CN1298730A - Process for preparing 'Qianjin' capsule to treat genopathy - Google Patents
Process for preparing 'Qianjin' capsule to treat genopathy Download PDFInfo
- Publication number
- CN1298730A CN1298730A CN 99115682 CN99115682A CN1298730A CN 1298730 A CN1298730 A CN 1298730A CN 99115682 CN99115682 CN 99115682 CN 99115682 A CN99115682 A CN 99115682A CN 1298730 A CN1298730 A CN 1298730A
- Authority
- CN
- China
- Prior art keywords
- radix
- clear paste
- angelicae sinensis
- extracted
- radix angelicae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002775 capsule Substances 0.000 title abstract description 7
- 238000004519 manufacturing process Methods 0.000 title description 4
- 238000005516 engineering process Methods 0.000 claims abstract description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 11
- 241000756943 Codonopsis Species 0.000 claims abstract description 8
- 239000000706 filtrate Substances 0.000 claims abstract description 8
- 238000012545 processing Methods 0.000 claims abstract description 5
- 239000007921 spray Substances 0.000 claims abstract description 4
- 239000003814 drug Substances 0.000 claims description 21
- 238000000034 method Methods 0.000 claims description 13
- 241000746375 Andrographis Species 0.000 claims description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 238000001914 filtration Methods 0.000 claims description 7
- 229940079593 drug Drugs 0.000 claims description 6
- 230000008569 process Effects 0.000 claims description 6
- 238000005325 percolation Methods 0.000 claims description 3
- 238000010992 reflux Methods 0.000 claims description 3
- 239000000047 product Substances 0.000 claims description 2
- 239000002994 raw material Substances 0.000 abstract description 2
- 235000019441 ethanol Nutrition 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 20
- 230000001684 chronic effect Effects 0.000 description 7
- 241000699670 Mus sp. Species 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 239000012567 medical material Substances 0.000 description 5
- 208000029082 Pelvic Inflammatory Disease Diseases 0.000 description 4
- 239000004480 active ingredient Substances 0.000 description 4
- 206010008323 cervicitis Diseases 0.000 description 4
- 201000003988 chronic cervicitis Diseases 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 210000004291 uterus Anatomy 0.000 description 2
- 241001147468 Chondrus ocellatus Species 0.000 description 1
- CMSMOCZEIVJLDB-UHFFFAOYSA-N Cyclophosphamide Chemical compound ClCCN(CCCl)P1(=O)NCCCO1 CMSMOCZEIVJLDB-UHFFFAOYSA-N 0.000 description 1
- 206010014025 Ear swelling Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 208000004145 Endometritis Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 235000009161 Espostoa lanata Nutrition 0.000 description 1
- 240000001624 Espostoa lanata Species 0.000 description 1
- 206010018691 Granuloma Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000019255 Menstrual disease Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 210000000683 abdominal cavity Anatomy 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- YBHILYKTIRIUTE-UHFFFAOYSA-N berberine Chemical compound C1=C2CC[N+]3=CC4=C(OC)C(OC)=CC=C4C=C3C2=CC2=C1OCO2 YBHILYKTIRIUTE-UHFFFAOYSA-N 0.000 description 1
- 229940093265 berberine Drugs 0.000 description 1
- QISXPYZVZJBNDM-UHFFFAOYSA-N berberine Natural products COc1ccc2C=C3N(Cc2c1OC)C=Cc4cc5OCOc5cc34 QISXPYZVZJBNDM-UHFFFAOYSA-N 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000004856 capillary permeability Effects 0.000 description 1
- 208000030373 chronic endometritis Diseases 0.000 description 1
- 229960004397 cyclophosphamide Drugs 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 238000001647 drug administration Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 238000003809 water extraction Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
A qianjin capsule for treating gynaecopathia is made of euphorbiae lathyridis, radix rosea laevigatae, herba andrographitis, radix angelicae sinensis, caulis mahoniae, caulis spatholobi, and radix codonopsis pilosulae as raw materials, and its processing technology is as follows: use ethyl alcohol to extract radix angelicae sinensis and herba andrographitis to obtain clear paste; decoct euphorbiae lathyridis, radix rosea laevigatea etc to obtain decoction liquid, decoct and filter twice to obtain filtrate, combined and make into clear paste, and finally combine all pastes, mix uniformly and spray dried, then pelletize and fill to obtain capsule.
