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CN113172062A - Washing unit and cell extractor - Google Patents

Washing unit and cell extractor Download PDF

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Publication number
CN113172062A
CN113172062A CN202110611074.9A CN202110611074A CN113172062A CN 113172062 A CN113172062 A CN 113172062A CN 202110611074 A CN202110611074 A CN 202110611074A CN 113172062 A CN113172062 A CN 113172062A
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China
Prior art keywords
cleaning
port
fixing frame
liquid discharge
main body
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Pending
Application number
CN202110611074.9A
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Chinese (zh)
Inventor
宋丹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Qingdao Suzhi Technology Co ltd
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Qingdao Suzhi Technology Co ltd
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Priority to CN202110611074.9A priority Critical patent/CN113172062A/en
Publication of CN113172062A publication Critical patent/CN113172062A/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00Cleaning hollow articles by methods or apparatus specially adapted thereto
    • B08B9/08Cleaning containers, e.g. tanks
    • B08B9/20Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought
    • B08B9/28Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought the apparatus cleaning by splash, spray, or jet application, with or without soaking
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B13/00Accessories or details of general applicability for machines or apparatus for cleaning
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00Cleaning hollow articles by methods or apparatus specially adapted thereto
    • B08B9/08Cleaning containers, e.g. tanks
    • B08B9/20Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought
    • B08B9/28Cleaning containers, e.g. tanks by using apparatus into or on to which containers, e.g. bottles, jars, cans are brought the apparatus cleaning by splash, spray, or jet application, with or without soaking
    • B08B9/34Arrangements of conduits or nozzles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M39/00Means for cleaning the apparatus or avoiding unwanted deposits of microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04Cell isolation or sorting

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  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Mechanical Engineering (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Cleaning By Liquid Or Steam (AREA)

Abstract

The invention provides a cleaning unit and a cell extraction instrument, which relate to the technical field of cell extraction and comprise a driving mechanism, a cleaning fixing frame, a cleaning port and a cleaning pipeline; after the cell sample is extracted, the sample cup is separated from the liquid discharge port, the cleaning fixing frame is driven by the driving mechanism to move relative to the fixing frame of the cell extraction instrument, so that the cleaning port moves to the position of the liquid discharge port of the liquid discharge unit, the cleaning port is detachably connected with the liquid discharge port, and external cleaning liquid is conveyed into the liquid discharge port and an internal channel of the liquid discharge unit through the cleaning port, so that the mechanical corresponding cleaning of the liquid discharge unit is realized, the manual operation is reduced, the influence caused by pollution of the liquid discharge channel of the liquid discharge unit is solved, the operation efficiency is improved, and the inconvenience caused by manual operation is avoided; alleviate the manual work that exists among the prior art and washed the flowing back unit of cell extraction appearance, consumeed the manpower, can't guarantee to drain outlet and inside pipe sanitization, caused the technical problem of pollution easily.

Description

Cleaning unit and cell extraction instrument
Technical Field
The invention relates to the technical field of cell extraction, in particular to a cleaning unit and a cell extraction instrument.
Background
In criminal cases, biological detection materials mixed by human blood and exfoliated epithelial cells, such as cigarette butts, gloves and the like, left by suspects on site in blood stain are often not available. Because of the pollution of the blood of a victim, most of conventional DNA tests are mixed STR (short tandem repeat) typing, even only single STR typing of the victim is obtained due to the dominant amplification of the human blood DNA, so that the difficulty of result interpretation is increased, and strong evidence of referring to a criminal suspect is more likely to be lost.
In the prior art, the cell separation method of the mixed biological test material is mainly studied as follows: the method can directionally capture target cells with high precision, but has the problems of complicated sample pretreatment, expensive equipment consumables, complex operation and difficult popularization; in addition, the microfiltration technology, as a separation technology, plays an important role in the medical fields of leukocyte filtration and separation, separation and capture of circulating tumor cells, and the like, along with the development of materials science and preparation technology, especially the continuous progress of precision processing technology.
