CN1370559A - Anti-senility antilipemic nutritious health care soft capsule and its prepn - Google Patents
Anti-senility antilipemic nutritious health care soft capsule and its prepn Download PDFInfo
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- CN1370559A CN1370559A CN01106209A CN01106209A CN1370559A CN 1370559 A CN1370559 A CN 1370559A CN 01106209 A CN01106209 A CN 01106209A CN 01106209 A CN01106209 A CN 01106209A CN 1370559 A CN1370559 A CN 1370559A
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- miscella
- seed
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- soft capsule
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- 239000007901 soft capsule Substances 0.000 title claims abstract description 28
- 230000002402 anti-lipaemic effect Effects 0.000 title claims abstract description 17
- 235000008935 nutritious Nutrition 0.000 title claims abstract description 16
- 230000003005 anti-senility effect Effects 0.000 title abstract 3
- 241000191896 Rana sylvatica Species 0.000 claims abstract description 25
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 24
- 238000000605 extraction Methods 0.000 claims abstract description 17
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 12
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 12
- 229940046009 vitamin E Drugs 0.000 claims abstract description 12
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 12
- 239000011709 vitamin E Substances 0.000 claims abstract description 12
- 239000012535 impurity Substances 0.000 claims abstract description 5
- 238000002360 preparation method Methods 0.000 claims abstract description 4
- 235000003935 Hippophae Nutrition 0.000 claims description 40
- 241000229143 Hippophae Species 0.000 claims description 40
- 239000000843 powder Substances 0.000 claims description 28
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 24
- 102000002322 Egg Proteins Human genes 0.000 claims description 24
- 108010000912 Egg Proteins Proteins 0.000 claims description 24
- 210000004681 ovum Anatomy 0.000 claims description 24
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 13
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 12
- 239000001569 carbon dioxide Substances 0.000 claims description 12
- 230000018044 dehydration Effects 0.000 claims description 12
- 238000006297 dehydration reaction Methods 0.000 claims description 12
- 238000000194 supercritical-fluid extraction Methods 0.000 claims description 12
- 239000000203 mixture Substances 0.000 claims description 8
- 238000000926 separation method Methods 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 239000000284 extract Substances 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 7
- 229930003231 vitamin Natural products 0.000 claims description 5
- 239000011782 vitamin Substances 0.000 claims description 5
- 229940088594 vitamin Drugs 0.000 claims description 5
- 235000013343 vitamin Nutrition 0.000 claims description 5
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 5
- 206010013786 Dry skin Diseases 0.000 claims description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 4
- 238000013019 agitation Methods 0.000 claims description 4
- 229910052799 carbon Inorganic materials 0.000 claims description 4
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 4
- 239000003292 glue Substances 0.000 claims description 4
- 235000016709 nutrition Nutrition 0.000 claims description 4
- 230000035764 nutrition Effects 0.000 claims description 4
- 238000012216 screening Methods 0.000 claims description 4
- 239000007921 spray Substances 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 238000002156 mixing Methods 0.000 claims description 3
- 235000013305 food Nutrition 0.000 abstract description 3
- 235000021122 unsaturated fatty acids Nutrition 0.000 abstract description 2
- 240000000950 Hippophae rhamnoides Species 0.000 abstract 1
- 235000003145 Hippophae rhamnoides Nutrition 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 231100000957 no side effect Toxicity 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 5
- 208000031226 Hyperlipidaemia Diseases 0.000 description 3
- 208000024172 Cardiovascular disease Diseases 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 208000026106 cerebrovascular disease Diseases 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000002526 effect on cardiovascular system Effects 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- YMTINGFKWWXKFG-UHFFFAOYSA-N fenofibrate Chemical compound C1=CC(OC(C)(C)C(=O)OC(C)C)=CC=C1C(=O)C1=CC=C(Cl)C=C1 YMTINGFKWWXKFG-UHFFFAOYSA-N 0.000 description 1
- 229960002297 fenofibrate Drugs 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 230000000055 hyoplipidemic effect Effects 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- -1 polyene unsaturated fatty acid Chemical class 0.000 description 1
- 235000020795 whole food diet Nutrition 0.000 description 1
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- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Abstract
The present invention is anti-senility antilipemic nutritious health care soft capsule and its preparation. The effective components extracted from woodfrog egg, sea-buckthorn and other natural food material by using supercritical CO2 extraction method is produced into soft capsule. The said capsule contains several polyenic unsaturated fatty acids and vitamin E with antilipemic, anti-senility and beautifying functions and no solvent and impurity. The present invention has no side effect and is especially suitable for use by women.
Description
The present invention relates to a kind of defying age, Antilipemic nutritious health care soft capsule and method for making thereof.
