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CN1248495A - Quick adjustable pipette - Google Patents

Quick adjustable pipette Download PDF

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Publication number
CN1248495A
CN1248495A CN 98119757 CN98119757A CN1248495A CN 1248495 A CN1248495 A CN 1248495A CN 98119757 CN98119757 CN 98119757 CN 98119757 A CN98119757 A CN 98119757A CN 1248495 A CN1248495 A CN 1248495A
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CN
China
Prior art keywords
housing
inner chamber
piston
rod
screw
Prior art date
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Pending
Application number
CN 98119757
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Chinese (zh)
Inventor
陈国君
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
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Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN 98119757 priority Critical patent/CN1248495A/en
Publication of CN1248495A publication Critical patent/CN1248495A/en
Pending legal-status Critical Current

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Abstract

The quick adjustable pipette includes shell body, piston tube pipette head lower spacer, first spring, regulating knob, spacing regulating screw arbor, second scale tube, piston component, second spring and regulating device which includes a cylindrical body with two radial screw holes inside which each is equipped with convex tooth meshed with external screw-thread of spacing regulating screw arbor. Besides, it also includes a positioning screw and a spring.

Description

Quick adjustable pipette
The present invention relates to a kind of pipettor, particularly a kind of quick adjustable pipette.
Pipettor is a kind of precision instrument that is used for transfer liquid, is widely used for fields such as chemistry, medical and health and biology.It is mainly by piston moving axially in plunger shaft, and the volume that changes plunger shaft is drawn or discharged liquid.Increase when moving axially of piston makes the plunger shaft space, the pressure in the plunger shaft reduces, and liquid enters the pipettor head that is attached thereto by the atmospheric pressure effect in the external world; Reduce when moving axially of piston makes the plunger shaft space, the pressure in the plunger shaft increases, and liquid is discharged from the pipettor head, finishes the transfer of liquid thus.Because the volume-variation of plunger shaft is controlled by piston and moves axially distance in plunger shaft, therefore comes control piston displacement by a pair of stop, just can reach the purpose of controlling liquid transfer amount.Distance between a pair of stop increases, and the distance that moves axially of piston then increases, and the transfer amount of liquid also increases; Otherwise the transfer amount of liquid then reduces.Existing adjustable pipette mostly is by rotating a pair of screw rod and nut, regulate the distance between a pair of stop, reaching the transfer amount of controlling liquid.Move the liquid precision for what keep pipettor, the general design of pitch smaller, like this, and when carrying out the transfer that twice liquid capacity differ greatly, must a large amount of rotary screws and nuts relatively.Especially carry out repeatedly liquid capacity when changing big transfer at needs, the adjustable pipette of this structure has brought very big inconvenience to the operator.
The purpose of this invention is to provide a kind of quick adjustable pipette, it can be fast and regulates distance between a pair of stop easily, thereby can be fast and the transfer amount of regulating liquid easily.
The objective of the invention is to be achieved through the following technical solutions, a kind of quick adjustable pipette comprises: a housing, comprise the upper shell and the lower house that removably are fixed together, the xsect of housing is oval, one opening is respectively arranged on the two side of its short-axis direction, on a sidewall of its long axis direction a display window is arranged, its round cavity comprises bigger top inner chamber and the less lower lumen of diameter of diameter that interconnects, and its upper surface and lower surface are equipped with the hole that is communicated with inner chamber; One piston cylinder, comprise the cylindrical shell and the cover that removably are fixed together, the upper end of piston cylinder removably is connected with the lower end of described housing, and its inner chamber is communicated with the inner chamber of housing, and its inner chamber lower end is in communication with the outside by a capillary channel, in the cylinder top inboard one annular groove is arranged; One pipettor head, its upper end removably is connected the lower end of described piston cylinder, and its inner chamber is communicated with the inner chamber of piston cylinder by described capillary channel, and there is an aperture that is in communication with the outside its lower end; One lower retainer comprises a cylindrical portions may and at this outward extending flange in cylindrical portions may lower end, and described flange is positioned in the annular groove of piston cylinder and can moves axially therein, and cylindrical portions may is positioned at the lower part of frame inner chamber; One first spring is positioned at the annular groove of piston cylinder, and the lower surface of the flange on its upper end and the lower retainer contacts, and its lower end contacts with the diapire of annular groove; One regulates knob, and it can be positioned in the top inner chamber of housing with moving axially, and comprise a center pit and be fixed on its lower end, lateral surface indicates first scale drum