Microfiltration technique among the prior art, in cell extraction equipment carries out the cell and draws, can utilize flowing back unit extraction experiment cup in the diluent, until with the complete back of the diluent extraction in the experiment cup, collect the cell sample in the experiment cup again, can utilize the manual work to wash the flowing back unit of cell extraction appearance after collecting the completion, but manual operation consumes the manpower to also can't guarantee to every leakage fluid dram of flowing back unit and inner tube sanitization, cause the pollution easily.
Disclosure of Invention
The invention aims to provide a cleaning unit and a cell extraction instrument, and aims to solve the technical problems that in the prior art, the drainage unit of the cell extraction instrument is washed manually, manpower is consumed, a drainage port and an internal pipeline cannot be cleaned completely, and pollution is easily caused.
The invention provides a cleaning unit, which is applied to washing a drainage unit of a cell extractor and comprises: the cleaning device comprises a driving mechanism, a cleaning fixing frame, a cleaning port and a cleaning pipeline;
the cleaning port is arranged on the cleaning fixing frame, the cleaning port is connected with the cleaning pipeline, the cleaning pipeline is used for conveying external cleaning liquid to the cleaning port, the cleaning fixing frame is connected with the fixing frame of the cell extraction instrument through the driving mechanism, the driving mechanism is used for driving the cleaning fixing frame to move relative to the fixing frame of the cell extraction instrument so that the cleaning port moves to the position of the liquid discharge port of the liquid discharge unit, and the cleaning port is detachably connected with the liquid discharge port.
In a preferred embodiment of the present invention, the cleaning opening is provided with a plurality of cleaning openings, and the plurality of cleaning openings correspond to the plurality of liquid discharge openings of the liquid discharge unit, so that each cleaning opening is connected to one liquid discharge opening;
the number of the cleaning pipelines corresponds to the number of the cleaning ports one to one.
In the preferred embodiment of the invention, the device further comprises a control unit;
the control unit is electrically connected with the driving mechanism, a first motion track and a second motion track are preset in the control unit, the control unit is used for controlling the driving mechanism to drive the cleaning opening to be connected with the liquid discharge opening according to the first motion track, and the control unit is used for controlling the driving mechanism to drive the cleaning opening to be separated from the liquid discharge opening according to the second motion track.
In a preferred embodiment of the invention, a fluid seal is further included;
the fluid sealing piece is sleeved outside the cleaning port and connected with the cleaning port, and the fluid sealing piece is sleeved at the connection position of the cleaning port and the liquid outlet.
In a preferred embodiment of the invention, the cleaning port comprises a male luer connector, and the liquid discharge port comprises a female through-plate luer connector.
In a preferred embodiment of the present invention, the cleaning holder comprises a main body holder and a washing holder;
the number of the washing supports corresponds to the number of the cleaning openings one by one, each washing support is connected with one cleaning opening, the washing supports are arranged at equal intervals along the extending direction of the main body fixing frame, each washing support is respectively and vertically arranged with the main body fixing frame, and the washing supports are respectively connected with the main body fixing frame;
the main body fixing frame is connected with the driving mechanism.
In a preferred embodiment of the present invention, the driving mechanism includes a horizontal moving mechanism and a vertical moving mechanism;
the vertical moving mechanism is in transmission connection with the main body fixing frame and is used for driving the main body fixing frame to reciprocate in the vertical direction so as to connect or separate the cleaning port and the liquid discharge port;
the horizontal moving mechanism is connected with the main body fixing frame through the vertical moving mechanism and is used for driving the main body fixing frame to move in the horizontal direction, so that the cleaning port and the liquid discharge port are arranged just opposite to each other or are arranged in a staggered mode.
In a preferred embodiment of the present invention, the horizontal moving mechanism includes a first driving motor, a fixing base, a first belt pulley, a second belt pulley and a transmission belt;
first belt pulley with the second belt pulley sets up respectively in the both ends of the mount of cell extraction appearance, first belt pulley with pass through between the second belt pulley transmission is connected, one side of fixing base with transmission belt connects, vertical removal removes and is located on the fixing base, first driving motor with first belt pulley transmission is connected, first belt pulley with the second belt pulley is used for passing through transmission belt drives the fixing base is at horizontal direction reciprocating motion, with passing through vertical moving mechanism drives main part fixing frame is at horizontal direction reciprocating motion.
In a preferred embodiment of the present invention, the vertical moving mechanism includes a second driving motor, a lead screw nut and a pushing seat;
the lead screw with the fixing base is connected, lead screw nut cover is located the outside of lead screw, lead screw nut with promote the seat and rotate and connect, lead screw nut passes through promote seat and main part mount butt, second driving motor with lead screw nut transmission is connected, lead screw nut is used for the lead screw is at vertical direction reciprocating motion, in order to pass through promote the seat and drive main part mount reciprocating motion in vertical direction.
The invention provides a cell extraction instrument, which comprises the cleaning unit.
The invention provides a cleaning unit, which is applied to washing a drainage unit of a cell extractor and comprises: the cleaning device comprises a driving mechanism, a cleaning fixing frame, a cleaning port and a cleaning pipeline; the cleaning port is arranged on the cleaning fixing frame, the cleaning port is connected with the cleaning pipeline, the cleaning pipeline is used for conveying external cleaning liquid to the cleaning port, the cleaning fixing frame is connected with the fixing frame of the cell extractor through the driving mechanism, after the cell sample is extracted, the sample cup is separated from the liquid discharge port, the cleaning fixing frame is driven by the driving mechanism to move relative to the fixing frame of the cell extractor so that the cleaning port moves to the position of the liquid discharge port of the liquid discharge unit, the cleaning port is detachably connected with the liquid discharge port, and the external cleaning liquid is conveyed into the liquid discharge port and the internal channel of the liquid discharge unit through the cleaning port, so that the mechanical corresponding cleaning of the liquid discharge unit is realized, the manual operation is reduced, the influence caused by the pollution of the liquid discharge channel of the liquid discharge unit is solved, the operation efficiency is improved, and the inconvenience caused by the manual operation is avoided; alleviate the manual work that exists among the prior art and washed the flowing back unit of cell extraction appearance, consumeed the manpower, can't guarantee to drain outlet and inside pipe sanitization, caused the technical problem of pollution easily.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.
FIG. 1 is a schematic diagram of an overall structure of a side of a cleaning unit having a cleaning opening according to an embodiment of the present invention;
FIG. 2 is a schematic diagram of a partial enlarged structure at a position of a cleaning opening of the cleaning unit provided in the embodiment of FIG. 1;
FIG. 3 is a schematic diagram of the overall structure of one side of the cleaning unit with the driving mechanism according to the embodiment of the present invention;
fig. 4 is a partial enlarged structural schematic diagram of a driving mechanism of the cleaning unit provided in the embodiment of fig. 3.
Icon: 100-cell extractor; 101-a liquid discharge port; 200-a drive mechanism; 201-horizontal moving mechanism; 211-a fixed seat; 221-a first pulley; 231-a transfer belt; 202-vertical movement mechanism; 212-a lead screw; 222-a lead screw nut; 232-a pushing seat; 300-cleaning the fixing frame; 301-main body mount; 302-washing the stent; 400-a cleaning port; 500-cleaning the pipeline; 600-a control unit.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
As shown in fig. 1-4, the present embodiment provides a cleaning unit for washing a drainage unit of a cell extractor 100, comprising: the cleaning device comprises a driving mechanism 200, a cleaning fixing frame 300, a cleaning port 400 and a cleaning pipeline 500; cleaning port 400 sets up on wasing mount 300, cleaning port 400 is connected with washing pipeline 500, washs pipeline 500 and is used for carrying outside washing liquid to cleaning port 400 department, washs mount 300 and is connected with the mount of cell extraction appearance 100 through actuating mechanism 200, actuating mechanism 200 is used for driving to wash mount 300 and removes for the mount of cell extraction appearance 100 to make cleaning port 400 remove to the leakage fluid dram 101 position of drainage cell, cleaning port 400 can dismantle with leakage fluid dram 101 and be connected.
The cleaning unit provided by the embodiment can wash the drainage unit after filtration and extraction, wherein the drainage unit can absorb diluent filtered by the filtering mechanism and impurities in a cell sample, and in order to ensure the cleanness of the drainage unit next time and prevent an uncleaned drainage port 101 from polluting the filtering mechanism installed next time, the drainage unit needs to be cleaned; meanwhile, the connection or separation of the cleaning port 400 and the liquid discharge port 101 can be controlled through the driving mechanism 200, namely, the driving mechanism 200 drives the cleaning fixing frame 300 to move to the position corresponding to the cleaning port 400 and the liquid discharge port 101, under the driving of the driving mechanism 200, the automatic connection or separation of the cleaning port 400 and the liquid discharge port 101 is completed, the whole process does not need manual operation, electromechanical automation operation can be realized, on one hand, the influence caused by pollution of a liquid discharge unit is avoided, on the other hand, the operation efficiency is improved, and inconvenience caused by manual operation is avoided.
It should be noted that, because the filtering mechanism is a disposable structure, the filtering mechanism can be replaced after different cell samples are filtered and extracted each time; the flowing back unit is as cell extraction appearance 100's structure, and the flowing back unit need wash the flowing back unit after accomplishing once to extract, and the cleaning unit that this embodiment provided washes the flowing back unit to can make things convenient for the different diluent of chooseing for use next time, and prevent that the diluent from influencing the use of flowing back unit in the flowing back unit for a long time.
The cleaning unit provided in this embodiment is applied to the washing of the drainage unit of the cell extractor 100, and includes: the cleaning device comprises a driving mechanism 200, a cleaning fixing frame 300, a cleaning port 400 and a cleaning pipeline 500; the cleaning port 400 is arranged on the cleaning fixing frame 300, the cleaning port 400 is connected with the cleaning pipeline 500, the cleaning pipeline 500 is used for conveying external cleaning liquid to the cleaning port 400, the cleaning fixing frame 300 is connected with the fixing frame of the cell extractor 100 through the driving mechanism 200, after the cell sample is extracted, the sample cup is separated from the liquid outlet 101, the driving mechanism 200 drives the cleaning fixing frame 300 to move relative to the fixing frame of the cell extractor 100, the cleaning port 400 is moved to the position of the liquid outlet 101 of the liquid outlet unit, the cleaning port 400 is detachably connected with the liquid outlet 101, and external cleaning liquid is conveyed into the liquid outlet 101 and the internal channel of the liquid outlet unit through the cleaning port 400, so that the mechanical corresponding cleaning of the liquid outlet unit is realized, the manual operation is reduced, the influence caused by the pollution of the liquid outlet channel of the liquid outlet unit is avoided, the operation efficiency is improved, and the inconvenience caused by the manual operation is avoided; alleviate the manual work that exists among the prior art and washed the flowing back unit of cell extraction appearance 100, consumed the manpower, can't guarantee to drain port 101 and inside pipe sanitization, caused the technical problem of pollution easily.
It should be noted that the drainage unit includes a plurality of drainage ports 101, the number of the drainage ports 101 corresponds to the number of the filtering mechanisms one by one, each filtering mechanism is connected to one drainage port 101, and the plurality of drainage ports 101 are arranged on the fixing frame of the cell extraction apparatus 100 at intervals.
In the preferred embodiment of the present invention, the cleaning opening 400 is provided with a plurality of openings 400, and the plurality of openings 400 correspond to the plurality of liquid discharge openings 101 of the liquid discharge unit, so that each cleaning opening 400 is connected to one liquid discharge opening 101; the number of the cleaning lines 500 corresponds one-to-one to the number of the cleaning ports 400.
In this embodiment, the cleaning opening 400 can be set corresponding to the number of the liquid discharge opening 101, so when the driving mechanism 200 utilizes the cleaning fixing frame 300 to drive the plurality of cleaning openings 400 to move, the plurality of cleaning openings 400 can be respectively connected with the plurality of liquid discharge openings 101 in a one-to-one correspondence manner, and then the plurality of liquid discharge openings 101 can be cleaned at one time, so that the design is more reasonable.
In the preferred embodiment of the present invention, the present invention further comprises a control unit 600; the control unit 600 is in electrical signal connection with the driving mechanism 200, a first motion track and a second motion track are preset in the control unit 600, the control unit 600 is used for controlling the driving mechanism 200 to drive the cleaning port 400 to be connected with the liquid discharge port 101 according to the first motion track, and the control unit 600 is used for controlling the driving mechanism 200 to drive the cleaning port 400 to be separated from the liquid discharge port 101 according to the second motion track.
