CN1268164A - Detergent compositions comprising a specific cellulase and alkyl poly glucoside surfactant - Google Patents

Abstract

The present invention relates to laundry detergent compositions, which contains a fungal cellulase without the cellulose binding stucture domain and having a best pH between 4-10, and an alkyl poly glucoside surfactant, thus providing outstanding washing and whiteness performance results.

Description

Detergent composition containing specific cellulase and alkyl polyglucoside surfactant

Technical field

The present invention relates to laundry detergent compositions comprising specific cellulases and alkyl polyglucoside surfactants.

Background of the Invention

Detergent compositions now include a complex combination of active ingredients for some specific needs: surfactant systems, enzymes to provide cleaning and fabric care benefits, bleaches, builder systems, suds suppressors, soil suspending agents, Detergents, optical brighteners, softeners, dispersants, dye transfer inhibiting compounds, abrasives, bactericides, fragrances, the overall performance of them has indeed improved in recent years. Current detergent formulations often include detergent enzymes and more specifically cellulases among others.

Cellulase activity refers to where cellulose fibers or substrates are hydrolyzed by a cellulase, and depending on the specific function of the cellulase, it can be an endo- or exo-cellulase and the respective hemicellulase. The cellulose structure is depolymerized or broken into smaller, and thus more water soluble or dispersible fractions. The activity on fabrics in particular provides cleaning, restoration, softness and generally improved hand properties to the fabric structure.

Cellulolytic enzymes, i.e. cellulases, have been recognized for some time for their effectiveness as fabric cleaning and roughness reducing agents for fabrics; WO89/09259, GB-A-2075028, GB-A-2095275 and GB-A -2094826 discloses a detergent composition containing cellulase to improve washing performance; GB-A-1368599 discloses the use of cellulase for reducing the roughness of cotton-containing fabrics; Use of a fraction obtained cellulolytic enzyme as a harshness reducing detergent additive.

EP-A-0269168 discloses optimized detergent compositions containing cellulase enzymes formulated in the mildly alkaline pH range and providing combined fabric washing, fabric softening and fabric care performance.

Specific cellulases suitable for use in the present invention are described in WO 91/17244, which describes selected high specific activity monocomponent enzymes and which discloses enzymes capable of degrading cellulose or hemicellulose.

Also suitable are the cellulolytic enzymes disclosed in WO 95/02675, which describes detergent compositions comprising two cellulase components: a first cellulase component having a delayed type of activity and capable of particle removal Soil, a second cellulase component comprising multiple domains comprising at least one non-catalytic domain linked to a catalytic domain and capable of color clarification, wherein at least one cellulase component is a single component. The enzymatic detergent composition is capable of simultaneously providing sufficient color clarification and removal of particulate soils which neither damages nor partially degrades cellulose-containing fabrics after a limited number of wash cycles.

A suitable cellulase is the EGIII cellulase from Trichoderma longibrachiatum described in WO 94/21801, Genencor, published September 29, 1994.

Cellulase inactivation is also known to occur in detergent formulations, one of which is the loss of cellulase activity depending on the presence of co-detergent components, one type of co-detergent components being surfactants.

Various detersive surfactants are known in the literature and in commercial practice which serve a dual function in the detergent matrix. First, the surfactant molecules lower the interfacial tension between the soil and the water phase, thereby gradually removing the stain from the surface by rolling up, emulsification, or solubilization mechanisms. Anionic surfactants are especially suitable for this function. Second, the surfactant molecules keep the dirt in suspension, avoiding redeposition on the surface. Glucoside nonionic and anionic surfactants are commonly used for this purpose.

In fact, existing laundry detergent compositions often contain nonionic surfactants, especially nonionic surfactants with a hydrophilic head. Certain commercially available nonionic surfactants, such as alkyl polyglucoside surfactants, are structurally similar to the cotton-structured glucoside type and are considered due to their ability to maintain high viscosity even at low concentrations. Enhanced washing performance (Tenside Surf. Det28 (1991) 6).

Alkyl polyglucoside surfactants are disclosed in US3598865, 3721633 and 3772269. These patents also disclose processes for the preparation of alkyl polyglucoside surfactants and formulated liquid detergent compositions containing these surfactants. US3219656 discloses alkyl monoglucosides and suggests their use as foam stabilizers for other surfactants. Various polyglucoside surfactant structures and their methods of preparation are disclosed in US Pat.

Alkyl polyglucoside surfactants have been disclosed in combination with several cosurfactants in detergent compositions. US4396520 discloses detergent compositions comprising an alkylpolysaccharide surfactant and a calcium sensitive anionic detergent co-surfactant. US4565647 discloses foaming compositions containing alkyl polysaccharide surfactants and sulphate, sulphonate and/or carboxylate co-surfactants. US4599188 discloses foaming compositions containing alkyl polysaccharide surfactants, sulphate, sulphonate and/or carboxylate co-surfactants and amide and/or amine oxide co-foam boosters. US4732704 discloses hand dishwashing detergent compositions containing alkyl monoglucoside surfactants, anionic surfactants of the sulfate or sulfonate type and fatty acid alkanolamides. US4839098 discloses hand dishwashing detergent compositions containing alkyl polyglucoside surfactants and dialkyl sulfosuccinates.

Alkyl polyglucoside surfactants are also described in WO92/19711, WO92/08439, DE4029035, JP3163198, JO3174796, EP216301, EP280143, WO91/13096 and WO92/19711.

In view of the above, the major technical challenge that remains in formulating detergent compositions is to meet consumer demands for outstanding wash and whiteness performance benefits.

We have now surprisingly found that alkyl polyglucoside surfactants of the type disclosed below provide a specific cellulase-enhancing function. This discovery enables improved performance or reduced surfactant/special cellulase levels while maintaining the same wash performance.

Invention Summary

The present invention relates to laundry detergent compositions comprising specific cellulases and alkyl polyglucoside surfactants which provide outstanding cleaning and whiteness performance benefits.

Detailed Description of the Invention Special Cellulase

The main component of the present invention is special cellulase, and it is generally contained in the present invention with the content of 0.0001%-2%, more preferably 0.0005%-0.05%, most preferably 0.001%-0.01% pure enzyme by total composition weight in laundry detergent compositions.

Particular cellulases suitable for use in the present invention are obtained from fungal strains, preferably selected from the following organisms: Humicola isolens or Trichoderma longibrachiatum, reseei or viride. Another feature of the particular cellulase is that it has a pH optimum of 4-10 and lacks a cellulose binding domain (CBD). The term CBD refers to an amino acid sequence capable of effectively binding a cellulase to a cellulose substrate.

We have now surprisingly found that alkyl polyglucoside surfactants of the type disclosed below provide a specific cellulase-enhancing function. This discovery enables improved performance or reduced surfactant/special cellulase levels while maintaining the same wash performance.

Examples of cellulase components suitable for use in the present invention are:

Endoglucanase fraction that immunoreacts with antibodies raised from highly purified ^- 50kD endoglucanase from Humicola insolens DSM 1800 or it is ^- 50kD endoglucan that exhibits cellulase activity Homologue or derivative of enzyme; Preferred endoglucanase component has the disclosed aminoacid sequence among the PCT patent application WO91/17244, or endoglucanase component, it and by Fusarium oxysporum (Fusarium oxysporum) DSM 2672 obtained high purity ^- 50kD (apparent molecular weight, amino acid composition is equivalent to 45kD with 2n glycosylation site) endoglucanase immunoreaction or it shows cellulase activity Homologs or derivatives of ^-50 kD endoglucanase; preferred endoglucanase components have the amino acid sequence disclosed in PCT patent application WO91/17244. More preferred is obtained from Humicola insolens, DSM1800, which has an approximate molecular weight of about 50 kDa, an isoelectric point of about 5.5, and contains 415 amino acids.

Endoglucanases can be obtained from microorganisms known to produce cellulolytic enzymes, such as Humicola, Bacillus, Trichederma, Fusarium, Myceliophtora, Phanerochaete, Schizophyllum ), Penicillium, Aspergillus and Geotricum were obtained or isolated, and purified. The resulting components may be homologous or heterogeneous, preferably the components are homogeneous. However, heterologous fractions immunoreactive with antibodies produced by highly pure cellulase fractions having the desired properties, and heterologous fractions derived from specific microorganisms are also preferred.

For example, as described in WO95/02675, another suitable endoglucanase component has SEQ ID NO: 2 attached therein or the amino acid sequence disclosed in WO91/17244, accompanying drawings 14A-E or has Said endoglucanase variant with an amino acid sequence at least 60%, preferably at least 70%, more preferably at least 75%, more preferably at least 80%, more preferably at least 85%, especially at least 90% homologous to said sequence .

The endoglucanase can also be an endoglucanase obtained from Fusarium oxysporum (Fusarium oxysporum) DSM 2672 with high purity ^- 50kD (apparent molecular weight, amino acid composition is equivalent to 45kD with 2n glycosylation sites). The glucanase-generated antibody is immunoreactive to the endoglucanase component or it is a homologue or derivative of the ^-50kD endoglucanase exhibiting cellulase activity. A preferred endoglucanase component has SEQ ID NO: 3 attached in WO95/02675 or the amino acid sequence disclosed in WO91/17244, accompanying drawing 13 or has at least 60%, preferably at least 70%, more preferably 75%, more preferably at least 80%, more preferably 85%, especially at least 90% homologous amino acid sequence to said endoglucanase variant.

Described endoglucanase component component is made by Aspergillus oryzae (Aspergillus oryzae) with the plasmid containing the DNA sequence corresponding to the aminoacid sequence described in WO95/02675 SEQ ID NO: 3 and using Taka promoter and AMG Prepared after conversion of the terminator, the endoglucanase can be purified to homogeneity with pl > 9 by cationic chromatography. The calculated pl was based on the amino acid composition and using the PHKa value from Adv. Protein Chem. 17, pp. 69-165 (1962), C. Tanford. The molar extinction coefficient was calculated as 58180.

Other suitable cellulases are EGIII from Trichoderma longibrachiatum described in WO 94/21801, Genencor, published September 29, 1994. A more preferred cellulase for use in the laundry detergent compositions of the present invention is obtained from Trichoderma spp having an approximate molecular weight of 22-27 kDa, an isoelectric point of 7.2-8.0 and a pH optimum of 5.5-6.0 of cellulase.

In the present invention, the term "homologous" refers to a polypeptide encoded by DNA, which is prepared under certain special conditions (such as presoaking in 5×SSC and in 20% formamide, 5×Denhardt's solution, 50 mM sodium phosphate, pH6 .8 and 50 μg of denatured sonicated calf thymus DNA were prehybridized at about 40° C. for 1 hour, followed by hybridization at about 40° C. in the same solution supplemented with 100 μM ATP) for 18 hours) which is compatible with the endogenous DNA encoded by the amino acid sequence Hybridize with the same probe as the DNA that cleaves the glucanase. The term includes addition of one or more amino acid residues at one or both of the C- and N-termini of the native sequence, substitution of one or more amino acid residues at one or more positions in the native sequence, Derivation of the above sequence obtained by deleting one or more amino acid residues at one or both ends of the natural sequence or at one or more positions in the natural sequence or inserting one or more amino acid residues at one or more positions in the natural amino acid sequence thing.

However, for the industrial production of cellulase preparations it is preferred to employ recombinant DNA techniques or other techniques involving modulation of fermentation or involving mutation of microorganisms to ensure overproduction of the desired enzyme activity. Such methods and techniques are known in the art and can be readily performed by those skilled in the art.

The aforementioned enzymes may be of any suitable origin, such as vegetable, animal, bacterial, fungal and yeast origin. The source can also be mesophilic or extremophilic (psychrophilic, thermophilic, barophilic, basophilic, acidophilic, halophilic, etc.). Pure or impure forms of these enzymes can be used. Currently, it is common practice to modify wild-type enzymes via protein/genetic engineering techniques to optimize their performance efficiency in the detergent compositions of the present invention. For example, variants can be designed to increase the compatibility of the enzyme with commonly encountered components of the composition. In addition, variants can be designed such that the optimal pH, bleach or chelator stability, catalytic activity etc. of the enzyme variant can be tailored to a specific wash application.

Particular attention should be paid to oxidation-sensitive amino acids in the case of bleach stability, and to the surface charge for surfactant compatibility. The isoelectric point of this enzyme can be modified by the substitution of some charged amino acids, for example, increasing the isoelectric point will help to improve the compatibility with anionic surfactants. Enzyme stability can be further improved by creating, for example, additional salt bridges and strengthening calcium binding sites to increase chelator stability. Glucoside Surfactants:

Detergent composition of the present invention contains following formula alkyl polyglucoside surfactant:

ROG _x wherein R is an average C ₈ -C ₂₀ , preferably C ₈ -C ₁₆ alkyl, G is a moiety derived from a reducing sugar containing 5-6 carbon atoms, preferably a glucose unit, x is an average of 1.0-3.0, Preferably about 1.1-1.5, representing the average degree of polymerization of the alkyl polysaccharide surfactant.

For a particular alkylpolysaccharide molecule, x can only assume integer values. In any physical sample of alkyl polyglucoside surfactants, they are usually molecules with different values of x. Physical samples can be characterized by x-means, which can assume non-integer values. In the specification, the value of x is considered to be an average value.

The polysaccharide hydrophilic part of the surfactant contains an average of about 1 to about 3, preferably 1.1 to about 1.5 carbohydrate units, which can be galactoside, glucoside, lactoside, fructoside, glucosyl, fructosyl , lactosyl and/or galactosyl units. Mixtures of these carbohydrate moieties can be used in the alkyl polysaccharide surfactants. Glucosides are the preferred carbohydrate moieties. Other carbohydrate moieties will work equally well, but since glucoside is the preferred carbohydrate moiety, the remainder of the disclosure will focus on alkyl polyglucoside surfactants.

The hydrophobic group of the alkylpolysaccharide is the alkyl group, which is saturated or unsaturated, branched or unbranched, containing an average of about 10 to about 16 carbon atoms. Preferred alkyl groups are predominantly linear saturated C ₁₂ -C ₁₄ alkyl groups.

Also useful as nonionic surfactants in the surfactant system of the present invention are the alkylpolysaccharides disclosed in US4565647, Llenado, issued January 21, 1986, having carbon atoms of about 6 to about 30, Hydrophobic groups of from about 10 to about 16 carbon atoms are preferred and polysaccharides containing from about 1.3 to about 10, preferably from about 1.3 to about 3, most preferably from about 1.3 to about 2.7 saccharide units, such as polyglycoside hydrophilic groups. Any reducing sugar containing 5 or 6 carbon atoms can be used, such as glucose, galactose and galactosyl moieties can be used in place of glucosyl moieties (hydrophobic groups are selectively attached at 2-, 3-, 4-, etc. , so as to obtain glucose or galactose relative to glucoside or galactoside). Intersaccharide linkages may be, for example, between one position of the additional sugar unit and the 2-, 3-, 4- and/or 6-position of the previous sugar unit.

Preferred alkyl polyglycosides have the formula:

R ² O(C _n H _2n O) _t (glycosyl) _x wherein R ² is selected from the group consisting of alkyl, alkylphenyl, hydroxyalkyl, hydroxyalkylphenyl and mixtures thereof, wherein the alkyl group contains about 10- About 18, preferably about 12 to about 14 carbon atoms; n is 2 or 3, preferably 2; t is 0 to about 10, preferably 0; and x is about 1.3 to about 10, preferably about 1.3 to about 3, most preferably About 1.3-about 2.7. The glycosyl is preferably derived from glucose. To prepare these compounds, the alcohol or alkyl polyethoxy alcohol is first formed and subsequently reacted with glucose or a source of glucose to form the glucoside (attached at the 1-position). Further glycosyl units may subsequently be attached between their 1-position and the previous glycosyl unit 2-, 3-, 4- and/or 6-position, preferably predominantly in the 2-position.

Preferred alkyl polyglucoside surfactants contain a hydrophilic group comprising 1-6, preferably 2-4 alpha or beta pyranoside or furanoside anomers.

