CN209843654U - Clamping and carrying device for frozen sample carrying net - Google Patents

Abstract

The utility model discloses a press from both sides and carry device for freezing sample carries net, including brace table and clamp microscope carrier, be provided with the standing groove that is used for placing the holding box that carries net and is used for the installation on the brace table the mounting groove of clamp microscope carrier, the diapire of mounting groove is the slope diapire that relative horizontal plane slope set up, be equipped with the draw-in groove that is used for installing freezing sample and carries net on the clamp microscope carrier, the diapire of draw-in groove is for relative the slope diapire that the bottom surface slope of clamp microscope carrier set up, just the diapire of mounting groove with the inclination of the diapire of draw-in groove equals, makes the clamp microscope carrier install extremely during the mounting groove, the diapire of draw-in. The utility model discloses a press from both sides and carry device, the freezing sample of placing in its draw-in groove carries the net and can keep motionless, is convenient for press from both sides and carries the operation, has avoided freezing sample to carry the gliding problem of net in the draw-in groove.

Description

A clamping device for freezing sample carrying net

technical field

The utility model relates to a clamping device used for loading nets of frozen samples.

Background technique

The existing clamping device for frozen sample loading grid can clamp and fix the copper grid, and then transfer it to the frozen double-beam scanning electron microscope to apply ion beam thinning technology to finely process the sample on the copper grid .

In a conventional double-beam electron microscope with a focused ion beam function, the angle between the electron beam of the microscope and the cutting ion beam is usually 52°. For the convenience of operation, the slot for placing the copper mesh on the clamping device is also designed as With a 30° inclination angle, the copper mesh is easy to slide downward in the card slot, and falls to the bottom of the inclined surface of the clamping table. load operation.

Utility model content

In order to solve the above-mentioned technical problems, the utility model provides a clamping device for frozen sample carrying net, the frozen sample carrying net placed in the clamping slot can be kept stationary, which is convenient for carrying out clamping operation and avoids freezing sample loading. The problem with the net sliding in the card slot.

In order to achieve the purpose of the utility model, the embodiment of the utility model provides a clamping device for freezing samples carrying a net, including a support platform and a clamping platform, and the support platform is provided with a box for placing a grid The placement slot and the installation slot for installing the clamping platform, the bottom wall of the installation slot is an inclined bottom wall inclined relative to the horizontal plane, and the clamping platform is provided with a card slot for installing the frozen sample carrier network , the bottom wall of the clamping groove is an inclined bottom wall that is inclined relative to the bottom surface of the loading platform, and the bottom wall of the installation groove is at the same inclination angle as the bottom wall of the clamping groove, so that the clamping When the platform is installed in the installation groove, the bottom wall of the card groove is in a horizontal state.

The clamping device provided by the embodiment of the utility model includes a support platform and a clamping platform. Installed at the installation groove of the support platform, the clamping platform is used for clamping the frozen sample grid.

The bottom wall of the installation groove for installing the clamping platform is an inclined bottom wall that is inclined relative to the horizontal plane, the bottom wall of the card groove on the clamping platform is an inclined bottom wall that is inclined relative to the bottom surface of the clamping platform, and the installation groove The inclination angle of the bottom wall and the bottom wall of the card slot is equal, so that when the clamping platform is installed in the installation slot, the bottom wall of the card slot is in a horizontal state, which avoids the frozen sample loading net in the card slot when the bottom wall of the card slot is tilted Due to the problem of sliding, the frozen sample grid placed in the card slot can remain stationary, which is convenient for clamping operations.

Optionally, an end of the bottom wall of the installation groove that is close to the center of the support platform is inclined downward.

Optionally, the clamping device further includes an assembly platform, an installation hole is provided on the support platform, an installation column is provided below the assembly platform, and the installation column is inserted into the installation hole.

The clamping device also includes an assembly table. The mounting seat under the assembly table can be inserted into the installation hole of the support table to realize the assembly table to the support table. The bare mesh-type grid can be assembled into an autogrid on the assembly table. The assembled autogrid can be placed in the net-carrying box, and the clamping table can clamp the autogrid.

The clamping device realizes the assembly and clamping of the autogrid in the same sample operation liquid nitrogen pool, avoids ice crystal pollution during the transfer process of the sample, and improves work efficiency. In addition, by inserting the mounting column of the assembly table into the installation hole of the support table, the assembly table can be disassembled from the support table, which facilitates taking the assembly table out of the liquid nitrogen pool after the autogrid is assembled.

