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CN204207717U - Endoscope irradiation spectrum selection device and hyperspectral endoscope imaging system - Google Patents

Endoscope irradiation spectrum selection device and hyperspectral endoscope imaging system Download PDF

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CN204207717U
CN204207717U CN201420591311.5U CN201420591311U CN204207717U CN 204207717 U CN204207717 U CN 204207717U CN 201420591311 U CN201420591311 U CN 201420591311U CN 204207717 U CN204207717 U CN 204207717U
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light
endoscope
wavelength
dispersion element
spectral
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刘满林
刘俊
王翰林
安昕
张浠
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Foshan City Nanhai District Optomedic Technology Co ltd
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Abstract

The utility model discloses a hyper-spectral endoscope imaging system, including the light source, the selection device of illuminating spectrum, the endoscope, image processing unit, display element, the selection device of illuminating spectrum includes dispersive element, convergent lens, movable speculum, and each different wavelength light of dispersive element outgoing is thrown to movable speculum behind the convergent lens, through the removal of movable speculum, couples each wavelength light respectively to the incident plane of the light guide of electron endoscope. The utility model uses the principle of light dispersion, uses the wavelength selection device to simply and conveniently select the wavelength of the irradiated light, and obtains the irradiated spectrum of any spectral band from the near infrared to the visible light spectral range of the measured tissue in real time; the doctor can select the spectral image to be shot according to the condition of a patient and the optical characteristics of the pathological tissue, so that the integration of the atlas and the real-time spectral imaging of the in-vivo living tissue are realized.

Description

内窥镜照射光谱选择装置及超光谱内窥镜成像系统Endoscope irradiation spectrum selection device and hyperspectral endoscope imaging system

技术领域technical field

本实用新型涉及一种基于内窥镜的光谱成像医疗设备,具体涉及一种内窥镜多谱段照射光谱的选择装置,另外,本实用新型还涉及使用上述选择装置的超光谱内窥镜成像系统。The utility model relates to a spectral imaging medical device based on an endoscope, in particular to a selection device for endoscope multi-spectrum irradiation spectrum, and in addition, the utility model also relates to a hyperspectral endoscope imaging using the selection device system.

背景技术Background technique

光谱成像技术是光谱分析和光学成像技术的结合,可以同时获得生物组织的形态信息和生物组织在某一波长范围内的完整光谱数据。由于生物组织在不同的病理状态下具有独特的反射光谱、自发荧光光谱和诱发荧光光谱,所以对生物组织进行光谱成像并进行一定的量化分析,可以实现某些病理变化的早期诊断。特别是对肿瘤和其他疾病的发病机理、临床诊断、病情检测和疗效评估的研究有重要意义。Spectral imaging technology is a combination of spectral analysis and optical imaging technology, which can simultaneously obtain the morphological information of biological tissues and the complete spectral data of biological tissues in a certain wavelength range. Since biological tissues have unique reflectance spectra, autofluorescence spectra, and induced fluorescence spectra under different pathological conditions, spectral imaging of biological tissues and quantitative analysis can achieve early diagnosis of certain pathological changes. In particular, it is of great significance to the research on the pathogenesis, clinical diagnosis, disease detection and curative effect evaluation of tumors and other diseases.

目前在医疗领域中对组织进行光谱成像基本上都需要先进行样本的采集和制备,然后用成像光谱设备采集数据。这种方式不能对活体组织进行在体的光谱成像,极大的限制了光谱成像技术在疾病的早期诊断、治疗效果评价等领域的应用。At present, the spectral imaging of tissues in the medical field basically requires the collection and preparation of samples first, and then collects data with imaging spectral equipment. This method cannot perform in vivo spectral imaging on living tissues, which greatly limits the application of spectral imaging technology in the fields of early diagnosis of diseases and evaluation of treatment effects.