The alkyl polyglucoside surfactant is included in the detergent composition of the present invention at a level of 0.1-20%, preferably 1-10%, more preferably 2-8% by weight of the total composition. detergent components

The laundry detergent compositions of the present invention may also contain other detergent ingredients. The exact nature of these additional ingredients and their level of addition will depend upon the physical form of the composition and the nature of the laundering operation employed.

The cleaning composition of the present invention can be in the form of liquid, paste, gel, block, tablet, spray, foam, powder or granules, the granular composition can also be in the form of "compact", and the liquid composition can also be in the form of "concentrated" form.

The compositions of the present invention may be formulated, for example, as hand and machine laundry detergent compositions comprising laundry additive compositions and compositions suitable for soaking and/or pretreatment of soiled fabrics, rinse added fabric softener compositions.

The compositions of the present invention preferably contain both surfactant and builder compounds and additional one or more detergent ingredients, preferably selected from the group consisting of organic polymers, bleaching agents, additional enzymes, suds suppressors, dispersing agent, lime soap dispersant, soil suspending agent and anti-redeposition agent and corrosion inhibitor. Laundry compositions can also contain softening agents as additional detergent ingredients.

When formulated into a laundry detergent composition, the composition containing said specific cellulase and an alkyl polyglucoside surfactant provides fabric cleaning, stain removal, whiteness maintenance, softness, color appearance, dye transfer inhibition and hygienic effects.

The compositions of the present invention are also useful as detergent additive products. The additive products are used to supplement or enhance the performance of conventional detergent compositions.

If desired, the laundry detergent compositions of the present invention have a density, measured at 20°C, of 400-1200 g/l, preferably 600-950 g/l composition.

The "compact" form of the compositions of the present invention is best reflected by the density and, for the composition, by the amount of inorganic filler salt; inorganic filler salt is a conventional component of detergent compositions in powder form; in conventional detergent compositions In , the filler salt is present in substantial amounts, typically 17-35% by weight of the total composition.

In compact compositions, the filler salt is present in an amount not exceeding 15%, preferably not exceeding 10%, most preferably not exceeding 5% by weight of the composition of the total composition.

The inorganic filler salts as described in the composition of the present invention are selected from alkali metal and alkaline earth metal sulfates and chlorides.

A preferred filler salt is sodium sulfate.

The liquid detergent compositions of the present invention may also be in "concentrated" form, in which case the liquid detergent compositions of the present invention will contain lower levels of water compared to conventional liquid detergents.

Concentrated liquid detergents generally preferably have a water content of less than 40%, more preferably less than 30%, most preferably less than 20% by weight of the detergent composition. Additional Surfactant System

The laundry detergent compositions of the present invention generally contain a surfactant system in addition to the alkyl polyglucoside surfactant, wherein the surfactant may be selected from other nonionic and/or anionic and/or cationic and/or amphoteric and /or zwitterionic and/or semi-polar surfactants.

Surfactants are typically present in amounts of 0.1% to 60% by weight. In the laundry and rinse softener composition of the present invention, it is more preferably added in an amount of 1%-35% by weight, most preferably 1%-25% by weight.

The surfactant is preferably formulated to be compatible with the enzyme components present in the composition. In liquid or gel compositions, the surfactant is most preferably formulated so as to promote, or at least not destabilize, any enzymes present in these compositions.

Preferred surfactant systems for use in the present invention contain one or more nonionic and/or anionic surfactants described herein as surfactants.

Polyoxyethylene, polyoxypropylene and polyoxybutylene condensates of alkylphenols are suitable as nonionic surfactants in the surfactant system according to the invention, polyoxyethylene condensates being preferred. These compounds include the condensation products of alkylphenols with alkylene oxides having an alkyl group of about 6 to about 14 carbon atoms, preferably about 8 to about 14 carbon atoms, in a linear or branched configuration. In a preferred embodiment, ethylene oxide is present in an amount equal to about 2 to about 25 moles, more preferably about 3 to about 15 moles of ethylene oxide per mole of alkylphenol. Commercially available nonionic surfactants of this type include Igepal ^™ CO-630 sold by GAF Corporation, Triton ^™ X-45, X-114, X-100 and X-102 sold by Rohm & Haas Corporation. These surfactants are commonly referred to as alkylphenol alkoxylates (eg, alkylphenol ethoxylates).

The condensation products of primary and secondary aliphatic alcohols with from about 1 to about 25 moles of ethylene oxide are suitable for use as the nonionic surfactant of the nonionic surfactant system of the present invention. The alkyl chain of the aliphatic alcohol can be straight or branched, primary or secondary, and generally contains from about 8 to about 22 carbon atoms. Preferred are the condensation products of alcohols having alkyl groups containing from about 8 to about 20 carbon atoms, more preferably from about 10 to about 18 carbon atoms, with about 2 to about 10 moles of ethylene oxide per mole of alcohol. From about 2 to about 7 moles of ethylene oxide, most preferably from 2 to 5 moles of ethylene oxide, are present in the condensation product per mole of alcohol. Examples of commercially available nonionic surfactants of this type include Tergitol ^™ 15-S-9 (a condensation product of C ₁₁ -C ₁₅ linear alcohols with 9 moles of ethylene oxide), Tergitol ^™ 24-L -6 NMW (condensation products of C ₁₂ -C ₁₄ primary alcohols with narrow molecular weight distribution and 6 moles of ethylene oxide), both sold by Union Carbide; Neodol ^TM 45-9 (C ₁₄ -C ₁₅ linear alcohols with Condensation product of 9 moles of ethylene oxide), Neodol ^TM 23-3 (condensation product of C ₁₂ -C ₁₃ straight chain alcohol and 3.0 moles of ethylene oxide), Neodol ^TM 45-7 (C ₁₄ -C ₁₅ straight chain Alcohol Condensation Product with 7 Moles of Ethylene Oxide), Neodol ^TM 45-5 (Condensation Product of C ₁₄ -C ₁₅ Linear Alcohols with 5 Moles of Ethylene Oxide), both sold by Shell Chemical Company, Kyro ^TM EOB ( Condensation product of C ₁₃ -C ₁₅ alcohol with 9 moles of ethylene oxide), sold by the company Procter &Gamble; and Genapol LA 030 or 050 (condensation product of C ₁₂ -C ₁₄ alcohol with 3 or 5 moles of ethylene oxide ), marketed by Hoechst. The preferred HLB range for these products is 8-11, most preferably 8-10.

Condensation products of ethylene oxide with hydrophobic groups formed by condensation of propylene oxide with propylene glycol are also suitable for use as an additional nonionic surfactant system in the present invention. The hydrophobic portion of these compounds preferably has a molecular weight of from about 1500 to about 1800 and exhibits water insolubility. The addition of polyoxyethylene groups to this hydrophobic moiety will increase the overall water solubility of the molecule and the liquid character of the product will remain until the polyoxyethylene content is about 50% of the total weight of the condensation product, which corresponds to condensation of up to about 40 moles of Ethylene oxide. Examples of compounds of this type include certain of the commercially available Plurafac ^™ LF404 and Pluronic ^™ surfactants, both sold by BASF.

Also suitable for use as the nonionic surfactant of the nonionic surfactant system according to the invention are the condensation products of ethylene oxide with the product obtained by reacting propylene oxide and ethylenediamine. The hydrophobic groups of these products consist of the reaction product of ethylenediamine and excess propylene oxide and generally have a molecular weight of from about 2500 to about 3000. The hydrophobic group is condensed with ethylene oxide to such an extent that the condensation product contains from about 40% to about 80% by weight polyoxyethylene and has a molecular weight of from about 5,000 to about 11,000. Examples of nonionic surfactants of this type include certain of the commercially available Tetronic ^™ compounds, marketed by BASF.

Preferred nonionic surfactants for use in the surfactant system of the present invention are polyethylene oxide condensates of alkylphenols, condensation products of primary and secondary aliphatic alcohols with from about 1 to about 25 moles of ethylene oxide, Alkyl polysaccharides and their mixtures. Most preferred are _C8 - _C14 alkylphenol ethoxylates containing 3-15 ethoxy groups and _C8 - _C18 alcohol ethoxylates containing 2-10 ethoxy groups (preferably _C10 average) and their mixture.

Highly preferred nonionic surfactants are polyhydroxy fatty acid amide surfactants of the formula:

R ² -C(O)-N(R ¹ )-Z wherein R ¹ is H, or R ¹ is C _1-4 hydrocarbon group, 2-hydroxyethyl, 2-hydroxypropyl or a mixture thereof, R ² is _C5-31 hydrocarbyl, and Z is a polyhydroxyhydrocarbyl having a linear hydrocarbyl chain directly attached to at least 3 hydroxyl groups, or an alkoxylated derivative thereof. Preferably ^R is methyl, ^R is a straight C _11-15 alkyl or C _16-18 alkyl or alkenyl chain, such as coconut oil alkyl or mixtures thereof, and Z is formed from a reducing sugar such as glucose, Fructose, maltose, and lactose are obtained in reductive amination reactions.

Suitable anionic surfactants that can be used are linear alkylbenzene sulfonate, alkyl ester sulfonate surfactants, which include linear esters of C ₈ -C ₂₀ carboxylic acids (i.e. fatty acids) according to " Sulfonation with gaseous sulfur trioxide by the method in Journal of the American Oil Chemists' Society, 52 (1975) pp. 323-329. Suitable materials would include natural fatty materials derived from tallow, palm oil, and the like.

Preferred alkyl ester sulfonate surfactants, especially for laundry applications, include alkyl ester sulfonate surfactants of the formula:

R ³ -CH(SO ₃ M)-C(O)-OR ⁴ wherein R ³ is a C ₈ -C ₂₀ hydrocarbon group, preferably an alkyl group or a combination thereof, R ⁴ is a C ₁ -C ₆ hydrocarbon group, preferably an alkyl group or Their combination, M is a cation, which forms a water-soluble salt with an alkyl ester sulfonic acid. Suitable salt-forming cations include metals such as sodium, potassium and lithium, and substituted or unsubstituted ammonium cations such as monoethanolamine, diethanolamine and triethanolamine. Preferably R ³ is C ₁₀ -C ₁₆ alkyl, and R ⁴ is methyl, ethyl or isopropyl. Especially preferred are methyl ester sulfonates wherein R ³ is C ₁₀ -C ₁₆ alkyl.

Other suitable anionic surfactants include alkyl sulfate surfactants which are water soluble salts or acids of the formula ROSO ₃ M wherein R is preferably a C ₁₀ -C ₂₄ hydrocarbyl, preferably containing a C ₁₀ -C ₂₀ alkyl moiety Alkyl or hydroxyalkyl, more preferably C ₁₂ -C ₁₈ alkyl or hydroxyalkyl, M is H or a cation, which can be an alkali metal cation (e.g. sodium, potassium, lithium), or ammonium or substituted ammonium ( Methyl-, dimethyl- and trimethyl-ammonium cations and quaternary ammonium cations such as tetramethylammonium and dimethylpiperidinium cations and alkylamines such as ethylamine, diethylamine, triethylamine obtained quaternary ammonium cations and mixtures thereof, etc.). _C12 - _C16 alkyl chains are generally preferred for low wash temperatures (eg, below about 50°C), and _C16-18 alkyl chains are preferred for higher wash temperatures (eg, above about 50°C).

Other anionic surfactants suitable for detersive use may also be included in the detergent compositions of the present invention. They may include soap salts (including, for example, sodium, potassium, ammonium and substituted ammonium salts such as mono-, di- and triethanolamine salts), C ₈ -C ₂₂ primary or secondary alkane sulfonates, C ₈ -C ₂₄ Olefin sulfonates, sulfonated polycarboxylic acids prepared by sulfonating pyrolysis products of alkaline earth metal citrates described in GB1082179, C ₈ -C ₂₄ alkyl polyglycol ether sulfates (containing up to 10 moles of ring ethylene oxide); alkyl glycerol sulfonates, fatty acyl glycerol sulfonates, fatty oleoyl glycerol sulfates, alkylphenol oxirane ether sulfates, paraffin sulfonates, alkyl phosphates, hydroxyethyl Sulfonates, for example, acyl isethionates, N-acyl taurates, alkyl succinamates and sulfosuccinates, sulfosuccinate monoesters (especially saturated and unsaturated _C12 -C ₁₈ monoesters) and sulfosuccinate diesters (especially saturated and unsaturated C ₆ -C ₁₂ diesters), acyl sarcosinates, sulfates of alkyl polysaccharides, such as alkyl polyglucoside sulfates Salts (nonionic _unsulfated compounds described below), branched primary alkyl sulfates and alkyl polyethoxy carboxylates, such as the formula RO( _CH2CH2O ) _k - _CH2COO ^- M ⁺ wherein, R is a C ₈ -C ₂₂ alkyl group, k is an integer of 1-10, and M is a water-soluble salt-forming cation. Resin acids and hydrogenated resin acids are also suitable, such as rosin, hydrogenated rosin, and resin acids and hydrogenated resin acids present in or derived from tall oil.

Further examples are described in "Surface Active Agents and Detergents" (Volumes I and II, Schwartz, Perry and Berch). A variety of such surfactants are also generally described in US Patent 3,929,678, Laughlin et al., issued December 30, 1975, column 23, line 58 through column 29, line 23 (herein incorporated by reference).

If included, the laundry detergent compositions of the present invention will generally contain from about 1% to about 40%, preferably from about 3% to about 20%, by weight of such anionic surfactants.

Highly preferred anionic surfactants including alkyl alkoxylated sulfate surfactants are water soluble salts or acids of the formula RO(A) _m SO ₃ M where R is an unsubstituted C ₁₀ -C ₂₄ alkyl Or hydroxyalkyl containing C ₁₀ -C ₂₄ alkyl moiety, preferably C ₁₂ -C ₂₀ alkyl or hydroxyalkyl, more preferably C ₁₂ -C ₁₈ alkyl or hydroxyalkyl, A is ethoxy or propoxy m is greater than zero, usually between about 0.5 and about 6, more preferably between about 0.5 and about 3, M is H or a cation, which can be, for example, a metal cation (e.g., sodium, potassium, lithium, calcium, magnesium, etc.), ammonium or substituted ammonium cations. The present invention contemplates both alkyl ethoxylated sulfates and alkyl propoxylated sulfates. Specific examples of substituted ammonium cations include methyl-, dimethyl-, trimethyl-ammonium cations, and quaternary ammonium cations such as tetramethylammonium and dimethylpiperidinium cations and those derived from alkylamines such as ethylamine , diethylamine, triethylamine, their mixtures, etc. to obtain cations, etc. Exemplary surfactants are C ₁₂ -C ₁₈ alkyl polyethoxylate (1.0) sulfate (C ₁₂ -C ₁₈ E(1.0)M), C ₁₂ -C ₁₈ alkyl polyethoxylate ( 2.25) Sulfate (C ₁₂ -C ₁₈ E(2.25)M), C ₁₂ -C ₁₈ Alkyl Polyethoxylate (3.0) Sulfate (C ₁₂ -C ₁₈ E(3.0)M) and C ₁₂ - C ₁₈ alkyl polyethoxylate (4.0) sulfate (C ₁₂ -C ₁₈ E(4.0)M), where M is typically selected from sodium and potassium.

The detergent compositions of the present invention may also contain cationic, amphoteric, zwitterionic and semi-polar surfactants as well as nonionic and/or anionic surfactants other than those already described above.

