CN1328513A

CN1328513A - Packing means for medicaments in form of folded box combination for at least two different primary packings

Info

Publication number: CN1328513A
Application number: CN99813707A
Authority: CN
Inventors: 科妮莉亚·沃尔瑟
Original assignee: LTS Lohmann Therapie Systeme AG
Current assignee: LTS Lohmann Therapie Systeme AG
Priority date: 1998-12-01
Filing date: 1999-11-24
Publication date: 2001-12-26
Also published as: KR20010080554A; HUP0104739A3; BR9916918A; WO2000032484A1; HUP0104739A2; JP2002531333A; AU1273200A; CA2352428A1; AR021511A1; DE19855318C1; IL143138A0; EP1135299A1

Abstract

The invention relates to a packing means for medicaments in the form of a folded box combination for at least two different primary packings, containing transdermal plasters and capsules, in the form of a cardboard folded box accommodating both medicaments. Said folded box comprises a receptacle for individual rectangular plasters to be stacked in bulk in said receptacle. Said receptacle has a structure according to DIN 55 429 with a front wall (1) and a back wall (2) with joints (26 to 30) for a folding lid (6), a folding bottom (5) and lateral walls (3, 4). The inventive packing means is characterized in that the folded box further has a punch blank part (12) which is joined by means of joints (10, 10') to the front wall (1) at both sides of a push-in slot (11) formed in between. Said punch blank part (12) comprises two flat sections (14, 15) which can be folded on top of each other along a folding line (13). A number of holes (16, 17) is arranged in said flat sections. Said punch blank part is configured to accommodate a tablet blister unit with deep-drawn tablet cups containing the capsules. Said tablet blister unit can be inserted between the flat sections (14, 15).

Description

Combination folding box pharmaceutical packaging device of at least two different basic packages

发明背景Background of the invention

在特殊情况下，生病或疾病的症状需要或建议组合疗法，其包括含有胶囊的活性成份的口服药剂，同时包括借助于活性药剂透过皮肤的系统馈给方式的辅助减慢活性疗法，使用以自粘贴药膏形式的经皮肤的治疗系统，现在已有不同形状和尺寸的药物胶囊和经皮肤药膏(TTS)提供销售，其首先是采取基本的包装，而分散的后续包装则通常采用不同形状和尺寸的折盒包装。In exceptional cases, symptoms of illness or disease require or suggest a combination therapy consisting of an oral agent containing the active ingredient in capsules combined with adjuvant slowed-active therapy by means of systemic delivery of the active agent through the skin, using Transdermal therapeutic systems in the form of self-adhesive plasters, drug capsules and transdermal plasters (TTS) are now available in different shapes and sizes, starting with basic packaging and discrete follow-up packaging usually in different shapes and sizes. sized folding box packaging.

这种情形经常导致不能同时使用药物，或者误用或忘记使用其中一种药物。然而，在任何情况下，该分散包装的药物将造成储存和应用上的问题，特别是对于在家中的患者更是如此。因此，在实际情况下，总是要求或需要经常保证正确的、组合的使用，这就使得两种不同形式的药物容纳在联合的、不分散的包装组合式结构中。This situation often results in not taking the medicines at the same time, or misusing or forgetting to take one of the medicines. In any event, however, the discretely packaged drug poses storage and application problems, especially for patients at home. Therefore, in practical situations, it is always required or necessary to ensure correct, combined use, which results in two different forms of medicaments being accommodated in a combined, non-dispersible packaged combination structure.

发明目的purpose of invention

因此，本发明的目的是设计一种组合式折盒的包装装置，以便使不同药物的两种不同基本包装可容纳在其中，并且作为联合服用的药物。而且，该组合式折盒的形状、处理和制造都很直接而简单，特别是从单坯料(Blank)中制造成一个构件的成本是非常经济的。Therefore, the object of the present invention is to devise a packaging device of the combined folding box so that two different basic packages of different medicines can be accommodated therein and as medicines to be administered in combination. Moreover, the shape, handling and manufacture of the combined folding box are all direct and simple, especially the cost of manufacturing a component from a single blank (Blank) is very economical.

