CN113476692A - Infusion pump based on electromagnetic propulsion and micro-flow detection control - Google Patents
Infusion pump based on electromagnetic propulsion and micro-flow detection control Download PDFInfo
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- CN113476692A CN113476692A CN202110878455.3A CN202110878455A CN113476692A CN 113476692 A CN113476692 A CN 113476692A CN 202110878455 A CN202110878455 A CN 202110878455A CN 113476692 A CN113476692 A CN 113476692A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/1454—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons spring-actuated, e.g. by a clockwork
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/16886—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body for measuring fluid flow rate, i.e. flowmeters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3334—Measuring or controlling the flow rate
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
本发明公开了一种基于电磁推进和微流量检测控制的输注泵，包括壳体、电源及控制电路、储药器以及具有微流孔和鲁尔接头的输注接头，所述壳体包括壳体本体，壳体本体具有一个容纳储药器用的储药器腔体，储药器底部设置有一个储药器动力源，通过储药器动力源实现储药器的抽液以及输注，具有微流孔和鲁尔接头的输注接头安装于储药器上。本发明摈弃了传统的基于推杆的推进输注模式，省去电机、减速器件以及推杆，利用电磁作用力作为推进动力，同时利用微流和液压检测作为药液输注控制机制，从而进行小型化和微型化设计，可以充分利用泵体内部空间，对储药器及其他部件灵活设计和布局，解决了药液储量与空间利用率之间的矛盾。The invention discloses an infusion pump based on electromagnetic propulsion and micro-flow detection control. The shell body has a medicine storage cavity for accommodating the medicine storage, and a medicine storage power source is arranged at the bottom of the medicine storage, and the liquid extraction and infusion of the medicine storage are realized through the medicine storage power source. An infusion connector with a microfluidic orifice and a luer is mounted on the reservoir. The present invention abandons the traditional push rod-based infusion mode, omits the motor, the deceleration device and the push rod, uses the electromagnetic force as the propulsion power, and uses the micro-flow and hydraulic pressure detection as the liquid medicine infusion control mechanism, so as to carry out The miniaturization and miniaturization design can make full use of the internal space of the pump body, and flexibly design and layout the medicine storage and other components, which solves the contradiction between the liquid medicine storage and the space utilization rate.
Description
Technical Field
The invention relates to an infusion pump, in particular to an infusion pump based on electromagnetic propulsion and micro-flow detection control.
Background
At present, a speed reduction motor (a direct current motor or a stepping motor) is mostly used in various medical application type infusion pumps (such as an insulin infusion pump, a pituitary hormone infusion pump and the like) to drive a screw rod to push a medicine storage device to realize liquid medicine infusion, and the main structure of the medical application type infusion pump is shown in fig. 1.
When the infusion pump works, the medicine storage device filled with the liquid medicine is arranged in the fixed container and is in close contact with the screw rod through the piston, and the speed reduction motor drives the sliding screw nut to rotate through the gear. Because the screw nut is in a fixed state, the screw rod drives the piston to push forwards under the driving of the screw nut under the reaction force of the screw nut, and the rotary motion of the motor is converted into linear motion, so that the infusion operation of the liquid medicine is realized.
According to the principle analysis of the traditional infusion pump, the traditional infusion pump has the following defects in practical application:
1. the space utilization rate is low.
Because the length of the screw rod is required to be larger than or equal to the length of the medicine storage device, the liquid medicine can be ensured to be infused completely, which means that at least half of the space is occupied by the screw rod propelling mechanism, so that the liquid medicine can not be stored, the liquid medicine storage capacity is low, the space utilization rate of the infusion pump is low, and the waste is serious.
2. Infusion accuracy is difficult to improve.
This kind of medicine storage device contains two major functions of storing up medicine and injection in fact, because the storage dose can not too low, therefore medicine storage device often the sectional area is great, need carry out micro-infusion just must improve gear motor's speed reduction ratio, reduces lead screw silk apart from, but too big lead to the lead screw thrust too big easily of speed reduction ratio, therefore pipeline pressure is great, aggravation is suffered from the pain and is felt.