Cationic detersive surfactants suitable for use in the detergent compositions herein are those which contain a long chain hydrocarbyl group. Examples of the cationic surfactant include ammonium surfactants, such as alkyltrimethylammonium halides, and surfactants having the formula:

[R ² (OR ³ ) _y ][R ⁴ (OR ³ ) _y ] ₂ R ⁵ N ⁺ X ^- wherein R ² is an alkyl or alkyl benzyl having from about 8 to about 18 carbon atoms in the alkyl chain Each R ³ is selected from the group consisting of -CH ₂ CH ₂ -, -CH ₂ CH(CH ₃ )-, -CH ₂ CH(CH ₂ OH)-, -CH ₂ CH ₂ CH ₂ - and mixtures thereof; Each R ⁴ is selected from C ₁ -C ₄ alkyl, C ₁ -C ₄ hydroxyalkyl, benzyl ring structure formed by connecting two R ⁴ groups, -CH ₂ CHOH-CHOHCOR ⁶ CHOHCH ₂ OH, wherein R ⁶ is any hexose or hexose polymer having a molecular weight of less than about 1000, and when y is other than 0, hydrogen; ^R is the same as ^R or wherein the total number of carbon atoms in R ^{plus R} does not exceed about 18 an alkyl chain; each y is from 0 to about 10, the sum of the values of y is from 0 to about 15; and X is any compatible anion.

The quaternary ammonium surfactant suitable for use in the present invention has the following formula (I):

Formula I wherein R is a short-chain alkyl group (C6-C10) or an alkylamidoalkyl group of the following formula (II):

Formula IIy is 2-4, preferably 3, wherein R2 is H or C1-C3 alkyl, wherein x is 0-4, preferably 0-2, most preferably 0, wherein R3, R4 and R5 are identical or different, can is a short chain alkyl group (C1-C3) or an alkoxylated alkyl group of the following formula III, wherein X ^- is a counterion, preferably a halide, such as chloride or methylsulfate,

Formula IIIR6 is C ₁ -C ₄ and z is 1 or 2.

Preferred quaternary ammonium surfactants are compounds defined by formula I, wherein R ₁ is C ₈ , C ₁₀ or mixtures thereof, x=0, R ₃ , R ₄ =CH ₃ and R ₅ =CH ₂ CH ₂ OH .

Highly preferred cationic surfactants for use in the compositions of the present invention are water-soluble quaternary ammonium compounds having the formula:

R ₁ R ₂ R ₃ R ₄ N ⁺ X ^- (i) wherein R ₁ is C ₈ -C ₁₆ alkyl, each of R ₂ , R ₃ and R ₄ is C ₁ -C ₄ alkyl, C ₁ - C ₄ hydroxyalkyl, benzyl, and -(C ₂ H ₄ O) _x H, where x is 2-5 and X is an anion. Not more than one of _R2 , _R3 or _R4 shall be benzyl.

Preferred alkyl chain lengths for R ₁ are C ₁₂ -C ₁₅ , especially mixtures of chain lengths where the alkyl group is derived from coconut oil or palm kernel fat or from olefin synthesis or OXO alcohol synthesis. Preferred groups for R ₂ , R ₃ and R ₄ are methyl and hydroxyethyl, and the anion X may be selected from halide, methylsulfate, acetate and phosphate ions.

Examples of suitable quaternary ammonium compounds of formula (i) for use in the present invention include: cocotrimethylammonium chloride or bromide; cocomethyldihydroxyethylammonium chloride or bromide; decyltriethylammonium chloride or bromide; Ammonium Chloride; Decyl Dimethyl Hydroxyethyl Ammonium Chloride or Bromide; C _12-15 Dimethyl Hydroxyethyl Ammonium Chloride or Bromide; Coco Dimethyl Hydroxyethyl Ammonium Chloride or Bromide ; tetradecyl trimethyl ammonium methyl sulfate; dodecyl dimethyl benzyl ammonium chloride or bromide; dodecyl dimethyl (oxyethylene) ₄ ammonium chloride or bromide; Choline esters (compounds of formula (i) wherein R ₁ is CH ₂ -CH ₂ -OC(O)-C _12-14 alkyl and R ₂ , R ₃ and R ₄ are methyl); dialkylimidazolines [compound of formula (i)].

Other cationic surfactants useful in the present invention are also described in US Patent 4,228,044 and EP 000224, Cambre, issued October 14,1980.

Typical cationic fabric softening ingredients include water insoluble quaternary ammonium fabric softening actives, most commonly dilong alkyl chain ammonium chloride or methylsulfate.

Wherein preferred cationic softener includes as follows:

1) ditallow dimethyl ammonium chloride (DTDMAC);

2) dihydrogenated tallow dimethyl ammonium chloride;

3) dihydrogenated tallow dimethyl ammonium methyl sulfate;

4) distearyl dimethyl ammonium chloride;

5) dioleyl dimethyl ammonium chloride;

6) dipalmityl hydroxyethyl methyl ammonium chloride;

7) stearyl benzyl dimethyl ammonium chloride;

8) tallow trimethylammonium chloride;

9) Hydrogenated tallow trimethylammonium chloride;

10) C _12-14 alkyl hydroxyethyl dimethyl ammonium chloride;

11) C _12-18 alkyl dihydroxyethyl methyl ammonium chloride;

12) Di(stearyloxyethyl)dimethylammonium chloride (DSOEDMAC);

13) Di(tallowoxyethyl) dimethyl ammonium chloride;

14) Ditallow imidazolium methyl sulfate;

15) 1-(2-Tallowamidoethyl)-2-tallowimidazolium methylsulfate.

Biodegradable quaternary ammonium compounds have been used as replacements for commonly used dilong alkyl chain ammonium chloride and methylsulfate. The quaternary ammonium compounds contain long chain alk(en)yl groups interrupted by functional groups such as carboxyl groups, said materials and fabric softening compositions containing them are disclosed in a number of publications such as EP-A-0040562 and EP-A-0239910 .

其中Q选自-O-C(O)-、-C(O)-O-、-O-C(O)-O-、-NR⁴-C(O)-、-C(O)-NR⁴-；R¹是(CH₂)_n-Q-T²或T³；R²是(CH₂)_m-Q-T⁴或T⁵或R³；R³是C₁-C₄烷基或C₁-C₄羟基烷基或H；R⁴是H或C₁-C₄烷基或C₁-C₄羟基烷基；T¹、T²、T³、T⁴和T⁵独立地是C₁₁-C₂₂烷基或烯基；n和m是1-4的整数；和X^-是柔软剂相容的阴离子。The quaternary ammonium compounds and amine precursors of the present invention have the following formula (I) or (II):

Wherein Q is selected from -OC(O)-, -C(O)-O-, -OC(O)-O-, -NR ⁴ -C(O)-, -C(O)-NR ⁴ -; R ¹ is (CH ₂ ) _n -QT ² or T ³ ; R ² is (CH ₂ ) _m -QT ⁴ or T ⁵ or R ³ ; R ³ is C ₁ -C ₄ alkyl or C ₁ -C ₄ hydroxyalkane radical or H; R ⁴ is H or C ₁ -C ₄ alkyl or C ₁ -C ₄ hydroxyalkyl; T ¹ , T ² , T ³ , T ⁴ and T ⁵ are independently C ₁₁ -C ₂₂ alkyl Or alkenyl; n and m are integers from 1 to 4; and X ^- is a softener compatible anion.

Non-limiting examples of softener compatible anions include chloride or methylsulfate.

The alkyl or alkenyl chains T ¹ , T ² , T ³ , T ⁴ and T ⁵ must contain at least 11 carbon atoms, preferably at least 16 carbon atoms. Chains can be straight or branched.

Tallow is a convenient and inexpensive source of long chain alkyl and alkenyl species. Compounds in which T ¹ , T ² , T ³ , T ⁴ and T ⁵ represent mixtures of long-chain species, usually tallow, are especially preferred.

Specific examples of quaternary ammonium compounds suitable for use in the aqueous fabric softening compositions of the present invention include: 1) N,N-bis(tallowyloxyethyl)-N,N-dimethylammonium chloride; 2) N , N-bis(tallowyloxyethyl) N-methyl, N-(2-hydroxyethyl) methyl sulfate; 3) N, N-bis(2-tallowyloxy-2- Oxoethyl)-N,N-dimethylammonium chloride; 4) N,N-di(2-tallowyloxy-ethylcarbonyl-oxyethyl)-N,N-dimethyl Ammonium chloride; 5) N-(2-tallowyloxy-2-ethyl)-N-(2-tallowyloxy-2-oxoethyl)-N,N-dimethyl chloride Ammonium chloride; 6) N,N,N-tris(tallowyl-oxyl-ethyl)-N-methylammonium chloride; 7) N-(2-tallowyl-amino-2-oxoethyl base)-N-(tallowyl)-N,N-dimethylammonium chloride; and 8) 1,2-ditallowyloxy-3-trimethylammoniumpropane chloride; and any of the foregoing mixture.

If included, the detergent compositions herein will generally contain from 0.2% to about 25%, preferably from about 1% to about 8%, by weight of such cationic surfactants.

Amphoteric surfactants are also suitable for use in the detergent compositions of the present invention. These surfactants can be broadly described as aliphatic derivatives of secondary or tertiary amines or aliphatic derivatives of heterocyclic secondary and tertiary amines, wherein the aliphatic group may be straight or branched. One of the aliphatic substituents contains at least about 8 carbon atoms, usually from about 8 to about 18 carbon atoms and at least one of the aliphatic substituents contains an anionic water solubilizing group, eg, carboxy, sulfonate, sulfate. See US Patent 3,929,678, Laughlin et al., issued December 30, 1975, column 19, lines 18-35, for examples of amphoteric surfactants.

If included, the detergent compositions herein will generally contain from 0.2% to about 15%, preferably from about 1% to about 10%, by weight of such amphoteric surfactants.

Zwitterionic surfactants are also suitable for use in the detergent compositions of the present invention. These surfactants can be broadly described as derivatives of secondary and tertiary amines, derivatives of heterocyclic secondary and tertiary amines, or derivatives of quaternary ammonium, quaternary phosphonium or tertiary sulfonium compounds. See US Patent 3,929,678, Laughlin et al., issued December 30, 1975, column 19, line 38-column 22, line 48, for examples of zwitterionic surfactants.

If included, the detergent compositions herein will generally contain from 0.2% to about 15%, preferably from about 1% to about 10%, by weight of such zwitterionic surfactants.

Semi-polar nonionic surfactants are a special class of nonionic surfactants that include an alkyl moiety containing about 10 to about 18 carbon atoms and two alkyl moieties selected from the group consisting of about 1 to about 3 carbon atoms A water-soluble amine oxide containing part of an alkyl group and a hydroxyalkyl group; containing one alkyl group of about 10 to about 18 carbon atoms and two moieties selected from the group consisting of an alkyl group and a hydroxyalkyl group of about 1 to about 3 carbon atoms water-soluble phosphine oxides; and water-soluble sulfoxides containing an alkyl moiety of about 10 to about 18 carbon atoms and a moiety selected from the group consisting of alkyl and hydroxyalkyl groups of about 1 to about 3 carbon atoms.

Semi-polar nonionic detergent surfactants include amine oxide surfactants having the formula: wherein ^R3 is alkyl, hydroxyalkyl or alkylphenyl or a mixture thereof containing about 8 to about 22 carbon atoms; ^R4 is alkylene or hydroxyalkylene containing about 2 to about 3 carbon atoms or mixtures thereof; x is 0 to about 3; each ^R is an alkyl or hydroxyalkyl group containing about 1 to about 3 carbon atoms or a polyoxygen group containing about 1 to about 3 oxirane groups Vinyl group. The R ⁵ groups may be linked to each other, for example via an oxygen or nitrogen atom, to form a ring structure.

These amine oxide surfactants include C ₁₀ -C ₁₈ alkyl dimethyl amine oxides and C ₈ -C ₁₂ alkoxyethyl dihydroxyethyl amine oxides, among others.

If included, the detergent compositions herein will generally contain from 0.2% to about 15%, preferably from about 1% to about 10%, by weight of semi-polar nonionic surfactants.

The detergent compositions of the present invention also contain cosurfactants selected from primary or tertiary amines. Suitable primary amines for use in the present invention include amines of formula R ₁ NH ₂ , wherein R ₁ is a C ₆ -C ₁₂ , preferably C ₆ -C ₁₀ alkyl chain or R ₄ X(CH ₂ ) _n , x is - O-, -C(O)NH- or -NH-, R ₄ is a C ₆ -C ₁₂ alkyl chain, n is 1 to 5, preferably 3. The R ₁ alkyl chain may be straight or branched and may be interrupted by up to 12, preferably less than 5, ethylene oxide moieties.

Preferred amines of the above formula according to the invention are n-alkylamines. Suitable amines for use in the present invention are selected from 1-hexylamine, 1-octylamine, 1-decane and dodecylamine. Other preferred primary amines include C ₈ -C ₁₀ oxypropylamine, octyloxypropylamine, 2-ethylhexyloxypropylamine, dodecylamidopropylamine and amidopropylamine.

R₃是C₆-C₁₂，优选C₆-C₁₀烷基链或R₃是R₄X(CH₂)_n，而X是-O-、-C(O)NH-或-NH-，R₄是C₄-C₁₂，n是1至5，优选是2-3。R₅是H或C₁-C₂烷基和x是1-6。Suitable tertiary amines for use in the present invention include tertiary amines having the formula R ₁ R ₂ R ₃ N, wherein R ₁ and R ₂ are C ₁ -C ₈ alkyl chains or

R ₃ is C ₆ -C ₁₂ , preferably a C ₆ -C ₁₀ alkyl chain or R ₃ is R ₄ X(CH ₂ ) _n , and X is -O-, -C(O)NH- or -NH-, R ₄ is C ₄ -C ₁₂ , n is 1 to 5, preferably 2-3. R ₅ is H or C ₁ -C ₂ alkyl and x is 1-6.

_R3 and _R4 may be linear or branched; the _R3 alkyl chain may be interrupted by up to 12, preferably less than 5, oxirane moieties.

其中R₅是H或甲基和x＝1-2。Preferred tertiary amines are R ₁ R ₂ R ₃ N, wherein R ₁ is a C ₆ -C ₁₂ alkyl chain, R ₂ and R ₃ are C ₁ -C ₃ alkyl or

wherein R ₅ is H or methyl and x=1-2.

Also preferred are amidoamines of the formula: Wherein R ₁ is C ₆ -C ₁₂ alkyl; n is 2-4, preferably n is 3; R ₂ and R ₃ are C ₁ -C ₄ .

The most preferred amines of the present invention include 1-octylamine, 1-hexylamine, 1-decylamine, 1-dodecylamine, _C8 - _C10 oxypropylamine, N-coco 1-3 diaminopropane, Coco Dimethylamine, Lauryl Dimethylamine, Dodecyl Di(Hydroxyethyl)amine, Coco Di(Hydroxyethyl)amine, 2 Moles Propoxylated Dodecylamine , 2 moles of propoxylated octylamine, lauryl amidopropyl dimethylamine, C _8-10 amidopropyl dimethylamine and C ₁₀ amidopropyl dimethylamine.

The most preferred amines for use in the compositions of the present invention are 1-hexylamine, 1-octylamine, 1-decane, 1-dodecylamine. Particularly desirable are n-dodecyldimethylamine and dihydroxyethylcocoalkylamine and 7-times ethoxylated oleylamine, dodecylamidopropylamine and cocoamidopropylamine. Regular Detergent Enzyme

Laundry detergent compositions may contain, in addition to the specific cellulase enzymes of the invention, one or more enzymes which provide detergency, fabric care and/or hygiene benefits.

The above enzymes include cellulase, hemicellulase, peroxidase, protease, glucoamylase, amylase, xylanase, lipase, phospholipase, esterase, cutinase, pectin Enzymes, keratinases, reductases, oxidases, phenoloxidases, lipoxygenases, ligninases, pullulanases, tannases, pentosanases, malanases, beta-glucanases, arabinosidases , hyaluronase, chondroitinase, laccase, or a mixture thereof.

Preferred combinations are laundry detergent compositions containing conventional mixtures of suitable enzymes such as proteases, amylases, lipases, cutinases and/or other cellulases in combination with one or more plant cell wall degrading enzymes. Laundry detergent compositions of the present invention will preferably also contain the ^-43kD endoglucanase derived from Humicola insolens DSM 1800.

