CN1206962C - Inhalation miniature sampling apparatus - Google Patents
Inhalation miniature sampling apparatus Download PDFInfo
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- CN1206962C CN1206962C CN 03117269 CN03117269A CN1206962C CN 1206962 C CN1206962 C CN 1206962C CN 03117269 CN03117269 CN 03117269 CN 03117269 A CN03117269 A CN 03117269A CN 1206962 C CN1206962 C CN 1206962C
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- 238000005070 sampling Methods 0.000 title claims abstract description 58
- 238000007789 sealing Methods 0.000 claims abstract description 29
- 230000008520 organization Effects 0.000 claims 1
- 239000007788 liquid Substances 0.000 abstract description 5
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract description 4
- 241001465754 Metazoa Species 0.000 abstract description 3
- 238000005265 energy consumption Methods 0.000 abstract description 3
- 239000006187 pill Substances 0.000 abstract description 3
- 230000009747 swallowing Effects 0.000 abstract 1
- 230000007704 transition Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 description 5
- 238000010586 diagram Methods 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000010618 wire wrap Methods 0.000 description 1
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Abstract
Description
技术领域:Technical field:
本发明涉及一种可吞入采样装置,特别涉及到一种药丸式的可吞入采样装置,用于在动物或人体的消化道内采集液体。The invention relates to a swallowable sampling device, in particular to a pill type swallowable sampling device for collecting liquid in the digestive tract of animals or human bodies.
背景技术:Background technique:
美国专利US 5395366公开了一种药丸式采样装置,包括一个用于储存采样液体的采样仓、一个用于产生局部真空的活塞、一个用于驱动活塞运动的弹簧、一个用于控制活塞运动的控制机构,该装置用于在动物消化道采集液体。该装置利用压缩弹簧的能量驱动活塞,活塞从采样仓具有单通阀的一端向另一端运动,在运动时产生的局部真空将装置外的液体吸入采样仓。该装置存在以下不足。首先,所述装置最大的缺点是结构复杂。由于该装置利用活塞的运动产生局部真空来采样,活塞在向一端运动时,必须排出气体,因此在所述装置中特别设计了一个排气孔,该排气孔用一可脱离的塞子堵住,在采样时,活塞利用空气压力将塞子挤出,在动作进行时,如果塞子不能脱离,则无法进行采样,可靠性降低。另外,利用弹簧的推力使活塞运动,为了克服摩擦力及空气排出等,需要较大的动力才能驱动,控制能量大的驱动机构相应需要消耗更多的能量来控制,所述装置的控制机构需要较大的电流来控制,增加能量的同时也增加了控制机构的体积。U.S. Patent No. 5,395,366 discloses a pill type sampling device, which includes a sampling chamber for storing sampling liquid, a piston for generating a partial vacuum, a spring for driving the piston, and a control for controlling the movement of the piston. Mechanism, the device is used to collect fluid in the digestive tract of animals. The device uses the energy of the compressed spring to drive the piston, and the piston moves from one end of the sampling chamber with a one-way valve to the other end, and the partial vacuum generated during the movement sucks the liquid outside the device into the sampling chamber. There are following deficiencies in this device. First of all, the biggest disadvantage of the device is its complex structure. Since the device uses the movement of the piston to generate a partial vacuum for sampling, the piston must exhaust gas when it moves to one end, so a vent hole is specially designed in the device, and the vent hole is blocked with a detachable plug , When sampling, the piston uses air pressure to squeeze out the plug. If the plug cannot be disengaged during the operation, sampling cannot be performed, and the reliability is reduced. In addition, the thrust of the spring is used to make the piston move. In order to overcome the friction force and air discharge, etc., it needs a large power to drive, and the drive mechanism with large control energy needs to consume more energy to control. The control mechanism of the device needs Larger current is used to control, while increasing energy, it also increases the volume of the control mechanism.
发明内容:Invention content:
本发明的目的是克服现有技术的不足,提供一种采样可靠性高、能量消耗低、结构简单的吸入式微型采样装置。The purpose of the present invention is to overcome the deficiencies of the prior art and provide a suction micro-sampling device with high sampling reliability, low energy consumption and simple structure.
本发明的技术方案是该装置包括外壳、控制机构、动力机构和可移动机构;外壳由采样端壳体与排气端壳体密封连接构成,外壳的排气端上有与外壳空腔连通的孔,可移动机构与该连通外壳空腔的孔相对,尖锐物固定在可移动机构上,外壳的另一端即采样端具有采样通孔;在可移动机构运动前,可移动机构与控制机构固定连接;在外壳的空腔内装有气囊,在气囊的进气端有与气囊连通且伸出气囊的开口孔,该开口孔内有密封塞,气囊内装有控制机构后,与外壳的内壁过渡配合,在控制机构的孔内装有动力机构和可移动机构,在控制机构上另外设有通孔与控制机构两边的气囊连通,在外壳的采样端有使采样通孔打开或者密闭的机构。The technical scheme of the present invention is that the device includes a casing, a control mechanism, a power mechanism and a movable mechanism; hole, the movable mechanism is opposite to the hole connecting the shell cavity, the sharp object is fixed on the movable mechanism, and the other end of the shell, namely the sampling end, has a sampling through hole; before the movable mechanism moves, the movable mechanism and the control mechanism are fixed Connection; an airbag is installed in the cavity of the shell, and there is an opening hole connected with the airbag and extending out of the airbag at the air intake end of the airbag. There is a sealing plug in the opening hole. After the control mechanism is installed in the airbag, it is transitionally matched with the inner wall of the shell. A power mechanism and a movable mechanism are installed in the hole of the control mechanism, and a through hole is provided on the control mechanism to communicate with the airbags on both sides of the control mechanism, and a mechanism for opening or sealing the sampling through hole is provided at the sampling end of the shell.
