CN111887905A - Biopsy forceps for digging living tissue - Google Patents
Biopsy forceps for digging living tissue Download PDFInfo
- Publication number
- CN111887905A CN111887905A CN202010722101.5A CN202010722101A CN111887905A CN 111887905 A CN111887905 A CN 111887905A CN 202010722101 A CN202010722101 A CN 202010722101A CN 111887905 A CN111887905 A CN 111887905A
- Authority
- CN
- China
- Prior art keywords
- digging
- living tissue
- knife
- biopsy forceps
- digging knife
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/06—Biopsy forceps, e.g. with cup-shaped jaws
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/025—Pointed or sharp biopsy instruments for taking bone, bone marrow or cartilage samples
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Medical Informatics (AREA)
- Veterinary Medicine (AREA)
- Pathology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Surgical Instruments (AREA)
Abstract
本发明公开了一种用于挖取活体组织的活检钳,属于医疗器械技术领域。本发明的一种用于挖取活体组织的活检钳,包括活检钳主体,所述活检钳主体的动杆可沿其定杆作前后运动,还包括设置于所述动杆的前端位置的挖刀,所述挖刀的前端具有可挖入患者机体的刀刃;当活检钳主体使动杆作向前运动时,所述动杆将驱动所述挖刀向前运动,挖刀作出挖取动作,用以挖取活体组织。采用本发明的一种用于挖取活体组织的活检钳,当活检钳主体使动杆作向前运动时,动杆将驱动挖刀向前运动,通过挖刀的挖取动作实现在患者机体上挖取活体组织,能够有效实现活体组织的采集,并提高活体组织的采集量,进而能够提高活检检查结果的准确性。
The invention discloses a biopsy forceps for digging out living tissue, which belongs to the technical field of medical instruments. A biopsy forceps used for digging out living tissue of the present invention includes a biopsy forceps main body, a movable rod of the biopsy forceps body can move back and forth along the fixed rod, and a digging hole disposed at the front end of the movable rod. A knife, the front end of the digging knife has a blade that can dig into the body of the patient; when the main body of the biopsy forceps makes the moving rod move forward, the moving rod will drive the digging knife to move forward, and the digging knife makes a digging action , used to excavate living tissue. By adopting the biopsy forceps for digging out living tissue of the present invention, when the main body of the biopsy forceps makes the moving rod move forward, the moving rod will drive the digging knife to move forward, and the digging action of the digging knife realizes the digging action of the digging knife in the patient's body. By digging up the living tissue, the collection of the living tissue can be effectively realized, and the collection amount of the living tissue can be increased, thereby improving the accuracy of the biopsy inspection result.
Description
技术领域technical field
本发明涉及一种用于挖取活体组织的活检钳,属于医疗器械技术领域。The invention relates to a biopsy forceps for excavating living tissue, belonging to the technical field of medical instruments.
背景技术Background technique
活检是“活体组织检查”简称,亦称外科病理学检查,是指应诊断、治疗的需要,从患者机体上切取、钳取或穿刺等取出病变活体组织,并进行病理学检查的技术。Biopsy is the abbreviation of "biopsy examination", also known as surgical pathological examination, which refers to the technology of removing diseased living tissue from the patient's body, such as cutting, clamping or puncturing, and performing pathological examination according to the needs of diagnosis and treatment.
活检钳是取出病变活体组织所不可缺少的工具,现有技术中已有大量的设计。例如,中国专利:一种宫颈活检钳(公开号CN203861275U)、一种吸引活检钳套装(公开号CN204723104U)、一种新型活检钳(公开号CN207341776U)、一次性活检钳(公开号CN209332124U)等等。Biopsy forceps are an indispensable tool for removing diseased living tissue, and there are a large number of designs in the prior art. For example, Chinese patents: a cervical biopsy forceps (publication number CN203861275U), a suction biopsy forceps set (publication number CN204723104U), a new type of biopsy forceps (publication number CN207341776U), a disposable biopsy forceps (publication number CN209332124U), etc. .