Other cellulases useful in the present invention include bacterial or fungal cellulases. They preferably have a pH optimum between 5-12 and an activity in excess of 50 CEVU (Cellulose Viscosity Units). Suitable cellulases are described in US4435307, J61078384 and WO96/02653 by Barbesgoard et al., which disclose cellulase produced by Humicola insolens, Trichoderma, Thielavia and Sporotrichum, respectively. Fungal cellulase. EP739982 describes cellulases isolated from new Bacillus species. Suitable cellulases are also disclosed in GB-A-2075028, GB-A-2095275, DE-OS-2247832 and WO95/26398.

Examples of such other cellulases are cellulases produced by strains of Humicola insolens (Humicolagrisea var. thermoidea), especially Humicola strain DSM 1800. Another suitable cellulase is a ^-43kD endoglucanase exhibiting cellulase activity obtained from Humicola insolens DSM1800; a preferred endoglucanase component has the amino acid sequence disclosed in PCT patent application WO91/17243 . Particularly suitable cellulases are cellulases having a color care effect. Examples of such cellulases are the cellulases described in EP patent application No. 91202879.2 (Novo) filed on 06.11.1991. Carezyme and Celluzyme (Novo Nordisk A/S) are especially useful. See also WO91/17244 and WO91/21801. Other suitable cellulases for fabric care and/or washing performance are described in WO96/34092, WO96/17994 and WO95/24471.

Such other cellulases are typically incorporated into the detergent composition at levels of 0.0001% to 2% pure enzyme by weight of the detergent composition.

Peroxidases are used in combination with oxygen sources such as percarbonate, perborate, persulfate, hydrogen peroxide, etc. and phenolic substrates as bleach boosting molecules. They are used for "solution bleaching", ie to avoid the transfer of dyes or pigments removed from a substrate during washing operations to other substrates in the wash solution. Peroxidases are known in the art and include, for example, horseradish peroxidase, ligninase, and haloperoxidases, such as chloro- and bromo-peroxidases. Detergent compositions containing peroxidase are e.g. PCT International Applications WO89/099813, WO89/09813 and European Patent Applications EP91202882.6 filed on November 6, 1991 and EP No. 96870013.8 filed on February 20, 1996 public. Also suitable are laccases.

Builders are typically present at levels of 0.1% to 5% by weight of the total composition. Preferred synergists are substituted phenothiazines and phenoxazines, 10-phenothiazinepropionic acid (PPT), 10-ethylphenothiazine-4-carboxylic acid (EPC), 10-phenoxazinepropionic acid (POP) and 10-methylphenoxazine (described in WO94/12621) and substituted syringates (C3-C5 substituted alkyl syringates) and phenols. Sodium percarbonate or sodium perborate are preferred sources of hydrogen peroxide.

The above-mentioned peroxidase is usually added to the detergent composition at a content of 0.0001%-2% pure enzyme by weight of the detergent composition.

Other preferred enzymes that may be included in the present invention include lipases. Suitable lipases for detergent use include microorganisms of the genus Pseudomonas, such as the lipid obtained from Pseudomonas stutzeri ATCC 19.154 as disclosed in GB1372034. enzyme. Suitable lipases include those produced by the microorganism Pseudomonas fluorescens IAM 1057 which show positive immunological cross-reactivity with lipase antibodies. This lipase is available from Amano Pharmaceutical Co. Ltd. (Nagoya, Japan) under the trade name Lipase P "Amano", hereinafter referred to as "Amano-P". Other suitable commercial lipases include Amano-CES from Chromobacter viscosum, such as Chromobacter viscosum var. Lipolyticum NRRLB 3673 from ToyoJozo Co. (Tagata, Japan); lipase from USBiochemical Corp. (US) and Disoynth Co. (Netherlands). ) from Chromobacter viscosum lipase; and lipase from Pseudomonas gladioli. Especially suitable lipases are lipases such as M1 Lipase ^R and Lipomax ^R (Gist-Brocades) and Lipolase ^R and Lipolase Ultra ^R (Novo), which have been found to be very effective when used in combination with the compositions of the invention. Also suitable are the lipolytic enzymes described in EP258068, WO92/05249 and WO95/22615 to Novo Nordisk and WO94/03578, WO95/35381 and WO96/00292 to Unilever.

Also suitable are cutinases [EC 3.1.1.50], which are considered a special class of lipases, i.e. lipases that do not require interfacial activation. The incorporation of cutinases in detergent compositions is described eg in WO-A-88/09367 (Genencor); WO90/09446 (Plant Genetic System) and WO94/14963 and WO94/14964 (Unilever).

Lipase and/or cutinase are typically incorporated into the detergent compositions of the present invention at levels of 0.0001% to 2% pure enzyme by weight of the detergent composition.

Suitable proteases are the subtilisins (subtilisins BPN and BPN') obtained from special strains of Bacillus subtilis and Bacillus licheniformis. A suitable protease is obtained from a strain of Bacillus having maximal activity throughout the pH range of 8-12, developed by Novo Industries A/S (Denmark) and marketed as ESPERASE®, hereinafter referred to as "Novo". The preparation of this and similar enzymes is described in GB1243784 to Novo. Other suitable proteases include ALCALASE(R), DURAZYM(R), and SAVINASE(R) from Novo and MAXATASE(R), MAXACAL(R), PROPERASE(R), and MAXAPEM(R) (Maxacal from Protein Engineering) from Gist-Brocades. Proteolytic enzymes also include modified bacterial serine proteases, such as those described in European Patent Application Serial No. 87303761.8 filed April 28, 1987 (particularly pages 17, 24 and 98), referred to herein as "Protease B " and the protease in EP199404, Venegas, published October 29, 1986, which relates to a modified bacterial serine proteolytic enzyme, which is referred to herein as "Protease A". Suitable is the protease referred to herein as "Protease C", which is a variant of the alkaline serine protease obtained from Bacillus in which arginine is replaced by lysine at position 27 and tyrosine at position 104 Instead of valine, asparagine was replaced by serine at position 123 and threonine was replaced by alanine at position 274. Protease C is described in EP90915958.4 published on May 16, 1991, corresponding to WO91/06637. Genetically modified variants, especially variants of Protease C, are also included in the present invention.

A preferred protease called "Protease D" is a carbonyl hydrolase variant having an amino acid sequence not found in nature, such as WO95/10591 and C. Ghosh et al. Compositions" (US Serial No. 08/322677) by substituting various amino acid residues with different amino acids at positions corresponding to +76 in the above-mentioned carbonyl hydrolases, and preferably in combination with substitutions corresponding to Selected from the numbering according to Bacillus amyloliquefaciens subtilisins +99, +101, +103, +104, +107, +123, +27, +105, +109, +126, +128, +135, +156 , +166, +195, +197, +204, +206, +210, +216, +217, +218, +222, +260, +265 and/or +274 one or more amino acid residues The group is derived from a precursor carbonyl hydrolase.

Also suitable for use in the present invention are the proteases described in EP251446 and WO91/06637, BLAP(R) described in WO91/02792 and their variants described in WO95/23221.

See also the high pH protease from Bacillus sp. NCIMB40338 described in WO 93/18140A to Novo. Enzyme detergents comprising a protease, one or more other enzymes and a reversible protease inhibitor are described in WO 92/03529A to Novo. If desired, proteases with reduced adsorption and increased hydrolysis can be obtained as described in Procter & Gamble, WO95/07791. A recombinant trypsin-like protease suitable for use in the detergents of the present invention is described in WO 94/25583 to Novo. Other suitable proteases are described in EP516200 to Unilever.

Proteolytic enzymes are added to the detergent compositions of the present invention at a level of 0.0001%-2%, preferably 0.001%-0.2%, more preferably 0.005%-0.1% pure enzyme by weight of the composition.

Amylases (alpha and/or beta) may be included to remove carbohydrate based stains. WO 94/02597, Novo Nordisk A/S, published February 3, 1994, describes detergent compositions incorporating mutant amylases. See also WO 95/10603, Novo Nordisk A/S, published April 20, 1995. Other amylases known for use in detergent compositions include alpha- and beta-amylases. Alpha-amylases are known in the art and include those described in US5003257, EP252666, WO91/00353, FR2676456, EP285123, EP525610, EP368341 and GB1296839 (Novo). Other suitable amylases are the stability-enhanced amylases described in WO94/18314, published August 18, 1994, and WO96/05295, published February 22, 1996 by Genencor and as described in WO95/10603. Amylase variants with additional modifications in the intermediate parent obtained from Novo Nordisk A/S. Likewise suitable amylases are described in EP277216, WO95/26397 and WO96/23873 (all by Novo Nordisk).

Examples of commercial alpha-amylase products are Purafect OxAm® from Genencor and Termamyl®, Ban®, Fungamyl® and Duramyl®, all from NovoNordisk A/S Denmark. WO95/26397 describes other suitable amylases: α-amylases characterized in that they are determined by the Phadebas® α-amylase activity test in the temperature range 25°C-55°C and at a pH value of 8-10 It has a specific activity at least 25% higher than that of Termamyl(R). Suitable are variants of the above amylases described in WO 96/23873 (Novo Nordisk). Other amylolytic enzymes with improved properties in terms of activity level and combination of thermostability and higher activity level are described in WO95/35382.

Amylolytic enzymes are added to the detergent compositions of the present invention at levels of 0.0001%-2%, preferably 0.00018%-0.06%, more preferably 0.00024%-0.048% pure enzyme by weight of the composition.

The above-mentioned enzymes may be of any suitable origin, such as plant, animal, bacterial, fungal and yeast origin, and the source may also be mesotropic or extreme conditions (psychrophilic, thermophilic, barophilic, basophilic, acidophilic, halogen, etc.). Pure or impure forms of these enzymes can be used. Currently, it is common practice to modify wild-type enzymes via protein/genetic engineering techniques to optimize their performance efficiency in the detergent compositions of the present invention. For example, variants can be designed to increase the compatibility of the enzyme with commonly encountered components of the composition. In addition, variants can be designed such that the optimal pH, bleach or chelator stability, catalytic activity etc. of the enzyme variant can be tailored to a specific wash application.

Particular attention should be paid to oxidation-sensitive amino acids in the case of bleach stability, and to the surface charge for surfactant compatibility. The isoelectric point of this enzyme can be modified by the substitution of some charged amino acids, for example, increasing the isoelectric point will help to improve the compatibility with anionic surfactants. Enzyme stability can be further enhanced by creating, for example, additional salt bridges and strengthening calcium binding sites to increase chelator stability. Particular attention must be paid to cellulases, since most cellulases have a separate binding domain (CBD). The properties of this enzyme can be altered by modifications in these domains.

The enzyme is added to the detergent composition of the present invention at a level of 0.0001% to 2% pure enzyme by weight of the detergent composition. Enzymes can be added as individual components (pellet, granule, stable liquid etc. containing one enzyme) or as a mixture of two or more enzymes (eg cogranulate).

Other suitable detergent ingredients that can be added are enzyme oxidation scavengers described in unexamined European patent application 92870018.6 filed on January 31, 1992, examples of which are ethoxylated tetraethylene Polyamine.

WO9307263A and WO9307260A to Genencor International, WO8908694A to Novo and US3553139 to McCarty et al., issued January 5, 1971 also describe various enzyme materials and their incorporation into synthetic detergent compositions. Enzymes are further disclosed in US Pat. No. 4,101,457, Place et al., issued July 18, 1978, and US Pat. US Patent 4,261,868, Hora et al., issued April 14, 1981, discloses enzyme materials for use in liquid laundry formulations, and their incorporation into such formulations. Enzymes for use in detergents can be stabilized in a variety of ways. Enzyme stabilization techniques are disclosed and enumerated in US3600319 issued August 17, 1971 by Gedge et al. and EP199405 and EP200586 issued October 29, 1986 by Venegas. Enzyme stabilization systems are also described eg in US3519570. WO9401532A to Novo describes a useful Bacillus sp. AC13 capable of deriving proteases, xylanases and cellulases. Color Care and Fabric Care Effects

Technologies that provide color care effect types may also be included. Examples of these technologies are metal catalysts for color protection which are described in co-pending European patent application 92870181.2. Dye fixatives, polyolefin dispersions for anti-wrinkle and improved water absorption, fragrances and amino-functional polymers for color care treatments and fragrance substantivity are other examples of color care/fabric care technologies and were cited in 1996 Described in unexamined patent application №96870140.9 filed on November 7.

Fabric softening agents can also be incorporated into the laundry detergent compositions of the present invention. These reagents can be of inorganic or organic type. Inorganic softeners are, for example, smectite clays as described in GB-A-1400898 and US5019292. Organic fabric softeners include water-insoluble tertiary amines as described in GB-A1514276 and EP-B0011340, their mixtures with mono-C12-C14 quaternary ammonium salts are disclosed in EP-B-0026527 and EP-B-0026528, and as described in EP-B-0026528 - Dilong chain amides disclosed in B-0242919. Other useful organic components for fabric softening systems include the high molecular weight polyethylene oxide materials disclosed in EP-A-0299575 and 0313146.

The amount of smectite clay typically ranges from 2% to 20%, more preferably 5% to 15% by weight, the material being added as a dry blend component to the remainder of the formulation. Organic fabric softeners, such as water-insoluble tertiary amines or dilong-chain amide substances, are added in an amount of 0.5%-5% by weight, usually 1%-3%, while high-molecular-weight polyethylene oxide substances and water-soluble cationic substances It is added in an amount of 0.1%-2%, usually 0.15%-1.5% by weight. These materials are usually added to the spray-dried portion of the composition, although in some cases they may more conveniently be added as dry blended granules or sprayed as a molten liquid onto the other solid components of the composition. bleach

Other optional detergent ingredients that may be included in the laundry detergent compositions of the present invention include bleaches such as hydrogen peroxide, PB1, PB4 and percarbonates having a particle size of 400-800 microns. These bleach components may include one or more oxygen bleaches and, depending on the bleach chosen, one or more bleach activators. Oxygen bleaching compounds, if present, are typically present at levels from about 1% to about 25%.

The bleach component for use in the present invention may be any bleaching agent useful in detergent compositions including oxygen bleaches and others known in the art. Bleaching agents suitable for use in the present invention can be activated or unactivated bleaching agents.

One type of oxygen bleach that can be used includes percarboxylic acid bleaches and salts thereof. Suitable examples of such bleaches include magnesium monoperoxyphthalate hexahydrate, magnesium m-chloroperbenzoate, 4-nonylamino-4-oxoperoxybutyric acid and diperoxydodecane Diacid. Such bleaches are disclosed in US4483781, US Patent Application 740446, EP0133354 and US4412934. Highly preferred bleaching agents also include 6-nonylamino-6-oxoperoxycaproic acid described in US4634551.

Another class of bleaches that can be used includes halogen bleaches. Examples of hypohalite bleaches include, for example, sodium and potassium trichloroisocyanates and dichloroisocyanates and N-chloro and N-bromoalkane sulfonamides. This substance is generally added at 0.5-10% by weight of the final product, preferably 1-5% by weight.

其中R₁是C₇-C₁₃直链或支链饱和或不饱和烷基，R₂是C₁-C₈直链或支链饱和或不饱和烷基和R₃是C₁-C₄直链或支链饱和或不饱和烷基。Hydrogen peroxide releasing agents can be combined with bleach activators such as tetraacetylethylenediamine (TAED), nonanoyloxybenzenesulfonate (NOBS, described in US4412934), 3,5,-trimethylhexanoyloxy phenylsulfonate (ISONOBS, described in EP120591) or pentaacetylglucose (PAG) or N-nonanoyl-6-aminocaproic acid phenolsulfonate (NACA-OBS, described in WO94/28106) in combination , which are perhydrolyzed to form peracids as active bleaching substances, resulting in an improved bleaching effect. Also suitable are the acylated citrate esters disclosed in unexamined EP application 91870207.7 and in unexamined patent applications US No. 60/022786 (filed 30 July 1996) and No. 60/028122 ( Unsymmetrical acyclic imide bleach activators of the formula disclosed in the October 15, 1996 application):

Wherein R ₁ is C ₇ -C ₁₃ linear or branched saturated or unsaturated alkyl, R ₂ is C ₁ -C ₈ linear or branched saturated or unsaturated alkyl and R ₃ is C ₁ -C ₄ straight Chain or branched saturated or unsaturated alkyl.

