CN1969941A - Fox immunity enhancer - Google Patents
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Abstract
本发明涉及一种狐免疫增强剂，属于动物营养技术领域。每100克产品含有大豆粉20～30克、鱼粉10～15克、果寡糖3～6克、异麦芽寡糖1～5克、芽孢杆菌2～5克、双歧杆菌3～6克、乳酸菌4～7克、酵母菌3～6克、黄芪1～3克、党参1.5～4克、大豆卵磷脂2～5克、DL－蛋胺酸0.5～1.0克、L－赖胺酸0.3～0.5克、复合维生素0.5～2.0克、磷酸氢钙1.0～2.0g，其余为玉米粉。本发明能有效抑制蓝狐、银狐肠道内有害菌的生长，增加有益菌数量，调理肠道微生态平衡，增强机体免疫力，促进蓝狐、银狐肠道内源性消化酶的分泌，提高氨基酸、糖类、脂肪酸及各种矿物质的吸收利用率，提高狐人工养殖的经济效益。The invention relates to a fox immune enhancer and belongs to the technical field of animal nutrition. Every 100 grams of the product contains 20-30 grams of soybean powder, 10-15 grams of fish meal, 3-6 grams of fructo-oligosaccharides, 1-5 grams of isomalto-oligosaccharides, 2-5 grams of Bacillus, 3-6 grams of Bifidobacteria, 4-7 grams of lactic acid bacteria, 3-6 grams of yeast, 1-3 grams of astragalus, 1.5-4 grams of Codonopsis pilosula, 2-5 grams of soybean lecithin, 0.5-1.0 grams of DL-methionine, 0.3-0.3 grams of L-lysine 0.5 g, 0.5-2.0 g of multivitamins, 1.0-2.0 g of calcium hydrogen phosphate, and the rest is corn flour. The invention can effectively inhibit the growth of harmful bacteria in the intestines of blue foxes and silver foxes, increase the number of beneficial bacteria, regulate the micro-ecological balance of the intestines, enhance the immunity of the body, promote the secretion of endogenous digestive enzymes in the intestinal tracts of blue foxes and silver foxes, and improve the The absorption and utilization rate of amino acids, sugars, fatty acids and various minerals can improve the economic benefits of fox artificial breeding.
Description
技术领域technical field
本发明涉及一种狐免疫增强剂，用于蓝狐、银狐养殖时调节肠道微生态平衡，增加蓝狐、银狐免疫机能及生产性能，提高人工养殖的经济效益。属于动物营养技术领域。The invention relates to a fox immune enhancer, which is used for adjusting the intestinal micro-ecological balance during blue fox and silver fox breeding, increasing the immune function and production performance of blue fox and silver fox, and improving the economic benefits of artificial breeding. The invention belongs to the technical field of animal nutrition.
背景技术Background technique
我国1956年从原苏联引进蓝狐(Alopex lagopus)、银黑狐(Vulpes vulpes)，在黑龙江、吉林、辽宁、内蒙古等地创建饲养场，标志着我国养狐业发展的开端。九十年代中期，国际毛皮市场处于低靡状态，直接影响我国毛皮市场价格。由于国内蓝狐饲养业中主要采用隔离笼养方法，因长期近亲繁殖，产生大量近交系，导致品种性状退化，个体小毛绒质量差，价格偏低，失去国际裘皮市场竞争的能力。饲料的组成及其营养价值、饲料的利用、添加剂的使用等诸多营养因素同样制约着我国养狐业的发展。因此有关狐营养学方面的研究，尤其是狐饲料及其添加剂的使用成为养狐业亟待解决的问题。my country introduced blue fox (Alopex lagopus) and silver black fox (Vulpes vulpes) from the former Soviet Union in 1956, and established farms in Heilongjiang, Jilin, Liaoning, Inner Mongolia and other places, marking the beginning of the development of my country's fox breeding industry. In the mid-1990s, the international fur market was in a sluggish state, which directly affected the price of my country's fur market. Since the domestic blue fox breeding industry mainly adopts the method of isolated cage breeding, a large number of inbred lines are produced due to long-term inbreeding, resulting in the degradation of breed traits, poor quality of individual small plush, low prices, and the loss of the ability to compete in the international fur market. The composition of feed and its nutritional value, the utilization of feed, the use of additives and many other nutritional factors also restrict the development of my country's fox breeding industry. Therefore, the research on fox nutrition, especially the use of fox feed and its additives has become an urgent problem to be solved in the fox industry.
