CN1517115A - Chinese patent drug-Fuyan capsdule for treating chronic pelvic inflammation - Google Patents
Chinese patent drug-Fuyan capsdule for treating chronic pelvic inflammation Download PDFInfo
- Publication number
- CN1517115A CN1517115A CNA031117473A CN03111747A CN1517115A CN 1517115 A CN1517115 A CN 1517115A CN A031117473 A CNA031117473 A CN A031117473A CN 03111747 A CN03111747 A CN 03111747A CN 1517115 A CN1517115 A CN 1517115A
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- CN
- China
- Prior art keywords
- chronic pelvic
- chinese patent
- woman
- fuyan
- inflammation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 208000029082 Pelvic Inflammatory Disease Diseases 0.000 title claims abstract description 19
- 230000001684 chronic effect Effects 0.000 title claims abstract description 15
- 239000003814 drug Substances 0.000 claims abstract description 23
- 239000002775 capsule Substances 0.000 claims abstract description 11
- 241000628997 Flos Species 0.000 claims description 5
- 210000000582 semen Anatomy 0.000 claims description 5
- 239000012567 medical material Substances 0.000 claims description 4
- 239000000796 flavoring agent Substances 0.000 claims description 3
- 235000019634 flavors Nutrition 0.000 claims description 3
- 239000002994 raw material Substances 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 7
- 229940079593 drug Drugs 0.000 abstract description 6
- 208000004145 Endometritis Diseases 0.000 abstract description 3
- 206010049677 Salpingo-oophoritis Diseases 0.000 abstract description 3
- 239000000706 filtrate Substances 0.000 abstract description 3
- 238000001914 filtration Methods 0.000 abstract description 3
- 244000144730 Amygdalus persica Species 0.000 abstract 1
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 206010057254 Connective tissue inflammation Diseases 0.000 abstract 1
- 244000170916 Paeonia officinalis Species 0.000 abstract 1
- 235000006484 Paeonia officinalis Nutrition 0.000 abstract 1
- 235000006040 Prunus persica var persica Nutrition 0.000 abstract 1
- 240000007164 Salvia officinalis Species 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000010298 pulverizing process Methods 0.000 abstract 1
- 235000005412 red sage Nutrition 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 description 11
- 230000004054 inflammatory process Effects 0.000 description 11
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 210000002808 connective tissue Anatomy 0.000 description 4
- 230000003203 everyday effect Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 231100000915 pathological change Toxicity 0.000 description 2
- 230000036285 pathological change Effects 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 206010003694 Atrophy Diseases 0.000 description 1
- 241001269238 Data Species 0.000 description 1
- 241000792859 Enema Species 0.000 description 1
- 206010016654 Fibrosis Diseases 0.000 description 1
- 206010020880 Hypertrophy Diseases 0.000 description 1
- 208000019255 Menstrual disease Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000007059 acute toxicity Effects 0.000 description 1
- 231100000403 acute toxicity Toxicity 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000004856 capillary permeability Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 239000007920 enema Substances 0.000 description 1
- 229940095399 enema Drugs 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000004761 fibrosis Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 208000021267 infertility disease Diseases 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- RSMUVYRMZCOLBH-UHFFFAOYSA-N metsulfuron methyl Chemical compound COC(=O)C1=CC=CC=C1S(=O)(=O)NC(=O)NC1=NC(C)=NC(OC)=N1 RSMUVYRMZCOLBH-UHFFFAOYSA-N 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 238000000554 physical therapy Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 230000002062 proliferating effect Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 210000004999 sex organ Anatomy 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
A Chinese patent drug 'Fuyan capsule' for treating chronic pelvic inflammation, endometritis, adnexitis and connective tissue inflammation is prepared from 13 Chinese-medicinal materials including honeysuckle flower, red peony root, peach kernel, red sage root, etc through decocting for 2 hr, filtering, decocting the dregs twice, collecting filtrate, concentrating, baking, pulverizing, and filling in capsules. Its advantages are high curative effect and less sequelae.
Description
One, technical field
The present invention relates to a kind of pharmaceutical composition for the treatment of chronic pelvic inflammatory disease, particularly relating to a kind of is the scorching capsule of Chinese patent medicine one woman of the treatment chronic pelvic inflammatory disease made of raw material with the vegetable Chinese herbal medicine.
Two, background technology
Chronic pelvic inflammatory disease comprises endometritis, adnexitis and inflammation of pelvic connective tissue, is that the woman expects commonly encountered diseases, frequently-occurring disease, also is one of difficult and complicated illness, and a tree name statistics accounts for more than 60% of adult women.Because acute pelvic inflammatory disease treatment is untimely, not thorough, or patient's body constitution is relatively poor, or the get the brush-off delay or develop of light-duty subacute pathological changes forms.Modern medicine is thought, because patient's premorbid existence self metaboilic level is low, resistance against diseases obviously goes down, when meeting aerobe or anaerobic infection, make inflammation to palace body, the other diffusion in palace, and then cause the inflammation of adnexa and pelvic cavity connective tissue, certainly exist local patholoic change and produce pathological changes such as adhesion, atrophy, fibrosis.Aspect treatment, doctor trained in Western medicine adopts antibiosis to have certain effect, but prolonged application not only directly reduces the infection curative effect, also can cause bacterial resistance, untoward reaction also can occur and add heavy patient's financial burden.
Primary disease is under the jurisdiction of motherland's medical science " leukorrheal diseases ", " stomachache ", “ mass in the abdomen ", " menoxenia " and categories such as " infertile ".It is generally acknowledged how to fall ill owing to damp and hot heresy injures conception vessel, " element is asked the bone empty talk " just once pointed out: " conception vessel is for sick, and woman's leukorrhagia gathers ".Ancient Chinese medicine doctor is not interrupted research to this disease always, the tradition prescription has that yihuang decoction, Erhuang three are white to loose etc., recently the usefulness that has of scholar is from intending prescription (comprising decoction, Chinese patent medicine), what also have treats with methods such as Chinese traditional medicine wet compress, herbal enema, physical therapys, these method curative effects are all not really definite, recurrence easily, and what have is also cumbersome, patient is difficult to adhere to use, can not be widely at clinical application.
Three, summary of the invention
Purpose of the present invention can overcome above-mentioned deficiency exactly, and a kind of good effect be provided, be difficult for recur, have no side effect, cheap, the Chinese patent medicine one woman inflammation capsule of being convenient to the treatment chronic pelvic inflammatory disease of using and carrying.
The technical scheme that the present invention takes is basis modal " damp and hot blood stasis " card clinically, adopts clearing away heat and eliminating dampness, activating blood and resolving stasis and treating, is that the medicine card conforms to the bone joints-most important juncture of hitting.The modern Chinese medicine pharmacological research proves that clearing away heat and eliminating dampness class medicine can reduce capillary permeability, and minimizing is oozed out, and the acceleration inflammation absorbs, the further hypertrophy of prevention connective tissue, and drug for invigorating blood circulation and eliminating stasis can change blood flow, promotes the softening and absorption of proliferative lesion.
The scorching capsular medicine of the Chinese patent medicine woman of treatment chronic pelvic inflammatory disease is formed: used medical material part by weight is Flos Lonicerae 15～18g, Fructus Forsythiae 12～15g, Rhizoma Smilacis Glabrae 15～30g, Cortex Phellodendri 12～15g, Herba Patriniae 15～30g, Caulis Sargentodoxae 12～15g, Herba Hedyotidis Diffusae 15～30g, Cortex Ailanthi 15～30g, Bi 15～30g, Radix Paeoniae Rubra 12～15g, Semen Persicae 12～15g, Rhizoma Curcumae 10～12g, Radix Salviae Miltiorrhizae 12～30g.
Scorching capsular optimum weight (gram) proportioning of woman of the present invention is: Flos Lonicerae 15g, Fructus Forsythiae 12g, Rhizoma Smilacis Glabrae 15 g, Cortex Phellodendri 12g, Herba Patriniae 15g, Caulis Sargentodoxae 12g, Herba Hedyotidis Diffusae 15g, Cortex Ailanthi 15g, Bi 15g, Radix Paeoniae Rubra 12g, Semen Persicae 12g, Rhizoma Curcumae 10g, Radix Salviae Miltiorrhizae 12g.
Above-mentioned each component is made the scorching capsular preparation method of woman of the present invention is: get above 13 flavor medicines and add water to submerge decoction 2 hours, filter, filtering residue repeats to decoct 2 times, and merging filtrate is condensed into thick paste, and oven dry is ground into fine powder and incapsulates standby.
Specification: 0.4g * 60/bottle.
Usage and dosage: each 6～8, every day 3 times, ante cibum is oral or follow the doctor's advice.
Four, beneficial effect
The present invention has inflammation-inhibiting preferably and the effect of the sequela that reduces inflammation, and in the process of treatment chronic pelvic inflammatory disease, good therapeutic effect is arranged.Cure mainly the female sex organ inflammation, be mainly used in chronic pelvic inflammatory disease, endometritis, adnexitis and inflammation of connective tissue etc.
See Appendix 1 (experiment and the clinical research technical report of the scorching capsule for treating chronic pelvic inflammatory disease of woman)
See Appendix 2 (the scorching capsule for treating chronic pelvic inflammatory disease of woman testing datas)
Five, embodiment
The scorching capsule of woman of the present invention takes by weighing raw material (kilogram) by following proportioning, and the amount of getting of various medical materials is: Flos Lonicerae 15g, Fructus Forsythiae 12g, Rhizoma Smilacis Glabrae 15g, Cortex Phellodendri 12g, Herba Patriniae 15g, Caulis Sargentodoxae 12g, Herba Hedyotidis Diffusae 15g, Cortex Ailanthi 15g, Bi 15g, Radix Paeoniae Rubra 12g, Semen Persicae 12g, Rhizoma Curcumae 10g, Radix Salviae Miltiorrhizae 12g.Preparation method is: get above 13 flavor medicines and add water to submerge decoction 2 hours, filter, filtering residue repeats to decoct 2 times, and merging filtrate is condensed into thick paste, and oven dry is ground into fine powder and incapsulates standby.Be assigned randomly to treatment group (A) or matched group (B) by screening qualified case, the treatment group is totally 100 examples, and matched group is totally 50 examples.The treatment group is taken the scorching capsule of woman, every day 3 times, each 6～8; Matched group is taken FULE CHONGJI, every day 2 times, each 9g.It is the course of treatment that two medicines are all obeyed one month, and carries out the inspection of health giving quality and safety detection before and after taking medicine, through clinical observation, treatment group total effective rate is 93.75%, and the matched group total effective rate is 75.84%, and the treatment group is apparently higher than matched group, confirmed this medication effect significantly, had no adverse reaction.The present invention of experimental result proof has inflammation-inhibiting, the sequela that reduces inflammation and obviously analgesic effect preferably, and animal acute toxicity experiment is observed oral safety.Evident in efficacy, have no side effect; Practical, cheap, the medicine source is wide, and it is easy to carry to take safety, for the treatment of chronic pelvic inflammatory disease provides a new approach.
Claims (2)
1, a kind of scorching capsule of Chinese patent medicine one woman for the treatment of chronic pelvic inflammatory disease, it is characterized in that being made up of 13 flavor medical materials, its used medical material part by weight is Flos Lonicerae 15～18g, Fructus Forsythiae 12～15g, Rhizoma Smilacis Glabrae 15～30g, Cortex Phellodendri 12～15g, Herba Patriniae 15～30g, Caulis Sargentodoxae 12～15g, Herba Hedyotidis Diffusae 15～30g, Cortex Ailanthi 15～30g, Bi 15～30g, Radix Paeoniae Rubra 12～15g, Semen Persicae 12～15g, Rhizoma Curcumae 10～12g, Radix Salviae Miltiorrhizae 12～30g.
2, the scorching capsule of Chinese patent medicine one woman of treatment chronic pelvic inflammatory disease according to claim 1, wherein the weight proportion of each raw material is Flos Lonicerae 15g, Fructus Forsythiae 12g, Rhizoma Smilacis Glabrae 15g, Cortex Phellodendri 12g, Herba Patriniae 15g, Caulis Sargentodoxae 12g, Herba Hedyotidis Diffusae 15g, Cortex Ailanthi 15g, Bi 15g, Radix Paeoniae Rubra 12g, Semen Persicae 12g, Rhizoma Curcumae 10g, Radix Salviae Miltiorrhizae 12g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03111747 CN1246031C (en) | 2003-01-18 | 2003-01-18 | Chinese patent drug-Fuyan capsdule for treating chronic pelvic inflammation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03111747 CN1246031C (en) | 2003-01-18 | 2003-01-18 | Chinese patent drug-Fuyan capsdule for treating chronic pelvic inflammation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1517115A true CN1517115A (en) | 2004-08-04 |
| CN1246031C CN1246031C (en) | 2006-03-22 |
Family
ID=34283493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 03111747 Expired - Fee Related CN1246031C (en) | 2003-01-18 | 2003-01-18 | Chinese patent drug-Fuyan capsdule for treating chronic pelvic inflammation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1246031C (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1316991C (en) * | 2004-12-21 | 2007-05-23 | 中国农业科学院兰州畜牧与兽药研究所 | A kind of traditional Chinese medicine for treating bovine endometritis |
| RU2304966C1 (en) * | 2005-12-26 | 2007-08-27 | ГУ Научно-исследовательский институт клинической и экспериментальной лимфологии СО РАМН | Method for treating and preventing the relapses of uterine and adnexal inflammation in women of reproductive age |
| CN101181599B (en) * | 2007-11-20 | 2010-06-23 | 浙江大学 | A kind of Chinese medicine composition and application for treating chronic pelvic inflammatory disease |
| CN102302746A (en) * | 2011-09-20 | 2012-01-04 | 浙江大学 | Traditional Chinese medicine composition for treating pelvic inflammatory disease (PID) and application thereof |
| CN103099909A (en) * | 2013-01-25 | 2013-05-15 | 大连民族学院 | Retention enema for treating chronic pelvic inflammation |
| CN104367946A (en) * | 2014-11-06 | 2015-02-25 | 青岛恒波仪器有限公司 | Traditional Chinese medicine suppository for treating chronic endometritis and preparation method thereof |
| CN105596510A (en) * | 2016-01-15 | 2016-05-25 | 张帆 | Chinese patent medicine for treating miscellaneous gynecological diseases |
| CN106266258A (en) * | 2016-09-21 | 2017-01-04 | 张帆 | A kind of Chinese patent medicine for treating miscellaneous gynecological diseases |
-
2003
- 2003-01-18 CN CN 03111747 patent/CN1246031C/en not_active Expired - Fee Related
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1316991C (en) * | 2004-12-21 | 2007-05-23 | 中国农业科学院兰州畜牧与兽药研究所 | A kind of traditional Chinese medicine for treating bovine endometritis |
| RU2304966C1 (en) * | 2005-12-26 | 2007-08-27 | ГУ Научно-исследовательский институт клинической и экспериментальной лимфологии СО РАМН | Method for treating and preventing the relapses of uterine and adnexal inflammation in women of reproductive age |
| CN101181599B (en) * | 2007-11-20 | 2010-06-23 | 浙江大学 | A kind of Chinese medicine composition and application for treating chronic pelvic inflammatory disease |
| CN102302746A (en) * | 2011-09-20 | 2012-01-04 | 浙江大学 | Traditional Chinese medicine composition for treating pelvic inflammatory disease (PID) and application thereof |
| CN103099909A (en) * | 2013-01-25 | 2013-05-15 | 大连民族学院 | Retention enema for treating chronic pelvic inflammation |
| CN104367946A (en) * | 2014-11-06 | 2015-02-25 | 青岛恒波仪器有限公司 | Traditional Chinese medicine suppository for treating chronic endometritis and preparation method thereof |
| CN105596510A (en) * | 2016-01-15 | 2016-05-25 | 张帆 | Chinese patent medicine for treating miscellaneous gynecological diseases |
| CN106266258A (en) * | 2016-09-21 | 2017-01-04 | 张帆 | A kind of Chinese patent medicine for treating miscellaneous gynecological diseases |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1246031C (en) | 2006-03-22 |
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