CN1279448C - Monitoring equipment and monitored equipment - Google Patents
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Abstract
Description
技术领域technical field
本发明涉及一种系统,在该系统中,一监控设备通过一通信网络远程控制多个要被监控的设备,以便预测每个被监控设备的故障等。The present invention relates to a system in which a monitoring device remotely controls a plurality of devices to be monitored through a communication network in order to predict failure and the like of each monitored device.
背景技术Background technique
通常,对于包括临床检测设备的各种检测设备、机床或汽车,或者各种类型的其它需要精确操作的设备来说,在设备交付使用之后,这些设备的生产商/经销商将继续进行维护以维持设备的性能,保证安全性。特别是,设备出现故障会妨碍设备操作者进行顺畅的操作,也可能会危及操作者的安全。因此,从提高顾客满意度、抑制维护成本的增加和保证安全的角度考虑,对设备进行定期检查并预先更换消耗性部件等,从而预防故障的发生是非常重要的。Usually, for various testing equipment, including clinical testing equipment, machine tools or automobiles, or various types of other equipment that requires precise operation, after the equipment is delivered to use, the manufacturer/distributor of these equipment will continue to perform maintenance to Maintain equipment performance and ensure safety. In particular, failure of the equipment prevents smooth operations by the operator of the equipment and may also endanger the safety of the operator. Therefore, from the viewpoint of improving customer satisfaction, suppressing increases in maintenance costs, and ensuring safety, it is very important to prevent failures by regularly inspecting equipment and replacing consumable parts in advance.
按照惯例,进行定期检查和更换部件的时间通常由人们根据以往的经验规则适当地设定。或者,也有根据每个部件的使用年限的数据来设定这些时间的情况。By convention, the timing of periodic inspections and parts replacement is usually set appropriately by people based on past rules of thumb. Alternatively, these times may be set based on the data of the service life of each component.
但是,在检查/更换的时间仅根据上述的以往经验或每个部件的使用年限数据等来设定的情况下,由于使用条件等的差异,即使是相同类型的部件之间使用寿命也会有所不同,因此会带来下述的问题。即,与预期的情况相反,有可能会在一次检查/更换时间之前发生故障,或者与此相反,也有可能在部件还有足够的使用年限时就不得不将其更换,这反而引起维护成本的增加,而这恰恰是不利的。However, in the case where the timing of inspection/replacement is set based only on the above-mentioned past experience or the service life data of each part, etc., there may be differences in service life even between parts of the same type due to differences in usage conditions, etc. are different, which leads to the following problems. That is, contrary to expectations, there is a possibility that a failure may occur before the time for an inspection/replacement, or, conversely, that a component may have to be replaced before it has a sufficient lifespan, which in turn causes an increase in maintenance costs. increase, and this is precisely detrimental.
发明内容Contents of the invention
鉴于以上情况,本发明的目的之一就是提供一种监控系统,该系统通过一通信网络监控一被监控设备的状态,可实现在适当的时间对该被监控设备进行维护检查,以检测出异常情况的迹象,从而使该设备实现更高的正常运行率,同时抑制维护成本的增加。In view of the above, one of the objects of the present invention is to provide a monitoring system, which monitors the status of a monitored device through a communication network, and can realize maintenance and inspection of the monitored device at an appropriate time to detect abnormalities indication of the condition, allowing the equipment to achieve a higher uptime rate while inhibiting the increase in maintenance costs.
为了实现上述目的,根据本发明的一种监控设备包括:状态数据接收部分,通过一通信网络从一被监控设备接收表示该被监控设备状态的状态数据;条件存储部分,存储预测条件;以及状态监控部分,将状态数据与条件存储部分中的预测条件进行比较以预测异常情况。在该设备中,预测条件包括基于被监控设备中出现异常情况的时间点之前的状态数据中表示异常前兆的变化模式而产生的预测条件。In order to achieve the above object, a monitoring device according to the present invention includes: a state data receiving part, which receives state data representing the state of the monitored device from a monitored device through a communication network; a condition storage part, which stores prediction conditions; and a state A monitoring section that compares state data with predicted conditions in the condition storage section to predict anomalies. In this device, the predictive condition includes a predictive condition generated based on a change pattern indicating an abnormal precursor in the state data before the time point when the abnormal situation occurs in the monitored device.
在这种配置中,对于从被监控设备接收的状态数据,在连续接收这些数据之后,将其与存储在条件存储部分中的预测条件相比较,以便预测出被监控设备的异常。可以使用基于出现异常的时间点之前的状态数据的转变而产生的条件,作为构成预测条件的一个条件,这样就可以更准确地预测到异常情况的出现。因此,可以实现一种监控设备,其允许被监控设备实现下述目标:与传统情况下维护检查的时间根据部件的使用年限数据等适当设定的情况相比,具有较更高的正常运行率;以及可以抑制由被监控设备的制造商/经销商等进行维护服务所产生的维护成本的增加。In this configuration, as for the status data received from the monitored equipment, after the data are continuously received, it is compared with the predicted condition stored in the condition storage section, so that abnormality of the monitored equipment is predicted. A condition based on a transition of state data before the point in time when the abnormality occurred can be used as one of the conditions constituting the prediction condition, so that the occurrence of the abnormal situation can be more accurately predicted. Therefore, it is possible to realize a monitoring device that allows a monitored device to achieve a higher uptime rate than conventionally in a case where the timing of maintenance inspection is appropriately set based on the service life data of components, etc. ; and an increase in maintenance costs resulting from maintenance services performed by manufacturers/distributors, etc. of monitored equipment can be suppressed.
优选地,在该监控设备中,这样产生的预测条件是根据在出现共同异常情况的至少两个被监控设备中观察到的状态数据的转变当中,具有共同变化模式(pattern)的状态数据的转变而产生的条件。Preferably, in the monitoring device, the predictive condition thus generated is based on transitions of the status data having a common pattern of changes among the transitions of the status data observed in at least two monitored devices in which a common abnormal situation occurs conditions that arise.
例如,在出现偶然异常时,出现该异常之前获得的状态数据的变化模式不一定能提供一个可靠的异常的指示。使用根据这样的变化模式而产生的预测条件可能反而会导致预测异常情况的准确性下降。因此,与在上述配置中的情况相同,预测条件是根据出现共同异常时所获得的共同变化模式而产生的,而且这样可设定用于检测异常迹象的遢用预测条件。这样就可以更准确地检测异常情况。For example, when an occasional exception occurs, the pattern of change in status data obtained before the exception does not necessarily provide a reliable indication of the exception. Using prediction conditions based on such variation patterns may instead lead to a decrease in the accuracy of predicting anomalies. Therefore, as in the case of the above-described configuration, prediction conditions are generated based on common change patterns obtained when common abnormalities occur, and thus it is possible to set useless prediction conditions for detecting signs of abnormality. This allows for more accurate detection of anomalies.
