CN111973486A - 一种神经酰胺滋润保湿霜及其制备方法 - Google Patents
一种神经酰胺滋润保湿霜及其制备方法 Download PDFInfo
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Abstract
本发明公开了一种神经酰胺滋润保湿霜及其制备方法，其神经酰胺滋润保湿霜，由以下组分及其重量份数比构成：组分13：β‑葡聚糖混合物1.8‑2.5；组分14：神经酰胺（3）混合物1.8‑2.5；组分15：奥氏海藻（CLADOSIPHON OKAMURANUS）提取混合物1.8‑2.5；组分16：透明质酸钠混合物1‑2；组分17：黑桑（MORUS NIGRA）根提取混合物1‑2；组分18：甘油葡糖苷0.8‑1.5；组分19：四氢甲基嘧啶羧酸0.8‑1.5；组分21：北美金缕梅（HAMAMELIS VIRGINIANA）叶提取混合物0.8‑1.5。本发明采用了纯植物提取物作为调理剂，且能够深层滋养皮肤，各药用药剂均保持在合理范围内，从而既能够保证有效调理，又不至于产生较强的副作用。
Description
技术领域
本发明涉及日化用品，特别是涉及一种神经酰胺滋润保湿霜及其制备方法。
背景技术
保湿面霜(保湿霜)是一种液态霜类化妆品，液态霜类化妆品又称蜜类化妆品，是水包油型的乳化剂，含水量在20％～80％左右，具有一定的流动性，形状颇似蜜，故而得名。保湿面霜的主要作用为去污、补充水分、补充营养，或具有控制皮肤油脂、美白的作用。
但是目前具有皮肤调理的保湿霜大多采用化学药品，甚至抗生素。这种方式虽然见效快、疗效好，但是会造成皮肤分泌物失衡且产生耐药性、依耐性，因此其副作用也很大。特别是目前形形色色的保湿霜产品，消费者由于知识面有限根本无法进行分别。就算标示存植物配方的，其由于各组分的选取、配比不当，同样会起到较大的副作用。
发明内容
有鉴于现有技术的上述缺陷，本发明所要解决的技术问题是提供一种神经酰胺滋润保湿霜及其制备方法，其采用植物配方且各组分均控制在有效范围内，从而既能够起到保养、调理的功能，又能够防止产生较大副作用。
为实现上述目的，本发明提供了一种神经酰胺滋润保湿霜，由以下组分及其重量份数比构成：
组分1：水46-50
组分2：甘油5-7
组分3：角鲨烷4-6
组分4：霍霍巴(SIMMONDSIA CHINENSIS)籽油3-5
组分5：鲸蜡硬脂基葡糖苷2-4
组分6：牛油果树(BUTYROSPERMUM PARKII)果脂2-4
组分7：辛基聚甲基硅氧烷2-4
组分8：肉豆蔻酸异丙酯2-4
组分9：生育酚(维生素E)1.8-2.5
组分10：卵磷脂1.8-2.5
组分11：碳酸二辛酯1.8-2.5
组分12：芦荟提取混合物1.8-2.5
组分13：β-葡聚糖混合物1.8-2.5
组分14：神经酰胺(3)混合物1.8-2.5
组分15：奥氏海藻(CLADOSIPHON OKAMURANUS)提取混合物1.8-2.5
组分16：透明质酸钠混合物1-2
组分17：黑桑(MORUS NIGRA)根提取混合物1-2
组分18：甘油葡糖苷0.8-1.5
组分19：四氢甲基嘧啶羧酸0.8-1.5
组分20：水解小核菌(SCLEROTIUM ROLFSSII)胶0.8-1.5
组分21：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取混合物0.8-1.5
组分22：烟酰胺0.6-1
组分23：肌肽0.6-1
组分24：丙烯酸(酯)类交联聚合物0.4-0.6
组分25：甘草酸二钾0.4-0.6
组分26：对羟基苯乙酮混合物0.4-0.6
组分27：红没药醇0.06-0.12
组分28：香精0.008-0.012；
组分14：神经酰胺(3)混合物由以下组分及其重量份数比为构成：神经酰胺(3)28-32、氢化卵磷脂68-72；
组分15：奥氏海藻(CLADOSIPHON OKAMURANUS)提取混合物由以下组分及其重量份数比为构成：奥氏海藻(CLADOSIPHON OKAMURANUS)提取物28-32、甘油38-42、水26-34；
组分16：透明质酸钠混合物由以下组分及其重量份数比为构成：透明质酸钠9-11、水89-91；
组分17：黑桑(MORUS NIGRA)根提取混合物由以下组分及其重量份数比为构成：黑桑(MORUS NIGRA)根提取物28-32、1,2-己二醇28-32、水36-46；
组分21：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取混合物由以下组分及其重量份数比为构成：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取物38-42、丁二醇28-32、水26-34。
