CN1616041A - Chinese medicine composition for treating chronic ulcerative colitis - Google Patents
Chinese medicine composition for treating chronic ulcerative colitis Download PDFInfo
- Publication number
- CN1616041A CN1616041A CN 200410078380 CN200410078380A CN1616041A CN 1616041 A CN1616041 A CN 1616041A CN 200410078380 CN200410078380 CN 200410078380 CN 200410078380 A CN200410078380 A CN 200410078380A CN 1616041 A CN1616041 A CN 1616041A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- ulcerative colitis
- medicine composition
- radix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 38
- 206010009900 Colitis ulcerative Diseases 0.000 title claims abstract description 13
- 201000006704 Ulcerative Colitis Diseases 0.000 title claims abstract description 13
- 230000001684 chronic effect Effects 0.000 title claims abstract description 13
- 239000000203 mixture Substances 0.000 title claims abstract description 13
- 241000756943 Codonopsis Species 0.000 claims description 10
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 10
- 229940079593 drug Drugs 0.000 claims description 9
- 241000545442 Radix Species 0.000 claims description 6
- 230000000694 effects Effects 0.000 abstract description 15
- 238000002360 preparation method Methods 0.000 abstract description 15
- 230000001737 promoting effect Effects 0.000 abstract description 7
- 208000025865 Ulcer Diseases 0.000 abstract description 6
- 231100000397 ulcer Toxicity 0.000 abstract description 6
- 238000005469 granulation Methods 0.000 abstract description 5
- 230000003179 granulation Effects 0.000 abstract description 5
- 210000004369 blood Anatomy 0.000 abstract description 2
- 239000008280 blood Substances 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract description 2
- 241000132012 Atractylodes Species 0.000 abstract 1
- 241000736199 Paeonia Species 0.000 abstract 1
- 235000006484 Paeonia officinalis Nutrition 0.000 abstract 1
- 229940107666 astragalus root Drugs 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 238000011069 regeneration method Methods 0.000 abstract 1
- 239000009636 Huang Qi Substances 0.000 description 6
- 230000000968 intestinal effect Effects 0.000 description 4
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 239000004480 active ingredient Substances 0.000 description 3
- 208000010643 digestive system disease Diseases 0.000 description 3
- -1 electuary Substances 0.000 description 3
- 230000002607 hemopoietic effect Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 238000001802 infusion Methods 0.000 description 2
- 210000004347 intestinal mucosa Anatomy 0.000 description 2
- 208000037920 primary disease Diseases 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 244000293323 Cosmos caudatus Species 0.000 description 1
- 235000005956 Cosmos caudatus Nutrition 0.000 description 1
- 241000792859 Enema Species 0.000 description 1
- 240000004670 Glycyrrhiza echinata Species 0.000 description 1
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 description 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 description 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 206010020565 Hyperaemia Diseases 0.000 description 1
- 206010061297 Mucosal erosion Diseases 0.000 description 1
- 206010028140 Mucous stools Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 241000180649 Panax notoginseng Species 0.000 description 1
- 235000003143 Panax notoginseng Nutrition 0.000 description 1
- 206010057071 Rectal tenesmus Diseases 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 241001078983 Tetradium ruticarpum Species 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 206010009887 colitis Diseases 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 239000007920 enema Substances 0.000 description 1
- 229940095399 enema Drugs 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 229940010454 licorice Drugs 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 239000009806 pulsatillae Substances 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 206010040872 skin infection Diseases 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 208000012271 tenesmus Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of Chinese medicine composition for treating chronic ulcerative colitis, and belongs to the field of Chinese medicine technology. The Chinese medicine composition is prepared with eight kinds of Chinese medicinal materials, including astragalus root, white atractylodes rhizome, haw, Dangshen, red peony root, etc. The medicine of the present invention is prepared in various preparation forms for easy taking. The medicine has the excellent effect of promoting granulation, promoting blood regeneration and promoting ulcer to heal and has high effective rate.
Description
[technical field]
The present invention relates to a kind of Chinese medicine composition for the treatment of chronic ulcerative colitis, belong to the field of Chinese medicines.
[background technology]
Chronic ulcerative colitis is a kind of clinically common digestive system disease, and present western medicine produces effects very few, and side effect is many, easily recurrence.The therapeutic modality of Chinese medicine is a lot of at present, for example: application number: 98100231, denomination of invention " a kind of medicine for the treatment of chronic ulcerative colitis and preparation method thereof ", it is mainly formed by medical material infusions such as Radix Notoginseng, Margarita, Endoconcha Sepiae, Fructus Evodiaes.Effectively improve local microcirculation, dredge the meridian passage, putrefaction-removing granulation-promoting, protection ulcer surface are to reach therapeutic purposes; And for example: application number: 03101319, denomination of invention " a kind of colitis enema ", it be Herba Agrimoniae, the Radix Pulsatillae, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Radix Sophorae Flavescentis, licorice, Pericarpium Papaveris, the Pseudobulbus Bletillae (Rhizoma Bletillae), etc. composition.Effect with sterilization detoxifcation, removing the necrotic tissue and promoting granulation, hemostasis antidiarrhea and analgesic.However, treatment does not still have specific medicament for chronic ulcerative colitis, and the curative effect of medicine of the prior art still can not be satisfactory.
