CN1299818A - Tea flavone as one flavone compound from tea - Google Patents
Tea flavone as one flavone compound from tea Download PDFInfo
- Publication number
- CN1299818A CN1299818A CN00104568A CN00104568A CN1299818A CN 1299818 A CN1299818 A CN 1299818A CN 00104568 A CN00104568 A CN 00104568A CN 00104568 A CN00104568 A CN 00104568A CN 1299818 A CN1299818 A CN 1299818A
- Authority
- CN
- China
- Prior art keywords
- tea
- flavones
- production technique
- teas
- ecg
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229930003944 flavone Natural products 0.000 title claims description 19
- 235000011949 flavones Nutrition 0.000 title claims description 19
- -1 flavone compound Chemical class 0.000 title claims description 5
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 title description 4
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 title description 4
- 150000002212 flavone derivatives Chemical class 0.000 title description 2
- 241001122767 Theaceae Species 0.000 title 1
- 235000013616 tea Nutrition 0.000 claims abstract description 30
- 244000269722 Thea sinensis Species 0.000 claims abstract description 28
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 claims abstract description 18
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 claims abstract description 17
- ADRVNXBAWSRFAJ-UHFFFAOYSA-N catechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3ccc(O)c(O)c3 ADRVNXBAWSRFAJ-UHFFFAOYSA-N 0.000 claims abstract description 17
- 235000005487 catechin Nutrition 0.000 claims abstract description 17
- 229950001002 cianidanol Drugs 0.000 claims abstract description 17
- 238000000034 method Methods 0.000 claims abstract description 11
- WMBWREPUVVBILR-WIYYLYMNSA-N (-)-Epigallocatechin-3-o-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=C(O)C=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-WIYYLYMNSA-N 0.000 claims abstract description 9
- 150000002148 esters Chemical class 0.000 claims abstract description 9
- WMBWREPUVVBILR-UHFFFAOYSA-N GCG Natural products C=1C(O)=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-UHFFFAOYSA-N 0.000 claims abstract description 8
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229960001948 caffeine Drugs 0.000 claims abstract description 8
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 claims abstract description 8
- 238000006555 catalytic reaction Methods 0.000 claims abstract description 7
- 238000000605 extraction Methods 0.000 claims abstract description 7
- 235000009569 green tea Nutrition 0.000 claims abstract description 6
- 239000000126 substance Substances 0.000 claims abstract description 6
- 239000007864 aqueous solution Substances 0.000 claims abstract description 4
- 239000000047 product Substances 0.000 claims description 17
- 150000002213 flavones Chemical class 0.000 claims description 15
- 238000004519 manufacturing process Methods 0.000 claims description 10
- 239000000284 extract Substances 0.000 claims description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 7
- 239000000706 filtrate Substances 0.000 claims description 7
- 235000006468 Thea sinensis Nutrition 0.000 claims description 6
- 239000002994 raw material Substances 0.000 claims description 6
- 239000000654 additive Substances 0.000 claims description 4
- 230000000996 additive effect Effects 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 4
- 235000020333 oolong tea Nutrition 0.000 claims description 4
- 230000004223 radioprotective effect Effects 0.000 claims description 4
- 239000000243 solution Substances 0.000 claims description 4
- 230000008030 elimination Effects 0.000 claims description 3
- 238000003379 elimination reaction Methods 0.000 claims description 3
- 239000013049 sediment Substances 0.000 claims description 3
- 238000001291 vacuum drying Methods 0.000 claims description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical class [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 2
- 238000003810 ethyl acetate extraction Methods 0.000 claims description 2
- 239000012266 salt solution Substances 0.000 claims description 2
- 239000002253 acid Substances 0.000 claims 2
- 239000000470 constituent Substances 0.000 claims 1
- 239000000428 dust Substances 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 238000007654 immersion Methods 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 230000000704 physical effect Effects 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 8
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical group OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract description 3
- 235000013361 beverage Nutrition 0.000 abstract description 3
- 239000002904 solvent Substances 0.000 abstract description 3
- 235000013305 food Nutrition 0.000 abstract description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 238000002791 soaking Methods 0.000 abstract 1
- XMOCLSLCDHWDHP-IUODEOHRSA-N epi-Gallocatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC(O)=C(O)C(O)=C1 XMOCLSLCDHWDHP-IUODEOHRSA-N 0.000 description 8