组分1作为溶剂，用于将各组分溶解、混合；
组分2作为保湿剂，甘油又称丙三醇，柔软、保湿、卸妆溶剂及润滑剂。绝不可直接使用未经稀释的100％纯甘油，会造成反效果。甘油具有吸水作用，保湿护肤品常常用它吸附空气中的水分子，令其覆盖的皮肤角质层保持湿润。但是纯甘油的保湿效果容易受到空气中湿度的影响。
组分3作为润肤剂，角鲨烷提取自深海鲨鱼肝脏或橄榄油中，是皮肤一种天然成分，具有较好抗氧化力和刺激免疫力，能快速地与肌肤内的水分和油脂相溶，形成天然的皮肤保护屏障，稳定性极佳，不会与空气、紫外线等发生氧化作用，能有效保护皮肤不受外界物质的侵害，极佳的渗透力，高效的携氧性，能调整肌肤的水油平衡，避免肌肤粗糙、暗沉，恢复肌肤原本的柔嫩触感。尤其适合在寒冷季节中使用，是肌肤的润滑油，能补充皮肤天然皮脂。
组分4作为润肤剂，霍霍巴(SIMMONDSIA CHINENSIS)籽油不易被氧化，耐高温、高压、黏度变化小。其触觉和延展性也比其他植物油好，对皮肤有柔软弹性感，且易被皮肤吸收，是化妆品中出色的油剂、滋润剂和保湿剂。
组分5作为乳化剂，鲸蜡硬脂基葡糖苷可以增强产品的保湿效果，质感清爽，常使用于膏霜、防晒产品中。
组分6作为润肤剂，牛油果树(BUTYROSPERMUM PARKII)果脂从牛油果树的果实中提取而成，含有丰富的不饱和脂肪酸，能够加强皮肤的保湿能力，对干性皮肤即角质受损的肌肤能加以滋润。同时可以调节产品的流动性，改善粘度，提高产品的感官品质和使用肤感。
组分7作为润肤剂，辛基聚甲基硅氧烷在化妆品中作皮肤调理剂和润滑剂使用，可以增加产品质感，使其清爽并易于涂抹。
组分8作为润肤剂，肉豆蔻酸异丙酯在作粘合剂、柔润剂和角质软化剂使用，添加该成分的产品更易涂抹，并质感清爽。该成分分子小，易渗透，作卸妆用途清洁效果好。但该成分过度使用会使皮肤粗糙蜡黄，有一定的刺激性和致暗疮粉刺性。
组分9作为润肤剂，生育酚(维生素E)是对两种化学物质：生育醇与三烯生育醇的总称，这两种化学物质在体内的生物作用大致相同，只是活性不同而已。生育醇与三烯生育醇都各有四种：alpha、beta、gamma、以及delta，其间的差异是甲基在酚环上的数量与位置；三烯生育醇的差异则在其不饱和的侧链。三烯生育醇(Tocotrienols)属于维他命E的一种。与维他命E相同，三烯生育醇也是相当强的抗氧化剂，能对抗脂质过氧化反应。
组分10作为润肤剂，卵磷脂主要提取自蛋黄和黄豆中，该成分是人体细胞不可缺少的物质，若缺乏会降低皮肤细胞再生能力，导致皮肤粗糙，皱纹等。卵磷脂具有保湿和抗氧化作用，化妆品中添加该成分能给皮肤再生活力予以保障，并且该成分有良好的亲水性和亲油性，使用后会增添皮肤光泽。
组分11作为润肤剂，碳酸二辛酯为防晒产品中的添加物，无色且溶解性强，作柔润剂和分散剂使用。该成分易乳化，能够促进产品易于涂抹，可以使皮肤形成保护膜，并且光滑不油腻，留有丝滑触感。
组分12作为皮肤调理剂，其芦荟提取物具有多方面的生物活性，是化妆品重要的添加剂。从芦荟提取物对纤维蛋白增长的促进作用、对弹性蛋白的抑制、对胶原蛋白的合成以及对自由基的清除作用，说明有很好的活肤、抗老化在作用；对胆甾醇合成有促进作用，有助于改变皮脂的组成，减少油光和增加皮肤的柔润程度；同时具有抗菌消炎和保湿的作用。
组分13作为皮肤调理剂，其β-葡聚糖为天然植物胶聚糖，在化妆品中皮肤调理剂和保湿剂使用，同时该成分还有一定抗敏抗炎等作用。该成分为水溶性，能与大多数原料有较好配伍性，无过敏反应，还能提高皮肤保湿能力。该成分还能起到抗氧化和保护皮肤免受紫外线伤害的作用，能够减少皮肤皱纹，提高皮肤抵御外界伤害的能力。
组分14作为润肤剂，其神经酰胺(3)一种脂质物质，人工合成成分，它和构成皮肤角质层的物质结构相近，能很快渗透进皮肤，帮助皮肤天然保护层的更新，能促进自然水合作用的平衡，和角质层中的水结合，形成一种网状结构，锁住水分。对肌肤保湿修护有良好作用，是角质层中重要的活肤成分，能增强皮肤屏障，重建细胞，形成有效的屏障来防止水分流失和减少外部环境的影响。受刺激的皮肤尤其需要更多的神经酰胺，有研究表明，擦含有神经酰胺成分的产品能减少红肿和经皮水分流失，起到增强皮肤屏障并帮助受损肌肤缓解干燥状态的作用。其氢化卵磷脂是卵磷脂的部分水解物，氢化卵磷脂提高了它的亲水能力。为人的皮肤和毛发吸收并能促进其他营养物质的渗透，常与亚麻酸、透明质酸、维生素类共用于调理型化妆品，卵磷脂乳化作用强，能稳定乳状液，适用于配制凝胶型产品。