3. The pump body layout is difficult.
The whole infusion pump comprises a medicine storage device, a propelling mechanism, a speed reduction motor, a circuit board, power supply and other parts, and the medicine storage device and the propelling and injecting mechanism are bound, so that the flexibility of the mechanical structure design of the pump body is reduced, and the optimal design cannot be achieved.
4. The power loss is large.
The traditional mechanical propulsion mechanism and the traditional speed reducing mechanism have low transmission efficiency and large power loss, and especially in the process of converting rotary motion into linear motion, a large amount of energy is converted into friction force and is lost through a heat energy mode, and the power utilization rate is extremely low.
5. The mechanical noise is large.
Because there are motor and mechanical mechanism, the vibration of motor and gear rotation in-process produces the noise easily, not only influences patient's life and work and rest, also reveals patient's privacy easily.
Disclosure of Invention
The invention aims to solve the technical problem that an infusion pump based on electromagnetic propulsion and micro-flow detection control discards the traditional propulsion and infusion mode based on a push rod, saves a motor, a speed reducer and the push rod, utilizes electromagnetic acting force as propulsion power, and simultaneously utilizes micro-flow and hydraulic detection as a liquid medicine infusion control mechanism, thereby carrying out miniaturization and microminiaturization design, fully utilizing the internal space of a pump body, flexibly designing and arranging a medicine storage device and other components, and solving the contradiction between the liquid medicine storage quantity and the space utilization rate.
The invention is realized by the following technical scheme: an infusion pump based on electromagnetic propulsion and micro-flow detection control comprises a shell, a power supply and control circuit, a medicine storage device and an infusion joint with a micro-flow hole and a luer joint, wherein the shell comprises a shell body, the shell body is provided with a medicine storage device cavity for accommodating the medicine storage device, a power supply of the medicine storage device is arranged at the bottom of the medicine storage device, liquid pumping and infusion of the medicine storage device are realized through the power supply of the medicine storage device, the infusion joint with the micro-flow hole and the luer joint is arranged on the medicine storage device, and the power supply and control circuit are arranged in the shell body; the device also comprises a hydraulic detection sensor which is communicated with the liquid medicine in the cavity of the medicine storage device and is used for detecting the current pressure of the liquid medicine and converting the pressure value into a voltage or current value to be transmitted to the control circuit.
According to a preferable technical scheme, the power source of the medicine storage device comprises an electromagnetic coil and a piston containing a permanent magnet, the electromagnetic coil is tightly wound on a cavity of the medicine storage device, a magnetic field is generated in the electromagnetic coil after the electromagnetic coil is electrified and interacts with the permanent magnet in the piston to push the piston to move, infusion is started and ended by controlling on-off of current of a coil, the permanent magnet is fixed on the piston, and the piston is pushed to advance when acting force from the electromagnetic coil is applied.
As preferred technical scheme, the casing body is a totally closed structure, and its top is just being provided with magnetism to inhale formula and fill the interface soon to power and control circuit's position, uses jointly with supporting charger, carries out quick charge for infusion pump inner rechargeable battery, and the one side that is located storage medicine ware cavity still is provided with the sensor tie point for connect hydraulic pressure detection sensor and internal control circuit, make internal control circuit can acquire the liquid medicine pressure in the current storage medicine ware in real time.
As the preferred technical scheme, the top of the medicine storage device cavity is opened and is provided with an internal thread structure and a vertical slot for accommodating and fixing the medicine storage device.
As a preferred technical scheme, the power supply and the control circuit are composed of a charging circuit, an MCU and a detection circuit, and a vibrating motor or a buzzer.