Useful bleaching agents for use in the detergent compositions of the present invention, including peroxyacids and bleaching systems containing bleach activators and peroxygen bleaching compounds, are described in our co-pending applications USSN08/136626, PCT/US95/07823, Described in WO95/27772, WO95/27773, WO95/27774 and WO95/27775.

Hydrogen peroxide can also be present by adding an enzymatic system (ie enzymes and their substrates) capable of generating hydrogen peroxide at the beginning of the wash or during the wash and/or rinse. This enzyme system is disclosed in EP patent application 91202655.6 filed on October 9, 1991.

Metal-containing catalysts for use in bleach compositions include cobalt-containing catalysts such as cobalt(III) pentaamine acetate and manganese-containing catalysts such as the compounds described in EPA549271, EPA549272, EPA458397, US5246621, EPA458398, US5194416 and US5114611. Bleaching compositions containing peroxygen compounds, manganese-containing bleach catalysts and chelating agents are described in patent application No. 94870206.3. Transition metal complexes of polycyclic rigid ligands are preferred metal-containing catalysts for use in the present invention, as described in unexamined patent applications US No. 60/040629 filed March 7, 1997 by Procter &Gamble; No. 60/039915 ; No. 60/040 222; No. 60/040156; No. 60/040115; No. 60/038714 and No. 60/039920 described.

Bleaching agents other than oxygen bleaching agents are also known in the art and can be used in the present invention. One type of non-oxygen bleaching agent of particular interest includes photoactivated bleaching agents such as sulfonated zinc and/or aluminum phthalocyanines. These materials can be deposited on the soil carrier during the washing process. Upon exposure to light and in the presence of oxygen to dry, for example by hanging the clothes in the sun, the sulfonated zinc phthalocyanine is activated and the soil carrier is subsequently bleached. A preferred zinc phthalocyanine and photoactivated bleaching process is described in US4033718. Detergent compositions will generally contain from about 0.025% to 1.25% by weight of sulfonated zinc phthalocyanine. Builder system

The compositions of the present invention may also contain a builder system. Any conventional builder system is suitable for use herein including aluminosilicate materials, silicates, polycarboxylates, alkyl or alkenyl succinic and fatty acids, materials such as ethylenediaminetetraacetate, Diethylenetriaminepentamethylene acetate, metal ion sequestrants such as aminopolyphosphonates, especially ethylenediaminetetramethylenephosphonic acid and diethylenetriaminepentamethylenephosphonic acid . Phosphate builders are also useful herein.

Suitable builders may be inorganic ion exchange materials, usually inorganic hydrated aluminosilicate materials, more especially hydrated synthetic zeolites such as hydrated zeolite A, X, B, HS or MAP.

Other suitable inorganic builder materials are layered silicates, eg SKS-6 (Hoechst). SKS-6 is a crystalline layered silicate composed of sodium silicate (Na ₂ Si ₂ O ₅ ).

Suitable polycarboxylates containing one carboxyl group include lactic acid, glycolic acid and their ether derivatives disclosed in Belgian Patents 831368, 821369 and 821370. Polycarboxylates containing two carboxy groups include water-soluble salts of succinic acid, malonic acid, (ethylenedioxy) diacetic acid, maleic acid, diglycolic acid, tartaric acid, tartronic acid, and fumaric acid and ether carboxylates described in DE2446686 and 2446687 and US3935257 and thionyl carboxylates described in Belgian patent 840623. Polycarboxylates containing three carboxyl groups include especially water-soluble citrate, aconitate and citraconic acid salts and succinate derivatives, such as carboxymethoxysuccinate described in GB1379241, application in the Netherlands Lactoxysuccinates described in 7205873 and oxypolycarboxylate materials described in GB1387447, eg 2-oxa-1,1,3-propanetricarboxylate.

Polycarboxylates containing four carboxyl groups include oxydisuccinates, 1,1,2,2-ethane tetracarboxylates, 1,1,3,3-propane tetracarboxylates disclosed in GB1261829 and 1,1,2,3-propane tetracarboxylate. Polycarboxylates containing sulfo substituents include sulfosuccinate derivatives disclosed in GB1398421 and 1398422 and US3936448 and sulfonated pyrolytic citrates described in GB1082179, while polycarboxylates containing phosphono substituents Salts are disclosed in GB1439000.

Alicyclic and heterocyclic polycarboxylates include cyclopentane-cis, cis, cis-tetracarboxylate, cyclopentadienide pentacarboxylate, 2,3,4,5-tetrahydrofuran-cis, cis , cis-tetracarboxylate, 2,5-tetrahydrofuran-cis-dicarboxylate, 2,2,5,5-tetrahydrofuran tetracarboxylate, 1,2,3,4,5,6-hexane six Carboxylate salts and carboxymethyl derivatives of polyhydric alcohols such as sorbitol, mannitol and xylitol. Aromatic polycarboxylates include mellitic acid, pyromellitic acid and phthalic acid derivatives disclosed in GB1425343.

Of these, the preferred polycarboxylates are hydroxycarboxylates containing up to three carboxy groups per molecule, more particularly citrates.

Preferred builder systems for use in the compositions of the present invention include water-insoluble aluminosilicate builders, such as zeolite A or layered silicate (SKS-6), and water-soluble carboxylate chelating agents, such as citric acid. mixture.

Other preferred builder systems include mixtures of water-insoluble aluminosilicate builders, such as zeolite A, and water-soluble carboxylate chelating agents, such as citric acid. Preferred builder systems for use in the liquid detergent compositions of the present invention include soaps and polycarboxylates.

Other builder materials which may form part of the builder system for granular compositions include inorganic materials such as alkali metal carbonates, bicarbonates, silicates and organic materials such as organic phosphonates, aminopolyethylene Alkylphosphonates and aminopolycarboxylates.

Other suitable water-soluble organic salts are homo- or co-polymeric acids or their salts, wherein the polycarboxylic acid contains at least two carboxyl groups separated from each other by not more than two carbon atoms. Polymers of this type are disclosed in GB-A-1596756. Examples of such salts are polyacrylates of MW 2000-5000 and their copolymers with maleic anhydride, the copolymers having a molecular weight of 20000-70000, especially about 40000.

Detergent builder salts are generally present in amounts of from 5% to 80%, preferably from 10% to 70%, most often from 30% to 60% by weight of the composition. Chelating agent

The laundry detergent compositions of the present invention may also optionally contain one or more iron and/or manganese chelating agents. Such chelating agents may be selected from amino carboxylates, amino phosphonates, polyfunctionally substituted aromatic chelating agents and mixtures thereof, as defined below. While not wishing to be bound by theory, we believe that the effectiveness of these species is due in part to their excellent ability to remove iron and manganese ions from wash liquors by forming soluble chelates.

Amino carboxylates that can be used as optional chelating agents include EDTA, N-hydroxyethyl EDTA, nitrilotriacetate, EDTA , triethylenetetraminehexaacetate, diethylenetriaminepentaacetate, and ethanol diglycine, their alkali metal, ammonium, and substituted ammonium salts, and mixtures thereof.

Amino phosphonates are also suitable for use as chelating agents in the compositions of the invention when at least low levels of total phosphorus are permitted in detergent compositions, and include ethylenediaminetetrakis (methylene phosphonates), as DEQUEST. The amino phosphonates preferably do not contain alkyl or alkenyl groups of more than about 6 carbon atoms.

Polyfunctionally substituted aromatic chelating agents are also suitable for use in the compositions of the present invention. See US3812044, Connor et al., issued May 21,1974. Preferred compounds of this type in the acid form are dihydroxydisulfobenzenes, such as 1,2-dihydroxy-3,5-disulfobenzene.

The preferred biodegradable chelating agent for use in the present invention is ethylenediamine disuccinate ("EDDS"), particularly the [S, S] isomer, as described in Hartman and Perkins, November 3, 1987. Disclosed in US4704233.

The compositions of the present invention may also contain water-soluble methylglycine diacetic acid (MGDA) salts ( or acid form).

If utilized, these chelating agents will generally comprise from about 0.1% to about 15% by weight of the detergent compositions herein. Even more preferably, if used, these chelating agents comprise from about 0.1% to about 3.0% by weight of the composition. Foam suppressor

Another optional ingredient is a suds suppressor such as silicones and silica-polysiloxane mixtures. Silicones can generally be denoted as alkylated polysiloxane species, while silicas are generally used in finely divided form, eg various types of silica aerosols, xerogels and hydrophobic silicas. These materials can be incorporated as particulates wherein the suds suppressor is advantageously releasably incorporated in a water-soluble or water-dispersible, non-surfactant detergent substantially impermeable carrier. Additionally, the suds suppressor can be dissolved or dispersed in the liquid carrier and added by spraying onto one or more of the other ingredients.

Preferred silicone suds control agents are disclosed in US 3,933,672 to Bartollota et al. Other particularly suitable suds suppressors are the self-emulsifying silicone suds suppressors described in German Patent Application DTOS 2646126, published April 28,1977. An example of such a compound is DC-544, commercially available from Dow Corning, which is a polysiloxane-diol copolymer. Especially preferred suds control agents are suds suppressor systems comprising a mixture of silicone oils and 2-alkyl alkanols. A suitable 2-alkyl-alkanol is 2-butyloctanol, which is commercially available under the tradename Isofol 12R.

This suds suppressor system is described in unexamined European patent application 9287 0174.7, filed November 10, 1992.

Particularly preferred silicone suds control agents are described in unexamined European patent application 92201649.8, said compositions may contain a silicone/silica mixture in combination with a fumed non-porous silica such as Aerosil ^R .

The aforementioned suds suppressors are generally used at a level of 0.001% to 2% by weight of the composition, preferably 0.01% to 1% by weight. other

Other components used in laundry detergent compositions, such as soil suspending agents, soil release agents, optical brighteners, abrasives, bactericides, tarnish inhibitors, colorants and/or encapsulated or unencapsulated spices.

Particularly suitable encapsulating materials are water soluble capsules, as described in GB1464616, which consist of a matrix of polysaccharides and polyols.

Other suitable water-soluble encapsulating materials include dextrins derived from ungelatinized starch esters of substituted dicarboxylic acids as described in US3455838. These ester dextrins are preferably prepared from starches such as soft corn, soft sorghum, sago, tapioca and potato. Suitable examples of such encapsulating materials include N-Lok manufactured by National Starch. N-Lok encapsulating material consists of modified corn starch and dextrose. Starches are modified by adding monofunctional substituent groups such as octenyl succinic anhydride.

Suitable antiredeposition and soil suspension agents herein include cellulose derivatives such as methylcellulose, carboxymethylcellulose and hydroxyethylcellulose and homo- or copolymers of polycarboxylic acids or salts thereof. Polymers of this type include the previously mentioned polyacrylates and maleic anhydride-acrylic acid copolymers as builders, and copolymers of maleic anhydride with ethylene, methyl vinyl ether or methacrylic acid, maleic anhydride The anhydride comprises at least 20 mole percent of the copolymer. These materials are generally used in amounts of 0.5% to 10% by weight, more preferably 0.75% to 8%, most preferably 1% to 6% by weight of the composition.

Preferred optical brighteners are anionic in character, an example of which is 4,4'-bis-(2-ethanolamino-4-anilino-s-triazin-6-ylamino)stilbene-2:2'disulfo Disodium disulfonate, 4,4'-bis-(2-morpholino-4-anilino-s-triazin-6-ylamino)stilbene-2: Disodium 2'disulfonate, 4,4'- Bis-(2,4-dianilino-s-triazin-6-ylamino)stilbene-2: disodium 2'disulfonate, 4',4"-bis-(2,4-dianilino- s-triazin-6-ylamino)stilbene-2-sulfonic acid monosodium, 4,4'-bis-(2-anilino-4-(N-methyl-N-2-hydroxyethylamino)- s-triazin-6-ylamino)stilbene-2: disodium 2'disulfonate, 4,4'-bis-(4-phenyl-2,1,3-triazol-2-yl)stilbene- 2: Disodium 2'disulfonate, 4,4'-bis-(2-anilino-4-(1-methyl-2-hydroxyethylamino)-s-triazin-6-ylamino)stilbene -2: Disodium 2'disulfonate, 2-(stilbene-4"-(naphtho-1',2':4,5)-1,2,3-triazole-2"-sodium sulfonate and 4,4'-bis(2-sulfostyryl)biphenyl. Highly preferred brighteners are the specific brighteners of co-pending European Patent Application 95201943.8.

Other useful polymers are polyethylene glycols, especially polymers having a molecular weight of 1000-10000, more preferably 2000-8000, most preferably about 4000. They are used in amounts of 0.20% to 5%, more preferably 0.25% to 2.5% by weight. These polymers and the homo- or co-polymeric polycarboxylates mentioned above are valuable in improving whiteness retention, fabric dust deposition and wash performance on soil, protein and oxidizable soils in the presence of transition metal impurities of.

Soil release agents useful in the compositions of the present invention are conventional copolymers or terpolymers of terephthalic acid with different arrangements of ethylene glycol and/or propylene glycol units. Such polymers are described in commonly assigned US4116885 and 4711730 and European Patent Application Publication EP0272033, according to EP-A-0272033 especially preferred polymers have the following formula:

(CH ₃ (PEG) ₄₃ ) _0.75 (POH) _0.25 [T-PO) _2.8 (T-

PEG) _0.4 ]T(POH) _0.25 ((PEG) ₄₃ CH ₃ ) _0.75 where PEG is -(OC ₂ H ₄ )O-, PO is (OC ₃ H ₆ O) and T is (pcOC ₆ H ₄ CO) .

Also very useful are modified polyesters such as random copolymers of dimethyl terephthalate, dimethyl sulfoisophthalate, ethylene glycol, and 1-2 propanediol, the end groups mainly consisting of sulfobenzyl Esters and minors consist of monoesters of ethylene glycol and/or propylene glycol. The aim is to have polymers terminated at both ends by sulfobenzoate groups, and in the present invention most of the above-mentioned copolymers according to the invention are "predominantly" terminated by sulfobenzoate groups. However, some copolymers will not be fully end-capped, thus, their end groups may consist of ethylene glycol and/or propylene 1-2 glycol which "secondarily" makes up the material.

The polyester selected for the present invention contains about 46% by weight dimethyl terephthalate, about 16% by weight propane-1,2 glycol, about 10% by weight ethylene glycol, about 13% by weight % dimethyl sulfobenzoate and about 15% by weight sulfoisophthalic acid having a molecular weight of about 3000. Polyesters and their preparation are described in detail in EPA311342.

Free chlorine present in tap water is known to rapidly deactivate enzymes present in detergent compositions. Therefore, the use of chlorine scavengers such as perborate, ammonium sulfate, sodium sulfite or polyethyleneimine in the formulation at levels above 0.1% by weight of the total composition will provide improved stabilization of the detergent enzymes during the wash process. sex. Compositions containing chlorine scavengers are described in European Patent Application 92870018.6 filed 31 January 1992.

Alkoxylated polycarboxylates, such as those prepared from polyacrylates, are useful herein to provide additional grease removal performance. This material is described on pages 4 et seq. of WO91/08281 and PCT90/01815, incorporated herein by reference. Chemically these materials contain polyacrylates with one ethoxy side chain per 7-8 acrylate units. The side chain has the formula -(CH ₂ CH ₂ O) _m (CH ₂ ) _n CH ₃ , where m is 2-3 and n is 6-12. Side chain esters are attached to the polyacrylate "backbone" to provide a "comb" polymer type structure. Molecular weights can vary, but typically range from about 2,000 to about 50,000. The alkoxylated polycarboxylates can comprise from about 0.05% to about 10% by weight of the compositions herein. Dispersant

The laundry detergent compositions of the present invention may also contain dispersants: Suitable water-soluble organic salts are homo- or co-polymeric acids or salts thereof wherein the polycarboxylic acid contains at least two carboxyl groups separated by not more than two carbon atoms.