Optionally, the mounting post is rotatably engaged with the mounting hole, and the assembling platform is provided with a rotating hole and a lifting portion.

The mounting column of the assembly table is rotatably matched with the mounting hole of the support table, so that the assembly table can rotate relative to the support table. The assembling table can be driven to rotate by applying force to the rotating hole, so as to carry out the assembling operation of the autogrid. The assembly table can be lifted by applying force to the lifting part, so that the assembly table can be taken out from the liquid nitrogen pool.

Optionally, a diversion groove is provided on the support platform.

When the clamping platform is inserted into the installation groove of the supporting platform, liquid nitrogen can be exported from the diversion groove on the supporting platform, so as to facilitate the installation of the clamping platform.

Optionally, the clamping table includes a clamping main body and a pressing piece, the pressing piece is connected to the clamping main body by screws, the slot is arranged on the clamping main body, and the pressing piece is provided with An avoidance groove, the width of the avoidance groove is smaller than the width of the holding groove, and the edge of the avoiding groove is set to press the edge of the frozen sample carrying net in the drawing groove.

The clamping body of the clamping table is provided with a card slot for installing the frozen sample grid, and an avoidance groove is provided on the pressing piece. After the pressing piece and the clamping main body are connected by screws, the avoidance groove corresponds to the position of the clamping groove, and The width of the escape groove is smaller than the width of the clamping groove, so that the edge of the avoidance groove can be pressed against the edge of the frozen sample carrying net to realize pressing the tablet against the frozen sample carrying net.

By avoiding the edge of the groove to compress the edge of the frozen sample grid, the usable area of the frozen sample grid is hardly blocked, so there is no need to worry about not being able to select the most ideal area of the frozen sample grid. This clamping method makes the available area of the frozen sample grid unaffected, and the clamping method is more scientific.

Optionally, the clamping platform further includes an annular pad, and the annular pad is configured to be clamped between the frozen sample carrying net in the slot and the pressing piece.

When the frozen sample loading net is autogrid, it can be directly compressed by the pressing sheet; when the frozen sample loading net is a bare grid, a ring pad can be set between the bare grid and the pressing sheet to make the bare grid firmly fixed.

The clamping table can not only clamp the assembled autogrid, but also clamp the bare mesh, making the clamping table universal in application.

Optionally, the clamping body is provided with a plurality of the card slots, and the pressing piece is provided with a plurality of the avoidance grooves.

There are multiple card slots on the clamping body, and multiple avoidance slots on the pressing sheet. The multiple avoidance slots correspond to the multiple card slots one by one, so that the clamping table can hold multiple frozen samples at one time. Efficiency when screening samples.

Optionally, the loading platform further includes an anti-pollution cover, the anti-pollution cover is rotatably connected to the loading main body, so that the anti-pollution cover can cover the slot.

The anti-pollution cover is rotatably connected with the clamping body, so that the anti-pollution cover can cover the card slot and the frozen sample carrier network placed in the card slot, which can reduce the contact between the frozen sample carrier network and the outside during the transmission and transfer process, and prevent The pollution cover acts as a cold trap (ice crystal pollution is preferentially adsorbed on the anti-pollution cover), which protects the grid of frozen samples from pollution and damage. In addition, the anti-contamination cover can be opened to allow operations such as thinning processing and observation of frozen sample grids.

Optionally, the clamping body includes a dovetail block, and the installation groove includes a dovetail groove matched with the dovetail block.

The dovetail block of the clamping platform can cooperate with the dovetail groove of the mounting groove, so that the clamping platform can be fixedly assembled to the supporting platform. In addition, the freezing of the sample grid during the freezing vacuum transfer process (sampling into and out of the electron microscope), the fixation on the sample stage in the electron microscope cabin, and the observation and processing of the sample are all dependent on the dovetail. Blocks are implemented as rails.

Other features and advantages of the present invention will be set forth in the following description.

Description of drawings

The accompanying drawings are used to provide a further understanding of the technical solution of the utility model, and constitute a part of the description, together with the embodiments of the application, are used to explain the technical solution of the utility model, and do not constitute a limitation to the technical solution of the utility model.