组分15作为皮肤调理剂，其奥氏海藻(CLADOSIPHON OKAMURANUS)提取物营养丰富又具保健作用，含叶绿素a和c、胡萝卜素及数种叶黄素,淀粉、甘露醇和脂类等，亦含有大量的维生素及无机盐类(天然抗氧化，延缓衰老，美白成分)，也相当适合作为肌肤调理之用。
组分16作为保湿剂，其透明质酸钠又称玻尿酸钠，属于肌肤调理剂，是一种酸性粘多糖，天然存在于角膜皮中，可吸收其本身重量1000倍水分，以达到通过保留皮肤水分、阻止水分经表皮流失，以及当皮肤受到损伤时的屏障修复，令皮肤使用后不会感到干燥，增加光泽，它可以改善皮肤营养代谢，使皮肤柔、光滑、去皱、增加弹性、防止衰老，在保湿的同时又是良好的透皮吸收促进剂。与其他营养成分配合使用，可以起到促进营养吸收的更理想效果。
组分17作为皮肤调理剂，其黑桑(MORUS NIGRA)根提取物含还原糖，多缩戊糖及半乳糖酐，鞣质，黄酮类等。能抑制弹性蛋白酶，有抗衰的作用；促进纤维芽细胞脑酰胺的合成，柔润皮肤；对因雄性激素偏高引发的痤疮能很好的防治；对胶原纤维有收缩作用，可以用于瘦身；对荧光素酶的活化有促进作用，说明具有抗炎的功效；能抑制酪氨酸酶的活性，具有美白的功效。
组分18作为润肤剂，甘油葡糖苷是一类由甘油与葡萄糖分子以糖苷键结合的物质，具有保湿、抗氧化功能。
组分19作为皮肤调理剂，四氢甲基嘧啶羧酸又称Ectoin(依克多因)，作为一种渗透压补偿性溶质存在于耐盐菌中，在细胞内起到化学递质样作用，对细胞在逆环境中有稳定性的保护作用，也能稳定生物体内酶蛋白的结构，有活肤抗衰的功能；可提供良好的保湿和防晒功能，并有美白皮肤的作用；四氢甲基嘧啶羧酸也可保护中性粒细胞，显示有抗炎作用。
组分20作为皮肤调理剂，水解小核菌(SCLEROTIUM ROLFSSII)胶是多糖类的天然聚合物，也叫硬葡聚糖，高温多种PH值下都很稳定，又是多糖聚合物，与皮肤相容性好，能有效成膜，且稳定性。
组分21作为皮肤调理剂，其北美金缕梅(HAMAMELIS VIRGINIANA)叶提取物在抗氧化、提高皮层局部雌激素水平等方面可增强皮肤细胞新陈代谢，有抗衰作用，可维持皮肤弹性和抗皱；具有抗炎，防敏舒缓和收敛的作用；还有良好的持水能力。
组分22作为皮肤调理剂，烟酰胺又称维生素B3，作为一种医药成分来说具有很高的安全性，也是临床皮肤科治疗中的一种基础性维生素类补充剂，较为广泛地备用于治疗光敏性皮炎、痤疮等。近年来的研究证明，它在抑制黑色素沉着、抗炎等方面也有很好的疗效；基于这一特征，烟酰胺在化妆品领域的应用得到了进一步延伸，除了传统的美白效果之外，也被用于减少已经生成、沉淀的黑色素，阻隔其向表层细胞的转移，加速细胞新陈代谢、加快黑色素角质细胞脱落等。烟酰胺能够维持肌肤含水量，促进真皮层微循环。烟酰胺还能极大减少或消除皮肤老化现象，比如皱纹、起皮、毛孔粗大等，减少自由基对皮肤的伤害，起到预防老化、修复皮肤和减少面部暗沉的作用。
组分23作为皮肤调理剂，成纤维细胞在肌肽的稀水溶液中存活时间明显延长，这说明肌肽不仅是营养剂，同时又能促进细胞的新陈代弋谢，延缓衰老。药用膏霜中用入作为愈伤促进剂。肌肽能俘获游离氧自由基，特别有效地防止蛋白质类成分的氧化，有增白功能；与尿刊酸共用可预防光敏性皮炎；肌肽也易为皮肤、头发和头皮吸收,并有助渗作用。
组分24作为增稠剂，丙烯酸(酯)类交联聚合物可以吸附各组分，使得各成品粘稠。
组分25作为皮肤调理剂，甘草酸二钾是作为皮肤调理剂使用，主要为甘草根部及茎部的甘草甜素(甘草酸)成分适合过敏性肌肤，抗刺激及控油，退红肿消炎愈合作用。可有效预防皮肤受刺激时敏感发炎现象。对日照引起的炎症具有消炎镇静作用，常被用于抗过敏及修复化妆品中。
组分26作为溶剂，其对羟基苯乙酮一种天然植物提取物，天然存在于菊科植物滨蒿的茎、叶，茵陈蒿、萝藦科植物、人参娃儿藤等植物的根中。具有抗氧化和舒缓作用的多功能化妆品成分；在化妆品中，同时可作为传统防腐剂的替代品，具有防腐增效的作用，能够促进各种防腐剂功效，在高低pH和温度范围内都有优异的稳定性。可用于各类配方，包括防晒和香波。它与各种化妆品成分和包材都有很好的兼容性。其异戊二醇是多功能化妆品添加剂，也是一种效果显著的除臭成份。可以增强醇类与二元醇的抗菌性能，并增效传统的防腐体系。同时也具有润肤和温和保湿功效，可改善化妆品配方的肤感。其1,2-己二醇位保湿剂，属于多元醇，具有抑菌效果，只有当添加量在5％左右时才有防腐效果，但不等同于防腐剂。
