CN1279952C - Medicine for treating burn and scald - Google Patents
Medicine for treating burn and scald Download PDFInfo
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- CN1279952C CN1279952C CN 200310105749 CN200310105749A CN1279952C CN 1279952 C CN1279952 C CN 1279952C CN 200310105749 CN200310105749 CN 200310105749 CN 200310105749 A CN200310105749 A CN 200310105749A CN 1279952 C CN1279952 C CN 1279952C
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Abstract
The invention provides a medicament for treating burns and scalds, which is prepared from Chinese medicinal herbs including alkanna tinctoria, red peony root, flavescent sophora root, raw weeping forsythia, raw phellodendron bark, raw gardenia jasminoides, raw dahurian angelica root, raw licorice root, realgar, borneol, dried alum, raw alum, natural indigo and the like, sesame oil, vaseline and the like as raw materials.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of burn and scald, especially the minerals medicine with Chinese herbal medicine, Chinese medicine is a raw material, is the Chinese patent medicine ointment that basic fat is made with Oleum Sesami, vaseline.
Background technology
The burn and scald that the area that a variety of causes causes and the degree of depth do not wait is the commonly encountered diseases of serious harm human health.That various empyrosis wound surfaces all have is red, swollen, hot, bitterly, easy infection, slow clinical characters heals.Particularly the larger area burn and scald can cause that immune function of human body descends, and vital signs such as shock, septicemia appear in the body metabolism disorder, can cause death when serious.
At present, to the Drug therapy of burn and scald, there are the following problems both at home and abroad:
1, the burn and scald wet treatment of domestic employing employed " moist expose burn ointment ", its heat-clearing and toxic substances removing, putrefaction-removing granulation-promoting effect are not obvious, and easy infection, weak curative effect, the wound surface anti-infection ability is poor, the wound healing phase is long, and healing back wound surface easily causes scar hyperplasia.The wound surface of obstinate, repeated infection has only the skin-grafting of armrest art just can finish healing.
2, domestic and international general burn and scald dry therapy, wound surface uses silver sulfadiazine cold cream or sulfanilamide cold cream, and patient takes a large amount of antibiotic, causes in the body and the wound flora imbalance, and severe infections has been deepened the wound surface degree of depth, the treatment time prolongation.The septicemia that dysbacteriosis causes, pyemia are the main causes of death.The skin-grafting meeting brings serious health misery and financial burden to the patient repeatedly.
3, various homemade burn and scald medicines are gone up by society at present, and curative effect differs, and can not treat the burn and scald of the large tracts of land and the degree of depth, safety, poor reliability.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of medicine for the treatment of burn and scald, to improve the therapeutic effect of burn and scald.
The present invention is achieved in that a kind of medicine for the treatment of burn and scald, and it is the medicament of being made by the following weight proportion raw material
Radix Arnebiae (Radix Lithospermi) 50～150 weight portions
Radix Paeoniae Rubra 50～150 weight portions
Radix Sophorae Flavescentis 30～90 weight portions
Give birth to Fructus Forsythiae 30～90 weight portions
Phellodendron bark 30～90 weight portions
Gardenia 20～60 weight portions
Give birth to the Radix Angelicae Dahuricae 10～30 weight portions
Radix Glycyrrhizae 10～30 weight portions
Realgar 10～20 weight portions
Borneolum Syntheticum 10～20 weight portions
Dry Alumen 8～20 weight portions
Give birth to Alumen 2～8 weight portions
Indigo Naturalis 10～20 weight portions
Colophonium 5～15 weight portions
Sanguis Draxonis 4～10 weight portions
Catechu 5～10 weight portions
Hydrocerussitum (Ceruse) 2～6 weight portions
Oleum Sesami 2500 weight portions
Vaseline 500 weight portions
Use is the result show, a kind of medicine for the treatment of burn and scald of the present invention has following advantage:
1, its adopts plant class, minerals medicine, is basic fat with Oleum Sesami, vaseline, and scientific formulation can be given full play to the drug effect of each raw material, has reduced the toxic and side effects of each crude drug to greatest extent, and is clinical safe and reliable.
