CN1971341B - Method for manufacturing contact lens capable of correcting high-order aberration of human eyes - Google Patents

Abstract

The invention discloses a contact lens capable of correcting high-order aberration of human eyes and a manufacturing method thereof. The glasses are provided or prepared with phase microstructures or microstructure elements capable of correcting higher-order aberration of human eyes in the lenses, and the manufacturing method comprises the following steps: measuring aberration data of the human eye; calculating the three-dimensional refractive index distribution in the lens capable of correcting the higher-order aberration of the human eyes according to the aberration data and the diopter correction capability of the original lens; and processing the required three-dimensional refractive index distribution in the contact lens material by utilizing the focused ultrashort pulse laser beam. Compared with the prior art, the phase microstructure capable of correcting the higher-order aberration of the human eye is arranged or prepared in the lens, and the surface of the lens is still smooth, so that the cornea of the human eye is not stimulated, the wearing comfort is not influenced, and the cornea of the human eye is not damaged. In addition, the phase microstructure is arranged or prepared in the lens, so that the reduction or loss of the correction capability caused by pollution or abrasion of the phase microstructure is avoided.

Description

Contact lens capable of correcting high-order aberrations of the human eye

technical field

The invention relates to a contact lens, in particular to a contact lens capable of correcting high-order aberrations of human eyes. The invention also relates to a manufacturing method of a contact lens capable of correcting high-order aberrations of human eyes. the

Background technique

The decline of human eyesight seriously affects a person's normal life, so it must be corrected. Traditional vision correction is mainly achieved by wearing glasses or contact lenses, or through surgical treatment. The main corrections are low-order aberrations such as defocus and astigmatism. In recent years, the rapid development of wavefront sensing technology has made the accurate measurement of human eye high-order aberrations a reality, and also made the correction of human eye high-order aberrations possible. Dr. David Williams from the University of Rochester in the United States and Dr. Junzhong Liang from the University of Heidelberg in Germany believe that the correction of high-order aberrations plays an important role in improving the visual effect of the human eye after in-depth research. In recent years, the proposed high-order aberration correction methods of the human eye mainly include corneal laser correction (laserablation of cornea or wavefront guided LASIK), implantable endoscopic correction (intraocular lens), contact lens correction, phase plate correction (phase plate correction). )wait. Each of these methods has advantages and disadvantages. Corneal laser correction and implantable endoscopic technology are both surgical treatments, which have high risks; phase plates (frame glasses) are very sensitive to positional movement, and it is difficult to guarantee the corrective effect in actual use. Relatively speaking, contact lenses are safer than surgical treatment, and are not as sensitive to positional movement as phase plates (frame glasses), so they have broader application prospects. the

In the production of contact lenses, traditional mechanical methods cannot produce contact lenses that can correct high-order aberrations of the human eye. "Method for correcting high-order aberrations of the human eye" (Chinese Patent Application No. 200410009115.3, Publication No. CN1702494A, Publication Date: November 30, 2005) achieves high Correction of order aberrations. The US patent application "Method for producing anartificial ocular lens" (Method for producing anartificial ocular lens, publication number US2002/0154271 A1) uses laser beams to directly process a phase microstructure that corrects high-order aberrations of the human eye on the surface of contact lens materials. The disadvantage of the above two production methods is that the microstructure is located on the surface of the contact lens lens, which may irritate the cornea of the eye, affect the wearing comfort, and even damage the cornea; in addition, the microstructure located on the surface of the contact lens lens may also be damaged by surface contamination or friction and wear. and other factors, the high-order aberration correction function is lost. the

Contents of the invention

The technical problem to be solved by the present invention is to provide a contact lens capable of correcting high-order aberrations of the human eye. Reduced functionality or failure. Another technical problem to be solved by the present invention is to provide a method for manufacturing the above-mentioned contact lens capable of correcting high-order aberrations of the human eye. the

The technical solution adopted by the present invention to solve the technical problem is: a contact lens capable of correcting the high-order aberration of the human eye, including a lens, and the inside of the lens has a phase microstructure capable of correcting the high-order aberration of the human eye. the

The material of the lens is a single-layer transparent material with nonlinear optical effects (two-photon polymerization or other nonlinear effects). the

The lens can also be a multi-layer structure, wherein at least one middle layer is a transparent material with nonlinear optical effect. the