of circular scale; One spacing adjusting screw(rod), its upper end is fixed in the center pit of described adjusting knob, and its external diameter matches with the internal diameter of lower part of frame inner chamber, and comprises a central through hole and the screw thread on lateral surface; One second scale drum is fixed in the top inner chamber of housing, and its lateral surface indicates vertical scale, and its external diameter is less than the internal diameter of first scale drum; One piston component, comprise piston rod through housing upper end open, spacing adjusting screw(rod) central through hole and lower retainer cylindrical portions may, outward extending at this piston rod middle part, external diameter matches with the lower housing portion inner chamber, the defining flange between the upper surface of the lower surface of spacing adjusting screw(rod) and lower retainer, and this piston-rod lower end, can be in the piston cylinder inner chamber axially movable piston; One second spring is positioned in the lower part of frame inner chamber, and its upper end contacts with the lower surface of defining flange on the piston component, and its lower end contacts with the upper surface of piston cylinder; An and regulating device.And this regulating device comprises: a right cylinder, it has a center pit that allows spacing adjusting screw(rod) to pass through, with two apart from one another by, the vertical radially screw that also is communicated with this center pit, and this right cylinder and housing relative fixed; Two double wedges, they are slidably located on two inboards of screw radially respectively, and comprise respectively towards center pit, with the tip of the external thread engagement of spacing adjusting screw(rod); Two dog screws, they spin respectively and are fixed on two outsides of screw radially; And two springs, they lay respectively at two radially in the screw, and between a double wedge and a location screw.
Advantage of the present invention is, because regulating device and spacing adjusting screw(rod) are Elastic Meshing, thereby when rotating the adjusting knob gently, because of regulating device and spacing adjusting screw(rod) still are in engagement, so spacing adjusting screw(rod) will slowly move axially because of rotation, but thereby the distance between fine tuning spacing adjusting screw(rod) lower surface and the lower retainer upper surface, and then by the displacement of defining flange fine tuning piston in the piston cylinder inner chamber on the piston component, the transfer amount of final fine tuning liquid.When promptly regulating knob, firmly vertical moving is regulated knob, and then during the spacing adjusting screw(rod) of vertical moving, because the double wedge in the regulating device can stressedly be retracted into radially in the screw, so spacing adjusting screw(rod) moves rapid axial the transfer amount of quick adjustment liquid the most at last.
Describe one embodiment of the invention in detail below in conjunction with accompanying drawing, therefrom can more clearly understand the features and advantages of the present invention.
Fig. 1 is the longitudinal section of one embodiment of the invention;
Fig. 2 is the cut-open view along the A-A line among Fig. 1;
Fig. 3 is the enlarged drawing of the partial interior structure in the structure shown in Figure 1.
Referring to Fig. 1 to 3, quick adjustable pipette of the present invention is made up of following parts.One housing 3, comprise the upper shell 29 and the lower house 30 that removably are fixed together by screw (not shown) or other method, so that other parts are installed in housing, the xsect of housing is oval, one opening 19 is respectively arranged on the two side of its short-axis direction, one display window 14 is arranged on a sidewall of its long axis direction, and its round cavity comprises bigger top inner chamber and the less lower lumen of diameter of diameter that interconnects, and its upper surface and lower surface are equipped with the hole that is communicated with inner chamber.
One piston cylinder 11, comprise the cylindrical shell 31 and the cover 32 that removably are fixed together by screw (not shown) or other method, the upper end of piston cylinder removably is connected with the lower end of described housing 3 by an attaching nut 28, its inner chamber is communicated with the inner chamber of housing 3, and its inner chamber lower end is in communication with the outside by a capillary channel 20.In addition, in the inboard, top of cylindrical shell one annular groove 22 is arranged.
One pipettor head 13, its upper end removably is connected the lower end of described piston cylinder 11, and its inner chamber is communicated with the inner chamber of piston cylinder 11 by described capillary channel 20, and there is an aperture that is in communication with the outside 21 its lower end.
One lower retainer 10 comprises a cylindrical portions may and at the outward extending flange 23 in this cylindrical portions may lower end.Described flange 23 is positioned at 22 li of the annular grooves of piston cylinder and can moves axially therein, and cylindrical portions may extends into the lower lumen of housing 3.
One first spring 24 is positioned at the annular groove 22 of piston cylinder 11, and the lower surface of the flange 23 on its upper end and the lower retainer 10 contacts, and its lower end contacts with the diapire of annular groove 22, thereby upwards promotes lower retainer 10 all the time.
One regulates knob 4, and it is positioned in the top inner chamber of housing 3, and comprise a center pit and be fixed on its lower end, lateral surface indicates first scale drum 5 of circular scale.Operator's two fingers can pinch this adjusting knob 4 by two openings on housing 3 sidewalls, and it is rotated in the inner chamber of the top of housing or move axially.