2, it has solved the wet treatment of clinical employing and greatest problem---the traumatic infection that dry therapy exists effectively.The present invention's medicine can be accelerated wound healing, shortening edema phase, the phase of oozing out.Treatment time is short, and patient is painful few, can prevent the generation of septicemia effectively, makes the patient reduce unnecessary skin grafting, or for the skin grafting of necessity provides a good surgical condition, improves success rate of operation.When being used for large tracts of land and deep burn, its advantage is more outstanding.
3, use the not good infective wound surface of other drug therapeutic effect, behind use the present invention's the medicine, traumatic infection is a may command, and pus disappears, and wound surface enters the reparation phase.
4, except that burn and scald, the present invention's medicine also is adapted to various wound infections such as other various wounds, surgical wound surface infection.
The specific embodiment
Further specify the present invention below.
The present invention a kind of treats in the medicine of burn and scald, and the weight of each raw material (preferably) proportioning is
Radix Arnebiae (Radix Lithospermi) 50～100 weight portions
Radix Paeoniae Rubra 50～150 weight portions
Radix Sophorae Flavescentis 30～60 weight portions
Give birth to Fructus Forsythiae 30～60 weight portions
Phellodendron bark 30～60 weight portions
Gardenia 20～40 weight portions
Give birth to the Radix Angelicae Dahuricae 10～20 weight portions
Radix Glycyrrhizae 10～20 weight portions
Realgar 10～15 weight portions
Borneolum Syntheticum 10～15 weight portions
Dry Alumen 8～12 weight portions
Give birth to Alumen 2～4 weight portions
Indigo Naturalis 10～15 weight portions
Colophonium 5～8 weight portions
Sanguis Draxonis 4～6 weight portions
Catechu 5～7 weight portions
Hydrocerussitum (Ceruse) 2～4 weight portions
Oleum Sesami 2500 weight portions
Vaseline 500 weight portions
A kind of preparation method of the present invention's medicine is, in the plant medicine thing, take out Radix Arnebiae (Radix Lithospermi) and singly put, and water is moistening stand-by, and other drug mixes disconnected broken; In the minerals medicine, Realgar, Sanguis Draxonis are ground into impalpable powder, cross 100～120 mesh sieves, again it is mixed and be ground into superfine powder with Borneolum Syntheticum, dry Alumen, living Alumen, Indigo Naturalis, Colophonium, catechu, Hydrocerussitum (Ceruse), it is standby to cross 100～120 mesh sieves.After Oleum Sesami put fried material pot internal heating, it was fried to shrivelled to put into the plant medicine thing again, drags for and removes slag, put into the Radix Arnebiae (Radix Lithospermi) after moistening again, low baking temperature is fried to be removed slag, filters to shrivelled, gets aubergine medicine oil, when medicine oil cooling to 130～170 ℃, put into vaseline and fully stirring, when being cooled to 90～110 ℃, put into the minerals medicine that is ground into fine powder, after stirring, promptly can be made into the ointment of the present invention's medicine.After this can inject in the plastic-aluminum pipe and pack.Drop into cold water cooling with the plastic-aluminum pipe summer, winter natural cooling.Putting the shady and cool ventilation place preserves.
The technical scheme of the present invention's medicine is with reference to traditional Chinese medical science therapeutic treatment burn and scald, skin infection, the employed medicine of various wound, research successive dynasties name side, analysis has been used for reference handed down from the older generations of the family number for burn and scald secret recipe and a large amount of effective folk prescription, proved recipes, in conjunction with the pharmacological research of modern treatment burn and scald or fruit and Therapeutic Principle, filter out meticulously have reducing swelling and alleviating pain, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, putrefaction-removing granulation-promoting, the evacuation of pus of drawing out pus by applying a plaster to the affected part, bactericidal effect is good, anti-infection ability is strong, the medicine of promotion wound healing.The minerals medicine that is adopted is a medicine commonly used in the successive dynasties prescription, and the dosage of use is all below oral safe dose.The combination of plant medicine thing and minerals medicine has improved the complementarity between each medicine, makes it have the effect of anti-inflammatory analgetic, clearing away heat and cooling blood, dissipating rashes blood stasis dispelling, heat clearing and damp drying, convergence wound surface, and anti-infection ability improves greatly.Employed medicine medicine source is wide, and the property of medicine is stable, and clinical use has reduced its toxic and side effects to greatest extent.
