CN1364610A

CN1364610A - Blood sugar reducing tea

Info

Publication number: CN1364610A
Application number: CN01111020A
Authority: CN
Inventors: 薛志祥
Original assignee: Individual
Current assignee: Individual
Priority date: 2001-03-20
Filing date: 2001-03-20
Publication date: 2002-08-21
Anticipated expiration: 2021-03-20
Also published as: CN1169538C

Abstract

The blood sugar reducing tea as a pure Chinese medicine preparation is granule prepared by using Polygonati odorati, Radix Puerariae, Astragalus membranaceus, Chinese yam, pumpkin and other 11 kinds of Chinese medicinal materials and through special extraction, concentration and other processes. The medicine preparation is the functions of nourishing Yin and promoting the secretion of saliva, and has the diabetes treating effect and no toxic side reaction.

Description

Blood-sugar reducing tea

A kind of pure Chinese medicinal preparation " blood-sugar reducing tea " for the treatment of diabetes.

Diabetes spp traditional Chinese medical science diabetes category, how excessive by eating wine, appearance food delicious food, the long-pending heat of middle Jiao, or overaction of the five emotions, strongly fragrant and heat-transformation; Or indulge in sensual pleasures excessively, deficiency-fire stirring up, the kidney essense consume, the deficiency of YIN is scorching, reciprocal causation, and the emphasis that cloudy body fluid deficiency void is primary disease.So it is controlled and can not denudate, and should nourish; Can not how mend clearly with sweet cold and work as with vivid and substantial product.Blood sugar lowering Camellia pure natural raw material is formulated meticulously.Rhizoma Polygonati Odorati in the side, sweet and be slightly cold, nourishing YIN to relieve dryness is slaked thirst and help produce saliva; Radix Puerariae is sweet flat, lightly floats to rise to float, and the elevate a turnable ladder clearing heat in QI system can inspire gastric qi up with born fluid; Radix Astragali sweet in the mouth, though tepor is distinguished the flavor of light air supporting and cloth is precise and tiny, strengthening the spleen and stomach and help fortuneization; Rhizoma Dioscoreae is sweet flat, arrogates to oneself the spleen reinforcing nourishing the stomach, YIN nourishing and the production of body fluid promoting, and many controlling with it of this four medicines ancient Chinese medicine doctor quenched one's thirst.People find the single Fructus Cucurbitae moschatae for a long time, and Semen Glycines promptly has curative effect preferably to NTDDM.Fructus Momordicae charantiae confirms that through pharmacological evaluation similar insulin action is arranged.By reducing HbAlc concentration in the blood, improve carbohydrate tolerance, blood sugar lowering, Galla Chinensis has another name called Conch Meretricis seu Cyclinae, the Compendium of Material Medica record: the Galla Chinensis bar draws " getting efficacious prescriptions " to be controlled and quenches one's thirst, and grinds clothes into powder with Galla Chinensis 1 flavor; " Galla Chinensis ..., say Mass Galla chinesis et camelliae Fermentata by the name of legal system, the energy promoting the production of body fluid to quench thirst is tasted and is used it greatly, proves successful in every test ".Bulbus Allii sterilizes again and controls diabetes; The Radix Glycyrrhizae sweet in the mouth can ease up, but flavoring again.Cortex Cinnamomi can be activated the respond of adipose cell to insulin again, accelerates the metabolic processes of glucose greatly.In addition, cinnamomic adapted promptly can the seasoning appetite stimulator, facilitating digestion, and building body can play good prevention effect to type-II diabetes again.Make a general survey of full side, the residence medicine is among drinking tea, but blood sugar lowering not only, and can eliminate the thirsty and misery of polydipsia of diabetes, taking convenience, good mouthfeel.

Therefore, medicine of the present invention is to be the medicinal tea Chinese patent medicine that feedstock production forms with following pharmaceutical composition.