- LSHVYAFMTMFKBA-TZIWHRDSSA-N (-)-epicatechin-3-O-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=CC=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 LSHVYAFMTMFKBA-TZIWHRDSSA-N 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- LSHVYAFMTMFKBA-UHFFFAOYSA-N ECG Natural products C=1C=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 LSHVYAFMTMFKBA-UHFFFAOYSA-N 0.000 description 4
- XMOCLSLCDHWDHP-UHFFFAOYSA-N L-Epigallocatechin Natural products OC1CC2=C(O)C=C(O)C=C2OC1C1=CC(O)=C(O)C(O)=C1 XMOCLSLCDHWDHP-UHFFFAOYSA-N 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- DZYNKLUGCOSVKS-UHFFFAOYSA-N epigallocatechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3cc(O)c(O)c(O)c3 DZYNKLUGCOSVKS-UHFFFAOYSA-N 0.000 description 4
- PFTAWBLQPZVEMU-UKRRQHHQSA-N (-)-epicatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-UKRRQHHQSA-N 0.000 description 3
- 239000003963 antioxidant agent Substances 0.000 description 3
- 230000003078 antioxidant effect Effects 0.000 description 3
- 235000006708 antioxidants Nutrition 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 208000024172 Cardiovascular disease Diseases 0.000 description 2
- 230000000259 anti-tumor effect Effects 0.000 description 2
- 235000020279 black tea Nutrition 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- HIXDQWDOVZUNNA-UHFFFAOYSA-N 2-(3,4-dimethoxyphenyl)-5-hydroxy-7-methoxychromen-4-one Chemical compound C=1C(OC)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=C(OC)C(OC)=C1 HIXDQWDOVZUNNA-UHFFFAOYSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 1
- 239000003929 acidic solution Substances 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000002155 anti-virotic effect Effects 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 235000021149 fatty food Nutrition 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 230000020477 pH reduction Effects 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 229940034610 toothpaste Drugs 0.000 description 1
- 239000000606 toothpaste Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The technological process for extracting compound "tea-flavone" from green tea or olong tea includes the following steps: soaking, recovering solvent, extracting tea-polyphenol, catalytic reaction and extraction. The obtained product uses ester type catechin (EGCG, ECG) as its main component, and its content can be up to above 90% (removing caffeine). As compared with existent tea-polyphenol it possesses strongs resistance to oxidation, better stability and higher product purity, and can be dissolved in solvents of water, alcohol, methyl alcohol and ethyl ether, and its aqueous solution is yellow-orange colour. It possesses extensive application fields of beverage, medicine, health-care product, food, chemical and radiation-proofing articles.
Description
The invention belongs to a kind of Measurement for Biochemistry of extracting plant effective active composition.
Continuous development along with science and technology, people to the research of tealeaves from previously to the requirement of tea leaf quality, be that color, shape have been developed into from biochemical angle the main component of tealeaves and content are carried out profound research, and developed have anti-oxidant, antitumor, prevent and treat a series of products of functions such as cardiovascular disorder, as tea polysaccharide, tea-polyphenol, catechin (as EGCG, EGC, ECG, EC) etc.One nine six zero years, the Britain biochemist has found the double focusing thing-theoflavin of the catechin that anti-oxidant function is stronger from black tea, but because the content of theoflavin in black tea very low (0.5-1.8%), extraction cost is too high, and theoflavin itself is unstable, therefore, except the standard substance that theoflavin is arranged are sold, but never come out with the form of product.The tea-polyphenol that has formed industrialization is the mixture that catechin and other polyphenolic compound are formed, and its catechin is formed complicated, and the ester catechin relative content is low, and less than 40%, therefore, the medicines and health protection effect of tea-polyphenol is undesirable.Simultaneously, too strong and be easy to produce brown stain because of the bitter taste (being convergency) of tea-polyphenol, be restricted in the application of beverage, healthcare products, medicine and other fields, only in fatty foods, use at present as antioxidant.The monomeric substance of catechin, as NVP-XAA 723 (EGCG), L-Epicatechin gallate (ECG), epigallocatechin (EGC), l-Epicatechol (EC), catechin (C) etc., because the not high and unstable chemcial property of the content of monomer whose in tea-polyphenol, thereby the separation and purification cost is very high, and its product never has extensive industrialization.In a word, the industrialization development in the biochemical field of tealeaves both at home and abroad rests on the tea-polyphenol stage always, and therefore, seeking low-cost high-load stable catechin production technique of extraction and product has become the direction that the tealeaves Biochemical Research is made great efforts.
