CN1785343A - Ready prepared Chinese medicine for treating epicophosis and sonitus - Google Patents
Ready prepared Chinese medicine for treating epicophosis and sonitus Download PDFInfo
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Abstract
A Chinese patent medicine for treating tinnitus and deafness is prepared from 14 Chinese-medicinal materials including wild jujube, yarn, cordyceps, safflower, etc through mixing, baking, decocting three of them twice, mixing with the powder of others, baking, sterilizing and loading in capsules.
Description
One. technical field: the present invention relates to a kind of medicine, particularly relate to the Chinese patent medicine for the treatment of deafness and tinnitus.
Two. background technology: deafness and tinnitus is commonly encountered diseases and frequently-occurring disease, particularly middle-aged and elderly people is more common, analyze according to China's national people with disability's deafness and tinnitus findings of the survey in 1987, show that deafness and tinnitus accounts for 15～20% of China's population, make patient's study, life, work has been subjected to seriously influencing, up to the present, deafness and tinnitus remains a kind of difficult disease, does not still have the specific drug treatment.Doctor trained in Western medicine thinks that it is because multiple harmful factor damage cochlea and acous result, as viral infection, ototoxic drug, noise, nephropathy, hypertension and immunological disease etc., along with the paces quickening of reform and opening-up and the quickening of people's rhythm of life, people's pressure is increasing over particularly past 10 years, and the deafness and tinnitus patient has the trend of increase greatly, be divided into sudden deafness and tinnitus clinically, presbyacusis tinnitus, infectious deafness and tinnitus, damaging deafness and tinnitus, congenital deafness tinnitus, noise deaf tinnitus etc. mainly adopt the means of nutrition auricularis cell, cooperate to adopt hyperbaric oxygentherapy, the intravenous injection antithrombotic, blood circulation promoting medicine etc.
" element ask the writings left behind by the deceased acupuncture manipulation opinion " said: " in healthy energy deposited, heresy can not be done." " element ask comment heat opinion " says: " and heresy gather, its gas must be empty." ear is the function of the kidney, kidney storing essence is given birth to marrow; Irritability is led in ear, blood stored in the liver; Feel concerned about key in ear, heart governing blood and vessels; Spleen is a source of generating QI and blood etc.Therefore, deafness and tinnitus be visceral dysfunctions such as kidney, the heart, spleen, liver, the result of exopathogen such as ailment said due to cold or exposure, damp, pathogenic heat invasion and attack.Deficiency of the kidney, ear are become homeless and are filled, and weakness of the spleen and stomach loses fortune, QI and blood can not on give, ear is become homeless foster; Disturb key clearly on the fire of liver and gall, phlegm-fire is stopped up knot ear key, obstructing airway, the wind heat exopathogen is invaded the gill key, cause the ear key obstructed, or the key that empties hoodwinked, lost the normal function of " can respond to clearly; sky can be received sound ", and causing deafness and tinnitus, the Chinese medicine preparation for the treatment of deafness and tinnitus at present is also few, comprises medicine for external use and oral medicine, medicine for external use such as Nasal Drops are dripped ear, bright Rhizoma Acori Graminei juice drips ear etc., and these medicines have only played the respite effect, can't resolve deafness and tinnitus originally, in the oral medicine, traditional BUZHONG YIQI WAN, Bolus for Clearing Heat and Phlegm, LIUWEI DIHUANG WAN etc., though the part curative effect is arranged, does not have special specific aim for deafness and tinnitus.CN1391948A, 02135305.0 is called a kind of Chinese medicinal granule electuary for the treatment of deafness, tinnitus, it is introduced evident in efficacyly, but the processing technology that its adopts is loaded down with trivial details, and utilization Moschus rare medicinal herbs, production cost is higher, increases patient's financial burden.CN1559594A, 200410025936.6 are called a kind of Chinese medicine for the treatment of deafness and tinnitus, use Scorpio in this invention, and contain scorpion venom in the Scorpio, and its main harm is to make respiratory paralysis.CN1454636A, 03117433.7 name is called a kind of medicine for the treatment of deafness and tinnitus and preparation method thereof, the raw material of this invention is a Fructus Jujubae, Rhizoma Acori Graminei, Fructus Crotonis, and Fructus Crotonis is very toxic, Fructus Crotonis does not deoil in its preparation method, though evaporable Oleum Tiglii can directly stimulate the acupuncture point of ear and acoustic nerve and reach therapeutic purposes, but evaporable Oleum Tiglii also has intense stimulus to the thin tender skin of auditory meatus, easily causes the erosion of auditory meatus to hinder, and the Oleum Tiglii that contains in the Fructus Crotonis, croton resin, crotonyl alcohol. lipid material have weak carcinogenic activity.
Three. summary of the invention:
The objective of the invention is to overcome the defective of prior art, provide a kind of pure Chinese medicinal preparation that has no side effect for the treatment of deafness and tinnitus, and this Chinese patent medicine technology is simple, implement easily, taking convenience, curative effect is good, is applicable to various deafness and tinnitus.
