CN1250245C - Capsule for treating osteonecrosis and bone fracture - Google Patents
Capsule for treating osteonecrosis and bone fracture Download PDFInfo
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- CN1250245C CN1250245C CNB2003101076014A CN200310107601A CN1250245C CN 1250245 C CN1250245 C CN 1250245C CN B2003101076014 A CNB2003101076014 A CN B2003101076014A CN 200310107601 A CN200310107601 A CN 200310107601A CN 1250245 C CN1250245 C CN 1250245C
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- grams
- capsule
- bone
- beniol
- osteonecrosis
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- 206010031264 Osteonecrosis Diseases 0.000 title claims abstract description 19
- 239000002775 capsule Substances 0.000 title claims abstract description 17
- 208000010392 Bone Fractures Diseases 0.000 title abstract description 17
- 239000003814 drug Substances 0.000 claims abstract description 23
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 5
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 5
- 241001550206 Colla Species 0.000 claims description 8
- 239000002994 raw material Substances 0.000 claims description 5
- 241000209020 Cornus Species 0.000 claims description 4
- 241000283956 Manis Species 0.000 claims description 4
- 241001057584 Myrrha Species 0.000 claims description 4
- 241000237636 Pheretima Species 0.000 claims description 4
- 241001489978 Eupolyphaga Species 0.000 claims description 3
- 239000000843 powder Substances 0.000 claims description 3
- 239000012467 final product Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 18
- 206010017076 Fracture Diseases 0.000 abstract description 17
- 210000000988 bone and bone Anatomy 0.000 abstract description 13
- 230000006378 damage Effects 0.000 abstract description 7
- 239000008280 blood Substances 0.000 abstract description 6
- 230000017531 blood circulation Effects 0.000 abstract description 6
- 230000001737 promoting effect Effects 0.000 abstract description 6
- 210000004369 blood Anatomy 0.000 abstract description 5
- 210000000845 cartilage Anatomy 0.000 abstract description 5
- 201000010099 disease Diseases 0.000 abstract description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 5
- 210000003734 kidney Anatomy 0.000 abstract description 5
- 206010028851 Necrosis Diseases 0.000 abstract description 4
- 230000017074 necrotic cell death Effects 0.000 abstract description 4
- 230000035876 healing Effects 0.000 abstract description 3
- 230000004089 microcirculation Effects 0.000 abstract description 2
- 238000010792 warming Methods 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract 3
- 239000003292 glue Substances 0.000 abstract 2
- 241000131329 Carabidae Species 0.000 abstract 1
- 240000007311 Commiphora myrrha Species 0.000 abstract 1
- 235000006965 Commiphora myrrha Nutrition 0.000 abstract 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
- 241000361919 Metaphire sieboldi Species 0.000 abstract 1
- 235000007265 Myrrhis odorata Nutrition 0.000 abstract 1
- 241000237502 Ostreidae Species 0.000 abstract 1
- 241000283966 Pholidota <mammal> Species 0.000 abstract 1
- 240000007164 Salvia officinalis Species 0.000 abstract 1
- 241000270708 Testudinidae Species 0.000 abstract 1
- 241001482963 Thamnophis Species 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 229910052802 copper Inorganic materials 0.000 abstract 1
- 239000010949 copper Substances 0.000 abstract 1
- 235000020636 oyster Nutrition 0.000 abstract 1
- 235000005412 red sage Nutrition 0.000 abstract 1
- 239000002689 soil Substances 0.000 abstract 1
- 208000007875 Femur Head Necrosis Diseases 0.000 description 9
- 229940079593 drug Drugs 0.000 description 5
- 210000004185 liver Anatomy 0.000 description 5
- 230000003203 everyday effect Effects 0.000 description 3
- 108010048734 sclerotin Proteins 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 230000010478 bone regeneration Effects 0.000 description 2
- 210000004394 hip joint Anatomy 0.000 description 2
- 210000003141 lower extremity Anatomy 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 230000002269 spontaneous effect Effects 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 230000035900 sweating Effects 0.000 description 2
- 208000027502 Ankle fracture Diseases 0.000 description 1
- 206010016997 Forearm fracture Diseases 0.000 description 1
- 206010017577 Gait disturbance Diseases 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 206010020649 Hyperkeratosis Diseases 0.000 description 1
- 206010034122 Patella fracture Diseases 0.000 description 1
- 206010061363 Skeletal injury Diseases 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 210000001624 hip Anatomy 0.000 description 1
- 210000001981 hip bone Anatomy 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 230000005499 meniscus Effects 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 230000001314 paroxysmal effect Effects 0.000 description 1
