CN1736221B - A kind of milk powder for reducing or maintaining body weight and its preparation method - Google Patents
A kind of milk powder for reducing or maintaining body weight and its preparation method Download PDFInfo
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- CN1736221B CN1736221B CN 200410058385 CN200410058385A CN1736221B CN 1736221 B CN1736221 B CN 1736221B CN 200410058385 CN200410058385 CN 200410058385 CN 200410058385 A CN200410058385 A CN 200410058385A CN 1736221 B CN1736221 B CN 1736221B
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Abstract
本发明优选了肉碱、维生素、矿物质等8种物质，与脱脂奶粉制备出降低或保持体重的奶粉。本发明的脱脂奶粉还可以通过液体奶喷雾干燥制备。服用本发明的奶粉后，服用者血压无改变作用，血液系统、尿、便常规检验也未见异常，配方成分对肝肾功能无任何损害作用。服用配方成分的受试者体重和腰围均有明显减小。受试者臀围也有减小趋势别。试食组人群血清瘦素和胰岛素水平均较实验前下降。The present invention preferably selects 8 kinds of substances such as carnitine, vitamins and minerals, and prepares milk powder for reducing or maintaining body weight with skimmed milk powder. The skim milk powder of the present invention can also be prepared by spray-drying liquid milk. After taking the milk powder of the present invention, the blood pressure of the taker does not change, and the blood system, urine, and stool routine examinations have no abnormality, and the formula components have no damage to the liver and kidney functions. Subjects taking the ingredients in the formula experienced significant reductions in body weight and waist circumference. There was also a tendency for the hip circumference of the subjects to decrease. The levels of serum leptin and insulin in the trial group were lower than those before the experiment.
Description
Technical field
The present invention relates to a kind of reduction or keep milk powder of body weight and preparation method thereof, comprise mineral matter and vitamin in this milk powder.
Background technology
Contain a large amount of carbohydrate, fat, protein in the milk powder; it is outstanding composite nutrient food; but too much use usually can be causeed fat; but do not occur as yet at present supplying nutritional support; the milk powder that can not cause body weight to increase again; cause many overweight peoples to be unwilling to eat milk powder, in the course of time, cause their nutrient imbalance again.
Modern study shows that obesity is to cause chronic Nutrition and Metabolism imbalance because chronic energy is taken in greater than energy consumption, and the epidemiological study data shows that mineral matter, vitamin content are lower than normal population in overweight people's body.Zoopery has confirmed that fat mouse is suitably replenished mineral matter, vitamin can obviously improve metabolic disorder.
The energy that the overweight people took in can not be caused the disorder of carbohydrate, fat, energy and hormone metabolism by effective metabolism, thereby secondary and fat relevant diabetes, hypertension, hyperlipidemia and cancer is occurred frequently.Therefore obesity has caused the concern of many countries to the harm of human health.China's recent two decades comes, and the incidence of obesity and relevant disease thereof also is ascendant trend year by year, has accounted for dead first as angiocardiopathy.Therefore fat one of the nutritive disease that attracts most attention in the world wide that become.
Obviously, only contain nutrients such as a large amount of carbohydrate, fat, protein in the milk powder of producing at present, can only be used for nutritional support, and can not guarantee effective absorption metabolism of nutrition, and cause the overweight people to be unwilling to eat milk powder.
Therefore, under the situation of taking in certain energy, keep the poised state of various metabolism, also should correspondingly increase supply essential minerals and vitamin in order to guarantee the overweight people.The purpose of this invention is to provide a kind of composition that is used to prepare the milk powder of regulating obesity, contain specific minerals and vitamins in the said composition, thus the supply of assurance overweight people's carbohydrate, fat, energy minerals and vitamins.Angle from the Nutrition and Metabolism regulation and control makes the overweight people under the prerequisite of nutrient balance, and body weight descends, and blood fat reduces, and obtains good quality of life.
Mineral matter is not only the constituent of body, also is essential keeping aspect the physiological functions such as matter and energy metabolism.Mineral matter absorption in vivo and metabolism exist collaborative or antagonism each other, and they can not synthesize in vivo, take in the interior mineral matter of body through body metabolism, and every day, there be a certain amount of excreting in portion, and therefore must absorb from meals.Vitamin is the class trace low-molecular-weight organic compound of keeping the body vital movement, it promptly is not the primary raw material that constitutes various tissues on physiology, energy source in neither body, but it is in the reaction that energy produces and play crucial effect in the body substance metabolism process.