有时该组合式折盒也可适合于容纳不同表面区域尺寸的TTS。发明简述Sometimes the modular bellows can also be adapted to accommodate TTSs of different surface area sizes. Brief description of the invention

为达成上述目的，本发明依据权利要求1前序部分中所述的包装装置，提出一种依照权利要求1中的特征部分所述的组合式折盒。特别是，根据本发明的折盒非常适用于同时联合和非分散地容纳两种不同的基本包装，并且本发明的折盒是由一单张空白硬纸板坯料进行制造，其成本是非常经济的。To achieve the above object, the invention proposes a combined folding box according to the characterizing part of claim 1 according to the packaging device stated in the preamble of claim 1 . In particular, the folding box according to the invention is very suitable for simultaneously joint and non-discretely containing two different basic packages, and the folding box according to the invention is manufactured from a single blank cardboard blank at a very economical cost .

依据本发明的组合式折盒结构的进一步优点，可以从从属权利要求2至6中得知。从属权利要求7和8则是描述另一种结构的组合式折盒，其中用于长方形药膏的包装空间采取一种双层壁的设计，适用于容纳不同表面区域尺寸的TTS。Further advantages of the combined bellows structure according to the invention emerge from subclaims 2 to 6 . Dependent claims 7 and 8 describe another structure of the combined folding box, wherein the packaging space for the rectangular ointment adopts a double-walled design suitable for accommodating TTS with different surface area sizes.

附图说明 Description of drawings

关于本发明的进一步的细节以及本发明的特征和优点，可以参照附图从以下两个典型实施例的概略描绘中更加明晰，其中：Further details about the present invention as well as the features and advantages of the present invention can be made clearer from the following two schematic descriptions of typical embodiments with reference to the accompanying drawings, wherein:

图1显示一个组合式折盒的坯料(blank)，一方面可以容纳长方形的基本包装的TTS药膏，另一方面可容纳有锭剂的锭剂发泡药包装，锭剂放置在一种热形成的发泡药中，并且覆盖一层铝箔；以及Figure 1 shows the blank of a combined folding box which can accommodate, on the one hand, a rectangular basic package of TTS ointment and, on the other hand, a pastille blister pack with lozenges placed in a thermoforming in foaming medicine and covered with a layer of aluminum foil; and

图2显示一种基本形状类似的折盒的坯料，但横向侧边上具有一个双层壁设计的附加的表面区域部分。FIG. 2 shows a blank for a bellows of similar basic shape, but with an additional surface area part of double-wall design on the lateral sides.

发明说明Description of the invention

图1显示用于制作组合式包装装置的折盒硬纸板的平面图，至少二种不同基本包装的组合式折盒的药物包装装置，其一方面包含经皮肤的药膏，另一方面包含胶囊，该以硬纸板制成的折盒可一起容纳所述基本包装，并且具有一个用以容纳单独的呈长方形药膏的适当空间，药膏可相互重叠散装放置。此种构造是根据DIN 55429规范，具有包括用于可插式盖子6的接合部26至30的一前面壁1和一后面壁2，接合部呈折叠线的方式；一个可插式的底座5以及横向的侧壁3，4。通过前面壁上的接合部10，10′，在一个形成于接合部之间的可插式槽缝11的两侧边，折盒还具有一冲孔的空白部分12，其包含两个表面区域部分14，15，这两部分可以围绕一条折缝线13互相摇摆呈现堆叠状况，而且在每个表面区域部分内设置有多个孔16，17，该冲孔的空白部分的设计是用来容纳一个锭剂发泡包装单元，锭剂发泡包装单元可放置在表面区域部分14，15之间，并且已经将含胶囊的锭剂发泡药热成型。Figure 1 shows a plan view of a folding box cardboard used to make a combined packaging device, a pharmaceutical packaging device of a combined folding box of at least two different basic packages, containing on the one hand a transdermal ointment and on the other hand a capsule, the A folding box made of cardboard holds the basic packages together and has a suitable space for the individual oblong ointments which can be placed in bulk on top of each other. This construction is according to the DIN 55429 specification, with a front wall 1 and a rear wall 2 comprising joints 26 to 30 for a pluggable cover 6 in the form of fold lines; a pluggable base 5 and lateral side walls 3,4. Through joints 10, 10' on the front wall, on either side of an insertable slot 11 formed between the joints, the bellows also has a punched blank 12 comprising two surface areas parts 14, 15, which can be rocked relative to each other about a crease line 13 in a stacked condition, and are provided with a plurality of holes 16, 17 in each surface area part, the blank part of the punching being designed to accommodate A blister packaging unit for pastilles, which can be placed between the surface area parts 14, 15 and has thermoformed the blister containing capsules.