One spacing adjusting screw(rod) 8, its upper end is fixed in the center pit of described adjusting knob 24, and its external diameter matches with the internal diameter of the lower lumen of housing 3, and comprises a central through hole and the screw thread on lateral surface.Distance between the upper surface of its lower surface and lower retainer 10 be a piston component described below displacement, when spacing adjusting screw(rod) 8 is mobile with regulating knob 4, distance between the upper surface of its lower surface and lower retainer 10 changes, thereby the displacement of piston component also changes.
One second scale drum 6 is fixed in the top inner chamber of housing 3, and its lateral surface indicates vertical scale, and its external diameter is less than the internal diameter of first scale drum 5.Vertical scale on the circular scale on first scale drum 5 and second scale drum 6 can be read by the display window on the housing 14, and their combination scale represents that this pipettor is with the liquid transfer amount of implementing.
One piston component 1, comprise piston rod 2 through housing 3 upper end open, spacing adjusting screw(rod) 8 central through holes and lower retainer 10 cylindrical portions may, outward extending at these piston rod 2 middle parts, external diameter matches with housing 3 lower lumen, the defining flange 9 between the upper surface of the lower surface of spacing adjusting screw(rod) 8 and lower retainer 10, and these piston rod 2 lower ends, can be in piston cylinder 11 inner chambers axially movable piston 12.Because the defining flange 9 on the piston component 1 can only move between the upper surface of the lower surface of spacing adjusting screw(rod) 8 and lower retainer 10, therefore distance also defines the displacement of piston 12 in piston cylinder 11 inner chambers between the upper surface of the lower surface of spacing adjusting screw(rod) 8 and lower retainer 10, finally defines the transfer amount of liquid.
One second spring 17 is positioned in the lower lumen of housing 3, and its upper end contacts with the lower surface of defining flange 9 on the piston component 1, and its lower end contacts with the upper surface of piston cylinder 11, thereby upwards promotes piston component 1 all the time.And
One regulating device 7, it comprises a right cylinder 25, and this right cylinder has a center pit 26 that allows spacing adjusting screw(rod) 8 to pass through, with two apart from one another by, with these center pit 26 vertical radially screws 27 that also are communicated with, and these right cylinder 25 and housing 3 relative fixed.Each radially 27 li of screws have one that be positioned at its inboard and have double wedge 15 towards the tip of center pit 26, spinning is fixed on the radially dog screw 18 in screw 27 outsides, and between double wedge 15 and dog screw 18 spring 16.Spring 16 always outwards promotes double wedge 15, makes the external thread Elastic Meshing of itself and spacing adjusting screw(rod) 8.
Introduce the using method of quick adjustable pipette provided by the invention below.Under normal circumstances, pipettor is in position shown in Figure 1.In the time will moving liquid, pipettor head 13 is immersed in the liquid that will shift, promote piston component 1 then downwards, piston component 1 will overcome the elastic force of second spring 17 and move down, the gas that piston 12 is discharged in piston cylinder 11 inner chambers.When the defining flange on the piston component 19 was run into the upper surface of lower retainer 10, piston component 1 (comprising piston 12) stopped to move.Then, operator's hand leaves piston component 1, piston component 1 moves up under the effect of second spring 17, thereby driving piston 12 moves up, make the inner chamber of piston cylinder 11 and then make the inner chamber of pipettor head 13 form negative pressure, thus, make the liquid that will shift under the atmospheric effect in the external world, enter pipettor head inner chamber by aperture 21.When the defining flange on the piston component 19 was run into the lower surface of spacing adjusting screw(rod) 8, piston component 1 (comprising piston 12) stopped to move, and the imbibition process finishes immediately.At this moment, the amount of liquid of suction promptly is the transfer amount of liquid.In the time will changing the transfer amount of liquid on a small quantity, can rotate gently and regulate knob 4, since the double wedge 15 in the regulating device 7 still with the external thread engagement of spacing adjusting screw(rod) 8, therefore, spacing adjusting screw(rod) 8 can only slowly move axially along with rotation, thereby but the distance between fine tuning spacing adjusting screw(rod) 8 lower surfaces and lower retainer 7 upper surfaces changes the distance that moves axially of piston component 1, finally changes the liquid transfer amount of pipettor.In the time will changing the transfer amount of liquid in a large number, can tightly pinch and regulate knob 4, firmly vertical moving it, at this moment, double wedge in the regulating device 7 15 is stressed to be retracted into radially 27 li of screws, thereby breaks away from the engagement with spacing adjusting screw(rod) 8, make spacing adjusting screw(rod) 8 vertical fast moving, change the distance between spacing adjusting screw(rod) 8 lower surfaces and lower retainer 7 upper surfaces rapidly, change the distance that moves axially of piston component 1, the final liquid transfer amount that changes pipettor rapidly.