Vitamin is to keep the necessary class trace of special metabolic response low-molecular-weight organic compound in body normal physiological function and the cell.Between the various vitamins and with other nutrient between the maintenance balance be very important.B1thiaminpyrophosphate ester (TPP) is a Cobastab
1Main coenzyme form, it participates in two important reactions in vivo, be the oxidative deamination reaction and the reaction of pentose phosphate pathway transketolase of 2-ketoacid. the former is the key link that occurs in biological oxidation process in the mitochondria, and the pyruvic acid and the KG of deriving out from glucose, aliphatic acid, branched-chain amino acid just can enter the citrate cycle exhaustive oxidation through oxidative deamination generation acetyl-CoA and succinyl CoA; The latter is mainly undertaken by transketolase in cytoplasm, though it is not the important channel of glucose oxidase energy supply, but nucleic acid synthesizes required pentose really, fat and roughly the same liquor-saturated important source of synthesizing required NADPH. because acetyl-CoA and succinyl CoA are the key links of three major nutrient metabolism, be again their anabolic tie-points simultaneously. Cobastab
2With the form of FMN and FAD coenzyme as multiple flavo-enzyme, urge in vivo general oxidation reduction reaction one by one.Except performance important role in the respiratory chain energy produces, also amino acid and fat oxidation, protein and some hormone synthesize and the transport process of iron in play a significant role.The basic physiological effect of vitamin D is to keep the inside and outside calcium ion concentration of cell, regulates alcium and phosphor metabolization, regulates the balance of blood calcium by the vitamin D internal system.Vitamin A has the growth of keeping normal vision and epithelium and the normal immunologic function of differentiation and body, and wherein retinoic acid has the effect that the body normal growth is grown of keeping.The L-carnitine is body metabolism necessity " biostearin ", and its major function is to promote lipid metabolism.The L-carnitine is many-sided to the influence of lipid metabolism, can promote oxidation of fatty acids, and the utilization of triglycerides is increased, and can regulate cholesterol generation and distribution in vivo again.It can also influence the composition and the content of lipoprotein simultaneously, shows in zoopery and clinical practice, and treatment hyperlipidemia and the rising of dialysis patient blood fat are had better curative effect.The energy supply that improves some special populations and baby, total parenteral nutrition and congenital lipidosis patient there is important practical usage.Replenish the L-carnitine and can alleviate tool because of lacking the fat metabolic disturbance that causes in the body, the dysfunction of tissue such as skeletal muscle and cardiac muscle.
Calcium is the abundantest inorganic elements of content in the human body.Zemel etc. studies show that, expression and activity that dietary calcium can reduce intracellular calcium concentration and suppress aP2-agouti transgenic mice fatty acid synthetase by suppressing thyroid hormone and 1,25 dihydroxy vitamin D increase steatolysis, and fat is synthetic to be reduced.Skeletal muscle is that tranquillization can show the major decision factor that consumes, and also is the adaptability heat production organ of body maximum.The consumption of proton gradient can promote 50% of resting metabolic rate in the skeletal muscle.Studies show that the high calcium meals can make the expression of UCPS 3mRNA in the skeletal muscle increase, skeletal muscle heat production power consumption is increased, thereby reduce the fat content of body.There are some researches show that also high fat high calcium meals can promote the expression of body leptin and the secretion of free T3, promote the expression of the uncoupling protein gene of skeletal muscle indirectly, thereby promote energy to discharge with the form of heat energy.CALCIUM PYRUVIC is to show one's talent in the motion field at first, subsequently a kind of novel dietary supplements of the fashionable whole society again.CALCIUM PYRUVIC is the compound of pyruvic acid and mineral calcium, and pyruvic acid is natural to be present in vegetables and the fruit, also is one of most important intermediate product in the body metabolism.CALCIUM PYRUVIC is as dietary supplements, has to quicken fat consumption, lose weight, strengthen human tolerance, improve the sports achievement, engulf free radical and suppress the remarkable results such as generation of free radical.