Technical scheme of the present invention: a kind of Chinese patent medicine for the treatment of Hiccough and deaf, containing with the weight portion is the following bulk drugs of unit, 1～6 part of Cornu Saigae Tataricae, 6～20 parts of Semen Ziziphi Spinosaes, 9～30 parts of dried Rhizoma Dioscoreaes, 15～60 parts in Radix Rehmanniae Preparata, 9～30 parts of Fructus Corni, 8～30 parts of Radix Scrophulariae, 3～7 parts of Cordyceps, 5～15 parts of Rhizoma Acori Graminei, 9～20 parts of Magnetitums, 6～15 parts of Rhizoma Alismatis, 5～15 parts on Flos Carthami, 8～30 parts of Endothelium Corneum Gigeriae Galli.
Described Chinese patent medicine, wherein Cornu Saigae Tataricae is 1～4 part, 10～15 parts of Semen Ziziphi Spinosaes, 15～25 parts of dried Rhizoma Dioscoreaes, 25～48 parts in Radix Rehmanniae Preparata, 14～28 parts of Fructus Corni, 10～24 parts of Radix Scrophulariae, 3～6 parts of Cordyceps, 7～12 parts of Rhizoma Acori Graminei, 9～15 parts of Magnetitums, 8～12 parts of Rhizoma Alismatis, 7～13 parts on Flos Carthami, 14～22 parts of Endothelium Corneum Gigeriae Galli.
Described Chinese patent medicine, wherein Cornu Saigae Tataricae is 1～4 part, 10～13 parts of Semen Ziziphi Spinosaes, 18～25 parts of dried Rhizoma Dioscoreaes, 25～40 parts in Radix Rehmanniae Preparata, 18～25 parts of Fructus Corni, 12～15 parts of Radix Scrophulariae, 3～6 parts of Cordyceps, 10～12 parts of Rhizoma Acori Graminei, 12～15 parts of Magnetitums, 8～12 parts of Rhizoma Alismatis, 9～12 parts on Flos Carthami, 16～20 parts of Endothelium Corneum Gigeriae Galli.
Described Chinese patent medicine also contains 3～8 parts of the Radixs Angelicae Dahuricae, 10～25 parts of Radix Bupleuri, 6～10 parts of Herba Saussureae Involueratae, 25～35 parts of Arillus Longans, 28～40 parts of Semen Sesami Nigrums.
Described Chinese patent medicine is with the crude drug Cornu Saigae Tataricae, Semen Ziziphi Spinosae, and dried Rhizoma Dioscoreae, Radix Scrophulariae, Cordyceps, Rhizoma Acori Graminei, Magnetitum, Rhizoma Alismatis, Flos Carthami, Endothelium Corneum Gigeriae Galli is got part by proportioning, mixes oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; With the crude drug Radix Rehmanniae Preparata, Fructus Corni is got a part chopping by proportioning, adds 8～10 times in water, decocts twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, abundant mixing, oven dry, sterilization.
Described Chinese patent medicine is with the crude drug Cornu Saigae Tataricae, Semen Ziziphi Spinosae, and dried Rhizoma Dioscoreae, Radix Scrophulariae, Cordyceps, Rhizoma Acori Graminei, Magnetitum, Rhizoma Alismatis, Flos Carthami, Endothelium Corneum Gigeriae Galli, the Radix Angelicae Dahuricae, Radix Bupleuri, Herba Saussureae Involueratae, Semen Sesami Nigrum is got part by proportioning, mixes oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; With the crude drug Radix Rehmanniae Preparata, Fructus Corni, Arillus Longan is got a part chopping by proportioning, adds 8～10 times in water, decocts twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, abundant mixing, oven dry, sterilization.
Described Chinese Traditional Medicines are powder, or are capsule, or are pill.
Beneficial effect of the present invention:
1. technology of the present invention is simple, implements easily, and is reasonable in design, in its manufacturing process, specified crude drug got part by proportioning, and oven dry is pulverized together, promptly makes former medicine fine powder originally, not high to specification requirement, simple to operate; Because of Arillus Longan, Radix Rehmanniae Preparata, Fructus Corni are visco-elastic materials, are difficult for pulverizing, and the method that takes juice for a long time, the composition of remaining valid are preferably adopted in design.
2. the present invention is a pure Chinese medicinal preparation, does not contain hormone substance, has no side effect, and taking convenience need not decoct, and can carry.
3. the present invention has excellent curative, 5000 routine patients of treatment in recent years according to statistics, and effective percentage is 92.8%, cure rate is 76.3%, is subjected to generally that the patient welcomes and praises.
I. clinical data of the present invention
Random packet according to DME random packet principle, is divided treatment group and matched group.All cases are foundation by " People's Republic of China's pharmaceuticals industry standard " traditional Chinese medical science disease diagnosis criterion of therapeutical effect all, and establishing Chinese medicine of the present invention is the treatment group, and Pilulae Tongqiao Deafness is a matched group.
1500 examples are organized in treatment, sudden deafness 964 examples wherein, presbyacusis 346 examples, drug induced deafness 190 examples, the elder of medical history 30 years, the shortest person 10 days; Male's 910 examples wherein, women's 590 examples, maximum 79 years old age, minimal ages 3 years old.
Matched group: 240 examples, sudden deafness 128 examples wherein, presbyacusis 38 examples, drug induced deafness 74 examples, the elder of medical history 12 years, the shortest person 10 days; Male's 136 examples wherein, women's 104 examples, maximum 76 years old age, minimal ages 10 years old.