组分27作为皮肤调理剂，红没药醇从菊类植物中提取，有抗炎抑菌的作用，该成分稳定性好，和皮肤有很好的相容性，降低皮肤炎症，减轻皮肤粉刺，防止暗疮产生，提高皮肤的抗刺激能力，修复有炎症受伤的皮肤，在防晒产品中提高SPF值。红没药醇有明显的抗炎和抗痉作用，在此功能上，天然红没药醇的作用是合成品的二倍，有止痛、缓和刺激和抗过敏功能，对过敏性皮肤或儿童皮肤均有护肤效应。红没药醇有镇静和抗出汗效应，常用于防晒制品和治疗日晒伤和烧伤的油膏；有广谱的抗菌性，牙膏中用入可减少齿斑和牙龈过敏，可防治口臭；红没药醇在皮肤皮层有高渗透性，作用是常用渗透剂的几十倍；可作为主剂或助剂用于防治粉刺一类的皮肤疾病，对皮肤还有调理作用。
组分28作为芳香剂，用于提供香味。
各组分的INCI名称如下：
上述神经酰胺滋润保湿霜的制备方法，包括如下步骤：
S1、依次将组分1、组分2、组分21、组分26投入乳化锅水相锅中搅拌，加热至80-90℃并保持20分钟以上，获得第一中间体；
S2、依次将组分3、组分4、组分5、组分6、组分7、组分8、组分9、组分10、组分11投入油相锅中搅拌，加热至75-80℃并保持20分钟以上，获得第二中间体；
S3、将加热好的第一中间体开真空抽入主乳化锅中，然后再抽入第二中间体，均质5-10分钟，保温20分钟以上获得第三中间体；
S4、打开冷却水，第三中间体降温至65-70℃，加入组分24、组分25、组分，搅拌溶解，获得第四中间体；
S5、第四中间体降温至55-60℃后依次加入组分15、组分17，然后搅拌溶解，获得第五中间体；
S6、第五中间体降温至40-45℃后依次加入组分12、组分13、组分14、组分16、组分18、组分19、组分20、组分22、组分23、组分28，然后搅拌溶解完全，获得成品；
S7、成品降温至35-38℃，停止搅拌，出料。各组分由于能够承受为温度不一样，且需要根据相似相溶原理逐个将各个组分溶解、混合，因此申请人设计了上述制备方式。其能够在保证各个组分充分溶解混合的前提下还保证各个组分的活性，从而保证最终成品的功效。
本发明的有益效果是：本发明采用了纯植物提取物作为调理剂，且能够深层滋养皮肤，各药用药剂均保持在合理范围内，从而既能够保证有效调理，又不至于产生较强的副作用。
本发明能够保湿滋润，肤感清爽，不粘腻，滋润度好，保湿时间长，很好修护受损皮肤。另外神经酰胺是用纳米包裹的，能更好的提高皮肤吸收效果，能更有效的渗透到皮肤深层。
具体实施方式
下面结合实施例对本发明作进一步说明：
实施例一
一种神经酰胺滋润保湿霜，由以下组分及其重量份数比构成：
组分1：水48.59
组分2：甘油6
组分3：角鲨烷5
组分4：霍霍巴(SIMMONDSIA CHINENSIS)籽油4
组分5：鲸蜡硬脂基葡糖苷3
组分6：牛油果树(BUTYROSPERMUM PARKII)果脂3
组分7：辛基聚甲基硅氧烷3
组分8：肉豆蔻酸异丙酯3
组分9：生育酚(维生素E)2.2
组分10：卵磷脂2
组分11：碳酸二辛酯2
组分12：芦荟提取混合物2
组分13：β-葡聚糖混合物2
组分14：神经酰胺(3)混合物2
组分15：奥氏海藻(CLADOSIPHON OKAMURANUS)提取混合物2
组分16：透明质酸钠混合物1.5
组分17：黑桑(MORUS NIGRA)根提取混合物1.5
组分18：甘油葡糖苷1
组分19：四氢甲基嘧啶羧酸1
组分20：水解小核菌(SCLEROTIUM ROLFSSII)胶1
组分21：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取混合物1
组分22：烟酰胺0.8
组分23：肌肽0.8
组分24：丙烯酸(酯)类交联聚合物0.5
组分25：甘草酸二钾0.5
组分26：对羟基苯乙酮混合物0.5
组分27：红没药醇0.1
组分28：香精0.01；
组分14：神经酰胺(3)混合物由以下组分及其重量份数比为构成：神经酰胺(3)30、氢化卵磷脂70；
组分15：奥氏海藻(CLADOSIPHON OKAMURANUS)提取混合物由以下组分及其重量份数比为构成：奥氏海藻(CLADOSIPHON OKAMURANUS)提取物30、甘油40、水30；
组分16：透明质酸钠混合物由以下组分及其重量份数比为构成：透明质酸钠10、水90；
组分17：黑桑(MORUS NIGRA)根提取混合物由以下组分及其重量份数比为构成：黑桑(MORUS NIGRA)根提取物30、1,2-己二醇30、水40；
组分21：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取混合物由以下组分及其重量份数比为构成：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取物40、丁二醇30、水30。
实施例二
一种神经酰胺滋润保湿霜，由以下组分及其重量份数比构成：
组分1：水48
