CN1693151A - Apparatus for drying preserving and recovering of liquid sample - Google Patents
Apparatus for drying preserving and recovering of liquid sample Download PDFInfo
- Publication number
- CN1693151A CN1693151A CN 200410038126 CN200410038126A CN1693151A CN 1693151 A CN1693151 A CN 1693151A CN 200410038126 CN200410038126 CN 200410038126 CN 200410038126 A CN200410038126 A CN 200410038126A CN 1693151 A CN1693151 A CN 1693151A
- Authority
- CN
- China
- Prior art keywords
- lid
- container body
- solid phase
- phase carrier
- egative film
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007788 liquid Substances 0.000 title claims abstract description 26
- 238000001035 drying Methods 0.000 title description 5
- 239000007790 solid phase Substances 0.000 claims description 47
- 239000012530 fluid Substances 0.000 claims description 28
- 239000011148 porous material Substances 0.000 claims description 12
- 239000011236 particulate material Substances 0.000 claims description 8
- 238000001179 sorption measurement Methods 0.000 claims description 4
- 239000007787 solid Substances 0.000 abstract description 9
- 239000000523 sample Substances 0.000 description 46
- 238000011084 recovery Methods 0.000 description 20
- 238000000034 method Methods 0.000 description 14
- 239000000463 material Substances 0.000 description 13
- 239000012472 biological sample Substances 0.000 description 6
- 239000007769 metal material Substances 0.000 description 5
- 238000004321 preservation Methods 0.000 description 5
- 230000004308 accommodation Effects 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
- 239000012528 membrane Substances 0.000 description 4
- -1 poly(lactic acid) Polymers 0.000 description 4
- 230000000274 adsorptive effect Effects 0.000 description 2
- 238000007605 air drying Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000007710 freezing Methods 0.000 description 2
- 230000008014 freezing Effects 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 229920000747 poly(lactic acid) Polymers 0.000 description 2
- 239000002861 polymer material Substances 0.000 description 2
- 230000008521 reorganization Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 1
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000008065 acid anhydrides Chemical class 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical class OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 239000004568 cement Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 238000005138 cryopreservation Methods 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000009795 derivation Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 150000004767 nitrides Chemical class 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920001610 polycaprolactone Polymers 0.000 description 1
- 239000004632 polycaprolactone Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000011819 refractory material Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 239000004576 sand Substances 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/405—Concentrating samples by adsorption or absorption
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5082—Test tubes per se
- B01L3/50825—Closing or opening means, corks, bungs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/042—Caps; Plugs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
- B01L2300/047—Additional chamber, reservoir
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/069—Absorbents; Gels to retain a fluid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
A device for storing the liquid specimen in dry mode and recovering it is composed of a container, a cover and a solid carrier attached to said cover. When said cover is matched with said container, said solid carrier can be fully contained in the container.
Description
Technical field
The present invention relates to a kind of device that is used for drying, preservation and the recovery of the kept dry of fluid sample and the device of recovery, particularly biological sample.
Background technology
Biological sample collection in the scientific research, preservation, transportation, reorganization, recovery are the condition precedenies that carries out various experimental science researchs, the various indexs detections of clinical medicine.Liquid biological sample is the biological sample form that the most extensively adopts in the life science, and to reclaim safety in its concentration accuracy of back and the biological sample processing overall process be one of biology, medical science, medicine, biological technical field basic problem that need solve for effective active (comprising in conjunction with activity and biologically active), integraty (as cell and other visible component), the sample reorganization of product content how to use the easiest cost-effective method to keep intact.For many years, scientific workers have made effort untiringly for this reason.
At present, the store method of fluid sample mainly is divided into liquid cryopreservation (2-8 degree Celsius); Freezing preservation (-20～-200 degree Celsius); Freezing (-60 degree Celsius are following) kept dry; (2-8 degree Celsius) preserved in low temperature drying; Preserve (10～30 degree or ambient temperatures Celsius) with air drying.
Utilized Schleicher ﹠amp first in 1963 from Robert Guthrie; (the S﹠amp of SchuellBioscience company; S company) 903 filter membranes (back claims Guthrie Card) are collected neonate's blood sample and have been carried out since the PKU examination, and this filter membrane has been widely used in the kept dry of biological fluid.Common sample recovery method is to have the filter membrane of fluid sample to take off kept dry with beam bear, is immersed in a period of time in the suitable buffer fluid, generally also needs heating to improve the percent recovery.When preserving fluid sample, the fluid sample in common multiple source is stored on the filter membrane, in recovery stage operation respectively again.Also be not used at present the device of fluid sample kept dry and recovery overall process.Though present air drying sample retention method has solved the kept dry and the transportation problem of fluid sample, also there are a lot of defectives aspect the sample liquids recovery.
Therefore, this area needs a kind of simple to operate, fluid sample kept dry that sample recovery rate is high, the device of recovery.
Summary of the invention
The invention provides a kind of particularly device of biological sample kept dry and recovery of fluid sample that is used for, it can make the kept dry of fluid sample become easy, and can be simply, recovery sample efficiently.
The present invention relates to a kind of device that is used for the kept dry of fluid sample, it comprises lid that can cooperate with container body and the solid phase carrier that is used for adsorption sample that is attached on this lid, and described solid phase carrier is contained in the chamber of container body fully when described lid cooperates with container body.
The invention still further relates to a kind of kept dry of fluid sample and device of recovery of being used for, it comprises lid and the solid phase carrier that is used for adsorption sample that is attached on this lid, with the container body that can cooperate with described lid, described solid phase carrier is contained in the chamber of container body fully when described lid cooperates with container body.
In a preferred embodiment, lid comprises egative film and with respect to the vertically disposed substantially periphery in egative film plane in apparatus of the present invention, and solid phase carrier is arranged in the space that egative film and periphery form.
In a preferred embodiment, in apparatus of the present invention lid comprise an egative film, with respect to the vertically disposed substantially periphery of this egative film with cover the top flat that has hole at described periphery top.Therefore, described lid forms the space of a relative closure, and solid phase carrier is positioned among this space.
In another embodiment, be connected with flexible connecting member between lid and the container body in the device of the present invention.
In an embodiment of apparatus of the present invention, described solid phase carrier is the particulate material of average pore size 0.01mm to the porous solid phase carrier of 5mm or mean grain size 0.01mm to 5mm.
In the present invention, the solid phase carrier that is used for the kept dry fluid sample is attached to lid, lid can with the container body driving fit.During use, be applied to fluid sample on the solid carrier and make its drying.After the drying, sample is preserved in lid and/or is transported.When recovery sample, the liquid that is used for reclaiming is installed in container body, then with lid and container body driving fit, makes the liquid contact and soaks the solid phase carrier that is adsorbed with dry sample, at last by gravity, manual vibration or centrifugally carry out Separation of Solid and Liquid, thereby finish the recovery of sample.Use that device of the present invention makes simply, recovery sample becomes possibility efficiently.
Description of drawings
Fig. 1 is the figure of first embodiment of the invention, and wherein 1 is the section-drawing of container body, and 2 is the section-drawing of lid, and 3 for being attached to the section-drawing of the solid phase carrier on the lid.
Fig. 2 is the figure of second embodiment of the invention, and wherein 1 is the section-drawing of container body, and 2 is the section-drawing of lid, and 3 for being attached to the section-drawing of the solid phase carrier on the lid.
Fig. 3 is the figure of third embodiment of the invention, and wherein 1 is the section-drawing of container body, and 2 is the section-drawing of lid, and 3 for being attached to the section-drawing of the solid phase carrier on the lid.