优选地,该监控设备还包括:数据存储部分,累积从被监控设备接收的状态数据;以及异常分析部分,使用累积在数据存储部分中的状态数据,根据出现异常情况的时间点之前的状态数据的转变产生预测条件,并将该预测条件存储到条件存储部分中。Preferably, the monitoring device further includes: a data storage part accumulating state data received from the monitored device; and an abnormality analysis part using the state data accumulated in the data storage part to analyze the The transition of generates a prediction condition and stores the prediction condition into the condition storage section.
根据这种配置,该异常分析部分根据在用户实际操作中从被监控设备接收的状态数据产生预测条件,并将该预测条件存储到条件存储部分中。因此,可以客观地产生预测条件,也可以节省为产生预测条件消耗的人的时间和精力。According to this configuration, the abnormality analysis section generates a prediction condition based on the status data received from the monitored device in actual operation by the user, and stores the prediction condition in the condition storage section. Therefore, the prediction conditions can be generated objectively, and the time and effort of a person expended for generating the prediction conditions can be saved.
优选地,在该监控设备中,预测条件还包括根据被监控设备的部件使用年限数据产生的预测条件。Preferably, in the monitoring device, the prediction condition further includes a prediction condition generated according to service life data of components of the monitored device.
根据该配置,根据实际出现异常时的状态数据的转变而产生的预测条件,与根据部件使用年限的数据而产生的预测条件可以结合使用。这样,可以更准确地预测到可能由部件磨损引起的异常,从而允许在更合适的时间执行被监控设备的维护检查。According to this configuration, prediction conditions based on transition of state data when an abnormality actually occurs, and prediction conditions based on component service life data can be used in combination. In this way, anomalies that may be caused by component wear can be more accurately predicted, allowing maintenance checks of the monitored equipment to be performed at more appropriate times.
优选地,在该监控设备中,状态数据包括在被监控设备中的多种传感器的输出,且预测条件包括分别对应于该多种传感器的输出的预测条件。Preferably, in the monitoring device, the status data includes outputs of various sensors in the monitored device, and the prediction conditions include prediction conditions respectively corresponding to the outputs of the various sensors.
根据该配置,监控操作是根据多种类型的状态数据来执行的,这样可以更正确地判断被监控设备的状态,从而可以更准确地预测异常情况。According to this configuration, the monitoring operation is performed based on various types of status data, so that the status of the monitored equipment can be judged more correctly, so that an abnormal situation can be predicted more accurately.
优选地,该监控设备包括一个通信部分,通过通信网络将状态监控部分预测到异常的通知发送给被监控设备。另外,更优选地,该通信部分发送如何修复该异常的指导。Preferably, the monitoring device includes a communication part, which sends a notification that the status monitoring part predicts an abnormality to the monitored device through a communication network. Also, more preferably, the communication part transmits instructions on how to fix the anomaly.
这些配置允许被监控设备的用户采取适当的行动。These configurations allow the user of the monitored device to take appropriate action.
在被监控设备包括光源,且光源的光量作为状态数据输出的情况下,在该监控设备中,用于预测光源异常的预测条件可以是:与光源的光量对应的状态数据的趋势是趋向数值增加,或者与光源的光量对应的状态数据值的变化率偏离了一个预定范围。In the case where the monitored device includes a light source, and the light quantity of the light source is output as status data, in the monitoring device, the prediction condition for predicting the abnormality of the light source may be that the trend of the status data corresponding to the light quantity of the light source tends to increase in value , or the rate of change of the state data value corresponding to the light quantity of the light source deviates from a predetermined range.
也就是说,在光源中出现诸如灯破裂等异常情况之前,光源的光量可能会暂时增加或者变得不稳定。因此,可以使用上述预测条件,借此可以更准确地检测被监控设备中的光源的异常。That is, the light quantity of the light source may temporarily increase or become unstable until an abnormality such as lamp breakage occurs in the light source. Therefore, the above-mentioned predictive conditions can be used, whereby an abnormality of the light source in the monitored device can be detected more accurately.
另外,在被监控设备包括由一脉冲马达所驱动的一部件,且用于驱动该部件的脉冲马达的脉冲数作为状态数据输出的情况下,在该监控设备中,用于预测该部件异常的预测条件可以是:与脉冲马达的脉冲数对应的状态数据值偏离了脉冲数的一预定范围。In addition, in the case where the monitored device includes a part driven by a pulse motor, and the number of pulses of the pulse motor for driving the part is output as status data, in the monitoring device, the The prediction condition may be that the state data value corresponding to the pulse number of the pulse motor deviates from a predetermined range of the pulse number.
例如,在脉冲马达所驱动的部件等的磨擦阻力由于某种原因而增加的情况下,脉冲马达中可能会出现失步(loss of synchronization),导致该部件需要比正常状态下更多的脉冲来执行一预定操作。这样,可以使用上述预测条件,借此可以更准确地检测被监控设备中的这样一个部件的异常情况。For example, in the case where the frictional resistance of a part driven by a pulse motor increases for some reason, a loss of synchronization may occur in the pulse motor, causing the part to require more pulses than normal to Execute a predetermined operation. In this way, the above-mentioned predictive conditions can be used, whereby an abnormality of such a component in the monitored equipment can be detected more accurately.
优选地,在该监控设备中,被监控设备包括一部件,该部件在不能成功完成一预定操作时重复执行该预定操作,直到成功完成为止所执行的该预定操作的重复次数作为状态数据输出,并且用于预测该部件异常的预测条件包括:与该重复次数对应的状态数据值变为高于一个预定范围内的值。这样就可以更准确地检测被监控设备中的这样一个元件的异常。Preferably, in the monitoring device, the monitored device includes a component that repeatedly executes a predetermined operation when it cannot be successfully completed, and outputs the number of repetitions of the predetermined operation performed until it is successfully completed as status data, And the prediction condition for predicting the abnormality of the component includes: the state data value corresponding to the number of repetitions becomes higher than a value within a predetermined range. This makes it possible to more accurately detect anomalies in such a component in the monitored equipment.