Rhizoma Polygonati Odorati 100-200 gram; Radix Puerariae 100-200 gram; Radix Astragali 100-200 gram; Rhizoma Dioscoreae 100-200 gram; Fructus Cucurbitae moschatae 100-200 gram; Fructus Momordicae charantiae 100-200 gram; Semen Glycines 100-200 gram; Galla Chinensis 50-100 gram; Green tea 50-100 gram; The fragrant 50-100 gram of fire; Ootheca Mantidis 50-100 gram; Bulbus Allii 50-100 gram; Radix Glycyrrhizae 50-100 gram; Pollen 50-100 gram; Plumula Nelumbinis 50-100 gram; Cortex Cinnamomi 50-100 restrains (weight portion)

The preferred weight proportioning of pharmaceutical composition of the present invention is:

Rhizoma Polygonati Odorati 100; Radix Puerariae 100; The Radix Astragali 100; Rhizoma Dioscoreae 100; Fructus Cucurbitae moschatae 100; Fructus Momordicae charantiae 100; Semen Glycines 100; Galla Chinensis 50; Green tea 50; Fire fragrant 50; Ootheca Mantidis 50; Bulbus Allii 50; Radix Glycyrrhizae 50; Pollen 50; Plumula Nelumbinis 50; Cortex Cinnamomi 50 (weight portion).

Pharmaceutical composition of the present invention can be prepared into any pharmaceutical preparation that is suitable for using clinically according to conventional formulation technology.For example: granule, oral liquid, electuary.

Process for preparing medicine of the present invention is:

1, selected crude drug: selected high-quality Chinese crude drug, to remove impurity, and differentiate and the run-of-the-mill check by pharmacopeia regulation, defective medical material such as of poor quality, as to go bad, damage by worms, go mouldy must not use.

2; polish: above-mentioned each combination ingredient medicine is added 8 times of water loggings or do not have powder 2-3cm; heating decocts 2 hours after-filtration; medicinal residues add 4 times of amounts of water again; heating for the second time decocts and filtered in 1 hour again; the merging filtrate low-temperature evaporation; be concentrated into half amount of original volume, add 95% ethanol equivalent mixing and spend the night and make sedimentation, supernatant inclines; ethanol is reclaimed in distillation; revaporization concentrates, and puts cold place and precipitation is filtered fully in 24 hours, and the filtrate low-temperature evaporation is to dense shape (water content 20%); add an amount of excipient mixing; make soft material with 70% ethanol, move to granulation machine 12 orders and granulate, put in the baking oven dry again under the low temperature; remove than fine grained and make evenly, 10 gram bubbles are packed.Every gram contains crude drug 2 grams.

Observation of curative effect and result:

One, be divided into treatment group and matched group at random, the former 50 examples, the latter's 50 examples, the two sports, diet control are all identical.Then orally-taken blood sugar reducing tea is organized in treatment, and arbitrarily drink it every day, and matched group orally uses oral antidiabetic drug class or insulin injection routinely.

Two, two groups respectively at 4 weeks of treatment back, whether controls with clinical symptoms after June, and blood glucose, level of sugar are as main evaluation criteria, and blood TCH, BM1 are reference.

Produce effects: transference cure, fasting glucose＜6.01mmol/L, or post-prandial glycemia＜7.77mmol/L, glucose in urine (), TCH descends obviously.

The middle effect: symptom disappears substantially, fasting glucose 6.11-7.77mmo1/L, or post-prandial glycemia 7.77-11.1mmol/L, and glucose in urine (), TCH descends less than 10 percentage points.

Little effect: the rarely seen alleviation of symptom, fasting glucose 7.77-9.99mmol/L, or post-prandial glycemia 11.1-12.77mmol/L, glucose in urine reduces, but still (±)～(+), TCH does not have improvement.

Invalid: sx does not have improvement, fasting glucose＞9.99mmol/L, or post-prandial glycemia＞12.77mmol/L, and glucose in urine exists sometimes ++ more than, TCH＞6.5mmol/L.