- 230000002688 persistence Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 210000005065 subchondral bone plate Anatomy 0.000 description 1
- 210000004233 talus Anatomy 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
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- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses a bone beniol capsule of a traditional Chinese medicament for curing necrosis of femoral head, which is composed of the following raw medicinal materials and weight proportioning: 45 to 50 grams of garter snakes, 35 to 40 grams of pangolin scale, 30 to 35 grams of notoginseng, 30 to 35 grams of earthworm, 40 to 45 grams of keel, 30 to 35 grams of oysters, 30 to 35 grams of glue of tortoise plastron, 40 to 45 grams of deerhorn glue, 50 to 55 grams of red sage roots and 15 to 20 grams of myrrh. The raw medicinal materials are pulverized and porphyrized to be prepared into capsules. The bone beniol capsule has the functions of warming meridian, removing blood stasis, dredging the meridian passage, nourishing blood, invigorating the kidney, activating blood circulation to stop pain and promoting microcirculation to repair and regenerate sequestrum. The bone beniol capsule can effectively cure the necrosis of femoral head and other diseases of osteonecrosis, cartilage, bone scale damage, etc. After native copper and ground beetle soil are added to the raw medicinal materials, the bone beniol capsule has a better curative effect on osseous healing after coaptation is carried out to fracture patients.
Description
Technical field
The present invention relates to a kind of medical technical field, be specifically related to a kind of Chinese medicine for the treatment of femur head necrosis and other osteonecrosis.
Background technology
Femur head necrosis is a kind of frequently-occurring disease of serious harm human health, sickness rate is ascendant trend year by year, it is one of world's orthopaedics pertinacious disease, orthopedics circle adopts the boring decompression more both at home and abroad, multiple operation methods such as blood vessel grafting, free bone grafting operation, osteotomy, artificial joint replacement, above-mentioned Therapeutic Method effect is unsatisfactory.Domestic in recent years a lot of scholars adopt pure treatment by Chinese herbs femur head necrosis, but generally exist the course of treatment long, the inapparent shortcoming of curative effect.
Summary of the invention
The object of the present invention is to provide a kind of capsule for the treatment of osteonecrosis and fracture, can treat the damage of femur head necrosis and other osteonecrosis, cartilage and bone dirt effectively, this Chinese medicine to synthetism after the healing of sclerotin better therapeutic is arranged.
Crude drug of the present invention selects Zaocys, Squama Manis, Radix Notoginseng, Pheretima, Os Draconis, Concha Ostreae, Colla Plastri Testudinis, Colla cornus cervi, Radix Salviae Miltiorrhizae, Myrrha to make up, these drug regimens make each efficacy of drugs produce synergism, thereby can effectively treat femur head necrosis and diseases such as other osteonecrosis, cartilage and the damage of bone dirt.Wherein select Zaocys for use, have the deep wind of searching, nowhere less than, the effect of dispelling, collateral-activating; Squama Manis has promoting blood circulation to restore menstrual flow, is apt to away scurry, and property specially row is loose, and the meridian dredging reaches the effect of disease institute; Radix Notoginseng has removing stasis to stop bleeding, the effect of the analgesic therapy of invigorating blood circulation; Pheretima, salty-cold, return liver spleen urinary bladder channel, have the effect of clearing heat for calming endogenous wind, collateral dredging; Os Draconis have suppressing the hyperactive liver and subsiding YANG, and tranquillizing and allaying excitement is restrained astringent or styptic treatment for spontaneous sweating effect; Concha Ostreae, suppressing the hyperactive liver and subsiding YANG is restrained astringent or styptic treatment for spontaneous sweating effect; Colla Plastri Testudinis has nourishing YIN for suppressing the hyperactive YANG, the effect of replenishing kidney and strengthening bone; Colla cornus cervi has invigorating the liver and kidney, benefiting essence-blood, hemostasis, the effect of the sick bone and muscle strengthening of the kidney invigorating; Radix Salviae Miltiorrhizae has the effect of blood circulation promoting and blood stasis dispelling; Myrrha, GUIXIN liver spleen channel has promoting blood circulation and stopping pain, the effect of detumescence and promoting granulation.