As the preferred technical scheme, a hydraulic pressure detection sensor is installed on one side of the top of the medicine storage device, a contact reed is arranged on one side of the hydraulic pressure detection sensor and connected with the hydraulic pressure detection sensor, and when the medicine storage device is installed in the shell body, the contact reed is extruded by a sensor connection point on the shell and is in close contact with the sensor connection point to establish an electric path.
Preferably, the contact spring is a circular arc-shaped elastic metal sheet.
As the preferred technical scheme, the top of the medicine storage device is provided with a luer connector which is used for matching with a medicine pumping connector or an infusion connector.
As the preferred technical scheme, contain the miniflow hole chip in the infusion connects for communicate medicine storage device and infusion pipeline, the miniflow hole has < 5 um's internal diameter, is used for realizing the infusion control of trace liquid medicine.
Compared with the traditional infusion pump, the invention has the following advantages:
1. the infusion precision is high; in the invention, the micro-flow hole is used as a liquid medicine infusion channel, the inner diameter of the micro-flow hole can be as small as 5um, and compared with the traditional infusion pipeline, the liquid medicine flow in a unit time under the same hydraulic pressure can be as small as 2 orders of magnitude.
2. The volume is very small; the invention cancels the traditional mechanical propelling mechanism, thereby greatly reducing the volume of the pump body on the premise of keeping enough dosage and being convenient for a user to wear.
3. Extremely high waterproof and dustproof standards; because the casing of the infusion pump is completely closed and the medicine storage device is pushed by non-contact electromagnetic force, the invention can reach the extremely high waterproof and dustproof standard
4. No noise is generated; because no mechanical propulsion mechanism exists, no noise is generated in the infusion process, and the privacy is good.
5. Very high infusion accuracy; because the micro-fluidic technology and the micro-fluidic chip are utilized, precise infusion and micro-infusion can be realized.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic structural diagram of a conventional product;
FIG. 2 is a schematic view of the overall structure of the present invention;
FIG. 3 is a schematic structural view of the housing of the present invention;
FIG. 4 is a schematic structural view of the medicine storage device of the present invention;
FIG. 5 is a schematic structural view of an infusion connector of the present invention;
FIG. 6 is a schematic view of the present invention illustrating the drawing of medical fluid;
FIG. 7 is a schematic view of the infusion of medical fluids in accordance with the present invention;
FIG. 8 is a schematic timing diagram of the infusion of medical fluids in accordance with the present invention;
FIG. 9 is a schematic view of the construction of the liquid extraction adapter of the present invention.
Detailed Description
All of the features disclosed in this specification, or all of the steps in any method or process so disclosed, may be combined in any combination, except combinations of features and/or steps that are mutually exclusive.
Any feature disclosed in this specification (including any accompanying claims, abstract and drawings), may be replaced by alternative features serving equivalent or similar purposes, unless expressly stated otherwise. That is, unless expressly stated otherwise, each feature is only an example of a generic series of equivalent or similar features.
In the description of the present invention, it is to be understood that the terms "one end", "the other end", "outside", "upper", "inside", "horizontal", "coaxial", "central", "end", "length", "outer end", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are used only for convenience in describing the present invention and for simplicity in description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed in a particular orientation, and be operated, and thus, should not be construed as limiting the present invention.
Further, in the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.
