CN1301114C - Miehening soft extract and powder and its preparation technology - Google Patents
Miehening soft extract and powder and its preparation technology Download PDFInfo
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- CN1301114C CN1301114C CNB011413735A CN01141373A CN1301114C CN 1301114 C CN1301114 C CN 1301114C CN B011413735 A CNB011413735 A CN B011413735A CN 01141373 A CN01141373 A CN 01141373A CN 1301114 C CN1301114 C CN 1301114C
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- 240000006995 Abutilon theophrasti Species 0.000 claims description 14
- 229940079593 drug Drugs 0.000 claims description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 7
- 229940042126 oral powder Drugs 0.000 claims description 7
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 6
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- 230000018044 dehydration Effects 0.000 claims description 4
- 238000006297 dehydration reaction Methods 0.000 claims description 4
- 235000011837 pasties Nutrition 0.000 claims description 4
- 229940098465 tincture Drugs 0.000 claims description 3
- 229960000411 camphor oil Drugs 0.000 claims description 2
- 239000010624 camphor oil Substances 0.000 claims description 2
- 238000007598 dipping method Methods 0.000 claims description 2
- 238000001914 filtration Methods 0.000 claims description 2
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 claims description 2
- 239000009637 wintergreen oil Substances 0.000 claims description 2
- 238000005538 encapsulation Methods 0.000 claims 1
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- 239000008280 blood Substances 0.000 abstract description 5
- 210000004369 blood Anatomy 0.000 abstract description 5
- 230000017531 blood circulation Effects 0.000 abstract description 4
- 239000006071 cream Substances 0.000 abstract description 4
- 238000004108 freeze drying Methods 0.000 abstract description 4
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- 241000193830 Bacillus <bacterium> Species 0.000 abstract description 2
- 244000194828 Ligularia tussilaginea Species 0.000 abstract description 2
- 235000003812 Ligularia tussilaginea Nutrition 0.000 abstract description 2
- 241000221079 Euphorbia <genus> Species 0.000 abstract 1
- 235000012043 Euphorbia helioscopia Nutrition 0.000 abstract 1
- 244000192024 Euphorbia helioscopia Species 0.000 abstract 1
- 241000746716 Typhonium Species 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
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- HPDHKHMHQGCNPE-GFIWHYBVSA-N (4z,11z)-4-ethylidene-7-hydroxy-6,7,14-trimethyl-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-3,8,17-trione Chemical compound O1C(=O)C(=C/C)\CC(C)C(C)(O)C(=O)OC\C2=C\CN(C)CCC1C2=O HPDHKHMHQGCNPE-GFIWHYBVSA-N 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The preparation progress relates to Miehening cream powder and a preparation technology thereof. The cream powder is prepared from euphorbia, giant typhonium herb, euphorbia helioscopia, ligularia tussilaginea, etc., adopts a freeze drying technique and is capable of inhibiting and killing tubercle bacillus. The cream powder has the characteristics of short treatment period, easy use, low price, etc., has the functions of tiredness resistance, detoxication, blood circulation promotion to remove blood stasis, swelling elimination and pain relief and is suitable for treating tuberculosis of each part, particularly pesticide resistant tuberculosis.
Description
Technical field
The present invention relates to a kind of treatment because mycobacterium tuberculosis infection causes the medicine of disease.
Background technology
Tuberculosis is that the traditional Chinese medical science is referred to as " consumptive disease " disease, is a kind of infectious disease, and the mankind are caused very big threat because skin, muscle, muscles and bones and the internal organs of tubercule bacillus invasion and attack damage human body very easily cause death or disability; Especially current Drug resistance tuberculosis.At present, the biochemical drug of treatment tuberculosis disease is of a great variety, but it exists weak point to be that toxic and side effects is big, and the course of treatment is long, the price height, and develop immunity to drugs.
Summary of the invention
Its order of the present invention is just is to provide a kind of treatment tuberculosis, and described treatment tuberculosis is made up of externally used paste and oral powder; Toxic and side effects is little, and short treating period overcomes Drug resistance.