Show through preliminary search, also from green tea or oolong tea, do not extract the production technique and the product appearance of high-load, that chemical property is stable teas flavonoid substance-ester catechin in the market by acidification reaction.
Purpose of the present invention will be a raw material with green tea or oolong tea exactly, on the basis of tea-polyphenol production technique, tea-polyphenol is carried out catalyzed reaction, thereby produces a kind of compound-teas flavones (being called for short the tea flavones) of new component.
The production technique that the present invention adopts, with low-grade green tea or oolong tea is raw material, and with alcohol-pickled about two hours, recovery of alcohol distillation got medicinal extract, brew medicinal extract with unsaturated salt solution again, the elimination sediment gets filtrate, again filtrate is adjusted to acidic solution, and carries out catalyzed reaction about 2 hours, then with ethyl acetate extraction three times, remove caffeine,, promptly get product at last with extraction liquid vacuum-drying.
The product that this technology that the present invention adopts obtains is to be the teas flavones of main component with the ester catechin, the content of ester catechin can reach more than 90% and (remove caffeine), the main the following aspects of its medicines and health protection effect: anti-ageing, control cardiovascular and cerebrovascular diseases, antitumor, reducing blood-fat, hypoglycemic, anti-bacteria and anti-virus, radioprotective etc.Stability, oxidation-resistance and the ester catechin content of the teas flavones that this technology is extracted are much higher than tea-polyphenol.This technical matters is simple, less investment, and cost is low, and product has purity height, soluble in water, alcohol, methyl alcohol, ether equal solvent, and the aqueous solution shows characteristics such as stable Huang-orange-yellow.The teas flavones that this technology is extracted is because of its distinctive stability, have wide practical use in fields such as beverage, medicine, healthcare products, food, daily-use chemical industry, radioprotective articles for use, as: can be used as the raw material of functional pure tea beverages, the pure product that can be made into Medicines and Health Product capsule, ester catechin can be used as a class medicine or two class medicines, what also can be used as foodstuff additive, makeup and toothpaste protects tooth additive and radioprotective articles for use etc.Become a new milestone in the biochemical development field of tealeaves.
Embodiment: take by weighing the green tea end of 200g, the alcohol 1000ml with 80% soaked 2 hours, crossed the filtering tea grounds and got filtrate 800ml, and concentrated recovered alcohol gets medicinal extract 100ml.In medicinal extract, add 10% Nacl solution 150ml, remove sediment and get filtrate 200ml.Transferring the pH value of filtrate is 4, and 60 degrees centigrade of following catalyzed reactions of temperature 2 hours.Reaction solution extracts three times with 1: 1 ethyl acetate, gets extraction liquid 500ml and removes caffeine.At last that the extraction liquid of gained is dry in vacuum drying oven, promptly get product-teas flavones.Detect through high performance liquid chromatography (HPLC), the composition of the tea flavones product that this technology is extracted is that EGCG content is that 40-68%, ECG content are 14-24% (looking the degree of removing caffeine), content of caffeine is 0.5-26%, that is: the content of " EGCG+ECG+Cafeine " and greater than 85%, other components are: EGC content is that 0.5-3.5%, theoflavin content are 0.5-1.0% or the like.
