CN1293035A - Acupoint application of nm-material - Google Patents
Acupoint application of nm-material Download PDFInfo
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- CN1293035A CN1293035A CN 99116983 CN99116983A CN1293035A CN 1293035 A CN1293035 A CN 1293035A CN 99116983 CN99116983 CN 99116983 CN 99116983 A CN99116983 A CN 99116983A CN 1293035 A CN1293035 A CN 1293035A
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- nano
- colloid
- soft base
- nanometer
- base material
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- 239000000463 material Substances 0.000 title claims abstract description 89
- 239000000084 colloidal system Substances 0.000 claims abstract description 49
- 239000003814 drug Substances 0.000 claims abstract description 26
- 239000006247 magnetic powder Substances 0.000 claims abstract description 24
- 239000002086 nanomaterial Substances 0.000 claims description 41
- 239000000945 filler Substances 0.000 claims description 24
- 229910010293 ceramic material Inorganic materials 0.000 claims description 20
- 229940079593 drug Drugs 0.000 claims description 10
- 238000002156 mixing Methods 0.000 claims description 6
- 238000000465 moulding Methods 0.000 claims description 6
- 239000000843 powder Substances 0.000 abstract description 10
- 230000000694 effects Effects 0.000 abstract description 5
- 239000000919 ceramic Substances 0.000 abstract description 3
- 239000011573 trace mineral Substances 0.000 abstract description 2
- 235000013619 trace mineral Nutrition 0.000 abstract description 2
- 239000000203 mixture Substances 0.000 abstract 1
- 239000011505 plaster Substances 0.000 description 6
- 239000002674 ointment Substances 0.000 description 3
- 239000004709 Chlorinated polyethylene Substances 0.000 description 2
- NKANXQFJJICGDU-QPLCGJKRSA-N Tamoxifen Chemical compound C=1C=CC=CC=1C(/CC)=C(C=1C=CC(OCCN(C)C)=CC=1)/C1=CC=CC=C1 NKANXQFJJICGDU-QPLCGJKRSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 230000005291 magnetic effect Effects 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 239000010409 thin film Substances 0.000 description 2
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 description 1
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N Alumina Chemical compound [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- GJSURZIOUXUGAL-UHFFFAOYSA-N Clonidine Chemical compound ClC1=CC=CC(Cl)=C1NC1=NCCN1 GJSURZIOUXUGAL-UHFFFAOYSA-N 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- MQIUGAXCHLFZKX-UHFFFAOYSA-N Di-n-octyl phthalate Natural products CCCCCCCCOC(=O)C1=CC=CC=C1C(=O)OCCCCCCCC MQIUGAXCHLFZKX-UHFFFAOYSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 239000004593 Epoxy Substances 0.000 description 1
- MKXZASYAUGDDCJ-SZMVWBNQSA-N LSM-2525 Chemical compound C1CCC[C@H]2[C@@]3([H])N(C)CC[C@]21C1=CC(OC)=CC=C1C3 MKXZASYAUGDDCJ-SZMVWBNQSA-N 0.000 description 1
- 239000004820 Pressure-sensitive adhesive Substances 0.000 description 1
- 229910004298 SiO 2 Inorganic materials 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 125000005396 acrylic acid ester group Chemical group 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000005030 aluminium foil Substances 0.000 description 1
- AGXUVMPSUKZYDT-UHFFFAOYSA-L barium(2+);octadecanoate Chemical compound [Ba+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O AGXUVMPSUKZYDT-UHFFFAOYSA-L 0.000 description 1
- BJQHLKABXJIVAM-UHFFFAOYSA-N bis(2-ethylhexyl) phthalate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)OCC(CC)CCCC BJQHLKABXJIVAM-UHFFFAOYSA-N 0.000 description 1
- 229940025250 camphora Drugs 0.000 description 1
- 239000010238 camphora Substances 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 229960002896 clonidine Drugs 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 229960001985 dextromethorphan Drugs 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- PJMPHNIQZUBGLI-UHFFFAOYSA-N fentanyl Chemical compound C=1C=CC=CC=1N(C(=O)CC)C(CC1)CCN1CCC1=CC=CC=C1 PJMPHNIQZUBGLI-UHFFFAOYSA-N 0.000 description 1
- 229960002428 fentanyl Drugs 0.000 description 1
- 239000003302 ferromagnetic material Substances 0.000 description 1
- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 description 1
- 239000000395 magnesium oxide Substances 0.000 description 1
- AXZKOIWUVFPNLO-UHFFFAOYSA-N magnesium;oxygen(2-) Chemical compound [O-2].[Mg+2] AXZKOIWUVFPNLO-UHFFFAOYSA-N 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 230000005476 size effect Effects 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 229960001603 tamoxifen Drugs 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
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- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A nm-material for dressing acupoint for medical and health-care purposes is disclosed. Said nm-class material can be contained in soft base material and/or colloid and may be nm-class magnetic powder, infrared ceramic powder, medicine powder, or trace elements, or their mixture. It features high effect.