近年来随着我国经济社会发展,各类肿瘤的发生率呈现逐年上升的趋势,在人体骨组织的原发性、转移性肿瘤、结核感染等也不断增加。在实际临床工作中,作为骨肿瘤、结核等疾病诊断的金标准是需要获取部分病变活体组织,进行病理组织检测明确诊断。而获取病变活体组织的方法目前主要有开放的手术切除取得和经皮穿刺取活检。经皮穿刺取活检术微创操作,对患者机体损伤小,是目前最常用的取活检方法。但是目前骨科活检工具单一,活检钳、活检穿刺针等因为采用直通取材方式,操作空间较为狭小,实际采集量偏小,效果并不理想,导致活检的结果阴性率高,检测结果往往不够准确,影响患者的诊断治疗。In recent years, with the development of my country's economy and society, the incidence of various types of tumors has been increasing year by year. In actual clinical work, as the gold standard for the diagnosis of bone tumors, tuberculosis and other diseases, it is necessary to obtain some diseased living tissues and conduct pathological tissue testing to confirm the diagnosis. The methods of obtaining the diseased living tissue currently mainly include open surgical excision and percutaneous biopsy. Percutaneous biopsy is a minimally invasive procedure with little damage to the patient's body, and is currently the most commonly used biopsy method. However, the current orthopaedic biopsy tools are single, biopsy forceps, biopsy needles, etc., because of the straight-through sampling method, the operating space is relatively small, the actual collection volume is small, and the effect is not ideal, resulting in a high negative rate of biopsy results, and the test results are often inaccurate. affect the diagnosis and treatment of patients.
因此,亟需全新的设计一种用于挖取活体组织的活检钳,能够提高活体组织的采集量,进而提高活检的准确性。Therefore, there is an urgent need for a new design of a biopsy forceps for excavating living tissue, which can increase the amount of living tissue collected, thereby improving the accuracy of biopsy.
发明内容SUMMARY OF THE INVENTION
本发明的发明目的在于:针对上述存在的问题,提供一种用于挖取活体组织的活检钳,本发明能够提高活体组织的采集量,提高活检检查结果的准确性。The purpose of the present invention is to provide a biopsy forceps for excavating living tissue in view of the above-mentioned problems. The present invention can increase the amount of living tissue collected and improve the accuracy of biopsy inspection results.
本发明采用的技术方案如下:The technical scheme adopted in the present invention is as follows:
一种用于挖取活体组织的活检钳,包括活检钳主体,所述活检钳主体的动杆可沿其定杆作前后运动,还包括设置于所述动杆的前端位置的挖刀,所述挖刀的前端具有可挖入患者机体的刀刃;当活检钳主体使动杆作向前运动时,所述动杆将驱动所述挖刀向前运动,挖刀作出挖取动作,用以挖取活体组织。A biopsy forceps for digging out living tissue, comprising a biopsy forceps main body, a movable rod of the biopsy forceps main body can move back and forth along its fixed rod, and a digging knife arranged at the front end of the movable rod, so The front end of the digging knife has a blade that can dig into the patient's body; when the main body of the biopsy forceps makes the moving rod move forward, the moving rod will drive the digging knife to move forward, and the digging knife makes a digging action to use Excavate living tissue.
本发明的活检钳,其活检钳主体的动杆可沿活检钳主体的定杆作前后运动,活检钳主体的具体结构可参照现有技术来设计。得益于动杆的前端位置设置的挖刀的设计,挖刀的前端具有可挖入患者机体的刀刃;当活检钳主体使动杆作向前运动时,动杆将驱动挖刀向前运动,通过挖刀的挖取动作实现在患者机体上挖取活体组织。相比现有技术的活检钳而言,现有的活检钳要么是通过钳夹式钳口的张合来夹取活体组织,要么是通过剪刀式的钳口来剪取活体组织,现有的活检钳在操作空间较大时,能够适用;但是在狭小的操作空间内,现有的活检钳就难以适用了,采集活体组织十分困难,即使能够采集到活体组织的量都是非常小的,严重影响活检检查结果的准确性。而本发明的活检钳,是通过挖刀的向前运动并作出的挖取动来实现活体组织的挖取,能够有效实现活体组织的采集,并提高活体组织的采集量,进而能够提高活检检查结果的准确性。In the biopsy forceps of the present invention, the movable rod of the biopsy forceps body can move back and forth along the fixed rod of the biopsy forceps body, and the specific structure of the biopsy forceps body can be designed with reference to the prior art. Thanks to the design of the digging knife set at the front end of the moving rod, the front end of the digging knife has a cutting edge that can dig into the patient's body; when the biopsy forceps body moves the moving rod forward, the moving rod will drive the digging knife to move forward , through the digging action of the digging knife to dig out the living tissue on the patient's body. Compared with the biopsy forceps in the prior art, the existing biopsy forceps either clamp the living tissue through the opening and closing of the jaws, or cut the living tissue through the jaws of the scissors. It can be applied when the operating space is large; however, in a narrow operating space, the existing biopsy forceps are difficult to apply, and it is very difficult to collect living tissue. Even if the amount of living tissue that can be collected is very small, it will seriously affect Accuracy of biopsy results. The biopsy forceps of the present invention realizes the digging of living tissue through the forward movement of the digging knife and the digging action, which can effectively realize the collection of living tissue and increase the collection amount of living tissue, thereby improving biopsy inspection. accuracy of results.