Fig. 1 is a schematic structural view of a clamping device for freezing samples carrying a grid according to an embodiment of the present invention;

Fig. 2 is a schematic cross-sectional structure diagram of the clamping device shown in Fig. 1;

Fig. 3 is a schematic structural view of the support platform in the clamping device shown in Fig. 1;

FIG. 4 is a schematic diagram of the three-dimensional structure of the loading platform in the loading device shown in FIG. 1;

Fig. 5 is a top view structural schematic diagram of the loading platform shown in Fig. 4;

Fig. 6 is a front structural schematic diagram of the loading platform shown in Fig. 4;

Fig. 7 is a left view structural schematic diagram of the loading platform shown in Fig. 4;

Fig. 8 is a structural schematic diagram of the lifting part installed on the assembly platform of the clamping device according to the embodiment of the present invention;

Fig. 9 is a schematic cross-sectional structure diagram of the clamping device shown in Fig. 8;

Fig. 10 is a structural schematic diagram of the assembly table of the clamping device shown in Fig. 8 when it rotates;

Fig. 11 is a schematic cross-sectional structural view of the assembly table of the clamping device shown in Fig. 10 when it rotates;

Fig. 12 is a schematic diagram of the assembly structure of the clamping platform and the supporting platform according to the embodiment of the present utility model;

FIG. 13 is a schematic cross-sectional view of the assembly structure of the clamping platform and the supporting platform shown in FIG. 12 .

Reference signs:

1: clamping platform, 11: clamping body, 111: dovetail block, 112: slot, 114: slot for transmission rod, 115: via hole for transmission rod, 12: anti-pollution cover, 13: pressing sheet, 131: avoidance Groove, 133: fixing hole, 2: assembly platform, 21: mounting column, 22: rotating hole, 23: lifting part, 231: head, 232: rod part, 3: supporting platform, 31: placing groove, 32: installing Groove, 33: installation hole, 34: first diversion groove, 35: second diversion groove, 36: placement hole, 37: assembly area, 4: rotating tool.

Detailed ways

Embodiments of the utility model will be described in detail below in conjunction with the accompanying drawings.

The embodiment of the utility model provides a clamping device for freezing samples with a net, as shown in FIG. 1 and FIG. 2 , which includes a support platform 3 and a clamping platform 1 .

As shown in Fig. 1 and Fig. 3, the support platform 3 is provided with a placement groove 31 for placing a grid-carrying box, and the net-carrying box can be used to hold a frozen sample grid.

As shown in FIGS. 1-3 , the support platform 3 is also provided with an installation groove 32 for installing the clamping platform 1 , and the bottom wall of the installation groove 32 is an inclined bottom wall inclined relative to the horizontal plane. As shown in Figure 4, the clamping platform 1 is used for clamping the frozen sample grid, and is provided with a draw-in groove 112 for installing the frozen sample grid, and the bottom wall of the clamping groove 112 is inclined relative to the bottom surface of the clamping platform 1. sloped bottom wall. Wherein, the inclination angle between the bottom wall of the installation groove 32 and the bottom wall of the locking groove 112 is equal, so that when the loading platform 1 is installed in the installation groove 32, the bottom wall of the locking groove 112 is in a horizontal state, as shown in FIG. 2 .

The clamping platform 1 installed to the installation groove 32, the bottom wall of the slot 112 is in a horizontal state, avoiding the problem that the frozen sample carrying network in the slot 112 slides when the bottom wall of the slot 112 is tilted, so that it is placed in the slot. The frozen sample carrying net in the groove 112 can remain stationary, which is convenient for carrying out the clamping operation.

Optionally, one end of the bottom wall of the installation groove 32 that is close to the center of the supporting platform 3 is inclined downward. As shown in Figure 2, after the loading platform 1 is installed in the installation groove 32, the end of the loading platform 1 close to the center of the supporting platform 3 is also inclined downward, so that the loading platform 1 can be firmly held in the installation groove 32 .

Optionally, as shown in Figures 1-3, the clamping device also includes an assembly platform 2, and a mounting hole 33 is provided on the support platform 3, and a mounting column 21 is provided below the assembly platform 2, and the mounting column 21 is inserted into the mounting hole 33 Inside. Specifically, as shown in FIG. 1 and FIG. 3 , a plurality of placement slots 31 are provided around the support platform 3 , and an assembly area 37 is formed in the center of the support platform 3 , and the assembly platform 2 is located in the assembly area 37 .

