CN1234420C - Sterilizing method for inner surface of inner pipeline of medical instrument - Google Patents
Sterilizing method for inner surface of inner pipeline of medical instrument Download PDFInfo
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- CN1234420C CN1234420C CN 200410073108 CN200410073108A CN1234420C CN 1234420 C CN1234420 C CN 1234420C CN 200410073108 CN200410073108 CN 200410073108 CN 200410073108 A CN200410073108 A CN 200410073108A CN 1234420 C CN1234420 C CN 1234420C
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- pipeline
- water
- sterilizing
- sterilization
- instrument
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- 230000001954 sterilising effect Effects 0.000 title claims abstract description 41
- 238000000034 method Methods 0.000 title claims abstract description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 46
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 38
- 239000003595 mist Substances 0.000 claims abstract description 15
- 238000001035 drying Methods 0.000 claims abstract description 6
- 239000000779 smoke Substances 0.000 claims description 12
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 claims description 9
- 238000002360 preparation method Methods 0.000 claims description 9
- 229910021645 metal ion Inorganic materials 0.000 claims description 8
- 230000008030 elimination Effects 0.000 claims description 3
- 238000003379 elimination reaction Methods 0.000 claims description 3
- 230000015572 biosynthetic process Effects 0.000 claims description 2
- 239000007789 gas Substances 0.000 abstract description 12
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract description 4
- 239000000460 chlorine Substances 0.000 abstract description 4
- 229910052801 chlorine Inorganic materials 0.000 abstract description 4
- 238000004332 deodorization Methods 0.000 abstract description 4
- 238000005516 engineering process Methods 0.000 abstract description 4
- 230000002147 killing effect Effects 0.000 abstract description 3
- 241000894006 Bacteria Species 0.000 abstract description 2
- 241000233866 Fungi Species 0.000 abstract description 2
- 241000191967 Staphylococcus aureus Species 0.000 abstract description 2
- 241000700605 Viruses Species 0.000 abstract description 2
- 230000003444 anaesthetic effect Effects 0.000 abstract description 2
- 239000003344 environmental pollutant Substances 0.000 abstract description 2
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 abstract description 2
- 244000000010 microbial pathogen Species 0.000 abstract description 2
- 231100000719 pollutant Toxicity 0.000 abstract description 2
- 208000028659 discharge Diseases 0.000 abstract 2
- 230000002349 favourable effect Effects 0.000 abstract 2
- 241000304886 Bacilli Species 0.000 abstract 1
- DKWWWNAJHCKBST-UHFFFAOYSA-N [O].CC(O)=O Chemical compound [O].CC(O)=O DKWWWNAJHCKBST-UHFFFAOYSA-N 0.000 abstract 1
- 210000001072 colon Anatomy 0.000 abstract 1
- 238000001631 haemodialysis Methods 0.000 abstract 1
- 230000000322 hemodialysis Effects 0.000 abstract 1
- 208000005252 hepatitis A Diseases 0.000 abstract 1
- 208000002672 hepatitis B Diseases 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 230000010355 oscillation Effects 0.000 abstract 1
- 238000009827 uniform distribution Methods 0.000 abstract 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 7
- 230000000694 effects Effects 0.000 description 5
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 3
- 230000000844 anti-bacterial effect Effects 0.000 description 3
- 230000005684 electric field Effects 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- 206010020741 Hyperpyrexia Diseases 0.000 description 2
- LSDPWZHWYPCBBB-UHFFFAOYSA-N Methanethiol Chemical compound SC LSDPWZHWYPCBBB-UHFFFAOYSA-N 0.000 description 2
- 238000000889 atomisation Methods 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 239000000645 desinfectant Substances 0.000 description 2
- WQOXQRCZOLPYPM-UHFFFAOYSA-N dimethyl disulfide Chemical compound CSSC WQOXQRCZOLPYPM-UHFFFAOYSA-N 0.000 description 2
- QMMFVYPAHWMCMS-UHFFFAOYSA-N dimethyl monosulfide Natural products CSC QMMFVYPAHWMCMS-UHFFFAOYSA-N 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- QEWYKACRFQMRMB-UHFFFAOYSA-N fluoroacetic acid Chemical compound OC(=O)CF QEWYKACRFQMRMB-UHFFFAOYSA-N 0.000 description 2
- 238000003958 fumigation Methods 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 238000002604 ultrasonography Methods 0.000 description 2
- 206010011409 Cross infection Diseases 0.000 description 1
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 206010029803 Nosocomial infection Diseases 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 239000003708 ampul Substances 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- -1 dimethyl sulfide compound Chemical class 0.000 description 1
- 229910001882 dioxygen Inorganic materials 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 229910000037 hydrogen sulfide Inorganic materials 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000004531 microgranule Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 125000004430 oxygen atom Chemical group O* 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000010453 quartz Substances 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
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- Apparatus For Disinfection Or Sterilisation (AREA)
- Disinfection, Sterilisation Or Deodorisation Of Air (AREA)
Abstract
