CN201015590Y - Bloodstream storing mark real time continuous measurement system - Google Patents
Bloodstream storing mark real time continuous measurement system Download PDFInfo
- Publication number
- CN201015590Y CN201015590Y CNU2007200788937U CN200720078893U CN201015590Y CN 201015590 Y CN201015590 Y CN 201015590Y CN U2007200788937 U CNU2007200788937 U CN U2007200788937U CN 200720078893 U CN200720078893 U CN 200720078893U CN 201015590 Y CN201015590 Y CN 201015590Y
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- ffr
- blood pressure
- real time
- time continuous
- blood flow
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- 238000005259 measurement Methods 0.000 title abstract description 7
- 230000036772 blood pressure Effects 0.000 claims abstract description 19
- 238000012545 processing Methods 0.000 claims abstract description 7
- 238000006243 chemical reaction Methods 0.000 claims abstract description 4
- 230000017531 blood circulation Effects 0.000 claims description 20
- 238000000034 method Methods 0.000 claims description 8
- 230000000250 revascularization Effects 0.000 abstract description 2
- 238000012544 monitoring process Methods 0.000 abstract 1
- 210000004351 coronary vessel Anatomy 0.000 description 10
- 208000031481 Pathologic Constriction Diseases 0.000 description 9
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 6
- 208000037804 stenosis Diseases 0.000 description 5
- 230000036262 stenosis Effects 0.000 description 5
- 238000002608 intravascular ultrasound Methods 0.000 description 4
- 231100000915 pathological change Toxicity 0.000 description 4
- 230000036285 pathological change Effects 0.000 description 4
- 239000002126 C01EB10 - Adenosine Substances 0.000 description 3
- 229960005305 adenosine Drugs 0.000 description 3
- 230000004872 arterial blood pressure Effects 0.000 description 3
- 206010020565 Hyperaemia Diseases 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 210000004165 myocardium Anatomy 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 230000003321 amplification Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000000004 hemodynamic effect Effects 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 230000002107 myocardial effect Effects 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 238000004451 qualitative analysis Methods 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 208000037803 restenosis Diseases 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
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- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Abstract
The utility model discloses a fractional flow reserve(FFR) real time continuous measurement system comprising a blood pressure sensor, a blood pressure guide wire, a filter circuit connected with the blood pressure sensor and the blood pressure guide wire in sequence, an analog to digital conversion circuit, a digital signal processing chip, a CPU processing chip and an output equipment. The utility model is capable of real time continuously measuring FFR, automatically calculating FFR value, real time display, monitoring and promptly and accurately capturing data. In medical treatment, reasonably selecting revascularization under guidance of FFR value can improve cost benefit ratio.
Description
Technical field
This utility model relates to the fractional equipment of blood flow reserve of measuring, promptly measure and have maximum blood flow of cardiac muscle when narrow and the no ratio of theoretical maximum blood flow when narrow, obtain real-time blood flow reserve mark after the parameter processing of native system by pressure transducer and blood pressure seal wire conjunction measuring.
Background technology
Blood flow reserve mark (FFR) is defined as and has maximum blood flow of narrow time cardiac muscle and the no ratio of the maximum blood flow of theory when narrow.Coronary artery pressure is directly proportional with blood flow under maximum congestive state, and remote pressure in the time of can be by coronary stricture and the remote pressure that does not have in theory when narrow calculate FFR.The resistance of normal coronary is very little under maximum congestive state, and the pressure of coronary artery far-end and near-end equates.Therefore, there is the coronary artery of pathological changes, can measuring the proximal coronal arterial pressure by guiding catheter and substitute no coronary artery remote pressure when narrow.That is to say that the average pressure of coronary artery near-end can calculate FFR when measuring coronary stricture far-end and maximum hyperemia respectively by coronary artery pressure seal wire and guiding catheter.
The mode of the calculating FFR that adopts is at present: general recommendations adopts no side opening guiding catheter to measure FFR, earlier seal wire is delivered to the pathological changes near-end, records pressure value, then seal wire is delivered to the pathological changes far-end, records pressure value, again manual calculations FFR value.Injection adenosine in the arteria coronaria, the pressure of employing manual mode continuous record guiding catheter (near-end) and pick off (far-end) can record FFR.Use more heavy dose of adenosine subsequently, repeat above operation and record true FFR to reach maximum hyperemia.After measurement finishes seal wire is recalled the guiding catheter head end, confirm whether both pressure mate and have or not baseline drift etc.The manual intervention that this action need is a lot.
Summary of the invention
The purpose of this utility model is: provide a kind of and can real-time continuous measure the fractional system of blood flow reserve.
The technical solution of the utility model is:
A kind of blood flow reserve mark real-time continuous measuring system is characterized in that this system comprises pressure transducer and blood pressure seal wire, with the two filter circuit that is connected successively, analog to digital conversion circuit, digital signal processing chip, CPU process chip and outut device.
Above-mentioned outut device can be selected for use and show outut device and/or print out equipment.
The beneficial effects of the utility model are: can real-time continuous measure FFR, calculate the value of FFR automatically, show in real time, monitor, obtain data in time, accurately.In medical procedure,, under the guidance of FFR etc., reasonably select myocardial revascularization, can improve the cost effectiveness ratio because bracket for eluting medicament costs an arm and a leg.Measuring system of the present utility model allows former qualitative analysis become quantitative analysis, whether must lay support in order to decision.For example: for the patient of FFR＞0.75, postpone and lay the support safe and feasible, the patient of FFR＜0.75 then needs to lay support.Simultaneously, FFR can be used to estimate the result of balloon expandable.Studies show that if FFR＞0.90, its 1 year and 2 years intervention rates once more are respectively 12% and 15% behind the balloon expandable; If FFR≤0.90, then 1 year and 2 years restenosis rate are respectively 28% and 30%.Whether FFR can also be used to estimate support and discharge desirable.Studies show that the patient IVUS that support is placed back FFR＞0.94～0.96 shows that support discharges well.
Description of drawings
Fig. 1 is this utility model blood flow reserve mark real-time continuous measuring principle of measurement system block diagram;
Fig. 2 is the sketch map of probe placement in heart of this utility model blood flow reserve mark real-time continuous measuring system;
Fig. 3 is the local amplification view that probe shown in Figure 2 is placed on the coronary stricture place.
Wherein, Reference numeral: 20 is pressure transducer,, 21 is the blood pressure seal wire, and 22 is the blood vessel of stenosis, and 23,24 is atherosis of blood vessel, and 25,26,27 is coronary artery, 28 is narrow location.
The specific embodiment
Below in conjunction with drawings and Examples this utility model is further specified.
Specific embodiment of the utility model, as shown in Figure 1, annexation between the each several part of blood flow reserve mark real-time continuous measuring system, this system comprises pressure transducer and blood pressure seal wire, with the two filter circuit that is connected successively, analog to digital conversion circuit, digital signal processing chip, CPU process chip and display.
The blood flow reserve mark real-time continuous measuring system operational mode of present embodiment is as follows:
As Fig. 1, blood pressure signal is sent to filter circuit by pressure transducer 20 and blood pressure seal wire 21, change through AD again, handle with digital signal processing chip (DSP), again by DSP and the communication of CPU process chip, data are delivered among the CPU handle, calculate mean pressure M0 and M1 that pressure transducer 20 and blood pressure seal wire 21 record then respectively, formula:
M＝S÷3+D×2÷3
Wherein S is a maximal pressure, and D is a minimal pressure.
Then according to formula
FFR＝M1÷M0
Calculate the value of FFR.
According to FFR value of calculating and primary blood pressure waveform data, deliver to the demonstration outut device and show.Print if desired, reach printer prints.
When operation, as shown in Figures 2 and 3, pressure transducer 20 is placed on the near-end of coronary artery 22 stenosis 23, think not stenosis herein, blood pressure seal wire 21 continues inward deeply along coronary artery, the variation of the value that this moment can real-time monitored FFR, when coronary artery does not have when narrow, its FFR=1.0, when FFR＜0.75, this moment, the blood pressure seal wire was at the far-end at coronary stricture place.Behind the injection adenosine, the blood pressure seal wire 21 that can move around is in order to the variation of real-time monitored FFR value in the arteria coronaria.Use native system, avoided the doctor to move back and forth the blood pressure seal wire during operation, increase operating difficulty, time, the measurement of blood pressure difference is calculated accurately, in time by CPU control, and variation that can Real Time Observation FFR value, exports the situation that blood pressure waveform is used to judge the patient.
Use the comparison of blood flow reserve fraction measurement moderate stenosis conduit room's evaluation methodology and other measuring methods
| Method | Absolute normal value | Critical values of anomalies | Be used for many pathological changes | Not influenced by microcirculation | Be not subjected to hemodynamic effects |
| CFR | Do not have | ～2.0 | Energy | Not | Be not |
| rCFR | (1.0) are arranged | ～0.65 | Can not | Be | Be not |
| FFR | (1.0) are arranged | 0.75 | Energy | Be | Be |
| IVUS | Do not have | MLA3～4mm 2 | Energy | Be | Be |
Annotate:
The minimum tube chamber cross-sectional area of MLA;
The CFR coronary flow reserve;
The relative CFR index of rCFR;
The IVUS intravascular ultrasound.
As seen from the above table, adopt blood flow reserve fraction measurement moderate stenosis conduit room to estimate and to obtain more efficiently data,, can judge patient's state in real time accurately in conjunction with equipment of the present utility model.
Claims (3)
1. a blood flow reserve mark real-time continuous measuring system is characterized in that this system comprises pressure transducer and blood pressure seal wire, with the two filter circuit that is connected successively, analog to digital conversion circuit, digital signal processing chip, CPU process chip and outut device.
2. blood flow reserve mark real-time continuous measuring system according to claim 1 is characterized in that, outut device is for showing outut device.
3. blood flow reserve mark real-time continuous measuring system according to claim 1 is characterized in that outut device is a print out equipment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007200788937U CN201015590Y (en) | 2007-03-28 | 2007-03-28 | Bloodstream storing mark real time continuous measurement system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007200788937U CN201015590Y (en) | 2007-03-28 | 2007-03-28 | Bloodstream storing mark real time continuous measurement system |
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| Publication Number | Publication Date |
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| CN201015590Y true CN201015590Y (en) | 2008-02-06 |
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| CNU2007200788937U Expired - Lifetime CN201015590Y (en) | 2007-03-28 | 2007-03-28 | Bloodstream storing mark real time continuous measurement system |
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Effective date of registration: 20100813 Address after: Wuhou Science Park Vuko East three road, hi tech Industrial Development Zone, Chengdu city of Sichuan Province, No. 5 610000 Patentee after: Sichuan Jinjiang Electronic Science and Technology Co., Ltd. Address before: 610000 Sichuan city of Chengdu province Wuhou District Wuhou Science Park Vuko East Three Road No. 5 Patentee before: Li Chuya |
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Effective date of registration: 20120727 Address after: 610000 Sichuan city of Chengdu province Wuhou District Wuhou Science Park Vuko East Three Road No. 5 Patentee after: Li Chuwen Address before: Wuhou Science Park Vuko East three road, hi tech Industrial Development Zone, Chengdu city of Sichuan Province, No. 5 610000 Patentee before: Sichuan Jinjiang Electronic Science and Technology Co., Ltd. |
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Owner name: SICHUAN JINJIANG ELECTRONIC SCIENCE AND TECHNOLOGY Free format text: FORMER OWNER: LI CHUWEN Effective date: 20121017 |
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Effective date of registration: 20121017 Address after: Wuhou Science Park Vuko East three road, hi tech Industrial Development Zone, Chengdu city of Sichuan Province, No. 5 610000 Patentee after: Sichuan Jinjiang Electronic Science and Technology Co., Ltd. Address before: 610000 Sichuan city of Chengdu province Wuhou District Wuhou Science Park Vuko East Three Road No. 5 Patentee before: Li Chuwen |
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