近年来有相关文献和专利提出了多光谱成像技术与内窥镜相结合的设备,在一定程度上实现了对活体组织的在体光谱成像。例如,奥林巴斯提出了一种窄带光谱成像(Narrow Band Imaging)内窥镜。该内窥镜利用易被血红蛋白吸收的两种波长的光(蓝色光:405nm~425nm/绿色光:540~560nm)来照射并进行成像,使粘膜表层的毛细血管和粘膜的细微结构得以强调表示。由于组织产生癌变时会导致病变处血管增多,毛细血管在粘膜表面形成的结构就会发生变化,利用这一点,窄带光谱成像内窥镜可以为癌症的早期发现提供有力的帮助。In recent years, relevant literature and patents have proposed a device combining multispectral imaging technology with an endoscope, which has realized in vivo spectral imaging of living tissues to a certain extent. For example, Olympus has proposed a narrow band spectral imaging (Narrow Band Imaging) endoscope. This endoscope uses light of two wavelengths (blue light: 405nm-425nm/green light: 540-560nm) that is easily absorbed by hemoglobin to irradiate and image the capillaries on the surface of the mucous membrane and the fine structure of the mucous membrane. . When the tissue becomes cancerous, the blood vessels in the lesion will increase, and the structure formed by the capillary on the mucosal surface will change. Taking advantage of this, the narrow-band spectral imaging endoscope can provide powerful help for the early detection of cancer.

又例如,奥林巴斯提出了一种自体荧光成像(Auto Fluorescence Imaging)内窥镜,该内窥镜利用组织的诱发荧光特性,使用蓝光(390nm~470nm)激发光照射到黏膜下层,使组织产生强荧光。荧光如果遇到发育异常的病灶(例如浅表血管的异常聚集或黏膜增厚),光线减少,荧光变弱。该内窥镜系统会将这些细微变化转换成色彩信息,使正常黏膜和病灶之间的细微区别得到强调,为诊断组织的病理变化提供依据。For another example, Olympus proposed an autofluorescence imaging (Auto Fluorescence Imaging) endoscope, which utilizes the induced fluorescence properties of tissues, and uses blue light (390nm-470nm) excitation light to irradiate the submucosa, making the tissue Produces strong fluorescence. If the fluorescence encounters abnormal developmental lesions (such as abnormal collection of superficial blood vessels or thickened mucosa), the light decreases and the fluorescence becomes weaker. The endoscope system will convert these subtle changes into color information, so that the subtle differences between normal mucosa and lesions can be emphasized, and provide a basis for diagnosing pathological changes in tissues.

中国专利CN 103340601 A提出一种基于内窥镜的多光谱成像系统和方法,该专利提出的设备提供了近红外和可见光光源,并使用多组滤波片进行滤光,从而获得与滤光片相对应的多光谱图像。Chinese patent CN 103340601 A proposes an endoscope-based multispectral imaging system and method. The device proposed in this patent provides near-infrared and visible light sources, and uses multiple sets of filters for filtering, so as to obtain The corresponding multispectral image.

上述奥林巴斯提出的窄带光谱成像内窥镜、自体荧光成像内窥镜、及专利CN 103340601 A提出“基于内窥镜的多光谱成像系统”通常都包括光源,用于提供近红外到可见光内全谱段的照明光;滤波片组合,用于在照明光中选择较窄谱段的光线耦合到内窥镜照射被检组织;内窥镜,拍摄被检组织在指定谱段照明光照射下的光谱图像;图像处理单元,将被检组织在各种谱段照明光的下的光谱图像进行图像融合和处理,获得组织的光谱图像;以及显示单元,对上述图像进行图像显示;这些设备可以在一定程度上实现对体内组织进行在体光谱成像。但是仍然存在其局限性。The narrow-band spectral imaging endoscope, autofluorescence imaging endoscope, and patent CN 103340601 A proposed by Olympus mentioned above usually include a light source for providing near-infrared to visible light Illuminating light of the full spectrum within; filter combination, used to select a narrower spectrum of light in the illuminating light and couple it to the endoscope to irradiate the examined tissue; endoscope, to photograph the examined tissue in the specified spectral band illuminated light The spectral image under the image; the image processing unit, which performs image fusion and processing on the spectral images of the inspected tissue under the illumination light of various spectral bands, and obtains the spectral image of the tissue; and the display unit, which performs image display on the above-mentioned images; these devices In vivo spectral imaging of tissues in vivo can be achieved to a certain extent. But there are still its limitations.

