CN208201000U - A kind of novel T cell culture dish for being conveniently replaceable culture medium - Google Patents
A kind of novel T cell culture dish for being conveniently replaceable culture medium Download PDFInfo
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- CN208201000U CN208201000U CN201820503349.0U CN201820503349U CN208201000U CN 208201000 U CN208201000 U CN 208201000U CN 201820503349 U CN201820503349 U CN 201820503349U CN 208201000 U CN208201000 U CN 208201000U
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- 239000001963 growth medium Substances 0.000 title claims abstract description 36
- 210000001744 T-lymphocyte Anatomy 0.000 title claims abstract description 22
- 238000004113 cell culture Methods 0.000 title claims abstract description 14
- 239000007788 liquid Substances 0.000 claims abstract description 18
- 239000012530 fluid Substances 0.000 claims abstract description 12
- 238000007789 sealing Methods 0.000 claims 1
- 239000002699 waste material Substances 0.000 description 5
- 230000006872 improvement Effects 0.000 description 4
- 230000001850 reproductive effect Effects 0.000 description 3
- 230000008901 benefit Effects 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000001815 biotherapy Methods 0.000 description 1
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 210000002443 helper t lymphocyte Anatomy 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model provides a kind of novel T cell culture dish for being conveniently replaceable culture medium, including interior ware and cover the outer ware outside interior ware, the mouth rim of its interior ware is placed on the oral area end face of outer ware, and interior ware oral area is provided with ware lid, the bottom of the interior ware is provided with via hole, and the orifice part of via hole is provided with baffle, outer ware includes ware seat, the edge placement that outer ware corresponds to via hole is provided with flange, flange surrounds to be arranged to be magnetic in space and seals up a door and be slidably connected with flange inner wall, it is provided with liquid outlet on flange and is provided with strainer, outer ware bottom is provided with leakage fluid dram, it is arranged at the spatial position that ware seat corresponding flange surrounds fluted, electromagnet is provided in groove, this culture dish is upper and lower using magnet control closure door, the connected relation between interior ware and outer ware is controlled with this, culture medium resource is not wasted, reduce cost.
Description
Technical field
The utility model relates to a kind of novel T cell culture dishes for being conveniently replaceable culture medium.
Background technique
T cell is segmented into many types, such as cytotoxic T cell according to function and surface marker, T helper cell, adjust/
Inhibit T cell etc., with the development of biological therapy clinical application, T cell is more and more wider in the research and application of medical field
General, and the use of T cell for the premise of clinical treatment is to have enough T cells, generally in-vitro multiplication uses culture dish etc.
Utensil is carrier, but during the cultivation process, needs often to carry out the replacement of culture medium, and non-closed environment be easy to cause pollution,
The replacement inconvenience of culture medium；In response to this problem, occurs the culture apparatus of inside and outside ware structure on the market, inside and outside ware bottom is deposited
In gap, connected by via hole, waste liquid can be extracted out through gap through outer ware, but when such device addition culture medium, culture medium will be first
Full of the gap between inside and outside ware, the waste of culture medium is caused, cost is improved.
Utility model content
In view of this, the purpose of the utility model is to provide a kind of novel T cell culture dish for being conveniently replaceable culture medium,
Resource can be rationally utilized, cost is reduced, quick-replaceable culture medium improves T cell reproductive efficiency.
In order to solve the above technical problems, the technical solution of the utility model is:
A kind of novel T cell culture dish for being conveniently replaceable culture medium including interior ware and covers the outer ware outside interior ware,
The mouth rim of interior ware is placed on the oral area end face of outer ware, and interior ware oral area is provided with ware lid, the bottom setting of the interior ware
There is via hole, and the orifice part of via hole is provided with baffle, outer ware includes ware seat, and the edge placement that outer ware corresponds to via hole is provided with convex
Edge, flange surround to be arranged to be magnetic in space and seal up a door and be slidably connected with flange inner wall, liquid outlet is provided on flange and is provided with
Strainer, outer ware bottom are provided with leakage fluid dram, and setting is fluted at the spatial position that ware seat corresponding flange surrounds, and electricity is provided in groove
Magnet.
This culture dish is upper and lower using magnet control closure door, controls the connected relation between interior ware and outer ware with this, on
It goes and seals via hole, culture medium can be added, because via hole blocks, culture medium does not enter outer ware, and downlink opens via hole, and culture medium is along liquid out
Gap of the mouth after filtering between inside and outside ware is discharged through leakage fluid dram, does not waste culture medium resource, reduces cost.
Further, it is provided with pipeline on the leakage fluid dram, is provided with drawing liquid pump on pipeline, is convenient for quick-replaceable culture medium.
Further, it is provided with the control button to control electromagnet on the ware seat, facilitates operation.
Further, sliding slot is provided in the flange inner wall, the smooth slot of closure door edge protrusion is mobile,.