The present invention discloses a method for sterilizing the inner surfaces of pipes in medical instruments. Ultrasonic oscillation and corona discharge are combined to generate water mist with the O3 concentration of 15 to 20 ppm and the diameter of 1 to 5 micrometers, and the technology of O3 treatment of discharge gas and the axial flow heat exchange drying technology are also adopted to complete sterilization, deodorization, drying and tail gas treatment once. After being dissolved in the water mist, O3 has the advantages of uniform distribution, favorable diffusibility and no dead angle, and O3 is suitable for various pathogenic microorganisms and has a favorable killing function on colon bacilli, salmonellae, staphylococcus aureus, viruses of hepatitis B and hepatitis A, fungi and other micro organisms. The sterilizing effect of O3 is equivalent to that of oxygen acetic acid and is higher than that of formaldehyde, and the sterilizing power of O3 is one time stronger than that of chlorine. The sterilizing speed ratio of O3 is 600 to 3000 times higher than that of chlorine, and bacteria can be killed even in several seconds. After O3 is dissolved in water, the sterilizing power becomes stronger, the sterilizing speed becomes higher, and no residual secondary pollutants harmful to human bodies exist. The method of the present invention is suitable for sterilizing the inner surfaces of pipes in various respirators, anesthetic machines, hemodialysis machines, etc.
Description
Technical field
The present invention relates to the sterilization method of Medical Instruments, particularly a kind of sterilization method of inner surface of inner pipeline of medical instrument.
Background technology
At present, traditional sterilization method mainly contains three kinds of approach: 1) adopt the ultraviolet photochemistry sterilization; 2) use various chemical reagent (comprising iodine tincture, ethanol, oxirane and hydrogen peroxide etc.) sterilization; 3) high pressure hyperpyrexia sterilization.These methods have been used for the sterilization of the various medical spaces of clinical medicine, Medical Instruments, medical supplies and operation process by routine, its safety and reliability are confirmed by secular practice.But in scientific research with also have many instruments clinically, according to the needs of its function, instrument internal is made up of complicated gas or fluid pipeline mostly, and instrument costliness mostly.For the sterilization of this part instrument, as using disinfection by ultraviolet light, its subject matter is that penetration power is little, and Disinfection Effect is poor, and especially the inwall to the instrument internal pipeline produces bactericidal action hardly, does not have the disinfectant effect.If adopt chemical reagent to carry out disinfection, as the formaldehyde fumigation method, the one, troublesome poeration, fumigation time is long, the 2nd, also can be with secondary pollution, human body is had certain harm, and routine is done a formaldehyde and is heavily steamed sterilization, generally needs 8 hours, and the formaldehyde residue can be difficult to clean attached to each corner of instrument, the more important thing is, because the pipeline complexity can not thoroughly be killed the antibacterial of the inwall of instrument internal pipeline.And this part instrument can not adopt high pressure hyperpyrexia sterilization again.More than three kinds of traditional sterilization methods all can not carry out effective thorough disinfection to this quasi-instrument, can influence the test result of this kind equipment for a long time or cause medical cross infection.As clinical various types of respirators and anesthetic machine commonly used, when specifically using to patient, except that outside (comprising corrugated tubing) can carry out the normal cleaning and sterilizing, inner complicated breather line all can not carry out routine disinfection, and this is the indeterminable difficult problem of traditional for many years sterilization method.
Summary of the invention
At defective or the deficiency that above-mentioned prior art exists, the object of the present invention is to provide a kind of sterilization method of inner surface of inner pipeline of medical instrument.
To achieve these goals, method of the present invention adopts O
3Be prepared into O after the atomized water microgranule is tied mutually
3Mist is then with O
3Mist input Medical Instruments internal pipeline system is at high concentration O
3Oxidation under, be directly inputted in the pipeline, the instrument internal pipe surface is carried out disinfection; Comprise the following steps:
1) preparation of atomized water: use supersonic generator, producing diameter is the atomized water of the fine mist of 1 μ m-5 μ m;
2) O
3Preparation: utilize ozonator, obtain the ozone that concentration is 30ppm~40ppm;
3) with the atomized water and the step 2 of step 1) preparation) in the ozone combination of making simultaneously, obtain containing the water smoke of ozone concentration>15ppm;
4) connect the container that 500ml metal ion water is housed of 2 polyphones at the exhaust end of the instrument pipeline that is sterilized;
5) water smoke that will contain ozone is then imported the inlet end of the internal pipeline of Medical Instruments, and makes the O that contains from the pipeline discharge
3The container of metal ion water of tail gas by polyphone, with the O in the tail gas
3Fully enter atmosphere after the dissolving;
6) after sterilization finishes, with axial flow heat exchanger heats air to 40 ℃~50 ℃, the air input instrument interior conduit after will heat then, the water smoke that retains in the elimination pipeline.