[summary of the invention]
Therefore, still there is the vast market demand in people for the treatment chronic ulcerative colitis pharmaceutical preparation of better efficacy, and particularly curative effect is reliable, and it is fast that clinical symptoms is recovered, cure rate height, the Chinese medicine preparation that toxicity, side effect is relatively little.Up to the present, still find no the data of any destruction novelty of the present invention, present inventor people is through studying intensively for many years, by clinical practice and checking repeatedly, a large amount of clinical observation materials have been collected, obtained to the treatment chronic ulcerative colitis have the Chinese medicine composition of better curative effect, thereby finished the present invention.
Purpose of the present invention is exactly that a kind of Chinese medicine composition for the treatment of chronic ulcerative colitis with better curative effect will be provided.
The present invention is achieved in that it mainly is to be made by following bulk drugs: the Radix Astragali, Rhizoma Atractylodis Macrocephalae (parched), Fructus Crataegi, Radix Codonopsis, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Poria, Rhizoma Coptidis.
Drug component consumption of the present invention is that the following weight parts scope all has better curative effect:
30～70 parts of the Radixs Astragali, 10～40 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 10～40 parts of Fructus Crataegis, 10～40 parts of Radix Codonopsis, 5～20 parts of Radix Paeoniae Rubra, 5～20 parts of the Radix Paeoniae Albas, 5～20 parts of Poria, 5～20 parts of Rhizoma Coptidis.
Be preferably: 50 parts of the Radixs Astragali, 30 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts of Fructus Crataegis, 30 parts of Radix Codonopsis, 15 parts of Radix Paeoniae Rubra, 15 parts of the Radix Paeoniae Albas, 10 parts of Poria, 10 parts of Rhizoma Coptidis.
Preparation technology uses " specification requirement of new Chinese medicine Study on Preparation " in principle, the effective constituent that mainly contains that uses modern preparation new technique to extract medicine is used as medicine, add some accessory substances,, can be made into capsule, electuary, tablet, oral liquid as water, sugar, starch etc.
Chinese medicine composition is decocted in water for oral dose, and every part is adopted gram to be unit, and every day, potion divided secondary to take, and two weeks were a course of treatment.
Medicine of the present invention is made other dosage forms, conveniently takes, and medication the longest 4 courses of treatment, the shortest 2 courses of treatment, to inside ulcer, do not hold back mouthful person for a long time and play the effect that the granulation promoting hemopoietic is put on flesh equally, the function of impelling ulcer healing is promptly arranged, total effective rate 92%.
[specific embodiment]
The present invention is described further by clinical observation test and embodiment.
Test example 1, clinical observation on the therapeutic effect data
Chronic ulcerative colitis is a kind of clinically common digestive system disease, and present western medicine produces effects very few, and side effect is many, and recurrence is many, and we adopt from intending Chinese medicine decoction and treat 68 examples, and satisfactory efficacy is now reported the result as follows:
1, physical data: this is organized 68 routine patients and all makes a definite diagnosis through enteroscopy, and all cases meet national digestive disease diagnostic criteria in 78 years, wherein male 38 examples, woman's 30 examples, minimum 22 years old of age, maximum 67 years old, the course of disease is the longest 11 years, and is the shortest 1.5 years, all accepts Western medicine or other treatment is invalid.Mainly show with dense hemafecia, Mucous Stool or hemafecia.Often with characteristics such as tenesmus, part is with inappetence, weak, nauseating, anemia, 1～4/HP of stool laboratory leukocyte, 3～5/HP of erythrocyte, mucous hyperemia under the intestinal mirror, edema, coarse rough, the pus tongue is all adhered on the intestinal mucosa surface, mucosal erosion, touch easily hemorrhage, stool is cultivated all negative.
2, Therapeutic Method: adopt from intending multiple intestinal soup decoction.Every day, potion divided secondary to take, and two weeks were a course of treatment, and prescription is as follows:
Radix Astragali 50g, Rhizoma Atractylodis Macrocephalae (parched), Fructus Crataegi, each 30g of Radix Codonopsis, Radix Paeoniae Rubra, each 15g of the Radix Paeoniae Alba, Poria, each 10g of Rhizoma Coptidis.
