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CN112136819B - Sterilization composition containing fenpicoxamid and penflufen - Google Patents

Sterilization composition containing fenpicoxamid and penflufen Download PDF

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Publication number
CN112136819B
CN112136819B CN201910557831.1A CN201910557831A CN112136819B CN 112136819 B CN112136819 B CN 112136819B CN 201910557831 A CN201910557831 A CN 201910557831A CN 112136819 B CN112136819 B CN 112136819B
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penflufen
active ingredient
composition
use according
fennocoxamid
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CN112136819A (en
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葛家成
杨志鹏
司国栋
张永芳
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Hailir Pesticides and Chemicals Group Co Ltd
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Hailir Pesticides and Chemicals Group Co Ltd
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention relates to a bactericidal composition containing fenpicloram and penflufen, which contains active ingredients fenpicloram and penflufen, wherein the weight ratio of the active ingredients fenpicloram to penflufen is 1:80-80:1. The composition has higher activity on various diseases of various crops, and has the characteristics of synergism, small dosage and the like.

Description

Sterilization composition containing fenpicoxamid and penflufen
Technical Field
The invention belongs to the technical field of pesticides, and relates to an application of a bactericidal composition containing fenpicloram and penflufen in crop diseases.
Technical Field
CAS accession number of Fenpicoxamid: 517875-34-2, molecular formula: c (C) 31 H 38 N 2 O 11 The method comprises the steps of carrying out a first treatment on the surface of the Chemical name: (3S, 6S,7R, 8R) -8-benzyl-3- {3- [ (isobutyryloxy) methoxy group]-4-methoxypyridine-2-carboxamido } -6-methyl-4, 9-dioxo-1, 5-dioxo-non-7-yl isobutyrate having the chemical structural formula:
the Fenpicoxamid is derived from a natural compound UK-2A through fermentation, and has good toxicological characteristics; as the 1 st member of the novel pyridine amide type cereal germicides; bactericidal activity is exerted by inhibiting mitochondrial respiration at the ubiquinone (i.e. coenzyme Q) binding site of the fungal complex iii Qi. Fenpicoxamid has no cross-resistance to existing cereal bactericides.
CAS accession number of Penflufen (Penflufen): 94793-67-8, molecular formula C 18 H 24 FN 3 O, chemical name is 2' - [ (RS) -1, 3-dimethylbutyl]-5-fluoro-1, 3-dimethylpyrazole-4-carboxylic acid anilide having the following chemical formula:
penflufen is a succinate dehydrogenase inhibitor and mainly acts on a respiratory chain electron transfer complex II to block energy metabolism; can prevent and treat seed-borne and soil-borne basidiomycete and ascomycete diseases. The treated seeds can absorb the penflufen in the germination process, and are transmitted to other parts of the plant body through xylem to play a role in protecting crops.
In the actual process of agricultural production, the most easily generated problem of disease control is the generation of pathogen resistance, and the mixing of different varieties of components is a common method for controlling the generation of pathogen resistance. The active ingredients with different action mechanisms are mixed and judged whether to have synergistic, additive or antagonistic action according to the actual application effect. In most cases, the pesticide mixing effect is additive effect, the actual synergistic mixing is little, and especially the obvious synergistic mixing is less. The inventor researches show that the fenpicloram and the penflufen are mixed, so that the fenpicloram and the penflufen have good synergistic effect in a certain range, and related mixing of the fenpicloram and the penflufen is not reported at present.
Disclosure of Invention
The invention aims to provide a bactericidal composition containing fenpiclamid and penflufen, which has the advantages of synergistic effect, low use cost and good prevention effect.
The technical scheme of the invention is as follows:
a bactericidal composition containing fenpicloram and penflufen comprises an active ingredient fenpicloram and penflufen;
further, the weight ratio of the active ingredient fenpiclamid to the active ingredient penflufen is 1:80-80:1;
further, the weight ratio of the active ingredient fenpiclamid to the active ingredient penflufen is 1:50-50:1;
further, the weight ratio of the active ingredient fenpiclamid to the active ingredient penflufen is 1:20-20:1;
further, the weight ratio of the active ingredient fenpiclamid to the active ingredient penflufen is 1:5-10:1;
further, the weight ratio of the active ingredient fenpiclamid to the active ingredient penflufen is 1:3-3:1;
further, the weight ratio of the active ingredient fenpiclamid to the active ingredient penflufen is 1:2.