为了实现上述目的,根据本发明的被监控设备是由上述监控设备中的任意一个设备所监控的被监控设备,它包括输出状态数据的传感器部分和通过一通信网络将状态数据发送到监控设备的通信部分。In order to achieve the above object, the monitored device according to the present invention is a monitored device monitored by any one of the above-mentioned monitoring devices, which includes a sensor part that outputs status data and a device that sends the status data to the monitoring device through a communication network communication part.
根据该配置,状态数据经一通信网络发送到一监控设备,因而通过远程监控就可以接收异常情况预测服务。这样就可以提供具有较高的正常运行率的被监控设备,并可降低维护成本。According to this configuration, status data is sent to a monitoring device via a communication network, whereby abnormal situation prediction service can be received through remote monitoring. This provides monitored equipment with a high uptime and reduces maintenance costs.
优选地,在该被监控设备中,通信部分在状态数据从传感器部分输出之后立即发送状态数据。这样做的优点在于监控设备总能跟得上被监控设备的最新状态。Preferably, in the monitored device, the communication section transmits the status data immediately after the status data is output from the sensor section. The advantage of this is that the monitoring equipment can always keep up with the latest status of the monitored equipment.
优选地,在该被监控设备中,还具有用以累积从传感器部分输出的状态数据的存储部分,并且通信部分在预定的时间发送在存储部分累积的状态数据,这样做的优点在于使得数据的传输效率提高。Preferably, in this monitored equipment, there is also a storage part in order to accumulate the status data output from the sensor part, and the communication part sends the status data accumulated in the storage part at a predetermined time, the advantage of doing like this is that the data The transmission efficiency is improved.
为了实现上述目的,根据本发明的一第一方法是一个允许计算机执行一处理过程的方法,该方法包括有步骤:从一被监控设备中接收表示该被监控设备状态的状态数据;将一预测条件与该状态数据相比较,其中该预测条件包括根据被监控设备中出现异常的时间点之前的状态数据中表示异常前兆的变化模式而产生的条件;并且当状态数据符合预测条件时向被监控设备提供预测到异常的通知。In order to achieve the above object, a first method according to the present invention is a method for allowing a computer to execute a process, the method comprising the steps of: receiving status data representing the status of the monitored device from a monitored device; Conditions are compared with the state data, wherein the prediction condition includes a condition generated according to a change pattern indicating an abnormal precursor in the state data before the time point when the abnormality occurs in the monitored equipment; and when the state data meets the prediction condition, the monitored The device provides notifications of predicted anomalies.
该程序被读入到计算机中执行,从而实现了根据本发明的监控设备。The program is read into the computer for execution, thereby realizing the monitoring device according to the present invention.
为了实现上述目的,根据本发明的一第二方法是一个允许计算机执行一处理过程的方法,该方法包括有步骤:在一数据存储部分中累积从一被监控设备接收的状态数据;并使用在数据存储部分中累积的状态数据,根据在出现异常的时间点之前的状态数据中表示异常前兆的变化模式产生用于预测异常的条件。In order to achieve the above object, a second method according to the present invention is a method for allowing a computer to execute a process, the method comprising the steps of: accumulating in a data storage section received status data from a monitored device; and using the The state data accumulated in the data storage section generates a condition for predicting abnormality based on a change pattern indicating a precursor of abnormality in the state data before the point in time when the abnormality occurred.
该程序被读入到计算机中执行,从而实现了根据本发明的监控设备,它根据从一运行的被监控设备中获得的状态数据自动产生预测条件。The program is read into a computer for execution, thereby realizing a monitoring device according to the present invention, which automatically generates predictive conditions based on state data obtained from an operating monitored device.
附图说明Description of drawings
图1是显示根据本发明一个实施例的监控系统的配置的示意性框图。FIG. 1 is a schematic block diagram showing the configuration of a monitoring system according to one embodiment of the present invention.
图2是显示作为产生预测条件依据的,在该监控系统中一种被监控的临床检测设备的状态数据的变化模式的实例的图。FIG. 2 is a diagram showing an example of a change pattern of state data of a monitored clinical testing device in the monitoring system as a basis for generating prediction conditions.
图3是显示作为产生预测条件依据的,该临床检测设备的状态数据的变化模式的另一实例的图。FIG. 3 is a diagram showing another example of a change pattern of the state data of the clinical testing device as a basis for generating a prediction condition.
图4是显示作为临床检测设备实例的设备中具有的试片馈送器的结构的透视图。Fig. 4 is a perspective view showing the structure of a test strip feeder included in a device as an example of a clinical testing device.
图5是显示图4所示转子及其外围部分的放大的透视图。FIG. 5 is an enlarged perspective view showing the rotor shown in FIG. 4 and its peripheral portion.
图6是显示沿图4中的线X-X所取的剖面图。FIG. 6 is a cross-sectional view taken along line X-X in FIG. 4 .
图7是显示出现试片卡住的时间点之前的时间周期内执行的100次测量所获得的一组状态数据的变化模式的图。Fig. 7 is a graph showing a change pattern of a set of state data obtained from 100 measurements performed in a period of time before the point in time at which test strip sticking occurs.
图8是显示图7所示的100次测量之前的时间周期内执行的100次测量所获得的一组状态数据的变化模式的图。FIG. 8 is a graph showing a change pattern of a set of state data obtained from 100 measurements performed in a time period preceding the 100 measurements shown in FIG. 7 .
具体实施方式Detailed ways
(实施例1)(Example 1)
参照附图,下面将通过一个实施例描述本发明。Referring to the accompanying drawings, the present invention will be described below by way of an embodiment.