Description
The present invention is a kind of point application with health care, medical function, particularly a kind of point application that contains nanometer materials.
The nano material that the present invention relates to is an important component part of nanosecond science and technology.Material reaches the nanometer scale scope, will the special nature that block materials is different from molecularity again occur being different from.As quantum size effect, skin effect etc.Existing various point application no matter be that magnetic oozes ointment, still contains the plaster of far infrared, does not contain nanometer materials in its soft base material and the colloid.Application number is that 98100260.9 Chinese patent application discloses a kind of " infrared pain relieving plaster ".It comprises: layer of cloth, be coated in the medical acrylic acid esters pressure-sensitive adhesive coating that is mixed with SiO 2 powder, aluminium sesquioxide powder on the cloth, skin is a silicone oil paper.This particles of powder size is between the 80-200 order, and big like this granule is placed in the colloid, is applied on the skin of human body, and the people is felt very ill; Simultaneously, infrared transmitance is very low, and the unit radiance is very low, to the health care or the also reduction greatly of therapeutical effect of human body.The patent No. is that 93104192.9 Chinese patent discloses a kind of " multi-functional medical paster and preparation method thereof ".This medical paster is made up of the thin film and the paster of band adhesive.Contain 2～50% ceramic powder, 10～80% spice in the thin film; Contain magnetic powder of 50～90% etc. in the paster.That application number is that 92113415.0 Chinese patent application discloses is a kind of " far infrared emitting material and contain Chinese medicine far infrared plaster ", and it is that the far infrared ray radiation powder material is added some Chinese medicines, and reuse viscosity base material is made and contained Chinese medicine far infrared plaster.In above-mentioned two kinds of technical schemes,, comparatively speaking, bad to absorption of human body because the medicated powder body or the magnetic powder that contain in applying ointment or plaster do not contain nanometer materials; The Chinese medicine powder medicine can not effectively spread, and makes the release that the active ingredient of medicine can not maximum; Some medicine or plant extraction liquid can not be dissolved in colloid mutually; Particularly for some medicine and base material and colloid chemical reaction can take place, in case merge mutually, can influence the effect of medicine.At present also in point application, do not use nanometer materials.
The purpose of this invention is to provide a kind of point application that contains nanometer materials,
The object of the present invention is achieved like this.Acupoint application of nm-material includes soft base material 2, colloid 3, and colloid is laminated with on the one side of soft base material; Also include nano material in applying ointment or plaster.
Nano material can be contained in separately in the soft base material, also can be contained in separately in the colloid, also can be contained in simultaneously in soft base material and the colloid.Include figuration material and filler in the soft base material, the figuration material can account for the 5-90% of soft base material gross weight.Filler can all be a nano material, and nano material and the molding of figuration material mixing form the nanometer soft base material.Filler can a part be a nano material also, and other is a filler; Nano material and filler, the molding of figuration material mixing form the nanometer soft base material.
Nano material can be nano-magnetic powder in the soft base material, and nano-magnetic powder can account for 5～95% of filler and nano-magnetic powder gross weight; Also can be the nanometer infrared ceramic material; The nanometer infrared ceramic material accounts for 5～20% of filler and nanometer infrared ceramic material gross weight; Also can be nano-magnetic powder and nanometer infrared ceramic material; Nano-magnetic powder and nanometer infrared ceramic material account for 5～60% of filler and nano-magnetic powder, nanometer infrared ceramic material gross weight; Nano material also can be Nano medication in the soft base material 2, and Nano medication accounts for 5～20% of filler and Nano medication gross weight.Above-mentioned nano material in the soft base material is combination in any as required also.