Further, the sliding slot upwardly extends until baffle, sliding slot guiding closure door, prevent from not advising in magneticaction seal door below
It then moves, baffle can limit closure door up stroke.
Further, the flange surrounds the bottom notch grooving in space, is provided with closure door in slot.
Further, the closure door is that second level is stepped, and when closure door comes downwards to stroke end, the second terrace is lower than in outer ware bottom
Wall, when closure door goes upward to stroke end, the first terrace is bonded baffle, and the first terrace thickness is consistent with Weir Plate Thickness, at closure door
When in the slot that flange surrounds, the second terrace is lower than outer ware bottom interior wall, and culture medium can not be interfered to flow out along liquid outlet, and raising is changed
Liquid efficiency, when going upward to baffle, the seamless applying baffle of the first terrace, good airproof performance, interior ware bottom is smooth, and culture medium can be quick
Diffusion.
The utility model has the beneficial effects that this culture dish, which has, rationally utilizes resource, cost, quick-replaceable culture are reduced
The advantages of base, raising T cell reproductive efficiency.
Detailed description of the invention
Fig. 1: the structure chart of the utility model；
Fig. 2: the closure door of the utility model and the connection structure diagram of flange；
In figure: 1, interior ware；1.1, ware lid；1.2, edge；1.3, baffle；2, outer ware；2.1, flange；2.11, sliding slot；2.2,
Closure door；2.21, protrusion；2.3, liquid outlet；2.4, leakage fluid dram；2.5, pipeline；2.6, drawing liquid pump；2.7, strainer；3, ware seat；
3.1, groove；3.2, control button；4, electromagnet；A, via hole.
Specific embodiment
Below in conjunction with attached drawing, specific embodiment of the present utility model is described in further detail, so that the utility model skill
Art scheme is more readily understood and grasps.
Fig. 1 illustrates the specific structure of the novel T cell culture dish for being conveniently replaceable culture medium, including interior ware 1 and set
Outer ware 2 outside interior ware 1, the mouth rim 1.2 of interior ware 1 are placed on the oral area end face of outer ware 2, replace culture dish when
Wait more convenient, and 1 oral area of interior ware is provided with ware lid 1.1, it is preferable that can the aperture in ware lid 1.1, for fluid injection, the interior ware 1
Bottom be provided with via hole a, via hole a is used to that waste liquid is discharged, and carries out the replacement of culture medium, and the orifice part of via hole a is provided with gear
Plate 1.3, outer ware 2 include ware seat 3, and the edge placement of the corresponding via hole a of outer ware 2 is provided with flange 2.1, and flange 2.1 surrounds in space
The setting closure door that is magnetic 2.2 and is slidably connected with 2.1 inner wall of flange, and liquid outlet 2.3 is provided on flange 2.1 and is provided with strainer
2.7, outer 2 bottom of ware is provided with leakage fluid dram 2.4, is arranged fluted 3.1 at the spatial position that 3 corresponding flange 2.1 of ware seat surrounds, groove
Electromagnet 4 is provided in 3.1, as shown in Fig. 2, it is provided with sliding slot 2.11 on 2.1 inner wall of flange, it can be in the magneticaction of electromagnet 4
Under, 2.2 edge protrusion of closure door, the 2.21 mobile closed via hole a of smooth slot 2.11, further, the sliding slot 2.11 upwardly extends directly
To baffle 1.3, the guiding of sliding slot 2.11 closure door 2.2 prevents from moving irregularly in magneticaction seal door below 2.2, baffle 1.3 can limit
It seals up a door 2.2 up strokes,.
This culture dish using electromagnet 4 control closure door 2.2 up and down, with this control the connection between interior ware 1 and outer ware 2 close
System, uplink seal via hole a, culture medium can be added, and because via hole a is blocked, culture medium does not enter outer ware 2, and downlink opens via hole a, training
It supports base to be discharged along gap of the liquid outlet 2.3 after filtering between inside and outside ware 2 through leakage fluid dram 2.4, does not waste culture medium resource,
Reduce cost.
As a further improvement, it is provided with pipeline 2.5 on the leakage fluid dram 2.4, is provided with drawing liquid pump on pipeline 2.5
2.6, it is drawn from the useless culture solution of via hole a discharge by drawing liquid pump 2.6, is convenient for quick-replaceable culture medium.
As a further improvement, it is provided with the control button 3.2 to control electromagnet 4 on the ware seat 3, facilitates behaviour
Make.
As a further improvement, the flange 2.1 surrounds the bottom notch grooving in space, is provided with closure door in slot
2.2, closure door 2.2 is arranged in slot, and closure door 2.2 does not impact leakage fluid dram 2.4 when drain.