如图1所示,在根据本实施例的一监控系统的配置中,诸如临床检测设备等设备的设备制造商/经销商的主计算机100(监控设备),通过诸如因特网的一通信网络300,与已经由该制造商/经销商交付用户使用的一临床检测设备200(被监控设备)相互连接。在图1中,为了简便起见,只示出了一台临床检测设备200。但是,也可以有任意数量的临床检测设备200与主计算机100连接。As shown in FIG. 1, in the configuration of a monitoring system according to the present embodiment, the host computer 100 (monitoring equipment) of an equipment manufacturer/distributor such as clinical testing equipment, through a
通信网络300并不限于上述的因特网,它可由能够进行双向通信的任何通信介质形成。通过该通信网络300,表示设备的状态的数据(以下称作状态数据)、误差信号、故障信号等从临床检测设备200传送至主计算机100。另外,数据请求信号、操作临床检测设备200的手册内容等由主计算机100传送至临床检测设备200。The
在本实施例中,“误差”指的是主要由于用户的操作上的错误所造成的操作异常,并且其不需要对设备本身进行修理等。例如,“误差”可以是由于用户未放置测量用的试纸而终止测量的一种现象。这种情况并不需要进行修理等,因为一旦用户放置了试纸就可以返回至正常状态。另一方面,“故障”则是指主要是由于设备中产生的异常造成操作上的异常,并且需要进行修理、更换部件等的一种现象。作为监控设备的主计算机100用来预测故障。In the present embodiment, "error" refers to operational abnormality mainly caused by a user's operational error, and it does not require repair or the like of the device itself. For example, "error" may be a phenomenon in which measurement is terminated because the user does not place the test paper for measurement. This situation does not require repairs, etc., since the normal state can be returned to once the user has placed the test strip. On the other hand, "failure" refers to a phenomenon in which abnormality in operation is mainly due to an abnormality generated in equipment, and repair, replacement of parts, etc. are required. The
如图1所示,主计算机100包括通信部分101、控制部分102、数据存储部分103、条件存储部分104、状态监控部分105和异常分析部分106。As shown in FIG. 1 , the
通信部分101通过通信网络300将上述这些数据等发送至临床检测设备200并从其接收这些数据。控制部分102根据预定程序控制主计算机100的各个部分的操作。数据存储部分103存储从临床检测设备200传送的状态数据。条件存储部分104存储在状态数据中出现并表示异常的条件(称作预测条件)。状态监控部分105通过与预测条件相比较来监控状态数据,以判断是否需要对临床检测设备200进行维护操作等。在出现故障的情况下,异常分析部分106使用在故障出现的时间点之前获得的状态数据,来分析作为故障的迹象的已产生的状态数据的变化。The
如图1所示,临床检测设备200包括通信部分201、控制部分202、部件传感器203a·203b等,以及显示部分204。在图1中,为了简便起见,对于临床检测设备200来说,只示出了与异常预测相关的控制系统的功能块。但是也可设置例如用于实现临床检测设备200预期目的的任意功能块。As shown in FIG. 1 , the
通信部分201通过通信网络300将上述这些数据等发送至主计算机100并从其接收这些数据。控制部分202根据预定程序控制临床检测设备200的各个部分的操作。部件传感器203a·203b等是分别与在临床检测设备200的构成部件中至少那些可能导致操作异常的部件相连接的传感器。部件传感器203a·203b等以状态数据的形式产生输出,其中状态数据表示这些部件中的每个部件的状态。显示部分204在一屏幕上除了向用户显示作为提示的信息和从主计算机100传送的操作手册的内容之外,还显示通知用户误差、故障等的信息。The
下面将说明在使用一尿液分析设备作为临床检测设备200时,该监控系统的操作。The operation of the monitoring system when a urine analysis device is used as the
作为临床检测设备200的尿液分析设备使用喷嘴从固定在样品架中的spitz管中吸取样品(尿液),并将其点滴至试纸的试垫上。随后,该设备将具有预定波长的光发射到该试纸上,以测量光的反射率,从而对尿糖、尿蛋白等进行测定。另外,该设备还具有根据照射到样品架中的样品上的光的折射率测定比重的功能,以及使用散射光测定混浊度的功能。该设备还包括一个传送部分,用以在水平方向上移动样品架,这样就可以在该设备与另一设备之间建立自动传送线,它们之间可以共享一个共用样品架,也可以按顺序使用多个样品架。The urine analysis device as the
因而,作为部件传感器203,该尿液分析设备在相应的部分中包括各种类型的传感器,例如:(1)对使用注射泵的次数进行计数以允许吸管执行吸取操作并输出因此获得的次数的传感器,(2)确定空气泵(隔膜泵)的运行时间并输出因此获得的时间的传感器,(3)测量排液通道中的压力并输出因此获得的压力值的传感器,(4)测量用于测量的光源灯的光量并输出因此获得的光量的传感器,以及(5)测量样品架传送部分的磨擦阻力并输出因此获得的磨擦阻力的传感器。Thus, as the component sensor 203, this urine analysis apparatus includes various types of sensors in corresponding parts, for example: (1) a device that counts the number of times the syringe pump is used to allow the suction pipe to perform a suction operation and outputs the number of times thus obtained Sensor, (2) sensor for determining the operating time of the air pump (diaphragm pump) and outputting the resulting time, (3) sensor for measuring the pressure in the discharge channel and outputting the resulting pressure value, (4) measuring for A sensor that measures the amount of light of the light source lamp and outputs the amount of light thus obtained, and (5) a sensor that measures the frictional resistance of the sample holder conveying portion and outputs the resulting frictional resistance.
从各个传感器分别输出的这些数据的时间应当根据各部件的相应性能而任意设定。另外,一个部件可以具有两个或更多类型的部件传感器203,这样就可以检测两种或更多类型的状态数据。例如,在上述的注射泵中,除了对使用次数进行计数的传感器之外,另外还可具有一种作为部件传感器203的传感器,其用于检测对于驱动注射器垂直移动的脉冲马达,当注射器向上和向下移动时分别获得的驱动脉冲数。The timing of these data respectively output from each sensor should be set arbitrarily according to the corresponding performance of each component. In addition, one component may have two or more types of component sensors 203 so that two or more types of status data can be detected. For example, in the above-mentioned syringe pump, in addition to the sensor that counts the number of times of use, there may also be a sensor as the component sensor 203, which is used to detect the pulse motor that drives the syringe vertically. Number of drive pulses to get respectively when moving down.