II. diagnosis basis and efficacy assessment standard.
1. diagnosis basis:
(1) sudden deafness: audition descends suddenly, and auditory dysesthesia peaks in 24～48 hours, mostly is the ears morbidity.Presbyacusis: onset is slow, and deaf degree day by day increases the weight of, with tinnitus and slightly dizzy.Drug induced deafness: audition descended at 2～3 days and peaks, because of audition can not get recovering to become permanent deafness for a long time.
(2) often cause a disease because of inducement such as angry, angry, tired, stress is excessive, frightened, heavy cold or unsuitable use ototoxic drugs, factor such as old.
(3) ear examination: the sudden deafness tympanum does not have significant change more or slight tympanum muddiness is arranged, and the tarnish of presbyacusis tympanum is caved in, and performance, the roughly same presbyacusis of drug induced deafness such as thickens.
(4) hearing test is the phonosensitive nerve deafness.
2. efficacy evaluation:
(1) recovery from illness: auditory rehabilitation is normal.
(2) take a turn for the better: audition improves more than 10 decibels.
(3) invalid: audition improves 10 decibels of less thaies, and nothing is clearly better.
III. therapeutic outcome:
Treatment group: sudden deafness 964 examples, 752 examples of fully recovering, cure rate 78%, 142 examples that take a turn for the better, improvement rate 14.7% invalid 70 examples, inefficiency 7.3%.Presbyacusis 346 examples, 217 examples of fully recovering, cure rate 62.7%, 98 examples that take a turn for the better, improvement rate 28.3%, invalid 31 examples, inefficiency 9%.Drug induced deafness 190 examples, 81 examples of fully recovering, cure rate 42.6%, 93 examples that take a turn for the better, improvement rate 48.9%, invalid 16 examples, inefficiency 8.5%.
Matched group: sudden deafness 128 examples, 15 examples of fully recovering, cure rate 11.7%, 24 examples that take a turn for the better, improvement rate 18.7%, invalid 89 examples, inefficiency 69.6%.Presbyacusis 38 examples, 3 examples of fully recovering, cure rate 7.9%, 8 examples that take a turn for the better, improvement rate 21%, invalid 27 examples, inefficiency 71.1%.Drug induced deafness 74 examples, 0 example of fully recovering, cure rate 0,3 examples that take a turn for the better, improvement rate 4.1%, invalid 71 examples, inefficiency 95.5%.
Above-mentioned data are listed table 1 in
| Grouping | Typing | The example number | Recovery from illness | Take a turn for the better | Invalid | |||
| The treatment group | Sudden deafness | 964 | 752 | 78％ | 142 | 14.7％ | 70 | 7.3％ |
| Presbyacusis | 346 | 217 | 62.7％ | 98 | 28.3％ | 31 | 9％ | |
| Drug induced deafness | 190 | 81 | 42.6％ | 93 | 48.9％ | 16 | 8.5％ | |
| Matched group | Sudden deafness | 128 | 15 | 11.7％ | 24 | 18.7％ | 89 | 69.6％ |
| Presbyacusis | 38 | 3 | 7.9％ | 8 | 21％ | 27 | 71.1％ | |
| Drug induced deafness | 74 | 0 | 0 | 3 | 4.1％ | 71 | 95.9％ | |
Treatment group and matched group are learned processing by statistics, and there were significant differences.
Wherein model case is as follows:
1. Wang, the man, 20 years old, unmarried, February 10 calendar year 2001, main suit: deafness and tinnitus three and half suddenly.Review medical history: suffered from Meniere disease, premorbid does not have obvious premonition, and the sense of dashing forward during morbidity is very dizzy, feels sick, and vomiting through certain hospitalize, is healed, but deafness and tinnitus occurred.Electric listening test: high frequency drops to 70 decibels, and tympanum, external auditory meatus, nasopharynx are all normal, diagnosis: sudden deafness and tinnitus, and through taking capsule for treating of the present invention, two courses of treatment, tinnitus disappears, and audition improves 40 decibels.
2. Liu, the man, 62 years old, married, on April 6th, 2002, main suit: right side tinnitus 6 months.Sound such as group Cicadae overhead pipe, and feel extremely painful, and the mood agitation is felt restless, and once in certain hospital's department of eye treatment, do not have any effect.Check: tympanum, external auditory meatus, nasopharynx are all normal, blood pressure 160/100mmhg, and diagnosis: nerve deafness tinnitus, through taking capsule for treating of the present invention, a course of treatment, symptom obviously alleviates, and two courses of treatment, tinnitus disappears, blood pressure 120/70mmhg
3. Zhang, the man, 62 years old, married, on August 10th, 2000, main suit: ears Hiccough and deaf 16 years.Sound is sometimes as the cicada cried, the sound that has the time image bus to cross, and auditory dysesthesia feels very painful, the mood agitation, review medical history: chronic otitis media, heal, the noise contact history is arranged, check: tympanum is complete, but depression, external auditory meatus has hyperemia, blood pressure 130/90mmhg, diagnosis: presbyacusis tinnitus, through taking capsule for treating of the present invention 20 days, tinnitus tone diminishes, audition increases, and two courses of treatment, tinnitus disappears, audition improves 30 decibels, and not recurrence is followed up a case by regular visits in three drug withdrawals course of treatment after 1 year.