人工养殖条件下的蓝狐饲料及其饲养方式与自然条件下放养有很大差别。狐系食肉动物，其基础日粮是以动物性饲料为主，同时配合些植物性饲料以及维生素、矿物质、微量元素等添加饲料。动物性饲料主要包括鱼类、家畜禽的肉类及其副产品、乳品和蛋类等。植物性饲料主要包括各种谷物、油料作物和各种蔬菜等。维生素有Va，Vc，Ve和复合维生素等。矿物质主要包括骨粉、食盐、钙、磷、铁、锌、铜等。蓝狐在各生物学时期对营养需求量不同，因此各生物学时期饲养要求也不同。靳世厚等(经济动物学报，1998，2：10-13)对狐日粮结构、消化代谢指标进行研究测定，提出了狐在各生物学时期的标准日粮组成及其主要营养指标的推荐值，而有关狐用复合型饲料添加剂的研究与应用国内外报道较少。近年来，随着国内外裘皮市场的好转，以及蓝狐引种人工授精改良技术的运用，我国养狐业发展很快，养狐业给国家带来很大的社会效益和经济效益，在很多地区已成为农民脱贫致富的好项目，狐存栏数量逐年扩大，前景可观。在狐养殖规模日益扩大的形势下，广大养殖户都希望使用高效、低成本的狐专用饲料，同时也希望能拥有一种促进生长发育速度、提高生产性能的综合性狐用饲料添加剂。目前市场上出售的饲料添加剂，大多是畜禽所用，而没有狐用饲料添加剂。养殖者常常购买畜禽用的复合酶添加剂等，以谋求达到提高养殖经济效益之目的。由于狐的生理特点与畜禽差别较大，饲料的组成及营养指标亦具有特殊性，因而畜禽所用饲料添加剂对狐所起的作用不大，这就需要一种适合狐生理特点的复合型饲料添加剂，以便进一步提高养殖的经济效益。The feed and feeding methods of blue foxes under artificial breeding conditions are quite different from those under natural conditions. The fox is a carnivore. Its basic diet is mainly animal feed, and at the same time, it is combined with some plant feed and supplementary feed such as vitamins, minerals, and trace elements. Animal feed mainly includes fish, livestock and poultry meat and its by-products, dairy products and eggs. Vegetable feed mainly includes various grains, oil crops and various vegetables. Vitamins include Va, Vc, Ve and multivitamins. Minerals mainly include bone meal, salt, calcium, phosphorus, iron, zinc, copper, etc. Blue foxes have different nutritional requirements in each biological period, so the feeding requirements are also different in each biological period. Jin Shihou et al. (Acta Economic Zoology, 1998, 2:10-13) studied and measured the diet structure and digestion and metabolism indicators of foxes, and proposed the standard diet composition and the recommended values of main nutritional indicators for foxes in various biological periods. However, there are few domestic and foreign reports on the research and application of compound feed additives for foxes. In recent years, with the improvement of the fur market at home and abroad, and the application of improved artificial insemination technology for the introduction of blue foxes, the fox breeding industry in my country has developed rapidly, and the fox breeding industry has brought great social and economic benefits to the country. In many areas It has become a good project for farmers to get rid of poverty and become rich. The number of foxes on hand is expanding year by year, and the prospect is promising. Under the situation that the scale of fox breeding is expanding day by day, the majority of farmers hope to use high-efficiency and low-cost fox-specific feed, and also hope to have a comprehensive fox-use feed additive that can promote growth and development and improve production performance. Most of the feed additives currently on the market are used for livestock and poultry, but there are no feed additives for foxes. Breeders often purchase compound enzyme additives for livestock and poultry in order to achieve the purpose of improving the economic efficiency of breeding. Because the physiological characteristics of foxes are quite different from those of livestock and poultry, and the composition and nutritional indicators of the feed are also particular, the feed additives used by livestock and poultry have little effect on foxes. This requires a compound type suitable for the physiological characteristics of foxes. Feed additives in order to further improve the economic benefits of farming.
益生元是指一种非消化性食物成分，能选择性促进肠内有益菌群的活性或生长繁殖，起到增进宿主健康和促生长的作用。寡糖不被有害的细菌分解和利用，功能性寡糖可以作为一种生长代谢的营养物质被肠道中的有益菌群(双歧杆菌、乳酸菌等)选择性地加以利用，促进有益菌生长，达到调整菌群的目的。近年来，我国研究发现，黄芪、党参等除可增强机体免疫力外，还可促进双歧杆菌、乳酸菌的生长，已经具备益生元的作用，一些中草药制剂也可作为益生元。益生元有许多优越性，不存在保持活菌数的技术难关，稳定性强，有效期长，不仅可促进有益菌群生长，而且还可提高机体的免疫功能。Prebiotics refer to a non-digestible food ingredient that can selectively promote the activity or growth and reproduction of beneficial bacteria in the intestines, and play a role in improving the health and growth of the host. Oligosaccharides are not decomposed and utilized by harmful bacteria. Functional oligosaccharides can be used as a nutrient for growth and metabolism by the beneficial bacteria in the intestine (bifidobacteria, lactic acid bacteria, etc.) to selectively utilize them to promote the growth of beneficial bacteria. To achieve the purpose of adjusting the flora. In recent years, research in my country has found that astragalus and codonopsis can not only enhance the body's immunity, but also promote the growth of bifidobacteria and lactic acid bacteria. They already have the effect of prebiotics, and some Chinese herbal preparations can also be used as prebiotics. Prebiotics have many advantages. There is no technical difficulty in maintaining the number of viable bacteria. They are stable and have a long validity period. They can not only promote the growth of beneficial bacteria, but also improve the immune function of the body.
益生素制剂均属于高效、无毒、无副作用的活性添加剂，能够促进畜禽的生长发育速度，提高畜禽的生产性能及免疫机能(Nelson et al，Scott Med J.2006，51(4)：5-9.)。益生素制剂中的有益微生物进入动物机体后，与有害菌争夺氧、附着位点和营养系，竞争性地抑制有害菌的生长，从而调节肠内菌群趋于正常。Toit等(International Journal of Food Microbiology，1998，40：93-104)发现益生素微生物代谢产生的有机酸及溶菌酶，降低肠内的pH值，杀灭不耐酸的有害菌和潜在的病原菌。微生态制剂能在动物肠道内产生各种消化酶，提高饲料利用率，从而调整和提高畜禽各器官的生理功能，促进畜禽生长，增加产蛋和产奶量，提高生产性能。目前寡聚糖等益生元物质及乳酸菌、酵母菌、双歧杆菌等益生素制剂己在畜禽及水产动物养殖中广泛应用，并取得了很大的社会效益和经济效益，但二者在野生经济动物养殖方面的研究和应用均未在国内系统展开。Prebiotic preparations are active additives with high efficiency, non-toxicity and no side effects, which can promote the growth and development speed of livestock and poultry, and improve the production performance and immune function of livestock and poultry (Nelson et al, Scott Med J.2006, 51 (4): 5-9.). After the beneficial microorganisms in the prebiotic preparation enter the animal body, they compete with harmful bacteria for oxygen, attachment sites and nutrient systems, and competitively inhibit the growth of harmful bacteria, thereby regulating the intestinal flora to tend to normal. Toit et al. (International Journal of Food Microbiology, 1998, 40:93-104) found that the organic acids and lysozyme produced by the metabolism of probiotic microorganisms can reduce the pH value of the intestines and kill acid-resistant harmful bacteria and potential pathogenic bacteria. Probiotics can produce various digestive enzymes in the intestinal tract of animals to improve feed utilization, thereby adjusting and improving the physiological functions of various organs of livestock and poultry, promoting the growth of livestock and poultry, increasing egg and milk production, and improving production performance. At present, prebiotic substances such as oligosaccharides and prebiotic preparations such as lactic acid bacteria, yeast, and bifidobacteria have been widely used in livestock, poultry and aquatic animal breeding, and have achieved great social and economic benefits. The research and application of economic animal breeding have not been carried out systematically in China.