The ointment of the present invention's medicine (being the ointment that is constrained on it with the consumption of each raw material is example) mineral class content of medicines (content of every 50g finished medicines) is as follows:
| Title | Content mg/50g | Allow one time oral dose (g) |
| Realgar | 172mg | 0.15～0.3 |
| Borneolum Syntheticum | 172mg | 0.15～0.3 |
| Dry Alumen | 137mg | 0.6～1.5 |
| Give birth to Alumen | 34mg | 0.6～1.5 |
| Indigo Naturalis | 172mg | 1.5～3 |
| Colophonium | 86mg | 1.5～3 |
| Sanguis Draxonis | 68mg | 1～3 |
| Catechu | 86mg | 1～3 |
| Hydrocerussitum (Ceruse) | 34mg | 0.6～0.9 |
As can be seen from the above table, the content of the ointment mineral class medicine of the present invention's medicine is all below oral safety line.
The pharmacological effect of the raw material in the present invention's the medicine is:
1, Radix Arnebiae (Radix Lithospermi), clearing away heat and cooling blood, dissipating rashes detoxifcation cure mainly carbuncle eczema, burn.
2, Radix Paeoniae Rubra, dissipating blood stasis blood, detumescence pain, clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.
3, Radix Sophorae Flavescentis, heat clearing and damp drying cures mainly hemorrhoid, malignant boil, burn and scald.
4, give birth to Fructus Forsythiae, heat-clearing and toxic substances removing, mass dissipating and swelling eliminating cure mainly all skin infection.
5, phellodendron bark, eliminating fire and detoxication, treatment of ulcer aphtha, impetigo, burn and scald.
6, Gardenia, cool the blood dissipate blood stasis cures mainly pathopyretic ulcer, swelling and pain due to blood stasis.
7, give birth to the Radix Angelicae Dahuricae, reducing swelling and alleviating pain, the wind damp eliminating of loosing cures mainly ulcer sores, scabies.
8, Radix Glycyrrhizae, coordinating the actions of various ingredients in a prescription is separated the poison of Realgar and Hydrocerussitum (Ceruse), controls wound surface ulcer.
9, Realgar changes blood such as water, detoxifcation parasite killing, cures mainly ulcer sores, herpes zoster.
10, dry Alumen, the convergence wound surface cures mainly that ulcer does not close up for a long time, hemorrhoid, otitis media etc.
11, give birth to Alumen, killing parasites for relieving itching, sterilization are anticorrosion, and treatment of ulcer is suppurated etc.
12, Borneolum Syntheticum, is walked 12 warps at clearing away heat to alleviate pain, cures mainly the ulcer that swells and ache, burn and scald.
13, Indigo Naturalis, heat-clearing and toxic substances removing, removing heat from blood cure mainly aphtha, erysipelas, impetigo, furuncle and phyma.
14, catechu, promoting tissue regeneration by astringents, treatment of ulcer does not close up for a long time, aphtha, wound.
15, Colophonium, the granulation promoting pain relieving cures mainly ulcer sores, traumatic hemorrhage, burn and scald.
16, Sanguis Draxonis, blood circulation promoting and blood stasis dispelling, hemostasis and pain-relieving cure mainly traumatic hemorrhage, skin infection does not close up for a long time.
17, Hydrocerussitum (Ceruse), removing toxic substances and promoting granulation cures mainly ulcer sores, erysipelas, burn and scald.
The using method of the ointment of the present invention's medicine is, when burn and scald takes place, can directly smear this medicine on wound surface, smearing thickness about about 1mm, every day 1～2 time.Dirtier wound surface can be with cold water or clean flushing with clean water wound surface, wipes away and smears this medicine after doing.During large-area burns, directly smear this medicine, can effectively prevent the intrusion of various viruses, antibacterial.It is dry that the treatment characteristics of this medicine are that nature exposes, wound surface in edema, ooze out after date and enter healing stage, at soft subcrustal healing.