Claims (8)
1, a kind of is the teas chromocor compound (being called for short the tea flavones) that principal constituent is formed by ester catechin, its production technique feature is: with green tea or oolong tea is that raw material (can be a tea dust, low-grade tea such as tea fragment), after the alcohol-pickled 1.5-3 of 70%-90% hour, the elimination tea grounds, filtrate vacuum concentration recovered alcohol.Gained medicinal extract pours unsaturated common salt aqueous solution, the elimination sediment, and it is acid 1-6.5 that gained filtrate is transferred pH value, carries out under 35-75 ℃ catalyzed reaction 1.5-2.5 hour.Reacted solution is removed caffeine with after 1: 1 the ethyl acetate extraction three times.The vacuum-drying extraction liquid gets product " tea flavones ".
2, teas chromocor compound according to claim 1, wherein two kinds of major ingredient are respectively ester catechin EGCG and ECG, its chemical formula is respectively C
22H
18O
11, C
22H
18O
10, molecular weight is respectively 458 and 442.Its ester catechin is that EGCG is 40-68% at whole tea flavones product proportion, and ECG is 14-24%.Content of caffeine 0.5-26%, that is: the content of " EGCG+ECG+Cafeine " and greater than 85%, all the other several small component content are between 0.1-4.5%.
3, teas chromocor compound according to claim 1, its purposes can be made foodstuff additive, functional pure tea beverages raw material, pharmaceutical raw material, healthcare products, makeup, protect tooth articles for use additive and radioprotective articles for use etc.
4, tea flavones production technique according to claim 1, the ethanol concn that its immersion tealeaves is used is 75-85%, the alcohol consumption is 2-8 a times of tea.
5, tea flavones production technique according to claim 1, the concentration of its used unsaturation salt solution is 1-30%, addition is 0.5-2.5 a times of medicinal extract.
6, tea flavones production technique according to claim 1, its described catalyzed reaction solution acid number is controlled at pH value between 2～4.
7, teas flavones production technique according to claim 1, its catalyzed reaction temperature is 40-60 ℃.
8, tea flavones production technique according to claim 1, the product physical properties is:
Solid is buff powder, and that the aqueous solution is is stable, bright Huang-orange-yellow.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00104568A CN1299818A (en) | 1999-07-23 | 2000-03-23 | Tea flavone as one flavone compound from tea |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN99110586.9 | 1999-07-23 | ||
| CN99110586 | 1999-07-23 | ||
| CN00104568A CN1299818A (en) | 1999-07-23 | 2000-03-23 | Tea flavone as one flavone compound from tea |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1299818A true CN1299818A (en) | 2001-06-20 |
Family
ID=25739245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN00104568A Pending CN1299818A (en) | 1999-07-23 | 2000-03-23 | Tea flavone as one flavone compound from tea |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1299818A (en) |
Cited By (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006071712A1 (en) | 2004-12-23 | 2006-07-06 | Colgate-Palmolive Company | Oral compositions containing oxidized camellia |
| CN101015311B (en) * | 2006-02-08 | 2010-04-21 | 福建省医学科学研究所 | Novel dosage form manufacturing technique of oolong tea molecule microcapsule |
| CN1889847B (en) * | 2003-12-02 | 2010-05-05 | 花王株式会社 | Containerized Beverages |
| CN101019586B (en) * | 2006-02-14 | 2012-09-05 | 株式会社伊藤园 | Beverage |
| CN102933569A (en) * | 2009-12-17 | 2013-02-13 | 新加坡国立大学 | Method of preparing derivatives/oligomers of epicatechin and applications thereof |
| CN103183615A (en) * | 2011-12-29 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Extraction method of honeysuckle chlorogenic acid and its product |
| CN103181877A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Whitening capsules |
| CN103181447A (en) * | 2011-12-29 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Coffee product |
| CN103181430A (en) * | 2011-12-31 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Fresh-keeping tea containing ester catechins-tea flavones, and manufacturing method thereof |
| CN103181943A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Honeysuckle flower oil enteric-coated capsules |
| CN103182056A (en) * | 2011-12-31 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Preparation method of zedoary oil |