发明内容Contents of the invention
本发明的目的在于针对现有技术的不足，提供一种狐免疫增强剂，用于蓝狐、银狐养殖时，能促进肠道内有益菌的生长、抑制有害菌的大量繁殖，调节肠道微生态平衡，提高肠道对蛋白质、脂肪、糖类等营养成分的吸收及利用，有效增加蓝狐、银狐免疫机能及生产性能，提高人工养殖的经济效益。The purpose of the present invention is to address the deficiencies in the prior art, to provide a fox immune enhancer, which can promote the growth of beneficial bacteria in the intestinal tract, inhibit the large-scale reproduction of harmful bacteria, and regulate intestinal microbiota. Ecological balance, improve intestinal absorption and utilization of protein, fat, sugar and other nutrients, effectively increase the immune function and production performance of blue fox and silver fox, and improve the economic benefits of artificial breeding.
为实现这样的目的，本发明根据狐肠道内菌类的组成特点，以玉米粉、鱼粉作为载体，采用果寡糖、异麦芽寡糖、双歧杆菌、乳酸菌、酵母菌、黄芪、党参、DL-蛋胺酸、L-赖胺酸、复合维生素、及多种矿物质等复合添加的方式，采用科学的配制加工方法研制而成。产品含有丰富的钙、磷、维生素、氨基酸等营养物质，能够充分适应蓝狐、银狐生长发育的营养需求。本发明的产品特别加入果寡糖、异麦芽寡糖、双歧杆菌、乳酸菌、酵母菌等外源性有益菌类及黄芪、党参中草药成分，不仅增加狐肠道内有益菌的数量，维持有益菌的种群优势，有效抑制有害菌的滋生，提高机体免疫力，为幼狐的机体健康打下良好基础。同时帮助成体狐提高消化代谢能力，有利于提高氨基酸、糖类、脂肪酸及各种矿物质的利用率。In order to achieve such a purpose, the present invention uses corn flour and fish meal as carriers, and uses fructooligosaccharides, isomaltooligosaccharides, bifidobacteria, lactic acid bacteria, saccharomyces, astragalus, Codonopsis pilosula, DL - Methionine, L-lysine, multivitamins, and various minerals are added in a way that is developed by scientific preparation and processing methods. The products are rich in calcium, phosphorus, vitamins, amino acids and other nutrients, which can fully meet the nutritional needs of the growth and development of blue foxes and silver foxes. The product of the present invention is specially added with exogenous beneficial bacteria such as fructooligosaccharide, isomaltooligosaccharide, bifidobacterium, lactic acid bacteria, yeast and Chinese herbal medicine components of Astragalus membranaceus and Codonopsis pilosula, which not only increases the number of beneficial bacteria in the intestinal tract of foxes, but also maintains the beneficial bacteria The population advantage can effectively inhibit the growth of harmful bacteria, improve the body's immunity, and lay a good foundation for the body health of young foxes. At the same time, it helps adult foxes improve their digestion and metabolism, which is conducive to improving the utilization rate of amino acids, sugars, fatty acids and various minerals.
本发明的营养性狐免疫增强剂(每100克)具体包含如下成分：Nutritional fox immune enhancer of the present invention (every 100 grams) specifically comprises following composition:
大豆粉20～30克，鱼粉10～15克，果寡糖3～6克，异麦芽寡糖1～5克，芽孢杆菌2～5克，双歧杆菌3～6克，乳酸菌4～7克，酵母菌3～6克，黄芪1～3克，党参1.5～4克，大豆卵磷脂2～5克，DL-蛋胺酸0.5～1.0克，L-赖胺酸0.3～0.5克，复合维生素0.5～2.0克，磷酸氢钙1.0～2.0g，用玉米粉调制总量至100g。20-30 grams of soybean powder, 10-15 grams of fish meal, 3-6 grams of fructo-oligosaccharides, 1-5 grams of isomalto-oligosaccharides, 2-5 grams of Bacillus, 3-6 grams of Bifidobacteria, 4-7 grams of lactic acid bacteria , 3-6 grams of yeast, 1-3 grams of astragalus, 1.5-4 grams of Codonopsis pilosula, 2-5 grams of soybean lecithin, 0.5-1.0 grams of DL-methionine, 0.3-0.5 grams of L-lysine, multivitamins 0.5 to 2.0 grams, 1.0 to 2.0 grams of calcium hydrogen phosphate, and the total amount is adjusted to 100 grams with corn flour.