4 Lee, the woman, 40 years old, married, on March 5th, 1998, main suit: deaf 20 years of ears.Review medical history: this patient's postnatal development is normal, and one-year-old half suffers from an inflammation of the lungs, and local certain doctor once used penicillin, and the streptomycin treatment causes losing audition, and that continues loses the linguistic competence, and once a lot of hospitalizes were all invalid.Check: 100 decibels of audition, diagnosis: drug induced deafness, aphasis is through taking capsule for treating of the present invention, a course of treatment, audition improves 20 decibels, and two courses of treatment, audition improves 40 decibels, can hear that others speaks up, take three courses of treatment, the linguistic competence recovers gradually.
5 Lee, woman, 40 years old, married, on October 15th, 1999, the main suit: left deafness and tinnitus is surplus half a year, review medical history: quarreled because of the man and wife before half a year,, fainted at that time on ground by husband's left ear of injuring, the left ear in back of waking up thunders and passes through as train, and check: the electric audiometry auris dextra is normal, 100 decibels in left ear, diagnosis: left trauma of ear induced deafness tinnitus, through taking capsule of the present invention, a course of treatment, audition improves 20 decibels, obeys three courses of treatment, and auditory rehabilitation is normal.
The pharmacology of the crude drug that the present invention uses:
Radix Rehmanniae Preparata: nourishing the blood and yin, vital essence replenishing and marrow benifiting; Fructus Corni: liver and kidney tonifying; Radix Scrophulariae: clearing away heat and nourishing YIN; Semen Sesami Nigrum: invigorating the liver and kidney, benefiting essence-blood, improve visual and auditory acuity; Four medicines match, enriching yin and nourishing kidney, and tonifying kidney-yin is to fill kidney qi, and kidney qi plentifully then audition is wise.Arillus Longan: invigorating the heart and spleen, nourishing blood to tranquillize the mind is the gentle tonic medicine of character; Dried Rhizoma Dioscoreae: supplementing QI and nourishing YIN, tonifying the lung spleen kidney; Endothelium Corneum Gigeriae Galli: the activating the spleen controlling nocturnal emission with astringent drugs that helps digestion; Semen Ziziphi Spinosae: tranquilizing by nourishing the heart; Magnetitum: subduing hyperactive YANG to ease mental disorders, hearing-improing and eyesight improving; Radix Bupleuri: the gas of the Chhnang of elevate a turnable ladder taste, six medicines match, regulating YIN and YANG, benefiting vital QI and blood, then ear get support, add that Flos Carthami has the merit of blood circulation and channel invigorating, can microcirculation improvement, promote the state of cochlea hypoxic-ischemic to be improved metabolism.Cornu Saigae Tataricae: suppressing the hyperactive liver to relieve the wind syndrome, heat clearing away arresting convulsion, the blood detoxifcation of loosing, the Radix Angelicae Dahuricae: the wind dehumidifying of loosing, understand things pain-stopping, detumescence and apocenosis; Two medicines match, heat-clearing and toxic substances removing, suppressing the hyperactive liver to relieve the wind syndrome, pulvis aromaticus wind, on reach disease institute, the heresy of the wind heat ear key of dispelling then is logical.Herba Saussureae Involueratae: strong muscle is active, and kidney invigorating and YANG supporting restores menstrual flow and invigorates blood circulation; Cordyceps: the kidney invigorating is reduced phlegm; Rhizoma Acori Graminei: eliminate phlegm for resuscitation; Rhizoma Alismatis: eliminating dampness by diuresis heat, the row phlegm retention, three medicines match, and can remove the pathology that adhesion thickens, and to promote the tympanum growth, adjust the function of pharyngotympanic tube.All medicine phases 5 become the nourishing kidney audition improvement altogether, invigorating QI and blood, and promoting blood circulation to remove obstruction in the collateral, eliminating evil sensible, promote cerebral blood flow, improve ear's blood circulation, repair injured acoustic nerve, tympanum recovers salpingian function.
Four. the specific embodiment:
Embodiment one: get 1 kilogram of Cornu Saigae Tataricae, 6 kilograms of Semen Ziziphi Spinosaes, 9 kilograms of dried Rhizoma Dioscoreaes, 8 kilograms of Radix Scrophulariae, 3 kilograms of Cordyceps, 5 kilograms of Rhizoma Acori Graminei, 9 kilograms of Magnetitums, 6 kilograms of Rhizoma Alismatis, 5 kilograms on Flos Carthami, 8 kilograms of Endothelium Corneum Gigeriae Galli mix oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 15 kilograms in Radix Rehmanniae Preparata, 9 kilograms of Fructus Corni add 292 kilograms in water, decoct twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization.
Usage and dosage: oral, be grown up each 10, three times on the one, after meal half an hour warm water delivery service.45 days is a course of treatment, and each course of treatment needn't be at interval, and can see remarkable result general 2～3 courses of treatment.
Points for attention: 1. avoid rareripe, living Bulbus Allii, Semen phaseoli radiati.
2. anemia of pregnant woman, the child should take under the doctor instructs.
