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CN206792814U - External beam radiotherapy system - Google Patents

External beam radiotherapy system Download PDF

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CN206792814U
CN206792814U CN201490001361.1U CN201490001361U CN206792814U CN 206792814 U CN206792814 U CN 206792814U CN 201490001361 U CN201490001361 U CN 201490001361U CN 206792814 U CN206792814 U CN 206792814U
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radiation
compartment
radiation source
radiotherapy system
patient
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摩西·艾因-高尔
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077Beam delivery systems
    • A61N5/1079Sharing a beam by multiple treatment stations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092Details
    • A61N2005/1094Shielding, protecting against radiation

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  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Abstract

An external beam radiotherapy system includes a plurality of compartments separated from each other by a radiation shield. Each compartment includes a patient support system including a support member and a fixation member for supporting and spatially fixing a target portion of a patient for irradiation. The radiation source housing includes at least one radiation source operable to emit a beam of radiation into the compartments towards the target portion in each compartment. Each compartment comprises a beam shaper for shaping a radiation beam emitted into the compartment. The radiation shield is configured to provide sufficient shielding in each compartment from radiation generated in other compartments according to a safety standard.

Description

一种体外射束放射治疗系统An external beam radiotherapy system

技术领域technical field

本发明总体上涉及放射治疗和辐射系统,以及特别地涉及用于体外射束放射治疗的系统和方法,特别是用于多个患者的治疗。The present invention relates generally to radiation therapy and radiation systems, and in particular to systems and methods for external beam radiation therapy, especially for the treatment of multiple patients.

背景技术Background technique

体外射束放射治疗(EBRT)包括以典型是兆伏光子的外射束辐射患者内靶标。历史上,该射束已经通过使用Co60同位素放射源的放射性钴远距离治疗设备来生成。辐射源被屏蔽并安装于在垂直平面内旋转的台架上并朝向水平定位的患者发射射束。External beam radiation therapy (EBRT) involves irradiating a target within a patient with an external beam of typically megavolt photons. Historically, this beam has been generated by radioactive cobalt teletherapy devices using a Co 60 isotope radioactive source. The radiation source is shielded and mounted on a gantry that rotates in a vertical plane and emits a beam towards a horizontally positioned patient.

线性加速器(直线加速器)已经被优选用于钴辐射器,这是由于它们的更高能量(其具有更深穿透的优点)、更高强度(其具有更短治疗时间的优点)、以及更低半影(其具有更高质量的剂量射送的优点)。直线加速器辐射束通过朝向靶标在真空中加速电子来生成。直线加速器通常比Co-60辐射器更昂贵且需要更复杂的维护。Linear accelerators (linear accelerators) have been preferred for cobalt irradiators due to their higher energy (which has the advantage of deeper penetration), higher intensity (which has the advantage of shorter treatment time), and lower Penumbra (which has the advantage of higher quality dose delivery). Linac radiation beams are generated by accelerating electrons in a vacuum towards a target. Linear accelerators are generally more expensive and require more complex maintenance than Co-60 irradiators.

关闭辐射束,也就是,使得系统不对靶标发射辐射束,在直线加速器电子地实现而在放射性钴远距离治疗设备机械地实现,诸如通过将源移动远离初级准直器至屏蔽位置。这也能够通过使用衰减快门来封堵射束来实现。Turning off the radiation beam, ie so that the system does not emit the radiation beam at the target, is accomplished electronically at the linac and mechanically at the radiocobalt teletherapy device, such as by moving the source away from the primary collimator to a shielded position. This can also be achieved by blocking the beam using an attenuating shutter.

对治疗室或治疗区域的内侧及外侧实现EBRT屏蔽。对治疗室内侧,源外壳(其基本围绕源,除了发射射束的位置)提供了对不期望辐射的防护。对治疗室外侧,系统外壳(例如,拱顶)提供防护。足够的屏蔽是依据国际和当地标准。EBRT shielding of the inside and outside of the treatment room or treatment area. To the inside of the treatment room, the source enclosure (which substantially surrounds the source, except where the beam is emitted) provides shielding from unwanted radiation. To the outside of the treatment room, the system enclosure (eg, dome) provides protection. Adequate shielding is based on international and local standards.