The technical scheme that realizes above-mentioned purpose and take comprises:
1, externally used paste: the crude drug by shank and slave part is made, main part comprises Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 20-60g, Herba Typhonii gigantei 20-60g, Herba Euphorbiae Helioscopiae 50-150g, Olibanum 20-60g, Myrrha 20-60g, Gekko Swinhonis 5-15g, Semen Momordicae 5-15g, Nidusvespae 10-30g, Galla Chinensis 15-45g, piemarker herb 30-90g, Scolopendra 3-9 bar; Auxiliary is Moschus 0.15-0.45g partly, Borneolum Syntheticum 2.5-7.5g, Venenum Bufonis 2-6g, Flos Caryophylli 0.5-1.5g, Herba speranskiae tuberculatae 10-30g.
2, oral powder is made by crude drug piemarker herb 5-15g.
The specific embodiment
Piemarker herb: the source, this product is feverfew piemarker herb Fartugium japonicum.
Local name: Farfugium japonicum (former plant name), only sufficient lotus, Farfugium kaemferi.
Morphological characteristic: perennial herb, the tool rhizome, the base portion leaf has long handle, kidney shape, long 3-7 cun, its convex serration of edge, the room shape of head inflorescence Cheng Shusheng, the 10-12 month is opened Hemerocallis citrina Baroni, the achene cylindrical shape.
Growing environment: cultivate or wild remote mountains, trench, inferior dark and damp place, stone precipice more.
The nature and flavor function: property is flat to be slightly cold bitter in the mouth, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, alleviating pain and detumescence." the medical herbs handbook, revolutionary committee of Jindezhen City, Jiangxi Province health bureau publishes the record books, on May 1st, 1970.
The piemarker herb active ingredient is mainly: root and leaf contain renardine.The record books " practical Chinese medicine and western medicine adapted handbook, colleges and universities in Shanxi combined publication society publishes, in June, 1993 front page.
A kind of treatment tuberculosis is made up of externally used paste and oral powder:
(1) externally used paste is made by the crude drug of main part and slave part: main part comprises Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 20-60g, Herba Typhonii gigantei 20-60g, Herba Euphorbiae Helioscopiae 50-150g, Olibanum 20-60g, Myrrha 20-150g, Gekko Swinhonis 5-15g, Semen Momordicae 5-15g, Nidusvespae 10-30g, Galla Chinensis 15-45g, piemarker herb 30-90g, Scolopendra 3-9 bar; Auxiliary is Moschus 015-0.45g partly, Borneolum Syntheticum 2.5-7.5g, Venenum Bufonis 2-6g, Flos Caryophylli 0.5-1.5g, Herba speranskiae tuberculatae 10-30g.
2, oral powder is made by crude drug piemarker herb 5-15g.
One, the preparation technology of unguentum
(1) process of preparing Chinese medicine of medical material and processing
1, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae): body is done, the color HUANGBAI(sic), and free from insect pests, the high person of opaque is good, cleans, airing water is thinly sliced and is dried usefulness.
2, Herba Typhonii gigantei: thin and smooth with skin, matter is enriched, and the big person of section mealiness be good, and decontamination is cleaned, behind special processing solarization half-dried, thinly slice, dry usefulness.
3, Herba Euphorbiae Helioscopiae: gather when blooming in the 4-5 month for top grade, remove root and silt, choose decontamination, clean, the airing cutting is dried, and gives birth to and uses.
4, Olibanum: crisp with matter, the color stain is yellow, no sandstone matter, and its powder of hand rubbing glues hands, and the fragrant person that distinguishes the flavor of is good, fries when being used as medicine and uses.
5, Myrrha: for well, after smashing, fry to coke black and use with the reddish brown and hard nahlock of color.
6, Gekko Swinhonis: finish whole magnetic tape trailer person for good with body, dry with slow fire under with wire gauze, former medicine is given birth to and is used.
7, Venenum Bufonis; With Shandong the best, color Chen Yue black substance amount more is good more.
8, Semen Momordicae: full with grain, appearance is hard, the body consequence, and interior core yellow-white, bellding is not good, former medicine is shelled get the living usefulness of core.