Claims (1)

1. quick adjustable pipette comprises:
One housing (3), comprise the upper shell (29) and the lower house (30) that removably are fixed together, the xsect of housing is oval, one opening (19) is respectively arranged on the two side of its short-axis direction, one display window (14) is arranged on a sidewall of its long axis direction, its round cavity comprises bigger top inner chamber and the less lower lumen of diameter of diameter that interconnects, and its upper surface and lower surface are equipped with the hole that is communicated with inner chamber;
One piston cylinder (11), comprise the cylindrical shell (31) and the cover (32) that removably are fixed together, the upper end of piston cylinder removably is connected with the lower end of described housing (3), its inner chamber is communicated with the inner chamber of housing (3), and its inner chamber lower end is in communication with the outside by a capillary channel (20), and an annular groove (22) is arranged in the cylinder top inboard;
One pipettor head (13), its upper end removably is connected the lower end of described piston cylinder (11), and its inner chamber is communicated with the inner chamber of piston cylinder (11) by described capillary channel (20), and there is an aperture that is in communication with the outside (21) its lower end;
One lower retainer (10), comprise a cylindrical portions may and at the outward extending flange in this cylindrical portions may lower end (23), described flange (23) is positioned at annular groove (22) lining of piston cylinder and can moves axially therein, and cylindrical portions may is positioned at the lower lumen of housing (3);
One first spring (24) is positioned at the annular groove (22) of piston cylinder (11), and the lower surface of the flange (23) on its upper end and the lower retainer (10) contacts, and its lower end contacts with the diapire of annular groove (22);
One regulates knob (4), and it can be positioned in the top inner chamber of housing (3) with moving axially, and comprise a center pit and be fixed on its lower end, lateral surface indicates first scale drum (5) of circular scale;
One spacing adjusting screw(rod) (8), its upper end is fixed in the center pit of described adjusting knob (24), and its external diameter matches with the internal diameter of the lower lumen of housing (3), and comprises a central through hole and the screw thread on lateral surface;
One second scale drum (6) is fixed in the top inner chamber of housing (3), and its lateral surface indicates vertical scale, and its external diameter is less than the internal diameter of first scale drum (5);
One piston component (1), comprise piston rod (2) through housing (3) upper end open, spacing adjusting screw(rod) (8) central through hole and lower retainer (10) cylindrical portions may, outward extending at this piston rod (2) middle part, external diameter matches with housing (3) lower lumen, the defining flange (9) between the upper surface of the lower surface of spacing adjusting screw(rod) (8) and lower retainer (10), and this piston rod (2) lower end, can be in piston cylinder (11) inner chamber axially movable piston (12);
One second spring (17) is positioned in the lower lumen of housing (3), and its upper end contacts with the lower surface of defining flange (9) on the piston component (1), and its lower end contacts with the upper surface of piston cylinder (11); And
One regulating device (7), it is fixed in the top inner chamber of housing (3), and with the engagement of the external thread of spacing adjusting screw(rod) (8);
It is characterized in that: described regulating device (7) comprising:
One right cylinder (25), it has a center pit (26) that allows spacing adjusting screw(rod) (8) to pass through, with two apart from one another by, the vertical radially screw (27) that also is communicated with this center pit (26), this right cylinder (25) and housing (3) relative fixed;
Two double wedges (15), they are slidably located on two inboards of screw (27) radially respectively, and comprise respectively towards center pit (26), with the tip of the external thread engagement of spacing adjusting screw(rod) (8);
Two dog screws (18), they spin respectively and are fixed on two outsides of screw (27) radially; And
Two springs (16), they lay respectively at two screw (27) linings radially, and are positioned between a double wedge (15) and the location screw (18).
CN 98119757 1998-09-22 1998-09-22 Quick adjustable pipette Pending CN1248495A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 98119757 CN1248495A (en) 1998-09-22 1998-09-22 Quick adjustable pipette

