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CN1741994A - 作为趋化因子受体调节剂的3－氨基吡咯烷衍生物 - Google Patents

作为趋化因子受体调节剂的3－氨基吡咯烷衍生物 Download PDF

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Publication number
CN1741994A
CN1741994A CN 200380109198 CN200380109198A CN1741994A CN 1741994 A CN1741994 A CN 1741994A CN 200380109198 CN200380109198 CN 200380109198 CN 200380109198 A CN200380109198 A CN 200380109198A CN 1741994 A CN1741994 A CN 1741994A
Authority
CN
China
Prior art keywords
amino
base
trifluoromethyl
tetramethyleneimine
benzamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN 200380109198
Other languages
English (en)
Chinese (zh)
Inventor
薛楚标
B·梅特卡尔夫
冯皓
曹敢峰
黄太生
郑长胜
D·J·罗宾逊
A·Q·韩
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Priority to CN201110045106.XA priority Critical patent/CN102153539B/zh
Publication of CN1741994A publication Critical patent/CN1741994A/zh
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN 200380109198 2002-11-27 2003-11-26 作为趋化因子受体调节剂的3－氨基吡咯烷衍生物 Pending CN1741994A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201110045106.XA CN102153539B (zh) 2002-11-27 2003-11-26 作为趋化因子受体调节剂的3-氨基吡咯烷衍生物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42960502P 2002-11-27 2002-11-27
US60/429,605 2002-11-27
US60/463,976 2003-04-18

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201110045106.XA Division CN102153539B (zh) 2002-11-27 2003-11-26 作为趋化因子受体调节剂的3-氨基吡咯烷衍生物

Publications (1)

Publication Number Publication Date
CN1741994A true CN1741994A (zh) 2006-03-01

Family

ID=36093944

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 200380109198 Pending CN1741994A (zh) 2002-11-27 2003-11-26 作为趋化因子受体调节剂的3－氨基吡咯烷衍生物

Country Status (3)

Country Link
CN (1) CN1741994A (uk)
UA (1) UA87449C2 (uk)
ZA (1) ZA200504322B (uk)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102317278A (zh) * 2008-12-10 2012-01-11 詹森药业有限公司 Ccr2的4-氮杂环丁烷基-1-杂芳基-环己醇拮抗剂
CN102459225A (zh) * 2009-04-16 2012-05-16 詹森药业有限公司 Ccr2的4-氮杂环丁烷基-1-杂芳基-环己烷拮抗剂
CN102459226A (zh) * 2009-04-17 2012-05-16 詹森药业有限公司 Ccr2的4-氮杂环丁烷基-1-杂原子连接的-环己烷拮抗剂
CN102459227A (zh) * 2009-04-17 2012-05-16 詹森药业有限公司 Ccr2的4-氮杂环丁烷基-1-苯基-环己烷拮抗剂
CN102933575A (zh) * 2010-06-09 2013-02-13 詹森药业有限公司 Ccr2的环己基-氮杂环丁烷基拮抗剂
CN103097375A (zh) * 2010-06-17 2013-05-08 詹森药业有限公司 Ccr2的环己基-氮杂环丁烷拮抗剂
WO2025092991A1 (zh) * 2023-11-03 2025-05-08 中国科学院上海药物研究所 趋化因子受体2拮抗剂在制备治疗糖尿病并发焦虑症的应用

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102317278A (zh) * 2008-12-10 2012-01-11 詹森药业有限公司 Ccr2的4-氮杂环丁烷基-1-杂芳基-环己醇拮抗剂
CN102459225A (zh) * 2009-04-16 2012-05-16 詹森药业有限公司 Ccr2的4-氮杂环丁烷基-1-杂芳基-环己烷拮抗剂
CN102459225B (zh) * 2009-04-16 2014-08-20 詹森药业有限公司 Ccr2的4-氮杂环丁烷基-1-杂芳基-环己烷拮抗剂
CN102459226A (zh) * 2009-04-17 2012-05-16 詹森药业有限公司 Ccr2的4-氮杂环丁烷基-1-杂原子连接的-环己烷拮抗剂
CN102459227A (zh) * 2009-04-17 2012-05-16 詹森药业有限公司 Ccr2的4-氮杂环丁烷基-1-苯基-环己烷拮抗剂
CN102459227B (zh) * 2009-04-17 2014-08-20 詹森药业有限公司 Ccr2的4-氮杂环丁烷基-1-苯基-环己烷拮抗剂
CN102459226B (zh) * 2009-04-17 2014-09-17 詹森药业有限公司 Ccr2的4-氮杂环丁烷基-1-杂原子连接的-环己烷拮抗剂
CN102933575A (zh) * 2010-06-09 2013-02-13 詹森药业有限公司 Ccr2的环己基-氮杂环丁烷基拮抗剂
CN102933575B (zh) * 2010-06-09 2015-02-04 詹森药业有限公司 Ccr2的环己基-氮杂环丁烷基拮抗剂
CN103097375A (zh) * 2010-06-17 2013-05-08 詹森药业有限公司 Ccr2的环己基-氮杂环丁烷拮抗剂
CN103097375B (zh) * 2010-06-17 2015-08-12 詹森药业有限公司 Ccr2的环己基-氮杂环丁烷拮抗剂
WO2025092991A1 (zh) * 2023-11-03 2025-05-08 中国科学院上海药物研究所 趋化因子受体2拮抗剂在制备治疗糖尿病并发焦虑症的应用

Also Published As

Publication number Publication date
UA87449C2 (uk) 2009-07-27
ZA200504322B (en) 2006-02-22

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Open date: 20060301