在控制部分202的控制下,分别从上述部件传感器203输出的数据(状态数据)根据请求从通信部分201经由通信网络300传送到主计算机100。随后,这些数据被存储到数据存储部分103中。Under the control of the
每次当状态数据从每个部件传感器203输出时,状态数据可从临床检测设备200发送到主计算机100。或者,临床检测设备200中可以具有一个临时存储状态数据的存储器(未示出),这样,在状态数据累积到一定的量之后,可以发送累积的状态数据组。前一种方法的优点在于可实现主计算机100中总是能保持跟踪临床检测设备200的最新状态。后一种方法的优点在于数据传输效率得到提高。The status data may be sent from the
在主计算机100中,状态监控部分105将存储在数据存储部分103中的状态数据与存储在条件存储部分104中的预测条件相比较,以判断临床检测设备200的状态。In the
作为预测条件的初始值,基于每个部件的使用年限数据等的条件在条件存储部分104中设定。例如,对于来自注射泵的如上所述(1)中获得的状态数据来说,设置“使用次数达到10,000”作为预测条件的初始值。另外,对于来自空气泵的如上所述(2)中获得的状态数据来说,设置“使用时间达到5,000小时”作为预测条件的初始值。对于来自排液通道的如上所述(3)中获得的状态数据来说,设置“在泵驱动开始5秒后通道中的压力的降低小于60kPa”作为初始值。对于来自测量用的光源灯的如上所述(4)中获得的状态数据来说,设置“灯的光量降至不高于初始值的70%”作为初始值。对于来自样品架传送部分的如上所述(5)中获得的状态数据来说,设置“磨擦达到不小于某个值(N)”作为初始值。As initial values of prediction conditions, conditions based on the service life data of each component and the like are set in the
另外,在条件存储部分104中,还与这些条件中的每个条件相关联地存储了一种情况处理方法以备用。例如,对于满足与上述(1)有关的注射泵的预测条件的情况,将“润滑注射泵”和“更换O形圈”存储为情况处理方法。另外,对于满足与(2)有关的空气泵的预测条件的情况,将“更换该泵”存储为一种情况处理方法。对于满足与(3)有关的排出通道的预测条件的情况,将“清理通道内的堵塞,或者确认该泵的性能下降以在必要时更换该泵”存储为一种情况处理方法。对于满足与(4)有关的光源灯的预测条件的情况,将“更换该灯”存储为一种情况处理方法。对于满足与(5)有关的样品架传送部分的预测条件的情况,将“清洁引起磨擦的部分”存储为一种情况处理方法。In addition, in the
状态监控部分105把来自临床检测设备200的状态数据与预测条件相比较。如果状态数据满足预测条件,则状态监控部分105通过通信部分101和通信网络300向临床检测设备200发送例如,给出有关与条件存储部分104中的预测条件相关存储的情况处理方法的指示的信息,以及指示非常有可能出现异常情况的警告的信息。在临床检测设备200中,通信部分201接收到这些信息之后,显示部分204在控制部分202的控制下在屏幕上显示该情况处理方法。这样,该临床检测设备200的用户可以根据显示在屏幕上的信息等执行该情况的自处理。或者,在自处理无效的情况下,可以请求派遣维护人员。The
然而,在实际当中,受到例如使用状态、维护状态,或者生产部件时的条件差异等的影响,在某些情况下,异常情况可能在状态数据满足最初设定的预测条件之前产生。相反地,在其它一些情况下,甚至在状态数据满足预测条件的时间点之后也没有出现异常。However, in practice, due to influences such as usage status, maintenance status, or condition differences when producing components, in some cases, abnormal situations may occur before the status data meets the initially set prediction conditions. Conversely, in some other cases, no abnormality occurs even after the point in time at which the state data satisfies the prediction condition.
鉴于这种情况,正如下文中所要描述的,当实际出现异常时,根据本实施例的主计算机100查阅存储在数据存储部分103中的状态数据。然后主计算机100根据就在异常情况出现之前获得的状态数据的变化模式产生一个新的预测条件并将其添加到条件存储部分104中。此后,状态监控部分105将初始设置的预测条件以及该添加的预测条件与状态数据相比较,以便监控临床检测设备200。如果状态数据满足其中的任意预测条件,则状态监控部分105将上述信息等(即,例如发出警告的信息以及给出关于对临床检测设备200的情况处理的指示信息)传送给临床检测设备200。In view of this, as will be described hereinafter, the
下面将说明一种在出现异常时设置新的预测条件的方法。该方法根据在异常出现之前获得的状态数据的变化模式进行设定。这里具体描述了在上述尿液分析设备中测量用的光源灯发生破裂的实例。A method for setting new prediction conditions when an exception occurs will be explained below. The method is set according to the change pattern of the status data obtained before the abnormality occurs. An example in which the light source lamp for measurement is broken in the above urine analysis apparatus is specifically described here.
图2是显示来自测量用光源灯的状态数据的转变的图,即由任意一个部件传感器203测量并发送给主计算机100的该灯的光量。如图所示,在开始使用该灯大约6000小时之后,该灯破裂。FIG. 2 is a graph showing the transition of status data from the light source lamp for measurement, that is, the light quantity of the lamp measured by any one of the component sensors 203 and sent to the
当光源灯发生破裂时,用于该灯的部件传感器203检测到发生故障,即“光源灯发生破裂”,并输出一预先分配给这种故障类型的故障信号。该故障信号通过通信部分201和通信网络300发送给主计算机100。When the light source lamp breaks, the component sensor 203 for the lamp detects the failure, ie, "the light source lamp breaks", and outputs a failure signal assigned in advance to this type of failure. The failure signal is sent to the
在主计算机100中,通信部分101接收到该故障信号之后,在控制部分102的控制下,异常分析部分106从数据存储部分103中提取在接收到该故障信号的时间点之前的一预定周期内获得的状态数据。随后,异常分析部分106分析该提取的状态数据,提取一变化模式作为异常表示,并设置一个新的预测条件。In the
例如,在图2所示的状态数据中,作为状态数据的灯的光量在灯开始使用之后逐渐下降。但是,如从该图中可以看出的,在灯破裂之前,光量呈现出一种转为增加的趋势。因此,作为一个新的预测条件,将“灯的光量增加”添加在条件存储部分104中。这样,此后,对于作为光源灯的状态数据的灯的光量,当满足“灯的光量降至不高于初始值的70%”的条件和“灯的光量增加”的条件中的任意一个时,将发出报警等的信息。For example, in the status data shown in FIG. 2 , the light quantity of the lamp as the status data gradually decreases after the lamp starts to be used. However, as can be seen from the figure, the light quantity shows a tendency to turn to increase before the lamp breaks. Therefore, "increased light quantity of lamp" is added in the
另外,在例如灯的光量具有如图3所示的变化模式的情况下,如从图中可以看出的,灯发生破裂之前的光量是不稳定的。因而,在这种情况下,可在条件存储部分104中新添加例如“灯的光量变化率偏离一预定范围”作为一个预测条件。In addition, in the case where, for example, the light quantity of the lamp has a change pattern as shown in FIG. 3 , as can be seen from the figure, the light quantity before the lamp breakage is unstable. Thus, in this case, for example, "the rate of change of the light quantity of the lamp deviates from a predetermined range" may be newly added in the
此外,对于上述注射泵来说,例如在满足初始设置的预测条件之前(即使用次数达到10,000之前)在注射器的垂直驱动中出现故障的情况下,对于驱动注射器垂直移动的脉冲马达,可对注射器向上和向下移动时分别获得的驱动脉冲的数量进行分析。结果,可以看出,在出现异常的时间点之前产生了4个或更多个脉冲的偏差。在这种情况下,应当将“当脉冲马达的注射器向上和向下移动时分别获得的驱动脉冲数之间的差值达到4以上”作为一个新的预测条件存储到条件存储部分104中。In addition, for the above-mentioned syringe pump, for example, in the case where a failure occurs in the vertical drive of the syringe before the predicted condition set initially (i.e., before the number of uses reaches 10,000), for the pulse motor that drives the syringe to move vertically, it is possible to control the syringe. The number of drive pulses obtained separately when moving up and down is analyzed. As a result, it can be seen that a deviation of 4 or more pulses is generated before the point in time when the abnormality occurs. In this case, "the difference between the number of drive pulses obtained when the syringe of the pulse motor moves up and down
如上所述,根据本实施例的配置,基于部件使用年限等的预测条件在条件存储部分104中进行初始设置。在实际出现故障时,将根据出现故障的时间点之前获得的状态数据的变化模式产生的一个新的预测条件添加到条件存储部分104中。这将允许状态监控部分105更准确地检测出异常的迹象。As described above, according to the configuration of the present embodiment, prediction conditions based on component service life and the like are initially set in the
基于状态数据变化模式的新预测条件可由异常分析部分106根据一预定算法而产生,或者也可由人们根据异常分析部分106所提取和分析的变化模式创建并设置。The new prediction condition based on the state data change pattern can be generated by the
(实施例2)(Example 2)
下面将通过另一个实施例来描述本发明。Next, the present invention will be described by another embodiment.