Description
The present invention relates to a kind of processing technology of FUKE QIANJIN JIAONANG, belong to the manufacturing process class of Chinese medicinal capsule preparation.
China's Chinese medicine generally adopts decoction, pill, powder etc., later on along with tablet has appearred again in society's science and technology, economic progress.FUKE QIANJIN PIAN is to be raw material with very heavy group of Chinese crude drug, Radix Rosae Laevigatae, Herba Andrographis, Radix Angelicae Sinensis, Caulis Mahoniae, Fructus Zanthoxyli Dissiti, Caulis Spatholobi and Radix Codonopsis, through the tablet form compound Chinese patent medicine of selecting materials, pulverizing, operation such as granulation, Bao Qian being made.Clinical practice through has for many years shown that it is a kind of a kind of good medicine that is applicable to gynaecopathias such as woman uterus inflammation, urgent chronic pelvic inflammatory disease, endometritis, menoxenia, leucorrhoea grow in quantity really.
The Chinese patent medicine FUKE QIANJIN PIAN is a kind of rare gynecological's good medicine, but it still exists some weakness of Chinese patent medicine tablet: dose is bigger, will eat 6 at every turn; Patient is when taking this tablet, though eaten into the effective ingredient that it works the effect of curing the disease, the adjuvant of in fact also having eaten into fiber such as quite a few plant roots that contains these medicine active ingredients, stem, leaf and invalid element simultaneously and having added in production process.And patient is after taking medicine, and some effective ingredient can not fully be digested and assimilated and excrete thereupon by the intestines and stomach; Patient is after taking medicine, and tablet disintegration time under one's belt is long, it is slow or the like to take effect.So how to improve the bioavailability of Chinese medicine, active ingredient is fully extracted, improving curative effect of medication is the developing direction of Chinese patent medicine, capsule then is one of its correct selection path.
Purpose of the present invention aims to provide the requirement of a kind of adaptation FUKE QIANJIN PIAN compatibility, can make the FUKE QIANJIN JIAONANG production technology of its performance optimum curative effect.
This is the FUKE QIANJIN JIAONANG of compatibility by very heavy group of Chinese crude drug, Radix Rosae Laevigatae, Herba Andrographis, Radix Angelicae Sinensis, Caulis Mahoniae, Fructus Zanthoxyli Dissiti, Caulis Spatholobi and Radix Codonopsis, and its processing technology is:
A, at first Radix Angelicae Sinensis is extracted with alcohol percolation method make clear paste;
B, Herba Andrographis extracted with ethanol refluxing process make clear paste;
C, Caulis Mahoniae, Fructus Zanthoxyli Dissiti decocting in water are extracted twice, after filtering the merging of both filtrates is made clear paste;
D, very heavy group, Radix Rosae Laevigatae, Caulis Spatholobi, Radix Codonopsis decocting in water are extracted an after-filtration, the medicinal residues after the filter with the Radix Angelicae Sinensis medicinal residues of technology A and the Herba Andrographis medicinal residues decocting in water of technology B, are filtered, merging filtrate is also made clear paste;
E, merge above-mentioned A, B, four kinds of clear paste of C, D, through mixing-spray drying-granulation-fill four procedures the finished product FUKE QIANJIN JIAONANG.
According to the FUKE QIANJIN JIAONANG that above-mentioned process program is produced, to compare with the FUKE QIANJIN PIAN that has circulated at present the city, its advantage is to make the active ingredient extraction in the medical material more abundant, the relative enrichment of active ingredient; Simultaneously medicine disintegration time under one's belt shortens, and has eliminated former mixing and has contained the invalid thing in the Herba Andrographis and Radix Angelicae Sinensis in the FUKE QIANJIN PIAN, and patient's drug administration amount is reduced, and improves the curative effect instant effect.
Below provide embodiment, and further set forth the present invention in conjunction with the embodiments.