Trivalent chromium is the trace element of needed by human, and its main effect is the intensive as insulin, participates in the metabolism of body glycolipid.It can promote the utilization of cell to glucose, promotes the oxidative phosphorylation of glucose and synthesizing of glycogen, improves the stability of insulin, thereby reduces blood sugar.The shortage of chromium can cause the symptom of similar diabetes.It is relevant with the raising of blood sugar, cholesterol and triglyceride levels that animal used as test is lacked chromium nursing discovery.Palansky etc. studies show that: diabetes rat is replenished chromium can make the blood sugar level of rising reduce 14%-29%, cholesterol reduces by 35%, and triglycerides reduces by 45%.The 1980s, people successfully isolate the interior biologically active form of body-low-molecular-weight chromium bond (LMWCr) of chromium, it combines amino acid (cysteine, glycine, glutamic acid and aspartic acid) and 4 chromium ions of 4 types, the GTF of generally acknowledging before this structure is different from.The mechanism of action of low-molecular-weight chromium bond is: it is present in the cytosol and karyon of insulin sensitivity with the form of precursor.Blood sugar raises and to cause the release of insulin, in insulin and its receptors bind, causes the mobile of chromium ion, and the precursor of low-molecular-weight chromium bond becomes activity form in conjunction with chromium ion, and the receptors bind of it and insulin is kept and amplified insulin signaling.Insulin is to regulate carbohydrate and lipometabolic important hormone, and it mainly acts on is promote the interior neutral fat of cell synthetic, suppresses the mobilization of fat.Because the overweight people reduces the sensitiveness of insulin, thereby cause that secretion of insulin increases, fat is synthetic to be increased, so the increase of insulin level has aggravated obesity in the blood, causes vicious circle.
Publication number is the patent application of CNH1349795A, discloses a kind of slimming medicine, and this medicine is by gripping the soft capsule that linoleic acid is a Main Ingredients and Appearance altogether and forming two kinds of formulation reprovisions of hard shell capsules of being made up of L-l-cn, chromium picolinate, L-5-hydroxytryptophane etc.
Publication number is the patent application of CN1359292A, discloses the slimming composition of a kind of promotion mammal, contains at least three kinds of nutriments in the carbohydrate source of the cereal that is selected from L-carnitine, chromium, vitamin A and is selected from low-glycemic.
But, do not have a kind of milk powder that contains carnitine, vitamin, mineral matter that reduces or keep body weight that is used to prepare in the prior art.Therefore, characteristics of the present invention just have been preferably carnitine, vitamin, mineral matter, prepare the milk powder that reduces or keep body weight.
Technical scheme
It below is technical scheme of the present invention
| Prescription 1 | Content |
| The L-carnitine | 1～3g |
| Methylpyridine chromium | 624～828μg |
| Biological calcium carbonate | 884～2992mg |
| Cobastab 1 | 0.64～2.95mg |
| Cobastab 2 | 0.32～2.62mg |
| Cobastab 6 | 2.64～5.4mg |
| Vitamin E | 6.72～12.76mg |
| Vitamin C | 160～375mg mg |
| Prescription 2 | Content |
| The L-carnitine | 1g |
| Methylpyridine chromium | 624μg |
| Biological calcium carbonate | 884mg |
| Cobastab 1 | 0.64mg |
| Cobastab 2 | 0.32mg |
| Cobastab 6 | 2.64 |
| Prescription 2 | Content |
| Vitamin E | 6.72 |
| Vitamin C | 160mg |
| Prescription 3 | Content |
| The L-carnitine | 3g |
| Methylpyridine chromium | 828μg |
| Biological calcium carbonate | 2992mg |
| Cobastab 1 | 2.95mg |
| Cobastab 2 | 2.62mg |
| Cobastab 6 | 5.4mg |
| Vitamin E | 12.76mg |
| Vitamin C | 375mg |
| Prescription 4 | Content |
| The L-carnitine | 2g |
| Methylpyridine chromium | 724μg |
| Biological calcium carbonate | 1884mg |
| Cobastab 1 | 1.14m |
| Cobastab 2 | 1.32mg |
| Cobastab 6 | 3.64mg |
| Vitamin E | 10.72mg |
| Vitamin C | 260mg |
With the above-mentioned substance weighing, being supplemented to gross weight with milk powder is that 100g people's recommended amounts is: 50 restrain for each person every day, take at twice.