在本实施例中,作为临床检测设备200的一个例子,所使用的设备配备有试片馈送部分(图1中未示出),用以向一检测部分提供试片。下面的描述将着重于一机构,其中该设备的操作异常由主机100来预测。In this embodiment, as an example of the
如图4所示,包含于临床检测设备200中的一试片馈送器是一种向一预定检测部分连续提供试片的机构,一次提供一个。试片是一种薄而短的片,其一侧的表面上放置了许多不同类型的试剂垫。As shown in FIG. 4, a test strip feeder included in the
如图4所示,该试片馈送器包括底座1、支架2、支承构件3a和3b、转子4、存放部分5、试片检测块6、斜盖7、鼓8、底座构件9、驱动部分10和鼓控制部分(未示出)。该鼓控制部分由微型计算机等构成。As shown in Figure 4, the test piece feeder includes a base 1, a
支承构件3a和3b、存放部分5和试片检测块6形成了供给部分11的外围侧壁,在供给部分11中提供了多个试片。转子4从供给部分11中一次取出一个试片,将其提供给鼓8。光电传感器6a(见图6)结合在了试片检测块6的内部。该传感器检测从转子4馈送至鼓8的一个试片的各面。The supporting
用于向转子4和鼓8提供旋转动力的脉冲马达10A置于驱动部分10中。脉冲马达10A的驱动轴通过一驱动传送系统10B与转子4和鼓8的旋转轴耦合,该驱动传送系统10B包括一传送带、皮带轮10Ba和10Bb等,其中的一部分并未在图中示出。A
在该试片馈送器中,作为图1中所示的部件传感器203,具有包括光电传感器6a的各种类型的传感器,用以向主计算机100提供每个部件的状态数据。In this test strip feeder, as the part sensor 203 shown in FIG.
图5是显示图4所示转子4及其外围部分的放大的透视图。图6是沿图4的线X-X所取的剖面图。如图4至6所示,转子4外部形状为总体上长度大于宽度的柱状,并概略地由外围部分4a、旋转轴4b和轮辐构件4c构成。外围部分4a形成长度大于宽度的圆柱形,且其纵向的长度大体相当于试片的纵向长度。旋转轴4b位于外围部分4a内部的中心,它通过轮辐构件4c与外围部分4a的内侧面4aa连接。该旋转轴4b的每个末端部分被插入到位于每个支承构件3a和3b的一预定部分的一通孔中。设置转子4,使其在由支承构件3a和3b间的轴支撑的同时可以旋转。FIG. 5 is an enlarged perspective view showing the
同时,在外围部分4a的外侧面4ab上形成了多条沟槽线形状的凹入部分4d,其沿着旋转方向形成一圈。另外,在外侧面4ab上形成了长度大于宽度的沟槽部分4e,使得一个试片可以沿着垂直于旋转方向的长度方向配合地放置在沟槽部分4e中。Simultaneously, a plurality of
在驱动部分10的控制下,转子4在沟槽部分4e位于存放部分5之下的位置(初始位置)和光电传感器6a能够判断沟槽部分4e中是否有试片的位置(判断位置)之间执行往复旋转运动。旋转角度根据脉冲马达10A的驱动脉冲数来控制,且转子4的旋转位置由光电传感器6a检测。也就是说,当脉冲马达10A由预定数量的脉冲(如500个脉冲)驱动,从初始位置开始旋转转子4时,如果光电传感器6A检测到转子4处于判断位置,则其判断转子4正常运行。Under the control of the driving
当用户将多个试片纵向对齐地提供在供给部分11中时,如图3所示,转子4从初始位置开始逆时针旋转。此时,位于供给部分11的底部的一个试片,在配合地置于转子4的沟槽部分4e中的同时,随着转子4的旋转向试片检测块6的方向移动。在这种情况下,提供在供给部分11中的多个试片堆集到包含沟槽部分4e的转子4的外侧面4ab上。当沟槽部分4e移动到其面对试片检测块6的位置上时,堆集在沟槽部分4e中的试片由分离板6e拣选为仅仅一个试片。When the user supplies a plurality of test pieces in the
转子4进一步旋转,这样,放置在沟槽部分4e中的一个试片,在与沟槽部分4e结合在一起的同时,经过试片检测块6并到达判断位置。在此位置,试片检测块6的光电传感器6a检测是否有试片放置在沟槽部分4e中。当光电传感器6a检测到试片的情况下,也就是说,当其确认转子4已旋转到判断位置的情况下,驱动部分10进一步以预定数目的脉冲驱动马达10A,使转子4在逆时针方向上继续旋转。这样,该试片被送出至倾斜通道12。The
如果在转子4已旋转了500个脉冲之后,光传感器6a仍未检测到转子4已旋转到判断位置,可以想到,原因在于试片被卡在转子4和分离板6e之间,因而妨碍了转子4的旋转。If the
在这种情况下,为了取出被卡住的试片,如上所述,驱动部分10将转子4移回到初始位置并重新开始旋转操作。驱动部分10中的部件传感器203向主计算机100输出执行此操作直到一个试片被送到斜通道12中的次数(尝试次数)作为状态数据。在此操作重复了预定的次数(如50次)之后仍未检测到转子4已旋转到判断位置的情况下,表示发生“试纸卡住”的一故障信号从驱动部分10的部件传感器203输出,并通过通信部分201和通信网络300传送给主计算机100。In this case, in order to take out the jammed test piece, as described above, the
在主计算机100中,通信部分101接收到该故障信号之后,在控制部分102的控制下,异常分析部分106从数据存储部分103中提取在接收到该故障信息的时间点之前的一适当周期内获得的状态数据。In the
在此,假设异常分析部分106提取例如发生“试纸卡住”的时间点之前的一时间周期中,所执行的100次测量所获得的状态数据(即,取出100个试片所执行的尝试次数),作为出现异常的时间点之前获得的状态数据。图7示出了该状态数据的变化模式。另外,异常分析部分106从数据存储部分103中,提取在该100次测量之前的一时间周期内所执行另外100次测量获得的状态数据,作为在正常状态下的数据,以便与出现异常之前所获得的状态数据进行比较。图8示出了在正常状态下的该数据的变化模式。Here, it is assumed that the
通过比较图7和图8可以看出,在正常状态下(图8),直到将一个试片取出所执行的尝试的次数平均为3到4次,而就在出现异常的时间点之前(图7),尝试的次数突然增加到平均6到10次。因此可将例如“尝试的平均次数达到9次或更多”作为一个新的预测条件添加到条件存储部分104中。这样,此后状态监控部分105可根据该预测条件监控作为状态数据的尝试次数,从而可以检测到出现试纸卡住的迹象。By comparing Fig. 7 and Fig. 8, it can be seen that in the normal state (Fig. 8), the number of attempts performed until a test piece is taken out is an average of 3 to 4 times, and just before the time point when abnormality occurs (Fig. 7), the number of attempts suddenly increased to an average of 6 to 10 times. Therefore, for example, "the average number of attempts reaches 9 times or more" can be added to the
另外,在驱动部分10中,还提供另一种类型的部件传感器203,它向主计算机100输出转子4从初始位置向判断位置旋转所需的脉冲马达10A的馈送脉冲数作为状态数据。由该部件传感器203获得的状态数据由异常分析部分106分析。结果是,可以发现在正常情况下,从初始位置向判断位置旋转所需的馈送脉冲数是如上所述的500个脉冲,而就在出现试纸卡住的时间点之前,该数目不少于560个脉冲。In addition, in the