优选的狐免疫增强剂(1)(每100克)含有如下成分：The preferred fox immune enhancer (1) (per 100 grams) contains the following ingredients:
大豆粉25克，鱼粉12克，果寡糖5克，异麦芽寡糖3克，芽孢杆菌3克，双歧杆菌4克，乳酸菌5克，酵母菌5克，黄芪2克，党参3克，大豆卵磷脂4克，DL-蛋胺酸0.8克，L-赖胺酸0.4克，复合维生素1.5克，磷酸氢钙1.2g，用玉米粉调制总量至100g。25 grams of soybean powder, 12 grams of fish meal, 5 grams of fructooligosaccharides, 3 grams of isomaltooligosaccharides, 3 grams of bacillus, 4 grams of bifidobacteria, 5 grams of lactic acid bacteria, 5 grams of yeast, 2 grams of astragalus, 3 grams of codonopsis, 4 grams of soybean lecithin, 0.8 grams of DL-methionine, 0.4 grams of L-lysine, 1.5 grams of multivitamins, 1.2 grams of calcium hydrogen phosphate, and the total amount is adjusted to 100 grams with corn flour.
优选的狐免疫增强剂(2)(每100克)含有如下成分：Preferred fox immune enhancer (2) (every 100 grams) contains following composition:
大豆粉28克，鱼粉14克，果寡糖6克，异麦芽寡糖4克，芽孢杆菌4克，双歧杆菌5克，乳酸菌6克，酵母菌6克，黄芪2.8克，党参3.5克，大豆卵磷脂4.5克，DL-蛋胺酸0.9克，L-赖胺酸0.5克，复合维生素1.8克，磷酸氢钙1.5g，用玉米粉调制总量至100g。28 grams of soybean powder, 14 grams of fish meal, 6 grams of fructooligosaccharides, 4 grams of isomaltooligosaccharides, 4 grams of bacillus, 5 grams of bifidobacteria, 6 grams of lactic acid bacteria, 6 grams of yeast, 2.8 grams of astragalus, 3.5 grams of Codonopsis, 4.5 grams of soybean lecithin, 0.9 grams of DL-methionine, 0.5 grams of L-lysine, 1.8 grams of multivitamins, 1.5 grams of calcium hydrogen phosphate, prepared with corn flour to 100 grams.
优选的狐免疫增强剂(3)(每100克)含有如下成分：The preferred fox immune enhancer (3) (per 100 grams) contains the following ingredients:
大豆粉22克，鱼粉11克，果寡糖4克，异麦芽寡糖2克，芽孢杆菌2.5克，双歧杆菌3.5克，乳酸菌4克，酵母菌4克，黄芪1.5克，党参2克，大豆卵磷脂3克，DL-蛋胺酸0.6克，L-赖胺酸0.3克，复合维生素1.0克，磷酸氢钙1.2g，用玉米粉调制总量至100g。22 grams of soybean powder, 11 grams of fish meal, 4 grams of fructooligosaccharides, 2 grams of isomaltooligosaccharides, 2.5 grams of bacillus, 3.5 grams of bifidobacteria, 4 grams of lactic acid bacteria, 4 grams of yeast, 1.5 grams of astragalus, 2 grams of codonopsis, 3 grams of soybean lecithin, 0.6 grams of DL-methionine, 0.3 grams of L-lysine, 1.0 grams of multivitamins, 1.2 grams of calcium hydrogen phosphate, prepared with corn flour to 100 grams.
本发明为增强狐机体免疫机能的营养性添加剂，富含高蛋白、氨基酸、矿物质及复合维生素等多种营养素，有助于增强体质健康及免疫机能。一般狐的育成期正处于高温的夏季，肠炎、下痢等消化道疾病经常发生，严重个体出现便血、脱肛等症状，死亡率较高。本发明复合添加果寡糖、异麦芽寡糖、双歧杆菌、乳酸菌、酵母菌、黄芪、党参、复合维生素及多种矿物质，能有效抑制蓝狐、银狐肠道内有害菌的生长，增加有益菌的数量，调理肠道微生态平衡，有效预防和治疗蓝狐、银狐肠炎、下痢等消化道疾病，增强机体免疫力。同时促进蓝狐、银狐肠道内源性消化酶的分泌，提高氨基酸、糖类、脂肪酸及各种矿物质的吸收利用率，提高生产性能。The invention is a nutritional additive for enhancing the immune function of a fox body, which is rich in various nutrients such as high protein, amino acid, minerals and compound vitamins, and helps to enhance physical health and immune function. Generally, the breeding period of foxes is in the hot summer, and digestive tract diseases such as enteritis and diarrhea often occur. In severe cases, symptoms such as blood in the stool and prolapse of the anus occur, and the mortality rate is relatively high. The present invention adds fructooligosaccharides, isomaltooligosaccharides, bifidobacterium, lactic acid bacteria, yeast, astragalus, Codonopsis pilosula, compound vitamins and various minerals, which can effectively inhibit the growth of harmful bacteria in the intestines of blue foxes and silver foxes, increase The number of beneficial bacteria can regulate the balance of intestinal microecology, effectively prevent and treat blue fox, silver fox enteritis, diarrhea and other digestive tract diseases, and enhance the body's immunity. At the same time, it promotes the secretion of endogenous digestive enzymes in the intestines of blue foxes and silver foxes, improves the absorption and utilization of amino acids, sugars, fatty acids and various minerals, and improves production performance.
本发明的狐免疫增强剂具有如下优点：Fox immune enhancer of the present invention has the following advantages:
1、本发明以优质大豆粉及优质鱼粉作为载体，复合添加果寡糖、异麦芽寡糖等益生元成分及光合细菌、酵母菌、乳酸菌、双歧杆菌等有益菌，将优势菌群作为微生态制剂进行补充，通过竞争性抑制、产生抗菌物质和营养物质竞争等途径，直接抑制病原微生物在狐胃肠道粘膜上的粘附和定植，就可以恢复正常菌群的数量、种类和比例的平衡，从而达到抑制病原菌的生长和繁殖的目的。1. The present invention uses high-quality soybean powder and high-quality fish meal as carriers, and adds prebiotic components such as fructooligosaccharides and isomaltooligosaccharides, and beneficial bacteria such as photosynthetic bacteria, yeast, lactic acid bacteria, and bifidobacteria, and uses the dominant flora as microbes. Supplementing with ecological preparations can directly inhibit the adhesion and colonization of pathogenic microorganisms on the mucous membrane of the gastrointestinal tract of foxes through competitive inhibition, production of antibacterial substances, and competition of nutrients, so as to restore the normal flora quantity, type and proportion. Balance, so as to achieve the purpose of inhibiting the growth and reproduction of pathogenic bacteria.