孔16和17所选择的设置形式是使将锭剂的已热成型的发泡包装单元可以插置其中，以便在取出药物时，可以以熟悉的公知方式用手指触压，从而通过孔16，17挤压出发泡药。Holes 16 and 17 are chosen in such a way that the thermoformed blister packaging unit of the lozenge can be inserted therein so that when the medicine is taken out, it can be pressed with a finger in a familiar and known manner, thereby passing through hole 16, 17 extrude foaming medicine.

本发明所提供的结构的优点在于，当锭剂单元已放置就位，而且二表面区域部分14，15也已互相摇摆，则该二表面区域部分可以利用粘接剂在一条细长胶带18的辅助下相互连结。The advantage of the structure provided by the present invention is that when the lozenge unit has been placed in place and the two surface area portions 14, 15 have been rocked relative to each other, the two surface area portions can be bonded to each other by means of an adhesive on an elongated tape 18. Aided in connecting with each other.

本发明的另一特征在于，由摇摆附着在一起的表面区域部分14，15具有一个呈凹部19形式的辅助抓握部。另外，可插式折板7在前面壁1上做为一个辅助的开启部，优选形式是该开启部呈一个半圆形的凹部20。Another feature of the invention is that the surface area parts 14 , 15 attached together by the rocker have an auxiliary grip in the form of a recess 19 . In addition, the insertable flap 7 is used as an auxiliary opening on the front wall 1 , preferably in the form of a semicircular recess 20 .

本发明的结构上的一个特征是该后面壁2上，折盒的坯料具有一个可以围绕折缝线25进行折曲的胶粘折板8。所述胶粘折板可以涂复一种自粘性材料或是一种可热密封的介质。A structural feature of the invention is that on the rear wall 2 the blank of the bellows has a glued flap 8 which can be folded around a crease line 25 . The adhesive flaps can be coated with a self-adhesive material or a heat-sealable medium.

当前面壁1、后面壁2以及横向侧壁3和4已折叠定位，则胶粘折板8便可以胶粘的方式与横向侧壁3结合或构成密封，在折叠后形成一个立方型体。然后，支撑折板23、23′和24、24′分别围绕折缝线21、21′和22、22响内折弯90°而进入立方型体的内部，因此用作随后折入内部的可支撑表面区域部分5和12的支撑件。When the front wall 1, the rear wall 2, and the lateral side walls 3 and 4 have been folded and positioned, the adhesive flap 8 can be glued to the lateral side wall 3 or form a seal, forming a cubic shape after folding. Then, the support flaps 23, 23' and 24, 24' are bent inwardly by 90° about the crease lines 21, 21' and 22, 22 respectively, into the interior of the cube, thus serving as a movable part for subsequent folding into the interior. Support for supporting surface area parts 5 and 12 .

在此之前，一个锭剂发泡包装单元突伸穿透孔16或17的发泡成形物，以定位在表面区域部分14或15内，随后表面区域部分15便绕折缝线13折弯180°，并放置在表面区域部分14上，而且借助细长胶带18与表面区域部分14连结，然后向内摇摆朝向构成长方型体的开口，在可插式盖子6下方。以后，位于上方的可插式盖子6通过可插式折板7啮合在可插式槽缝11中。在相对侧边，可插式底座5也同样地翻转，借助可插式折板9啮合在一个形成于后面壁2的顶部边缘与翻转的支撑折板23和24之间的槽缝内，在步骤中将组合式折盒加以密闭。当然，上述已经完成基本包装的长方形TTS药膏是配置在前面壁1、后面壁2以及横向侧壁3和4间的最终立方型体的空穴内。这样就完成了折盒的制作；作为二次包装，其一方面容纳一个带有包含锭剂发泡药的热形成胶囊的锭剂发泡包装单元，另一方面容纳一堆长方形的TTS药膏。Prior to this, a tablet foam packaging unit protrudes through the foam molding of the hole 16 or 17 to be positioned in the surface area part 14 or 15, and the surface area part 15 is then bent 180 around the fold seam 13 °, and placed on the surface area part 14, and connected with the surface area part 14 by means of an elongated adhesive tape 18, and then swing inwards towards the opening forming the cuboid, below the pluggable cover 6. Later, the upper, pluggable cover 6 engages in the pluggable slot 11 via the pluggable flap 7 . On the opposite side, the pluggable base 5 is likewise turned over, by means of the pluggable flap 9 engaging in a slot formed between the top edge of the rear wall 2 and the turned support flaps 23 and 24, at In the step, the combined folding box is sealed. Of course, the above-mentioned rectangular TTS ointment that has completed the basic packaging is configured in the cavity of the final cubic body between the front wall 1, the rear wall 2 and the lateral side walls 3 and 4. This completes the production of the folding box; as a secondary packaging, it accommodates on the one hand a tablet blister packaging unit with a thermoformed capsule containing the tablet blister drug, and on the other hand a stack of rectangular TTS ointments.