The bactericide composition preparation can be prepared into a dosage form allowed in the pesticide field;
further, the composition comprises an active ingredient and an auxiliary ingredient of a pesticide preparation;
further, the auxiliary components of the pesticide preparation comprise a carrier and an auxiliary agent;
further, the carrier is any one, two or three of water, a solvent or a filler, and the water is preferably deionized water;
further, the solvent is selected from one or more of N, N-dimethylformamide, cyclohexanone, toluene, xylene, dimethyl sulfoxide, methanol, ethanol, trimethylcyclohexanone, N-octyl pyrrolidone, ethanolamine, triethanolamine, isopropylamine, N-methylpyrrolidone, propanol, butanol, ethylene glycol, diethylene glycol, ethylene glycol methyl ether, butyl ether, ethanolamine, isopropylamine, ethyl acetate or acetonitrile;
further, the filler is selected from one or a mixture of more of kaolin, diatomite, bentonite, attapulgite, white carbon black, starch or light calcium carbonate;
further, the auxiliary agent at least comprises a surfactant, and other functional auxiliary agents such as an antifreezing agent, a thickening agent, a stabilizing agent, a disintegrating agent, a defoaming agent and the like can be added according to different use occasions and requirements;
further, the surfactant is selected from one or more of an emulsifier, a dispersant, a wetting agent or a penetrating agent;
further, the other functional auxiliary agents are selected from one or more of antifreezing agents, thickening agents, stabilizing agents, disintegrating agents or defoaming agents;
further, the emulsifier is selected from one or more of nonylphenol 500# (calcium alkylbenzenesulfonate), OP series phosphate (nonylphenol polyoxyethylene ether phosphate), 600# phosphate (phenylphenol polyoxyethylene ether phosphate), styrene polyoxyethylene ether ammonium sulfate, magnesium alkyldiphenyl ether disulfonate, triethanolamine salt, nonylphenol 400# (benzyl dimethyl phenol polyoxyethylene ether), nonylphenol 700# (alkylphenol formaldehyde resin polyoxyethylene ether), nonylphenol 36# (phenethyl phenol formaldehyde resin polyoxyethylene ether), nonylphenol 1600# (phenethyl phenol polyoxyethylene polypropylene ether), ethylene oxide-propylene oxide block copolymer, OP series (nonylphenol polyoxyethylene ether), BY series (castor oil polyoxyethylene ether), nonylphenol 33# (alkylaryl polyoxyethylene polyoxypropylene ether), span series (sorbitan monostearate) polyoxyethylene ether), tween series (sorbitan polyoxyethylene ether) or AEO series (fatty alcohol polyoxyethylene ether);
further, the dispersing agent is selected from one or more of polycarboxylate, lignosulfonate, alkylphenol ethoxylate formaldehyde condensate sulfate, calcium alkylbenzenesulfonate, naphthalene sulfonate formaldehyde condensate sodium salt, alkylphenol ethoxylate, fatty amine ethoxylate, fatty acid ethoxylate or glycerin fatty acid ester ethoxylate;
further, the wetting agent is selected from one or a mixture of more of sodium dodecyl sulfate, sodium dodecyl benzene sulfonate, nekal BX, wetting penetrating agent F, chinese honeylocust fruit powder, silkworm excrement or soapberry powder;
further, the penetrating agent is selected from one or a mixture of more of penetrating agent JFC (fatty alcohol polyoxyethylene ether), penetrating agent T (diisooctyl maleate sulfonate), azone or organic silicon;
further, the antifreezing agent is selected from a mixture consisting of one or more of ethylene glycol, propylene glycol, glycerol or urea;
further, the thickener is selected from one or more of xanthan gum, polyvinyl alcohol, bentonite, carboxymethyl cellulose or magnesium aluminum silicate;
further, the stabilizer is selected from one or a mixture of more of epoxidized soybean oil, epichlorohydrin, BHT, ethyl acetate and triphenyl phosphate;
further, the disintegrating agent is selected from one or a mixture of more of bentonite, urea, ammonium sulfate, aluminum chloride, low-substituted hydroxypropyl cellulose, lactose, citric acid, succinic acid or sodium bicarbonate;
further, the defoamer is selected from one or a mixture of more of silicone oil, silicone compounds, C10-C20 saturated fatty acid compounds or C8-C10 fatty alcohol compounds;
all of the above materials are commercially available.
The sum of the content of the active ingredient fenpicloram and the content of the active ingredient penflufen in the bactericidal composition is 1-90% of the total weight of the composition;
further, the sum of the content of the active ingredient fenpicloram and the content of the active ingredient penflufen in the bactericidal composition is 10-50% of the total weight of the bactericidal composition.
The bactericidal composition of the invention can be prepared into a preparation formulation acceptable in pesticides according to a method known to a person skilled in the art, and comprises a solid preparation, a liquid preparation, a seed treatment preparation and other preparations;
further, the solid preparation is powder, dispersible tablets, granules, soluble powder, soluble granules, soluble tablets, emulsion powder, emulsion granules, water dispersible granules, wettable powder, microcapsule granules, powder, large granules and water dispersible tablets;
further, the liquid preparation is microcapsule suspending agent, dispersible agent, emulsifiable concentrate, emulsion granule, oil emulsion, emulsion powder, aqueous emulsion, microemulsion, dispersible oil suspending agent, oil dispersion powder, suspending agent, soluble liquid and ultra-low volume liquid;
further, the seed treatment preparation is suspension seed coating agent, seed treatment dry powder, seed treatment dispersible powder, seed treatment suspending agent and seed treatment liquid;
further, the other preparations are baits, concentrated baits, gas preparations, aerosols and smoke agents;
furthermore, the preparation formulation is preferably wettable powder, water dispersible granules and suspending agents.
Further, the composition is prepared into wettable powder, and the components and the content of the wettable powder are preferably as follows: 0.1 to 80 percent of fenpiclamid, 0.1 to 80 percent of penflufen, 2 to 10 percent of dispersing agent, 2 to 10 percent of wetting agent and the balance of filler;
further, the composition is prepared into water dispersible granules, and the components and the content of the water dispersible granules are preferably as follows: 0.1 to 80 percent of fenpicloram, 0.1 to 80 percent of penflufen, 3 to 12 percent of dispersing agent, 1 to 8 percent of wetting agent, 1 to 10 percent of disintegrating agent and the balance of filler.
Further, the composition is prepared into a suspending agent, and the suspending agent comprises the following components in percentage by weight: 0.1 to 80 percent of fenpicloram, 0.1 to 80 percent of penflufen, 2 to 10 percent of dispersing agent, 2 to 10 percent of wetting agent, 0.01 to 2 percent of defoaming agent, 0 to 2 percent of thickening agent, 0 to 8 percent of antifreeze agent and the balance of deionized water;
the invention has the following advantages: 1) The synergy is obvious, the simple superposition of the activities of the components is not realized, and the efficacy is greatly improved; 2) The prevention and treatment effect is outstanding, the duration is long, and the resistance risk is small; 3) The field dosage of the active ingredients is reduced, the production and use cost is reduced, and the pesticide residue and the environmental pollution are reduced; 4) The composition comprises active ingredients with different action mechanisms, and the action sites are increased, so that the generation of drug resistance of diseases is overcome and delayed.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more concise, the present invention will be described in the following specific examples, but the present invention is by no means limited to these examples. The following examples are only preferred embodiments of the present invention, which can be used to describe the present invention, and should not be construed as limiting the scope of the invention. It should be noted that any modifications, equivalent substitutions and improvements made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Case of preparation
EXAMPLE 1:20% fennocoxamid-penflufen wettable powder (1:3)
The formula comprises the following components: 5% fennocoxamid, 15% penflufen, 6% sodium lignin sulfonate, 4% sodium dodecyl benzene sulfonate and kaolin are added for the balance;
the preparation method comprises the following steps: the active ingredients, the dispersing agent, the wetting agent and the filler are uniformly mixed, crushed by an airflow crusher and then uniformly mixed for the second time, and the wettable powder can be prepared.
Example 2:15% fennocoxamid-penflufen wettable powder (1:2)
The formula comprises the following components: 5% fennocoxamid, 10% penflufen, 3% naphthalene sulfonic acid formaldehyde condensate sodium salt, 3% wetting penetrating agent F and white carbon black are added for the balance;
the preparation method comprises the following steps: as in example 1.
Example 3:10% fennocoxamid-penflufen wettable powder (1:1)
The formula comprises the following components: 5% fennocoxamid, 5% penflufen, 5% alkylphenol polyoxyethylene succinate sulfonic acid, 4% sodium dodecyl benzene sulfonate and light carbonic acid are added for the rest;
the preparation method comprises the following steps: as in example 1.
Example 4:40% fennocoxamid-penflufen wettable powder (3:5)
The formula comprises the following components: 15% fennocoxamid, 25% penflufen, 4% dialkyl naphthalene sulfonate, 6% sodium lauryl sulfate and bentonite, and the balance being made up;
the preparation method comprises the following steps: as in example 1.
Example 5:30% fennocoxamid-penflufen wettable powder (1:5)
The formula comprises the following components: 5% fennocoxamid, 25% penflufen, 6% naphthalene sulfonic acid formaldehyde condensate sodium salt, 4% sodium dodecyl benzene sulfonate and kaolin are added for the rest;
the preparation method comprises the following steps: as in example 1.
Example 6:30% fennocoxamid-penflufen water dispersible granule (1:1)
The formula comprises the following components: 15% fennocoxamid, 15% penflufen, 6% fatty alcohol polyoxyethylene ether, 2% sodium dodecyl benzene sulfonate, 2% magnesium aluminum silicate, 0.5% sodium bicarbonate and white carbon black are used for the balance;
the preparation method comprises the following steps: the water dispersible granule disclosed by the invention is prepared by carrying out jet milling on an active ingredient, a dispersing agent, a wetting agent, a binder, a disintegrating agent and a filler to obtain the required particle size, and then delivering the particle size into a fluidized bed granulating dryer for granulating and drying.
Example 7:30% fennocoxamid-penflufen water dispersible granule (1:2)
The formula comprises the following components: 10% fennocoxamid, 20% penflufen, 3% octyl phenol polyoxyethylene ether sulfate, 2% fenvalerate BX, 2% hydroxyethyl cellulose, 3% urea and white carbon black are used for the balance;
the preparation method comprises the following steps: same as in example 6.
Example 8:10% fennocoxamid-penflufen water dispersible granule (1:4)
The formula comprises the following components: 2% fennocoxamid, 8% penflufen, 4% fatty alcohol polyoxyethylene ether, 5% sodium dodecyl sulfate, 2% magnesium aluminum silicate, 2% aluminum chloride and clay are added for the rest;
the preparation method comprises the following steps: same as in example 6.
Example 9:15% fennocoxamid-penflufen water dispersible granule (1:2)
The formula comprises the following components: 5% fennocoxamid, 10% penflufen, 4% fatty alcohol polyoxyethylene ether, 5% sodium dodecyl sulfate, 2% hydroxyethyl cellulose, 3% urea and white carbon black are added for the balance;
the preparation method comprises the following steps: same as in example 6.
Example 10:25% fennocoxamid-penflufen water dispersible granule (2:3)
The formula comprises the following components: 10% fennocoxamid, 15% penflufen, 4% fatty alcohol polyoxyethylene ether, 5% sodium dodecyl sulfate, 2% hydroxyethyl cellulose, 2% magnesium aluminum silicate, 2% aluminum chloride and clay, and the balance being made up;
the preparation method comprises the following steps: same as in example 6.
Example 11:25% fennocoxamid penflufen suspension (2:3)
The formula comprises the following components: 10% fennocoxamid, 15% penflufen, 2% sodium octyl phenol polyoxyethylene ether sulfate, 3% spina gleditsiae powder, 2% propylene glycol, 2% silicone oil and deionized water are used for the balance;
the preparation method comprises the following steps: the suspending agent is prepared by uniformly shearing and mixing the auxiliary agents such as dispersing agent, wetting agent, defoamer, thickener, anti-freezing agent and the like at high speed, adding the active ingredients, complementing the balance with deionized water, and grinding in a ball mill for 2-3 hours to ensure that the particle size of particles is below 5 um.
Example 12:15% fennocoxamid-penflufen suspension (2:1)
The formula comprises the following components: 10% fennocoxamid, 5% penflufen, 3% ester polyoxyethylene ether, 3% sodium dodecyl sulfate, 2% triethylene glycol, 2% organosilicon, 3% magnesium aluminum silicate and deionized water are added to the balance;
the preparation method comprises the following steps: same as in example 11.
Example 13:30% fennocoxamid-penflufen suspension (1:2)
The formula comprises the following components: 10% fennocoxamid, 20% penflufen, 2% sodium lignin sulfonate, 3% sodium lauryl sulfate, 2% triethylene glycol, 4% organic silicon, 3% gelatin and deionized water are added to the balance;
the preparation method comprises the following steps: same as in example 11.
Example 14:20% fennocoxamid-penflufen suspension (1:1)
The formula comprises the following components: 10% fennocoxamid, 10% penflufen, 3% ester polyoxyethylene ether, 3% sodium dodecyl sulfate, 2% triethylene glycol, 4% organosilicon, 3% magnesium aluminum silicate and deionized water are added to the balance;
the preparation method comprises the following steps: same as in example 11.
Example 15:40% fennocoxamid penflufen suspension (2:3)
The formula comprises the following components: 16% fennocoxamid, 24% penflufen, 3% ester polyoxyethylene ether, 3% sodium dodecyl sulfate, 2% triethylene glycol, 4% organosilicon, 3% gelatin and deionized water are added to the balance;
the preparation method comprises the following steps: same as in example 11.
Indoor active cases
Example 16: indoor activity of fenpicloram and penflufen against wheat powdery mildew.
The test is based on: ny/T1156.4-2006 section 4 of pesticide, section 4 of biological assay test criteria in pesticide: experimental potting method for preventing and curing wheat powdery mildew.
Test target: powdery mildew (Erysiphe graminis).
Test instrument: electronic balance (sensing 0.1 mg), spray device, microscope, conical flask, pipette, cylinder, hemacytometer, counter, etc.
Preparing a test material: and (3) selecting a disease-sensitive wheat pot culture, and growing seedlings to a 2-3 leaf stage.
Test agent: 94% fennocoxamid technical and 97% penflufen technical.
And (3) preparation of a medicament: the original medicinal solvent dimethylformamide is dissolved, diluted by 0.1% Tween 80 aqueous solution, and 5 series of mass concentrations are set.
And (3) medicament treatment: and uniformly shaking out fresh spores of powdery mildew generated within 24 hours on the diseased wheat leaves, and inoculating the fresh spores on 2-3 leaf stage potted wheat seedlings to be treated. Every treatment of 3 pots, 10 wheat plants per pot. Drug spraying was performed 24 hours after inoculation, 4 replicates per treatment, and a blank control was set.
Data investigation: grading investigation is carried out according to the disease condition of the blank control. The following classification method is adopted:
level 0: no disease;
stage 1: the area of the disease spots accounts for less than 5% of the area of the whole leaf;
3 stages: the area of the disease spots accounts for 6% -15% of the area of the whole leaf;
5 stages: the area of the disease spots accounts for 16% -25% of the area of the whole leaf;
7 stages: the area of the disease spots accounts for 26% -50% of the area of the whole leaf;
stage 9: the area of the disease spots accounts for more than 50% of the area of the whole leaf.
Data statistical analysis: and calculating the disease index and the prevention and treatment effect of each treatment according to the investigation data. The calculation formula is as follows:
disease index = Σ (number of diseased leaves at each stage×number of relative stages)/(total number of leaves×9) ×100
Control effect (%) = (control disease index-treatment area disease index)/control disease index×100
Grand cloud Pei method: the synergy of the mixed medicines is evaluated according to the co-toxicity coefficient (CTC), namely CTC is equal to or less than 80 and is antagonistic, CTC is additive between 80 and 120, and CTC is synergistic more than or equal to 120. The co-toxicity coefficient calculation formula is as follows:
measured toxicity index of the cocktail = EC of standard agents 50 EC of the mixture 50 ×100
Theoretical toxicity index of the mixture = toxicity index of agent a x percent of agent a in the mixture + toxicity index of agent B x percent of agent B in the mixture
Co-toxicity coefficient (CTC) =measured toxicity index of the blend/theoretical toxicity index of the blend x 100
Test results:
TABLE 1 Combined toxicity results of fennocoxamid and penflufen in combination against wheat powdery mildew
The test results are shown (see Table 1): when the ratio of fenlocoxamid to penflufen is 1:50-50:1, the co-toxicity coefficients are all larger than 80, which indicates that the fenlocoxamid and penflufen are mixed within the range of 1:50-50:1 to show additive or synergistic effect; the ratio of fennocoxamid to penflufen is 1:20-20:1, and the co-toxicity coefficients are all greater than 120, which shows synergistic effect; the ratio of fennocoxamid to penflufen is 1:5-10:1, the synergistic effect is more remarkable, and the co-toxicity coefficients are all more than 160; the ratio of fennocoxamid to penflufen is 1:3-3:1, the synergistic effect is more prominent, and the co-toxicity coefficient is more than 200. The inventor experiments find that the preferable ratio of the fenrocoxamid to the penflufen is 1:20, 1:10, 1:5, 1:3, 1:2, 1:1, 2:1, 3:1, 5:1, 10:1 and 20:1; wherein the synergistic effect is most prominent when the ratio of fennocoxamid to penflufen is 1:2, and the co-toxicity coefficient is 297.76.
Field efficacy test
Example 17: and (3) performing field test on preventing and treating rice sheath blight by compounding fenrocoxamid and penflufen.
The test is based on: GB/T17980.20-2000 "pesticide field efficacy test criterion (one)" Bactericide for controlling rice sheath blight disease ".
Test target: rice sheath blight disease (Rhizoctonia solani); rice variety "Guangliangyou 15".
Environmental conditions: the test field is arranged in a village coated in the Huangpi county, the test field is sandy loam, rich water and the like, the previous stubble is rice, the winter is free, the management is consistent, irrigation conditions are provided, the rice sheath blight and the like happen in a biased manner, the management conditions of each district are good, the rice growth vigor is good, and other pesticides are not applied before and after the test.
Test agent: 20% of fennocoxamid-penflufen wettable powder, 30% of fennocoxamid-penflufen water dispersible granule and 20% of fennocoxamid-penflufen suspending agent.
Control agent: 10% of fennocoxamid suspending agent, 20% of penflufen water dispersible granule and a clear water control.
Cell area and repetition: the cell area is 20 square meters, and each treatment is repeated 4 times.
The application method comprises the following steps: the chemical liquid amount of 750 liters per hectare is converted into the chemical dosage of each district, and the rice cluster base is sprayed as much as possible on the premise of ensuring the penetration during chemical spraying, so that the affected part is fully subjected to chemical. The administration is started at 7 months and 8 days in the initial stage of the rice sheath blight, and a second administration is performed 2 times after 7 days (7 months and 15 days) at intervals.
Investigation and recording: disease number was investigated before the drug (day 7 month 8), mid-term results were investigated 7 days after the first drug (day 7 month 15), and final results were investigated 14 days after the 2 nd drug (day 7 month 29).
Samples were taken at 5 points diagonally per cell, 5 clusters were investigated per point, and a total of 25 clusters were investigated. Investigation was performed using a 0-9 grade grading standard. The classification method is as follows:
level 0: the whole plant is free from diseases;
stage 1: fourth leaf and leaf sheath and leaf disease below (sword leaf is used as first leaf);
3 stages: a third leaf and leaf sheaths and leaf attacks below the third leaf;
5 stages: a second leaf and leaf sheaths and leaf attacks below the second leaf;
7 stages: sword leaf blade and leaf sheaths below the blade are used for disease occurrence;
stage 9: whole plants are ill and die in advance.
The drug effect calculation mode is as follows:
disease index = Σ (number of diseased stems at each stage×number of relative stages)/(total stems×9) ×100
Control effect (%) = [1- (control zone pre-drug disease index x treatment zone post-drug disease index)/(control zone post-drug disease index x treatment zone pre-drug disease index) ]x100
Test results:
TABLE 2 control Effect of Fennocoxamid and penflufen on Rhizoctonia solani by mixing
The field efficacy test shows that 7 days after the 1 st drug, the control effects of the fennocoxamid and the penflufen on the rice sheath blight disease are 67.6%, 80.0% and 76.8% respectively, which are better than the control effect of single dose; the control effect of each treatment of fennocoxamid and penflufen on rice sheath blight is 74.4%, 87.2% and 83.1% respectively, 14 days after the 2 nd medicine, which is obviously better than that of single dose.
Example 18: fennocoxamid and penflufen are mixed to prevent and treat powdery mildew of wheat
The test is based on: GB/T17980.22-2000 "pesticide field efficacy test criterion (one)" Bactericide for controlling cereal powdery mildew.
Test target: powdery mildew of wheat (Wheat powdery mildew); wheat variety "Elytrigia minor-22".
Environmental conditions: the test is set in the wheat field of Miao village on Miao county, shaanxi Bao Ji, shanxi, and is irrigated in winter for 1 time, and the management level is general.
Test agent: 20% of fennocoxamid-penflufen wettable powder, 30% of fennocoxamid-penflufen water dispersible granule and 20% of fennocoxamid-penflufen suspending agent.
Control agent: 10% of fennocoxamid suspending agent, 20% of penflufen water dispersible granule and a clear water control.
Cell area and repetition: the cell area is 20 square meters, and each treatment is repeated 4 times.
The application method comprises the following steps: the administration is started 5 months and 8 days in the initial stage of wheat powdery mildew, and a second administration is carried out 2 times after 7 days (5 months and 15 days) at intervals.
Investigation and recording: disease number was investigated before the drug (5 months and 8 days), mid-term outcome was investigated 7 days after the first drug (5 months and 15 days), and final outcome was investigated 7 days after the 2 nd drug (5 months and 22 days).
Samples were taken at 5 points diagonally per cell, 0.25 square meters were investigated per point, and one leaf per plant of flag leaf grade flag She Xiadi was investigated. The classification method is as follows:
level 0: no disease;
stage 1: the area of the disease spots accounts for less than 5% of the area of the whole leaf;
3 stages: the area of the disease spots accounts for 6% -15% of the area of the whole leaf;
5 stages: the area of the disease spots accounts for 16% -25% of the area of the whole leaf;
7 stages: the area of the disease spots accounts for 26% -50% of the area of the whole leaf;
stage 9: the area of the disease spots accounts for more than 50% of the area of the whole leaf.
The drug effect calculation mode is as follows:
disease index = Σ (number of diseased leaves at each stage×number of relative stages)/(total number of leaves×9) ×100
Control effect (%) = [1- (control zone pre-drug disease index x treatment zone post-drug disease index)/(control zone post-drug disease index x treatment zone pre-drug disease index) ]x100
Test results:
TABLE 3 control effect of fennocoxamid and penflufen on wheat powdery mildew
The test results showed (see table 3): 7 days after the last administration, the treatment of fennocoxamid and penflufen shows good prevention effect on wheat powdery mildew, which is 78.88%, 84.18% and 78.58% respectively, and the prevention effect is 74.18% and 73.90% better than that of single dose.

Claims (9)

1. The application of the bactericidal composition containing fenpicloram and penflufen in preventing and controlling crop diseases is characterized in that the bactericidal composition comprises active ingredients fenpicloram and penflufen, the weight ratio of the active ingredients fenpicloram to penflufen is 1:5-10:1, and the crop diseases are wheat powdery mildew and/or rice sheath blight.
2. Use according to claim 1, characterized in that the weight ratio of active ingredient fenpiclamid to active ingredient penflufen is 1:3-3:1.
3. Use according to claim 1, characterized in that the weight ratio of active ingredient fenpiclamid to active ingredient penflufen is 1:2.
4. Use according to claim 1, characterized in that the sum of the active ingredient contents of the composition is 1% to 90% of the total weight of the composition.
5. The use according to claim 4, wherein the sum of the active ingredient contents in the composition is 10% to 50% of the total weight of the composition.
6. The use according to claim 1, wherein the composition is formulated into any dosage form suitable for agricultural use.
7. The use according to claim 6, wherein the dosage form comprises any one of dispersible tablets, granules, soluble powders, soluble granules, soluble tablets, water dispersible granules, wettable powders, micro-encapsulated granules, powders, macro-granules, water dispersible tablets, micro-encapsulated suspensions, dispersible liquids, emulsifiable concentrates, oil emulsions, emulsifiable concentrates, aqueous emulsions, microemulsions, dispersible oil suspensions, oil dispersible powders, suspending agents, suspoemulsions, soluble solutions, ultra low volume liquids, seed-treated dry powders, seed-treated dispersible powders, seed-treated suspensions, seed-treated liquids.
8. The use according to claim 7, wherein the dosage form is wettable powder, water dispersible granule or suspension.
9. A method for controlling crop diseases, characterized in that the fungicidal composition according to any one of claims 1 to 8 is sprayed onto the surface of crops or is stirred uniformly with crop seeds.
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