2、芽孢杆菌类以某种免疫调节因子的形式刺激宠物犬肠道产生粘膜抗体，提高机体抵抗病原菌的能力；双歧杆菌能刺激狐机体产生干扰素，提高免疫球蛋白浓度，增强巨噬细胞的活性，表现出明显的非特异性免疫作用；乳酸菌制剂可以促进狐机体中枢免疫器官的发育，可以刺激幼狐自身免疫系统的提早建立，从而增强对疾病的抵抗力。2. Bacillus stimulates the intestinal tract of pet dogs to produce mucosal antibodies in the form of certain immune regulatory factors, improving the body’s ability to resist pathogenic bacteria; Bifidobacteria can stimulate the body of foxes to produce interferon, increase the concentration of immunoglobulins, and strengthen macrophages. lactic acid bacteria preparation can promote the development of the central immune organs of the fox body, and can stimulate the early establishment of the young fox's own immune system, thereby enhancing the resistance to diseases.
3、本发明能有效促进蓝狐、银狐肠道内源性消化酶的分泌，改善狐的消化吸收功能。合成多种氨基酸，产生乳酸，改善新陈代谢系统，提高氨基酸、糖类、脂肪酸及各种矿物质的吸收利用率，提高生产性能。3. The present invention can effectively promote the secretion of endogenous digestive enzymes in the intestines of blue foxes and silver foxes, and improve the digestion and absorption functions of foxes. Synthesize a variety of amino acids, produce lactic acid, improve the metabolic system, increase the absorption and utilization of amino acids, sugars, fatty acids and various minerals, and improve production performance.
4、本发明复合添加黄芪、党参等中草药，能有效抑制蓝狐、银狐肠道内大肠杆菌及沙门氏菌等有害菌数量的增加，预防腹泻及下痢，增强蓝狐、银狐抗病力。在高温的夏季，本产品可用于治疗育成期的蓝狐、银狐幼子及亚成体肠炎、下痢等消化道疾病，有效治疗便血、脱肛等症状，减少死亡率。4. The compound addition of Astragalus, Codonopsis and other Chinese herbal medicines in the present invention can effectively inhibit the increase of harmful bacteria such as Escherichia coli and Salmonella in the intestines of blue foxes and silver foxes, prevent diarrhea and diarrhea, and enhance the disease resistance of blue foxes and silver foxes. In hot summer, this product can be used to treat gastrointestinal diseases such as enteritis and diarrhea in young blue foxes and silver foxes and subadults in the breeding period, effectively treat symptoms such as blood in the stool and prolapse of the anus, and reduce mortality.
5、本发明的产品取材容易，成本价格低廉，易于推广。5. The product of the present invention is easy to obtain materials, has low cost and low price, and is easy to popularize.
具体实施方式Detailed ways
以下通过具体的实施例对本发明的技术方案作进一步描述。以下实施例的作用应被理解为是对本发明的诠释而非对本发明的任何方式的限制。The technical solution of the present invention will be further described below through specific examples. The functions of the following examples should be understood as interpretation of the present invention rather than limitation of the present invention in any way.
实施例1Example 1
本发明的营养性狐免疫增强剂可按本领域的常规方法配制，即分别称取大豆粉25克、鱼粉12克、果寡糖5克、异麦芽寡糖3克、芽孢杆菌3克、双歧杆菌4克、乳酸菌5克、酵母菌5克、黄芪2克、党参3克、大豆卵磷脂4克、DL-蛋胺酸0.8克、L-赖胺酸0.4克、复合维生素1.5克、磷酸氢钙1.2g，用玉米粉调制总量至100g，混合均匀。其中所用的大豆粉及玉米粉均为采用饲料领域或食品领域的加工方法制成的熟粉，所有制备过程均在无菌条件下进行。该配方用于蓝狐、银狐养殖时，能促进肠道内有益菌的生长、抑制有害菌的大量繁殖，调节肠道微生态平衡，提高肠道对蛋白质、脂肪、糖类等营养成分的消化吸收及利用，有效增加蓝狐、银狐免疫机能及生产性能，提高人工养殖的经济效益。The nutritional fox immune enhancer of the present invention can be formulated according to conventional methods in the art, that is, 25 grams of soybean meal, 12 grams of fish meal, 5 grams of fructooligosaccharide, 3 grams of isomaltooligosaccharide, 3 grams of bacillus, bismuth 4 grams of Mycobacterium, 5 grams of lactic acid bacteria, 5 grams of yeast, 2 grams of astragalus, 3 grams of Codonopsis pilosula, 4 grams of soybean lecithin, 0.8 grams of DL-methionine, 0.4 grams of L-lysine, 1.5 grams of multivitamins, phosphoric acid Calcium hydrogen 1.2g, adjust the total amount to 100g with corn flour, mix well. The soybean flour and corn flour used are cooked flour made by the processing method in the feed field or the food field, and all the preparation processes are carried out under aseptic conditions. When this formula is used in breeding blue foxes and silver foxes, it can promote the growth of beneficial bacteria in the intestines, inhibit the proliferation of harmful bacteria, regulate the balance of intestinal microecology, and improve the digestion of nutrients such as protein, fat, and sugar in the intestines Absorption and utilization can effectively increase the immune function and production performance of blue foxes and silver foxes, and improve the economic benefits of artificial breeding.