The specific embodiment
Shape and size to container body do not have particular determination.But container body is preferably cylindrical, more preferably is made of cylindrical and taper two parts, and wherein the container body opening part is a cylindrical part, is taper near the part bottom the container body, and the container body bottom is the minimum place of the diameter of tapering part.Container body in apparatus of the present invention is preferably the container of operations such as being commonly used to carry out fluid sample is deposited, reacted, separation in this area, for example various test tubes, centrifuge tube etc.More preferably the container body among the present invention is a kind of centrifuge tube, for example the Eppendorf pipe.
Shape to lid does not have particular determination, but should adapt with the shape of container body.For example, when the container body opening part was circle, lid was circular.Described lid can be the platysome that simply can cooperate with container body.Under this situation, solid carrier preferably has solid shape, and is fixed on the lid by bonding or physical connection.
In a preferred embodiment, the lid of apparatus of the present invention has an egative film and is basically perpendicular to the periphery that covers the setting of egative film plane.Described egative film and periphery constitute the small container of (when lid cooperates with a container body) opening in container.Solid-support immobilized is in this small container.The height of periphery can be provided with according to the volume of solid phase carrier.In addition, described periphery also can be simultaneously as the parts that cooperate with container body.
In a preferred embodiment, the lid of apparatus of the present invention is made of an egative film, the top flat that is basically perpendicular to the periphery of described egative film setting and covers described periphery top.Like this, lid forms the space of a relative closure.Solid phase carrier places among this space, can with lid part between without any being connected or being fixed on the lid by any way.In this case, when lid cooperated with container body, top flat was towards container body inside.Described top flat needs hole, and for example aperture or slit are so that fluid sample contacts with reclaiming can enter in the lid with wherein solid carrier with liquid.For example described top flat is a net structure.The size of described hole is suitable for solid carrier is retained in the lid.In this embodiment, periphery also can be used for and the cooperating of container body.
Fit system to container body and lid does not have particular determination, as long as this cooperation is fluid-tight.Container body and lid can be separate members, but preferably can link together by a flexible connecting member.For example, in the sample removal process, link together at least, to make things convenient for reclaimer operation by attaching parts spare container body and lid.
Container body of the present invention and lid can be made by any material impervious to water, particularly are suitable for handling the material of living sample.For example, can use various plastics, glass etc.
Volume to solid phase carrier does not have particular determination, but preferably it is no more than the container body volume half, more preferably no more than 1/3rd of container body volume, so that used liquid stays enough action spaces when reclaiming for sample.Material to solid phase carrier does not have particular restriction, as long as it can adsorb and the kept dry fluid sample.For example described solid phase carrier can be the conventional filter paper that uses, and is 0.01mm to the particulate material of 5mm (see Chinese patent application that the applicant submits to number 200410004387.4,200410029523.5) but to be preferably average pore size be 0.01mm to the porous solid phase carrier of 5mm or mean grain size.
Average pore size is 0.01mm to porous solid phase carrier and the mean grain size of 5mm is that 0.01mm can make by any material to the particulate material of 5mm, for example is selected from down one or more materials of group: polymeric material, the material through chemical treatment or untreated biogenetic derivation, metallic material and Inorganic Non-metallic Materials.In a preferred embodiment, the used cellular solid of the present invention is a polymeric material.In another preferred embodiment, the used particulate material of the present invention is an Inorganic Non-metallic Materials.The example of polymeric material has: hydroxycarboxylic acid esters, as poly-(3-butyric ester) (PHB), 3-butyric ester and 3-hydroxycaproic acid ester copolymer (PHB-HH), poly(lactic acid) (PLA), poly lactic coglycolic acid (PLGA), polycaprolactone; Poe, poly-acid anhydrides etc.Described porous polymer material can obtain easily by art methods, for example by methods such as polymer foamings.The aperture of described porous polymer material also can be controlled according to a conventional method, thereby obtains to be suitable for the concrete aerated materials of using.Inorganic Non-metallic Materials comprises pottery, glass, cement, refractory material, various ore, sand grains etc.These materials can be made particulate material by the conventional approach of this area.The chemical composition of Inorganic Non-metallic Materials comprises silicate, other oxysalt, oxide, nitride, carbon and carbide metal, boride, fluoride, chalcogenide compound, silicon, germanium, II-V and II-VI compounds of group etc.