Hyperlipidemia easily causes cardiovascular and cerebrovascular disease, and in recent years, the generation of hyperlipidemia is more and more higher, for blood fat reducing, suppresses the generation of cardiovascular and cerebrovascular disease, in the prior art mostly is to adopt medicine to wait as " fenofibrate " to cure hyperlipidemia.These hypolipidemics all have certain side effect because all be synthetic drug mostly.
The objective of the invention is in order to overcome above-mentioned deficiency,, adopt food and nutriment, propose a kind of defying age of being free from side effects, Antilipemic nutritious health care soft capsule and method for making thereof according to the reason of integration of edible and medicinal herbs.
The present invention is achieved using the following method.
Defying age, Antilipemic nutritious health care soft capsule have the edible soft capsule skin, be packaged with defying age, Antilipemic nutritious health care preparation at the edible soft capsule Intradermal, the composition of defying age, nutrition and health care agent and the weight portion of each component are: forest frog's egg fat 3900～4100, Fructrs Hippophae seed oil 5900～6100, vitamin E 10～15, above-mentioned forest frog's egg fat, Fructrs Hippophae seed oil all are the methods with carbon dioxide supercritical fluid extraction, the oily liquids that extracts from wood frog ovum, seed of Fructus Hippophae, vitamin E be content 〉=92%, meet the vitamin E of pharmacopeia regulation.
Above-mentioned defying age, the method for making of Antilipemic nutritious health care soft capsule is: earlier the wood frog ovum of removing impurity through screening, seed of Fructus Hippophae is dried to water content under 70～80 ℃ temperature be 7～9%, then with pulverizer respectively dried wood frog ovum, seed of Fructus Hippophae is ground into 50～80 purpose powder, again above-mentioned wood frog ovum powder and seed of Fructus Hippophae powder are extracted with carbon dioxide supercritical fluid extraction equipment respectively, the extraction conditions of wood frog ovum powder is: extracting pressure 26～30MPa, 33～37 ℃ of extraction temperature, flash trapping stage pressure 10.5～11.5MPa, secondary separating pressure 5～6Mpa, 38～42 ℃ of separation temperatures, the extraction conditions of seed of Fructus Hippophae powder is: extracting pressure 16～20MPa, 42～46 ℃ of extraction temperature, flash trapping stage pressure 10.5～11.5MPa, secondary separating pressure 5～6Mpa, 38～42 ℃ of separation temperatures, after above-mentioned wood frog ovum powder and seed of Fructus Hippophae powder extract with the method for carbon dioxide supercritical fluid extraction, obtain oily liquids, be respectively forest frog's egg fat and Fructrs Hippophae seed oil, get above-mentioned forest frog's egg fat 3900～4100 more by weight, Fructrs Hippophae seed oil 5900～6100, vitamin E 10～15 is put into blend tank, mixing and stirring, be weight that 0.6% the saline solution that boils of above-mentioned miscella weight 10～15% sprays in the above-mentioned miscella more under agitation, miscella is heated to 80 ℃ and be incubated 6～8 hours, soften dehydration, discard water layer after the softening dehydration, obtain clarifying miscella, again clarifying miscella is heated to 105～110 ℃ of dryings, no steam bubble produces in clarifying miscella, at last softening dehydration and dried clarifying miscella are made soft capsule with glue ball machine, every heavy 0.5 of soft capsule or 1 gram.
Product of the present invention is that the active ingredient that the method for employing carbon dioxide supercritical fluid extraction is extracted in the wholefoods such as wood frog ovum, seed of Fructus Hippophae is made, contain multiple polyene unsaturated fatty acid and vitamin E in the product, has stronger effect for reducing blood fat, vitamin E can also prevent the product oxidative rancidity, forest frog's egg fat and Fructrs Hippophae seed oil all have the effect of tangible anti aging effect, crease-resistant skin maintenance in addition, be free from side effects after the food, be particularly suitable for the women and eat.
Below in conjunction with embodiment, the present invention is further illustrated.
Defying age, Antilipemic nutritious health care soft capsule have the edible soft capsule skin, be packaged with defying age, Antilipemic nutritious health care preparation at the edible soft capsule Intradermal, the composition of defying age, nutrition and health care agent and the weight portion of each component are: forest frog's egg fat 4000, Fructrs Hippophae seed oil 5987, vitamin e1 3, above-mentioned forest frog's egg fat, Fructrs Hippophae seed oil all are the methods with carbon dioxide supercritical fluid extraction, the oily liquids that extracts from wood frog ovum, seed of Fructus Hippophae, vitamin E be content 〉=92%, meet the vitamin E of pharmacopeia regulation.