The use of terms such as "upper," "above," "lower," "below," and the like in describing relative spatial positions herein is for the purpose of facilitating description to describe one element or feature's relationship to another element or feature as illustrated in the figures. The spatially relative positional terms may be intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "below" or "beneath" other elements or features would then be oriented "above" the other elements or features. Thus, the exemplary term "below" can encompass both an orientation of above and below. The device may be otherwise oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly
In the present invention, unless otherwise explicitly specified or limited, the terms "disposed," "sleeved," "connected," "penetrating," "plugged," and the like are to be construed broadly, e.g., as a fixed connection, a detachable connection, or an integral part; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
As shown in fig. 2, the infusion pump based on electromagnetic propulsion and micro-flow detection control of the present invention comprises a housing 1, a power supply and control circuit 2, a drug reservoir 4 and an infusion connector 5 with a micro-flow hole and a luer connector, wherein the housing 1 comprises a housing body, the housing body is provided with a drug reservoir cavity for accommodating the drug reservoir, the bottom of the drug reservoir is provided with a drug reservoir power source, the drug reservoir power source is used for realizing the pumping and infusion of the drug reservoir, the infusion connector with the micro-flow hole and the luer connector is mounted on the drug reservoir, and the power supply and control circuit is mounted in the housing body; the device is characterized by further comprising a hydraulic detection sensor 11, wherein the hydraulic detection sensor 11 is communicated with liquid medicine in the cavity of the medicine storage device and used for detecting the current pressure of the liquid medicine and converting the pressure value into a voltage or current value to be transmitted to the control circuit.
The power source of the medicine storage device comprises an electromagnetic coil 3 and a piston 13 containing a permanent magnet, the electromagnetic coil 3 is tightly wound on a cavity of the medicine storage device, a magnetic field is generated in the electromagnetic coil after the electromagnetic coil is electrified and interacts with the permanent magnet in the piston 13 to push the piston to move, infusion is started and ended by controlling on-off control of current of a coil, and the permanent magnet is fixed on the piston and pushes the piston to advance when acting force from the electromagnetic coil is applied.
For simplifying the calculation, assuming that the inside of the electromagnetic coil is a uniform magnetic field, the magnitude of the acting force of the magnet on the electromagnetic field is as follows: fMagnetic fieldM x V B gradH. Wherein m is magnet mass;
x is the specific magnetization coefficient of the magnet, wherein x is k/p, k is the volume magnetic susceptibility, and p is the density;
b-magnetic field intensity;
v-magnet volume m 3;
gradH-magnetic field gradient.
Wherein, as shown in fig. 3, casing body 8 is a totally closed structure, and its top is just being provided with magnetism to inhale formula and fill interface 7 fast to power and control circuit's position, uses with supporting charger jointly, carries out quick charge for infusion pump inner rechargeable battery, and the one side that is located medicine storage ware cavity 9 still is provided with sensor tie point 10 for connect hydraulic pressure detection sensor and internal control circuit, make internal control circuit can acquire the liquid medicine pressure in the current medicine storage ware in real time.
Wherein, the open-top of medicine storage device cavity has internal thread structure and vertical slot for hold and fixed medicine storage device, power and control circuit comprise charging circuit, MCU and detection circuitry and vibrating motor or bee calling organ.
As shown in fig. 4, a hydraulic pressure detection sensor 11 is installed on one side of the top of the medicine storage device, a contact reed 12 is arranged on one side of the hydraulic pressure detection sensor 11, the contact reed 12 is connected with the hydraulic pressure detection sensor 11, and when the medicine storage device is installed in the shell body, the contact reed 12 is pressed by a sensor connection point on the shell and is in close contact with the sensor connection point, so that an electrical path is established. The contact spring is made of a circular arc-shaped metal sheet with elasticity. The top of the medicine storage device is provided with a luer connector which is used for matching with a medicine pumping connector or an infusion connector.
As shown in fig. 5, the infusion connector 5 contains a microfluidic chip 51 for communicating the drug reservoir and the infusion line, and the microfluidic chip has an inner diameter of less than 5um for controlling the infusion of a small amount of liquid drug. When drawing out medicine, draw liquid connector part 6 and medicine storage device cooperation, outwards pull medicine storage device piston. At this time, negative pressure is formed inside the medicine storage device, and the liquid medicine enters the medicine storage device from the medicine storage bottle, as shown in fig. 9.