Polymers of this type are disclosed in GB-A-1596756. Examples of such salts are polyacrylates of MW 2000-5000 and their copolymers with maleic anhydride, the copolymers having a molecular weight of 1000-100000.

In particular, copolymers of acrylate and methacrylate, such as 480N having a molecular weight of 4000, may be incorporated into the laundry detergent compositions of the present invention at levels of from 0.5% to 20% by weight of the composition.

The compositions of the present invention may contain a lime soap peptizer compound having a lime soap dispersing power (LSDP) of not more than 8, preferably not more than 7, most preferably not more than 6, as defined below. Lime soap peptizers are preferably present in an amount of 0% to 20% by weight.

Various measures of the peptizing effect of lime soaps are given by lime soap dispersant power (LSDP), which is obtained by using the paper H.C. Borghetty and C.A. Bergman, J.Am.Oil.Chem.Soc. Determination of the calcium soap dispersion test described on page . This calcium soap dispersion test method is widely used by practitioners in the field and is relevant for example to the following review articles; W.N. Linfield, Surfactant science Series, Vol. 7, p. 3; W.N. Linfield, Tenside surf. det. Vol. 27, pp. 159-163 (1990) and M.K. Nagarajan, W.F. Masler, Cosmetics and Toiletries, Vol. 104, pp. 71-73 (1989). LSDP is the % weight ratio of dispersant to sodium oleate required to disperse calcium soap deposits formed by 0.025 g sodium oleate in 30 ml water of 333 ppm calcium carbonate (calcium: magnesium = 3: 2) equivalent hardness.

Surfactants with good lime soap peptizing capabilities include certain amine oxides, betaines, sultaines, alkyl ethoxy sulfates and ethoxylated alcohols.

Examples of surfactants useful in the present invention having an LSDP of not more than 8 include C ₁₆ -C ₁₈ dimethyl amine oxide, C ₁₂ -C ₁₈ alkyl ethoxysulfates having an average degree of ethoxylation of 1-5 Salts, especially C ₁₂ -C ₁₅ alkyl ethoxysulfate surfactants with an average degree of ethoxylation of 3 (LSDP=4) and surfactants with an average degree of ethoxylation of 12 (LSDP=6) or 30 C ₁₄ -C ₁₅ ethoxylated alcohols sold under the trade names Lutensol A012 and Lutensol A030, respectively, by BASF GmbH.

Polymeric calcium soap peptizers suitable for use in the present invention are described in the article by M.K. Nagarajan, W.F. Masler in Cosmetics and Toiletries, Vol. 104, pp. 71-73 (1989).

Hydrophobic bleaches such as 4-[N-octanoyl-6-aminocaproyl]benzenesulfonate, 4-[N-nonanoyl-6-aminocaproyl]benzenesulfonate, 4-[N-decanoyl- 6-aminocaproyl]benzenesulfonate and mixtures thereof and nonanoyloxybenzenesulfonate are also useful as lime soap peptizing compounds with hydrophilic/hydrophobic bleach formulations. dye transfer inhibition

The laundry detergent compositions of the present invention also comprise compounds which inhibit the transfer of dissolved and suspended dyes from one fabric to another encountered in fabric laundering operations involving colored fabrics. polymeric dye transfer inhibitor

The laundry detergent compositions of the present invention also contain from 0.001% to 10%, preferably from 0.01% to 2%, more preferably from 0.05% to 1% by weight of polymeric dye transfer inhibiting agents. The polymeric dye transfer inhibiting agents are incorporated into laundry detergent compositions to inhibit the transfer of dyes from colored fabrics to fabrics washed therewith. The polymer has the ability to complex or absorb the fugitive dye washed out of the dyed fabric before it has the opportunity to come into contact with other items during the laundering process.

Particularly suitable polymeric dye transfer inhibiting agents are polyamine N-oxide polymers, copolymers of N-vinylpyrrolidone and N-vinylimidazole, polyvinylpyrrolidone polymers, polyvinyloxazolidone and polyvinyl imidazoles or their mixtures.

The addition of this polymer also improves the performance of the enzymes of the invention. a) Polyamine N-oxide polymers

-O-，-S-，-N-；x是0或1；x是0或1；R是脂族、乙氧基化脂族、芳香族、杂环或脂环基团或其任何组合，N-O基团的氮可与其相连或其中N-O基团的氮是这些基团的一部分。Suitable polyamine N-oxide polymers contain units of the formula: Wherein P is a polymerizable unit to which the RNO group may be attached or wherein the RNO group forms part of the polymerizable unit or a combination of both. A is

-O-, -S-, -N-; x is 0 or 1; x is 0 or 1; R is an aliphatic, ethoxylated aliphatic, aromatic, heterocyclic or alicyclic group or any combination thereof , the nitrogen of the NO group may be attached to or wherein the nitrogen of the NO group is part of these groups.

其中R1、R2和R3是脂族基团、芳香族、杂环或脂环基团或它们的组合，x或/和y或/和z是0或1，其中N-O基团的氮可与其连接或其中N-O基团的氮构成这些基团的部分。The NO group can be represented by the following general structure:

wherein R1, R2 and R3 are aliphatic groups, aromatic, heterocyclic or alicyclic groups or combinations thereof, x or/and y or/and z are 0 or 1, wherein the nitrogen of the NO group can be attached to it or wherein the nitrogen of the NO group forms part of these groups.

The N-O groups may be part of the polymerizable unit (P) or may be attached to the polymeric backbone or a combination of both.

Suitable polyamine N-oxides wherein the N-O group forms part of the polymerisable unit include polyamine N-oxides wherein R is selected from aliphatic, aromatic, alicyclic or heterocyclic groups.

One class of the aforementioned polyamine N-oxides includes a group of polyamine N-oxides in which the nitrogen of the N-O group forms part of the R-group. Preferred polyamine N-oxides are those wherein R is a heterocyclic group such as pyridine, pyrrole, imidazole, pyrrolidine, piperidine, quinoline, acridine and derivatives thereof.

Another class of the aforementioned polyamine N-oxides includes a group of polyamine N-oxides in which the nitrogen of the N-O group is attached to the R group.

Other suitable polyamine N-oxides are polyamine oxides in which the N—O groups are attached to the polymerisable units.

A preferred class of these polyamine N-oxides are polyamine N-oxides having the general formula (I), wherein R is an aromatic, heterocyclic or alicyclic group, wherein the nitrogen of the N-O functional group is the R group part.

Examples of such compounds are polyamine oxides wherein R is a heterocyclic compound such as pyridine, pyrrole, imidazole and their derivatives.

Another preferred class of polyamine N-oxides are polyamine oxides of general formula (I), wherein R is an aromatic, heterocyclic or alicyclic group, wherein the nitrogen of the N-O functional group is attached to said R group .

Examples of such compounds are polyamine oxides, where the R group may be aromatic, eg phenyl.

Any polymer backbone can be used so long as the amine oxide polymer formed is water soluble and has dye transfer inhibiting properties. Examples of suitable polymeric backbones are polyethylenes, polyalkylenes, polyesters, polyethers, polyamides, polyimides, polyacrylates and mixtures thereof.

Typically the amine N-oxide polymers of the present invention have a ratio of amine to amine N-oxide of 10:1 to 1:1,000,000. However, the amount of amine oxide groups present in the polyamine oxide polymer can be varied by suitable copolymerization or by suitable degree of N-oxidation. The ratio of amine to amine N-oxide is preferably from 2:3 to 1:1000000, more preferably from 1:4 to 1:1000000, most preferably from 1:7 to 1:1000000. The polymers of the present invention actually include random or block copolymers in which one monomer type is an amine N-oxide and the other monomer type is an amine N-oxide or not. The amine oxide units of the polyamine N-oxides have a PKa<10, preferably a PKa<7, more preferably a PKa<6.

The polyamine oxides can be obtained in almost any degree of polymerization which is not critical provided the material has the desired water solubility and dye-suspending power.

The average molecular weight is usually 500-1,000,000; preferably 1,000-50,000, more preferably 2,000-30,000, most preferably 3,000-20,000. b) Copolymers of N-vinylpyrrolidone and N-vinylimidazole

The N-vinylimidazole N-vinylpyrrolidone polymer used in the present invention has an average molecular weight of 5,000-1,000,000, preferably 5,000-200,000.

Highly preferred polymers for use in the detergent compositions of the present invention include polymers selected from N-vinylimidazole N-vinylpyrrolidone copolymers, wherein said polymer has a An average molecular weight of 10,000-20,000 is most preferred.

The average molecular weight range is determined by light scattering as described in Barth H.G. and Mays J.W. Chemical Analysis, Vol. 113, "Modern Methods for the Characterization of Polymers".

Highly preferred N-vinylimidazole N-vinylpyrrolidone copolymers have an average molecular weight of 5,000-50,000; more preferably 8,000-30,000; most preferably 10,000-20,000.

The N-vinylimidazole N-vinylpyrrolidone copolymers characterized by the above average molecular weights provide excellent dye transfer inhibiting properties without adversely affecting the cleaning performance of detergent compositions formulated therewith.

The N-vinylimidazole N-vinylpyrrolidone copolymer of the present invention has a molar ratio of N-vinylimidazole to N-vinylpyrrolidone of 1-0.2, more preferably 0.8-0.3, most preferably 0.6-0.4. c) Polyvinylpyrrolidone

The detergent composition of the present invention can also use polyvinylpyrrolidone ("PVP") having an average molecular weight of from about 2,500 to about 400,000, preferably from about 5,000 to about 200,000, more preferably from about 5,000 to about 50,000, most preferably from about 5,000 to about 15,000. ). Suitable polyvinylpyrrolidones are commercially available from ISP Corporation, New York, NY and Montreal, Canada under the product names PVP K-15 (viscosity molecular weight 10000), PVP K-30 (average molecular weight 40000), PVP K-60 (average Molecular weight 160000) and PVP K-90 (average molecular weight 360000). Other suitable polyvinylpyrrolidones commercially available from BASF Cooperation include Sokalan HP 165 and Sokalan HP 12; polyvinylpyrrolidones known to those skilled in the detergent field (see e.g. EP-A-262897 and EP-A -256696). d) Polyvinyloxazolidinone:

The detergent compositions of the present invention can also use polyvinyl oxazolidinones having a molecular weight of from about 2,500 to about 400,000, preferably from about 5,000 to about 200,000, more preferably about Average molecular weight from 5,000 to about 50,000, most preferably from about 5,000 to about 15,000. e) Polyvinylimidazole:

The detergent compositions of the present invention may also employ polyvinylimidazole having a value of from about 2,500 to about 400,000, preferably from about 5,000 to about 200,000, more preferably from about 5,000 to about 50,000, and most preferably from about 5,000 to about 50,000, as a polymeric dye transfer inhibiting agent. Average molecular weights from about 5,000 to about 15,000 are preferred. f) Cross-linked polymers:

Cross-linked polymers are polymers in which the backbone is interconnected to some extent; these linkages may be chemical or physical in nature, possibly with reactive groups on the backbone or branches; cross-linked polymers are described in Journal of Polymer Science Described in Vol. 22, pp. 1035-1039.

In one embodiment, the crosslinked polymers are prepared in such a way that they form a three-dimensional rigid structure that is capable of trapping the dye in the pores formed by the three-dimensional structure. In another embodiment, the crosslinked polymer entraps the dye by swelling.

Such crosslinked polymers are described in co-pending patent application 94870213.9. cleaning method

The compositions of the present invention may be used in essentially any washing or cleaning method including soaking methods, pretreatment methods and methods with a rinse step where a separate rinse aid composition may be added.

The method of the present invention involves contacting the fabrics with a wash solution in the usual manner and as described hereinafter.

The method of the invention is generally carried out during a wash. The washing method is preferably carried out at 5°C-95°C, especially at 10°C-60°C, and the pH of the treatment solution is preferably 7-12.

The following examples serve to illustrate the compositions of the present invention without limiting or otherwise defining the scope of the invention.

In detergent compositions, enzyme levels are expressed as pure enzyme by weight of the total composition, and detergent components are expressed by weight of the total composition unless otherwise stated. The abbreviated component symbols have the following meanings: LAS: sodium linear _C11-13 alkylbenzene sulfonate TAS: sodium tallow alkyl sulfate _Cxy AS: _C1x - _C1y sodium alkylsulfate _CxySAS : _C1x -C _1y secondary (2,3) sodium alkyl sulfate C _xy E _z : C _1x -C _1y mainly linear primary alcohols condensed with an average z moles of ethylene oxide C _xy E _z S : with an average z moles Ethylene oxide condensed C _1x -C _1y sodium alkyl sulfate QAS: R ₂ .N ⁺ (CH ₃ ) ₂ (C ₂ H ₄ OH), R ₂ =C ₁₂ -C ₁₄ QAS1 : R ₂ .N ⁺ (CH ₃ ) ₂ (C ₂ H ₄ OH), R ₂ =C ₈ -C ₁₁ APA: C _8-10 Amidopropyldimethylamine Soap: Obtained from 80/20 mixture of tallow and coconut oil fatty acids straight chain alkanes

Sodium carboxylate Neodol 45-13: _C14 - _C15 linear primary alcohol ethoxylate, sold by Shell Chemical CO APG: C8-16 fatty alcohol group attached to a hydrophilic part consisting of glucose units

Group of alkyl polyglucosides, the degree of polymerization is 1.1-3STS: sodium toluenesulfonate CFAA: C ₁₂ -C ₁₄ alkyl N-methylglucamide TFAA: C ₁₆ -C ₁₈ alkyl N-methylglucose Amide TPKFA: C ₁₂ -C ₁₄ topped whole fraction fatty acid DEQA: Di-(tallow-oxy-ethyl)dimethylammonium chloride DEQA(2): Di-(soft-tallow-oxyethyl Base) Hydroxyethyl methyl ammonium methyl sulfate DTDMAMS: ditallow dimethyl ammonium methyl sulfate SDASA: ratio 1:2 stearyl dimethylamine: triple pressure stearic acid silicate: amorphous Sodium silicate (SiO ₂ :Na ₂ O ratio = 1.6-3.2) Zeolite A: hydrated sodium aluminosilicate of formula Na ₁₂ (AlO ₂ SiO ₂ ) ₁₂ .27H ₂ O, primary particle size

0.1-10 microns (weight expressed on anhydrous basis ₎ NaSKS-6: crystalline layered silicate of formula δ- _Na2Si2O5 Citrate: _trisodium citrate dihydrate, active 86.4%, Particle Size Distribution 425-

850 micron citric acid : anhydrous citrate borate : sodium borate carbonate : anhydrous sodium carbonate, particle size 200-900 micron bicarbonate : anhydrous sodium bicarbonate, particle size distribution 400-1200 micron sulfuric acid Salt : Anhydrous Sodium Sulfate Magnesium Sulfate : Anhydrous Magnesium Sulfate STPP : Sodium Tripolyphosphate TSPP : Tetrasodium Pyrophosphate MA/AA : 4:1 Acrylate/Maleate Random Copolymer, Average Molecular Weight Approx.