Alternatively, the control unit 600 may be controlled by a computer main body, wherein the control main body of the computer may be various, for example: MCU, CPU, PLC controller, etc., and preferably, the control unit 600 is an MCU. A micro control Unit 600 (MCU), also called a single-chip microcomputer or a single-chip microcomputer, properly reduces the frequency and specification of a central processing Unit, and integrates peripheral interfaces such as a memory, a counter, a USB, an a/D conversion, a UART, a PLC, a DMA, and the like, and even an LCD driving circuit, on a single chip to form a chip-level computer, which performs different combination control for different application occasions.
Wherein, the detecting program can be preset to the control unit 600, finishes the step of filtering and extracting when the filtering mechanism, utilizes the control unit 600 to open the cleaning program, utilizes the control unit 600 to control the driving mechanism 200 to drive and wash the mount 300 and remove to make the washing mouth 400 be connected with the leakage fluid dram 101, realized the automatic washing function of automatic cell extraction appearance 100, whole cleaning process does not need artificial intervention, makes the design more perfect.
In addition, the control unit 600 may further be provided with a touch screen, and the touch screen may be used to select two modes, namely, automatic control and manual control, so that control under different conditions during the cleaning process may be performed.
In a preferred embodiment of the invention, a fluid seal is further included; the fluid sealing element is sleeved outside the cleaning port 400 and connected with the cleaning port 400, and the fluid sealing element is sleeved at the connection position of the cleaning port 400 and the liquid outlet 101.
Optionally, the fluid sealing element may be a rubber sealing ring, and the fluid sealing element can be sleeved at the connection position of the cleaning port 400 and the liquid discharge port 101, so that the connection tightness of the cleaning port 400 and the liquid discharge port 101 can be better ensured by using the fluid sealing element.
In this embodiment, the liquid outlet 101 can be connected to the filter mechanism by a luer fitting in a sealing manner, and in order to enable the cleaning port 400 to be connected to the liquid outlet 101 in a sealing manner, in the preferred embodiment of the present invention, the cleaning port 400 includes a male luer fitting, and the liquid outlet 101 includes a female luer fitting.
In the preferred embodiment of the present invention, the washing holder 300 comprises a main body holder 301 and a washing holder 302; the number of the washing brackets 302 corresponds to the number of the cleaning ports 400 one by one, each washing bracket 302 is connected with one cleaning port 400, the washing brackets 302 are arranged at equal intervals along the extending direction of the main body fixing frame 301, each washing bracket 302 is respectively and vertically arranged with the main body fixing frame 301, and the washing brackets 302 are respectively connected with the main body fixing frame 301; the main body holder 301 is connected to the driving mechanism 200.
In the preferred embodiment of the present invention, the driving mechanism 200 includes a horizontal moving mechanism 201 and a vertical moving mechanism 202; the vertical moving mechanism 202 is in transmission connection with the main body fixing frame 301, and the vertical moving mechanism 202 is used for driving the main body fixing frame 301 to reciprocate in the vertical direction so as to connect or separate the cleaning port 400 with or from the liquid discharge port 101; the horizontal moving mechanism 201 is connected with the main body fixing frame 301 through the vertical moving mechanism 202, and the horizontal moving mechanism 201 is used for driving the main body fixing frame 301 to move in the horizontal direction, so that the cleaning port 400 and the liquid discharge port 101 are arranged in a facing manner or in a staggered manner.
