitor 25 and the 3rd pressure monitor 27 respectively by the control circuit in the main frame 1, and the liquid crystal display of controlling on the display floater 2 by operation carries out the state demonstration, the formation operation control system.On operation control display floater 2, be distributed with and each monitor corresponding key switch, can conveniently realize safety monitoring and the real-time monitoring of enforcement the entire machine operation.
In this utility model, independent parts such as filter, plasma separator, blood pump, vein kettle, peristaltic pump, heater, perfusion device, heparin pump, electronic scale, flow plug and each monitor are prior art, and its structure and operation principle are not given unnecessary details at this.
Work process of the present utility model is as follows:
When replacement therapy (be used for Liver and kidney simultaneously depleted) as shown in Figure 1, human body artery blood is introduced the transfusion filters 3 from blood of human body outlet tube 5 under the effect of blood pump 6, flow into plasma separator 4 through flexible pipe for medical purpose 7 then, enter vein kettle 8 backs by blood of human body input pipe 9 defeated the Huis' vena systemica blood vessels by pipeline again, form the extracorporeal circulation of blood loop.Air monitor 24 has monitored air and has passed through then flow plug 26 meeting occlude bloods; Heparin pump 21 continues to inject heparin in the exit of blood pump 6 and prevents the extracorporeally circulating blood blood coagulation.After liquid in the isosmotic solution bag 13 heated through heater 14, a part was mended in vein kettle 8 by pipeline as displacement liquid under the effect of the 3rd peristaltic pump 16 and is entered human body; Another part enters the film outside of transfusion filters 3 by pipeline under the effect of second peristaltic pump 15 as dialysis solution, and carry out mass exchange with blood, waste liquid after the exchange (dehydrating amount that also comprises the human body needs, waste liquid=dialysis solution+displacement liquid+dehydrating amount) enter waste fluid bag 12 by sewer pipe 10 under the effect of first peristaltic pump 11, dialysis solution and displacement liquid are constantly removed small-molecule substance etc. in the water solublity in the blood by this process.4 of plasma separators are isolated the plasma fraction material by separator carrier pipe 17 from blood under the effect of the 4th peristaltic pump 18, remove through two perfusion devices 19 to feed back to vein kettle 8 again behind the noxious substances (as bilirubin etc.) and enter human body.First pressure monitor 32, second pressure monitor 25 and the 3rd pressure monitor 27 are monitored the pressure anomaly situation in each loop simultaneously in the whole service process, to guarantee running safety, reliable; First electronic scale 22 and second electronic scale 23 guarantee dialysis liquid measure, displacement liquid measure and waste liquid amount turnover balance under the control of circuit, and finish on request from human body and dewater.
Claims (7)
1. an artifical system for supporting liver and kidney comprises main frame (1), operation control display floater (2) and control circuit, it is characterized in that:
A, filter (3) and plasma separator (4) are installed respectively in the both sides of described main frame (1), blood of human body outlet tube (5) joins through the blood inlet of blood pump (6) with filter (3), the blood outlet of this filter (3) is connected with the blood inlet of plasma separator (4) by flexible pipe for medical purpose (7), the blood outlet of plasma separator (4) communicates by the import of pipeline with vein kettle (8), is connected to blood of human body input pipe (9) in the outlet of vein kettle (8);
The film of B, described filter (3) is gone up interface outward and is connected with sewer pipe (10), and this sewer pipe (10) joins through first peristaltic pump (11) and waste fluid bag (12);
C, be provided with isosmotic solution bag (13) on the next door of described waste fluid bag (12), this isosmotic solution bag (13) joins by the import of pipeline and heater (14), the pipeline that picks out from the outlet of heater (14) is divided into two-way, one the tunnel outside the film of second peristaltic pump (15) and described filter (3) lower interface be connected, another Lu Jingdi three peristaltic pumps (16) communicate with the import of described vein kettle (8);
The outer lower interface of the film of D, plasma separator (4) is connected with separator carrier pipe (17), and this separator carrier pipe (17) communicates with the import of described vein kettle (8) behind the 4th peristaltic pump (18) and the perfusion device (19) of connecting.
2. artifical system for supporting liver and kidney according to claim 1 is characterized in that: be connected to calparine pipe (20) on the blood of human body outlet tube (5) between described filter (3) and the blood pump (6), this calparine pipe (20) is connected with the outlet of heparin pump (21).
3. artifical system for supporting liver and kidney according to claim 1, it is characterized in that: described sewer pipe is connected to arm on (10), this arm and first pressure monitor (32) join, the control circuit of described first pressure monitor (32) is connected with operation control display floater (2) by lead, and by operation control display floater (2) display abnormality state.
4. according to claim 1 or 3 described artifical system for supporting liver and kidney, it is characterized in that: described waste fluid bag (12) and isosmotic solution bag (13) are hung on the hook of first electronic scale (22) and second electronic scale (23), and this first electronic scale (22) is connected with the interior control circuit of second electronic scale (23) and main frame (1).