It below is clinical observation material.
Be the clinical effectiveness of the Drug therapy burn and scald that shows the present invention, use silver sulfadiazine cold creams and 300 examples to use the case of Ointment in Treatment burn and scald of the present invention's medicine, contrast with 100 examples.
The diagnostic criteria of burn and scald: depth of burn adopts three degree quarterings medically commonly used at present.When burn surface area calculates, press rule of Nine if wound surface is concentrated, wound surface disperses then to use palm test.For improving its comparability, the burn surface area of the case of test group, matched group is 1%～10%, and depth of burn is shallow II degree～dark II degree.Two groups depth of burn and burn surface area are suitable substantially.
The criterion of curative effect: cure, wound surface all heals; Effectively, wound surface dwindles more than 1/3; Invalid, wound surface dwindles below 1/3.
Test group, 300 examples, wherein male 200 examples, women 100 examples at 2～70 years old age, use the ointment of the present invention's medicine to treat.Administrated method is with above-mentioned.
Matched group, 100 examples, wherein male 64 examples, women 36 examples at 2～70 years old age, use the medicine silver sulfadiazine cold cream commonly used of doctor trained in Western medicine to treat.Its administrated method is, smears on wound surface, and smearing thickness is about 1～3mm, every day 1～2 time.
Therapeutic effect sees the following form.
| Group | Total routine number | The routine number (accounting for the % of total routine number) of fully recovering | Routine number (accounting for the % of total routine number) takes a turn for the better | Invalid routine number (accounting for the % of total routine number) | Total effective rate % |
| Matched group | 100 | 21 (21.0％) | 39 (39.0％) | 40 (40.0％) | 60.0％ |
| Test group | 300 | 295 (98.3％) | 4 (1.3％) | 1 (0.3％) | 99.6％ |
As can be seen from the above table, the therapeutic effect of the ointment of the present invention's medicine is better than the medicine silver sulfadiazine cold cream commonly used of doctor trained in Western medicine greatly.
Embodiment 1
Take by weighing raw material by following proportioning:
Radix Arnebiae (Radix Lithospermi) 50g, Radix Paeoniae Rubra 50g, Radix Sophorae Flavescentis 30g gives birth to Fructus Forsythiae 30g, phellodendron bark 30g, Gardenia 20g gives birth to Radix Angelicae Dahuricae 10g, Radix Glycyrrhizae 10g, Realgar 10g, Borneolum Syntheticum 10g, dry Alumen 8g gives birth to Alumen 2g, Indigo Naturalis 10g, Colophonium 5g, Sanguis Draxonis 4g, catechu 5g, Hydrocerussitum (Ceruse) 2g, Oleum Sesami 2500g, vaseline 500g.
In the plant medicine thing, take out Radix Arnebiae (Radix Lithospermi) and singly put, and water to be moistening stand-by, other drug mixes disconnected broken; In minerals medicine kind, Realgar, Sanguis Draxonis are ground into impalpable powder, cross 120 mesh sieves, again with its with Borneolum Syntheticum, dry Alumen, give birth to Alumen, Indigo Naturalis, Colophonium, catechu, Hydrocerussitum (Ceruse) and mix and be ground into superfine powder to cross 120 mesh sieves standby.After Oleum Sesami put fried material pot internal heating, it was fried to shrivelled to put into the plant medicine thing again, drags for and removes slag, put into the Radix Arnebiae (Radix Lithospermi) after moistening again, low baking temperature is fried to be removed slag, filters to shrivelled, gets aubergine medicine oil, when medicine oil cooling to 150 ℃, put into vaseline and fully stirring, when being cooled to 100 ℃, put into the minerals medicine that is ground into fine powder, after stirring, promptly can be made into the ointment of the present invention's medicine.After this can inject in the plastic-aluminum pipe and pack.