组分2：甘油6.2
组分3：角鲨烷4.8
组分4：霍霍巴(SIMMONDSIA CHINENSIS)籽油4.8
组分5：鲸蜡硬脂基葡糖苷3.5
组分6：牛油果树(BUTYROSPERMUM PARKII)果脂3.5
组分7：辛基聚甲基硅氧烷3.5
组分8：肉豆蔻酸异丙酯3.5
组分9：生育酚(维生素E)2.2
组分10：卵磷脂2.2
组分11：碳酸二辛酯2.2
组分12：芦荟提取混合物2.2
组分13：β-葡聚糖混合物2.2
组分14：神经酰胺(3)混合物2.2
组分15：奥氏海藻(CLADOSIPHON OKAMURANUS)提取混合物2.2
组分16：透明质酸钠混合物1.8
组分17：黑桑(MORUS NIGRA)根提取混合物1.8
组分18：甘油葡糖苷1.2
组分19：四氢甲基嘧啶羧酸1.2
组分20：水解小核菌(SCLEROTIUM ROLFSSII)胶1.2
组分21：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取混合物1.2
组分22：烟酰胺0.8
组分23：肌肽0.8
组分24：丙烯酸(酯)类交联聚合物0.55
组分25：甘草酸二钾0.55
组分26：对羟基苯乙酮混合物0.55
组分27：红没药醇0.08
组分28：香精0.009；
组分14：神经酰胺(3)混合物由以下组分及其重量份数比为构成：神经酰胺(3)29、氢化卵磷脂71；
组分15：奥氏海藻(CLADOSIPHON OKAMURANUS)提取混合物由以下组分及其重量份数比为构成：奥氏海藻(CLADOSIPHON OKAMURANUS)提取物29、甘油39、水32；
组分16：透明质酸钠混合物由以下组分及其重量份数比为构成：透明质酸钠9、水91；
组分17：黑桑(MORUS NIGRA)根提取混合物由以下组分及其重量份数比为构成：黑桑(MORUS NIGRA)根提取物29、1,2-己二醇29、水42；
组分21：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取混合物由以下组分及其重量份数比为构成：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取物39、丁二醇29、水32。
实施例三
一种神经酰胺滋润保湿霜，由以下组分及其重量份数比构成：
组分1：水49
组分2：甘油5.5
组分3：角鲨烷4.5
组分4：霍霍巴(SIMMONDSIA CHINENSIS)籽油3.8
组分5：鲸蜡硬脂基葡糖苷3.8
组分6：牛油果树(BUTYROSPERMUM PARKII)果脂3.8
组分7：辛基聚甲基硅氧烷3.8
组分8：肉豆蔻酸异丙酯3.8
组分9：生育酚(维生素E)2.4
组分10：卵磷脂2.4
组分11：碳酸二辛酯2.4
组分12：芦荟提取混合物2.4
组分13：β-葡聚糖混合物2.4
组分14：神经酰胺(3)混合物2.4
组分15：奥氏海藻(CLADOSIPHON OKAMURANUS)提取混合物2.4
组分16：透明质酸钠混合物1.6
组分17：黑桑(MORUS NIGRA)根提取混合物1.6
组分18：甘油葡糖苷1.4
组分19：四氢甲基嘧啶羧酸1.4
组分20：水解小核菌(SCLEROTIUM ROLFSSII)胶1.4
组分21：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取混合物1.4
组分22：烟酰胺0.75
组分23：肌肽0.75
组分24：丙烯酸(酯)类交联聚合物0.48
组分25：甘草酸二钾0.48
组分26：对羟基苯乙酮混合物0.48
组分27：红没药醇0.09
组分28：香精0.012；
组分14：神经酰胺(3)混合物由以下组分及其重量份数比为构成：神经酰胺(3)31、氢化卵磷脂69；
组分15：奥氏海藻(CLADOSIPHON OKAMURANUS)提取混合物由以下组分及其重量份数比为构成：奥氏海藻(CLADOSIPHON OKAMURANUS)提取物31、甘油41、水28；
组分16：透明质酸钠混合物由以下组分及其重量份数比为构成：透明质酸钠11、水89；
组分17：黑桑(MORUS NIGRA)根提取混合物由以下组分及其重量份数比为构成：黑桑(MORUS NIGRA)根提取物31、1,2-己二醇31、水38；
组分21：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取混合物由以下组分及其重量份数比为构成：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取物41、丁二醇31、水28。