As shown in fig. 6-8, when infusion is required, the medicine reservoir is placed in the housing and is tightly matched with the infusion connector, the control circuit is connected with the power supply of the electromagnetic coil, the magnetic field is generated inside the electromagnetic coil and interacts with the magnet in the medicine reservoir to generate thrust on the piston. Assuming that the sectional area of the medicine storage device is SStore upThe force of the electromagnetic coil acting on the permanent magnet is FMagnetic fieldThen the liquid medicine pressure is P according to the liquid pressure principleLiquid for treating urinary tract infection＝FMagnetic field/SStore up. The liquid medicine flows out from the micro-flow holes after being extruded, and the outflow speed V of the liquid medicineLiquid for treating urinary tract infectionThe pressure of the liquid medicine is PLiquid for treating urinary tract infectionCorrelation, the relationship can be expressed using the bernoulli equation:
wherein p is the pressure of a certain point in the fluid, v is the flow velocity of the fluid at the point, ρ is the density of the fluid, g is the gravitational acceleration, h is the height of the point, and C is a constant. For the infusion pump described in this patent, ρ, g, h can be considered as constants, and thus the bernoulli equation can be simplified to C ═ PLiquid for treating urinary tract infection+kVLiquid for treating urinary tract infection 2(k is a coefficient).
Directly measuring the outflow velocity V of the liquid medicineLiquid for treating urinary tract infectionIs difficult, the pressure P of the liquid medicine is measured in real time by a hydraulic detection sensorLiquid for treating urinary tract infectionThen the outflow speed V of the liquid medicine can be indirectly obtained according to the Bernoulli equationLiquid for treating urinary tract infection。
Assuming that the cross-sectional area of the micro-orifice is SMicro-meterAnd the volume of the liquid medicine flowing out in the T time is as follows: l isLiquid for treating urinary tract infection＝SMicroVLiquid (c)And T. Due to the micro-flow hole cross-sectional area SMicro-meterFixed and small inner diameter of the microfluidic hole, and VLiquid for treating urinary tract infectionThe pressure of the liquid medicine is related, namely the current I in the electromagnetic coil, so that micro infusion and precise control can be realized by setting a small value of T and a small value of I.
Compared with the traditional infusion pump, the invention has the following advantages:
1. the infusion precision is high; in the invention, the micro-flow hole is used as a liquid medicine infusion channel, the inner diameter of the micro-flow hole can be as small as 5um, and compared with the traditional infusion pipeline, the liquid medicine flow in a unit time under the same hydraulic pressure can be as small as 2 orders of magnitude.
2. The volume is very small; the invention cancels the traditional mechanical propelling mechanism, thereby greatly reducing the volume of the pump body on the premise of keeping enough dosage and being convenient for a user to wear.
3. Extremely high waterproof and dustproof standards; because the casing of the infusion pump is completely closed and the medicine storage device is pushed by non-contact electromagnetic force, the invention can reach the extremely high waterproof and dustproof standard
4. No noise is generated; because no mechanical propulsion mechanism exists, no noise is generated in the infusion process, and the privacy is good.
5. Very high infusion accuracy; because the micro-fluidic technology and the micro-fluidic chip are utilized, precise infusion and micro-infusion can be realized.
The above description is only an embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that are not thought of through the inventive work should be included in the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope defined by the claims.
Claims (9)
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Cited By (3)
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| CN114146235A (en) * | 2021-11-25 | 2022-03-08 | 秦晶晶 | A multifunctional beauty instrument |
| WO2023122929A1 (en) * | 2021-12-28 | 2023-07-06 | Medtrum Technologies Inc. | Drug infusion device with integrated power supply and the artificial pancreas thereof |
| CN117504055A (en) * | 2023-12-08 | 2024-02-06 | 上海旭润医学科技有限责任公司 | Continuous micro-dosing device and injection method |
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| CN216124958U (en) * | 2021-07-31 | 2022-03-25 | 凯联医疗科技(上海)有限公司 | Infusion pump based on electromagnetic propulsion and micro-flow detection control |
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Application publication date: 20211008 |