Embodiment 2
Press fan's proportioning and take by weighing raw material:
Radix Arnebiae (Radix Lithospermi) 150g, Radix Paeoniae Rubra 100g, Radix Sophorae Flavescentis 90g gives birth to Fructus Forsythiae 30g, phellodendron bark 30g, Gardenia 40g gives birth to Radix Angelicae Dahuricae 20g, Radix Glycyrrhizae 10g, Realgar 15g, Borneolum Syntheticum 15g, dry Alumen 10g gives birth to Alumen 8g, Indigo Naturalis 15g, Colophonium 5g, Sanguis Draxonis 10g, catechu 10g, Hydrocerussitum (Ceruse) 4g, Oleum Sesami 2500g, vaseline 500g.
In the plant medicine thing, take out Radix Arnebiae (Radix Lithospermi) and singly put, and water to be moistening stand-by, other drug mixes disconnected broken; In minerals medicine kind, Realgar, Sanguis Draxonis are ground into impalpable powder, cross 110 mesh sieves, again with its with Borneolum Syntheticum, dry Alumen, give birth to Alumen, Indigo Naturalis, Colophonium, catechu, Hydrocerussitum (Ceruse) and mix and be ground into superfine powder to cross 110 mesh sieves standby.After Oleum Sesami put fried material pot internal heating, it was fried to shrivelled to put into the plant medicine thing again, drags for and removes slag, put into the Radix Arnebiae (Radix Lithospermi) after moistening again, low baking temperature is fried to be removed slag, filters to shrivelled, gets aubergine medicine oil, when medicine oil cooling to 160 ℃, put into vaseline and fully stirring, when being cooled to 110 ℃, put into the minerals medicine that is ground into fine powder, after stirring, promptly can be made into the ointment of the present invention's medicine.After this can inject in the plastic-aluminum pipe and pack.
Embodiment 3
Take by weighing raw material by following proportioning:
Radix Arnebiae (Radix Lithospermi) 100g, Radix Paeoniae Rubra 100g, Radix Sophorae Flavescentis 80g gives birth to Fructus Forsythiae 80g, phellodendron bark 60g, Gardenia 60g gives birth to Radix Angelicae Dahuricae 20g, Radix Glycyrrhizae 20g, Realgar 15g, Borneolum Syntheticum 15g, dry Alumen 15g gives birth to Alumen 5g, Indigo Naturalis 15g, Colophonium 10g, Sanguis Draxonis 8g, catechu 8g, Hydrocerussitum (Ceruse) 4g, Oleum Sesami 2500g, vaseline 500g.
In the plant medicine thing, take out Radix Arnebiae (Radix Lithospermi) and singly put, and water to be moistening stand-by, other drug mixes disconnected broken; In minerals medicine kind, Realgar, Sanguis Draxonis are ground into impalpable powder, cross 120 mesh sieves, again with its with Borneolum Syntheticum, dry Alumen, give birth to Alumen, Indigo Naturalis, Colophonium, catechu, Hydrocerussitum (Ceruse) and mix and be ground into superfine powder to cross 100 mesh sieves standby.After Oleum Sesami put fried material pot internal heating, it was fried to shrivelled to put into the plant medicine thing again, drags for and removes slag, put into the Radix Arnebiae (Radix Lithospermi) after moistening again, low baking temperature is fried to be removed slag, filters to shrivelled, gets aubergine medicine oil, when medicine oil cooling to 130 ℃, put into vaseline and fully stirring, when being cooled to 90 ℃, put into the minerals medicine that is ground into fine powder, after stirring, promptly can be made into the ointment of the present invention's medicine.After this can inject in the plastic-aluminum pipe and pack.