5. artifical system for supporting liver and kidney according to claim 1, it is characterized in that: described vein kettle (8) is fixed on the air monitor (24), with on the blood of human body input pipe (9) that vein kettle (8) outlet links to each other flow plug (26) is housed, described air monitor (24) and flow plug (26) are connected by the interior control circuit of lead and main frame (1) respectively.
6. artifical system for supporting liver and kidney according to claim 1 or 5, it is characterized in that: the import of described vein kettle (8) also is connected with second pressure monitor (25) by pipeline, the control circuit of this second pressure monitor (25) is connected with operation control display floater (2) by lead, and by operation control display floater (2) display abnormality state.
7. artifical system for supporting liver and kidney according to claim 1, it is characterized in that: the film of described plasma separator (4) is gone up interface outward and is connected with the 3rd pressure monitor (27) by pipeline, the control circuit of the 3rd pressure monitor (27) is connected with operation control display floater (2) by lead, and by operation control display floater (2) display abnormality state.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007201241481U CN201026321Y (en) | 2007-04-28 | 2007-04-28 | Artificial liver nephros support system |
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| Application Number | Priority Date | Filing Date | Title |
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| CNU2007201241481U CN201026321Y (en) | 2007-04-28 | 2007-04-28 | Artificial liver nephros support system |
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| CN201026321Y true CN201026321Y (en) | 2008-02-27 |
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| CNU2007201241481U Expired - Lifetime CN201026321Y (en) | 2007-04-28 | 2007-04-28 | Artificial liver nephros support system |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100493633C (en) * | 2007-04-27 | 2009-06-03 | 高光勇 | Artificial system for supporting liver and kidney |
| CN102458503A (en) * | 2009-06-09 | 2012-05-16 | 德国弗雷泽纽斯医疗保健股份有限公司 | Method and device for monitoring a fluid system of an extracorporeal blood treatment apparatus |
| CN102641526A (en) * | 2012-05-16 | 2012-08-22 | 重庆山外山科技有限公司 | Bedside continuous hemodialysis filtration device |
| CN104324429A (en) * | 2014-10-22 | 2015-02-04 | 珠海健帆生物科技股份有限公司 | Heparinization simplified pre-flushing method for perfusion device |
| CN104394899A (en) * | 2012-12-20 | 2015-03-04 | 甘布罗伦迪亚肾脏产品公司 | Blood kit components connection and detection |
| CN104971391A (en) * | 2015-06-19 | 2015-10-14 | 南方医科大学珠江医院 | Novel combined type liver and kidney support system CRRT mode tube |
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| CN108310503A (en) * | 2018-02-08 | 2018-07-24 | 中南大学湘雅二医院 | A kind of Almightiness type plasma purification system based on centrifugal separation plasma method |
| CN108430529A (en) * | 2015-06-15 | 2018-08-21 | 生命治疗有限公司 | system and method for extracorporeal blood treatment |
| CN113384767A (en) * | 2021-06-08 | 2021-09-14 | 汕头大学医学院第一附属医院 | Portable blood purification device |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100493633C (en) * | 2007-04-27 | 2009-06-03 | 高光勇 | Artificial system for supporting liver and kidney |
| CN102458503A (en) * | 2009-06-09 | 2012-05-16 | 德国弗雷泽纽斯医疗保健股份有限公司 | Method and device for monitoring a fluid system of an extracorporeal blood treatment apparatus |
| CN102458503B (en) * | 2009-06-09 | 2015-07-15 | 德国弗雷泽纽斯医疗保健股份有限公司 | Method and device for monitoring a fluid system of an extracorporeal blood treatment device |
| CN102641526A (en) * | 2012-05-16 | 2012-08-22 | 重庆山外山科技有限公司 | Bedside continuous hemodialysis filtration device |
| CN104394899A (en) * | 2012-12-20 | 2015-03-04 | 甘布罗伦迪亚肾脏产品公司 | Blood kit components connection and detection |
| CN104324429A (en) * | 2014-10-22 | 2015-02-04 | 珠海健帆生物科技股份有限公司 | Heparinization simplified pre-flushing method for perfusion device |
| CN108430529A (en) * | 2015-06-15 | 2018-08-21 | 生命治疗有限公司 | system and method for extracorporeal blood treatment |
| CN104971391A (en) * | 2015-06-19 | 2015-10-14 | 南方医科大学珠江医院 | Novel combined type liver and kidney support system CRRT mode tube |
| CN105879138A (en) * | 2016-06-11 | 2016-08-24 | 赵晓玲 | Extracorporeal circulation pipeline of plasma exchange device capable of switching blood separators |
| CN105879138B (en) * | 2016-06-11 | 2018-12-28 | 赵晓玲 | The plasmapheresis device extracorporeal circulation pipeline of changeable blood separator |
| CN108310503A (en) * | 2018-02-08 | 2018-07-24 | 中南大学湘雅二医院 | A kind of Almightiness type plasma purification system based on centrifugal separation plasma method |
| CN113384767A (en) * | 2021-06-08 | 2021-09-14 | 汕头大学医学院第一附属医院 | Portable blood purification device |
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