A kind of capsule for the treatment of osteonecrosis and fracture of the present invention is made up of following raw material medicaments and weight proportion: Zaocys 45-50g, Squama Manis 35-40g, Radix Notoginseng 30-35g, Pheretima 30-35g, Os Draconis 40-45g, Concha Ostreae 30-35g, Colla Plastri Testudinis 30-35g, Colla cornus cervi 40-45g, Radix Salviae Miltiorrhizae 50-55g, Myrrha 15-20g.
With the broken porphyrize of above-mentioned raw materials medicated powder, it is for oral administration to make capsule or powder.Every day 2-3 time, each dose is the 1-1.5 gram.
Each crude drug compatibility of the present invention has warming the meridian blood stasis dispelling, dredge the meridian passage, blood nourishing and kidney tonifying, and promoting blood circulation and stopping pain promotes microcirculation, the effect that makes sequestrum be repaired and regenerate.The capsule that the present invention treats osteonecrosis and fracture can be treated femur head necrosis and other osteonecrosis and cartilage and the damage of bone dirt, the destruction of sclerotin and necrosis is had repair and the regeneration effect, and better therapeutic effect can be arranged in a short time.
The present invention selects Pyritum, eliminating stasis to stop pain, the effect that synthetism is cured the wound; Eupolyphaga Seu Steleophaga, strong muscle synthetism, the effect of the pain relieving of curing the wound.In crude drug of the present invention, add Pyritum 50-55g, Eupolyphaga Seu Steleophaga 45-50g, be used for the treatment of the sclerotin healing after the fracture, evident in efficacy.
The specific embodiment
One, uses a kind of capsule for the treatment of osteonecrosis and fracture of the present invention that femur head necrosis, other osteonecrosis and bone injury patient are carried out clinical practice, all reach promising result.
1. case is selected.Accept femur head necrosis 60 examples for medical treatment, the age is between 13～60 years old.
2. diagnostic criteria.According to clinical manifestation and the diagnosis of X ray examination.1,2 phases: hip is asymptomatic, and X-ray film femoral head density has slightly or obviously and increases.3 phases: symptom is slight, X-ray film femoral head at weight loading region subchondral bone folding or meniscus sign; 4 phases: hipbone pain, be paroxysmal or persistence, broken row and function limitation, the X-ray film femoral head is flat or subside.
3. Therapeutic Method.Take the capsule that the present invention treats osteonecrosis, every day 2-3 time, each 1-1.5 gram.
4. curative effect determinate standard.Cure: walking does not have limping, and hip joint does not have pain, and lower limb function recovers normally substantially, and X-ray film femoral head sequestrum district, osteonecrosis and bone regeneration hardening phenomenon have improvement.Effectively: sx, the hip joint movable function improves, and the lower limb cripetura is about 1 centimetre, and X-ray film shows that femoral head becomes big or flat, but osteonecrosis and bone regeneration hardening phenomenon have improvement.Invalid: symptom does not have improvement, and X-ray film sign does not have change.