Claims (2)
1, a kind of medicine for the treatment of burn and scald, it is characterized in that, described medicine is made by effective ingredient and adjuvant, adjuvant is Oleum Sesami, vaseline, behind Oleum Sesami effective component extracting Radix Arnebiae (Radix Lithospermi), Radix Paeoniae Rubra, Radix Sophorae Flavescentis, living Fructus Forsythiae, phellodendron bark, Gardenia, the living Radix Angelicae Dahuricae, Radix Glycyrrhizae, mix with effective ingredient Realgar, Borneolum Syntheticum, dry Alumen, living Alumen, Indigo Naturalis, Colophonium, Sanguis Draxonis, catechu, Hydrocerussitum (Ceruse) and adjuvant vaseline, its weight proportion is again
Radix Arnebiae (Radix Lithospermi) 50～150 weight portions
Radix Paeoniae Rubra 50～150 weight portions
Radix Sophorae Flavescentis 30～90 weight portions
Give birth to Fructus Forsythiae 30～90 weight portions
Phellodendron bark 30～90 weight portions
Gardenia 20～60 weight portions
Give birth to the Radix Angelicae Dahuricae 10～30 weight portions
Radix Glycyrrhizae 10～30 weight portions
Realgar 10～20 weight portions
Borneolum Syntheticum 10～20 weight portions
Dry Alumen 8～20 weight portions
Give birth to Alumen 2～8 weight portions
Indigo Naturalis 10～20 weight portions
Colophonium 5～15 weight portions
Sanguis Draxonis 4～10 weight portions
Catechu 5～10 weight portions
Hydrocerussitum (Ceruse) 2～6 weight portions
Oleum Sesami 2500 weight portions
Vaseline 500 weight portions
2, a kind of medicine for the treatment of burn and scald as claimed in claim 1 is characterized in that wherein the weight proportion of each raw material is
Radix Arnebiae (Radix Lithospermi) 50～100 weight portions
Radix Paeoniae Rubra 50～150 weight portions
Radix Sophorae Flavescentis 30～60 weight portions
Give birth to Fructus Forsythiae 30～60 weight portions
Phellodendron bark 30～60 weight portions
Gardenia 20～40 weight portions
Give birth to the Radix Angelicae Dahuricae 10～20 weight portions
Radix Glycyrrhizae 10～20 weight portions
Realgar 10～15 weight portions
Borneolum Syntheticum 10～15 weight portions
Dry Alumen 8～12 weight portions
Give birth to Alumen 2～4 weight portions
Indigo Naturalis 10～15 weight portions
Colophonium 5～8 weight portions
Sanguis Draxonis 4～6 weight portions
Catechu 5～7 weight portions
Hydrocerussitum (Ceruse) 2～4 weight portions
Oleum Sesami 2500 weight portions
Vaseline 500 weight portions
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310105749 CN1279952C (en) | 2003-11-28 | 2003-11-28 | Medicine for treating burn and scald |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200310105749 CN1279952C (en) | 2003-11-28 | 2003-11-28 | Medicine for treating burn and scald |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1621049A CN1621049A (en) | 2005-06-01 |
| CN1279952C true CN1279952C (en) | 2006-10-18 |
Family
ID=34757390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200310105749 Expired - Fee Related CN1279952C (en) | 2003-11-28 | 2003-11-28 | Medicine for treating burn and scald |
Country Status (1)
| Country | Link |
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| CN (1) | CN1279952C (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100341551C (en) * | 2005-04-05 | 2007-10-10 | 胡仕英 | Chinese medicine for treating burn and scald |
| CN101181401B (en) * | 2007-11-16 | 2010-11-10 | 刘玉英 | Chinese medicine medicament for curing empyrosis |
| CN101342285B (en) * | 2008-08-19 | 2010-12-29 | 李振军 | Chinese medicinal composition for treating exterior trauma and preparation method thereof |
| CN101439114B (en) * | 2008-12-31 | 2011-08-10 | 赵皓 | Chinese medicine for treating burn and scald, and preparation method thereof |
| CN105687797A (en) * | 2016-03-17 | 2016-06-22 | 徐美英 | Medicine preparation for treating burns and scalds and application of medicine preparation |
| CN107213282A (en) * | 2017-07-03 | 2017-09-29 | 潘丽娟 | A kind of traditional Chinese herb medicine for treating scorchingly hot flourishing type burn and preparation method thereof |
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2003
- 2003-11-28 CN CN 200310105749 patent/CN1279952C/en not_active Expired - Fee Related
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| CN1621049A (en) | 2005-06-01 |
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Granted publication date: 20061018 Termination date: 20091228 |