In this embodiment, a plurality of flushing brackets 302 are arranged at equal intervals along the extending direction of the main body fixing frame 301, so that a distance is formed between any two adjacent flushing brackets 302, and the distance between two flushing brackets 302 is set according to two adjacent liquid discharge ports 101; specifically, when the cleaning ports 400 are connected with the liquid discharge ports 101, each cleaning port 400 is connected with the corresponding liquid discharge port 101, and when the cleaning ports 400 are required to be separated from the liquid discharge ports 101, the driving mechanism 200 can utilize the main body fixing frame 301 to complete two actions, that is, the cleaning ports 400 can be separated from the liquid discharge ports 101, and meanwhile, it can be ensured that the connection of the liquid discharge ports 101 and the filtering mechanism is not affected by the flushing bracket 302, wherein the vertical moving mechanism 202 drives the cleaning ports 400 to be separated from the liquid discharge ports 101 in the vertical direction of the cleaning ports 400 and the liquid discharge ports 101, and the horizontal moving mechanism 201 drives the main body fixing frame 301 to move in the horizontal direction, that is, the liquid discharge ports 101 are located at the gap position between any two adjacent flushing brackets 302, so that the liquid discharge ports 101 can be connected with the filtering mechanism in the vertical direction; on the contrary, when the cleaning opening 400 needs to be connected with the liquid discharge opening 101, only the horizontal moving mechanism 201 needs to be opened first and then the vertical moving mechanism 202 needs to be opened in the opposite direction, so that the cleaning opening 400 is connected with the liquid discharge opening 101, which is not described herein again.
In the preferred embodiment of the present invention, the horizontal moving mechanism 201 includes a first driving motor, a fixing base 211, a first pulley 221, a second pulley, and a transmission belt 231; first belt pulley 221 and second belt pulley set up respectively in the both ends of the mount of cell extraction appearance 100, be connected through transmission belt 231 transmission between first belt pulley 221 and the second belt pulley, one side and the transmission belt 231 of fixing base 211 are connected, vertical movement removes and is located the fixing base 211, a driving motor is connected with first belt pulley 221 transmission, first belt pulley 221 and second belt pulley are used for driving fixing base 211 at the reciprocating motion of horizontal direction through transmission belt 231, in order to drive main part mount 301 at the reciprocating motion of horizontal direction through vertical movement mechanism 202.
Wherein, the direction of the transmission belt 231 is the same as the direction of the arrangement of the plurality of liquid discharge ports 101, the operation driving of the transmission belt 231 is realized by the first belt pulley 221 and the second belt pulley, meanwhile, the first driving motor can realize the reciprocating motion of the transmission belt 231 in the horizontal direction by positive rotation or negative rotation, further, the transmission belt 231 is connected with the fixed seat 211, when the transmission belt 231 operates, the vertical moving mechanism 202 can horizontally move along with the transmission belt 231 through the fixed seat 211 at this time, that is, the transmission belt 231 drives the main body fixing frame 301 to reciprocate in the horizontal direction through the fixed seat 211 and the vertical moving mechanism 202, and the moving path of the main body fixing frame 301 in the horizontal direction is based on the path program preset by the control unit 600.
In the preferred embodiment of the present invention, the vertical moving mechanism 202 includes a second driving motor, a lead screw 212, a lead screw nut 222 and a pushing seat 232; the lead screw 212 is connected with the fixing seat 211, the lead screw nut 222 is sleeved outside the lead screw 212, the lead screw nut 222 is rotatably connected with the pushing seat 232, the lead screw nut 222 is abutted to the main body fixing frame 301 through the pushing seat 232, the second driving motor is in transmission connection with the lead screw nut 222, and the lead screw nut 222 is used for reciprocating in the vertical direction relative to the lead screw 212 so as to drive the main body fixing frame 301 to reciprocate in the vertical direction through the pushing seat 232.
Optionally, the lead screw 212 is fixed on the fixing base 211, the lead screw nut 222 can reciprocate in the vertical direction relative to the lead screw 212, the lead screw nut 222 is abutted to the flushing fixing frame, the lead screw nut 222 can reciprocate in the vertical direction relative to the lead screw 212 under the driving of the second driving motor, the reciprocating motion of the lead screw nut 222 in the vertical direction is realized by the over-positive rotation or the counter-positive rotation of the second driving motor, and then the lead screw nut 222 pushes the main body fixing frame 301 to reciprocate in the vertical direction by using the pushing bearing.
The cell extractor 100 provided by this embodiment includes the cleaning unit; since the technical effect of the cell extractor 100 provided in this embodiment is the same as that of the cleaning unit provided in the above embodiment, the detailed description thereof is omitted here.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.