Wherein there is multiple class in the source of milk powder, can adopt conventional skimmed milk power, for example: new hundred benefit the nation New Zealand NZMP board skimmed milk power that border industry and trade Co., Ltd provides, Australia skimmed milk power and Ukraine's skimmed milk power that good prosperous middle Co., Ltd produces, German skimmed milk power and New Zealand's skimmed milk power that South Sea city dandelion dairy industry Co., Ltd produces, can also adopt liquid milk is the skimmed milk power that raw material is made
Milk powder adopts New Zealand NZMP board skimmed milk power (New Zealand NZMP company, No. 25, Wellington, NZL Te Lisi street), and its main component is as follows: lactose 54.1%, protein 33.4%, mineral matter 7.9%, moisture 3.8%, fat 0.8%.
With the liquid milk is that raw material is made functional milk powder, and its technological process is as follows:
Liquid milk is that the technology of the skimmed milk power of raw material making is:
Raw milk: clean breast: fractionation of fatty: standardization: batching (adding 8 kinds of materials such as L-carnitine): sterilization: high-pressure homogeneous: vacuum concentrates: spray-drying: cooling: sieve: packing: finished product
(1) raw milk: with the free of contamination pure fresh milk of health is raw material.
(2) clean breast: milk clarifier is removed foreign matters such as weeds.
(3) centrifugal: the butterfat centrifuge removes degrease.
(4) standardization:, make its content that dusts each main component of back be controlled at this scope: lactose 53.1～55.1%, protein 32.4～34.4%, mineral matter 7.5～8.3%, moisture 3.0～4.0%, fat 0.6～0.9% with the fresh cow milk standardization
(5) batching: 8 kinds of materials such as load weighted L-carnitine are joined in the liquid milk after the standardization, stir.
(6) sterilization: adopt 83 ℃, 15 seconds high temperatures.
(7) high-pressure homogeneous: the pressure homogeneous that adopts 18～22Mpa.
(8) vacuum concentrates: vacuum 600～700Pa, the content that makes dry in the liquid milk is 35～45%.
(9) spray-drying: EAT is controlled at 140～150 ℃, and leaving air temp is controlled at 75～85) ℃ between.
(10) cooling: adopt air-cooledly, milk powder is chilled to rapidly about 4 ℃.
(11) sieve: sieve and remove impurity and insoluble matter in the dry run.
(12) packing: adopt waterproof, lucifuge, free of contamination packaging material are packed.
Finished product: be stored in the environment of 8～12 ℃ of airtight, dry, temperature.
Specific embodiment 1:
Functional components is directly joined in the NZMP board skimmed milk power, and the concrete operations step is as follows:
(1) weighing: L-carnitine 20g, methylpyridine chromium 0.0073g, biological calcium carbonate 18.84g, Cobastab
10.0114g, Cobastab
20.0132g, Cobastab
60.0364g, vitamin E 0.1072g, vitamin C 2.6g amounts to 41.62g, so weighing milk powder (1000-41.6155)=958.3845g.
(2) adopt the SS15-SVP series-V-type powder mixer of different model that interpolation material and milk powder are evenly mixed.
(3) packing, finished product: the milk powder after will mixing, be loaded in the sealing bag, be stored in the dry environment.
Specific embodiment 2:
The concrete operations step is as follows:
Functional materials weighing: L-carnitine 2000g, methylpyridine chromium 0.73g, biological calcium carbonate 1884g, Cobastab
11.14g, Cobastab
21.32g, Cobastab
63.64g, vitamin E 10.72g, vitamin C 260g amounts to 4161.55g,
With above-mentioned functions material material weighing 49.1g, add standardized liquid milk and be supplemented to 10kg
Calculate principle: in the 10kg liquid milk, its dry matter content is 11%, moisture is that 3% (moisture of the dry matter content of liquid milk and milk powder is different and different because of environmental unit etc. during production in the milk powder, replace and get final product). therefore can get the milk powder amount and be (10kg*11%)/(1-3%)=1.134kg, the total amount that adds functional materials is 1.134kg*4.329%=49.1g
Raw milk: with the free of contamination pure fresh milk of health is raw material.
Clean breast: milk clarifier is removed foreign matters such as weeds.
Centrifugal: the butterfat centrifuge removes degrease.
Standardization:, make its content that dusts each main component of back be controlled at this scope: lactose 53.1%, protein 32.4%, mineral matter 7.5%, moisture 3.0%, fat 0.6% with the fresh cow milk standardization
Batching: 8 kinds of materials such as load weighted L-carnitine are joined in the liquid milk after the standardization, stir.
Sterilization: adopt 83 ℃, 15 seconds high temperatures.