本发明的工作过程如下;对气囊完全充气后,该装置被吞入消化道,控制机构在接收到开始采样的控制信号以后,断掉可移动机构与控制机构之间的固定连接,动力机构驱动可移动机构运动,固定在可移动机构上的尖锐物刺破气囊,气囊中的空气迅速从排气端的通孔中排出,气囊迅速收缩,位于采样仓一端的气囊的迅速收缩产生局部真空,位于装置外的液体被吸入到采样仓中。The working process of the present invention is as follows: after the air bag is fully inflated, the device is swallowed into the digestive tract, and the control mechanism breaks the fixed connection between the movable mechanism and the control mechanism after receiving the control signal to start sampling, and the power mechanism drives The movable mechanism moves, and the sharp object fixed on the movable mechanism punctures the airbag, the air in the airbag is quickly discharged from the through hole at the exhaust end, the airbag shrinks rapidly, and the rapid shrinkage of the airbag at one end of the sampling chamber generates a partial vacuum, which is located at Liquid outside the device is drawn into the sampling chamber.
本发明与现有技术相比,具有以下技术效果:Compared with the prior art, the present invention has the following technical effects:
1、采样可靠性高。由于气囊从被刺破处排出气体,该气体直接从通孔排出,不存在通气孔不能被打开的问题,可靠性得到提高。1. High sampling reliability. Because the airbag discharges gas from the punctured part, the gas is directly discharged from the through hole, so there is no problem that the vent hole cannot be opened, and the reliability is improved.
2、能量消耗低。刺破气囊所需要的动力远远小于驱动活塞所需要的动力,相对应的控制机构所需要的能量也相应减少。2. Low energy consumption. The power needed to puncture the airbag is far less than the power needed to drive the piston, and the energy required by the corresponding control mechanism is also correspondingly reduced.
3、结构简单。由于利用气囊的收缩来代替活塞的运动,可以避免复杂的活塞机构设计,省略了弹簧、活塞、密封环等元件,使得结构更加简单。3. Simple structure. Since the contraction of the airbag is used to replace the movement of the piston, the complicated design of the piston mechanism can be avoided, and components such as springs, pistons, and sealing rings are omitted, making the structure simpler.
附图说明Description of drawings
图1是本发明的结构图;Fig. 1 is a structural diagram of the present invention;
图2是本发明的在采样过程中的结构图;Fig. 2 is the structural diagram in sampling process of the present invention;
图3是本发明的采样完成后的结构图;Fig. 3 is the structural diagram after sampling of the present invention is completed;
在图1至图3中:In Figures 1 to 3:
1-外壳,2-气囊,3-控制机构,4-密封塞,5-排气通孔,6-采样仓1-shell, 2-airbag, 3-control mechanism, 4-sealing plug, 5-exhaust through hole, 6-sampling chamber
7-弹簧,8-可熔断线,9-发热电阻,10-圆通孔,11-柔性连接线7-spring, 8-fusible wire, 9-heating resistor, 10-round through hole, 11-flexible connecting wire
12-密封盖,13-支撑弹簧,14-采样通孔,15-尖锐物,16-排气仓,17-可移动机构12-sealing cover, 13-support spring, 14-sampling through hole, 15-sharp object, 16-exhaust chamber, 17-movable mechanism
具体实施方式Detailed ways
本实用新型的外壳由两段密封连接而成,控制机构包括发热电阻[9]、电源及遥控机构,其中电源可以为钮扣电池或者为体外无线电源传输,遥控机构可以采用遥控开关或者采用体外无线传输的电流直接触发的方式,关于体外无线电源传输的具体方法可以参考美国专利US 2002055734。The shell of the utility model is formed by two sections of sealed connection, and the control mechanism includes a heating resistor [9], a power supply and a remote control mechanism, wherein the power supply can be a button battery or an external wireless power transmission, and the remote control mechanism can use a remote control switch or an external For the method of direct triggering of the wirelessly transmitted current, please refer to the US patent US 2002055734 for the specific method of in vitro wireless power transmission.