Embodiment two: get 6 kilograms of Cornu Saigae Tataricae, 20 kilograms of Semen Ziziphi Spinosaes, 30 kilograms of dried Rhizoma Dioscoreaes, 30 kilograms of Radix Scrophulariae, 7 kilograms of Cordyceps, 15 kilograms of Rhizoma Acori Graminei, 20 kilograms of Magnetitums, 15 kilograms of Rhizoma Alismatis, 15 kilograms on Flos Carthami, 30 kilograms of Endothelium Corneum Gigeriae Galli mix oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 60 kilograms in Radix Rehmanniae Preparata, 30 kilograms of Fructus Corni, chopping adds 900 kilograms in water, decocts twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment three: get 4 kilograms of Cornu Saigae Tataricae, 12 kilograms of Semen Ziziphi Spinosaes, 20 kilograms of dried Rhizoma Dioscoreaes, 12 kilograms of Radix Scrophulariae, 15 kilograms of Cordyceps, 12 kilograms of Rhizoma Acori Graminei, 10 kilograms of Magnetitums, 10 kilograms of Rhizoma Alismatis, 9 kilograms on Flos Carthami, 20 kilograms of Endothelium Corneum Gigeriae Galli mix oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 30 kilograms in Radix Rehmanniae Preparata, 12 kilograms of Fructus Corni add 420 kilograms in water, decoct twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment four: get 3 kilograms of Cornu Saigae Tataricae, 10 kilograms of Semen Ziziphi Spinosaes, 17 kilograms of dried Rhizoma Dioscoreaes, 11 kilograms of Radix Scrophulariae, 4 kilograms of Cordyceps, 10 kilograms of Rhizoma Acori Graminei, 10 kilograms of Magnetitums, 9 kilograms of Rhizoma Alismatis, 8 kilograms on Flos Carthami, 16 kilograms of Endothelium Corneum Gigeriae Galli mix oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 22 kilograms in Radix Rehmanniae Preparata, 11 kilograms of Fructus Corni, chopping adds 330 kilograms in water, decocts twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment five: get 1 kilogram of Cornu Saigae Tataricae, 6 kilograms of Semen Ziziphi Spinosaes, 9 kilograms of dried Rhizoma Dioscoreaes, 8 kilograms of Radix Scrophulariae, 3 kilograms of Cordyceps, 5 kilograms of Rhizoma Acori Graminei, 9 kilograms of Magnetitums, 6 kilograms of Rhizoma Alismatis, 5 kilograms on Flos Carthami, 8 kilograms of Endothelium Corneum Gigeriae Galli, 3 kilograms of the Radixs Angelicae Dahuricae, 10 kilograms of Radix Bupleuri, 6 kilograms of Herba Saussureae Involueratae, Semen Sesami Nigrum mixes oven dry for 28 kilograms, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 15 kilograms in Radix Rehmanniae Preparata, 9 kilograms of Fructus Corni, 25 kilograms of Arillus Longans, chopping adds 392 kilograms in water, decocts twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment six: get 6 kilograms of Cornu Saigae Tataricae, 20 kilograms of Semen Ziziphi Spinosaes, 30 kilograms of dried Rhizoma Dioscoreaes, 30 kilograms of Radix Scrophulariae, 7 kilograms of Cordyceps, 15 kilograms of Rhizoma Acori Graminei, 20 kilograms of Magnetitums, 15 kilograms of Rhizoma Alismatis, 15 kilograms on Flos Carthami, 30 kilograms of Endothelium Corneum Gigeriae Galli, 8 kilograms of the Radixs Angelicae Dahuricae, 25 kilograms of Radix Bupleuri, 10 kilograms of Herba Saussureae Involueratae, Semen Sesami Nigrum mixes oven dry for 40 kilograms, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 60 kilograms in Radix Rehmanniae Preparata, 30 kilograms of Fructus Corni, 35 kilograms of Arillus Longans, chopping adds 1250 kilograms in water, decocts twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment seven: get 4 kilograms of Cornu Saigae Tataricae, 12 kilograms of Semen Ziziphi Spinosaes, 20 kilograms of dried Rhizoma Dioscoreaes, 12 kilograms of Radix Scrophulariae, 15 kilograms of Cordyceps, 12 kilograms of Rhizoma Acori Graminei, 10 kilograms of Magnetitums, 10 kilograms of Rhizoma Alismatis, 9 kilograms on Flos Carthami, 20 kilograms of Endothelium Corneum Gigeriae Galli, 6 kilograms of the Radixs Angelicae Dahuricae, 18 kilograms of Radix Bupleuri, 8 kilograms of Herba Saussureae Involueratae, Semen Sesami Nigrum mixes oven dry for 32 kilograms, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 30 kilograms in Radix Rehmanniae Preparata, 12 kilograms of Fructus Corni, 30 kilograms of choppings of Arillus Longan add 720 kilograms in water, decoct twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment eight: get 3 kilograms of Cornu Saigae Tataricae, 10 kilograms of Semen Ziziphi Spinosaes, 17 kilograms of dried Rhizoma Dioscoreaes, 11 kilograms of Radix Scrophulariae, 4 kilograms of Cordyceps, 10 kilograms of Rhizoma Acori Graminei, 10 kilograms of Magnetitums, 9 kilograms of Rhizoma Alismatis, 8 kilograms on Flos Carthami, 16 kilograms of Endothelium Corneum Gigeriae Galli, 5 kilograms of the Radixs Angelicae Dahuricae, 13 kilograms of Radix