A method for making a contact lens capable of correcting high-order aberrations of the human eye, comprising the following steps:

(1) Measure the aberration data W(x, y) of the human eye;

(2) Calculate the three-dimensional refractive index distribution n ₀ (x, y, z) in a certain area inside the contact lens that can correct the high-order aberration of the human eye based on the aberration data of the human eye and the diopter correction ability of the original lens of the contact lens ;

(3) Use a focused ultrashort pulse laser beam to irradiate a certain area inside the contact lens material, and change the three-dimensional refraction of the area irradiated by the focused ultrashort pulse laser beam in the contact lens material through two-photon polymerization of the contact lens material or other nonlinear optical effects Rate distribution n(x, y, z), making it equal to the refractive index distribution n ₀ (x, y, z) calculated in step (2): n(x, y, z)=n ₀ (x, y ,z).

In the step (1), a human eye aberration measuring instrument based on a Hartmann wavefront sensor is used to measure the human eye aberration. the

The calculation of the three-dimensional refractive index distribution in the step (2) is through a mathematical formula $W(x,\mathrm{the\; y})=\underset{0}{\overset{L(x,\mathrm{the\; y})}{\∫}}\mathrm{\Δ}{\mathrm{no}}_0(x,\mathrm{the\; y}.z)\mathrm{dz}$ accomplish,

where L(x,y) represents the thickness of the contact lens material with the nonlinear optical effect at the (x,y) coordinates. the

The original lens of the contact lens in the steps (2) and (3) is a lens without dioptric aberration correction or a dioptric aberration corrected lens. the

The pulse width of the ultrashort pulse laser beam in the step (3) ranges from 10 ^-15 seconds (1 femtosecond) to 10 ^-9 seconds (1 nanosecond).

The ultrashort pulse laser beam in the step (3) is focused by a lens into the lens of the contact lens, and the focus position is located in the material of the contact lens with nonlinear optical effect. the

The formation of the three-dimensional refractive index distribution in the step (3) is realized by the two-photon polymerization of the contact lens material or other nonlinear optical effects. the

The three-dimensional refractive index distribution in the step (3) is formed by three-dimensionally scanning the position of the contact lens or the focus position of the focused laser beam or the relative position of the focus of the focused laser beam in the lens of the contact lens, and controlling the laser beam at each scanning position Power and irradiation time are achieved. the

After the step (3) is completed, steps (1) to (3) can be repeated for correction based on the actual visual correction effect until a satisfactory visual correction effect is obtained. the

The principle of the present invention is: the material with nonlinear optical effect used in contact lenses is irradiated by a focused ultrashort pulse laser beam, when the laser beam power density in the area near the focus of the focused ultrashort pulse laser beam reaches or exceeds a certain value , the lens material in this region has a refractive index change due to two-photon polymerization or other nonlinear optical effects, thereby changing the optical phase in this region. Since the refractive index change at a certain position in the material is related to the nonlinear optical properties of the material, the power density of the laser beam at this position, and the irradiation time, etc., the relative position of the focus of the focused laser beam in the contact lens is determined by three-dimensional scanning. By controlling the irradiation power and irradiation time of the laser beam at each scanning position, a three-dimensional refractive index distribution with a specific shape can be formed inside the contact lens material. When the three-dimensional refractive index distribution formed inside the contact lens material matches the measured aberration data of the human eye, the purpose of correcting the high-order aberration of the human eye can be achieved. the

Compared with the prior art, the present invention arranges the phase microstructure (or microstructure element) capable of correcting the high-order aberrations of the human eye inside the lens of the contact lens, while the surface of the lens is still smooth, so it will not affect the Irritation to the cornea of the human eye will not affect the wearing comfort, and of course it will not cause damage to the cornea. In addition, the arrangement of the phase microstructure inside the lens also avoids the reduction or loss of correction ability due to the contamination or wear of the phase microstructure. the

Description of drawings

The present invention will be further described below in conjunction with the accompanying drawings and embodiments. the

Fig. 1 is the schematic diagram of the embodiment of a kind of single-layer lens structure of the contact lens that can correct human eye high-order aberration of the present invention;

Fig. 2 is the schematic diagram of the embodiment of a kind of multi-layer lens structure (here is three-layer structure) of the contact lens that can correct human eye high-order aberration of the present invention;