上述几个方案的共同点是利用经过滤波片滤光后的光源对组织进行照明,以获得与滤波片对应的照射光谱图像。或者使用单色激光器作为光源,以获得激光器波长相对应的光谱图像。The common point of the above-mentioned solutions is to use the light source filtered by the filter to illuminate the tissue, so as to obtain the illumination spectrum image corresponding to the filter. Or use a monochromatic laser as a light source to obtain a spectral image corresponding to the laser wavelength.

这种光谱图像的方式具有较大的局限性。一套设备中滤波片的数量决定了能采集到的组织的多光谱图像的光谱组成。例如奥林巴斯的窄带光谱成像内窥镜设备。该设备共有两组共计五种滤波片:R(600nm~700nm)、G(500nm~600nm)、B(400nm~500nm)滤波片组和Ga(540nm~560nm)、Ba(405nm~415nm)滤波片组,该设备只能获得组织的两种光谱图像。This way of spectral imagery has great limitations. The number of filters in a set of equipment determines the spectral composition of the multispectral image of tissue that can be collected. An example is Olympus' narrowband spectral imaging endoscopy device. The device has two groups of five filters in total: R (600nm~700nm), G (500nm~600nm), B (400nm~500nm) filter group and Ga (540nm~560nm), Ba (405nm~415nm) filter group, the device can only obtain two spectral images of tissue.

综上所述,目前的技术方案由于依赖滤波片或单色激光器,只能获得组织的极少几个特定的光谱图像。To sum up, the current technical solutions can only obtain very few specific spectral images of tissues due to the dependence on filters or monochromatic lasers.

实用新型内容Utility model content

针对上述方案缺点,本实用新型的目的在于提供一种内窥镜照射光谱的选择装置,可以简单方便的获取近红外到可见光光谱范围内任意谱段,用于内窥镜光谱成像。In view of the shortcomings of the above solutions, the purpose of this utility model is to provide a device for selecting the irradiation spectrum of an endoscope, which can simply and conveniently acquire any spectrum from near-infrared to visible light spectrum for endoscope spectral imaging.

本实用新型的另一个目的在于提供使用上述选择装置的超光谱内窥镜成像系统,可以获得被测组织近红外到可见光光谱范围内任意谱段的光谱图像。Another object of the present utility model is to provide a hyperspectral endoscopic imaging system using the above-mentioned selection device, which can obtain spectral images of any spectral segment from near-infrared to visible light spectral range of the measured tissue.

本实用新型的第一个目的通过以下的技术措施来实现:一种内窥镜照射光谱的选择装置,包括:The first purpose of the utility model is achieved through the following technical measures: a selection device for endoscope irradiation spectrum, comprising:

色散元件,用于将入射到色散元件上的可见光束按波长的不同进行色散,使出射光的角度或位置根据入射光波长分布;The dispersion element is used to disperse the visible light beam incident on the dispersion element according to different wavelengths, so that the angle or position of the outgoing light is distributed according to the wavelength of the incident light;

会聚透镜,会聚透镜的焦点位于可见光束与色散元件的入射点;A converging lens, the focal point of which is located at the incident point of the visible light beam and the dispersion element;

可运动反射镜,由驱动电路控制下进行一维运动;The movable mirror is controlled by the drive circuit for one-dimensional movement;

电子内窥镜的光导件,用于耦合输入不同波段的照射光谱;The light guide of the electronic endoscope is used to couple the irradiation spectrum of different bands;

色散元件出射的各个不同波长光经会聚透镜后投射到可运动反射镜,通过可运动反射镜的移动,将各波长光线分别耦合到电子内窥镜的光导件的入射面。Lights of different wavelengths emitted by the dispersing element are projected onto the movable reflector after passing through the converging lens, and the light of each wavelength is respectively coupled to the incident surface of the light guide of the electronic endoscope through the movement of the movable reflector.

优先的,所述色散元件为反射光栅。Preferably, the dispersion element is a reflective grating.