3, therapeutic outcome:
68 examples are cured 43 examples (symptom complete obiteration, stool routine examination are normal, enteroscopy intestinal mucosa recover normal); Produce effects 19 examples (symptom disappears substantially, stool routine examination is normal, and the intestinal mirror partly recovers); Invalid 5 examples (symptom no change); Improvement example 1 example, total effective rate 92%, medication the longest 4 courses of treatment, the shortest 2 courses of treatment.
4, know from experience: the traditional Chinese medical science claims " intestinal is out-of-the-way " to primary disease, and the common coldheat complex of primary disease, deficiency and excess see that also qi depression to blood stasis adopts the treatment by Chinese herbs cold and heat, reinforcement and elimination in combination with existing.Can wet three warmers, strong taste, hemopoietic granulation promoting, evacuation of pus expelling the toxic substance from the body with tonic of the Radix Astragali among the we, the Radix Astragali not only can be controlled human body skin table skin infection, and to inside ulcer, do not hold back mouthful person for a long time and play the effect that the granulation promoting hemopoietic is put on flesh equally, the function of impelling ulcer healing is promptly arranged.So we are worth clinical further research and application.
Embodiment 1: the preparation of electuary type of the present invention
Getting each composition bulk drugs is: 50 parts of the Radixs Astragali, 30 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts of Fructus Crataegis, 30 parts of Radix Codonopsis, 15 parts of Radix Paeoniae Rubra, 15 parts of the Radix Paeoniae Albas, 10 parts of Poria, 10 parts of Rhizoma Coptidis.
Preparation technology meets " specification requirement of new Chinese medicine Study on Preparation " in principle, use modern preparation new technique, said medicine dried be crushed to more than 100 orders, add some accessory substances, through decocting, concentrate, technology infusion such as mixing forms, every bag 10 grams of preparation electuary, per three comprise the suitable Radix Astragali 50 grams, Rhizoma Atractylodis Macrocephalae (parched) 30 grams, Fructus Crataegi 30 grams, Radix Codonopsis 30 grams, Radix Paeoniae Rubra 15 grams, the Radix Paeoniae Alba 15 grams, the active ingredient of Poria 10 grams, Rhizoma Coptidis 10 grams.
Embodiment 2: the preparation of oral agents dosage form of the present invention.
Getting each composition bulk drugs is: 50 parts of the Radixs Astragali, 30 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts of Fructus Crataegis, 30 parts of Radix Codonopsis, 15 parts of Radix Paeoniae Rubra, 15 parts of the Radix Paeoniae Albas, 10 parts of Poria, 10 parts of Rhizoma Coptidis.
Preparation technology meets " specification requirement of new Chinese medicine Study on Preparation " in principle, said medicine is used modern preparation new technique, add some accessory substances, extract active ingredient and prepare oral agents, by the suitable Radix Astragali 50 grams of per three bottles of effective doses, Rhizoma Atractylodis Macrocephalae (parched) 30 grams, Fructus Crataegi 30 grams, Radix Codonopsis 30 grams, Radix Paeoniae Rubra 15 grams, the Radix Paeoniae Alba 15 grams, the active ingredient of Poria 10 grams, Rhizoma Coptidis 10 grams is calculated.
Claims (2)
1, a kind of Chinese medicine composition for the treatment of chronic ulcerative colitis, it is characterized in that it mainly is to be made by following bulk drugs: 30～70 parts of the Radixs Astragali, 10～40 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 10～40 parts of Fructus Crataegis, 10～40 parts of Radix Codonopsis, 5～20 parts of Radix Paeoniae Rubra, 5～20 parts of the Radix Paeoniae Albas, 5～20 parts of Poria, 5～20 parts of Rhizoma Coptidis.