实施例四
神经酰胺滋润保湿霜的制备方法，包括如下步骤：
S1、依次将组分1、组分2、组分21、组分26投入乳化锅水相锅中搅拌，搅拌速度50转/分钟，加热至90℃并保持20分钟以上，获得第一中间体；
S2、依次将组分3、组分4、组分5、组分6、组分7、组分8、组分9、组分10、组分11投入油相锅中搅拌，搅拌速度50转/分钟，搅拌加热至80℃并保持20分钟以上，获得第二中间体；
S3、将加热好的第一中间体开真空抽入主乳化锅中，开均质3000转/分钟，然后再抽入第二中间体，均质5分钟，搅拌开40转/分钟，保温20分钟以上获得第三中间体；
S4、打开冷却水，第三中间体降温至70℃，加入组分24、组分25、组分，均质5分钟，均质3000转/分钟，获得第四中间体；
S5、第四中间体降温至60℃后依次加入组分15、组分17，然后搅拌溶解，获得第五中间体；
S6、第五中间体降温至45℃后依次加入组分12、组分13、组分14、组分16、组分18、组分19、组分20、组分22、组分23、组分28，然后搅拌溶解完全，获得成品；
S7、成品降温至38℃，停止搅拌，出料。
本发明未详述之处，均为本领域技术人员的公知技术。
以上详细描述了本发明的较佳具体实施例。应当理解，本领域的普通技术人员无需创造性劳动就可以根据本发明的构思作出诸多修改和变化。因此，凡本技术领域中技术人员依本发明的构思在现有技术的基础上通过逻辑分析、推理或者有限的实验可以得到的技术方案，皆应在由权利要求书所确定的保护范围内。
Claims (9)
1.一种神经酰胺滋润保湿霜，其特征在于，由以下组分及其重量份数比构成：
组分13：β-葡聚糖混合物1.8-2.5
组分14：神经酰胺(3)混合物1.8-2.5
组分15：奥氏海藻(CLADOSIPHON OKAMURANUS)提取混合物1.8-2.5
组分16：透明质酸钠混合物1-2
组分17：黑桑(MORUS NIGRA)根提取混合物1-2
组分18：甘油葡糖苷0.8-1.5
组分19：四氢甲基嘧啶羧酸0.8-1.5
组分21：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取混合物0.8-1.5。
2.如权利要求1所述的神经酰胺滋润保湿霜，其特征在于，还包括以下组分及其重量份数比：
组分1：水46-50
组分2：甘油5-7
组分3：角鲨烷4-6
组分4：霍霍巴(SIMMONDSIA CHINENSIS)籽油3-5
组分5：鲸蜡硬脂基葡糖苷2-4
组分6：牛油果树(BUTYROSPERMUM PARKII)果脂2-4
组分7：辛基聚甲基硅氧烷2-4
组分8：肉豆蔻酸异丙酯2-4
组分9：生育酚(维生素E)1.8-2.5
组分10：卵磷脂1.8-2.5
组分11：碳酸二辛酯1.8-2.5
组分12：芦荟提取混合物1.8-2.5
组分20：水解小核菌(SCLEROTIUM ROLFSSII)胶0.8-1.5
组分22：烟酰胺0.6-1
组分23：肌肽0.6-1
组分24：丙烯酸(酯)类交联聚合物0.4-0.6
组分25：甘草酸二钾0.4-0.6
组分26：对羟基苯乙酮混合物0.4-0.6
组分27：红没药醇0.06-0.12。
3.如权利要求2所述的神经酰胺滋润保湿霜，其特征在于，还包括以下组分及其重量份数比：
组分28：香精0.008-0.012。
4.如权利要求3所述的神经酰胺滋润保湿霜，其特征在于，组分14：神经酰胺(3)混合物由以下组分及其重量份数比为构成：神经酰胺(3)28-32、氢化卵磷脂68-72；
组分15：奥氏海藻(CLADOSIPHON OKAMURANUS)提取混合物由以下组分及其重量份数比为构成：奥氏海藻(CLADOSIPHON OKAMURANUS)提取物28-32、甘油38-42、水26-34；
组分16：透明质酸钠混合物由以下组分及其重量份数比为构成：透明质酸钠9-11、水89-91；
组分17：黑桑(MORUS NIGRA)根提取混合物由以下组分及其重量份数比为构成：黑桑(MORUS NIGRA)根提取物28-32、1,2-己二醇28-32、水36-46；
组分21：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取混合物由以下组分及其重量份数比为构成：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取物38-42、丁二醇28-32、水26-34。
5.如权利要求4所述的神经酰胺滋润保湿霜，其特征在于，由以下组分及其重量份数比构成：
组分1：水48.59
组分2：甘油6