图2的坯料与图1的坯料不同处在于，横向侧壁3，4并非呈支撑折板23′，24′的形式，而是成经过双重折缝线21′、21″；22′、22″构成的双壁的表面区域元件40，40′，所述表面区域元件设定有经过折缝线41、41′的端侧胶粘接头42，42′，而且不同处还在于在横向侧壁3，4的相对端部处并不设置支撑折板23，24，而是可经过折缝线21，22构成接合的胶粘接头43，44，该胶粘接头43，44与胶粘接头42，42′具有相同的表面区域。The blank of Fig. 2 is different from the blank of Fig. 1 in that the lateral side walls 3, 4 are not in the form of supporting flaps 23', 24', but are formed through double crease lines 21', 21"; 22', 22 "Constructed double-walled surface-area elements 40, 40', which are provided with end-side glued joints 42, 42' passing through crease lines 41, 41', and differ in that the transverse side walls The opposite ends of 3, 4 are not provided with support flaps 23, 24, but can pass through crease lines 21, 22 to form joint glued joints 43, 44, which glued joints 43, 44 and glued joints 42 , 42' have the same surface area.

当最终的组合式折盒经过折叠组装完成之后，首先表面区域部分40经由双重折缝线21′和21″平行于横向侧壁3和4翻转180°；同时，该向内折弯90°的胶粘接头42和43相互粘结。以相同方法，借助围绕双重折缝线22′和22″弯曲的表面区域部分40′，以及被粘结的胶粘接头44和42′，可在每个横向侧边上形成一个双层壁。然后，可折叠的空白坯料的其余部分便可折叠定位，以产生折盒的长方型体；以图1中的空白纸板坯料所示的相同折叠方式，将胶粘折板8粘结到横向侧壁3上，然后将锭剂发泡包装单元放置在表面区域部分14和15之间，这些都是由胶带18以胶粘方式围绕接合部10和10′向内折曲180°而相互粘结的；而且，其顶部侧由摇摆的可插式盖子6闭合，可插式折板7则是锁闩至可插式槽缝11中；一旦可插式底座5已折弯超过180度以及折板已插置入后壁12的顶侧和折缝线21和22间的间隙，则由可插式底座5在全部侧面上封闭底侧。折盒的最终长方型体内部由于双层壁的设置而减少尺寸，因此可用于容纳一堆与其表面区域尺寸相当的药膏。After the final combined folding box is folded and assembled, first the surface area part 40 is turned over 180° parallel to the lateral side walls 3 and 4 via the double crease lines 21' and 21"; at the same time, the inwardly bent 90° Glued joints 42 and 43 are bonded to each other. In the same way, by means of surface area portions 40' curved around double crease lines 22' and 22", and bonded glued joints 44 and 42', each A double wall is formed on the lateral sides. The rest of the foldable blank blank can then be folded and positioned to produce the cuboid shape of the folding box; in the same fold as shown for the blank cardboard blank in Figure 1, the glued flaps 8 are bonded to the transverse On the side wall 3, the tablet blister pack unit is then placed between the surface area parts 14 and 15, which are glued to each other by an adhesive tape 18 bent inwards 180° around the joints 10 and 10'. and, its top side is closed by a swingable pluggable lid 6, the pluggable flap 7 is latched into the pluggable slot 11; once the pluggable base 5 has been bent over 180 degrees and Having inserted the flaps into the gap between the top side of the rear wall 12 and the crease lines 21 and 22 , the bottom side is closed on all sides by the pluggable base 5 . The interior of the final cuboid body of the folding box is reduced in size due to the provision of double walls and thus can be used to accommodate a stack of ointments commensurate with the size of its surface area.