FIG. 3 is a schematic diagram of an embodiment of a device used to manufacture a contact lens capable of correcting high-order aberrations of the human eye according to the present invention. the

Detailed ways

As shown in Figure 1, the lens 2 of the contact lens is a single-layer structure, and the material of the lens 2 is a material (usually a polymer material) with a nonlinear optical effect. Phase Microstructures for Higher-Order Aberrations 1. the

As shown in Figure 2, the lens of this contact lens is a three-layer structure, and the material of the middle layer 3 is a material (usually a polymer material) with a nonlinear optical effect, and the upper and lower layers can be other materials that do not have a nonlinear optical effect. contact lens material. A phase microstructure 1 capable of correcting high-order aberrations of the human eye is provided inside the intermediate layer 3 . Of course, the lens of the contact lens can also have a more layered structure, as long as one of the middle layers is a material with nonlinear optical effects, and the phase microstructure 1 that can correct the high-order aberrations of the human eye is set on this layer. The middle layer can be made of materials with nonlinear optical effects. the

A device for making a contact lens capable of correcting high-order aberrations of the human eye is shown in Figure 3, which includes an ultrashort pulse laser light source 4, a high-speed optical shutter 5, a variable power attenuator 6, and a beam steering mirror 7. Focusing lens 8, electronically controlled three-dimensional stage 10, computer 11 and human eye aberration measuring instrument 12. Wherein, the human eye aberration measuring instrument 12 is connected with the computer 11, and the human eye aberration data measured by the human eye aberration measuring instrument 12 can be sent to the computer 11; the high-speed optical shutter 5 and the variable power attenuator 6 are connected with the computer 11 respectively , can be controlled by computer 11. the

The steps of using the device to make a contact lens capable of correcting high-order aberrations of the human eye are as follows:

(1) Utilize the human eye aberration measuring instrument 12 to accurately measure the aberration W (x, y) of the human eye, and input the measurement results into the computer 11. Human eye aberration measuring instrument for front sensor;

(2) The computer calculates the three-dimensional refractive index distribution in a certain area inside the contact lens that can correct the high-order aberration of the human eye based on the aberration data of the human eye and the diopter correction ability of the original lens of the contact lens. The calculation of the refractive index distribution by mathematical formula $W(x,\mathrm{the\; y})=\underset{0}{\overset{L(x,\mathrm{the\; y})}{\∫}}\mathrm{\Δ}{\mathrm{no}}_0(x,\mathrm{the\; y},z)\mathrm{dz}$ Realization, where L(x, y) represents the contact lens material thickness with nonlinear optical effect at (x, y) coordinates. In the actual production process, the internal refractive index of the contact lens can be independent of the coordinate z within a certain thickness L(x, y), so that Δn ₀ (x, y)=W(x, y)/L(x, y );

(3) The lens 9 to be processed is placed on the electronically controlled three-dimensional stage 10, the output beam 13 of the ultrashort pulse laser light source 4 controls the irradiation time through the high-speed optical shutter 5, and the variable power attenuator 6 controls the irradiation power and beam After the turning mirror 7 changes direction, it is focused by the focusing lens 8 to the inside of the contact lens lens 9 placed on the electronically controlled three-dimensional stage 10, and the focal point is located in the contact lens material with nonlinear optical effect. Through the two-photon polymerization of the contact lens material or other nonlinear optical effects, the refractive index of the area irradiated by the focused ultrashort pulse laser beam in the contact lens material is changed, and the three-dimensional scanning of the lens position is realized by moving the position of the stage 10 in three dimensions. The three-dimensional refractive index distribution is obtained in the contact lens material, making it consistent with the refractive index distribution calculated in step (2), thereby achieving the purpose of correcting the high-order aberration of the human eye. The high-speed optical shutter 5, the variable power attenuator 6 and the electronically controlled three-dimensional stage 10 are controlled by a computer 11; In actual operation, the three-dimensional refractive index distribution can also be realized by two-dimensionally scanning the position of the laser beam and using a one-dimensional stage to move the position of the mirror longitudinally. the

In the process of processing, the original lens of the contact lens used can be a lens that does not correct diopter aberration, or a lens that corrects diopter aberration. After processing according to the above steps, the above steps can be repeated according to the actual visual correction effect until a satisfactory visual correction effect is obtained. the