本产品可采用袋装或者罐装的方式包装，重量在50Kg内，适宜低温干燥条件下保存。在蓝狐、银狐育成期(断乳开始至4月龄幼狐)2～3天饲喂一次，长毛期(4月龄至成体)3～4天饲喂一次，每次用量5～10克，与颗粒状日粮混合或单独饲喂均可，相混合的日粮温度不能高于40℃。用于治疗肠炎、下痢等肠道疾病个体时，每天饲喂1～2次，每次用量10g左右。本产品亦可与狐饲料配合使用，使用剂量为0.05～0.1％。使用本产品饲喂一个月后，对育成期蓝狐、银狐血液中免疫细胞含量及粪便中大肠杆菌、沙门氏菌等有害菌含量进行测定，结果表明：血液中免疫细胞含量显著增加，而粪便中大肠杆菌、沙门氏菌等有害菌数量显著降低。This product can be packaged in bags or cans, with a weight of less than 50Kg, and is suitable for storage at low temperature and dry conditions. During the breeding period of blue fox and silver fox (from the beginning of weaning to 4-month-old young fox), feed once every 2-3 days, and feed once every 3-4 days during the long-haired period (from 4-month-old to adult), with a dosage of 5-5 10 grams, can be mixed with granular rations or fed alone, and the temperature of the mixed rations should not be higher than 40°C. When it is used to treat individuals with intestinal diseases such as enteritis and diarrhea, it is fed 1-2 times a day, and the dosage is about 10g each time. This product can also be used in conjunction with fox feed, and the dosage is 0.05-0.1%. After feeding with this product for one month, the content of immune cells in the blood of blue foxes and silver foxes in the breeding period and the content of harmful bacteria such as Escherichia coli and Salmonella in feces were measured. The number of harmful bacteria such as E. coli and Salmonella is significantly reduced.
实施例2Example 2
分别称取大豆粉28克、鱼粉14克、果寡糖6克、异麦芽寡糖4克、芽孢杆菌4克、双歧杆菌5克、乳酸菌6克、酵母菌6克、黄芪2.8克、党参3.5克、大豆卵磷脂4.5克、DL-蛋胺酸0.9克、L-赖胺酸0.5克、复合维生素1.8克、磷酸氢钙1.5g，用玉米粉调制总量至100g，混合均匀。其中所用的大豆粉及玉米粉均为采用饲料领域或食品领域的加工方法制成的熟粉，所有制备过程均在无菌条件下进行。该配方可与蛋黄、奶粉或饲料配合使用，改善肠道吸收、帮助消化，既为幼狐离乳时的最佳营养剂，亦能治疗育成期的蓝狐、银狐幼子及亚成体肠炎、下痢等消化道疾病，有效治疗便血、脱肛等症状，减少死亡率。Weigh 28 grams of soybean powder, 14 grams of fish meal, 6 grams of fructooligosaccharide, 4 grams of isomaltooligosaccharide, 4 grams of bacillus, 5 grams of bifidobacterium, 6 grams of lactic acid bacteria, 6 grams of yeast, 2.8 grams of astragalus, Codonopsis pilosula 3.5 grams, 4.5 grams of soybean lecithin, 0.9 grams of DL-methionine, 0.5 grams of L-lysine, 1.8 grams of multivitamins, 1.5 grams of calcium hydrogen phosphate, the total amount is prepared with corn flour to 100 grams, and mixed evenly. The soybean flour and corn flour used are cooked flour made by the processing method in the feed field or the food field, and all the preparation processes are carried out under aseptic conditions. This formula can be used in conjunction with egg yolk, milk powder or feed to improve intestinal absorption and help digestion. It is not only the best nutrient for young fox weaning, but also can treat blue fox, silver fox cubs and subadult enteritis, Diarrhea and other gastrointestinal diseases, effective treatment of blood in the stool, rectal prolapse and other symptoms, reduce mortality.
本产品可采用袋装或者罐装的方式包装，重量在50Kg内，适宜低温干燥条件下保存。在蓝狐、银狐育成期(断乳开始至4月龄幼狐)2～3天饲喂一次，长毛期(4月龄至成体)3～4天饲喂一次，每次用量5～8克，与颗粒状日粮混合或单独饲喂均可，相混合的日粮温度不能高于40℃。本产品亦可与狐饲料配合使用，使用剂量为0.05～0.1％。使用本产品饲喂一个月后，有效抑制蓝狐、银狐肠道内大肠杆菌及沙门氏菌等有害菌数量，预防腹泻及下痢，增强蓝狐、银狐抗病力。This product can be packaged in bags or cans, with a weight of less than 50Kg, and is suitable for storage at low temperature and dry conditions. During the breeding period of blue fox and silver fox (from the beginning of weaning to 4-month-old young fox), feed once every 2-3 days, and feed once every 3-4 days during the long-haired period (from 4-month-old to adult), with a dosage of 5-5 8 grams, can be mixed with granular rations or fed alone, and the temperature of the mixed rations should not be higher than 40°C. This product can also be used in conjunction with fox feed, and the dosage is 0.05-0.1%. After feeding with this product for one month, it can effectively inhibit the number of harmful bacteria such as Escherichia coli and Salmonella in the intestines of blue foxes and silver foxes, prevent diarrhea and diarrhea, and enhance the disease resistance of blue foxes and silver foxes.