Above-mentioned defying age, the method for making of Antilipemic nutritious health care soft capsule is: earlier the wood frog ovum of removing impurity through screening, seed of Fructus Hippophae is dried to water content under 70～80 ℃ temperature be 8%, then with pulverizer respectively dried wood frog ovum, seed of Fructus Hippophae is ground into 80 purpose powder, again above-mentioned wood frog ovum powder and seed of Fructus Hippophae powder are extracted with carbon dioxide supercritical fluid extraction equipment respectively, the extraction conditions of wood frog ovum powder is: extracting pressure 28MPa, 35 ℃ of extraction temperature, flash trapping stage pressure 11MPa, secondary separating pressure 5.5Mpa, 40 ℃ of separation temperatures, the extraction conditions of seed of Fructus Hippophae powder is: extracting pressure 18MPa, 44 ℃ of extraction temperature, flash trapping stage pressure 11MPa, secondary separating pressure 5.5Mpa, 40 ℃ of separation temperatures, above-mentioned wood frog ovum powder and seed of Fructus Hippophae powder are oily liquids with the extract of carbon dioxide supercritical fluid extraction, be respectively forest frog's egg fat and Fructrs Hippophae seed oil, get above-mentioned forest frog's egg fat 4000 more by weight, Fructrs Hippophae seed oil 5987, vitamin e1 3, put into blend tank, mixing and stirring, be weight that 0.6% the saline solution that boils of above-mentioned miscella weight 10～15% sprays in the above-mentioned miscella more under agitation, miscella is heated to 80 ℃ and be incubated 6～8 hours, soften dehydration, discard water layer after the softening dehydration, obtain clarifying miscella, again clarifying miscella is heated to 105～110 ℃ of dryings, no steam bubble produces in clarifying miscella, at last softening dehydration and dried clarifying miscella are made soft capsule with glue ball machine, every heavy 0.5 of soft capsule or 1 gram.
Claims (4)
1. a defying age, Antilipemic nutritious health care soft capsule, the edible soft capsule skin is arranged, it is characterized in that: be packaged with defying age, Antilipemic nutritious health care preparation at the edible soft capsule Intradermal, the composition of defying age, nutrition and health care agent and the weight portion of each component are: forest frog's egg fat 3900～4100, Fructrs Hippophae seed oil 5900～6100, vitamin e1 0～15, above-mentioned forest frog's egg fat, Fructrs Hippophae seed oil all are the methods with carbon dioxide supercritical fluid extraction, the oily liquids that extracts from wood frog ovum, seed of Fructus Hippophae, vitamin E be content 〉=92%, meet the vitamin E of pharmacopeia regulation.
2. by the described defying age of claim 1, Antilipemic nutritious health care soft capsule, it is characterized in that: the composition of described defying age, nutrition and health care agent and the weight portion of each component are: forest frog's egg fat 4000, Fructrs Hippophae seed oil 5987, vitamin e1 3.
3. described defying age of claim 1, the method for making of Antilipemic nutritious health care soft capsule, it is characterized in that: earlier the wood frog ovum of removing impurity through screening, seed of Fructus Hippophae is dried to water content under 70～80 ℃ temperature be 7～9%, then with pulverizer respectively dried wood frog ovum, seed of Fructus Hippophae is ground into 50～80 purpose powder, again above-mentioned wood frog ovum powder and seed of Fructus Hippophae powder are extracted with carbon dioxide supercritical fluid extraction equipment respectively, the extraction conditions of wood frog ovum powder is: extracting pressure 26～30MPa, 33～37 ℃ of extraction temperature, flash trapping stage pressure 10.5～11.5MPa, secondary separating pressure 5～6Mpa, 38～42 ℃ of separation temperatures, the extraction conditions of seed of Fructus Hippophae powder is: extracting pressure 16～20MPa, 42～46 ℃ of extraction temperature, flash trapping stage pressure 10.5～11.5MPa, secondary separating pressure 5～6Mpa, 38～42 ℃ of separation temperatures, above-mentioned wood frog ovum powder and seed of Fructus Hippophae powder are oily liquids with the extract of carbon dioxide supercritical fluid extraction, be respectively forest frog's egg fat and Fructrs Hippophae seed oil, get above-mentioned forest frog's egg fat 3900～4100 more by weight, Fructrs Hippophae seed oil 5900～6100, vitamin E 10～15 is put into blend tank, stir, be weight that 0.6% the saline solution that boils of above-mentioned miscella weight 10～15% sprays in the above-mentioned miscella more under agitation, miscella is heated to 80 ℃ and be incubated 6～8 hours, soften dehydration, discard water layer after the softening dehydration, obtain clarifying miscella, again clarifying miscella is heated to 105～110 ℃ of dryings, no steam bubble produces in clarifying miscella, at last softening dehydration and dried clarifying miscella are made soft capsule with glue ball machine, every heavy 0.5 of soft capsule or 1 gram.