Claims (5)

1. The manufacture method of the contact lens capable of correcting the high-order aberration of the human eye, comprising an eyeglass, is characterized in that: the inside of the eyeglass has a phase microstructure capable of correcting the high-order aberration of the human eye; the material of the eyeglass has A single-layer transparent material with a nonlinear optical effect; the lens is a multilayer structure, wherein at least one middle layer is a transparent material with a nonlinear optical effect, and the steps of making the contact lens capable of correcting high-order aberrations of the human eye are as follows : (1.1) Prepare a device for making contact lenses capable of correcting high-order aberrations of the human eye, which includes an ultrashort pulse laser light source (4), a high-speed optical shutter (5), a variable power attenuator (6), and a beam steering Mirror (7), focusing lens (8), electronically controlled three-dimensional stage (10), computer (11) and human eye aberration measuring instrument (12), wherein, human eye aberration measuring instrument (12) and computer (11) is connected, and the human eye aberration data that human eye aberration meter (12) measures is sent into computer (11); High-speed optical shutter (5) and variable power attenuator (6) link to each other with computer (11) respectively , is controlled by computer (11); (1.2) Utilize the human eye aberration measuring instrument (12) to accurately measure the aberration W (x, y) of the human eye, and input the measurement result into the computer (11), the human eye aberration measuring instrument (12) Using the human eye aberration measuring instrument based on the Hartmann wavefront sensor; (1.3) The computer (11) calculates the three-dimensional refractive index distribution in a certain area inside the contact lens that can correct the high-order aberration of the human eye according to the aberration data of the human eye and the diopter correction ability of the original lens of the contact lens. Distributions are calculated through mathematical formulas

Realize, where L(x, y) represents the thickness of the contact lens material with nonlinear optical effect at the (x, y) coordinates, in the actual preparation process, the internal refractive index of the contact lens can be made within a certain thickness L(x, y ) has nothing to do with the coordinate z, so that Δn ₀ (x, y)=W(x, y)/L(x, y); (1.4) Place the lens (9) to be processed on the electronically controlled three-dimensional stage (10), and the output beam (13) of the ultrashort pulse laser light source (4) controls the irradiation time through the high-speed optical shutter (5). The variable power attenuator (6) controls the irradiation power, and the beam turns to the reflector (7) to change the direction and then is focused by the focusing lens (8) to the inside of the contact lens lens (9) placed on the electronically controlled three-dimensional stage (10). , the focus position is located in the contact lens material with nonlinear optical effect, the refractive index of the area irradiated by the focused ultrashort pulse laser beam in the contact lens material is changed through the two-photon polymerization of the contact lens material, and the three-dimensional moving stage ( 10) The position of the lens is scanned three-dimensionally, and the three-dimensional refractive index distribution is obtained in the contact lens material, so that it is consistent with the refractive index distribution calculated in step (1.3), so as to achieve the purpose of correcting the high-order aberration of the human eye. The optical shutter (5), the variable power attenuator (6) and the electronically controlled three-dimensional stage (10) are controlled by a computer (11); by moving the electronically controlled three-dimensional stage (10) to control the focus of the laser on the contact lens The position of eyeglass (9). 2. The manufacturing method of a contact lens capable of correcting high-order aberrations of the human eye according to claim 1, wherein the original lens of the contact lens is a lens that does not correct diopter aberration or a lens that corrects diopter aberration. 3. The manufacturing method of contact lenses capable of correcting high-order aberrations of the human eye according to claim 1, wherein the pulse width range of the ultrashort pulse laser beam is between ^10-15 seconds- ^10-9 seconds between. 4. The manufacturing method of a contact lens capable of correcting high-order aberrations of the human eye according to claim 1, characterized in that: the formation of the three-dimensional refractive index distribution is performed by three-dimensionally scanning the position of the contact lens or the focus position of the focused laser beam or Focusing on the relative position of the focal point of the laser beam in the lens of the contact lens, and controlling the laser beam power and irradiation time at each scanning position is achieved. 5. The method for making contact lenses capable of correcting high-order aberrations of the human eye according to claim 1, characterized in that: after completing the step (1.4), repeat steps (1.2) to ( 1.4) Make corrections until a satisfactory visual correction effect is obtained.

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