The present invention utilizes pure oxygen under the high voltage strong electric field condition, and electronics is quickened back and gas molecule collision, O in 10ns by strong electric field power
2Decompose generation antozone (O), only in tens of nanoseconds, oxygen atom combines with oxygen molecule and forms O
3Reuse ultrasonic atomizatio method becomes water the O of the high concentration of water smoke and the generation of corona method
3The O that mixes back formation>15ppm
3Mist is then directly with O
3Mist input Medical Instruments internal pipeline system keeps O from the tail gas of instrument internal pipe outlet
3Concentration>5ppm can reach the purpose of thorough disinfection.
Description of drawings
Fig. 1 is a flow chart of the present invention.
The specific embodiment
In order clearly to understand the present invention, provide technology path (Fig. 1) below in conjunction with the inventor and be further described.
(1) the atomized water preparation utilizes supersonic generator output high-frequency electrical energy, make bottom of gullet crystal transducer generation ultrasound wave acoustic energy, acoustic energy has shaken the sound passing membrane of atomization tank bottom, act on the water in the atomization tank, the surface tension and the inertia of water are changed, make water become diameter, form the vaporific atomized water of water cloud in 1-5 μ m fine fog.
(2) O
3The parallel plate type ozone generating-device is used in preparation under normal pressure, medical oxygen gas is produced corona discharge generation high concentration O through the effect of alternation high voltage electric field
3Advantage is that volume is little, simple in structure, functional, easy-maintaining.
(3) vent gas treatment is utilized O
3Very easily water-soluble characteristics feed tail gas in the water that contains metal ion of 500ml * 2, will remain O
3Soluble in water, make it reach environmental protection standard (O
3<0.5mg/m
3) the back discharging.
(4) dry with the mode heat drying air of axial flow heat exchanger with heat convection, then dry air (40~50 ℃) is imported the interior conduit of instrument, thereby reached rapid elimination water smoke and exsiccant effect.
The O that (1) and (2) is made simultaneously
3Combine with atomized water, its proportion control is at O
3Concentration is>15ppm, then with O
3The internal pipeline inlet end of mist input Medical Instruments, the container that 500ml metal ion water is housed at 2 polyphones of its exhaust end connection will come out to contain O from the exhaust end of pipeline
3The container of metal ion water of tail gas by polyphone, with the O in the tail gas
3Fully enter atmosphere again after the dissolving.
Sterilization beginning back 2min closes the ultrasonic atomizatio generator earlier, and 5min closes ozonator, continues to be blown into dry air (40~50 ℃ of air themperatures) 3min again, and 10min finishes functions such as sterilization, deodorization and drying altogether.
In implementation process, with O
2Be prepared into high concentration O by parallel plate type (or tubular discharge or utilize quartz ampoule glass or heat resistant glass, pottery, rustless steel etc. lure electric body) ozonator
3Mix (O with water through the water cloud mist that supersonic generator is transformed into
3Concentration>15ppm), connect the inlet end of Medical Instruments, at water smoke and O
3With O
2Enter the Medical Instruments internal pipeline under the common pressure, exhaust end contains O with what internal pipeline came out
3The container that 500ml metal ion water be housed of tail gas by 2 polyphones after enter atmosphere again.Sterilization beginning back 2min closes the ultrasound atomizer generator earlier, closes the parallel plate type ozonator behind the 5min, continues to be blown into to continue to be blown into dry air (40~50 ℃ of air themperatures) 3min more again, and 10min can finish functions such as sterilization, deodorization and drying altogether.
O
3Mist has a wide range of applications in medical domain, and major advantage is aspect the sterilization in instrument pipeline:
(1) the strong the present invention of diffusivity utilizes O3With water smoke mixture, O3Be dissolved in the water smoke, CONCENTRATION DISTRIBUTION is even, has improved O3Bactericidal effect, diffusivity is good, no dead angle.