As a further improvement, the closure door 2.2 is stepped for second level, when closure door 2.2 comes downwards to stroke end, second-order
Face is lower than outer 2 bottom interior wall of ware, and when closure door 2.2 goes upward to stroke end, the first terrace is bonded baffle 1.3, and the first terrace thickness
With 1.3 consistency of thickness of baffle, when closure door 2.2 is in the slot that flange 2.1 surrounds, the second terrace is lower than outer 2 bottom interior wall of ware,
Culture medium can not be interfered to flow out along liquid outlet 2.3, liquid efficiency is changed in raising, and when going upward to baffle 1.3, the first terrace is seamless applying
Baffle 1.3, good airproof performance, interior 1 bottom of ware is smooth, and culture medium can quickly be spread.
This culture dish, which has, rationally utilizes resource, reduces cost, and quick-replaceable culture medium improves T cell reproductive efficiency
Advantage.
Certainly, the above is only the specific application examples of the utility model, do not constitute and appoint to the protection scope of the utility model
What is limited.Any technical scheme formed by adopting equivalent transformation or equivalent replacement, all falls within the utility model rights protection model
Within enclosing.
Claims (7)
1. a kind of novel T cell culture dish for being conveniently replaceable culture medium, including interior ware and covers the outer ware outside interior ware, in
The mouth rim of ware is placed on the oral area end face of outer ware, and interior ware oral area is provided with ware lid, which is characterized in that the interior ware
Bottom is provided with via hole, and the orifice part of via hole is provided with baffle, and outer ware includes ware seat, and the edge placement that outer ware corresponds to via hole is set
Be equipped with flange, flange surrounds setting in space and is magnetic closure door and to be slidably connected with flange inner wall, be provided on flange liquid outlet and
It is provided with strainer, outer ware bottom is provided with leakage fluid dram, and setting is fluted at the spatial position that ware seat corresponding flange surrounds, and sets in groove
It is equipped with electromagnet.
2. the novel T cell culture dish for being conveniently replaceable culture medium of one kind according to claim 1, which is characterized in that institute
It states and is provided with pipeline on leakage fluid dram, be provided with drawing liquid pump on pipeline.
3. the novel T cell culture dish for being conveniently replaceable culture medium of one kind according to claim 1, which is characterized in that institute
State the control button being provided on ware seat to control electromagnet.
4. the novel T cell culture dish for being conveniently replaceable culture medium of one kind according to claim 1, which is characterized in that institute
It states and is provided with sliding slot in flange inner wall, the smooth slot of closure door edge protrusion is mobile.
5. the novel T cell culture dish for being conveniently replaceable culture medium of one kind according to claim 4, which is characterized in that institute
Sliding slot is stated to upwardly extend until baffle.
6. the novel T cell culture dish for being conveniently replaceable culture medium of one kind according to claim 1, which is characterized in that institute
It states flange and surrounds bottom notch grooving in space, be provided with closure door in slot.
7. the novel T cell culture dish for being conveniently replaceable culture medium of -6 any described one kind, feature exist according to claim 1
In the closure door is that second level is stepped, and when closure door comes downwards to stroke end, the second terrace is lower than outer ware bottom interior wall, uplink of sealing up a door
When to stroke end, the first terrace is bonded baffle, and the first terrace thickness is consistent with Weir Plate Thickness.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820503349.0U CN208201000U (en) | 2018-04-10 | 2018-04-10 | A kind of novel T cell culture dish for being conveniently replaceable culture medium |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820503349.0U CN208201000U (en) | 2018-04-10 | 2018-04-10 | A kind of novel T cell culture dish for being conveniently replaceable culture medium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208201000U true CN208201000U (en) | 2018-12-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820503349.0U Active CN208201000U (en) | 2018-04-10 | 2018-04-10 | A kind of novel T cell culture dish for being conveniently replaceable culture medium |
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| CN (1) | CN208201000U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118516232A (en) * | 2024-06-27 | 2024-08-20 | 东莞市石碣医院 | A stem cell culture device for breast cancer immunotherapy |
| CN118895198A (en) * | 2024-10-08 | 2024-11-05 | 南方医科大学南方医院 | A carrier device and method for automatically adding drugs to cultured cells |
| US12226008B2 (en) | 2017-12-20 | 2025-02-18 | The Gillette Company Llc | Manual toothbrush |
-
2018
- 2018-04-10 CN CN201820503349.0U patent/CN208201000U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12226008B2 (en) | 2017-12-20 | 2025-02-18 | The Gillette Company Llc | Manual toothbrush |
| CN118516232A (en) * | 2024-06-27 | 2024-08-20 | 东莞市石碣医院 | A stem cell culture device for breast cancer immunotherapy |
| CN118895198A (en) * | 2024-10-08 | 2024-11-05 | 南方医科大学南方医院 | A carrier device and method for automatically adding drugs to cultured cells |
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