After the mounting seat below the assembly platform 2 is inserted into the installation hole 33 of the support platform 3, the assembly platform 2 can be assembled on the support platform 3, and the bare mesh-type grid can be assembled into an autogrid on the assembly platform 2, and the assembled The autogrid can be placed in the net carrying box, and the clamping platform 1 can clamp the autogrid.

The clamping device integrates the assembly and clamping of the frozen sample grid to form a complete system, which realizes the assembly and clamping of the autogrid in the same sample operation liquid nitrogen pool, and avoids the need for samples to be transferred during the transfer process. Form ice crystal pollution and improve work efficiency. In addition, by inserting the mounting column 21 of the assembly table 2 into the mounting hole 33 of the support table 3, the assembly table 2 is easy to disassemble, and it is convenient to assemble the assembly table 2 to the support table before assembly, and to install the assembly table 2 after the autogrid assembly is completed. Remove from liquid nitrogen pool.

Optionally, the mounting column 21 is rotatably engaged with the mounting hole 33 , so that the assembly platform 2 can rotate relative to the supporting platform 3 . Further, as shown in FIG. 1, a rotating hole 22 is provided on the assembly table 2. By applying force to the rotating hole 22, for example, as shown in FIGS. 10 and 11, the rotating tool 4 can be used to move the rotating hole 22, The assembly table 2 is driven to rotate so as to carry out the assembly operation of the autogrid.

Optionally, as shown in FIGS. 8 and 9 , a lifting portion 23 is provided on the assembly platform 2 . By applying force to the lifting portion 23, the assembly platform 2 can be lifted, so as to take the assembly platform 2 out of the liquid nitrogen pool. Specifically, as shown in FIG. 9 , the lifting part 23 may include a rod part 232 and a head part 231 , the lower part of the rod part 232 may be connected to the assembly platform 2 , and the upper part of the rod part 232 may be connected to the head part 231 . The assembly stand 2 can be lifted by gripping the rod portion 232 with tweezers or the like. After the assembly platform 2 is taken out from the support platform 3 , the assembly structure of the loading platform 1 and the support platform 3 is shown in FIG. 12 and FIG. 13 .

Optionally, a diversion groove is provided on the support platform 3 . Specifically, as shown in FIGS. 1 and 3 , the flow guide groove may include a first flow guide groove 34 and a second flow guide groove 35 located on both sides of the installation groove 32 . Certainly, the position and quantity of the diversion grooves can be set arbitrarily according to needs, and are not limited to those shown in FIG. 1 and FIG. 3 .

When the clamping platform 1 is inserted into the installation groove 32 of the support platform 3 , the liquid nitrogen can be led out from the first flow guide groove 34 and the second flow guide groove 35 on the support platform 3 to facilitate the installation of the clamping platform 1 .

Optionally, as shown in FIGS. 4-7 , the loading platform 1 includes a loading main body 11 and a pressing piece 13 , and the pressing piece 13 is connected to the loading main body 11 by screws. Specifically, as shown in FIGS. 4 and 5 , the pressing piece 13 is provided with fixing holes 133 for passing screws.

On the one hand, the screw connection can fix the pressing piece 13 and the holding body 11, and on the other hand, the distance between the pressing piece 13 and the holding body 11 can be adjusted, which is convenient for compressing frozen sample grids of different thicknesses and adjusting the pressing force .

As shown in Figures 4 and 5, the draw-in groove 112 is arranged on the clamping body 11, and the pressing piece 13 is provided with an avoidance groove 131. After the pressing piece 13 and the carrying body 11 are connected by screws, the avoidance groove 131 and the draw-in groove The position of 112 corresponds.

As shown in Fig. 4 and Fig. 5, the width of avoidance groove 131 is less than the width of draw-in groove 112 (the width direction is along the left-right direction in Fig. 5), and the edge of avoidance groove 131 is arranged to compress the frozen sample carrying net in draw-in groove 112 edge. In this way, the edge of the avoidance groove 131 can be used to press the edge of the frozen sample grid, so that the pressing piece 13 can press the frozen sample grid.