5. clinical therapeutic efficacy.60 routine femur head necrosis patients, 1,2 phase patients take medicine 3-4 month effectively, can cure in 6-12 month, and 3 phase patients take medicine and cured in 12-18 month, and 4 phase patients take medicine and cured in 18-24 month, cure 52 examples altogether, 5 examples that take a turn for the better, and invalid 3 examples, total effective rate reaches 95%.
In addition, the capsule that the present invention treats osteonecrosis and fracture is used for the treatment of cartilage and bone dirt damage patient 4 examples, and symptom obviously alleviates after 1 month, and limitation of activity improves, and cures in 3 months.Treatment hands moon osteonecrosis 3 examples, sufficient talus necrosis 1 example was all cured in 6-9 month.
Two, use Chinese medicine of the present invention that fracture patient has been carried out clinical practice, all reach satisfied effect.
Confirm 100 routine fracture patients through X-ray examination, the oldest person 83 years old, reckling 3 years old is taken the Chinese medicine that the present invention is used for fracture patient after the operation, every day 2-3 time, each 1-1.5 gram.Wherein forearm fracture 12 examples were taken fracture of upper arm 8 examples Chinese medicine 21-40 of the present invention days, took Chinese medicine 40-50 of the present invention days, along tuberosity 11 examples of fracturing, took Ke Leishi 36 examples of fracturing Chinese medicine 40-52 of the present invention days, took Chinese medicine 24-32 of the present invention days, Patella fracture 3 examples were taken clavicular fracture 10 examples Chinese medicine 24-30 of the present invention days, took Chinese medicine 10-28 of the present invention days, ankle fracture 20 examples were taken Chinese medicine 30-40 of the present invention days, except that the suitable tuberosity fracture patient of 1 example, all reach clinical union of bone standard (local no pain, X-ray film shows that fracture line is fuzzy, continuous callus is arranged by fracture line, observes for two weeks continuously, indeformable person fractures), total effective rate reaches 99%.
Claims (2)
1, a kind of capsule for the treatment of osteonecrosis and fracture, it is characterized in that forming: Zaocys 45-50g, Squama Manis 35-40g, Radix Notoginseng 30-35g, Pheretima 30-35g, Os Draconis 40-45g, Concha Ostreae 30-35g, Colla Plastri Testudinis 30-35g, Colla cornus cervi 40-45g, Radix Salviae Miltiorrhizae 50-55g, Myrrha 15-20g by following raw material medicaments and weight proportion, with the broken porphyrize of above-mentioned raw materials medicated powder, make capsule and get final product.
2, a kind of capsule for the treatment of osteonecrosis and fracture according to claim 1 is characterized in that: can add Pyritum 50-55g, Eupolyphaga Seu Steleophaga 45-50g in the above-mentioned raw materials medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2003101076014A CN1250245C (en) | 2003-10-01 | 2003-10-01 | Capsule for treating osteonecrosis and bone fracture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2003101076014A CN1250245C (en) | 2003-10-01 | 2003-10-01 | Capsule for treating osteonecrosis and bone fracture |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1579478A CN1579478A (en) | 2005-02-16 |
| CN1250245C true CN1250245C (en) | 2006-04-12 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2003101076014A Expired - Fee Related CN1250245C (en) | 2003-10-01 | 2003-10-01 | Capsule for treating osteonecrosis and bone fracture |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1250245C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1318080C (en) * | 2005-04-01 | 2007-05-30 | 郭永昌 | Medicine used for treating osteonecrosis, femur ischemic osteonecrosis |
| CN1958027B (en) * | 2005-10-08 | 2011-01-26 | 刘国飞 | Composition of Chinese traditional medicine for treating necrosis of femoral head, and preparation method |
| CN101088534B (en) * | 2006-06-14 | 2011-01-05 | 宫恩年 | Medicine composition for treating bone necrosis and its preparation process |
-
2003
- 2003-10-01 CN CNB2003101076014A patent/CN1250245C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1579478A (en) | 2005-02-16 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20060412 Termination date: 20091102 |