The result: two groups of curative effects see Table 1,2,3 table 1 treatment groups and the back curative effect comparison sheet of matched group respectively all around

Imitate the invalid group example of little effect total effective rate number in the produce effects

50 examples 2,4% 30 60% 15 30% 47 94% 3 6% matched groups, 50 examples 6 12% 25 50% 10 20% 41 82% 9 18% are organized in example number % example number % example number % example number % example number % treatment

P＜0.05 P＞0.05 table 2 treatment group and matched group curative effect comparison sheet after 6 months

50 examples 35,70% 10 20% 4 8% 49 98% 1 2% matched groups, 50 examples 33 66% 9 18% 6 12% 48 96% 2 4% are organized in example number % example number % example number % example number % example number % treatment

The P value all＞0.05 table 3 liang group treatment June after, blood pressure and blood lipoid content

(mmol/L) decline situation (X ± S) compare

50 examples 4.01 ± 1.56 4.56 ± 1.97 1.50 ± 0.49 matched groups, 50 examples 3.99 ± 1.55 4.58 ± 1.96 0.35 ± 0.26P value＞0.05＞0.05＜0.01 are organized in the treatment of fasting glucose post-prandial glycemia TCH group example number

Claims

Blood-sugar reducing tea

1, a kind of pure Chinese medicine for the treatment of diabetes is drunk medicinal tea---blood-sugar reducing tea.

It is characterized in that the medicament that is prepared from according to following proportioning with Rhizoma Polygonati Odorati, Radix Puerariae, the Radix Astragali, Rhizoma Dioscoreae, Fructus Cucurbitae moschatae, Fructus Momordicae charantiae, Semen Glycines, Galla Chinensis, green tea, fire perfume, Ootheca Mantidis, Bulbus Allii, Radix Glycyrrhizae, pollen, Plumula Nelumbinis, Cortex Cinnamomi:

Rhizoma Polygonati Odorati 100-200 gram;

Radix Puerariae 100-200 gram;

Radix Astragali 100-200 gram;

Rhizoma Dioscoreae 100-200 gram;

Fructus Cucurbitae moschatae 100-200 gram;

Fructus Momordicae charantiae 100-200 gram;

Semen Glycines 100-200 gram;

Galla Chinensis 50-100 gram;

Green tea 50-100 gram;

The fragrant 50-100 gram of fire;

Ootheca Mantidis 50-100 gram;

Bulbus Allii 50-100 gram;

Radix Glycyrrhizae 50-100 gram;

Pollen 50-100 gram;

Plumula Nelumbinis 50-100 gram;

Cortex Cinnamomi 50-100 restrains (weight portion).

2, according to claims 1 described Chinese medicine, it is characterized in that Rhizoma Polygonati Odorati and Radix Puerariae, the Radix Astragali and Rhizoma Dioscoreae, Fructus Cucurbitae moschatae and Fructus Momordicae charantiae, Semen Glycines and Galla Chinensis, green tea and Bulbus Allii, fiery perfume (or spice) and Ootheca Mantidis, pollen and Plumula Nelumbinis, Radix Glycyrrhizae and cinnamomic proportioning are:

Rhizoma Polygonati Odorati 100; Radix Puerariae 100; The Radix Astragali 100; Rhizoma Dioscoreae 100; Fructus Cucurbitae moschatae 100; Fructus Momordicae charantiae 100; Semen Glycines 100; Galla Chinensis 50; Green tea 50; Fire fragrant 50; Ootheca Mantidis 50; Bulbus Allii 50; Radix Glycyrrhizae 50; Pollen 50; Plumula Nelumbinis 50; Cortex Cinnamomi 50 (weight portion).
3, according to the Chinese medicine of claim 1 or 16, the dosage form that it is characterized in that this medicine is any of granule, oral liquid, the agent of bubble bag.