High-pressure homogeneous: the pressure homogeneous that adopts 20Mpa.
Vacuum concentrates: vacuum 650Pa, the content that makes dry in the liquid milk is 40%.
Spray-drying: EAT is controlled at 145 ℃, and leaving air temp is controlled at 78 ℃.
Cooling: adopt air-cooledly, make milk powder be chilled to 4 ℃ rapidly.
Sieve: sieve and remove impurity and insoluble matter in the dry run.
Packing: adopt waterproof, lucifuge, free of contamination packaging material are packed.
Finished product: be stored in the environment of 10 ℃ of airtight, dry, temperature.
The zoopery result:
Ablactation Wistar male rat is adopted in zoopery, is divided into the basal feed group at random by body weight, the high lipid food group.The basal feed prescription is selected for use and is isozygotied into feed, its nutrient containing and the basic demand that can guarantee that the rat normal growth is grown, adjust fat content on this basis and be made into high lipid food, after feeding for 8 weeks, weight gain in the high fat group rat is considered as the rat of lipophilia greater than the rat of base set average weight gain.To there be the rat of lipophilia to be divided into high lipid food group and the high lipid food experimental group that adds vitamin and minerals at random then by body weight.Feed the 17th all backs etherization sacrificed by decapitation animal, leave and take all white adipose tissues of kidney week and testis, the result shows in the meals that replenishing mineral matter and vitamin has the reduction effect that shows special to the body weight and the body fat content of obese rat, and the blood fat of obese rat significantly descends.
Basal feed group (being mass fraction): corn 37%, wheat bran 12%, flour 15%, dregs of beans 32%, vegetable oil 1.7%, stone flour 1%, calcium monohydrogen phosphate 0.8%, salt 0.2%, methionine 0.2%, lysine 0.1%
High lipid food group (being mass fraction): cholesterol 2.5%, cream 30%, cholic acid 1%, methylthiouracil 0.2%, normal diet 66.3% adds suitable quantity of water and mixes thoroughly, repressed one-tenth graininess, oven dry.
High fat experimental group: NZMP board skimmed milk power milk powder 20kg, 2.5 kilograms in cholesterol, cream 30kg, 1 kilogram of cholic acid, 0.2 kilogram of methylthiouracil, 0.4 kilogram of L-carnitine, methylpyridine chromium 144.8mg, biological calcium carbonate 376.8g, Cobastab
10.228g, Cobastab
20.264g, Cobastab
60.728g, vitamin E 2.144g, vitamin C 5.4g, normal diet 45.37kg adds suitable quantity of water and mixes thoroughly, repressed one-tenth graininess, oven dry.
Table 1 obese rat body weight and fat body ratio
By table 1 as seen, body weight did not have significant difference before each organized rat experiment, as time passes, the experimental group body weight increases gradually, during to the experiment end, compare with the high lipid food group, high lipid food group body weight and the body fat content that adds 8 kinds of materials such as L-carnitine significantly reduce (P＜0.05 illustrate that 8 kinds of materials such as additional L-carnitine in the meals can significantly reduce the body weight and the body fat content of obese rat.
Table 2 obese rat blood fat
When finishing by the visible experiment of table 2, compare with the high lipid food group, the high fat group T-CHOL of replenishing vitamins and mineral matter, triglycerides all significantly reduce (P＜0.05) in the meals, illustrate to replenish T-CHOL, the triglycerides that above-mentioned minerals and vitamins can significantly reduce obese rat in the meals.
Table 3 obese rat blood sugar, insulin concentration and insulin sensitivity sex index
By table 3 as seen, when experiment finishes, compare with the high lipid food group, high fat experimental group has reduction trend (P＜0.05), and high lipid food group insulin level is the highest, compares the insulin level of high fat experimental group significantly descend (P＜0.05) with it.High lipid food group insulin sensitivity sex index significantly is lower than other each group, illustrates that the insulin resistance phenomenon has appearred in high fat group.
Crowd's experimental result
One, safety indexes
1. general situation is at whole experimental session, and experimenter's state of mind is all good, and appetite is uninfluenced, diet, and stool and urine there is no abnormal change.Experimenter's blood pressure situation sees Table 4.
Table 4 formula components milk powder is to the influence of blood pressure (mmHg)
Annotate: test group: take formula milk, promptly take the milk powder that adds 8 kinds of materials such as L-carnitine, sooner or later respectively once, each 25 grams, 50 ℃ of left and right sides warm boiled waters.
Control group: do not take formula milk, all the other foods [1] are identical with test group.
His-and-hers watches 4 results carry out statistical procedures, test group is taken to compare before and after the formula components milk powder (following experiment is identical) that New Zealand NZMP board skimmed milk power is a raw material and with control group and is not seen significant difference, illustrates that formula components milk powder does not have the change effect to user's blood pressure under this experimental condition.
2. blood, urine, just conventional detection
The routine blood test index that the experimenter takes before and after the formula components milk powder (35 days) sees Table 5, the result shows, white blood cell count(WBC), red blood cell count(RBC) and content of hemoglobin all in range of normal value, illustrate that formula components milk powder does not have injury to hematological system. urine, just also no abnormality seen of routine inspection.
Table 5 formula components milk powder is to the influence of experimenter's routine blood test
Annotate: test group: take formula milk, promptly take the milk powder that adds 8 kinds of materials such as L-carnitine, sooner or later respectively once, each 25 grams, 50 ℃ of left and right sides warm boiled waters.
Control group: do not take formula milk, all the other foods [1] are identical with test group.
3. liver, virtuous Function detection
Liver, renal function and the relevant blood parameters of the experimenter being taken formula components milk powder front and back detect, and it the results are shown in Table 6.
Table 6 formula components milk powder is to the influence of liver, renal function and related biochemical indicator
Annotate: test group: take formula milk, promptly take the milk powder that adds 8 kinds of materials such as L-carnitine, sooner or later respectively once, each 25 grams, 50 ℃ of left and right sides warm boiled waters.
Control group: do not take formula milk, all the other foods
[1]Identical with test group.
Table 3 is the result show, every biochemical indicator is all in range of normal value, and no significant difference before and after the experiment, illustrates that formula components milk powder does not have any detrimental effect to hepatic and renal function.
4. Chest X-rays, electrocardiogram, the Abdominal B type ultrasonography inspection
Each is organized the experimenter and there is no significant difference at the test before and after look.
5. exercise tolerance test result
Experimental technique is the same.
The experimenter took formula components milk powder after 35 days, and exercise tolerance obviously improves, and the used time of running 300m takes before the formula components milk powder and obviously shortens statistical procedures P＜0.01 on flatbed treadmill.And compare the conspicuousness difference is arranged also, the results are shown in Table 4 with the control group crowd.
Formula components milk powder is to the influence of exercise tolerance in the test of table 7 300m road-work
* with the preceding ratio of experiment, P＜0.05 significant difference.△ tests last ratio with control group, P＜0.05 significant difference.
6. bad reaction is observed
Experimental technique is the same.
The edible formula components milk powder of experimenter is after 35 days, and appetite is normal, does not have stomachache, diarrhoea, dizziness, headache, alopecia, bad reaction such as weak.Prove that further it is safe taking formula components milk powder.
Two, dietary survey result
Respectively the experimenter is carried out three days questioning dietary surveys before and after the test, after application form is collected, by composition table of foods the rough heat energy that carries out of eaten food is converted, it the results are shown in Table 8.
Table 8 experimenter meals heat energy is taken in situation
His-and-hers watches 5 statistical disposition as a result as seen, diet was taken in heat before and after the experimenter tested is not had significant difference.
Annotate: test group: take formula milk, promptly take the milk powder that adds 8 kinds of materials such as L-carnitine, sooner or later respectively once, each 25 grams, 50 ℃ of left and right sides warm boiled waters.
Control group: do not take formula milk, all the other foods are identical with test group.
Three, effect index testing result
1. formula components milk powder is to the influence of body weight, waistline, hip circumference, body mass index and overweight degree
The experimenter took formula components milk powder 35 days, and the situation of change of body weight, waistline, hip circumference sees Table 9 and table 10 respectively.
Table 9 formula components milk powder is to the influence of experimenter's body weight
* with experiment before ratio, P＜0.05, △ and control group are tested the end and are compared P＜0.05
Table 10 formula components milk powder is to the influence of experimenter's waistline, hip circumference
* with before the experiment compare, P＜0.05, △ compares P＜0.05 with control group experiment end
Annotate: test group: take formula milk, promptly take the milk powder that adds 8 kinds of materials such as L-carnitine, sooner or later respectively once, each 25 grams, 50 ℃ of left and right sides warm boiled waters.