因此,还可以向条件存储部分104中添加“脉冲马达的馈送脉冲数达到不少于550个脉冲”作为一个新的预测条件,从而实现更精确地检测发生试纸卡住的迹象。Therefore, it is also possible to add "the number of feeding pulses of the pulse motor to not less than 550 pulses" as a new predictive condition to the
就在出现试纸卡住的时间点之前,由于下述原因,所执行的尝试次数增加,或者脉冲马达的馈送脉冲数增加。即,由试片产生的尘土会沾在转子4的表面以及沟槽4e等中,这样试片就更有可能卡在转子4和分离板6e之间,且转子4的旋转磨擦阻力会增加。因而,优选地,在检测到出现试纸卡住的迹象时,从主计算机100向临床检测设备200传送一个给出“清洁转子和沟槽部分”的指示的信息作为一种情况处理方法。这种配置使临床检测设备200的用户在出现试片卡住的迹象时可以采用适当的动作,从而防止故障,即试片卡住在实际中发生。Just before the point in time at which the test paper jam occurs, the number of attempts performed increases, or the number of feeding pulses of the pulse motor increases, for the reasons described below. That is, the dust generated by the test piece will stick to the surface of the
在上面的描述中,每次出现异常情况时,将根据状态数据的变化模式添加一个新的预测条件。但是,例如在一个特定使用条件下等偶然出现一个异常情况时,在出现该异常情况之前所获得的状态数据的变化模式可能并不一定提供一个可靠的异常迹象。使用根据这样一个变化模式产生的预测条件可能反而会导致预测异常情况的准确性下降。In the above description, every time an abnormal situation occurs, a new prediction condition will be added according to the change pattern of the state data. However, when an abnormal condition occurs occasionally, such as under a specific usage condition, the change pattern of the state data obtained before the abnormal condition occurs may not necessarily provide a reliable indication of the abnormal condition. Using predictive conditions based on such a changing pattern may instead lead to a decrease in the accuracy of predicting anomalies.
因此,在主计算机100中,当多个临床检测设备200的每个设备中出现一个共同的故障时,对每个临床检测设备200的状态数据进行分析,并且,例如只有在预定数量或高于该预定数量的临床检测设备200中观察到一共同的变化模式时,才会根据该变化模式产生一个新的预测条件。这样,可以设定用于检测一种异常的迹象的一个通用预测条件,借此能更准确地预测异常情况。Therefore, in the
在这种情况下,对于多个临床检测设备200中的每一个来说,包括生产批号、生产日期,以及用在每个部分中的部件的生产批号的数据(与生产相关的数据)也可被存储到数据存储部分103中,或者存储到在主计算机100中用于存储这些与生产相关的数据的一存储部分中。随后,当从多个临床检测设备200中检测到共同的异常数据时,主计算机100根据存储在数据存储部分103等中的与生产相关的数据,确定出现异常的每个临床检测设备200的生产批号、在出现异常的部分中使用的部件的生产批号等。另外,在例如设备的生产批号及出现异常的部件的生产批号等,对于全部或者一部分出现异常的多个临床检测设备200相同的情况下,则从被监控的临床检测设备200中确定那些具有该相同生产批号的临床检测设备200,或者使用了具有该相同生产批号的出现异常的部件的临床检测设备200。这样,对这些被确定出来的临床检测设备200,可采取适当的行动来防止故障的发生。In this case, for each of the plurality of
本发明并不限于上述实施例,在本发明的范围之内可以对其进行各种改进。例如,在上面的描述中,在用户实际使用临床检测设备200的操作期间,状态数据根据需要被发送给主计算机100,在出现异常之后,产生一个新的预测条件。但是,除了这样的配置以外,预测条件可根据当一测试运行的临床检测设备200中出现异常时由临床检测设备200的制造商/经销商所获得的状态数据的变化模式而产生,并存储在主计算机100的条件存储部分104中以便使用。The present invention is not limited to the above-described embodiments, and various modifications can be made thereto within the scope of the present invention. For example, in the above description, during the actual operation of the
另外,根据本发明的监控设备并不限于如上所述的主计算机,它也可使用任意的计算机,如个人计算机、工作站等来实现。另外,被监控设备并不限于临床检测设备,需要进行检测和维护的任意设备,如汽车等也适用于本发明。另外,不需要进行检查和维护的家用电器也适用于本发明。而且,被监控设备与通信网络之间的连接并不限于有线连接,还可以使用移动通信、无线电连接,如家庭射频(HomeRF)、蓝牙(Bluetooth)等。In addition, the monitoring device according to the present invention is not limited to the host computer as described above, and it can also be realized using any computer such as a personal computer, a workstation, and the like. In addition, the monitored equipment is not limited to clinical testing equipment, and any equipment that requires testing and maintenance, such as automobiles, is also applicable to the present invention. In addition, household appliances that do not require inspection and maintenance are also applicable to the present invention. Moreover, the connection between the monitored device and the communication network is not limited to a wired connection, and mobile communication, radio connection, such as Home RF (HomeRF), Bluetooth (Bluetooth) and the like may also be used.