Bupleuri, 7 kilograms of Herba Saussureae Involueratae, 33 kilograms of Semen Sesami Nigrums mix oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 22 kilograms in Radix Rehmanniae Preparata, 11 kilograms of Fructus Corni, 29 kilograms of choppings of Arillus Longan add 558 kilograms in water, decoct twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment nine: get 2 kilograms of Cornu Saigae Tataricae, 8 kilograms of Semen Ziziphi Spinosaes, 13 kilograms of dried Rhizoma Dioscoreaes, 9 kilograms of Radix Scrophulariae, 4 kilograms of Cordyceps, 7 kilograms of Rhizoma Acori Graminei, 9 kilograms of Magnetitums, 7 kilograms of Rhizoma Alismatis, 6 kilograms on Flos Carthami, 12 kilograms of Endothelium Corneum Gigeriae Galli, 4 jin of the Radixs Angelicae Dahuricae, 12 kilograms of Radix Bupleuri, 7 kilograms of Herba Saussureae Involueratae, 31 kilograms of Semen Sesami Nigrums mix
Oven dry, pulverizing is the former medicine fine powders of 100～150 purposes; Get 18 kilograms in Radix Rehmanniae Preparata, 10 kilograms of Fructus Corni, 27 kilograms of choppings of Arillus Longan add 440 kilograms in water, decoct twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment ten: get 5 kilograms of Cornu Saigae Tataricae, 14 kilograms of Semen Ziziphi Spinosaes, 22 kilograms of dried Rhizoma Dioscoreaes, 17 kilograms of Radix Scrophulariae, 6 kilograms of Cordyceps, 13 kilograms of Rhizoma Acori Graminei, 12 kilograms of Magnetitums, 11 kilograms of Rhizoma Alismatis, 10 kilograms on Flos Carthami, 22 kilograms of Endothelium Corneum Gigeriae Galli, 6 kilograms of the Radixs Angelicae Dahuricae, 18 kilograms of Radix Bupleuri, 9 kilograms of Herba Saussureae Involueratae, 36 kilograms of Semen Sesami Nigrums mix oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 40 kilograms in Radix Rehmanniae Preparata, 16 kilograms of Fructus Corni, 31 kilograms of choppings of Arillus Longan add 870 kilograms in water, decoct twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment 11: get 5 jin of Cornu Saigae Tataricae, 18 kilograms of Semen Ziziphi Spinosaes, 28 kilograms of dried Rhizoma Dioscoreaes, 26 kilograms of Radix Scrophulariae, 7 kilograms of Cordyceps, 14 kilograms of Rhizoma Acori Graminei, 17 kilograms of Magnetitums, 14 kilograms of Rhizoma Alismatis, 14 kilograms on Flos Carthami, 28 kilograms of Endothelium Corneum Gigeriae Galli, 7 kilograms of the Radixs Angelicae Dahuricae, 22 kilograms of Radix Bupleuri, 9 kilograms of Herba Saussureae Involueratae, 39 kilograms of Semen Sesami Nigrums mix oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 50 kilograms in Radix Rehmanniae Preparata, 25 kilograms of Fructus Corni, 34 kilograms of choppings of Arillus Longan add 1090 kilograms in water, decoct twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment 12: get 1 kilogram of Cornu Saigae Tataricae, 10 kilograms of Semen Ziziphi Spinosaes, 9 kilograms of dried Rhizoma Dioscoreaes, 11 kilograms of Radix Scrophulariae, 4 kilograms of Cordyceps, 9 kilograms of Rhizoma Acori Graminei, 9 kilograms of Magnetitums, 8 kilograms of Rhizoma Alismatis, 7 kilograms on Flos Carthami, 15 kilograms of Endothelium Corneum Gigeriae Galli, 4 kilograms of the Radixs Angelicae Dahuricae, 11 kilograms of Radix Bupleuri, 7 kilograms of Herba Saussureae Involueratae, 32 kilograms of Semen Sesami Nigrums mix oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 20 kilograms in Radix Rehmanniae Preparata, 10 kilograms of Fructus Corni, 28 kilograms of choppings of Arillus Longan add 464 kilograms in water, decoct twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment 13: get 4 kilograms of Cornu Saigae Tataricae, 6 kilograms of Semen Ziziphi Spinosaes, 20 kilograms of dried Rhizoma Dioscoreaes, 8 kilograms of Radix Scrophulariae, 5 kilograms of Cordyceps, 12 kilograms of Rhizoma Acori Graminei, 10 kilograms of Magnetitums, 10 kilograms of Rhizoma Alismatis, 9 kilograms on Flos Carthami, 8 kilograms of Endothelium Corneum Gigeriae Galli, 3 kilograms of the Radixs Angelicae Dahuricae, 10 kilograms of Radix Bupleuri, 8 kilograms of Herba Saussureae Involueratae, 28 kilograms of Semen Sesami Nigrums mix oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 15 kilograms in Radix Rehmanniae Preparata, 12 kilograms of Fructus Corni, 20 kilograms of choppings of Arillus Longan add 376 kilograms in water, decoct twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment 14: get 5 kilograms of Cornu Saigae Tataricae, 18 kilograms of Semen Ziziphi Spinosaes, 28 kilograms of dried Rhizoma Dioscoreaes, 17 kilograms of Radix Scrophulariae, 6 kilograms of Cordyceps, 13 kilograms of Rhizoma Acori Graminei, 15 kilograms of Magnetitums, 6 kilograms of Rhizoma Alismatis, 12 kilograms on Flos Carthami, 22 kilograms