Control group: do not take formula milk, all the other foods [1] are identical with test group.
The result of table 9 and table 10 shows, taking experimenter's body weight of formula components milk powder and waistline all has obviously and reduce, and comparing with before the experiment or control group experiment end all has meter to learn meaning.Experimenter's hip circumference also has the trend of reducing, but handles no conspicuousness difference by statistics.
The experimenter took formula components milk powder after 35 days, and the situation of change of body mass index and overweight degree sees Table 8.
Table 11 formula components milk powder is to the influence of experimenter's body weight index and overweight degree
* with before the experiment compare P＜0.05
△ compares P＜0.05 with control group experiment end
Annotate: test group: take formula milk, promptly take the milk powder that adds 8 kinds of materials such as L-carnitine, sooner or later respectively once, each 25 grams, 50 ℃ of left and right sides warm boiled waters.
Control group: do not take formula milk, all the other foods
[1]Identical with test group.
Table 11 is the result show, takes formula components milk powder milk powder experimenter's body weight index is obviously descended, but overweight degree is not had obvious influence (comparing no difference of science of statistics with before the experiment or control group experiment end).
2. to the influence of body fat content
Before and after the experiment 4 of experimenter's healths are measured the site and measure subcutaneous fat thickness, the results are shown in Table 12, these table data show that C, D 2 points (being respectively sour jujube place on other 3cm place of right navel and the right bone courage) subcutaneous fat thickness have significant difference, after being test-meal formula components milk powder milk powder, this two places subcutaneous fat is reduced.
Table 12 formula components milk powder milk powder is to the influence of experimenter's subcutaneous fat thickness
* with before the experiment compare, P＜0.05, △ compares P＜0.05 with control group experiment end
Annotate: test group: take formula milk, promptly take the milk powder that adds 8 kinds of materials such as L-carnitine, sooner or later respectively once, each 25 grams, 50 ℃ of left and right sides warm boiled waters.
Control group: do not take formula milk, all the other foods
[1]Identical with test group.
Four, other index determining result
1. formula components milk powder milk powder is to the influence of Serum Leptin Levels, insulin
The experimenter took formula components milk powder milk powder after 35 days, measured Serum Leptin Levels and insulin, and it the results are shown in Table 13.The data of his-and-hers watches 13 are carried out statistical analysis, the result shows that test-meal group crowd's Serum Leptin Levels and insulin level are all than descend before the experiment (P＜0.05), obviously do not improve and have before and after the control group experiment, more also there were significant differences to test last two groups of Serum Leptin Levels and insulin level.
Table 13 formula components milk powder milk powder is to the influence of Serum Leptin Levels, insulin
* with before the experiment compare, P＜0.05, △ compares P＜0.05 with control group experiment end
Annotate: test group: take formula milk, promptly take the milk powder that adds 8 kinds of materials such as L-carnitine, sooner or later respectively once, each 25 grams, 50 ℃ of left and right sides warm boiled waters.
Control group: do not take formula milk, all the other foods
[1]Identical with test group.
2. formula components milk powder milk powder is to the influence of experimenter's blood fat
To experimenter's lipids detection, the result shows that formula components milk powder milk powder can make serum total cholesterol, triglyceride levels significantly descends, with the experiment before compare, or compare latter stage with the control group experiment significant difference is all arranged, and the HDL-C level is not had obvious change effect, the results are shown in Table 14.
Table 14 formula components milk powder milk powder is to the influence of experimenter's blood fat
Compare before material and the experiment, P＜0.01, P＜0.01 is compared at △ △ and control group experiment end
* with before the experiment compare, P＜0.05, △ compares P＜0.05 with the control group experiment
Annotate: test group: take formula milk, promptly take the milk powder that adds 8 kinds of materials such as L-carnitine, sooner or later respectively once, each 25 grams, 50 ℃ of left and right sides warm boiled waters.
Control group: do not take formula milk, all the other foods
[1]Identical with test group.
With other conventional skimmed milk powers is the function milk powder of raw material preparation, obtains same effect.
After being the function milk powder of raw material preparation with the skimmed milk power that derives from liquid milk, also obtained same effect,
List of references
1. China Light Industry Press is write by " DRIs " Chinese Soclety of Nutrition
2. State Standard of the People's Republic of China GB14880-94 " food enrichment use sanitary standard "
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" 20. Nutrition and Food Hygiene " the 5th edition Wu Kun chief editor
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