| CN103181449A (en) * | 2011-12-29 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | A kind of manufacturing method of health-care chocolate |
| CN103182002A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Composition comprising camellia pollen |
| CN103181948A (en) * | 2011-12-29 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Making method of eucommia leaf extract microcapsule and health care product made from the same |
| CN103181508A (en) * | 2011-12-29 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Pine pollen health care product |
| CN103181516A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Effervescent sugar tablets |
| CN103181554A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Antibacterial and antiviral pearl powder health-care product |
| CN103181450A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Health-care milk candy |
| CN103182001A (en) * | 2011-12-29 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Microencapsulated high-ester type catechin-tea flavonoid crystal and its making method |
| CN103181937A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Antibacterial and antiviral sandalwood oil enteric-coated capsules |
| CN103181878A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Whitening paste composition |
| CN103181451A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Low-energy hard candy |
| CN103181509A (en) * | 2011-12-29 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Microencapsulated Eucommia pollen and its making method |
| CN103191068A (en) * | 2012-01-08 | 2013-07-10 | 新昌县冠阳技术开发有限公司 | Catechin lozenge and its making method |
| CN103190514A (en) * | 2012-01-09 | 2013-07-10 | 新昌县冠阳技术开发有限公司 | Healthcare chocolate |
| CN103190513A (en) * | 2012-01-08 | 2013-07-10 | 新昌县冠阳技术开发有限公司 | Coffee partner product |
| CN103181449B (en) * | 2011-12-29 | 2016-11-30 | 新昌县冠阳技术开发有限公司 | Method for preparing health chocolate |
-
2000
- 2000-03-23 CN CN00104568A patent/CN1299818A/en active Pending
Cited By (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1889847B (en) * | 2003-12-02 | 2010-05-05 | 花王株式会社 | Containerized Beverages |
| US8491945B2 (en) | 2004-12-23 | 2013-07-23 | Colgate-Palmolive Company | Oral compositions containing oxidized Camellia |
| US8137713B2 (en) | 2004-12-23 | 2012-03-20 | Colgate-Palmolive Company | Oral composition containing oxidized Camellia |
| CN101123936B (en) * | 2004-12-23 | 2012-07-18 | 高露洁-棕榄公司 | Oral compositions containing oxidized camellia |
| WO2006071712A1 (en) | 2004-12-23 | 2006-07-06 | Colgate-Palmolive Company | Oral compositions containing oxidized camellia |
| CN101015311B (en) * | 2006-02-08 | 2010-04-21 | 福建省医学科学研究所 | Novel dosage form manufacturing technique of oolong tea molecule microcapsule |
| CN101019586B (en) * | 2006-02-14 | 2012-09-05 | 株式会社伊藤园 | Beverage |
| CN102933569A (en) * | 2009-12-17 | 2013-02-13 | 新加坡国立大学 | Method of preparing derivatives/oligomers of epicatechin and applications thereof |
| CN103183615B (en) * | 2011-12-29 | 2016-05-11 | 新昌县冠阳技术开发有限公司 | A kind of extracting method of honeysuckle chlorogenic acid and goods thereof |
| CN103181449B (en) * | 2011-12-29 | 2016-11-30 | 新昌县冠阳技术开发有限公司 | Method for preparing health chocolate |
| CN103181509B (en) * | 2011-12-29 | 2015-11-25 | 新昌县冠阳技术开发有限公司 | A kind of microencapsulation eucommia pollen and preparation method thereof |
| CN103181447A (en) * | 2011-12-29 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Coffee product |
| CN103183615A (en) * | 2011-12-29 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Extraction method of honeysuckle chlorogenic acid and its product |
| CN103181449A (en) * | 2011-12-29 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | A kind of manufacturing method of health-care chocolate |
| CN103181509A (en) * | 2011-12-29 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Microencapsulated Eucommia pollen and its making method |
| CN103181948A (en) * | 2011-12-29 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Making method of eucommia leaf extract microcapsule and health care product made from the same |
| CN103181508A (en) * | 2011-12-29 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Pine pollen health care product |
| CN103182001A (en) * | 2011-12-29 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Microencapsulated high-ester type catechin-tea flavonoid crystal and its making method |
| CN103181554A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Antibacterial and antiviral pearl powder health-care product |