组分3：角鲨烷5
组分4：霍霍巴(SIMMONDSIA CHINENSIS)籽油4
组分5：鲸蜡硬脂基葡糖苷3
组分6：牛油果树(BUTYROSPERMUM PARKII)果脂3
组分7：辛基聚甲基硅氧烷3
组分8：肉豆蔻酸异丙酯3
组分9：生育酚(维生素E)2.2
组分10：卵磷脂2
组分11：碳酸二辛酯2
组分12：芦荟提取混合物2
组分13：β-葡聚糖混合物2
组分14：神经酰胺(3)混合物2
组分15：奥氏海藻(CLADOSIPHON OKAMURANUS)提取混合物2
组分16：透明质酸钠混合物1.5
组分17：黑桑(MORUS NIGRA)根提取混合物1.5
组分18：甘油葡糖苷1
组分19：四氢甲基嘧啶羧酸1
组分20：水解小核菌(SCLEROTIUM ROLFSSII)胶1
组分21：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取混合物1
组分22：烟酰胺0.8
组分23：肌肽0.8
组分24：丙烯酸(酯)类交联聚合物0.5
组分25：甘草酸二钾0.5
组分26：对羟基苯乙酮混合物0.5
组分27：红没药醇0.1
组分28：香精0.01；
组分14：神经酰胺(3)混合物由以下组分及其重量份数比为构成：神经酰胺(3)30、氢化卵磷脂70；
组分15：奥氏海藻(CLADOSIPHON OKAMURANUS)提取混合物由以下组分及其重量份数比为构成：奥氏海藻(CLADOSIPHON OKAMURANUS)提取物30、甘油40、水30；
组分16：透明质酸钠混合物由以下组分及其重量份数比为构成：透明质酸钠10、水90；
组分17：黑桑(MORUS NIGRA)根提取混合物由以下组分及其重量份数比为构成：黑桑(MORUS NIGRA)根提取物30、1,2-己二醇30、水40；
组分21：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取混合物由以下组分及其重量份数比为构成：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取物40、丁二醇30、水30。
6.如权利要求4所述的神经酰胺滋润保湿霜，其特征在于，由以下组分及其重量份数比构成：
组分1：水48
组分2：甘油6.2
组分3：角鲨烷4.8
组分4：霍霍巴(SIMMONDSIA CHINENSIS)籽油4.8
组分5：鲸蜡硬脂基葡糖苷3.5
组分6：牛油果树(BUTYROSPERMUM PARKII)果脂3.5
组分7：辛基聚甲基硅氧烷3.5
组分8：肉豆蔻酸异丙酯3.5
组分9：生育酚(维生素E)2.2
组分10：卵磷脂2.2
组分11：碳酸二辛酯2.2
组分12：芦荟提取混合物2.2
组分13：β-葡聚糖混合物2.2
组分14：神经酰胺(3)混合物2.2
组分15：奥氏海藻(CLADOSIPHON OKAMURANUS)提取混合物2.2
组分16：透明质酸钠混合物1.8
组分17：黑桑(MORUS NIGRA)根提取混合物1.8
组分18：甘油葡糖苷1.2
组分19：四氢甲基嘧啶羧酸1.2
组分20：水解小核菌(SCLEROTIUM ROLFSSII)胶1.2
组分21：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取混合物1.2
组分22：烟酰胺0.8
组分23：肌肽0.8
组分24：丙烯酸(酯)类交联聚合物0.55
组分25：甘草酸二钾0.55
组分26：对羟基苯乙酮混合物0.55
组分27：红没药醇0.08
组分28：香精0.009；
组分14：神经酰胺(3)混合物由以下组分及其重量份数比为构成：神经酰胺(3)29、氢化卵磷脂71；
组分15：奥氏海藻(CLADOSIPHON OKAMURANUS)提取混合物由以下组分及其重量份数比为构成：奥氏海藻(CLADOSIPHON OKAMURANUS)提取物29、甘油39、水32；
组分16：透明质酸钠混合物由以下组分及其重量份数比为构成：透明质酸钠9、水91；
组分17：黑桑(MORUS NIGRA)根提取混合物由以下组分及其重量份数比为构成：黑桑(MORUS NIGRA)根提取物29、1,2-己二醇29、水42；
组分21：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取混合物由以下组分及其重量份数比为构成：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取物39、丁二醇29、水32。