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 98119757 CN1248495A (en) 1998-09-22 1998-09-22 Quick adjustable pipette

Publications (1)

Publication Number Publication Date
CN1248495A true CN1248495A (en) 2000-03-29

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN 98119757 Pending CN1248495A (en) 1998-09-22 1998-09-22 Quick adjustable pipette

Country Status (1)

Country Link
CN (1) CN1248495A (en)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1331609C (en) * 2004-05-28 2007-08-15 中国农业大学 Quantitative liquid extraction device
CN101850279A (en) * 2010-06-10 2010-10-06 上海理工大学 A device that assists a pipette to facilitate the transfer of liquids
CN103235147A (en) * 2005-12-21 2013-08-07 梅索斯卡莱科技公司 Assay apparatuses, methods and reagents
CN103874546A (en) * 2011-09-19 2014-06-18 吉尔松有限合伙公司 Positive-displacement pipette having an improved ejection function
CN103990502A (en) * 2012-11-23 2014-08-20 埃佩多夫股份公司 Multichannel pipette
CN105181390A (en) * 2011-09-23 2015-12-23 美艾利尔瑞士公司 System And Apparatus For Reactions
CN105705241A (en) * 2013-11-07 2016-06-22 吉尔松有限合伙公司 Positive displacement pipetting system with piston design for easy gripping of capillary-piston assemblies
CN106470760A (en) * 2014-07-04 2017-03-01 埃佩多夫股份公司 Pipettor for operating syringe
CN107530702A (en) * 2015-04-16 2018-01-02 因特格拉生物科学股份公司 Capacity regulating for Manual liquid transfering device
CN109562372A (en) * 2016-06-15 2019-04-02 汉密尔顿公司 Pipetting devices, pipette tip couplers and pipette tips: devices and methods
CN111408418A (en) * 2019-01-07 2020-07-14 苏州赛尼特格尔实验室科技有限公司 Electronic pipettor and precision control method thereof
CN114669340A (en) * 2022-03-25 2022-06-28 上海科进生物技术有限公司 a hand-held pipette