9, Moschus: with individual big, body is soft, flat garden shape, the band undercoat, Pi Bianxiao, thin the no crape folding of skin, color is white, light, drying, the matter powder is and flexible, how completely rich oil matter, core person are good.
10, Borneolum Syntheticum: big with sheet, matter is thin, and color is pure white, and Du is crisp for matter, and clear and upright person is good for gas delicate fragrance, and the time spent can not be through fire, and levigation is used.
13, Nidus Vespae: do with body, color is white, and matter is soft, and that pinches is flexible, and middle no pupa is good.
14, Galla Chinensis: gathered before the September, put to boil in the hot water to pick up after five minutes and dry or dry, do with body, individual big, complete not broken person is good, scrapes unhairing, breaks into pieces simultaneously, and a sieve inner chip is used.
15, piemarker herb: herb is chosen roguing and is gone after gathering, and cleans using fresh herb.
16, Herba speranskiae tuberculatae (Flos Impatientis): do with body, no worm, medicinal kind and herb are given birth to usefulness, clean airing, and decontamination is cut into slices and segment is used.
17, additive: ethanol content is the 60-95 degree, wintergreen oil, white camphor oil.
(2) preparing process
1, medicine Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 20-60g that roughing is good, Herba Typhonii gigantei 20-60g, Herba Euphorbiae Helioscopiae 50-150g, Olibanum 20-60g, Myrrha 20-60g, Gekko Swinhonis 5-15g, Semen Momordicae 5-15g, Scolopendra 3-9 bar, Nidusvespae 10-30g, Galla Chinensis 15-45g, piemarker herb 30-90g pulverize and are the end, store for powder-tight in cryogenic vacuum dehydration back then.The cryogenic vacuum dehydration comprises vacuum drying, microwave vacuum drying, vacuum lyophilization.
2, with Moschus 0.15-0.45g, Borneolum Syntheticum 2.5-7.5g, Venenum Bufonis 2-6g, Flos Caryophylli 0.5-1.5g, Herba speranskiae tuberculatae 10-30 content is 60-80 degree alcohol dipping, converting behind the filtering residue and making ethanol content is that 30% solution stores, and seals in the small plastic bag that makes of packing into then.
3, the drug powder made is enclosed on the plaster carrier sealed, put into packaging bag, the branch seed oil tincture preparation of will living is simultaneously put into packaging bag and is sealed.
Two, the preparation technology of powder
(1) medical material processing
Eight usefulness crow: root, stem, leaf all herbal medicine, clean and dry, decontamination section section using fresh herb.
(2) preparing process
1, earlier the medicine piemarker herb is made pasty state.
2, pasty medicament is put into the cryogenic vacuum environment and dewatered, the cryogenic vacuum environment comprises vacuum drying, microwave vacuum drying, vacuum lyophilization.
3, the evacuation of dehydrated powder being packed in the plastic bag that makes is sealed up for safekeeping.
Three, overall package
With externally used paste and oral powder with in the external packing box of packing into, using method, consumption, taboo with and description put into box simultaneously and get final product.
Four, medicinal efficacy
The present invention, cream is topical drug, looses to be medicine for oral administration, can use simultaneously in treatment lysis, also can use separately.
Function: anti-consumptive disease detoxifcation, the promoting blood circulation and hemostasis dissipating blood stasis, reducing swelling and alleviating pain, relieving cough and resolving phlegm are relievingd asthma, and qualcomm meridian is had one's ideas straightened out.
Indication: cure mainly each position tuberculosis, epidemic febrile disease cough (pneumonia), asthma, traumatic blood stasis, hemorrhage, carbuncle, furuncle, mumps malignant boil.
Compared with prior art, the present invention has the following advantages:
1, owing to adopted the multidigit Chinese herbal medicine, especially adopted the treatment means of " inner disease outer treat, internal and external application, the exterior and the interior are also controlled ", anistree nothing good heat-clearing and toxic substances removing in filling a prescription simultaneously, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain effect.At various tuberculosis, particularly Drug resistance tuberculosis tuberculosis has better curative effect; Have that toxic and side effects is little, short treating period, low-cost characteristics.
2,, thereby have the fresh aquatic food effect that keeps pharmaceutical compositions owing to adopted freeze drying technology (vacuum dehydration drying), and the technology characteristic of simple.
Claims (2)
1, a kind of treatment tuberculosis is made up of externally used paste and oral powder, it is characterized in that:
(1) externally used paste is synthetic by shank unguentum and auxiliary partly oily tincture: the main part crude drug is made up of Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 20-60g, Herba Typhonii gigantei 20-60g Herba Euphorbiae Helioscopiae 50-150g, Olibanum 20-60g, Myrrha 20-60g, Gekko Swinhonis 5-15g Semen Momordicae 5-15g Nidus Vespae 10-30g Galla Chinensis 15-45g, piemarker herb 30-90g, Scolopendra 3-9 bar; Auxiliary partly raw material is made up of Moschus 0.15-0.45g, Borneolum Syntheticum 2.5-7.5g Venenum Bufonis 2-6g, Flos Caryophylli 0.5-1.5g Herba speranskiae tuberculatae 10-30g.
(2) oral powder is made by crude drug piemarker herb 5-15g.
2, the preparation technology of treatment tuberculosis medicine is:
(1) unguentum: shank crude drug Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 20-60g, Herba Typhonii gigantei 20-60g, Herba Euphorbiae Helioscopiae 50-150g, Olibanum 20-60g, Myrrha 20-60g, Gekko Swinhonis 5-15g, Semen Momordicae 5-15g, Nidus Vespae 10-30g, Galla Chinensis 15-45g, piemarker herb 30-90g, Scolopendra 3-9g bar are pulverized for not, then in cryogenic vacuum dehydration back sealed storage.
To assist partly crude drug Moschus 0.15-0.45g, Borneolum Syntheticum 2.5-7.5g, Venenum Bufonis 2-6g Flos Caryophylli 0.5-1.5g, Herba speranskiae tuberculatae 10-30g, with content 60-80% alcohol dipping, convert behind the filtering residue and make that to contain alcohol be 30% solution, be blended into wintergreen oil simultaneously, white camphor oil stores, encapsulation then
With sealing on the paste medicine powder inclosure unguentum carrier of making, then packaged oily tincture and unguentum are packaged in the same bag.
(2) powder: earlier the crude drug piemarker herb is made pasty state; Pasty medicament placed in the low temperature environment dewater; The powder vacuum preservation will dewater.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011413735A CN1301114C (en) | 2001-10-26 | 2001-10-26 | Miehening soft extract and powder and its preparation technology |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB011413735A CN1301114C (en) | 2001-10-26 | 2001-10-26 | Miehening soft extract and powder and its preparation technology |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1413612A CN1413612A (en) | 2003-04-30 |
| CN1301114C true CN1301114C (en) | 2007-02-21 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNB011413735A Expired - Fee Related CN1301114C (en) | 2001-10-26 | 2001-10-26 | Miehening soft extract and powder and its preparation technology |
Country Status (1)
| Country | Link |
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| CN (1) | CN1301114C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN100391507C (en) * | 2004-05-13 | 2008-06-04 | 余炜 | Method of preparing medicine for treating condyloma acuminatum |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1106671A (en) * | 1994-03-31 | 1995-08-16 | 焦安国 | External use plaster for treatment of tuberculosis |
| CN1176823A (en) * | 1997-10-08 | 1998-03-25 | 王树波 | Plaster for removing five toxic substances |
-
2001
- 2001-10-26 CN CNB011413735A patent/CN1301114C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1106671A (en) * | 1994-03-31 | 1995-08-16 | 焦安国 | External use plaster for treatment of tuberculosis |
| CN1176823A (en) * | 1997-10-08 | 1998-03-25 | 王树波 | Plaster for removing five toxic substances |
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| Publication number | Publication date |
|---|---|
| CN1413612A (en) | 2003-04-30 |
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Granted publication date: 20070221 Termination date: 20101026 |