7.如权利要求4所述的神经酰胺滋润保湿霜，其特征在于，由以下组分及其重量份数比构成：
组分1：水49
组分2：甘油5.5
组分3：角鲨烷4.5
组分4：霍霍巴(SIMMONDSIA CHINENSIS)籽油3.8
组分5：鲸蜡硬脂基葡糖苷3.8
组分6：牛油果树(BUTYROSPERMUM PARKII)果脂3.8
组分7：辛基聚甲基硅氧烷3.8
组分8：肉豆蔻酸异丙酯3.8
组分9：生育酚(维生素E)2.4
组分10：卵磷脂2.4
组分11：碳酸二辛酯2.4
组分12：芦荟提取混合物2.4
组分13：β-葡聚糖混合物2.4
组分14：神经酰胺(3)混合物2.4
组分15：奥氏海藻(CLADOSIPHON OKAMURANUS)提取混合物2.4
组分16：透明质酸钠混合物1.6
组分17：黑桑(MORUS NIGRA)根提取混合物1.6
组分18：甘油葡糖苷1.4
组分19：四氢甲基嘧啶羧酸1.4
组分20：水解小核菌(SCLEROTIUM ROLFSSII)胶1.4
组分21：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取混合物1.4
组分22：烟酰胺0.75
组分23：肌肽0.75
组分24：丙烯酸(酯)类交联聚合物0.48
组分25：甘草酸二钾0.48
组分26：对羟基苯乙酮混合物0.48
组分27：红没药醇0.09
组分28：香精0.012；
组分14：神经酰胺(3)混合物由以下组分及其重量份数比为构成：神经酰胺(3)31、氢化卵磷脂69；
组分15：奥氏海藻(CLADOSIPHON OKAMURANUS)提取混合物由以下组分及其重量份数比为构成：奥氏海藻(CLADOSIPHON OKAMURANUS)提取物31、甘油41、水28；
组分16：透明质酸钠混合物由以下组分及其重量份数比为构成：透明质酸钠11、水89；
组分17：黑桑(MORUS NIGRA)根提取混合物由以下组分及其重量份数比为构成：黑桑(MORUS NIGRA)根提取物31、1,2-己二醇31、水38；
组分21：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取混合物由以下组分及其重量份数比为构成：北美金缕梅(HAMAMELIS VIRGINIANA)叶提取物41、丁二醇31、水28。
8.一种神经酰胺滋润保湿霜的制备方法，其特征在于，包括如下步骤：
S1、依次将组分1、组分2、组分21、组分26投入乳化锅水相锅中搅拌，加热至80-90℃并保持20分钟以上，获得第一中间体；
S2、依次将组分3、组分4、组分5、组分6、组分7、组分8、组分9、组分10、组分11投入油相锅中搅拌，加热至75-80℃并保持20分钟以上，获得第二中间体；
S3、将加热好的第一中间体开真空抽入主乳化锅中，然后再抽入第二中间体，均质5-10分钟，保温20分钟以上获得第三中间体；
S4、打开冷却水，第三中间体降温至65-70℃，加入组分24、组分25、组分，搅拌溶解，获得第四中间体；
S5、第四中间体降温至55-60℃后依次加入组分15、组分17，然后搅拌溶解，获得第五中间体；
S6、第五中间体降温至40-45℃后依次加入组分12、组分13、组分14、组分16、组分18、组分19、组分20、组分22、组分23、组分28，然后搅拌溶解完全，获得成品；
S7、成品降温至35-38℃，停止搅拌，出料。
9.如权利要求8所述的制备方法，其特征在于，包括如下步骤：
S1、依次将组分1、组分2、组分21、组分26投入乳化锅水相锅中搅拌，搅拌速度50转/分钟，加热至90℃并保持20分钟以上，获得第一中间体；
S2、依次将组分3、组分4、组分5、组分6、组分7、组分8、组分9、组分10、组分11投入油相锅中搅拌，搅拌速度50转/分钟，搅拌加热至80℃并保持20分钟以上，获得第二中间体；
S3、将加热好的第一中间体开真空抽入主乳化锅中，开均质3000转/分钟，然后再抽入第二中间体，均质5分钟，搅拌开40转/分钟，保温20分钟以上获得第三中间体；
S4、打开冷却水，第三中间体降温至70℃，加入组分24、组分25、组分，均质5分钟，均质3000转/分钟，获得第四中间体；
S5、第四中间体降温至60℃后依次加入组分15、组分17，然后搅拌溶解，获得第五中间体；
S6、第五中间体降温至45℃后依次加入组分12、组分13、组分14、组分16、组分18、组分19、组分20、组分22、组分23、组分28，然后搅拌溶解完全，获得成品；
S7、成品降温至38℃，停止搅拌，出料。
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