of Endothelium Corneum Gigeriae Galli, 7 kilograms of the Radixs Angelicae Dahuricae, 10 kilograms of Radix Bupleuri, 6 kilograms of Herba Saussureae Involueratae, 37 kilograms of Semen Sesami Nigrums mix oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 40 kilograms in Radix Rehmanniae Preparata, 21 kilograms of Fructus Corni, 31 kilograms of choppings of Arillus Longan add 920 kilograms in water, decoct twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment 15: get 6 kilograms of Cornu Saigae Tataricae, 6 kilograms of Semen Ziziphi Spinosaes, 38 kilograms of dried Rhizoma Dioscoreaes, 8 kilograms of Radix Scrophulariae, 7 kilograms of Cordyceps, 15 kilograms of Rhizoma Acori Graminei, 20 kilograms of Magnetitums, 15 kilograms of Rhizoma Alismatis, 15 kilograms on Flos Carthami, 8 kilograms of Endothelium Corneum Gigeriae Galli, 8 kilograms of the Radixs Angelicae Dahuricae, 10 kilograms of Radix Bupleuri, 6 kilograms of Herba Saussureae Involueratae, 28 kilograms of Semen Sesami Nigrums mix oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 15 kilograms in Radix Rehmanniae Preparata, 9 kilograms of Fructus Corni, 25 kilograms of choppings of Arillus Longan add 392 kilograms in water, decoct twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment 16: get 3 kilograms of Cornu Saigae Tataricae, 10 kilograms of Semen Ziziphi Spinosaes, 13 kilograms of dried Rhizoma Dioscoreaes, 9 kilograms of Radix Scrophulariae, 4 kilograms of Cordyceps, 10 kilograms of Rhizoma Acori Graminei, 9 kilograms of Magnetitums, 9 kilograms of Rhizoma Alismatis, 6 kilograms on Flos Carthami, 16 kilograms of Endothelium Corneum Gigeriae Galli, 4 kilograms of the Radixs Angelicae Dahuricae, 12 kilograms of Radix Bupleuri, 7 kilograms of Herba Saussureae Involueratae, 33 kilograms of Semen Sesami Nigrums mix oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 20 kilograms in Radix Rehmanniae Preparata, 11 kilograms of Fructus Corni, 29 kilograms of choppings of Arillus Longan add 531 kilograms in water, decoct twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment 17: get 4 kilograms of Cornu Saigae Tataricae, 12 kilograms of Semen Ziziphi Spinosaes, 13 kilograms of dried Rhizoma Dioscoreaes, 12 kilograms of Radix Scrophulariae, 5 kilograms of Cordyceps, 9 kilograms of Rhizoma Acori Graminei, 10 kilograms of Magnetitums, 9 kilograms of Rhizoma Alismatis, 9 kilograms on Flos Carthami, 12 kilograms of Endothelium Corneum Gigeriae Galli, 5 kilograms of the Radixs Angelicae Dahuricae, 12 kilograms of Radix Bupleuri, 8 kilograms of Herba Saussureae Involueratae, 31 kilograms of Semen Sesami Nigrums mix oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 18 kilograms in Radix Rehmanniae Preparata, 12 kilograms of Fructus Corni, 30 kilograms of choppings of Arillus Longan add 540 kilograms in water, decoct twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, oven dry, fully mixing incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment 18: get 2 kilograms of Cornu Saigae Tataricae, 8 kilograms of Semen Ziziphi Spinosaes, 28 kilograms of dried Rhizoma Dioscoreaes, 9 kilograms of Radix Scrophulariae, 6 kilograms of Cordyceps, 14 kilograms of Rhizoma Acori Graminei, 9 kilograms of Magnetitums, 14 kilograms of Rhizoma Alismatis, 12 kilograms on Flos Carthami, 6 kilograms of Endothelium Corneum Gigeriae Galli, 7 kilograms of the Radixs Angelicae Dahuricae, 20 kilograms of Radix Bupleuri, 9 kilograms of Herba Saussureae Involueratae, 31 kilograms of Semen Sesami Nigrums mix oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 45 kilograms in Radix Rehmanniae Preparata, 21 kilograms of Fructus Corni, 27 kilograms of choppings of Arillus Longan add 930 kilograms in water, decoct twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Embodiment 19: get 6 kilograms of Cornu Saigae Tataricae, 8 kilograms of Semen Ziziphi Spinosaes, 30 kilograms of dried Rhizoma Dioscoreaes, 9 kilograms of Radix Scrophulariae, 7 kilograms of Cordyceps, 7 kilograms of Rhizoma Acori Graminei, 20 kilograms of Magnetitums, 7 kilograms of Rhizoma Alismatis, 15 kilograms on Flos Carthami, 30 kilograms of Endothelium Corneum Gigeriae Galli, 8 kilograms of the Radixs Angelicae Dahuricae, 12 kilograms of Radix Bupleuri, 7 kilograms of Herba Saussureae Involueratae, 40 kilograms of Semen Sesami Nigrums mix oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; Get 60 kilograms in Radix Rehmanniae Preparata, 10 kilograms of Fructus Corni, 27 kilograms of choppings of Arillus Longan add 970 kilograms in water, decoct twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, fully mixing is dried, and incapsulates each capsule 0.3g after the sterilization.
Usage and dosage and points for attention do not repeat with embodiment one.