| CN103181878B (en) * | 2011-12-30 | 2016-12-14 | 新昌县冠阳技术开发有限公司 | A kind of whitening cream compositions |
| CN103181516A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Effervescent sugar tablets |
| CN103181937A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Antibacterial and antiviral sandalwood oil enteric-coated capsules |
| CN103181878A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Whitening paste composition |
| CN103181451A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Low-energy hard candy |
| CN103182002A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Composition comprising camellia pollen |
| CN103181451B (en) * | 2011-12-30 | 2016-05-11 | 新昌县冠阳技术开发有限公司 | A kind of low-yield hard candy |
| CN103181877A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Whitening capsules |
| CN103181450A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Health-care milk candy |
| CN103181943A (en) * | 2011-12-30 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Honeysuckle flower oil enteric-coated capsules |
| CN103181516B (en) * | 2011-12-30 | 2015-11-25 | 新昌县冠阳技术开发有限公司 | A kind of effervescent sugar-tablet |
| CN103182056A (en) * | 2011-12-31 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Preparation method of zedoary oil |
| CN103181430A (en) * | 2011-12-31 | 2013-07-03 | 新昌县冠阳技术开发有限公司 | Fresh-keeping tea containing ester catechins-tea flavones, and manufacturing method thereof |
| CN103190513A (en) * | 2012-01-08 | 2013-07-10 | 新昌县冠阳技术开发有限公司 | Coffee partner product |
| CN103191068B (en) * | 2012-01-08 | 2016-04-20 | 新昌县冠阳技术开发有限公司 | A kind of catechin buccal tablet and manufacture method thereof |
| CN103191068A (en) * | 2012-01-08 | 2013-07-10 | 新昌县冠阳技术开发有限公司 | Catechin lozenge and its making method |
| CN103190514A (en) * | 2012-01-09 | 2013-07-10 | 新昌县冠阳技术开发有限公司 | Healthcare chocolate |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1299818A (en) | Tea flavone as one flavone compound from tea | |
| US20080113044A1 (en) | Extracts and Methods Comprising Green Tea Species | |
| KR101103040B1 (en) | Sumac extract with increased content of active flavonoid compounds and preparation method thereof | |
| CN106943768A (en) | Tea Polyphenols and its extracting method and application | |
| JP3042907B2 (en) | Preparation method of catechin complex | |
| CN112028865A (en) | Method for extracting and preparing high-content dihydromyricetin from vine tea | |
| CN101514219B (en) | Method for extracting black rice anthocyanins | |
| Luximon‐Ramma et al. | Assessment of the polyphenolic composition of the organic extracts of Mauritian black teas: a potential contributor to their antioxidant functions | |
| CN111643578B (en) | Tea leaf extract, preparation method and composition thereof | |
| CN1317966C (en) | Tea essence for tea food and its preparation method | |
| US20100311675A1 (en) | Novel method for preparing purified extracts of harpagophytum procumbens | |
| CN111557406A (en) | Kudzuvine flower extract rich in pueraria flower isoflavone and preparation method and application thereof | |
| WO2025009748A1 (en) | Antioxidative and anti-inflammatory composition comprising extract of carrot leaf lava seawater as active ingredient | |
| JP2004315476A (en) | Hyaluronidase inhibitor | |
| KR20190057504A (en) | Antioxidative composition having improved stability | |
| KR102098042B1 (en) | Preparation method of Rhus verniciflua extract with increased fiseton content and anti-cancer composition containing the same | |
| CN106632207B (en) | A kind of preparation method of high-purity GCG | |
| KR20220067062A (en) | Extracted composition of Dendropanax morbifera having increased Chlorogenic acid and Rutin, and antioxidant activity and preparation method thereof | |
| KR101853423B1 (en) | Manufacturing method of green tea with reduced caffeine content by using supercritical extraction system | |
| CN113080268A (en) | Purple tea and purple tea extract with antioxidant and/or hypoglycemic activities, and preparation method and application thereof | |
| KR100423241B1 (en) | Method of refining and microcapsuling tea extract | |
| CN116804036B (en) | Hydrolyzable tannin monomer compounds in black tea and their applications | |
| CN102911033A (en) | Method for preparing xanthohumol from European hop spike | |
| KR20200016101A (en) | Method for producing the extracts of natural material using ethyl lactate | |
| KR101752476B1 (en) | A process for purifying procyanidins from extract of Lindera obtusiloba Blume |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |