CN1295962C - Micro-emulsion of phenyl ether methyl cyclic-azole - Google Patents

Abstract

The invention discloses a difenoconazole microemulsion, which comprises the following composition: 3-20% of difenoconazole, 5-12% of solvent oil, 5-15% of emulsifier, 5-15% of solubilizer, antifreeze 3% to 7% of the agent, and the balance is water, wherein, each composition is a percentage by weight. The invention has good medicinal effects on pear scab, apple spot defoliation, tomato early blight, watermelon blight, capsicum anthracnose and strawberry powdery mildew, and the control effect reaches more than 86%. In addition, since no organic solvent is used, not only the manufacturing cost is low, but also the toxicity of the formulation to users is reduced. The invention has no peculiar smell and is nonflammable, so it is relatively safe during transportation and storage.

Description

Difenoconazole microemulsion

technical field

The invention relates to a broad-spectrum fungicide.

Background technique

Pear scab, apple leaf spot, tomato early blight, watermelon blight, pepper anthracnose and strawberry powdery mildew are common fruit and vegetable diseases, and difenoconazole is usually used to deal with these diseases. However, there are still several problems as follows: 1, emulsifiable concentrate (organic solvent) is usually used as a solvent during use, which not only leads to high cost, but also is unfavorable for the performance of the drug; 2, due to the long use time, it is necessary to increase the metering 3. In addition, due to long-term use, the above-mentioned diseases have developed serious drug resistance to difenoconazole, resulting in poor or even ineffective control effects.

Contents of the invention

In view of the above existing problems, the purpose of the present invention is to provide a difenoconazole microemulsion with better disease prevention effect, which not only has low toxicity, but also saves a large amount of organic solvents and reduces production costs.

In order to achieve the above object, a difenoconazole microemulsion of the present invention comprises the following composition: 3-20% of difenoconazole, 5-12% of solvent naphtha, 5-15% of emulsifier, and 5-15% of solubilizer , 3% to 7% of antifreeze, and the balance is water, wherein each composition is a percentage by weight, and the solvent oil can be selected from xylene, ethanol, propanol, butanol, ethyl acetate, acetohexanone, and acetone. One, the emulsifier can be selected from non-ionic surfactant or anionic surfactant, and the non-ionic surfactant is phenyl biphenol polyvinyl ether, phenylethylphenol polyoxyethylene ether, phenylethylphenol Polyoxyethylene polyoxypropylene ether, nonylphenol polyoxyethylene ether, alkylphenol polyoxyethylene ether formaldehyde condensate, etc., the anionic surfactant is sodium alkylbenzenesulfonate, C ₈ -C ₂₀ alkane Sodium base sulfate, styrene polyvinyl nitrogen ether sulfate.

Further, the preferred composition is: 5% difenoconazole, 7% mineral spirits, 10% emulsifier, 10% solubilizer, 5% antifreeze, and the balance is water, wherein each composition is weight percent.

Further, the solubilizer can be selected from one of cycloethanol, acetohexanone and dichloromethane.

Further, the antifreezing agent can be selected from one of ethylene glycol, propylene glycol, glycerol, polyethylene glycol, and sorbitol.

The invention has very good medicinal effects on pear scab, apple spot defoliation, tomato early blight, watermelon blight, capsicum anthracnose and strawberry powdery mildew, and the control effect reaches more than 86%. In addition, since no organic solvent is used, not only the manufacturing cost is low, but also the toxicity of the formulation to users is reduced. The invention has no peculiar smell and is nonflammable, so it is relatively safe during transportation and storage.

Detailed ways

The molecular formula of difenoconazole is C ₁₉ H ₁₇ C ₁₂ N ₃ O ₃ , the appearance is off-white powder, the density is 1.40g/cm ³ (20°C), the melting point is 78.6°C, and the vapor pressure is 3.3×10 ^-8 Pa ( 25°C), solubility (25°C) water 15mg/L, ethanol 330g/L, acetone 610g/L, toluene 490g/L, n-hexane 3.4g/L, n-zinc alcohol 95g/L. The appearance of the preparation is rice to brown fine grains, the density is 0.3-0.5g/cm ³ , and the pH is 7.0-11.0.

Example 1

Weigh 3% difenoconazole, 12% xylene, 15% phenyl biphenol polyvinyl ether, 8% cycloethanol, 8% ethylene glycol, and 54% water according to weight percentage; Azole, xylene, phenyl biphenol polyvinyl ether, cycloethanol and ethylene glycol are fully mixed, and at the same time, slowly add water while stirring until the stirring is uniform and the water is added completely.

When in use, dilute it with water at a ratio of 1:1000-1500, spray it, and spray it 1-2 times.

Example 2

Take by weighing 20% of difenoconazole, 6% of ethanol, 8% of sodium alkylbenzene sulfonate, 8% of acehexanone, 6% of propylene glycol, and 52% of water; , Sodium Alkylbenzene Sulfonate, Acetohexanone and Propylene Glycol are fully mixed, and at the same time, slowly add water while stirring, until the stirring is uniform and the water is added completely.

When in use, dilute it with water at a ratio of 1:1000-1500, spray it, and spray it 1-2 times.

Example 3

Take by weight 5% difenoconazole, 7% propanol, 10% phenethylphenol polyoxyethylene ether, 10% dichloromethane, 5% glycerol, and 63% water; Meconazole, propanol, phenethylphenol polyoxyethylene ether, methylene chloride and glycerol are fully mixed, and at the same time, water is slowly added while stirring until the stirring is uniform and the water is completely added.

When in use, dilute it with water at a ratio of 1:1000-1500, spray it, and spray it 1-2 times.

Claims (4)

1. A difenoconazole microemulsion, characterized in that it comprises the following composition: 3-20% of difenoconazole, 5-12% of solvent naphtha, 5-15% of emulsifier, and 5-15% of solubilizer , 3% to 7% of antifreeze, and the balance is water, wherein each composition is a percentage by weight, and the solvent oil can be selected from xylene, ethanol, propanol, butanol, ethyl acetate, acetohexanone, and acetone. One, the emulsifier can be selected from non-ionic surfactant or anionic surfactant, and the non-ionic surfactant is phenyl biphenol polyvinyl ether, phenylethylphenol polyoxyethylene ether, phenylethylphenol Polyoxyethylene polyoxypropylene ether, nonylphenol polyoxyethylene ether, alkylphenol polyoxyethylene ether formaldehyde condensate, the anionic surfactant is sodium alkylbenzenesulfonate, C ₈ -C ₂₀ alkyl Sodium Sulfate, Styrene Polyvinyl Ether Sulfate. 2. A difenoconazole microemulsion according to claim 1, characterized in that the preferred composition is: 5% difenoconazole, 7% solvent naphtha, 10% emulsifier, and 10% solubilizer , antifreeze 5%, the balance is water, wherein, each composition is weight percent. 3. A difenoconazole microemulsion according to claim 1 or 2, characterized in that the solubilizer can be selected from cycloethanol, acetohexanone and dichloromethane. 4. A difenoconazole microemulsion according to claim 3, wherein the antifreezing agent can be selected from one of ethylene glycol, propylene glycol, glycerol, polyethylene glycol and sorbitol.