本实用新型的另一个目的通过以下的技术措施来实现:一种超光谱内窥镜成像系统,包括:光源,用于提供近红外到可见光内全谱段的照明光;照射光谱的选择装置,用于在照明光中选择任意指定谱段的光线耦合到内窥镜照射被检组织;内窥镜,拍摄被检组织在指定谱段照明光照射下的光谱图像;图像处理单元,将被检组织在各种谱段照明光的下的光谱图像进行图像融合和处理,获得组织的光谱图像;以及显示单元,对上述图像进行图像显示;Another object of the utility model is achieved through the following technical measures: a hyperspectral endoscopic imaging system, comprising: a light source for providing illumination light from the near-infrared to the full spectrum of visible light; a selection device for the irradiation spectrum, The light used to select any specified spectrum in the illumination light is coupled to the endoscope to irradiate the tissue to be inspected; the endoscope captures the spectral image of the tissue to be inspected under the illumination of the specified spectrum; the image processing unit performing image fusion and processing on the spectral images of the tissue under various spectral bands of illumination light to obtain the spectral image of the tissue; and a display unit for image displaying the above images;

其特征在于所述照射光谱的选择装置包括:It is characterized in that the selection device of the irradiation spectrum comprises:

色散元件,用于将入射到色散元件上的可见光束按波长的不同进行色散,使出射光的角度或位置根据入射光波长分布;The dispersion element is used to disperse the visible light beam incident on the dispersion element according to different wavelengths, so that the angle or position of the outgoing light is distributed according to the wavelength of the incident light;

会聚透镜,会聚透镜的焦点位于可见光束与色散元件的入射点;A converging lens, the focal point of which is located at the incident point of the visible light beam and the dispersion element;

可运动反射镜,由驱动电路控制下进行一维运动;The movable mirror is controlled by the drive circuit for one-dimensional movement;

电子内窥镜的光导件,用于耦合输入不同波段的照射光谱;The light guide of the electronic endoscope is used to couple the irradiation spectrum of different bands;

色散元件出射的各个不同波长光经会聚透镜后投射到可运动反射镜,通过可运动反射镜的移动,将各波长光线分别耦合到电子内窥镜的光导件的入射面。Lights of different wavelengths emitted by the dispersing element are projected onto the movable reflector after passing through the converging lens, and the light of each wavelength is respectively coupled to the incident surface of the light guide of the electronic endoscope through the movement of the movable reflector.

优先的,所述色散元件为反射光栅。Preferably, the dispersion element is a reflective grating.

优先的,所述光源包括:氙气灯和准直透镜,所述氙气灯发出的照明光经准直透镜准直成平行光输出投射到所述色散元件上。Preferably, the light source includes: a xenon lamp and a collimating lens, and the illumination light emitted by the xenon lamp is collimated by the collimating lens into parallel light output and projected onto the dispersion element.

进一步的,所述光源还包括用于改变通光孔径大小的可变光阑,所述准直透镜准直成的平行光经可变光阑后输出投射到所述色散元件上。Further, the light source also includes an iris diaphragm for changing the size of the clear aperture, and the parallel light collimated by the collimator lens is output and projected onto the dispersion element after passing through the iris diaphragm.

进一步的,所述图像处理单元中设有控制模块,用于分别触发控制所述可运动反射镜的驱动、内窥镜的拍摄、图像处理和光阑孔径调节。Further, the image processing unit is provided with a control module, which is used to respectively trigger and control the driving of the movable mirror, the shooting of the endoscope, the image processing and the adjustment of the diaphragm aperture.

本实用新型利用光的色散原理,使用波长选择装置可以简单、方便对照射光的波长进行选择,实时获得被测组织近红外到可见光光谱范围内任意谱段的照射光谱;医生可以根据病人的病情和病变组织的光学特性,选择需要拍摄的光谱图像,实现图谱合一、对体内活体组织的实时光谱成像;实现某些病理变化的早期诊断。特别是对肿瘤和其他疾病的发病机理、临床诊断、病情检测和疗效评估的研究有重要意义。The utility model utilizes the dispersion principle of light, and the wavelength selection device can simply and conveniently select the wavelength of the irradiated light, and obtain the irradiated spectrum of any spectrum from the near-infrared to the visible light spectrum of the measured tissue in real time; According to the optical characteristics of the diseased tissue, select the spectral image to be taken, realize the integration of the map and the real-time spectral imaging of the living tissue in the body; realize the early diagnosis of certain pathological changes. In particular, it is of great significance to the research on the pathogenesis, clinical diagnosis, disease detection and curative effect evaluation of tumors and other diseases.