实施例3Example 3
分别称取大豆粉22克、鱼粉11克、果寡糖4克、异麦芽寡糖2克、芽孢杆菌2.5克、双歧杆菌3.5克、乳酸菌4克、酵母菌4克、黄芪1.5克、党参2克、大豆卵磷脂3克、DL-蛋胺酸0.6克、L-赖胺酸0.3克、复合维生素1.0克、磷酸氢钙1.2g，用玉米粉调制总量至100g，混合均匀。其中所用的大豆粉及玉米粉均为采用饲料领域或食品领域的加工方法制成的熟粉，所有制备过程均在无菌条件下进行。该配方能有效促进蓝狐、银狐肠道内源性消化酶的分泌，改善狐的消化吸收功能，亦可合成多种氨基酸，产生乳酸，改善新陈代谢系统，提高氨基酸、糖类、脂肪酸及各种矿物质的吸收利用率，提高生产性能。Weigh 22 grams of soybean powder, 11 grams of fish meal, 4 grams of fructooligosaccharide, 2 grams of isomaltooligosaccharide, 2.5 grams of bacillus, 3.5 grams of bifidobacterium, 4 grams of lactic acid bacteria, 4 grams of yeast, 1.5 grams of astragalus, Codonopsis pilosula 2 grams, 3 grams of soybean lecithin, 0.6 grams of DL-methionine, 0.3 grams of L-lysine, 1.0 grams of multivitamins, 1.2 grams of calcium hydrogen phosphate, the total amount is adjusted to 100 grams with corn flour, and mixed evenly. The soybean flour and corn flour used are cooked flour made by the processing method in the feed field or the food field, and all the preparation processes are carried out under aseptic conditions. This formula can effectively promote the secretion of endogenous digestive enzymes in the intestines of blue foxes and silver foxes, improve the digestive and absorption functions of foxes, and can also synthesize a variety of amino acids, produce lactic acid, improve the metabolic system, and increase the levels of amino acids, sugars, fatty acids and various Absorption and utilization of minerals, improve production performance.
本产品可采用袋装或者罐装的方式包装，重量在50Kg内，适宜低温干燥条件下保存。在蓝狐、银狐育成期(断乳开始至4月龄幼狐)2～3天饲喂一次，长毛期(4月龄至成体)3～4天饲喂一次，每次用量6～10克，与颗粒状日粮混合或单独饲喂均可，相混合的日粮温度不能高于40℃。本产品亦可与狐饲料配合使用，使用剂量为0.05～0.1％。使用本产品饲喂一个月后，对育成期的蓝狐、银狐日粮中蛋白质、脂肪、糖类及钙、磷矿物质成分的消化率进行测定，结果表明上述营养成分的表观消化率均有所增加，日增重显著提高。This product can be packaged in bags or cans, with a weight of less than 50Kg, and is suitable for storage at low temperature and dry conditions. During the breeding period of blue fox and silver fox (from the beginning of weaning to 4-month-old young fox), feed once every 2-3 days, and feed once every 3-4 days during the long-haired period (from 4-month-old to adult), with a dosage of 6-6 10 grams, can be mixed with granular rations or fed alone, and the temperature of the mixed rations should not be higher than 40°C. This product can also be used in conjunction with fox feed, and the dosage is 0.05-0.1%. After feeding with this product for one month, the digestibility of protein, fat, sugar, calcium and phosphorus mineral components in the rations of blue foxes and silver foxes in the breeding period was measured, and the results showed that the apparent digestibility of the above nutrients Both increased, and the daily weight gain increased significantly.
实施例4Example 4
分别称取大豆粉27克、优质鱼粉13克、果寡糖5.5克、异麦芽寡糖4.5克、芽孢杆菌3.8克、双歧杆菌5.2克、乳酸菌6克、酵母菌4.5克、黄芪2.8克、党参3.2克、大豆卵磷脂6克、DL-蛋胺酸1.0克、L-赖胺酸0.5克、复合维生素1.3克、磷酸氢钙1.4g，用玉米粉调制总量至100g，混合均匀。其中所用的大豆粉及玉米粉均为采用饲料领域或食品领域的加工方法制成的熟粉，所有制备过程均在无菌条件下进行。该配方能显著提高蓝狐、银狐肠道抗病能力，有效预防和治疗蓝狐、银狐肠炎、下痢等消化道疾病，增强机体免疫力。同时促进蓝狐、银狐肠道内源性消化酶的分泌，提高氨基酸、糖类、脂肪酸及各种矿物质的吸收利用率，提高生产性能。Weigh 27 grams of soybean powder, 13 grams of high-quality fish meal, 5.5 grams of fructooligosaccharide, 4.5 grams of isomaltooligosaccharide, 3.8 grams of bacillus, 5.2 grams of bifidobacterium, 6 grams of lactic acid bacteria, 4.5 grams of yeast, 2.8 grams of astragalus, Codonopsis 3.2g, soybean lecithin 6g, DL-methionine 1.0g, L-lysine 0.5g, multivitamin 1.3g, calcium hydrogen phosphate 1.4g, the total amount is prepared with corn flour to 100g, and mixed evenly. The soybean flour and corn flour used are cooked flour made by the processing method in the feed field or the food field, and all the preparation processes are carried out under aseptic conditions. The formula can significantly improve the intestinal disease resistance of blue foxes and silver foxes, effectively prevent and treat digestive tract diseases such as enteritis and diarrhea in blue foxes and silver foxes, and enhance the body's immunity. At the same time, it promotes the secretion of endogenous digestive enzymes in the intestines of blue foxes and silver foxes, improves the absorption and utilization of amino acids, sugars, fatty acids and various minerals, and improves production performance.