Prescription according to the compound women's QIANJIN PIAN: the incorporation of Radix Angelicae Sinensis, Radix Codonopsis, Herba Andrographis and Fructus Zanthoxyli Dissiti respectively is 9% of a medical material total amount; The incorporation of Radix Rosae Laevigatae, Caulis Spatholobi, Caulis Mahoniae and Radix Flemingiae Philippinensis respectively is 16% of medical material portion amount.Then, at first Radix Angelicae Sinensis is extracted with alcohol percolation method and make clear paste according to above-mentioned process; Secondly Herba Andrographis is extracted with ethanol refluxing process and make clear paste; It three is that Caulis Mahoniae, Fructus Zanthoxyli Dissiti decocting in water are extracted twice, after filtering twice filtrate merging is made clear paste; It four is with very heavy group, Radix Rosae Laevigatae, Caulis Spatholobi, after-filtration of Radix Codonopsis decocting in water, and the medicinal residues after the filter with the Radix Angelicae Sinensis medicinal residues of technology A and the Herba Andrographis medicinal residues decocting in water of technology B, are filtered and merge two filtrates and also make clear paste; Its five be merge above-mentioned four kinds of clear paste, through mixing-spray drying-granulation-fill four procedures FUKE QIANJIN JIAONANG.
In above-mentioned operation, what really play effect is that above-mentioned all medical materials are adopted the method for extracting of handling respectively; Experiment through this programme inventor: adopt the difference decocting in water extracting method of Radix Rosae Laevigatae, very heavy group and Caulis Mahoniae and Fructus Zanthoxyli Dissiti, than decocting in water extraction that above-mentioned four kinds of medical materials are mixed, the content of tannin and berberine exceeds 2.5～5 times respectively in its filtrate.
Zoopery is the result show: FUKE QIANJIN JIAONANG all has the obvious suppression effect to rat paw edema due to Oleum Tiglii induced mice ear swelling, the chondrus ocellatus Holmes and rat cotton balls granuloma.The scorching card of rat uterus also there is good inhibitory action, and the effect of capsule sheet is better than the tablet FUKE QIANJIN JIAONANG can resist the capillary permeability increase effect of acetic acid induced mice abdominal cavity, to the tangible blood tonification effect of type blood deficiency mice tool of losing blood, can also resist the immune function of mice reduction that cyclophosphamide causes.Extracorporeal bacteria inhibitor test is the result show: to 9 kinds of antibacterials such as escherichia coli the clinical separation of totally 95 strains cause bacterium certain bacteriostasis arranged.To the coli-infection mice, high dose has the certain protection effect, and the capsule effect slightly is better than tablet.
The clinical application observe the curative effect is as follows:
Through No. 1 Hospital Affiliated to Hunan Traditional Chinese Medical College, Hunan Province woman keep healthy institute, Hunan Province Affiliated Hospital of the academy of traditional Chinese medicine from March, 1998～1998 year November to 381 routine women's chronic pelvic inflammatory diseases, chronic endometritis, chronic cervicitis patient, adopt FUKE QIANJIN PIAN, FUKE QIANJIN JIAONANG, three kinds of medicines of JINJI PIAN to treat, test group (FUKE QIANJIN JIAONANG group) 161 examples wherein, matched group (FUKE QIANJIN PIAN group) 100 examples; Chronic palace intimitis 60 examples, wherein each 30 example of test group (FUKE QIANJIN JIAONANG group) and matched group (FUKE QIANJIN PIAN group); Chronic cervicitis 60 examples, wherein each 30 example of test group (FUKE QIANJIN JIAONANG group) and matched group (FUKE QIANJIN PIAN group).And with state of an illness integrated value judgement curative effect before and after the treatment.
The result shows: the total obvious effective rate of (1) FUKE QIANJIN JIAONANG treatment chronic pelvic inflammatory disease, total effective rate are respectively 80.12%, 98.75%; Treat the total obvious effective rate of chronic palace intimitis, total effective rate is respectively 100%, 100%; The total obvious effective rate of treatment chronic cervicitis, total effective rate are respectively 33.3%, 96.7%; Its determined curative effect is better than FUKE QIANJIN PIAN sheet group; The medicine of (2) two kinds of dosage forms all has the effect of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, benefiting qi and nourishing blood, strong waist and nourishing kidney, chronic pelvic inflammatory disease, chronic palace intimitis, chronic cervicitis patient all there is better curative effect, (3) FUKE QIANJIN JIAONANG is lacked than the QIANJIN PIAN consumption, it is more convenient to take medicine, and welcome by patient and clinician; (4) FUKE QIANJIN JIAONANG drug safety is not seen toxic and side effects and untoward reaction in the observation process.
Clinical application shows: FUKE QIANJIN PIAN and FUKE QIANJIN JIAONANG curative effect obviously are better than JINJI PIAN, and the FUKE QIANJIN JIAONANG curative effect is better than FUKE QIANJIN PIAN: really reach final goal of the present invention.
Claims (1)
1, a kind of is the FUKE QIANJIN JIAONANG of compatibility by very heavy group of Chinese crude drug, Radix Rosae Laevigatae, Herba Andrographis, Radix Angelicae Sinensis, Caulis Mahoniae, Fructus Zanthoxyli Dissiti, Caulis Spatholobi and Radix Codonopsis, and its processing technology is:
A, at first Radix Angelicae Sinensis is extracted with alcohol percolation method make clear paste;
B, Herba Andrographis extracted with ethanol refluxing process make clear paste;
C, Caulis Mahoniae, Fructus Zanthoxyli Dissiti decocting in water are extracted twice, after filtering the merging of both filtrates is made clear paste;
D, very heavy group, Radix Rosae Laevigatae, Caulis Spatholobi, Radix Codonopsis decocting in water are extracted an after-filtration, the medicinal residues after filtering with the Radix Angelicae Sinensis medicinal residues of technology A and the Herba Andrographis medicinal residues decocting in water of technology B, are filtered, merging filtrate is also made clear paste;
E, merge above-mentioned A, B, four kinds of clear paste of C, D, through mixing-spray drying-granulation-fill four procedures the finished product FUKE QIANJIN JIAONANG.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB99115682XA CN1170549C (en) | 1999-12-07 | 1999-12-07 | Process for preparing 'Qianjin' capsule to treat genopathy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB99115682XA CN1170549C (en) | 1999-12-07 | 1999-12-07 | Process for preparing 'Qianjin' capsule to treat genopathy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1298730A true CN1298730A (en) | 2001-06-13 |
| CN1170549C CN1170549C (en) | 2004-10-13 |
Family
ID=5278607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB99115682XA Expired - Lifetime CN1170549C (en) | 1999-12-07 | 1999-12-07 | Process for preparing 'Qianjin' capsule to treat genopathy |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1170549C (en) |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1318054C (en) * | 2004-08-26 | 2007-05-30 | 仁和（集团）发展有限公司 | Prepn process of medicine for treating gynecopathy |
| CN1330335C (en) * | 2004-06-18 | 2007-08-08 | 株洲千金药业股份有限公司 | Method for preparing a gynecopathy treating medicine |
| CN101347496B (en) * | 2007-07-20 | 2011-10-05 | 天津天士力制药股份有限公司 | Effective component of Spatholobus stem and preparation and use thereof |
| CN102552740A (en) * | 2012-01-06 | 2012-07-11 | 刘梅 | Chinese medicine for curing gynecological inflammations and preparation method thereof |
| CN102973739A (en) * | 2012-12-06 | 2013-03-20 | 青岛文创科技有限公司 | Traditional Chinese medicine composition for treating gynaecology chronic pelvic inflammatory disease |
| CN105012753A (en) * | 2015-08-07 | 2015-11-04 | 张卉 | Traditional Chinese medicine for treating acute endometritis and preparation method |
| CN109091567A (en) * | 2018-11-14 | 2018-12-28 | 株洲千金药业股份有限公司 | Application of the volatile oil part of gynaecology's prescriptions worth thousand gold or gynaecology's prescriptions worth thousand gold in preparation treatment fibroid drug |
| CN109172677A (en) * | 2018-11-14 | 2019-01-11 | 株洲千金药业股份有限公司 | ' Qianjin ' capsule to treat ganopathy and preparation method thereof |
| CN109254098A (en) * | 2018-11-14 | 2019-01-22 | 株洲千金药业股份有限公司 | A kind of method of quality control of ' Qianjin ' capsule to treat ganopathy |
| CN109364147A (en) * | 2018-11-14 | 2019-02-22 | 株洲千金药业股份有限公司 | A kind of ' Qianjin ' capsule to treat ganopathy and preparation method thereof |
| CN109568206A (en) * | 2018-12-26 | 2019-04-05 | 株洲千金药业股份有限公司 | A kind of bacteria inhibiting composition being exclusively used in women and washing lotion and preparation method |
| CN109722931A (en) * | 2017-10-31 | 2019-05-07 | 株洲千金药业股份有限公司 | A kind of go to the lavatory towel and its method of the preparation of prescriptions worth thousand gold dregs of a decoction resource regeneration |
| WO2020098831A1 (en) * | 2018-11-14 | 2020-05-22 | 株洲千金药业股份有限公司 | Gynecological qianjin capsule and quality control method therefor |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN100408070C (en) * | 2005-04-14 | 2008-08-06 | 广西灵峰药业有限公司 | A kind of medicine for treating gynecological inflammation and its production method |
| WO2017157260A1 (en) | 2016-03-17 | 2017-09-21 | 株洲千金药业股份有限公司 | Phenylpropanoid and preparation method and application thereof |
-
1999
- 1999-12-07 CN CNB99115682XA patent/CN1170549C/en not_active Expired - Lifetime
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1330335C (en) * | 2004-06-18 | 2007-08-08 | 株洲千金药业股份有限公司 | Method for preparing a gynecopathy treating medicine |
| CN1318054C (en) * | 2004-08-26 | 2007-05-30 | 仁和（集团）发展有限公司 | Prepn process of medicine for treating gynecopathy |
| CN101347496B (en) * | 2007-07-20 | 2011-10-05 | 天津天士力制药股份有限公司 | Effective component of Spatholobus stem and preparation and use thereof |
| CN102552740A (en) * | 2012-01-06 | 2012-07-11 | 刘梅 | Chinese medicine for curing gynecological inflammations and preparation method thereof |
| CN102973739A (en) * | 2012-12-06 | 2013-03-20 | 青岛文创科技有限公司 | Traditional Chinese medicine composition for treating gynaecology chronic pelvic inflammatory disease |
| CN105012753A (en) * | 2015-08-07 | 2015-11-04 | 张卉 | Traditional Chinese medicine for treating acute endometritis and preparation method |
| CN109722931A (en) * | 2017-10-31 | 2019-05-07 | 株洲千金药业股份有限公司 | A kind of go to the lavatory towel and its method of the preparation of prescriptions worth thousand gold dregs of a decoction resource regeneration |
| CN109091567A (en) * | 2018-11-14 | 2018-12-28 | 株洲千金药业股份有限公司 | Application of the volatile oil part of gynaecology's prescriptions worth thousand gold or gynaecology's prescriptions worth thousand gold in preparation treatment fibroid drug |
| CN109254098A (en) * | 2018-11-14 | 2019-01-22 | 株洲千金药业股份有限公司 | A kind of method of quality control of ' Qianjin ' capsule to treat ganopathy |
| CN109364147A (en) * | 2018-11-14 | 2019-02-22 | 株洲千金药业股份有限公司 | A kind of ' Qianjin ' capsule to treat ganopathy and preparation method thereof |
| CN109172677A (en) * | 2018-11-14 | 2019-01-11 | 株洲千金药业股份有限公司 | ' Qianjin ' capsule to treat ganopathy and preparation method thereof |
| WO2020098831A1 (en) * | 2018-11-14 | 2020-05-22 | 株洲千金药业股份有限公司 | Gynecological qianjin capsule and quality control method therefor |
| US12144841B2 (en) | 2018-11-14 | 2024-11-19 | Qianjin Pharmaceutical Co., Ltd. | Fuke Qianjin Capsule and quality control method therefor |
| CN109568206A (en) * | 2018-12-26 | 2019-04-05 | 株洲千金药业股份有限公司 | A kind of bacteria inhibiting composition being exclusively used in women and washing lotion and preparation method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1170549C (en) | 2004-10-13 |
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