(2) the strong O of sterilizing power3Mist is wide spectrum, efficient, quick sterilization agent. Its bactericidal effect and fluoroacetic acid are suitable, are better than formaldehyde, and sterilizing power doubles than chlorine, sterilization speed than the fast 600-3000 of chlorine doubly, even killing bacteria in seconds. Work as O3Soluble in water, its sterilizing power is stronger, faster. The carrying out property of disinfection function of general disinfectant, accumulation property, and O3Mist is rapidly, in case O3Smelly concentration reaches certain threshold value, and its sterilization is instantaneous to be finished.
(3) fungicidal spectrum extensively is fit to multiple pathogenic microorganisms, and the multiple-microorganisms such as Escherichia coli, salmonella, staphylococcus aureus and hepatitis a and b virus, fungi are all had good killing action.
(4) the good O of the feature of environmental protection3Half-life in empty G﹠W is 20~35min, and the byproduct after decomposing in water is O2, O when having pollutant to exist3Decomposition rate faster. O3The important advantage of burn-off poison is to the not residual any harmful secondary pollution material of environment, water, air, ice, utensil and food.
(5) the good O of deodorization3Mist can with ammonia, hydrogen sulfide, methyl mercaptan, dimethyl sulfide compound, methyl disulfide etc., chemical reaction can take place with them in ozone, generates material nontoxic, odorless.
(6) economic security O3The mist preparation is to utilize conventional medical O2, water and air, cheap, need not preserve, easy to use, safe and reliable.
Claims (3)
1. the sterilization method of an inner surface of inner pipeline of medical instrument is characterized in that, adopts ozone and atomized water to contain the water smoke of ozone in conjunction with formation to the inner surface of pipeline disinfection; Comprise the following steps:
1) preparation of atomized water: use supersonic generator, producing diameter is the atomized water of the fine mist of 1 μ m-5 μ m;
2) O
3Preparation: utilize ozonator, obtain the O that concentration is 30ppm~40ppm
3
3) with above-mentioned steps 1) atomized water and the step 2 of preparation) in the O that makes simultaneously
3In conjunction with, obtain containing O
3The water smoke of concentration>15ppm;
4) connect the container that 500ml metal ion water is housed of 2 polyphones at the exhaust end of the instrument pipeline that is sterilized;
5) will contain O then
3The inlet end of internal pipeline of water smoke input Medical Instruments, and make from what pipeline was discharged and contain O
3The container of metal ion water of tail gas by polyphone, with the O in the tail gas
3Fully enter atmosphere after the dissolving;
6) after sterilization finished, with axial flow heat exchanger heats air to 40 ℃~50 ℃, the air input instrument interior conduit after will heat then carried out drying, the water smoke that retains in the elimination pipeline.
2. the sterilization method of inner surface of inner pipeline of medical instrument as claimed in claim 1 is characterized in that, described pipeline is discharged contains O
3Tail gas in ozone concentration>5ppm.
3. the sterilization method of inner surface of inner pipeline of medical instrument as claimed in claim 1 is characterized in that, described sterilization begins back 2min and closes supersonic generator earlier, closes ozonator through 5min, continues to be blown into dry air 3min again.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410073108 CN1234420C (en) | 2004-09-23 | 2004-09-23 | Sterilizing method for inner surface of inner pipeline of medical instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410073108 CN1234420C (en) | 2004-09-23 | 2004-09-23 | Sterilizing method for inner surface of inner pipeline of medical instrument |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1586628A CN1586628A (en) | 2005-03-02 |
| CN1234420C true CN1234420C (en) | 2006-01-04 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410073108 Expired - Fee Related CN1234420C (en) | 2004-09-23 | 2004-09-23 | Sterilizing method for inner surface of inner pipeline of medical instrument |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1234420C (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101829342B (en) * | 2010-04-26 | 2012-11-21 | 浙江省医疗器械研究所 | Multifunctional disinfecting device |
| CN102062516B (en) * | 2010-11-30 | 2012-05-30 | 贝恩医疗设备(广州)有限公司 | Dryer for dialyzer and dryer for multi-station dialyzer |
| US9358316B2 (en) * | 2011-07-15 | 2016-06-07 | Inceptus, Inc. | Systems, methods and devices for ozone sanitization of continuous positive airway pressure devices |
| DE102014015909B4 (en) | 2014-10-29 | 2020-01-02 | Dräger Safety AG & Co. KGaA | Maintenance device and method for servicing a circulatory breathing apparatus |
| CN106913891A (en) * | 2015-12-24 | 2017-07-04 | 杭州中兵环保股份有限公司 | A kind of food conveyance conduit chlorination equipment and method |
-
2004
- 2004-09-23 CN CN 200410073108 patent/CN1234420C/en not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| CN1586628A (en) | 2005-03-02 |
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