The device that liquid dried is as shown in Figure 1 preserved and reclaimed.It is made of container body 1, lid 2 and solid phase carrier 3.
The device that liquid dried is as shown in Figure 2 preserved and reclaimed, it is made of container body 1, lid 2 and solid phase carrier 3.
Except that above-mentioned fit system, hold body 2a and supporting base 2b and can engage in many ways and realize that the close property of liquid cooperates for example integrally formed or other various correlation techniques well known in the art.For example, supporting base 2b has annular groove towards the one side of container body, and its width equates with the wall thickness that holds body 2a, and diameter and the equal diameters of holding body 2a make that holding body 2a realizes that by embedded mode the close property of liquid cooperates with supporting base 2b.Have the pore configuration except holding body bottom 2a-2, hold body top 2a-1 and also can have pore configuration.
Material to solid phase carrier 3 does not have particular restriction, as long as it can adsorptive liquid sample and kept dry fluid sample, being preferably average pore size and being 0.01mm is the particulate material of 0.01mm to 5mm to porous solid phase carrier or the mean grain size of 5mm.Shape, volume to solid phase carrier 3 do not have particular determination, as long as it can be contained in fully and hold among the body 2a, but preferred solid phase carrier 3 is full of and holds body 2a, makes fluid sample fully to be absorbed.
The device that liquid dried is as shown in Figure 3 preserved and reclaimed, it is made of container body 1, lid 2 and solid phase carrier 3.
Except that above-mentioned fit system, pressing plate 2e can engage in many ways with carrier ring 2b and realize that the close property of liquid cooperates for example integrally formed or other various correlation techniques well known in the art.For example, pressing plate 2e can realize that the close property of liquid cooperates by the spiral fit system with carrier ring 2b.Remove integrally formedly, hold body top 2a-1 and hold body bottom 2a-2 can engage in many ways to form and hold body 2a, for example screw thread fit.Have the pore configuration except holding body bottom 2a-2, hold body top 2a-1 and also can have pore configuration.
The material of solid phase carrier 3 does not have particular restriction, as long as it can adsorptive liquid sample and kept dry fluid sample, being preferably average pore size and being 0.01mm is the particulate material of 0.01mm to 5mm to porous solid phase carrier or the mean grain size of 5mm.Shape, volume to solid phase carrier 3 do not have particular determination, as long as it can be contained in fully and hold among the body 2a, but preferred solid phase carrier 3 is full of the spatial accommodation that holds body 2a and pressing plate 2e formation, makes fluid sample fully to be absorbed.
Claims (9)
1. device that is used for the kept dry of fluid sample, it comprises lid that can cooperate with container body and the solid phase carrier that is used for adsorption sample that is attached on this lid, and described solid phase carrier is contained in the chamber of container body fully when described lid cooperates with container body.
2. according to the device of claim 1, wherein said lid is platysome substantially.
3. according to the device of claim 1, wherein said lid comprises an egative film and is basically perpendicular to the periphery of the plane setting of described egative film, in the space that solid phase carrier forms between described egative film and periphery.
4. according to the device of claim 1, wherein said lid comprises an egative film, be basically perpendicular to periphery that the plane of described egative film is provided with and the top flat that has hole that covers described periphery top, and solid phase carrier is arranged in the space of described egative film, periphery and the formed relative closure of top flat.
5. according to the device of claim 3 or 4, wherein said egative film and periphery are integrally formed or by screw thread fit or concavo-convex chimeric being combined into one.
6. according to the device of claim 1, wherein can the close property of liquid cooperate between lid and the container body.