4. by the described defying age of claim 3, the method for making of Antilipemic nutritious health care soft capsule, it is characterized in that: earlier the wood frog ovum of removing impurity through screening, seed of Fructus Hippophae is dried to water content under 70～80 ℃ temperature be 8%, then with pulverizer respectively dried wood frog ovum, seed of Fructus Hippophae is ground into 80 purpose powder, again above-mentioned wood frog ovum powder and seed of Fructus Hippophae powder are extracted with carbon dioxide supercritical fluid extraction equipment respectively, the extraction conditions of wood frog ovum powder is: extracting pressure 28MPa, 35 ℃ of extraction temperature, flash trapping stage pressure 11MPa, secondary separating pressure 5.5Mpa, 40 ℃ of separation temperatures, the extraction conditions of seed of Fructus Hippophae powder is: extracting pressure 18MPa, 44 ℃ of extraction temperature, flash trapping stage pressure 11MPa, secondary separating pressure 5.5Mpa, 40 ℃ of separation temperatures, above-mentioned wood frog ovum powder and seed of Fructus Hippophae powder are oily liquids with the extract of carbon dioxide supercritical fluid extraction, be respectively forest frog's egg fat and Fructrs Hippophae seed oil, get above-mentioned forest frog's egg fat 4000 more by weight, Fructrs Hippophae seed oil 5987, vitamin e1 3, put into blend tank, mixing and stirring, be weight that 0.6% the saline solution that boils of above-mentioned miscella weight 10～15% sprays in the above-mentioned miscella more under agitation, miscella is heated to 80 ℃ and be incubated 6～8 hours, soften dehydration, discard water layer after the softening dehydration, obtain clarifying miscella, again clarifying miscella is heated to 105～110 ℃ of dryings, no steam bubble produces in clarifying miscella, at last softening dehydration and dried clarifying miscella are made soft capsule with glue ball machine, every heavy 0.5 of soft capsule or 1 gram.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN01106209A CN1370559A (en) | 2001-02-27 | 2001-02-27 | Anti-senility antilipemic nutritious health care soft capsule and its prepn |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN01106209A CN1370559A (en) | 2001-02-27 | 2001-02-27 | Anti-senility antilipemic nutritious health care soft capsule and its prepn |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1370559A true CN1370559A (en) | 2002-09-25 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN01106209A Pending CN1370559A (en) | 2001-02-27 | 2001-02-27 | Anti-senility antilipemic nutritious health care soft capsule and its prepn |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103989172A (en) * | 2014-05-26 | 2014-08-20 | 河南科技大学第一附属医院 | Soft capsule with function of reducing blood fat and blood pressure and preparation process thereof |
| CN103989171A (en) * | 2014-05-26 | 2014-08-20 | 河南科技大学第一附属医院 | Soft capsule with functions of resisting aging and maintaining beauty and keeping young and preparation process thereof |
| CN105919134A (en) * | 2016-04-22 | 2016-09-07 | 吉林大学 | Method for assisting in extracting wood frog spawn oil by ultrasonic method and preparation method of wood frog spawn oil microcapsules |
| CN108783415A (en) * | 2018-05-16 | 2018-11-13 | 林万君 | Wood frog peptide zaocys dhumnade seabuckthorn fruit powder |
-
2001
- 2001-02-27 CN CN01106209A patent/CN1370559A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103989172A (en) * | 2014-05-26 | 2014-08-20 | 河南科技大学第一附属医院 | Soft capsule with function of reducing blood fat and blood pressure and preparation process thereof |
| CN103989171A (en) * | 2014-05-26 | 2014-08-20 | 河南科技大学第一附属医院 | Soft capsule with functions of resisting aging and maintaining beauty and keeping young and preparation process thereof |
| CN103989172B (en) * | 2014-05-26 | 2015-10-14 | 河南科技大学第一附属医院 | A kind of have reducing blood lipid, the soft capsule of blood pressure reduction effect and preparation technology thereof |
| CN103989171B (en) * | 2014-05-26 | 2015-11-11 | 河南科技大学第一附属医院 | A kind of anti-aging beauty-care face-nourishing soft capsules and preparation technology thereof |
| CN105919134A (en) * | 2016-04-22 | 2016-09-07 | 吉林大学 | Method for assisting in extracting wood frog spawn oil by ultrasonic method and preparation method of wood frog spawn oil microcapsules |
| CN108783415A (en) * | 2018-05-16 | 2018-11-13 | 林万君 | Wood frog peptide zaocys dhumnade seabuckthorn fruit powder |
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