本产品可采用袋装或者罐装的方式包装，重量在50Kg内，适宜低温干燥条件下保存。在蓝狐、银狐育成期(断乳开始至4月龄幼狐)2～3天饲喂一次，长毛期(4月龄至成体)3～4天饲喂一次，每次用量5～10克，与颗粒状日粮混合或单独饲喂均可，相混合的日粮温度不能高于40℃。本产品亦可与狐饲料配合使用，使用剂量为0.05～0.1％。使用本产品饲喂一个月后，促进蓝狐、银狐肠道内有益菌的生长、抑制有害菌的大量繁殖，调节肠道微生态平衡，提高肠道对蛋白质、脂肪、糖类等营养成分的消化吸收及利用，有效增加蓝狐、银狐免疫机能及生产性能，提高人工养殖的经济效益。This product can be packaged in bags or cans, with a weight of less than 50Kg, and is suitable for storage at low temperature and dry conditions. During the breeding period of blue fox and silver fox (from the beginning of weaning to 4-month-old young fox), feed once every 2-3 days, and feed once every 3-4 days during the long-haired period (from 4-month-old to adult), with a dosage of 5-5 10 grams, can be mixed with granular rations or fed alone, and the temperature of the mixed rations should not be higher than 40°C. This product can also be used in conjunction with fox feed, and the dosage is 0.05-0.1%. After feeding with this product for one month, it can promote the growth of beneficial bacteria in the intestinal tract of blue foxes and silver foxes, inhibit the proliferation of harmful bacteria, regulate the intestinal micro-ecological balance, and improve the intestinal absorption of protein, fat, sugar and other nutrients. Digestion, absorption and utilization can effectively increase the immune function and production performance of blue foxes and silver foxes, and improve the economic benefits of artificial breeding.
Claims (4)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006101192574A CN100563671C (en) | 2006-12-07 | 2006-12-07 | Fox immune booster |
Applications Claiming Priority (1)
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| CNB2006101192574A CN100563671C (en) | 2006-12-07 | 2006-12-07 | Fox immune booster |
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| CN1969941A true CN1969941A (en) | 2007-05-30 |
| CN100563671C CN100563671C (en) | 2009-12-02 |
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| CNB2006101192574A Expired - Fee Related CN100563671C (en) | 2006-12-07 | 2006-12-07 | Fox immune booster |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101204541B (en) * | 2007-12-13 | 2010-04-14 | 上海交通大学 | Male fox and raccoon reproductive function enhancer |
| CN101347183B (en) * | 2008-09-22 | 2011-01-19 | 北京市爱德利都饲料科技开发有限公司 | Compound additive agent for fox, raccoon dog and mink |
| CN101965901A (en) * | 2010-09-28 | 2011-02-09 | 张海员 | Feed microbial mixture and preparation method thereof |
| CN102613419A (en) * | 2012-04-17 | 2012-08-01 | 唐山师范学院 | Preparation method for nutritional solution for improving growth of fur-bearing animals and application thereof |
| US20130089641A1 (en) * | 2011-10-11 | 2013-04-11 | Sunway Biotech Co., Ltd. | Soymilk with Additive of Vitamin C, Vitamin C salt or Vitamin C Stereoisomer |
| CN103250903A (en) * | 2013-05-20 | 2013-08-21 | 大连理工大学 | Efficacy nutritive cream for fur-bearing animal and preparation method thereof |
| CN103283994A (en) * | 2013-05-14 | 2013-09-11 | 王慧军 | All-expanded pellet feed for foxes, and preparation method thereof |
| CN103330059A (en) * | 2013-06-21 | 2013-10-02 | 四川恒通动物制药有限公司 | Health care composition for livestock as well as preparation method and application thereof |
| CN103583870A (en) * | 2013-10-17 | 2014-02-19 | 蚌埠市丰牧牛羊肉制品有限责任公司 | Feed for improving quality of blue box fur and preparation method thereof |
| CN104522409A (en) * | 2014-12-30 | 2015-04-22 | 青岛七好营养科技有限公司 | Feeding partner for mink pellet feed and preparation method of feeding partner |
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- 2006-12-07 CN CNB2006101192574A patent/CN100563671C/en not_active Expired - Fee Related
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101204541B (en) * | 2007-12-13 | 2010-04-14 | 上海交通大学 | Male fox and raccoon reproductive function enhancer |
| CN101347183B (en) * | 2008-09-22 | 2011-01-19 | 北京市爱德利都饲料科技开发有限公司 | Compound additive agent for fox, raccoon dog and mink |
| CN101965901A (en) * | 2010-09-28 | 2011-02-09 | 张海员 | Feed microbial mixture and preparation method thereof |
| US20130089641A1 (en) * | 2011-10-11 | 2013-04-11 | Sunway Biotech Co., Ltd. | Soymilk with Additive of Vitamin C, Vitamin C salt or Vitamin C Stereoisomer |
| CN102613419A (en) * | 2012-04-17 | 2012-08-01 | 唐山师范学院 | Preparation method for nutritional solution for improving growth of fur-bearing animals and application thereof |
| CN103283994A (en) * | 2013-05-14 | 2013-09-11 | 王慧军 | All-expanded pellet feed for foxes, and preparation method thereof |
| CN103250903A (en) * | 2013-05-20 | 2013-08-21 | 大连理工大学 | Efficacy nutritive cream for fur-bearing animal and preparation method thereof |
| CN103250903B (en) * | 2013-05-20 | 2015-03-11 | 大连理工大学 | Efficacy nutritive cream for fur-bearing animal and preparation method thereof |
| CN103330059A (en) * | 2013-06-21 | 2013-10-02 | 四川恒通动物制药有限公司 | Health care composition for livestock as well as preparation method and application thereof |
| CN103330059B (en) * | 2013-06-21 | 2014-09-17 | 四川恒通动物制药有限公司 | Health care composition for livestock as well as preparation method and application thereof |
| CN103583870A (en) * | 2013-10-17 | 2014-02-19 | 蚌埠市丰牧牛羊肉制品有限责任公司 | Feed for improving quality of blue box fur and preparation method thereof |
| CN103583870B (en) * | 2013-10-17 | 2016-03-02 | 蚌埠市丰牧牛羊肉制品有限责任公司 | A kind ofly improve feed of blue box fur quality and preparation method thereof |
| CN104522409A (en) * | 2014-12-30 | 2015-04-22 | 青岛七好营养科技有限公司 | Feeding partner for mink pellet feed and preparation method of feeding partner |
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| CN100563671C (en) | 2009-12-02 |
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