70000-80000MA/AA1: 6:4 acrylate/maleate random copolymer, average molecular weight about 10000AA: sodium polyacrylate polymer with average molecular weight 4500 PB1: anhydrous sodium perborate monohydrate, nominal formula : NaBO ₂ .H ₂ O ₂ PB4 : Sodium perborate tetrahydrate, nominal formula: NaBO ₂ .3H ₂ OH ₂ O ₂ percarbonate : Anhydrous sodium percarbonate, nominal formula: 2Na ₂ CO ₃ . _3H2O2NaDCC : Sodium Dichloroisocyanurate TAED: Tetraacetylethylenediamine NOBS: Nonanoyloxybenzenesulfonate, sodium salt form NACA-OBS: (6 _- Nonanoylaminocaproyl)oxybenzene Sulfonate DTPA: Diethylenetriaminepentaacetic acid HEDP: 1,1-hydroxyethanediphosphonic acid DETPMP: Diethyltriaminepenta(methylene)phosphonate, sold by Monsanto under the trade name

Dequest 2060 sells EDDS : Ethylenediamine-N,N'-disuccinic acid, (S,S) isomer, sodium salt form Photoactivated Bleach : Sulfonated Zinc Phthalate Encapsulated with Dextrin-Soluble Polymer Cyanine Photoactivated Bleach 1: Sulfonated Aluminum Phthalocyanine Protease Encapsulated with Dextrin-Soluble Polymer: Trade Names Savinase, Alcalase, Durazym (Novo Nordisk

A/S), Maxacal, Maxapem (Gist-Brocades) sold protein fractions

Lyase and in patents WO91/06637 and/or WO95/10591 and/or

Protease amylase described in EP251446: sold by Genencor described in WO94/18314, WO96/05295

Amylolytic enzymes from Purafact Ox Am®; Termamyl®, Fungamyl®

and Duramyl®, both obtained from Novo Nordisk A/S and in

Amylase lipase described in WO95/26397 : sold under the trade names Lipolase, Lipolase Ultra by Novo Nordisk A/S

and the lipolytic enzyme marketed as Lipomax by Gist-Brocades Cellulase: a cellulolytic enzyme marketed as Endolase by Novo Nordisk A/S Other Cellulase: a cellulase marketed under the trade name Carezyme by Novo Nordisk A/S Enzyme CMC : Sodium carboxymethyl cellulose PVP : Polyvinyl polymer with an average molecular weight of 60,000. PVNO : Polyvinylpyridine-N-oxide, with an average molecular weight of 50,000. PVPVI : Copolymer of vinylimidazole and vinylpyrrolidone, with an average molecular weight of 20,000 Brightener 1 : 4,4'-bis(2-sulfostyrene)biphenyl disodium Brightener 2 : 4,4'- Bis(4-anilino-6-morpholino-1,3,5-triazin-2-yl)stilbene-

2: 2'-disodium disulfonate polysiloxane disinfectant: polydimethylsiloxane foam agent containing siloxane-oxyalkylene copolymer as a dispersant foam control agent, the foam control agent and the The ratio of dispersant is

10:1-100:1. Foam suppressor: 12% polysiloxane/silicon dioxide, 18% stearyl alcohol, 70% starch, granules

Form Sunscreen: Water-based monostyrene latex blend by BASF Aktiengesellschaft

_Marketed under the trade name Lytron 621 SRP1: anion-terminated polyester SRP2: diethoxylated poly(1,2-propylene terephthalate) short block polymer QEA: bis(( _C2H5O ) (C ₂ H ₄ O) _n )(CH ₃ )-N ⁺ -C ₆ H ₁₂ -N ⁺ -(CH ₃ )bis((C ₂ H ₅ O)-

(C ₂ H ₄ O)) _n , where n=20-30PEI: Polyethyleneimine, average molecular weight 1800, average ethoxylation degree for each

Nitrogen 7 ethyleneoxy residues SCS : Sodium cumene sulfonate HMWPEO : High molecular weight polyethylene oxide PEGx : Polyethylene glycol, molecular weight xPEO : Polyethylene oxide, average molecular weight 5000 TEPAE : Tetraethylene pentamine Ethoxylate Example 1

A high density laundry detergent composition of the present invention was prepared as follows:

II III IV V Vila 8.0 8.0 8.0 2.0 6.0 6.0TAS-0.5-0.5 1.0 0.1C46 (S) AS 2.5------7.0 4.5 5.5C68AS 1.0 6.0---3.4 8.0 3.66 3.6APG 1.0 1.0 1.0 2.0 1.0 1.0C25E7 3.4 3.4 1.0--C25E3S--2.0 5.0 4.5QAS-0.8--qas 1-0.8 0.5 1.0 Burrastone A 18.0 14.1 18.0 18.1 Citric acid---------- 2.5-2.5 carbonate 13.0 13.0 27.0 10.0 10.0 13.0NA-SKS-6--10.0-10.0 silicate 1.4 1.4 3.0 0.5 0.3 Citrate-1.0-3.0-Sulfate 26.1 26.1 6.0--sulfuric acid Magnesium 0.3-0.2-0.2mA/AA 0.3 0.3 0.3 4.0 1.0 1.0cmc 0.2 0.2 0.2 0.4 0.4 9.0 9.0 5.0---18.0 18.0TAed 1.5 0.4 1.5-3.9.2NACA-OBS -2.0 1.0--DetPMP 0.25 0.25 0.25 0.25 -SRP1-0.2 — 0.2edds-0.25 0.4-0.5 0.5CFAA-1.0-2.0 -Hedp 0.3 0.3 0.3 0.4QEA--0.2-0.5 fiberin Enzyme 0.005 0.008 0.01 0.05 0.003 0.0005 protease 0.009 0.009 0.01 0.04 0.05 0.03 amylase 0.002 0.002 0.006 0.008 0.008 Other cellulose enzyme 0.0007-0.0007 0.006-0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.0 (PPM) PVNO/PVPVI--0.1--0.09 0.09 0.09-0.09 0.09 spice 0.3 0.3 0.4 0.4 0.4 polysilicidal foam 0.5 0.5 0.3 0.3 density, G/L 850 850 850 850 850 850 Minor/trace components up to

100% Example 2

Preparation of granular laundry detergent compositions according to the invention for use especially under European washing machine conditions:

I        II       III      IV       V        VIAPG             1.0      1.0      2.0      2.0      2.0      1.5LAS             5.5      7.5      5.0      5.0      6.0      7.0TAS             1.25     1.9      -        0.8      0.4      0.3C24AS/C25AS     -        1.2      3.0      3.0      3.0      2.0C25E3S          -        0.8      1.0      1.5      3.0      1.0C45E7           2.25     -        -        -        -        3.0TFAA -2.0--C25E5-5.5---qas 0.8----qas 1 — 0.7 1.0 0.0 0.7stpp 19.7----19.5 25.0 19.5 20.0na-SKS-6/Lemon Acid-10.6-10.6- (79: 21) NA-SKS-6-9.0-10.0 10.0 carbonate 6.1 21.4 9.0 10.0 10.0 18.0 hydrogen-2.0 7.0-2.0 silicate 6.8-0.3 0.5-- Citic acid-4.0 4.0--sulfate 39.8-5.0-12.0 magnesium sulfate-0.2 0.2 -ma/AA 0.5 1.6 3.0 4.0 1.0cmc 0.2 0.4 1.0 1.0 0.4pb4 5.0 12.7---over-carbon-over carbon passing carbon passing carbon passage Acid Salt 0.5 3.1-5.0 -NACA-OBS 1.0 3.5-2.5Detpmp 0.25 0.3 0.2Hedp-0.3 0.3 0.3QEA-1.0 1.0-cellulose enzyme enzyme 0.00.005 0.006  0.003  0.0003 0.003蛋白酶                0.009   0.03    0.03   0.05   0.05   0.02脂酶                  0.003   0.003   0.006  0.006  0.006  0.004其它纤维素酶          0.0006  0.0006  0.0005 0.0005 0.0007 0.0007淀粉酶                0.002   0.002   0.006  0.006  0.01   0.003PVNO/PVPVI            -       -       0.2    0.2    -      -PVP                   0.9     1.3     - -0.9SRP1-0.2 0.2 0.2-Light activation bleach (PPM) 15 27-20 20 20 light activation bleach 15-- (1) (PPM) white agent 1 0.08 0.2-0.09 0.15 increase white white white white Dose 2-0.04---spice 0.3 0.5 0.4 0.3 0.4 0.3 Polyshiloxane removal agent 0.5 2.4 0.3 0.5 0.3 2.0 density, G/L 750 750 750 750 750 components/trace components up to the most up

100% Example 3

Detergent compositions according to the invention, especially for use in European washing machine washing conditions, are prepared as follows.

I I II II III III IV Blowing Powder

LAS 6.0 5.0 11.0 6.0

TAS 2.0 - - - 2.0

Zeolite A 24.0 - - - 20.0

STPP - - 27.0 - 24.0 -

Sulfates 4.0 6.0 13.0 -

MA/AA 1.0 4.0 6.0 2.0

Silicate 1.0 7.0 3.0 3.0

CMC 1.0 1.0 0.5 0.6

Brightener 1 0.2 0.2 0.2 0.2

      Silicone defoamer 1.0 1.0 1.0 0.3

DETPMP 0.4 0.4 0.2 0.4

APG 1.6 1.5 1.0 1.0 Spray On

                                                                             

C45E7 - - - - - 3.0

C45E2 2.5 2.5 2.0 -

APG 1.0 1.0 1.0 1.0

Spices 0.5 0.3 0.5 0.2

Silicone defoamer 0.3 0.3 0.3 - dry additive

QEA - - - - - 1.0

EDDS 0.3 - - -

Sulfate 2.0 3.0 5.0 10.0

Carbonate 6.0 13.0 15.0 14.0

Citric Acid 2.5 - - - 2.0

                                           

Na-SKS-6 10.0 - - -

                                                                                  

PB4 - 18.0 10.0 21.5

TAED 2.0 2.0 - 2.0

NACA-OBS 3.0 2.0 4.0 -

Cellulase 0.005 0.001 0.006 0.0004

Protease 0.03 0.03 0.03 0.03

Lipase 0.008 0.008 0.008 0.004

Amylase 0.003 0.003 0.003 0.006

Brightener 1 0.05 - - - 0.05

Trace and Minor Components Up to 100% Example 4

The granular detergent compositions of the present invention were prepared as follows:

I Blowing Powder II II III III IV V V VI Blowing Powder

APG 1.0 1.0 2.0 2.0 - -

LAS 23.0 8.0 7.0 9.0 7.0 7.0

TAS - - - - - - 1.0 -

C45AS 5.0 5.0 4.0 6.0 - -

C45AES - 1.0 1.0 1.0 -

C45E35 - - - - - - 2.0 4.0

  Zeolite A 10.0 18.0 14.0 12.0 10.0 10.0

MA/AA - 0.5 - - - - 2.0

MA/AA1 7.0 - - - - - - - -

AA - 3.0 3.0 2.0 3.0 3.0

Sulfate 5.0 6.3 14.3 11.0 15.0 19.3

Silicate 10.0 1.0 1.0 1.0 1.0 1.0

Carbonate 15.0 20.0 10.0 20.7 8.0 6.0

PEG4000 0.4 1.5 1.5 1.0 1.0 1.0

DTPA - 0.9 0.5 - - 0.5

Brightener 2 0.3 0.2 0.3 - 0.1 0.3 Spray liquid

C45E7 - 2.0 - - - 1.0 1.0

C25E9 3.0 - - - - - - -

C23E9 - - - 1.5 2 - 2.0

APG - - - - - - - 1.0 1.0

Fragrance 0.3 0.3 0.3 2.0 0.3 0.3 Agglomerates

C45AS - 5.0 5.0 2.0 - 5.0

LAS - 2.0 2.0 - - - 2.0

Zeolite A - 7.5 7.5 8.0 - 7.5

Carbonate - 4.0 4.0 5.0 - 4.0

PEG4000 - 0.5 0.5 - - - 0.5 Minor components (water, etc.) - 2.0 2.0 2.0 - - 2.0 Dry additive

QAS - - - - - - - 1.0 -

Citric acid - - - - - - - 2.0 -

PB4 - - - - - - - 12.0 1.0

PB1 4.0 1.0 3.0 2.0 - -

Percarbonate - - - - - - 2.0 10.0

Carbonate - 5.3 1.8 - 4.0 4.0

NOBS 4.0 - 6.0 - 0.6

Methylcellulose 0.2 - - - - - - - -

Na-SKS-6 8.0 - - - - - - -

STS - - - 2.0 - 1.0 -

cumenesulfonic acid - 1.0 - - - - 2.0

Cellulase 0.005 0.01 0.0004 0.0005 0.005 0.005

Protease 0.02 0.02 0.02 0.01 0.02 0.02

Lipase 0.004 - 0.004 - 0.004 0.008

Amylase 0.003 - 0.002 - 0.003 -

Other cellulase 0.0005 0.0005 0.0005 0.0007 0.0005 0.0005

PVPVI - - - - - - - 0.5 0.1

PVP - - - - - - - 0.5 -

PVNO - - - 0.5 0.3 -

QEA - - - - - - - 1.0 -

SRP1 0.2 0.5 0.3 - 0.2 -

Silicone defoamer 0.2 0.4 0.2 0.4 0.1 -

Magnesium Sulfate - - - 0.2 - - 0.2 -

Trace and Minor Groups Up to

Points 100% Example 5

A bleach-free detergent composition according to the invention, especially for washing colored clothes, is prepared as follows:

I II II III

Blown Powder

Zeolite A 15.0 15.0 -

Sulphate - 5.0 -

LAS 3.0 3.0 -

DETPMP 0.4 0.5 -

CMC 0.4 0.4 -

MA/AA 4.0 4.0 -

Agglomerates

C45AS - - - - 11.0

LAS 6.0 5.0 -

TAS 3.0 2.0 -

Silicate 4.0 4.0 -

Zeolite A 10.0 15.0 13.0

CMC - - - - 0.5

MA/AA - - - - 2.0

Carbonate 9.0 7.0 7.0

APG 2.0 2.0 2.0

Spray liquid

Spices 0.3 0.3 0.5

C45E7 4.0 4.0 4.0

  Dry Additives

MA/AA - - - - 3.0

NaSKS-6 - - 12.0

Citrate 10.0 - 8.0

Bicarbonate 7.0 3.0 5.0

Carbonate 8.0 5.0 7.0

PVPVI/PVNO 0.5 0.5 0.5

  Cellulase                                                                      

Protease 0.03 0.02 0.05

Lipase 0.008 0.008 0.008

  Amylase                                                                              

  Other cellulase                                                                              

  Silicone Defoamer                                                                                          

Sulfates - - 9.0 -

Density (g/l) 700 700 700

Minor and minor components up to 100% Example 6

The following detergent compositions according to the invention were prepared:

I II II III III IV

Binder particles

Zeolite A 30.0 22.0 24.0 10.0

Sulfate 10.0 5.0 10.0 7.0

MA/AA 3.0 - - -

AA - - 1.6 - 2.0 -

MA/AA1 - 12.0 - 6.0

LAS 14.0 10.0 9.0 20.0

C45AS 8.0 7.0 9.0 7.0

C45AES - 1.0 1.0 -

Silicate - 1.0 0.5 10.0

Soap - - 2.0 -

Whitening agent 1 0.2 0.2 0.2 0.2

Carbonate 6.0 9.0 10.0 10.0

                                                           

DTPA - 0.4 -

Spray liquid

C25E9 - - - - - 4.0

APG 1.0 1.0 1.0 1.0

C23E9 - 1.0 1.5 -

Fragrances 0.2 0.3 0.3 - Dry Additives

Carbonate 5.0 10.0 18.0 8.0

PVPVI/PVNO 0.5 - 0.3 -

    Cellulase     0.0005 0.006 0.0008 0.002

Protease 0.03 0.03 0.03 0.02

Lipase 0.008 - - - 0.008

                                                                               

  Other cellulase 0.0002 0.0005 0.0005 0.0002

NOBS - 4.0 - 4.5

PB1 1.0 5.0 1.5 6.0

Sulfates 4.0 5.0 - 5.0

SRP1 - 0.4 -

                                                                        

Minor components and trace components up to 100% Example 7

The granular detergent compositions of the present invention were prepared as follows:

I II II III III

blown powder

Zeolite A 20.0 - 15.0

                                                          