附图说明Description of drawings

图1本实用新型系统原理组成框图;Fig. 1 composition block diagram of the utility model system principle;

图2本实用新型波长选择装置中选择不同波长的原理图。Fig. 2 is a schematic diagram of selecting different wavelengths in the wavelength selection device of the present invention.

具体实施方式Detailed ways

如图1为本实用新型的一个实例。如图1所示,本实施例的超光谱内窥镜成像系统包括:光源装置1,波长选择装置2,电子内窥镜3,图像处理器4,显示器5。Figure 1 is an example of the utility model. As shown in FIG. 1 , the hyperspectral endoscopic imaging system of this embodiment includes: a light source device 1 , a wavelength selection device 2 , an electronic endoscope 3 , an image processor 4 , and a display 5 .

其中,光源装置1用于提供照明光。照明装置1所提供的照明光,在近红外到可见光谱段内,光辐射强度随频率变化呈连续分布。在本实施例中,光源装置1包括:氙气灯7,其作用是发出照明光;准直透镜8,将氙气灯7发出的照明光准直成平行光;可变光阑9,可以在控制电路控制下,改变通光孔径的大小,从而实现控制输出照明光强度。Wherein, the light source device 1 is used for providing illumination light. The illuminating light provided by the illuminating device 1 has a continuous distribution of light radiation intensity as the frequency changes within the near-infrared to visible spectrum. In this embodiment, the light source device 1 includes: a xenon lamp 7, which functions to emit illuminating light; a collimating lens 8, which collimates the illuminating light emitted by the xenon lamp 7 into parallel light; Under the control of the circuit, the size of the light aperture is changed, so as to realize the control of the output illumination light intensity.

波长选择装置2的作用是,从照明光中选择指定谱段范围的光线,并将该谱段的光线会聚到电子内窥镜3的光导件12的入射面。波长选择装置2包括:色散元件9,会聚透镜10,可运动反射镜11和光导件12。色散元件9其作用为将入射到散射元件9上的光束按波长的不同进行色散,使出射光的角度或位置根据入射光波长分布;本实施例中可使用Thorlabs公司生产的GR50-0603反射光栅作为色散元件。会聚透镜10的前焦点位于照明光与色散元件的入射点;可运动反射镜11位于会聚透镜10和光导件12之间;可运动反射镜11的运动位置和会聚透镜10、光导件12之间的位置关系满足指定谱段范围的光经过会聚透镜10会聚、可运动反射镜11反射后光线聚焦到光导件12的端面上。本实施例中,可运动反射镜做一维平移运动;可运动反射镜的驱动电路可以是用单片机实现。The function of the wavelength selection device 2 is to select the light in a specified spectral range from the illumination light, and converge the light in the spectral range to the incident surface of the light guide 12 of the electronic endoscope 3 . The wavelength selection device 2 includes: a dispersion element 9 , a converging lens 10 , a movable mirror 11 and a light guide 12 . The role of the dispersion element 9 is to disperse the light beam incident on the scattering element 9 according to the wavelength, so that the angle or position of the outgoing light is distributed according to the wavelength of the incident light; in this embodiment, the GR50-0603 reflection grating produced by Thorlabs can be used as a dispersive element. The front focal point of the converging lens 10 is located at the incident point of the illuminating light and the dispersion element; the movable mirror 11 is located between the converging lens 10 and the light guide 12; the moving position of the movable reflector 11 is between the converging lens 10 and the light guide 12 The positional relationship of the light satisfying the specified spectral range is converged by the converging lens 10 , reflected by the movable mirror 11 , and the light is focused on the end surface of the light guide 12 . In this embodiment, the movable mirror performs one-dimensional translational movement; the driving circuit of the movable mirror can be realized by a single-chip microcomputer.