Contain nano material in colloid, pressure sensitive colloid can account for the 70-98% of colloid gross weight in the colloid, and all the other are nano material just.Nano material can be the nanometer infrared ceramic material in the colloid; Also can be Nano medication; Also can be nanometer microelement, also it makes up arbitrarily.
Another side at soft base material is a surface-treated layer 1; The another side of pressure sensitive colloid is stained with separate paper 4.
The present invention becomes single domain by multidomain after utilizing ferromagnetic material to enter nanometer scale, has higher coercivity, when particle diameter further reduces, superparamagnetism will occur, and magnetic property is greatly improved.The present invention utilizes nano-ceramic powder, makes the far infrared radiation rate be improved, and greatly improves far transmitance, thereby human body is produced extremely useful effect.Unprecedented high specific surface and surface activity that the present invention utilizes nanoparticle to have are made nanoscale with trace element, make the easier absorption of human body, also easier from soft base material or colloid migration enter subcutis.Utilize flourishing this reason of surface area of Nano medication just, the active ingredient of medicine is more discharged under the unit grammes per square metre, for some medicine and base material or colloid chemical reaction can take place especially, cause in the time of can not merging mutually, adopting nano-grade medicine is fabulous method.The present invention makes treatment, health-care effect highly significant owing to contain nanometer materials.
The present invention is provided by following examples and accompanying drawing thereof.
Accompanying drawing is a structural representation of the present invention.
1 surface-treated layer, 2 soft base materials, 3 colloids, 4 separate papers.
Acupoint application of nm-material, colloid 3 are laminated with on the one side of soft base material 2, and the another side of soft base material forms surface-treated layer 1 with special emulsion paint spraying or with aluminium foil; Colloidal another side is stained with separate paper 4.
In the soft base material, account for 12.5% of soft base material gross weight based on the figuration material of chlorinated polyethylene, other 87.5% or all be nano material, or wherein a part is nano material and filler sum.
The figuration material includes:
Chlorinated polyethylene 10%,
Epoxy soybean oil 0.5%,
Adjacent stupid dioctyl phthalate di-n-octyl 0.3%,
Magnesium oxide 0.6%,
Barium stearate 0.5%,
Silicon 0.6%.
Embodiment 1: the figuration material is the same.Filler all is a nano-magnetic powder.Nano-magnetic powder accounts for 87.5% of soft base material gross weight.Nano-magnetic powder and the molding of figuration material mixing form the nanometer soft base material.Pressure sensitive colloid accounts for 89% of colloid gross weight in the colloid, and all the other are nano material.Nano material is 8% nanometer infrared ceramic material and 3% nano-grade medicine tamoxifen in the colloid.
Embodiment 2: the figuration material is the same.Filler is magnetic powder and nano material.Nano material is a nano-magnetic powder.Filler accounts for 87.5% of soft base material gross weight.Magnetic powder accounts for 80% in the filler, and nano-magnetic powder accounts for 20%.Pressure sensitive colloid accounts for 89% of colloid gross weight in the colloid, and all the other are nano material.Nano material is 3% nano-grade medicine fentanyl and 8% nanometer infrared ceramic material in the colloid.Have the filler and the molding of figuration material mixing of nano-magnetic powder, form the nanometer soft base material.Colloid is laminated with on the one side of soft base material.
Embodiment 3: the figuration material is the same.The figuration material accounts for 15% of soft base material gross weight.Contain magnetic powder in the filler and as the nano ceramic material of nano material, filler accounts for 85% of soft base material gross weight.Magnetic powder accounts for 87% in the filler, and nano ceramic material accounts for 13%.Pressure sensitive colloid accounts for 90% of colloid gross weight in the colloid, and all the other are nano material.Nano material is 3% nano-grade medicine clonidine and 7% Camphora, Borneolum Syntheticum, Herba Menthae, milettia reticulata in the colloid.