Sulfates - - - 5.0

Carbonate - - - - 5.0

TAS - - - - 1.0

LAS 6.0 6.0 6.0

C68AS 2.0 2.0 -

Silicate 3.0 8.0 -

MA/AA 4.0 2.0 2.0

CMC 0.6 0.6 0.2

Whitening agent 1 0.2 0.2 0.1

DETPMP 0.4 0.4 0.1

STS - - - - 1.0

Spray liquid

C45E7 4.0 4.0. 3.0

APG 1.0 1.0 1.0

                                                                                         

Spices 0.2 0.2 0.3

DRY ADDITIVES

QEA - - - - 1.0

Carbonate 14.0 9.0 10.0

PB1 1.5 2.0 -

PB4 18.5 13.0 13.0

TAED 2.0 2.0 2.0

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - 1.0

                                                                                               

Na-SKS-6 - - - 3.0

                                                                           

Protease 0.03 0.03 0.007

                                                                                 

                                                                               

  Other cellulase   0.0002 0.0002 0.0005

Sulfate 10.0 20.0 5.0

Density (g/l) 700 700 700

Trace and Minor Components Up to 100% Example 8

The following detergent compositions of the present invention were prepared:

I II II III

blown powder

Zeolite A 15.0 15.0 15.0

Sulfate - 5.0 -

LAS 3.0 3.0 3.0

                                                                                                                                                    

DETPMP 0.4 0.2 0.4

EDDS - 0.4 0.2

CMC 0.4 0.4 0.4

MA/AA 4.0 2.0 2.0 Agglomerates

LAS 5.0 5.0 5.0

TAS 2.0 2.0 1.0

Silicate 3.0 3.0 4.0

Zeolite A 8.0 8.0 8.0

Carbonate 8.0 8.0 4.0

APG 1.1 1.0 1.0 spray liquid

Spices 0.3 0.3 0.3

C45E7 1.0 1.0 1.0

                                              

Citrate 5.0 - 2.0

Bicarbonate - 3.0 -

Carbonate 8.0 15.0 10.0

TAED 6.0 2.0 5.0

PB1 14.0 7.0 10.0

PEO - - - - 0.2

Bentonite - - - - 10.0

                                                                               

Protease 0.03 0.03 0.03

                                                                             

    Other cellulase   0.001   0.001     0.001

                                                                                 

                                                                                           

Sulfates - 30 -

Density (g/l) 850 850 850

Minor and minor components up to 100% Example 9

The following detergent compositions of the present invention were prepared:

I I II II III III IV

LAS 18.0 14.0 24.0 20.0

QAS 0.7 1.0 - 0.7

TFAA - 1.0 -

C23E56.5 - 1.0 - -

C45E7 - 1.0 - -

C45E3S 1.0 2.5 1.0 -

APG 2.0 2.0 2.0 2.0

STPP 30.0 16.0 28.0 20.0

Silicate 9.0 5.0 9.0 8.0

Carbonate 11.0 7.5 10.0 5.0

Bicarbonate - 7.5 - -

PB1 3.0 1.0 - -

PB4 - 1.0 - -

NOBS 2.0 1.0 - -

DETPMP - 1.0 - -

DTPA 0.5 - 0.2 0.3

SRP1 0.3 0.2 - 0.1

MA/AA 1.0 1.5 2.0 0.5

CMC 0.8 0.4 0.4 0.2

PEI - - - - - 0.4 -

Sulphate 20.0 10.0 20.0 30.0

Magnesium Sulfate 0.2 - 0.4 0.9

Cellulase 0.0005 0.008 0.008 0.005

Protease 0.03 0.03 0.02 0.02

Amylase 0.008 0.007 - 0.004

Lipase 0.004 - 0.002 -

Other cellulases 0.0003 - - - 0.0001

Photoactivated Bleach 30ppm 20ppm - 10ppm

Spice 0.3 0.3 0.1 0.2

Brightener 1/2 0.05 0.02 0.08 0.1

Trace and Minor Components Up to 100% Example 10

Prepare the following liquid detergent formulation of the present invention (content is given in parts by weight, and enzyme is expressed with pure enzyme):

II III IV VLAS 11 7.8-3.9 -C25E2.5S-3.0 17.0-15.0C45E2.25S 10.5 3.0-14.7 -C23E9-2.7 1.8 1.0C23E7 3.2--APG 1.0 1.0CFAA-5.2-3.1 TPKFA 1.6-2.0 0.5 2.0 Citric acid (50 %) 6.5 1.2 2.5 4.4 2.5 Calcium Tyanate 0.1 0.06 0.1-0.5 0.06 0.05 0.05SCS 4.0 1.0 1.2-Borate 0.6-3.0 2.9 sodium hydroxide 5.8 2.0 3.5 3.5 3.5 3.5 3.5 3.5 3.5 3.5 3.7 2.7 Ethanol 1.75 1.0 3.6 4.2 2.91, 2 propylene glycol 3.3 2.0 8.0 7.9 5.3 Ethanol 3.0 1.5 1.3 2.5 0.8tepa 1.6-1.3 1.2 1.2 Corteease 0.003 0.0008 0.01 protease 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.03 0.0222 0.0222 0.02 0.02 0.0.0 0.03 0.02 0 0.01 0.01 0.03 0.01 0.03 0.03 0.03 0. 0.03 0.03-. Amylorase--0.002-Other cellulose enzyme-0.0002 0.0005 0.0001SRP1 0.2-0.1 -DTPA-0.3 -PVNO-0.3-0.2 whitening agent 1 0.2 0.07 0.1-polysiloxane foam agent 0.04 0.02 0.1 0.1 0.1 Minor components and water Example 11

Prepare the following liquid detergent formulation of the present invention (content is given in parts by weight, and enzyme is expressed with pure enzyme):

I I II II III III IV

LAS 10.0 13.0 9.0 -

C25AS 4.0 1.0 2.0 10.0

C25E3S 1.0 - 3.0

C25E7 5.0 7.0 11.0 1.5

APG 1.0 2.0 2.0 2.2

TFAA - - - - - - 4.5

APA - 1.4 - -

TPKFA 2.0 - 13.0 7.0

Citric acid 2.0 3.0 1.0 1.5

Dodecenyl/Ten 12.0 10.0 - -

Carbenylsuccinic acid

Rapeseed fatty acid 4.0 2.0 1.0 -

Ethanol 4.0 4.0 7.0 2.0

1,2 Propylene Glycol 4.0 4.0 2.0 7.0

Monoethanolamine - - - - - - 5.0

Triethanolamine - - - - 8.0 -

TEPAE 0.5 - 0.5 0.2

DETPMP 1.0 1.0 0.5 1.0

Cellulase 0.005 0.005 0.01 0.006

Protease 0.02 0.02 0.01 0.008

Lipase - 0.002 - 0.002

Amylase 0.004 0.004 0.01 0.008

Other cellulases - - - - - - 0.002

SRP2 0.3 - 0.3 0.1

Boric acid 0.1 0.2 1.0 2.0

Calcium Chloride - 0.02 - 0.01

Brightener 1 - 0.4 -

Foam suppressant 0.1 0.3 - 0.1

Sunscreen 0.5 0.4 - 0.3

Sodium hydroxide up to 8.0 8.0 7.6 7.7

pH

Minor Components and Water Example 12

Prepare the following liquid detergent composition of the present invention (content is given in parts by weight, and enzyme is expressed with pure enzyme):

I        II        III        IVLAS                         23.0       -         -          -C25AS                       -          11.0      16.0       13.0C25E3S                      -          2.0       2.0        4.0C25E7                       -          -         4.0        4.0APG                         2.0        2.0       2.0        2.0TFAA                        -          6.0       8.0        8.0APA                         3.0        1.0       2.0        -TPKFA                       -          15.0      11.0       11.0柠檬酸                      1.0        1.0       1.0        1.0十Phantarine-based/fourth carbonine-based amber 15.0--cauliflower fatty acid 1.0-3.5-ethanol 7.0 2.0 3.01, 2 propena diol 6.0 8.0 10.0 13.0 single ethanlamine-9.0 TEPAE-0.4 0.3detPMP 2.0 1.0 1.0- Celloinase 0.008 0.005 0.005 0.01 protease 0.08 0.02 0.01 0.02 lipase-0.003 0.003 amylase 0.01 0.01 0.01 Other cellulose enzyme-0.003srp2-0.2 0.1 boric acid 1.5 2.5 2.5 Pensoil 4.0---increase white agent. 1 0.1 0.2 0.3-Foaming agent 0.4---Solite 0.8 0.7--sodium hydroxide up to PH 8.0 7.5 8.0 8.2 trace components and water implementation examples 13

Prepare the following liquid detergent composition of the present invention (content is given in parts by weight, and enzyme is expressed with pure enzyme):

I II

LAS 27.6 17.9

C45AS 11.8 4.9

C13E8 3.0 3.1

APG 1.9 2.0

Oleic acid 3.4 2.5

Citric acid 5.4 5.4

Sodium hydroxide 0.4 3.6

Calcium formate 0.2 0.1

Sodium formate - 0.5

Ethanol 7.0 7.0 -

Monoethanolamine 16.5 8.0

1,2 Propylene Glycol 5.9 5.5

Xylenesulfonic acid - 2.4

TEPAE 1.5 0.8

Protease 0.05 0.02

Cellulase 0.005 0.005

PEG - 0.7

Brightener 2 0.4 0.1

Spices 0.5 0.3

Minor Components and Water Example 14

The following granular fabric detergent compositions according to the present invention are prepared which have the ability to "soften in the wash":

I II

C45AS - 9.5

LAS 7.1 7.1 -

C68AS 1.3 1.3 -

C45E7 3.5 3.5 -

C25E3 - 4.5

APG 1.0 1.0

Coconut Alkyl Dimethyl Hydroxyethyl Chloride 1.4 1.0

ammonium chloride

Citrate 5.0 3.0

Na-SKS-6 - 11.0

Zeolite A 15.0 15.0

MA/AA 4.0 4.0

DETPMP 0.4 0.4

PB1 15.0 15.0 -

Percarbonate - 15.0

TAED 5.0 5.0

Green Soil 10.0 10.0

HMWPEO - 0.1

Cellulase 0.005 0.01

Protease 0.02 0.01

Lipase 0.02 0.01

Amylase 0.03 0.005

Other cellulases 0.001 -

Silicate 3.0 5.0

Carbonate 10.0 10.0

Foam suppressant 1.0 4.0

CMC 0.2 0.1

Trace and Minor Components Up to 100% Example 15

A rinse-in fabric softener composition of the present invention was prepared as follows:

APG 0.5

DEQA(2) 20.0

Cellulase 0.005

Other cellulase 0.001

Hydrochloric acid 0.03

Defoamer 0.01

Blue dye 25ppm

Calcium chloride 0.20

Spices 0.90

Minor components and water up to 100% Example 16

Fabric softener and dryer added fabric conditioner compositions of the present invention were prepared as follows:

II III IV VDEQA 2.6 19.0--DEQA (2)---51.8dtmams--26.0 -SDASA-70.0 40.2IV = 0 stearic acid 0.3----Neodol45-13.0- 13.0- -On 0.02 0.02---ethanol-1.0 -lase spice 1.0 1.0 0.75 1.0 1.5glycoperse S-20--15.4 Glycerin single-to-26.0-Amber dicer ester-0.38-0.38- -Capyroscopic foaming agent 0.01 0.01--electrolyte-0.1--cellulose enzyme 0.005 0.008 0.005 0.002apg 0.5 1.0 0.5 0.5 1.0 clay--3.0-dye 10PPM 0.01-water and a small number of components 100% 100% - - - -Example 17

Prepare the following laundry bar detergent composition of the present invention (content is given in parts by weight, and enzyme is represented by pure enzyme):

II III IV Vii Vi VLAS-17.0 13.0 19.0 6.75 7.8 -C28AS 28.0 11.5-13.75 10.2 20.5 May Cinnamin 2.5 9.0-----APG 2.0 2.0 2.0 2.0 2.0 2.0 1.25- -1.25 1.25 1.25 carbonate 20.0 3.0 13.0 8.0 15.0 15.0 10.0 calcium carbonate 27.5 35.0-40.0-40.0 Sulfate 5.0 5.0 3.0-5.0TSPP 5.0-5.0 -Stpp 5.0 10.0-0.0- -7.0 8.0 10.0 Policy-10.0-5.0--Detpmp-0.7 0.6 0.7 0.7 0.7cmc-1.0 1.0 1.0 1.0-1.0 talc- 10.0 15.0 10.0--4.0 5.0 3.0--------4.0 5.0 3.0-------- 4.0 5.0 3.0-- -PVNO          0.02     0.03   -       0.01    -        0.02    -      -MA/AA         0.4      1.0    -       -       0.2      0.4     0.5    0.4SRP1          0.3      0.3    0.3     0.3     0.3      0.3     0.3    0.3纤维素酶      0.005    .0005  0.005   0.008   0.005    0.007   0.007  0.01淀粉酶        -        -      0.01    -       -        - 0.002-protease-0.004-0.003 0.003-0.003 lipase-0.002-0.002--other cellulose-.0003-.0003 .0002-enzyme PEO-0.2 0.3-0.3 spice 1.0 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.4-0.4 Magnesium sulfate-3.0 3.0 3.0--increase agent 0.15 0.15--0.1 Light activation bleach-15.0 15.0 15.0-15.0 doses (PPM) (PPM)

Claims (13)

1. laundry detergent composition, it contains alkyl poly glucoside surfactant and best pH is 4-10 and the fungal cellulase that does not have cellulose binding domain.

2. according to the laundry detergent composition of claim 1, wherein said cellulase is by Humicola isolens, Trichoderma longibrachiatum, and Trichodermareseei and/or viride (Trichoderma viride) obtain.

3. according to the laundry detergent composition of claim 1-2, the feature of wherein said cellulase also is to show below character: (a) by Humicola insolens, DMS 1800 obtains; (b) the about 50kDa of approximate molecular weight; (c) iso-electric point is about 5.5; (d) contain 415 amino acid.

4. according to the laundry detergent composition of claim 1-2, the feature of wherein said cellulase also is to show below character: (a) obtained by Trichoderma (Trichoderma spp); (b) approximate molecular weight is 22-27kDa; (c) iso-electric point is 7.2-8.0; (d) best pH is 5.5-6.0.

5. according to the laundry detergent composition of claim 1-4, the content of wherein said cellulase is for pressing general composition weight meter 0.0001%-0.1%, preferred 0.0005%-0.05%, the more preferably pure enzyme of 0.001%-0.01%.

6. according to the laundry detergent composition of claim 1-5, wherein the content of alkyl poly glucoside surfactant is for pressing general composition weight meter 0.1%-20%, preferred 1%-10%, more preferably 2%-8%.

7. according to the laundry detergent composition of above-mentioned arbitrary claim, wherein said alkyl poly glucoside surfactant has following formula:

R-O-G _xWherein R is average C ₈-C ₂₀, preferred C ₈-C ₁₆Alkyl, G are the parts that is obtained by the recuding sugars that contains 5-6 carbon atom, and preferred glucose unit and x are average 1.0-3.0, and the polymerization average degree of expression alkyl polysaccharide surfactant.

8. according to the laundry detergent composition of claim 7, wherein said alkyl poly glucoside surfactant contains 1-6, the hydrophilic segment of preferred 2-4 α or β pyranoside or furanoside anomer.

9. according to the laundry detergent composition of above-mentioned arbitrary claim, it also contains the conventional detergent enzyme that is selected from other cellulase, proteolytic enzyme, amylase and/or lipase.

10. according to the laundry detergent composition of claim 9, wherein said other cellulase is that DSM1800 obtains by Humicola insolens ^-The 43kD endoglucanase.

11. according to the laundry detergent composition of above-mentioned arbitrary claim, it is the form of additive.

12. alkyl poly glucoside surfactant and best pH are 4-10 and the purposes of fungal cellulase in laundry detergent composition that does not have cellulose binding domain, so that the outstanding washing and the whiteness impact of performance to be provided.

13. a fabric sofetening composition, it contains alkyl poly glucoside surfactant, best pH is 4-10 and the cats product that do not contain the fungal cellulase of cellulose binding domain and contain two long-chains.