本发明所描绘的附图可知，从图1和图2所示的空白坯料中可以非常直接而简单地依据本发明的简单的折叠方式而组装成组合式折盒。在这方面本发明确可以最佳方式达到所设定的目的。It can be seen from the drawings depicted in the present invention that the blank blank shown in Fig. 1 and Fig. 2 can be assembled into a combined folding box very directly and simply according to the simple folding method of the present invention. In this respect the invention clearly achieves the set objects in the best possible way.

Claims

1. the packing means for medicaments of the compound type folding box packed substantially of at least two kinds of differences, it comprises endermic ointment on the one hand and comprises capsule in the aspect in addition, the folding box made from carboard is ccontaining described basic the packing simultaneously, and has a suitable space that is used for ccontaining can overlapped loose packed independent oblong ointment, this structure is according to DIN 55429 standards, the folding box has a front side wall (1) and a back face wall (2) that has the junction surface (26 to 30) that is used for a pluggable lid (6), one pluggable base (5) and horizontal sidewall (3,4), it is characterized in that, by the junction surface (10 on the front side wall (1), 10 '), on the plug-in type line of rabbet joint (11) dual-side that is formed between the described junction surface, this folding box also has the blank parts (12) of a punching, the blank parts of this punching comprises two can center on the surf zone part (14 that a rip out stitches (13) waves mutually, 15), and in each surf zone part, be provided with a plurality of holes (16,17), the design of the blank parts of described punching is in order to hold a lozenge blister pack unit, this lozenge blister pack unit can be placed on surf zone part (14,15) between, and will contain the lozenge vesicatory Heat forming of capsule.

2. packing device as claimed in claim 1, it is characterized in that, when lozenge unit placement positioning fully, and two surf zones parts (14 and 15) also wave mutually, and then this two surf zones part can link down mutually the auxiliary of an elongated adhesive tape (18).

3. packing device as claimed in claim 1 or 2 is characterized in that, has an auxiliary grip part that is recess (19) form by the surf zone part (14,15) of waving together.

4. as the described packing device of claim 1 to 3, it is characterized in that pluggable flap (7) is set in front side wall (1) and goes up as an auxiliary opening, preferred opening is a semi-round recess (20).

5. as the described packing device of claim 1 to 4, it is characterized in that on the wall (2), the blank blank of folding box has one and can center on the gluing flap (8) that rip out stitches (25) carries out warpage in the back.

6. as the described packing device of claim 1 to 5, it is characterized in that, by rip out stitches (21,21 '; 22,22 ') the support flap that can overturn (23,23 '; 24,24 ') be arranged on each lateral sidewalls (3,4).

7. packing device as claimed in claim 1 is characterized in that, lateral sidewalls (3,4) is not to be set to support flap (23 ' and 24 '), but set for via the two-fold suture (21 ', 21 "; 21 ', 22 ") constitute the surf zone element (40,40 ') of double wall, described surf zone components set have distolateral cemented joint (42; 42 '); and be not to be provided with to support flap (23,24); can constitute the cemented joint (43,44) that engages by rip out stitches (21; 22) but be provided with, cemented joint (43; 44) has identical face area with cemented joint (42,42 ') at the opposed end place of lateral sidewalls (3,4).

8. packing device as claimed in claim 7 is characterized in that, when surf zone part (40,40 ') with respect to the double wall (3,40 that in forming process, forms; 4,40), surf zone part (3,4) is parallel when folding, cemented joint (43,44) and cemented joint (42,42 ') can reciprocally bond.

9. as the described packing device of claim 1 to 8, it is characterized in that a pluggable flap (9) is arranged on the pluggable base (5) via a junction surface (26 ') that is designed to rip out stitches.

10. as one or several described packing devices in the claim 1 to 9, it is characterized in that compound type folding box can be operated assembling and be made into solid memder through folding and plant by cardboard blank.