Claims (10)

1.一种清洗单元,应用于细胞提取仪的排液单元的冲洗,其特征在于,包括:驱动机构、清洗固定架、清洗口和清洗管路;1. A cleaning unit, applied to the flushing of the liquid discharge unit of a cell extractor, characterized in that, comprising: a drive mechanism, a cleaning fixture, a cleaning port and a cleaning pipeline; 所述清洗口设置于所述清洗固定架上,所述清洗口与所述清洗管路连接,所述清洗管路用于将外部清洗液输送至所述清洗口处,所述清洗固定架通过所述驱动机构与所述细胞提取仪的固定架连接,所述驱动机构用于带动所述清洗固定架相对于所述细胞提取仪的固定架移动,以使所述清洗口移动至所述排液单元的排液口位置,所述清洗口与所述排液口可拆卸连接。The cleaning port is arranged on the cleaning fixture, the cleaning port is connected with the cleaning pipeline, and the cleaning pipeline is used to transport external cleaning liquid to the cleaning hole, and the cleaning fixture passes through The driving mechanism is connected with the fixing frame of the cell extractor, and the driving mechanism is used to drive the cleaning fixing frame to move relative to the fixing frame of the cell extracting apparatus, so as to move the cleaning port to the row The position of the liquid discharge port of the liquid unit, and the cleaning port is detachably connected to the liquid discharge port. 2.根据权利要求1所述的清洗单元,其特征在于,所述清洗口设置有多个,多个所述清洗口对应所述排液单元的多个所述排液口,以使每个所述清洗口分别与一个所述排液口连接;2 . The cleaning unit according to claim 1 , wherein a plurality of the cleaning ports are provided, and the plurality of the cleaning ports correspond to the plurality of the liquid drain ports of the liquid drain unit, so that each The cleaning ports are respectively connected with one of the drain ports; 所述清洗管路的数量与所述清洗口的数量一一对应。The number of the cleaning pipelines corresponds to the number of the cleaning ports one-to-one. 3.根据权利要求2所述的清洗单元,其特征在于,还包括控制单元;3. The cleaning unit according to claim 2, further comprising a control unit; 所述控制单元与所述驱动机构电信号连接,所述控制单元预设有第一运动轨迹和第二运动轨迹,所述控制单元用于根据第一运动轨迹控制所述驱动机构带动所述清洗口与所述排液口连接,所述控制单元用于根据第二运动轨迹控制所述驱动机构带动所述清洗口与所述排液口分离。The control unit is electrically connected to the driving mechanism, the control unit is preset with a first motion track and a second motion track, and the control unit is used to control the drive mechanism to drive the cleaning according to the first motion track The port is connected to the liquid discharge port, and the control unit is configured to control the driving mechanism to drive the cleaning port to separate from the liquid discharge port according to the second movement track. 4.根据权利要求3所述的清洗单元,其特征在于,还包括流体密封件;4. The cleaning unit of claim 3, further comprising a fluid seal; 所述流体密封件套设于所述清洗口的外部,所述流体密封件与所述清洗口连接,所述流体密封件用于套设于所述清洗口和所述排液口的连接处。The fluid seal is sleeved on the outside of the cleaning port, the fluid seal is connected to the cleaning port, and the fluid seal is used to sleeve at the connection between the cleaning port and the drain port . 5.根据权利要求4所述的清洗单元,其特征在于,所述清洗口包括鲁尔公接头,所述排液口包括穿板鲁尔母接头。5. The cleaning unit of claim 4, wherein the cleaning port includes a male Luer connector, and the drain port includes a female Luer connector through the plate. 6.根据权利要求2-5任一项所述的清洗单元,其特征在于,所述清洗固定架包括主体固定架和冲洗支架;6. The cleaning unit according to any one of claims 2-5, wherein the cleaning fixing frame comprises a main body fixing frame and a flushing support; 所述冲洗支架的数量与所述清洗口的数量一一对应,每个所述冲洗支架与一个所述清洗口连接,多个所述冲洗支架沿着所述主体固定架的延伸方向呈等间距布置,且每个所述冲洗支架分别与所述主体固定架呈垂直设置,多个所述冲洗支架分别与所述主体固定架连接;The number of the flushing brackets corresponds to the number of the cleaning ports, each of the flushing brackets is connected to one of the cleaning ports, and a plurality of the flushing brackets are equally spaced along the extending direction of the main body fixing frame arranged, and each of the flushing brackets is respectively arranged vertically with the main body fixing frame, and a plurality of the flushing brackets are respectively connected with the main body fixing frame; 所述主体固定架与所述驱动机构连接。The main body fixing frame is connected with the driving mechanism. 7.根据权利要求6所述的清洗单元,其特征在于,所述驱动机构包括水平移动机构和竖直移动机构;7. The cleaning unit according to claim 6, wherein the driving mechanism comprises a horizontal moving mechanism and a vertical moving mechanism; 所述竖直移动机构与所述主体固定架传动连接,所述竖直移动机构用于带动所述主体固定架在竖直方向往复移动,以使所述清洗口与所述排液口连接或分离;The vertical moving mechanism is connected with the main body fixing frame by transmission, and the vertical moving mechanism is used to drive the main body fixing frame to reciprocate in the vertical direction, so as to connect the cleaning port with the liquid discharge port or separate; 所述水平移动机构通过所述竖直移动机构与所述主体固定架连接,所述水平移动机构用于带动所述主体固定架在水平方向移动,以使所述清洗口与所述排液口正对布置或错位布置。The horizontal moving mechanism is connected with the main body fixing frame through the vertical moving mechanism, and the horizontal moving mechanism is used to drive the main body fixing frame to move in the horizontal direction, so that the cleaning port and the liquid discharge port are connected. Straight or misaligned. 8.根据权利要求7所述的清洗单元,其特征在于,所述水平移动机构包括第一驱动电机、固定座、第一皮带轮、第二皮带轮和传输皮带;8. The cleaning unit according to claim 7, wherein the horizontal moving mechanism comprises a first drive motor, a fixed seat, a first pulley, a second pulley and a transmission belt; 所述第一皮带轮和所述第二皮带轮分别设置于细胞提取仪的固定架的两端,所述第一皮带轮和所述第二皮带轮之间通过所述传输皮带传动连接,所述固定座的一侧与所述传输皮带连接,所述竖直移动移动位于所述固定座上,所述第一驱动电机与所述第一皮带轮传动连接,所述第一皮带轮和所述第二皮带轮用于通过所述传输皮带带动所述固定座在水平方向往复移动,以通过所述竖直移动机构带动所述主体固定架在水平方向往复移动。The first pulley and the second pulley are respectively arranged at both ends of the fixing frame of the cell extractor, and the first pulley and the second pulley are connected by the transmission belt. One side is connected with the transmission belt, the vertical movement is located on the fixed seat, the first drive motor is in driving connection with the first pulley, and the first pulley and the second pulley are used for The fixed seat is driven to reciprocate in the horizontal direction by the transmission belt, so as to drive the main body fixed frame to reciprocate in the horizontal direction through the vertical movement mechanism. 9.根据权利要求8所述的清洗单元,其特征在于,所述竖直移动机构包括第二驱动电机、丝杠、丝杠螺母和推动座;9. The cleaning unit according to claim 8, wherein the vertical moving mechanism comprises a second driving motor, a lead screw, a lead screw nut and a push seat; 所述丝杠与所述固定座连接,所述丝杠螺母套设于所述丝杠的外部,所述丝杠螺母与所述推动座转动连接,所述丝杠螺母通过所述推动座与主体固定架抵接,所述第二驱动电机与所述丝杠螺母传动连接,所述丝杠螺母用于相对于所述丝杠在竖直方向往复移动,以通过所述推动座带动所述主体固定架在竖直方向往复移动。The lead screw is connected with the fixed seat, the lead screw nut is sleeved on the outside of the lead screw, the lead screw nut is rotatably connected with the push seat, and the lead screw nut is connected to the push seat through the push seat. The main body fixing frame is abutted, the second drive motor is drivingly connected with the lead screw nut, and the lead screw nut is used to reciprocate in the vertical direction relative to the lead screw, so as to drive the drive seat through the push seat The main body fixing frame reciprocates in the vertical direction. 10.一种细胞提取仪,其特征在于,包括如权利要求1-9任一项所述的清洗单元。10. A cell extractor, characterized by comprising the cleaning unit according to any one of claims 1-9.
CN202110611074.9A 2021-06-01 2021-06-01 Washing unit and cell extractor Pending CN113172062A (en)

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Application publication date: 20210727