在控制机构[3]的孔内装有弹簧[7]和可移动机构[17],在可移动机构[17]运动前,可移动机构[17]与控制机构[3]通过可熔断线[8]固定连接在发热电阻[9]上。活塞式的控制机构[3]中另设有圆通孔[10],圆通孔[10]与控制机构[3]两边的气囊连通。气囊[2]中装入控制机构[3]后与外壳[1]的内壁过渡配合,将外壳[1]的内壁所构成的封闭空腔隔离为两个小室,一端为采样仓[6],另一端为排气仓[16]。Spring [7] and movable mechanism [17] are housed in the hole of control mechanism [3]. Before movable mechanism [17] moves, movable mechanism [17] and control mechanism [3] pass fusible link [8 ] is fixedly connected to the heating resistor [9]. In the control mechanism [3] of piston type, be provided with circular through hole [10] in addition, and circular through hole [10] is communicated with the air bag on both sides of control mechanism [3]. After the control mechanism [3] is installed in the airbag [2], it transitionally cooperates with the inner wall of the shell [1] to isolate the closed cavity formed by the inner wall of the shell [1] into two small chambers, one end is a sampling chamber [6], The other end is an exhaust chamber [16].
在气囊的进气端有与气囊连通且伸出气囊的圆形开口孔,该开口孔内有密封塞[4],该气囊[2]的圆形开口孔与位于其中的密封塞[4]通过绕线或者其他方式密封。气囊[2]为柔软高弹性材料制造,在装配时,可以通过注射器从密封塞[4]处注入气体到气囊[2]中,在注入气体后,该气囊处于弹性膨胀状态,位于采样仓[6]端的气囊[2]完全膨胀直到将整个采样仓[6]充满并堵住采样通孔[14]。At the inlet end of the airbag, there is a circular opening that communicates with the airbag and extends out of the airbag. There is a sealing plug [4] in the opening, and the circular opening of the airbag [2] is connected with the sealing plug [4] located therein. Sealed by wire wrap or other means. The airbag [2] is made of soft and high-elastic material. During assembly, gas can be injected into the airbag [2] from the sealing plug [4] through a syringe. After the gas is injected, the airbag is in an elastic expansion state and is located in the sampling chamber [ The air bag [2] at the end of 6] is fully inflated until the whole sampling chamber [6] is filled and the sampling through hole [14] is blocked.
外壳的采样端的使采样通孔打开或者密闭的机构包括密封盖[12]、支撑弹簧[13],支撑弹簧[13]的一端与密封盖固定连接,其另一端位于采样端的通孔内,密封盖[12]与气囊通过柔性连接线[11]固定连接。The mechanism for opening or sealing the sampling through hole of the sampling end of the shell includes a sealing cover [12] and a supporting spring [13]. One end of the supporting spring [13] is fixedly connected with the sealing cover, and the other end is located in the through hole of the sampling end, and the sealing Cover [12] is fixedly connected with air bag by flexible connection line [11].
外壳的采样端的使采样通孔打开或者密闭的机构构包括弹簧、与弹簧固定连接且与采样端通孔配合的密封塞,该与采样端通孔配合的密封塞通过柔性连接线与气囊固定连接。The mechanism for opening or closing the sampling hole at the sampling end of the casing includes a spring, a sealing plug that is fixedly connected with the spring and is matched with the through hole of the sampling end, and the sealing plug that is matched with the through hole of the sampling end is fixedly connected with the air bag through a flexible connection line .
在未受外力作用时,支撑弹簧[13]支撑所述密封盖[12]或者密封塞使得采样通孔[14]处于打开状态,当气囊[2]被刺破后,该柔性连接线[11]在气囊[2]的收缩力的作用下被拉紧,密封盖或者密封塞将采样通孔[14]封闭。When no external force is applied, the supporting spring [13] supports the sealing cover [12] or the sealing plug so that the sampling through hole [14] is in an open state. When the air bag [2] is punctured, the flexible connecting line [11 ] is tensioned under the contraction force of the airbag [2], and the sealing cover or sealing plug seals the sampling through hole [14].
Claims (3)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03117269 CN1206962C (en) | 2003-01-28 | 2003-01-28 | Inhalation miniature sampling apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03117269 CN1206962C (en) | 2003-01-28 | 2003-01-28 | Inhalation miniature sampling apparatus |
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| Publication Number | Publication Date |
|---|---|
| CN1454571A CN1454571A (en) | 2003-11-12 |
| CN1206962C true CN1206962C (en) | 2005-06-22 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 03117269 Expired - Fee Related CN1206962C (en) | 2003-01-28 | 2003-01-28 | Inhalation miniature sampling apparatus |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201304738D0 (en) | 2013-03-15 | 2013-05-01 | Mars Inc | Sampling Device |
| CA2961127C (en) | 2014-09-17 | 2023-07-25 | Mars, Incorporated | Sampling device with ejecting compartment |
| RU2719939C2 (en) * | 2014-09-17 | 2020-04-23 | Марс, Инкорпорейтед | Apparatus |
| WO2016042302A1 (en) | 2014-09-17 | 2016-03-24 | Mars, Incorporated | Device |
| CN108956206A (en) * | 2018-06-15 | 2018-12-07 | 安翰光电技术(武汉)有限公司 | Sampling system based on needle tubing and vacuum technique |
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2003
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| CN1454571A (en) | 2003-11-12 |
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