Claims (8)
1. Chinese patent medicine for the treatment of Hiccough and deaf, it is characterized in that: containing with the weight portion is the following bulk drugs of unit, 1～6 part of Cornu Saigae Tataricae, 6～20 parts of Semen Ziziphi Spinosaes, 9～30 parts of dried Rhizoma Dioscoreaes, 15～60 parts in Radix Rehmanniae Preparata, 9～30 parts of Fructus Corni, 8～30 parts of Radix Scrophulariae, 3～7 parts of Cordyceps, 5～15 parts of Rhizoma Acori Graminei, 9～20 parts of Magnetitums, 6～15 parts of Rhizoma Alismatis, 5～15 parts on Flos Carthami, 8～30 parts of Endothelium Corneum Gigeriae Galli.
2. Chinese patent medicine according to claim 1 is characterized in that: wherein Cornu Saigae Tataricae is 1～4 part, 10～15 parts of Semen Ziziphi Spinosaes, 15～25 parts of dried Rhizoma Dioscoreaes, 25～48 parts in Radix Rehmanniae Preparata, 14～28 parts of Fructus Corni, 10～24 parts of Radix Scrophulariae, 3～6 parts of Cordyceps, 7～12 parts of Rhizoma Acori Graminei, 9～15 parts of Magnetitums, 8～12 parts of Rhizoma Alismatis, 7～13 parts on Flos Carthami, 14～22 parts of Endothelium Corneum Gigeriae Galli.
3. according to the described Chinese patent medicine of claim 2, it is characterized in that: wherein Cornu Saigae Tataricae is 1～4 part, 10～13 parts of Semen Ziziphi Spinosaes, 18～25 parts of dried Rhizoma Dioscoreaes, 25～40 parts in Radix Rehmanniae Preparata, 18～25 parts of Fructus Corni, 12～15 parts of Radix Scrophulariae, 3～6 parts of Cordyceps, 10～12 parts of Rhizoma Acori Graminei, 12～15 parts of Magnetitums, 8～12 parts of Rhizoma Alismatis, 9～12 parts on Flos Carthami, 16～20 parts of Endothelium Corneum Gigeriae Galli.
4. according to claim 1, or 2, or 3 described Chinese patent medicines, it is characterized in that: also contain 3～8 parts of the Radixs Angelicae Dahuricae, 10～25 parts of Radix Bupleuri, 6～10 parts of Herba Saussureae Involueratae, 25～35 parts of Arillus Longans, 28～40 parts of Semen Sesami Nigrums.
5. according to the described Chinese patent medicine of any one right in the claim 1～3, it is characterized in that: with the crude drug Cornu Saigae Tataricae, Semen Ziziphi Spinosae, dried Rhizoma Dioscoreae, Radix Scrophulariae, Cordyceps, Rhizoma Acori Graminei, Magnetitum, Rhizoma Alismatis, Flos Carthami, Endothelium Corneum Gigeriae Galli is got part by proportioning, mixes oven dry, and pulverizing is the former medicine fine powders of 100～150 purposes; With the crude drug Radix Rehmanniae Preparata, Fructus Corni is got a part chopping by proportioning, adds 8～10 times in water, decocts twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, abundant mixing, oven dry, sterilization.
6. Chinese patent medicine according to claim 4 is characterized in that: with crude drug Cornu Saigae Tataricae, Semen Ziziphi Spinosae, dried Rhizoma Dioscoreae, Radix Scrophulariae, Cordyceps, Rhizoma Acori Graminei, Magnetitum, Rhizoma Alismatis, Flos Carthami, Endothelium Corneum Gigeriae Galli, the Radix Angelicae Dahuricae, Radix Bupleuri, Herba Saussureae Involueratae, Semen Sesami Nigrum is got part by proportioning, mix oven dry, pulverizing is the former medicine fine powders of 100～150 purposes; With the crude drug Radix Rehmanniae Preparata, Fructus Corni, Arillus Longan is got a part chopping by proportioning, adds 8～10 times in water, decocts twice, and each 1 hour, twice filtrate is merged, add former medicine fine powder, abundant mixing, oven dry, sterilization.
7. Chinese Traditional Medicines according to claim 5 is characterized in that: this medicament is a powder, or is capsule, or is pill.
8. Chinese Traditional Medicines according to claim 6 is characterized in that: this medicament is a powder, or is capsule, or is pill.
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| CN118141864A (en) * | 2024-03-11 | 2024-06-07 | 广东省耳康医学研究中心 | A Chinese medicine composition for treating deafness and tinnitus and its preparation method |
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| CN100372560C (en) * | 2003-07-20 | 2008-03-05 | 罗侠 | Medicine for treating congenital deafmutism |
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| CN101439131B (en) * | 2007-11-20 | 2011-05-25 | 上海中医药大学 | Traditional Chinese medicine composition for treating sensorineural deafness and its application |
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| CN101766792B (en) * | 2010-04-20 | 2011-06-15 | 泰一和浦（北京）中医药研究院有限公司 | Chinese herbal composite for deafness treatment and preparation method thereof |
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| CN105327047A (en) * | 2015-11-25 | 2016-02-17 | 刘文君 | Medicine for treating nerve deafness and tinnitus |
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| CN118141864A (en) * | 2024-03-11 | 2024-06-07 | 广东省耳康医学研究中心 | A Chinese medicine composition for treating deafness and tinnitus and its preparation method |
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