图2是波长选择装置3进行指定波长选择的原理示意图。根据光栅公式,间距为d的反射光栅,入射光以相对于光栅表面法线的入射角α入射,m级出射光相对于光栅表面法线的出射角θ与入射光波长λ的关系如下:FIG. 2 is a schematic diagram of the principle of selecting a specified wavelength by the wavelength selection device 3 . According to the grating formula, for a reflective grating with a pitch of d, the incident light is incident at an incident angle α relative to the normal of the grating surface, and the relationship between the outgoing angle θ of the m-level outgoing light relative to the normal of the grating surface and the wavelength λ of the incident light is as follows:

d(sin(θ)-sin(α))=mλd(sin(θ)-sin(α))=mλ

照明光中波长为λ1与波长为λ2的光线经过反射光栅后会以不同的角度出射。由于会聚透镜10的焦点位于照明光与反射光栅的入射点,波长λ1与波长为λ2的光线经过会聚透镜后,聚焦在不同的位置。若会聚透镜的焦距为f,波长λ1与波长为λ2的光线经过会聚透镜后会聚点的距离Δl为:In the illumination light, the light rays with wavelength λ 1 and wavelength λ 2 will exit at different angles after passing through the reflective grating. Since the focal point of the converging lens 10 is located at the incident point of the illumination light and the reflective grating, light rays with a wavelength of λ1 and a wavelength of λ2 are focused in different positions after passing through the converging lens. If the focal length of the converging lens is f, the distance Δl between the converging point of the light rays with wavelength λ 1 and wavelength λ 2 passing through the converging lens is:

Δl=f(tanθ1-tanθ2)Δl=f(tanθ 1 -tanθ 2 )

如图2所示,光导件12的入射面的直径为a,在一种状态下波长λ1的光线经过可运动反射镜11反射后,会聚到光导件12中心。若波长为λ2的光线经过会聚透镜后与波长λ1的会聚点的距离Δl大于1/2a时,则波长λ2的光线无法进入光导件12。在另一种状态下,可运动反射镜向右运动距离Δl,则波长λ2的光线会聚到光导件12中心,而波长λ1的光线无法进入光导件12。如此,可以通过控制可运动反射镜的位置,选择需要的波长耦合进入光导件12。As shown in FIG. 2 , the diameter of the incident surface of the light guide 12 is a. In one state, the light with wavelength λ1 is reflected by the movable mirror 11 and converges to the center of the light guide 12 . If the distance Δ1 between the light of wavelength λ2 and the converging point of wavelength λ1 after passing through the converging lens is greater than 1/2a, the light of wavelength λ2 cannot enter the light guide 12. In another state, if the movable reflector moves to the right by a distance Δl, the light with a wavelength of λ2 converges to the center of the light guide 12, while the light with a wavelength of λ1 cannot enter the light guide 12. In this way, desired wavelengths can be selected to be coupled into the light guide 12 by controlling the position of the movable mirror.

当需要的拍摄λ1、λ2….λn的光谱图像,具体可选用一个包括色散λ1、λ2….λn不同波段光的反射光栅,反射镜需要在一维平移运动n个位置点,这些不同波长和位置点需要事先调校对应并存储记录到控制模块和发射镜驱动电路中。When it is necessary to take spectral images of λ 1 , λ 2 .... λ n , a reflective grating including light in different bands of dispersion λ 1 , λ 2 .... λ n can be selected, and the mirror needs to move n positions in one-dimensional translation These different wavelengths and position points need to be adjusted in advance and stored and recorded in the control module and the mirror driving circuit.

上述色散元件还可采用如透射光栅、色散棱镜、分光光度计、光谱仪、声光偏转器或液晶可调滤光器等,这些元件的原理和上述反射光栅类同。可运动反射镜也可采用控制其转动来调节反射角度,将上述色散元件输出不同的波长耦合进入光导件。The above-mentioned dispersive element can also adopt transmission grating, dispersive prism, spectrophotometer, spectrometer, acousto-optic deflector or liquid crystal tunable filter, etc., and the principles of these elements are similar to the above-mentioned reflective grating. The movable mirror can also control its rotation to adjust the reflection angle, and couple the different wavelengths output by the dispersion element into the light guide.