在上述实施例中描述的每个监控系统中,从用户实际使用的设备中收集状态数据,并根据状态数据的变化模式产生预测条件。另一方面,例如,一种配置也是可行的,在该配置中,由临床检测设备的制造商等使用从生产线上的设备中适当选取的一用于试验的检测设备进行耐久试验,并且根据在该试验期间获得的状态数据而产生预测条件。不过,根据本实施例的监控系统,能够产生符合实际使用环境和使用条件的预测条件,这样与使用基于测试而获得的预测条件的情况相比可以更精确地预测异常情况。In each of the monitoring systems described in the above embodiments, state data is collected from devices actually used by users, and predictive conditions are generated according to change patterns of the state data. On the other hand, for example, a configuration is also possible in which an endurance test is carried out by a manufacturer of clinical testing equipment, etc. Prediction conditions are generated from state data obtained during the test. However, according to the monitoring system of the present embodiment, prediction conditions conforming to actual usage environments and usage conditions can be generated, so that abnormalities can be predicted more accurately than the case of using prediction conditions obtained based on tests.
而且,该监控系统允许多个临床检测设备等通过一个通信网络与一个监控设备连接。如上所述,一种配置也是可行的,在该配置中,由制造商通过使用从生产线上的设备中选取的用于试验的检测设备产生预测条件。但是,通常来说,在一次试验中可使用的设备数量是有限的。另一方面,在根据本实施例的监控系统中,从逻辑角度来说,所有用户的设备都可被监控,并且预测条件可根据从多个设备获得的状态数据而产生。因此可产生更普遍的预测条件,进而可以更准确地预测异常情况。Moreover, the monitoring system allows a plurality of clinical testing devices and the like to be connected with one monitoring device through a communication network. As described above, a configuration is also possible in which the predicted condition is generated by the manufacturer by using the testing equipment selected for the test from the equipment on the production line. However, in general, there is a limit to the number of devices that can be used in a trial. On the other hand, in the monitoring system according to the present embodiment, all users' devices can be monitored logically, and predictive conditions can be generated based on status data obtained from a plurality of devices. As a result, more general predictive conditions can be generated, which in turn can predict anomalies more accurately.
而且,在该监控系统的监控设备中,已产生的合适的新预测条件可随时被添加到条件存储部分中,这样,系统的运行时间越长,累积的预测条件就会越有效,进而可以更加准确地检测到异常情况。这样也就可以实现下面的效果。即,可进一步提高临床检测设备等的正常运行率,从而提高用户的满足度,还可进一步抑制维护成本的增加。Moreover, in the monitoring equipment of the monitoring system, the suitable new prediction conditions that have been generated can be added to the condition storage part at any time, so that the longer the running time of the system, the more effective the accumulated prediction conditions can be. Anomalies are accurately detected. In this way, the following effects can also be achieved. That is, the normal operation rate of clinical testing equipment and the like can be further improved, thereby improving user satisfaction, and further suppressing an increase in maintenance cost.
工业适用性Industrial applicability
如前面的讨论中所述,根据本发明,对被监控设备的状态进行远程监控,因此可以检测出异常情况的迹象,这样可以提供一种在适当时间执行维护检查的监控系统,从而允许被监控设备实现更高的正常运行率,同时抑制维护成本的增加。As described in the foregoing discussion, according to the present invention, the status of the monitored equipment is remotely monitored, so signs of abnormal conditions can be detected, which can provide a monitoring system that performs maintenance checks at appropriate times, thereby allowing the monitored Equipment achieves a higher uptime rate while suppressing increases in maintenance costs.
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-
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- 2002-02-25 WO PCT/JP2002/001641 patent/WO2002066933A1/en not_active Ceased
- 2002-02-25 JP JP2002566610A patent/JP4287653B2/en not_active Expired - Lifetime
- 2002-02-25 EP EP02700732.7A patent/EP1382942B1/en not_active Expired - Lifetime
- 2002-02-25 US US10/468,657 patent/US7047142B2/en not_active Expired - Lifetime
- 2002-02-25 CN CNB028054040A patent/CN1279448C/en not_active Expired - Fee Related
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2009
- 2009-02-04 JP JP2009023830A patent/JP4763811B2/en not_active Expired - Fee Related
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2011
- 2011-03-11 JP JP2011054227A patent/JP5010041B2/en not_active Expired - Fee Related
- 2011-03-11 JP JP2011054228A patent/JP2011146066A/en active Pending
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| JP2011159308A (en) | 2011-08-18 |
| CN1502035A (en) | 2004-06-02 |
| JP2009192533A (en) | 2009-08-27 |
| US20050033527A1 (en) | 2005-02-10 |
| EP1382942B1 (en) | 2016-07-27 |
| JP4287653B2 (en) | 2009-07-01 |
| JP2011146066A (en) | 2011-07-28 |
| JPWO2002066933A1 (en) | 2004-09-24 |
| EP1382942A4 (en) | 2007-05-09 |
| US7047142B2 (en) | 2006-05-16 |
| EP1382942A1 (en) | 2004-01-21 |
| WO2002066933A1 (en) | 2002-08-29 |
| JP5010041B2 (en) | 2012-08-29 |
| JP4763811B2 (en) | 2011-08-31 |
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