源外壳通常包括围绕源的衰减容器和作为辐射束唯一通道的固定初级准直器。另外的准直器可设置用于对束孔径成形。The source enclosure typically consists of an attenuating vessel surrounding the source and a fixed primary collimator as the only passage for the radiation beam. Additional collimators may be provided for shaping the beam aperture.

拱顶不仅使免受直接(初级)射束还使免受从辐射设备及其束成形器泄漏而产生的二次辐射,以及从所治疗患者、房间墙壁等散射的辐射。The vault protects not only from the direct (primary) beam but also from secondary radiation resulting from leakage from the radiation device and its beam shaper, as well as radiation scattered from the treated patient, room walls, etc.

典型的EBRT治疗排序为多个时间分数。分数辐射时间是在几分钟的范围内。增加所输送剂量率减小分数辐射时间并可增加EBRT系统吞吐量。Typical EBRT treatments are sequenced as multiple time fractions. Fractional radiation times are in the range of minutes. Increasing the delivered dose rate reduces fractional radiation time and can increase EBRT system throughput.

在弧放射治疗中,在射束在通常垂直于患者的平面内绕患者旋转时连续地辐射患者。能够通过包含(subtending)整圆的弧来输送完整部分,这减少了治疗时间。尽管另外的顺序输送的圆锥弧(即,射束不垂直于患者)会增加剂量输送,如此额外的弧通常不实现用于身体辐射治疗。In arc radiation therapy, the patient is continuously irradiated as the beam rotates around the patient in a plane generally perpendicular to the patient. The ability to deliver complete sections through an arc subtending a full circle reduces treatment time. Although additional sequentially delivered conical arcs (ie, beams not perpendicular to the patient) would increase dose delivery, such additional arcs are generally not implemented for body radiation therapy.

发明内容Contents of the invention

本发明试图提供一种用于体外射束放射治疗的新型系统和方法,如下文中所描述。The present invention seeks to provide a novel system and method for external beam radiation therapy, as described hereinafter.

根据本发明的实施方式因此提供了一种体外射束放射治疗系统,其包括由辐射屏蔽彼此间隔开的多个隔间,每个隔间包括患者支撑系统,其包括支撑构件和固定构件,用于支撑并空间地固定患者的进行辐射的靶标部分,以及辐射源外壳,其包括至少一个辐射源,可操作以朝向每个隔间中的靶标部分发射辐射束至隔间,其中每个隔间包括束成形器,用于对发射进入该隔间的辐射束成形,并且其中辐射屏蔽被配置为根据安全标准在每个隔间中对其他隔间中生成的辐射提供足够屏蔽,并且其中至少一个辐射源朝向每个隔间经过不同通道全方位地发射辐射束,其中至少一个辐射源包括线性加速器,其可操作以朝向辐射生成靶标在真空中顺序地偏转加速电子束,其中每个辐射生成靶标被构造以允许辐射被朝向隔间中的特定隔间引导。Embodiments according to the present invention thus provide an external beam radiation therapy system comprising a plurality of compartments spaced from one another by radiation shielding, each compartment comprising a patient support system comprising a support member and a fixation member for for supporting and spatially fixing a target portion of a patient to be irradiated, and a radiation source housing including at least one radiation source operable to emit a beam of radiation toward the target portion in each compartment, wherein each compartment comprising a beam shaper for shaping the radiation beam emitted into the compartment, and wherein the radiation shields are configured to provide adequate shielding in each compartment from radiation generated in the other compartments in accordance with safety standards, and at least one of the Radiation sources emit radiation beams omnidirectionally through different channels towards each compartment, wherein at least one radiation source comprises a linear accelerator operable to sequentially deflect a beam of accelerated electrons in vacuum toward radiation generating targets, wherein each radiation generating target configured to allow radiation to be directed towards a particular one of the compartments.

在一个非限制性实施方式中,射束通常是水平的,并且其中针对至少一个隔间,患者支撑系统可操作以绕通常垂直的旋转轴转动。In one non-limiting embodiment, the beam is generally horizontal, and wherein for at least one compartment, the patient support system is operable to rotate about a generally vertical axis of rotation.

在一个非限制性实施方式中,所述至少一个辐射源包括线性加速器,其可操作以朝向辐射生成靶标在真空中顺序地偏转加速电子束,其中每个辐射生成靶标被引导至各隔间中的特定隔间。In one non-limiting embodiment, said at least one radiation source comprises a linear accelerator operable to sequentially deflect a beam of accelerated electrons in vacuum towards radiation generating targets, wherein each radiation generating target is directed into a respective compartment specific compartment.

在一个非限制性实施方式中,所述至少一个辐射源可绕旋转轴旋转并配置为在所述至少一个辐射源旋转期间朝向特定隔间发射辐射束。In one non-limiting embodiment, the at least one radiation source is rotatable about an axis of rotation and is configured to emit a radiation beam towards a particular compartment during rotation of the at least one radiation source.

在一个非限制性实施方式中,所述至少一个辐射源全方位地发射射束,从而同时向每个隔间发射辐射束。In one non-limiting embodiment, the at least one radiation source emits beams omnidirectionally, thereby emitting radiation beams to each compartment simultaneously.

在一个非限制性实施方式中,提供辐射拦截器来选择性封堵所述至少一个辐射束被发射到至少一个隔间内。In one non-limiting embodiment, a radiation interceptor is provided to selectively block said at least one radiation beam from being emitted into at least one compartment.

在一个非限制性实施方式中,所述至少一个支撑构件配置为以与另一隔间中的另一支撑构件不同的方位支撑一个隔间中的患者。In one non-limiting embodiment, the at least one support member is configured to support a patient in one compartment in a different orientation than another support member in another compartment.

在一个非限制性实施方式中,该系统用于EBRT的方法中以辐射不同隔间内的患者,患者可基本同时地或顺序地辐射。In one non-limiting embodiment, the system is used in a method of EBRT to irradiate patients in different compartments, patients may be irradiated substantially simultaneously or sequentially.

附图说明Description of drawings

本发明将通过下述详细描述并结合附图而得到更加全面地理解和体会,其中:The present invention will be more fully understood and appreciated through the following detailed description in conjunction with the accompanying drawings, wherein:

图1是根据本发明实施方式构造和可操作的体外射束治疗系统的简化示意图;以及Figure 1 is a simplified schematic diagram of an extracorporeal beam therapy system constructed and operative in accordance with an embodiment of the present invention; and

图2是根据本发明实施方式的图1的EBRT系统中一个隔间的简化示意图。2 is a simplified schematic diagram of a compartment in the EBRT system of FIG. 1 in accordance with an embodiment of the invention.

具体实施方式detailed description

现在将参照图1,其示意了根据本发明非限制实施方式构造和可操作的体外射束治疗系统10。Reference will now be made to FIG. 1 , which illustrates an external beam therapy system 10 constructed and operative in accordance with a non-limiting embodiment of the present invention.

EBRT系统10包括由辐射屏蔽14彼此间隔开的多个隔间12。辐射屏蔽14被配置为根据安全标准在每个隔间中对其他隔间中生成的辐射提供足够屏蔽。对于其他隔间中生成的二次辐射,每个隔间被足够地屏蔽14。在每个隔间12中,具有患者支撑系统16,其包括支撑构件和固定构件20,用于支撑并空间地固定患者的进行辐射的靶标部分22。支撑构件可以是患者可坐在其上的水平可旋转的床18A,或患者可站立在其上的站立转盘18B或患者可坐在其上的坐转盘18C。在所有这些示例中,患者可绕基本垂直旋转轴23(图2)旋转。旋转轴23通常横切与该隔间相关的辐射束。EBRT system 10 includes a plurality of compartments 12 spaced apart from one another by radiation shields 14 . The radiation shield 14 is configured to provide adequate shielding in each compartment from radiation generated in other compartments according to safety standards. Each compartment is adequately shielded 14 from secondary radiation generated in other compartments. In each compartment 12 there is a patient support system 16 comprising a support member and a fixation member 20 for supporting and spatially fixing an irradiation target portion 22 of the patient. The support member may be a horizontally rotatable bed 18A on which the patient can sit, or a standing turntable 18B on which the patient can stand or a sitting turntable 18C on which the patient can sit. In all of these examples, the patient is rotatable about a substantially vertical axis of rotation 23 (FIG. 2). The axis of rotation 23 is generally transverse to the radiation beam associated with the compartment.

如图1中可看出,EBRT系统10的每个隔间12可包括不同的支撑构件(18A-18C)用于以与另一隔间不同的方位(例如,躺下、站立、坐下、或倚靠)支撑患者。这增加了该系统的多功能性并拓宽了其处理不同医疗应用的能力。As can be seen in Figure 1, each bay 12 of the EBRT system 10 may include a different support member (18A-18C) for use in a different orientation (e.g., lying down, standing, sitting, or leaning on) to support the patient. This increases the system's versatility and broadens its ability to handle different medical applications.

固定构件20可以是立体定向放射外科系统的标准固定部件,诸如夹、钉、螺丝等。The fixation member 20 may be a standard fixation component of a stereotaxic radiosurgery system, such as clips, nails, screws or the like.

EBRT系统10包括辐射源外壳24,其具有一个或多个辐射源26(例如Co60同位素),它能够朝向每个隔间12内的靶标部分22发射辐射束到隔间12内。可使用任意辐射,诸如但不限于重粒子辐射或光子辐射(伽马辐射)。EBRT system 10 includes a radiation source housing 24 having one or more radiation sources 26 (eg, Co 60 isotope) capable of emitting a radiation beam into each compartment 12 towards a target portion 22 within each compartment 12 . Any radiation may be used, such as but not limited to heavy particle radiation or photon radiation (gamma radiation).

每个隔间12包括一个或多个束成形器28(例如,圆柱准直器、多叶准直器、物理补偿器等),用于对发射至该隔间的辐射束成形。隔间内的所有准直器可操作以分别引导相应射束至隔间内的共同位置,待治疗靶标所定位的位置。隔间内的患者支撑和准直器可定制为特定应用,其中患者可站立、坐下、倚靠或躺下。准直器的分辨率和射野尺寸也可针对应用而优化,旋转轴23相对于源外壳24的位置也是如此。优化针对特定应用的相应隔间可允许诸如前列腺、肺部和胸部同时治疗。Each compartment 12 includes one or more beam shapers 28 (eg, cylindrical collimators, multi-leaf collimators, physical compensators, etc.) for shaping the radiation beam emitted to that compartment. All collimators within the compartment are operable to respectively direct respective beams to a common location within the compartment, where the target to be treated is located. Patient support and collimators within the compartment can be customized for specific applications where the patient can stand, sit, lean or lie down. The resolution and field size of the collimator can also be optimized for the application, as can the position of the axis of rotation 23 relative to the source housing 24 . Optimizing the respective compartments for a specific application allows simultaneous treatment of, for example, prostate, lung and chest.

在一个实施方式中,辐射源26是放射性源(例如,钴60源),其以多样性的方位(例如,全方位地)发射辐射。在另一实施方式中,辐射源26可以是线性准直器,其在期望方向上顺序地发射射束。例如,辐射束可通过电子枪生成,由加速结构以来自磁电管的微波脉冲加速,然后电子光学元件朝向辐射生成靶标在真空中偏转加速电子。每个靶标上的撞击电子生成被引导至不同隔间的相应辐射束。这些辐射束的快速排序与来自全方位辐射源的同时辐射在实践中是等效的。在另一实施方式中,辐射源外壳24旋转以使得辐射束被顺序地引导至不同隔间。In one embodiment, radiation source 26 is a radioactive source (eg, a cobalt-60 source) that emits radiation in a variety of orientations (eg, omnidirectional). In another embodiment, the radiation source 26 may be a linear collimator that emits beams sequentially in a desired direction. For example, a radiation beam may be generated by an electron gun, accelerated by an accelerating structure with microwave pulses from a magnetron, and then electron optics deflect the accelerated electrons in vacuum towards a radiation generating target. The impinging electrons on each target generate corresponding radiation beams that are directed to different compartments. Quick sequencing of these radiation beams is practically equivalent to simultaneous radiation from omnidirectional radiation sources. In another embodiment, the radiation source housing 24 is rotated such that the radiation beam is directed to the different compartments sequentially.

在另一实施方式中,提供一个或多个辐射拦截器30用于选择性地封堵被发射至隔间的辐射束。拦截器30可以是选择性地封堵射束的快门。可替代地,射束可以如现有技术的远距放射疗法钴60设备那样通过移动辐射源远离束成形器28来封堵。In another embodiment, one or more radiation interceptors 30 are provided for selectively blocking radiation beams emitted to the compartment. Interceptor 30 may be a shutter that selectively blocks the beam. Alternatively, the beam can be occluded by moving the radiation source away from the beam shaper 28 as in prior art teletherapy cobalt 60 devices.

可提供成像设备(未示出),诸如举例来说,荧光成像或超声设备,用于对由射束辐射的靶标成像。Imaging equipment (not shown) may be provided, such as, for example, fluorescence imaging or ultrasound equipment, for imaging the target irradiated by the beam.

Claims (6)

1. a kind of external beam radiotherapy system, it includes:
The multiple compartments being spaced apart from each other by radiation shield, each compartment include patient support system, it include supporting member and Fixing component, for the target moiety radiate of with supporting union space immobilized patients, and
Radiation source shell, it includes at least one radiation source, and the operable target moiety with the direction each compartment is launched Radiation beam is to the compartment, wherein each compartment includes beam shaper, for be emitted into the radiation beam of the compartment into Shape, and wherein described radiation shield is configured as the radiation according to safety standard in each compartment to being generated in other compartments Shielding enough is provided, and wherein described at least one radiation source is sent out in all directions towards each compartment by different passages Penetrate radiation beam,
Wherein described at least one radiation source includes linear accelerator, and its is operable with suitable in a vacuum towards generation target is radiated Accelerated electron beam is deflected to sequence, wherein each radiation generation target is configured to allow radiation by towards in the compartment Particular compartment guides.
2. external beam radiotherapy system according to claim 1, wherein the radiation beam is typically horizontal, and At least one compartment is wherein directed to, the patient support system is operable with around generally vertical rotary shaft rotation.
3. external beam radiotherapy system according to claim 1, wherein at least one radiation source can be around rotation Axle rotates and is configured as launching radiation towards the particular compartment in the compartment during at least one radiation source rotation Beam.
4. external beam radiotherapy system according to claim 1, wherein at least one radiation source is with diversity Orientation transmitting radiation beam, so as to launch radiation beam to each compartment simultaneously.
5. external beam radiotherapy system according to claim 1, in addition to radiation blocker, for selective shut-off At least one radiation beam is launched at least one compartment.
6. external beam radiotherapy system according to claim 1, wherein at least one supporting member is configured To support the patient in a compartment with the orientation different from another supporting member in another compartment.
CN201490001361.1U 2014-02-26 2014-02-26 External beam radiotherapy system Expired - Fee Related CN206792814U (en)

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JP2824363B2 (en) * 1992-07-15 1998-11-11 三菱電機株式会社 Beam supply device
US5433693A (en) * 1992-12-31 1995-07-18 Ott; Karl O. Neutron-capture therapy apparatus and method
DE602004011560T2 (en) * 2003-12-02 2009-02-05 Radinova Ab MORE ROOM RADIATION TREATMENT SYSTEM
DE102004025502B4 (en) * 2004-05-21 2006-12-28 Gesellschaft für Schwerionenforschung mbH Accelerator system for ion beam radiation therapy
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