电子内窥镜3作用是插入到体腔内并拍摄腔内组织的图像信息,由图像处理器4储存。The function of the electronic endoscope 3 is to insert into the body cavity and take image information of tissues in the cavity, which is stored by the image processor 4 .

图像处理器4作用是存储摄像元件上的电子图像,并将组织在一系列光谱照射下的图像进行合成,获得组织的高光谱分辨率的光谱图像。The role of the image processor 4 is to store the electronic images on the imaging element and synthesize the images of the tissues under a series of spectral irradiations to obtain spectral images of the tissues with high spectral resolution.

上述图像处理单元中设置控制模块,用于分别触发控制所述可运动反射镜的驱动、内窥镜的拍摄、图像处理和光阑孔径调节。The image processing unit is provided with a control module, which is used to respectively trigger and control the driving of the movable mirror, the shooting of the endoscope, the image processing and the adjustment of the diaphragm aperture.

具体协调控制的过程如下:医生根据病人的病情和组织的光学特征,设定需要的拍摄λ1、λ2….λn的光谱图像。控制模块向驱动电路发出控制信号,使可运动反射镜11移动到位置A,使波长λ1的光线耦合进入导光件12,并通过导光件12和电子内窥镜4,照射到被测组织上。电子内窥镜4收集在被测组织上反射光或诱发荧光,成像到摄像元件像面,并被图像处理器5储存为λ1图像。控制模块向驱动电路发出控制信号,使可运动反射镜11移动到位置B,使波长λ2的光线耦合进入导光件12,并通过导光件12和电子内窥镜3,照射到被测组织上。电子内窥镜3收集在被测组织上反射光或诱发荧光,成像到摄像元件像面,并被图像处理器4储存为λ2图像。如此循环,获得被测组织一组λ1、λ2….λn光谱图像。图像处理器将这组图像合成,获得被测组织在λ1、λ2….λn光谱内的合成光谱图像。并由显示器5显示。The specific coordinated control process is as follows: the doctor sets the required spectral images of λ 1 , λ 2 .... λ n according to the patient's condition and the optical characteristics of the tissue. The control module sends a control signal to the driving circuit, so that the movable mirror 11 moves to position A, so that the light of wavelength λ1 is coupled into the light guide 12, and irradiates the measured light through the light guide 12 and the electronic endoscope 4 organizationally. The electronic endoscope 4 collects the reflected light or induced fluorescence on the tissue under test, images it on the image plane of the imaging element, and stores it as a λ1 image by the image processor 5. The control module sends a control signal to the drive circuit, so that the movable mirror 11 moves to position B, so that the light with a wavelength of λ2 is coupled into the light guide 12, and irradiates the measured light through the light guide 12 and the electronic endoscope 3 organizationally. The electronic endoscope 3 collects the reflected light or induced fluorescence on the tissue under test, images it on the image plane of the imaging element, and stores it as a λ2 image by the image processor 4. In this way, a set of λ 1 , λ 2 . . . λ n spectral images of the measured tissue is obtained. The image processor synthesizes the group of images to obtain the synthesized spectral images of the measured tissue in the λ 1 , λ 2 . . . λ n spectrum. And displayed by display 5.

本实用新型不局限与上述具体实施方式,根据上述内容,按照本领域的普通技术知识和惯用手段,在不脱离本实用新型上述基本技术思想前提下,本实用新型还可以做出其它多种形式的等效修改、替换或变更,均落在本实用新型的保护范围之中。The utility model is not limited to the above-mentioned specific embodiments. According to the above content, according to the common technical knowledge and conventional means in this field, without departing from the above-mentioned basic technical ideas of the utility model, the utility model can also be made into other various forms. The equivalent modifications, replacements or alterations all fall within the protection scope of the present utility model.