Embodiment 4: the figuration material adopts the nanoscale far-infrared ceramic material of 90% medical grade rubber and 10% to constitute soft base material.Pressure sensitive colloid accounts for 96% of colloid gross weight in the colloid, nanometer microelement zinc, copper, germanium 1%; Nano-grade medicine dextromethorphan 3%.
Claims (14)
1, a kind of acupoint application of nm-material includes soft base material 2, colloid 3, and colloid is laminated with on the one side of soft base; Soft base material contains the figuration material, it is characterized in that also including nano material.
2, according to the described acupoint application of nm-material of claim 1, it is characterized in that containing in the soft base material nano material, nano material and the molding of figuration material mixing form the nanometer soft base material.
3,, it is characterized in that containing in the soft base material filler according to the described acupoint application of nm-material of claim 2; Nano material and filler, the molding of figuration material mixing form the nanometer soft base material.
4, according to the acupoint application of nm-material of claim described 2, it is characterized in that containing nano material in the colloid 3, pressure sensitive colloid accounts for the 70-98% of colloid gross weight in the colloid, and all the other are nano material; The another side of soft base material is a surface-treated layer 1; Colloidal another side is stained with separate paper 4.
5, according to claim 1,3 described acupoint application of nm-material, it is characterized in that containing nano material in the colloid 3, pressure sensitive colloid accounts for the 70-98% of colloid gross weight in the colloid, and all the other are nano material.
6, according to the described acupoint application of nm-material of claim 5, the another side that it is characterized in that soft base material is a surface-treated layer 1; Colloidal another side is stained with separate paper 4.
7, according to the described acupoint application of nm-material of claim 6, it is characterized in that nano material is a nano-magnetic powder in the soft base material 2, nano material accounts for 5～95% of filler and nano-magnetic powder gross weight.
8,, it is characterized in that nano material is the nanometer infrared ceramic material in the soft base material 2 according to the described acupoint application of nm-material of claim 6; The nanometer infrared ceramic material accounts for 5～20% of filler and nanometer infrared ceramic material gross weight.
9,, it is characterized in that nano material is nano-magnetic powder and nanometer infrared ceramic material in the soft base material 2 according to the described acupoint application of nm-material of claim 6; Nano-magnetic powder and nanometer infrared ceramic material account for 20～90% of filler and nano-magnetic powder, nanometer infrared ceramic material gross weight.
10, according to the described acupoint application of nm-material of claim 6, it is characterized in that nano material is a Nano medication in the soft base material 2, Nano medication accounts for 5～20% of filler and Nano medication gross weight.
11,, it is characterized in that nano material is the nanometer infrared ceramic material in the colloid according to the described acupoint application of nm-material of claim 6.
12,, it is characterized in that nano material is a Nano medication in the colloid according to the described acupoint application of nm-material of claim 6.
13,, it is characterized in that nano material is a nanometer microelement in the colloid according to the described acupoint application of nm-material of claim 6.
14,, it is characterized in that nano material is nanometer infrared ceramic material, Nano medication and nanometer microelement in the colloid according to the described acupoint application of nm-material of claim 6.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 99116983 CN1293035A (en) | 1999-10-18 | 1999-10-18 | Acupoint application of nm-material |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 99116983 CN1293035A (en) | 1999-10-18 | 1999-10-18 | Acupoint application of nm-material |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1293035A true CN1293035A (en) | 2001-05-02 |
Family
ID=5279635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 99116983 Pending CN1293035A (en) | 1999-10-18 | 1999-10-18 | Acupoint application of nm-material |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1293035A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100431541C (en) * | 2003-06-10 | 2008-11-12 | 帝国制药株式会社 | Fentanyl-containing patch for oral mucosa |
| CN106551755A (en) * | 2016-11-30 | 2017-04-05 | 兰州交通大学 | A kind of magnetic Nano medication patch and preparation method thereof |
-
1999
- 1999-10-18 CN CN 99116983 patent/CN1293035A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100431541C (en) * | 2003-06-10 | 2008-11-12 | 帝国制药株式会社 | Fentanyl-containing patch for oral mucosa |
| CN106551755A (en) * | 2016-11-30 | 2017-04-05 | 兰州交通大学 | A kind of magnetic Nano medication patch and preparation method thereof |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
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