By avoiding the edge of the groove 131 to press the edge of the frozen sample grid, the available area of the frozen sample grid is hardly covered, so there is no need to worry about not being able to select the most ideal area of the frozen sample grid. This clamping method makes the available area of the frozen sample grid unaffected, and the clamping method is more scientific.

Optionally, the clamping platform 1 further includes an annular pad (not shown in the figure), and the annular pad is arranged to be clamped between the frozen sample carrier net in the slot 112 and the pressing sheet 13 .

When the frozen sample loading net is an autogrid, it can be compressed directly by using the pressing sheet 13 . During installation, after the autogrid is placed in the card slot 112, the pressing piece 13 is fixed on the clamping main body 11 by screws, so as to compress the autogrid.

When the frozen sample carrying net is a bare net, an annular pad can be arranged between the bare net and the pressing sheet 13, so that the bare net is firmly fixed. When installing, the bare net can be placed in the slot 112 first, then the ring pad is placed on the bare net, and finally the pressing piece 13 is fixed on the clamping main body 11 by screws, and the ring pad and the bare net are pressed with the pressing piece 13.

By screwing the screw, the distance between the pressing piece 13 and the clamping body 11 can be adjusted, so that the clamping table 1 can not only clamp the assembled autogrid, but also clamp the bare mesh, so that the clamping table 1 has universal application sex. Because the bare mesh can be clamped, on the one hand, the bare mesh processed and thinned in the scanning electron microscope can be transferred to the sample rod of the ordinary transmission electron microscope for observation, and on the other hand, the copper mesh sample can be simply clamped for observation in the scanning electron microscope.

Optionally, the annular gasket is an O-ring. Further, the height of the O-ring can be substantially equal to the height of the autogrid. Furthermore, the outer diameter of the O-ring, the outer diameter of the autogrid, and the width of the locking groove 112 may be substantially equal.

Optionally, the clamping body 11 is provided with a plurality of card slots 112 , and the pressing piece 13 is provided with a plurality of avoidance grooves 131 . Specifically, as shown in FIG. 4 and FIG. 5 , the carrying body 11 is provided with two locking grooves 112 , and the pressing piece 13 is provided with two escape grooves 131 . Of course, the number of card slots 112 is not limited to two, and may be one, three or more than three.

The clamping main body 11 is provided with a plurality of card slots 112, and the pressing piece 13 is provided with a plurality of avoidance grooves 131, and the plurality of avoidance grooves 131 correspond to the plurality of draw-in slots 112 one by one, so that the clamping table 1 can carry more than one load at a time. A frozen sample grid improves the efficiency of screening samples.

Optionally, as shown in FIGS. 4-7 , the loading platform 1 further includes an anti-pollution cover 12 , which is rotatably connected to the loading body 11 , so that the anti-pollution cover 12 can cover the slot 112 .

After the anti-pollution cover 12 rotates, it can cover the pressing piece 13, the draw-in slot 112 and the frozen sample carrier net placed in the draw-in slot 112, which can reduce the contact between the frozen sample carrier net and the outside during the transmission and transfer process, and the anti-pollution cover It acts as a cold trap (ice crystal pollution is preferentially adsorbed on the anti-pollution cover), so that the grid of frozen samples is protected from pollution and damage. In addition, the anti-pollution cover 12 can be rotated and opened, so that operations such as thinning processing and observation of the frozen sample carrier net can be performed.

Optionally, as shown in FIG. 4 and FIG. 6 , the clamping body 11 includes a dovetail block 111 , and the mounting groove 32 includes a dovetail groove matching with the dovetail block 111 . Specifically, the dovetail block 111 can be located at the bottom of the clamping body 11 , and correspondingly, the dovetail groove can also be located at the bottom of the installation groove 32 .

The dovetail block 111 of the loading platform 1 can cooperate with the dovetail groove of the mounting groove 32 so that the loading platform 1 is fixedly assembled to the supporting platform 3 . In addition, the freezing of the sample grid during the freezing vacuum transfer process (sampling into and out of the electron microscope), the fixation on the sample stage in the electron microscope cabin, and the observation and processing of the sample are all dependent on the dovetail. Block 111 is implemented as a rail.

Optionally, as shown in Figures 1 and 3, a placement hole 36 is also provided on the support platform 3, which can be used to place tweezers and pre-cool the tweezers, so that the tweezers can be used to assemble the frozen sample carrier network , clamping and other operations.