Claims (7)

1. a selecting arrangement for endoscope's illumination spectra, is characterized in that comprising:
Dispersion element, carries out dispersion for the visible light beam that will incide on dispersion element by the difference of wavelength, the angle of emergent light or position is distributed according to lambda1-wavelength;
Collecting lens, the focus of collecting lens is positioned at the incidence point of visible light beam and dispersion element;
Movable reflecting mirror, is controlled down to carry out motion in one dimension by drive circuit;
The light guide therefor of fujinon electronic video endoscope, for the illumination spectra of the input different-waveband that is coupled;
Each different wavelengths of light of dispersion element outgoing projects movable reflecting mirror after collecting lens, by the movement of movable reflecting mirror, each wavelength light is coupled to respectively the incident end face of the light guide therefor of fujinon electronic video endoscope.
2. the selecting arrangement of a kind of endoscope according to claim 1 illumination spectra, is characterized in that: described dispersion element is reflecting grating.
3. a ultraphotic spectrum endoscopic imaging system, comprising: light source, for providing the illumination light of full spectral coverage in near-infrared to visible ray; The selecting arrangement of illumination spectra, specifies arbitrarily the coupling light of spectral coverage to irradiate tested tissue to endoscope for selecting in illumination light; Endoscope, takes and is testedly organized in the spectrum picture of specifying under spectral coverage illumination; Graphics processing unit, by tested be organized in various spectral coverage illumination light under spectrum picture carry out image co-registration and process, obtain tissue spectrum picture; And display unit, image display is carried out to above-mentioned image;
It is characterized in that the selecting arrangement of described illumination spectra comprises:
Dispersion element, carries out dispersion for the visible light beam that will incide on dispersion element by the difference of wavelength, the angle of emergent light or position is distributed according to lambda1-wavelength;
Collecting lens, the focus of collecting lens is positioned at the incidence point of visible light beam and dispersion element;
Movable reflecting mirror, is controlled down to carry out motion in one dimension by drive circuit;
The light guide therefor of fujinon electronic video endoscope, for the illumination spectra of the input different-waveband that is coupled;
Each different wavelengths of light of dispersion element outgoing projects movable reflecting mirror after collecting lens, by the movement of movable reflecting mirror, each wavelength light is coupled to respectively the plane of incidence of the light guide therefor of fujinon electronic video endoscope.
4. a kind of ultraphotic spectrum endoscopic imaging system according to claim 3, is characterized in that: described dispersion element is reflecting grating.
5. a kind of ultraphotic spectrum endoscopic imaging system according to claim 3, it is characterized in that: described light source comprises: xenon lamp and collimating lens, the illumination light that described xenon lamp sends is collimated into directional light output through collimating lens and projects on described dispersion element.
6. a kind of ultraphotic spectrum endoscopic imaging system according to claim 5, it is characterized in that: described light source also comprises the iris for changing clear aperature size, the directional light that described collimating lens is collimated into exports and projects on described dispersion element after iris.
7. a kind of ultraphotic spectrum endoscopic imaging system according to claim 3, it is characterized in that: in described graphics processing unit, be provided with control module, regulate for the shooting of the driving of respectively movable reflecting mirror described in trigging control, endoscope, image procossing and the aperture of the diaphragm.
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CN104352216A (en) * 2014-10-13 2015-02-18 佛山市南海区欧谱曼迪科技有限责任公司 Endoscope irradiation spectrum selection device and hyperspectral endoscope imaging system
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CN104352216A (en) * 2014-10-13 2015-02-18 佛山市南海区欧谱曼迪科技有限责任公司 Endoscope irradiation spectrum selection device and hyperspectral endoscope imaging system
CN106840392A (en) * 2015-12-03 2017-06-13 北京北方微电子基地设备工艺研究中心有限责任公司 Help device, spectral signal system and the semiconductor equipment of spectral signal collection
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US12126887B2 (en) 2019-06-20 2024-10-22 Cilag Gmbh International Hyperspectral and fluorescence imaging with topology laser scanning in a light deficient environment
US12228516B2 (en) 2019-06-20 2025-02-18 Cilag Gmbh International Image synchronization without input clock and data transmission clock in a pulsed hyperspectral, fluorescence, and laser mapping imaging system
US12267573B2 (en) 2019-06-20 2025-04-01 Cilag Gmbh International Controlling integral energy of a laser pulse in a hyperspectral, fluorescence, and laser mapping imaging system
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US12357162B2 (en) 2019-06-20 2025-07-15 Cilag Gmbh International Videostroboscopy of vocal cords with a hyperspectral, fluorescence, and laser mapping imaging system

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