2, a kind of Chinese medicine composition for the treatment of chronic ulcerative colitis according to claim 1, it is characterized in that wherein the consumption of crude drug is: 50 parts of the Radixs Astragali, 30 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts of Fructus Crataegis, 30 parts of Radix Codonopsis, 15 parts of Radix Paeoniae Rubra, 15 parts of the Radix Paeoniae Albas, 10 parts of Poria, 10 parts of Rhizoma Coptidis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410078380 CN1616041A (en) | 2004-09-27 | 2004-09-27 | Chinese medicine composition for treating chronic ulcerative colitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410078380 CN1616041A (en) | 2004-09-27 | 2004-09-27 | Chinese medicine composition for treating chronic ulcerative colitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1616041A true CN1616041A (en) | 2005-05-18 |
Family
ID=34765493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410078380 Pending CN1616041A (en) | 2004-09-27 | 2004-09-27 | Chinese medicine composition for treating chronic ulcerative colitis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1616041A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1857453B (en) * | 2006-03-03 | 2010-05-12 | 延边大学 | A traditional Chinese medicine composition for treating ulcerative colitis and its preparation method |
| CN102370687A (en) * | 2011-11-17 | 2012-03-14 | 中国中医科学院中医临床基础医学研究所 | Compound Chinese medicinal preparation for treating colonitis and preparation method thereof |
| CN102008565B (en) * | 2009-09-07 | 2012-05-23 | 成都中医药大学 | A kind of pharmaceutical composition for treating ulcerative colitis and preparation method thereof |
| CN103893457A (en) * | 2014-03-31 | 2014-07-02 | 王红 | Traditional Chinese medicine for treating ulcerative colitis |
| CN104436088A (en) * | 2013-09-18 | 2015-03-25 | 香港浸会大学 | A kind of Chinese herbal medicine formula for treating inflammatory bowel disease and preparation method thereof |
| CN105998264A (en) * | 2016-06-19 | 2016-10-12 | 练燕华 | Traditional Chinese medicine for treating chronic ulcerative colitis |
-
2004
- 2004-09-27 CN CN 200410078380 patent/CN1616041A/en active Pending
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1857453B (en) * | 2006-03-03 | 2010-05-12 | 延边大学 | A traditional Chinese medicine composition for treating ulcerative colitis and its preparation method |
| CN102008565B (en) * | 2009-09-07 | 2012-05-23 | 成都中医药大学 | A kind of pharmaceutical composition for treating ulcerative colitis and preparation method thereof |
| CN102370687A (en) * | 2011-11-17 | 2012-03-14 | 中国中医科学院中医临床基础医学研究所 | Compound Chinese medicinal preparation for treating colonitis and preparation method thereof |
| CN102370687B (en) * | 2011-11-17 | 2017-12-08 | 中国中医科学院中医临床基础医学研究所 | A kind of compound Chinese medicinal preparation for treating colitis and preparation method thereof |
| CN104436088A (en) * | 2013-09-18 | 2015-03-25 | 香港浸会大学 | A kind of Chinese herbal medicine formula for treating inflammatory bowel disease and preparation method thereof |
| CN104436088B (en) * | 2013-09-18 | 2017-10-13 | 香港浸会大学 | Chinese herbal medicine formula for treating inflammatory bowel disease and preparation method thereof |
| CN103893457A (en) * | 2014-03-31 | 2014-07-02 | 王红 | Traditional Chinese medicine for treating ulcerative colitis |
| CN103893457B (en) * | 2014-03-31 | 2018-04-17 | 王红 | One kind treats ulcerative colitis Chinese medicine |
| CN105998264A (en) * | 2016-06-19 | 2016-10-12 | 练燕华 | Traditional Chinese medicine for treating chronic ulcerative colitis |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1103223C (en) | Chinese medicine for treating cholecystitis | |
| CN1507884A (en) | Traditional Chinese medicine powder and decoction composition for treating cancer | |
| CN1172672A (en) | Chinese medicinal herb composition for treating cancer | |
| CN1616041A (en) | Chinese medicine composition for treating chronic ulcerative colitis | |
| CN101214365B (en) | Chinese medicine composing prescription for treating mastoproliferation | |
| CN102416121B (en) | Application of medicinal composition in preparation of medicaments for treating gastric ulcer | |
| CN101991794A (en) | Chinese traditional medicine preparation for treating eczema | |
| CN1290545C (en) | Medicine for curing coronary heart disease | |
| CN101564505B (en) | Chinese medicament for treating pulmonary heart disease | |
| CN100488539C (en) | Pharmaceutical composition for promoting blood circulation and preparation method thereof | |
| CN100542579C (en) | Yangxin Capsule for Treating Coronary Heart Disease | |
| CN102430073B (en) | Medicinal composition for treating peptic ulcer | |
| CN102416120B (en) | Application of medicinal composition in preparation of medicament for treating erosive gastritis | |
| CN103041233A (en) | Pharmaceutical composition for treating infantile diarrhea and preparation method thereof | |
| CN104547028A (en) | Traditional Chinese medicine composition capable of dredging blood vessels and removing plaques | |
| CN1244335C (en) | Influenze resisting medicine | |
| CN105362797A (en) | Traditional Chinese medicine for treating myocarditis | |
| CN102114174A (en) | Traditional Chinese medicine for treating acute cholecystitis | |
| CN1168482C (en) | Chinese medicine composition for treating enteritis | |
| CN102416122B (en) | Application of medicinal composition in preparation of medicaments for treating duodenal ulcer | |
| CN102397391A (en) | Medicine for treating hypertension, hyperlipemia and blood hyperviscosity and preparation method thereof | |
| CN102114211A (en) | Chinese herbal medicine for treating hepatopathy | |
| CN101167915B (en) | Traditional Chinese medicine for treating chronic superficial gastritis and its preparation method | |
| CN102210792A (en) | Traditional Chinese medicine for preventing and treating deep venous thrombosis | |
| CN1159028C (en) | Chinese medicine for treating various hemorrhagic diseases caused by reduced prothrombin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |