CN1562201A - 治疗骨折的中药制剂及其它的制备方法 - Google Patents
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Abstract
本发明是一种治疗骨折的中药制剂及其它的制备方法，它由儿茶、红花、血竭、等十多味药材制备而成，具有接骨续筋、消肿止痛的功能，用于对各种骨折伤痛及扭伤的治疗，它的特点是：对外伤性疼痛具消肿止痛，舒经活络的功效，能促使骨折部位消肿止痛，改善局部血液循环，防止感染，促使骨质生长，缩短骨折愈合时间，其疗效显著。
Description
技术领域：本发明是一种治疗骨折的中药制剂及其它的制备方法，属于中药技术的领域。
技术背景：骨折、脱位，关节扭伤，骨质增生，风湿性关节炎及软组织损伤，是临床常见病症；该症的治疗，目前方法较多，药物各异：外用喷雾剂、口服跌打剂等治疗跌打损伤临床应用较为广泛，是骨伤科止痛、散瘀、消肿的常用剂型，虽均能够达一定疗效，但仍存在如何进一步提高疗效以及减少副作用等问题；因此，研究和探讨新的临床治疗药物，在现阶段仍具有重要意义。
发明内容：本发明的目的在于：针对本申请人祖传验方进行细致的研究、来提供一种接骨续筋、消肿止痛，用于各种骨折伤痛及扭伤的治疗骨折的中药制剂及其它的制备方法。本发明是这样构成的：治疗骨折的中药制剂，按照重量组份计算：它由儿茶300-400、红花300-400、血竭50-90、赤芍600-800、当归300-400、丹皮150-200、川芎150-200、香附150-200、乳香40-45、没药40-45、乌药150-200、茯苓300-400、甘草45-60、朱砂4-10、琥珀10-20、木香40-45、丁香40-45制备而成。准确地说：按照重量组份计算：它由儿茶350g、红花350g、血竭70g、赤芍700g、当归350g、丹皮175g、川芎175g、香附175g、乳香43.75g、没药43.75g、乌药175g、茯苓350g、甘草52.5g、朱砂7g、琥珀14g、木香43.7g、丁香43.75g制备而成。本发明所述的制剂为所有医学允许的口服制剂，包括：片、颗粒、胶囊、软胶囊、口服液、丸、散。所述的治疗骨折的中药制剂的制备方法是：称量这17味药材，除血竭、朱砂、琥珀外将赤芍、当归、红花等其余药材用水洗净，水洗过的药材干燥，干燥后的药材进行粉碎、过筛得细粉，血竭单独粉碎备用，粉碎后的群药与血竭、琥珀、朱砂混匀得本药物，然后根据需求制备成需要的剂型，可以直接压制成片剂、装入胶囊中制成胶囊剂或者加入适量的蔗糖、制备成颗粒剂或口服液制剂。本发明制备丸剂的方法是：称取17味药材、除血竭、
朱砂、琥珀外，将赤芍、当归、红花、等群药用水洗净，水洗过的药物入干燥箱干燥，干燥箱温度控制在50℃——60℃之间，干燥后的药物入粉碎机粉碎、过五号筛使之呈细粉，血竭单独乳体粉碎备用，粉碎后的群药与血竭、琥珀、朱砂混匀，将适量蜂蜜在容器内根据标准加热炼制、过筛备用，将粉碎好的药粉和蜜以1∶1的比例入合坨机、合成药坨，合成后的药坨入蜜丸机制成每丸重6g的蜜丸。
与现有技术相比：本发明本发明具有接骨续筋、消肿止痛的功能，用于各种骨折伤痛及扭伤，它的特点是：对外伤性疼痛具消肿止痛，舒经活络的功效，能促使骨折部位消肿止痛，改善局部血液循环，防止感染，促使骨质生长，缩短骨折愈合时间，其疗效显著，同时，对部份病员治疗前后肝、肾功能等观察中未见毒副作用。
本发明中的君药：儿茶、红花、血竭、赤芍、当归、丹皮、川芎；
儿茶：清热、化痰，止血、消食，生肌、定痛：
红花：具有活血通经，去瘀止痛。治经闭，难产，死胎，产后恶露行，瘀血作痛，痈肿，跌扑损伤。
血竭：具有散瘀定痛，止血生肌，治跌打折损，内伤瘀痛，外伤出血不止，瘰疬，臁疮溃久不合。
当归：具有补血和血，调经止痛，润燥滑肠。治月经不调，经闭腹痛，崩漏；血虚头痛，眩晕，痿痹；肠燥便难，赤痢后理，痈疽疮疡，跌打损伤。
赤芍：行瘀，止痛，凉血，消肿。治瘀滞经闭，疝瘕积聚，腹痛，胁痛，衄血，血痢，肠风下血，目赤，痈肿。
丹皮：清热，凉血，和血，消瘀，治热入血分，发斑，吐，衄，便血，骨蒸劳热，经闭，痈疡，扑损。
川芎：行气开郁，祛风燥湿，活血止痛，治风冷头痛旋晕，胁痛腹疼，寒痹筋挛，经闭，难产，产后瘀阻块痛，痈疽疮疡。
臣药：香附、乳香、没药、乌药、茯苓、木香、丁香；
香附：理气解郁，止痛调经，治肝胃不和，气郁不舒，胸腹胁肋胀痛，痰饮痞满，月经不调，崩漏带下。
乳香：调气活血，定痛，追毒。治气血凝滞，心腹疼痛。痈疮肿毒，跌打损伤，痛经，产后瘀血刺痛。
没药：散血去瘀，消肿定痛，治跌损，金疮，筋骨，心腹诸痛，经闭，痈疽肿痛，痔漏，目障。
乌药：顺气，开郁，散寒，止痛。治气逆胸腹胀痛，宿食不消，反胃吐食，寒疝，脚气，小便频数。
茯苓：渗湿利水，益脾和胃，宁心安神。治小便不利，水肿胀满，痰饮咳逆，呕哕，泄泻，遗精，淋浊，惊悸，健忘。
木香：行气止痛，温中和胃，治中寒气滞，胸腹胀痛，呕吐，泄泻，下痢里急后重，寒疝。
丁香：温中，暖肾，降逆，治呃逆，呕吐，反胃，泻痢，心腹冷痛，痃癖，疝气，癣疾。
佐药：朱砂、琥珀；
朱砂：安神，定惊，明目，解毒。治癫狂，惊悸，心烦，失眠，眩晕，目昏，肿毒，疮疡，疥癣。
琥珀：益气，明目，强筋骨，治虚损，呃逆。
使药：甘草：和中缓急，润肺，解毒，调和诸药，炙用，治脾胃虚弱，食少，腹痛便溏，劳倦发热，肺痿咳嗽，心悸，生用，治咽喉肿痛，消化性溃疡，痈疽疮疡，解药毒及食物中毒。
从方解看：本发明合理利用各味中药的综合治疗原则，吸取现代药理研究成果，从祖国医药宝库中，筛选出和血、止血、散瘀定痛、接骨续筋，镇静，消肿，生肌的中药，按中医理论科学配伍，具有接骨坚、愈合快、疗程短、制作简单，服用方便，无副作用的特点。
正常新骨折患者，包括粉碎性骨折，经手法或手术复位固定后，用本发明的药物只需十余天，再休息十天可慢慢活动，月内即可痊愈；对骨折后久不愈合的患者，用药二十到三十天，慢慢活动一到二个月即可痊愈；经临床100例骨折患者治疗，有效率100％，治愈率100％。本发明药物作为治疗外伤性骨折、脱位、关节扭伤、骨质增生、风湿性关节炎、及软组织损伤的一种中药外用制剂，其疗效满意，使用方便，安全，为临床验证的治疗，提供了新的选择。
具体实施方式：
本发明的实施例1：它由儿茶350g、红花350g、血竭70g、赤芍700g、当归350g、丹皮175g、川芎175g、香附175g、乳香43.75g、没药43.75g、乌药175g、茯苓350g、甘草52.5g、朱砂7g、琥珀14g、木香43.75g、丁香43.75g制备而成。制备丸剂的方法是：称取17味药材、除血竭、朱砂、琥珀外，将赤芍、当归、红花、等群药用水洗净，水洗过的药物入干燥箱干燥，干燥箱温度控制在50℃——60℃之间，干燥后的药物入粉碎机粉碎、过五号筛使之呈细粉，血竭单独乳体粉碎备用，粉碎后的群药与血竭、琥珀、朱砂混匀，将适量蜂蜜在容器内根据标准加热炼制、过筛备用，将粉碎好的药粉和蜜以1∶1的比例入合坨机、合成药坨，合成后的药坨入蜜丸机制成每丸重6g的蜜丸。本丸的商品名称为“健止丸”；口服一日二次、每次1丸。
本发明的实施例2：它由儿茶300g、红花300g、血竭50g、赤芍600g、当归300g、丹皮150g、川芎150g、香附150g、乳香40g、没药40g、乌药150g、茯苓300g、甘草45g、朱砂4g、琥珀10g、木香40g、丁香40g制备而成。制备方法是：称量这17味药材，除血竭、朱砂、琥珀外将赤芍、当归、红花等其余药材用水洗净，水洗过的药材干燥，干燥后的药材进行粉碎、过筛得细粉，血竭单独粉碎备用，粉碎后的群药与血竭、琥珀、朱砂混匀得本药物，然后压制成片剂。
本发明的实施例3：它由儿茶400g、红花400g、血竭90g、赤芍800g、当归400g、丹皮200g、川芎200g、香附200g、乳香45g、没药45g、乌药200g、茯苓400g、甘草60g、朱砂10g、琥珀20g、木香45g、丁香45g制备而成。制备方法是：称量这17味药材，除血竭、朱砂、琥珀外将赤芍、当归、红花等其余药材用水洗净，水洗过的药材干燥，干燥后的药材进行粉碎、过筛得细粉，血竭单独粉碎备用，粉碎后的群药与血竭、琥珀、朱砂混匀得本药物，然后加入适量的蔗糖、制备成颗粒剂。
Claims (5)
1、一种治疗骨折的中药制剂，其特征在于：按照重量组份计算：它由儿茶300-400、红花300-400、血竭50-90、赤芍600-800、当归300-400、丹皮150-200、川芎150-200、香附150-200、乳香40-45、没药40-45、乌药150-200、茯苓300-400、甘草45-60、朱砂4-10、琥珀10-20、木香40-45、丁香40-45制备而成。
2、按照权利要求1所述的治疗骨折的中药制剂，其特征在于：按照重量组份计算：它由儿茶350g、红花350g、血竭70g、赤芍700g、当归350g、丹皮175g、川芎175g、香附175g、乳香43.75g、没药43.75g、乌药175g、茯苓350g、甘草52.5g、朱砂7g、琥珀14g、木香43.75g、丁香43.75g制备而成。
3、按照权利要求1、2所述的治疗骨折的中药制剂，其特征在于：所述的制剂为所有医学允许的口服制剂，包括：片、颗粒、胶囊、软胶囊、口服液、丸、散。
4、如权利要求1或2所述的治疗骨折的中药制剂的制备方法，其特征在于：称量这17味药材，除血竭、朱砂、琥珀外将赤芍、当归、红花等其余药材用水洗净，水洗过的药材干燥，干燥后的药材进行粉碎、过筛得细粉，血竭单独粉碎备用，粉碎后的群药与血竭、琥珀、朱砂混匀得本药物，然后根据需求制备成需要的剂型，可以直接压制成片剂、装入胶囊中制成胶囊剂或者加入适量的蔗糖、制备成颗粒剂或口服液制剂。
5、按照权利要求4所述的治疗骨折的中药制剂的制备方法，其特征在于：制备丸剂的方法是：称取17味药材、除血竭、朱砂、琥珀外，将赤芍、当归、红花、等群药用水洗净，水洗过的药物入干燥箱干燥，干燥箱温度控制在50℃-60℃之间，干燥后的药物入粉碎机粉碎、过五号筛使之呈细粉，血竭单独乳体粉碎备用，粉碎后的群药与血竭、琥珀、朱砂混匀，将适量蜂蜜在容器内根据标准加热炼制、过筛备用，将粉碎好的药粉和蜜以1∶1的比例入合坨机、合成药坨，合成后的药坨入蜜丸机制成每丸重6g的蜜丸。
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102247501A (zh) * | 2011-07-14 | 2011-11-23 | 崔凤玉 | 一种治疗软组织损伤的药物 |
| CN102283972A (zh) * | 2011-08-05 | 2011-12-21 | 梁兴涛 | 一种治疗肋骨骨折的药物组合物 |
| CN104147288A (zh) * | 2014-08-12 | 2014-11-19 | 潘阿海 | 一种具有舒经活血作用的中药制剂 |
| CN106075376A (zh) * | 2016-08-23 | 2016-11-09 | 斯拉甫·艾白 | 一种治疗骨折的口服制剂 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102247501A (zh) * | 2011-07-14 | 2011-11-23 | 崔凤玉 | 一种治疗软组织损伤的药物 |
| CN102283972A (zh) * | 2011-08-05 | 2011-12-21 | 梁兴涛 | 一种治疗肋骨骨折的药物组合物 |
| CN102283972B (zh) * | 2011-08-05 | 2012-12-05 | 梁兴涛 | 一种治疗肋骨骨折的药物组合物 |
| CN104147288A (zh) * | 2014-08-12 | 2014-11-19 | 潘阿海 | 一种具有舒经活血作用的中药制剂 |
| CN106075376A (zh) * | 2016-08-23 | 2016-11-09 | 斯拉甫·艾白 | 一种治疗骨折的口服制剂 |
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