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1331609C (en) * 2004-05-28 2007-08-15 中国农业大学 Quantitative liquid extraction device
CN103235147B (en) * 2005-12-21 2015-08-12 梅索斯卡莱科技公司 The liquid distributor of analytical equipment
US11892455B2 (en) 2005-12-21 2024-02-06 Meso Scale Technologies, Llc. Assay apparatuses, methods and reagents
CN103235147A (en) * 2005-12-21 2013-08-07 梅索斯卡莱科技公司 Assay apparatuses, methods and reagents
US11300571B2 (en) 2005-12-21 2022-04-12 Meso Scale Technologies, Llc. Assay apparatuses, methods and reagents
US12306190B2 (en) 2005-12-21 2025-05-20 Meso Scale Technologies, Llc. Assay apparatuses, methods and reagents
CN101850279B (en) * 2010-06-10 2012-06-13 上海理工大学 Device for assisting pipette to conveniently transfer liquid
CN101850279A (en) * 2010-06-10 2010-10-06 上海理工大学 A device that assists a pipette to facilitate the transfer of liquids
CN103874546A (en) * 2011-09-19 2014-06-18 吉尔松有限合伙公司 Positive-displacement pipette having an improved ejection function
CN103874546B (en) * 2011-09-19 2016-08-31 吉尔松有限合伙公司 There is the positive displacement pipette of the ejecting function of improvement
CN105181390B (en) * 2011-09-23 2019-07-16 美艾利尔瑞士公司 System and device for reaction
CN105181390A (en) * 2011-09-23 2015-12-23 美艾利尔瑞士公司 System And Apparatus For Reactions
CN103990502A (en) * 2012-11-23 2014-08-20 埃佩多夫股份公司 Multichannel pipette
CN103990502B (en) * 2012-11-23 2016-10-26 埃佩多夫股份公司 Multi-channel liquid transfer device
CN105705241A (en) * 2013-11-07 2016-06-22 吉尔松有限合伙公司 Positive displacement pipetting system with piston design for easy gripping of capillary-piston assemblies
US10507463B2 (en) 2014-07-04 2019-12-17 Eppendorf Ag Pipette for activating a syringe
CN106470760B (en) * 2014-07-04 2019-06-07 埃佩多夫股份公司 Pipettes for operating syringes
CN106470760A (en) * 2014-07-04 2017-03-01 埃佩多夫股份公司 Pipettor for operating syringe
CN107530702B (en) * 2015-04-16 2019-06-11 因特格拉生物科学股份公司 Volume adjustment for manual pipettes
CN107530702A (en) * 2015-04-16 2018-01-02 因特格拉生物科学股份公司 Capacity regulating for Manual liquid transfering device
CN110433885A (en) * 2016-06-15 2019-11-12 汉密尔顿公司 Pipetting devices, pipette tip couplers and pipette tips: devices and methods
CN110433885B (en) * 2016-06-15 2021-04-13 汉密尔顿公司 Pipetting device, pipette tip coupler and pipette tip: apparatus and method
CN109562372A (en) * 2016-06-15 2019-04-02 汉密尔顿公司 Pipetting devices, pipette tip couplers and pipette tips: devices and methods
CN111408418A (en) * 2019-01-07 2020-07-14 苏州赛尼特格尔实验室科技有限公司 Electronic pipettor and precision control method thereof
CN114669340A (en) * 2022-03-25 2022-06-28 上海科进生物技术有限公司 a hand-held pipette
CN114669340B (en) * 2022-03-25 2023-09-26 上海科进生物技术有限公司 a handheld pipette

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