7. according to the device of claim 1, wherein be connected with flexible connecting member between lid and the container body.
8. according to the device of claim 1, wherein said solid phase carrier is the particulate material of average pore size 0.01mm to the porous solid phase carrier of 5mm or mean grain size 0.01mm to 5mm.
9. one kind is used for the kept dry of fluid sample and the device that reclaims, it comprises lid and the solid phase carrier that is used for adsorption sample that is attached on this lid, with the container body that can cooperate with described lid, described solid phase carrier is contained in the chamber of container body fully when described lid cooperates with container body.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410038126 CN1693151A (en) | 2004-05-08 | 2004-05-08 | Apparatus for drying preserving and recovering of liquid sample |
| PCT/CN2005/000285 WO2005108950A1 (en) | 2004-05-08 | 2005-03-09 | A device for drying, preserving and recovering liquid samples |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410038126 CN1693151A (en) | 2004-05-08 | 2004-05-08 | Apparatus for drying preserving and recovering of liquid sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1693151A true CN1693151A (en) | 2005-11-09 |
Family
ID=35320321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410038126 Pending CN1693151A (en) | 2004-05-08 | 2004-05-08 | Apparatus for drying preserving and recovering of liquid sample |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN1693151A (en) |
| WO (1) | WO2005108950A1 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106103686A (en) * | 2013-12-04 | 2016-11-09 | 杭州金源生物技术有限公司 | There is the sample cell assembly that improved leakage is taken precautions against |
| CN108579832A (en) * | 2018-05-21 | 2018-09-28 | 淮阴师范学院 | A kind of chemical experiment liquid storage bottle |
| CN119756979A (en) * | 2024-12-18 | 2025-04-04 | 浙江清华长三角研究院 | A system, method and application for preserving human body fluids and excrement |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8535945B2 (en) | 2008-12-19 | 2013-09-17 | 3M Innovative Properties Company | System and method for concentrating samples |
| CN102317754B (en) | 2008-12-19 | 2015-09-30 | 3M创新有限公司 | Systems and methods for processing samples |
| EP2484448A1 (en) * | 2011-02-03 | 2012-08-08 | Universite De Geneve | Non-card format devices for collecting, storing & analysing dried body fluid spots and related methods |
| JP2014526041A (en) | 2011-06-30 | 2014-10-02 | スリーエム イノベイティブ プロパティズ カンパニー | System and method for detecting an analyte of interest in a sample using a filter and a microstructured surface |
| JP2014518394A (en) | 2011-06-30 | 2014-07-28 | スリーエム イノベイティブ プロパティズ カンパニー | System and method for detecting a target analyte in a sample using a microstructured surface |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6265223B1 (en) * | 1997-05-28 | 2001-07-24 | Flexsite Diagnostics, Inc. | Diagnostic assay |
| US6032474A (en) * | 1998-05-29 | 2000-03-07 | Forensic Solutions, Inc. | Evidence preservation system |
| BR0206488A (en) * | 2001-11-15 | 2008-08-05 | Whatman Inc | device, method and kit for storing and analyzing a portion containing nucleic acid in a biological sample |
-
2004
- 2004-05-08 CN CN 200410038126 patent/CN1693151A/en active Pending
-
2005
- 2005-03-09 WO PCT/CN2005/000285 patent/WO2005108950A1/en not_active Ceased
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106103686A (en) * | 2013-12-04 | 2016-11-09 | 杭州金源生物技术有限公司 | There is the sample cell assembly that improved leakage is taken precautions against |
| CN108579832A (en) * | 2018-05-21 | 2018-09-28 | 淮阴师范学院 | A kind of chemical experiment liquid storage bottle |
| CN119756979A (en) * | 2024-12-18 | 2025-04-04 | 浙江清华长三角研究院 | A system, method and application for preserving human body fluids and excrement |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005108950A1 (en) | 2005-11-17 |
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