Optionally, as shown in FIG. 4 and FIG. 6 , the clamping body 11 is provided with a transmission rod slot 114 and a transmission rod through hole 115 . During the process of transporting the frozen sample loading net, the rod portion of the transmission rod can be inserted into the transmission rod through hole 115, and the head of the transmission rod can pass through the transmission rod slot 114, and then rotate 90°, so as to realize The positioning assembly of the transmission rod and the clamping platform 1.

In summary, the clamping device for carrying frozen samples provided by the embodiment of the utility model has the following beneficial effects:

1. It can not only carry the assembled autogrid, but also carry the bare grid, and the application is universal;

2. Multiple frozen samples can be loaded at one time;

3. In a clamping device, the bare net can be quickly and efficiently assembled in a liquid nitrogen environment to form an autogrid, and it can be clamped and fixed on a special clamping platform, or the bare net can be clamped and fixed on a clamping platform;

4. When clamping, press the edge area of the frozen sample grid, and the available area of the frozen sample grid will not be affected;

5. The grid for frozen samples is placed stably in the slot and is convenient for loading.

While the invention has been described with reference to exemplary embodiments of the invention, it is to be understood that the invention is not limited to the above-described embodiments or constructions. In addition, while the various elements of the disclosed invention are shown in various exemplary combinations and configurations, other combinations and configurations, including more, less, or only a single element, are also within the scope of the appended claims. Inside.

Although the embodiments disclosed in the present utility model are as above, the content described is only an embodiment adopted to facilitate understanding of the present utility model, and is not intended to limit the present utility model. Anyone skilled in the field of the utility model can make any modifications and changes in the form and details of the implementation without departing from the spirit and scope disclosed by the utility model, but the patent protection scope of the utility model , must still be defined by the appended claims shall prevail.

Claims (10)

1. The clamping and carrying device for the frozen sample carrying net is characterized by comprising a supporting table and a clamping and carrying table, wherein a placing groove for placing a carrying net containing box and a mounting groove for mounting the clamping and carrying table are arranged on the supporting table, the bottom wall of the mounting groove is an inclined bottom wall which is inclined relative to the horizontal plane, a clamping groove for mounting the frozen sample carrying net is arranged on the clamping and carrying table, the bottom wall of the clamping groove is an inclined bottom wall which is inclined relative to the bottom surface of the clamping and carrying table, the inclination angle of the bottom wall of the mounting groove is equal to that of the bottom wall of the clamping groove, and when the clamping and carrying table is mounted to the mounting groove, the bottom wall of the clamping groove is in a horizontal.

2. The clamp loading device according to claim 1, wherein an end of the bottom wall of the mounting groove near the center of the support table is inclined downward.

3. The clamp carrier device according to claim 1, further comprising an assembly table, wherein the support table is provided with mounting holes, and mounting posts are arranged below the assembly table and inserted into the mounting holes.

4. The clamp carrier device of claim 3, wherein said mounting posts are pivotally engaged with said mounting holes, and said assembly table is provided with pivot holes and a lift portion.

5. The clamp loading device according to any one of claims 1 to 4, wherein a guide groove is provided on the support table.

6. The clamping device according to any one of claims 1 to 4, wherein the clamping stage comprises a clamping main body and a pressing plate, the pressing plate is fixed to the clamping main body through screws, the clamping groove is formed in the clamping main body, an avoiding groove is formed in the pressing plate, the width of the avoiding groove is smaller than that of the clamping groove, and the edge of the avoiding groove is configured to press the edge of the frozen sample carrying net in the clamping groove.

7. The clamp carrier device of claim 6, wherein the clamp stage further comprises an annular pad configured to be clamped between the frozen sample carrier web and the compression pad within the card slot.

8. The clamp carrier device according to claim 6, wherein a plurality of the engaging grooves are formed on the clamp carrier body, and a plurality of the avoiding grooves are formed on the pressing plate.

9. The clamp carrier device of claim 6, wherein the clamp carrier further comprises a contamination cover rotatably coupled to the clamp carrier body such that the contamination cover covers the card slot.

10. The clamp carrier device of claim 6, wherein said clamp carrier body includes a dovetail block, and said mounting slot includes a dovetail slot that mates with said dovetail block.