进一步的,所述挖刀采用可产生弹性形变的硬质材料制成,其自由状态下大致呈弧形状;所述定杆的前端长于所述动杆的前端。Further, the digging knife is made of a hard material that can produce elastic deformation, and is generally arc-shaped in a free state; the front end of the fixed rod is longer than the front end of the movable rod.
进一步的,当活检钳主体使动杆作向前运动时,所述动杆带动所述挖刀向前运动,挖刀将作伸出挖取动作,用以挖取活体组织,此时挖刀大致呈弧形状;当活检钳主体使动杆作向后运动时,所述动杆带动所述挖刀向后运动,挖刀将作缩回动作,此时挖刀将产生弹性形变并压在定杆的顶面前端位置。由于挖刀采用可产生弹性形变的硬质材料制成,其自由状态下大致呈弧形,并且定杆的前端长于动杆的前端。当挖刀作缩回动作时,挖刀能够产生弹性形变并压在定杆的顶面前端位置,以备下一次的伸出挖取动作。当挖刀作伸出挖取动作时,挖刀能够逐渐的恢复成大致呈弧形状,用以实现挖刀的伸出挖取动作。Further, when the main body of the biopsy forceps makes the moving rod move forward, the moving rod drives the digging knife to move forward, and the digging knife will perform a protruding digging action to dig out living tissue. At this time, the digging knife Roughly arc-shaped; when the main body of the biopsy forceps moves the moving rod backward, the moving rod drives the digging knife to move backward, the digging knife will retract, and the digging knife will be elastically deformed and pressed on the digging knife. The position of the front end of the top surface of the fixed rod. Since the digging knife is made of a hard material that can produce elastic deformation, it is roughly arc-shaped in a free state, and the front end of the fixed rod is longer than the front end of the movable rod. When the digging knife is retracted, the digging knife can be elastically deformed and pressed against the front end position of the top surface of the fixed rod, so as to prepare for the next extension and digging operation. When the digging knife performs a protruding digging action, the digging knife can gradually recover to a substantially arc shape, so as to realize the protruding and digging action of the digging knife.
优选的,所述定杆的顶面前端向上凸起有凸台。采用本设计时,当通过活检钳主体使动杆作向后运动,挖刀作缩回动作时,挖刀将产生弹性形变且压在定杆的凸台上。Preferably, the front end of the top surface of the fixed rod is protruded upward with a boss. When this design is adopted, when the moving rod is moved backward through the main body of the biopsy forceps and the digging knife is retracted, the digging knife will be elastically deformed and pressed on the boss of the fixed rod.
进一步的,所述挖刀的内弧壁处具有凹腔。凹腔能够容纳活体组织,以使挖刀能够可靠的挖取活体组织。Further, the inner arc wall of the digging knife has a concave cavity. The cavity can accommodate the living tissue, so that the digging knife can reliably dig the living tissue.
进一步的,所述挖刀的侧向具有刀刃。可以是挖刀的其中一侧具有刀刃,也可以是挖刀的两侧都具有刀刃。挖刀侧向刀刃称为侧刀刃。挖刀挖取活体组织的动作主要通过其前刀刃来实现,前刀刃能够切割活体组织的根部,有利于活体组织与患者机体相脱离。而侧刀刃的设计目的在于:当活检钳通过挖刀的前刀刃挖入患者机体,挖刀挖住欲采集的活体组织后,再通过活检钳使挖刀旋转时,挖刀的侧刀刃将切割活体组织的圆周方向,在挖刀的前刀刃、侧刀刃的切割作用下,直接使得活体组织与患者机体相脱离,以便于挖刀将活体组织可靠的挖取出。Further, the side of the digging knife has a cutting edge. One side of the digging knife may have a blade, or both sides of the digging knife may have a blade. The lateral cutting edge of the digger is called the side cutting edge. The action of digging out the living tissue is mainly realized by its front blade, and the front blade can cut the root of the living tissue, which is conducive to the separation of the living tissue from the patient's body. The design purpose of the side blade is: when the biopsy forceps digs into the patient's body through the front blade of the digger, after the digger digs the living tissue to be collected, and then rotates the digger through the biopsy forceps, the side blade of the digger will cut In the circumferential direction of the living tissue, under the cutting action of the front and side blades of the excavator, the living tissue is directly separated from the patient's body, so that the excavator can reliably dig out the living tissue.
进一步的,所述挖刀包括相连的刀身和刀柄,所述刀身大致呈弧形状,所述刀刃设置于所述刀身上。挖刀的刀身用以挖取活体组织,挖刀的刀柄连接活检钳的动杆。Further, the digging knife includes a connected blade body and a blade handle, the blade body is substantially arc-shaped, and the blade edge is disposed on the blade body. The blade of the digging knife is used to dig out the living tissue, and the handle of the digging knife is connected to the moving rod of the biopsy forceps.
可供选择的,所述挖刀与所述动杆为分体结构,且所述挖刀可拆卸的连接于所述动杆的前端位置。便于更换挖刀,能够实现一患一挖刀的目的。Optionally, the digging knife and the moving rod are of separate structures, and the digging knife is detachably connected to the front end of the moving rod. It is convenient to replace the digging knife, and the purpose of one digging knife can be realized.
可供选择的,所述挖刀与所述动杆为一体结构。即挖刀与动杆使不可拆卸的连接的,比如挖刀与动杆通过焊接方式相连,或者,挖刀与动杆是一体制成结构。Optionally, the digging knife and the moving rod are integral structures. That is, the digging knife and the movable rod are connected in a non-detachable manner, for example, the digging knife and the movable rod are connected by welding, or the digging knife and the movable rod are integrally formed into a structure.
可供选择的,所述定杆包括定杆本体以及可拆卸的连接于所述定杆本体的前端的端头。将便于更换端头,能够实现一患一端头的目的。Optionally, the fixed rod includes a fixed rod body and a detachable end connected to the front end of the fixed rod body. It will be convenient to replace the end, and the purpose of one end of the end can be achieved.
综上所述,由于采用了上述技术方案,本发明的有益效果是:To sum up, due to the adoption of the above-mentioned technical solutions, the beneficial effects of the present invention are:
本发明的一种用于挖取活体组织的活检钳,当活检钳主体使动杆作向前运动时,动杆将驱动挖刀向前运动,通过挖刀的挖取动作实现在患者机体上挖取活体组织。相比现有技术的活检钳而言,在狭小的操作空间内,现有的活检钳就难以适用了,采集活体组织十分困难,即使能够采集到活体组织的量都是非常小的,严重影响活检检查结果的准确性。而本发明的活检钳,是通过挖刀的向前运动并作出的挖取动来实现活体组织的挖取,能够有效实现活体组织的采集,并提高活体组织的采集量,进而能够提高活检检查结果的准确性。The biopsy forceps of the present invention is used for digging out living tissue. When the main body of the biopsy forceps makes the moving rod move forward, the moving rod will drive the digging knife to move forward, and the digging action of the digging knife is realized on the patient's body. Excavate living tissue. Compared with the biopsy forceps of the prior art, the existing biopsy forceps are difficult to apply in a narrow operating space, and it is very difficult to collect living tissue, even if the amount of living tissue that can be collected is very small, seriously affecting Accuracy of biopsy results. The biopsy forceps of the present invention realizes the digging of living tissue through the forward movement of the digging knife and the digging action, which can effectively realize the collection of living tissue and increase the collection amount of living tissue, thereby improving biopsy inspection. accuracy of results.
附图说明Description of drawings
本发明将通过例子并参照附图的方式说明,其中:The invention will be described by way of example and with reference to the accompanying drawings, in which:
图1是挖刀的结构示意图,其中,挖刀的前刀刃呈直线状;Fig. 1 is a structural schematic diagram of a digging knife, wherein the front blade of the digging knife is linear;
图2是挖刀的结构示意图,其中,挖刀的前刀刃呈圆弧状;Figure 2 is a schematic structural diagram of a digging knife, wherein the front blade of the digging knife is in an arc shape;
图3是挖刀的俯视图,其中,挖刀的前刀刃呈圆弧状;Figure 3 is a top view of a digging knife, wherein the front blade of the digging knife is in an arc shape;
图4是挖刀的仰视图,其中,挖刀的前刀刃呈直线状;Figure 4 is a bottom view of the digging knife, wherein the front blade of the digging knife is straight;
图5是挖刀的剖视图,其中,挖刀的刀身仅包括弧形刀段;Figure 5 is a cross-sectional view of a digging knife, wherein the blade body of the digging knife only includes an arc-shaped blade segment;
图6是挖刀的侧视图,其中,挖刀的刀身包括弧形刀段和直形刀段;Figure 6 is a side view of a digging knife, wherein the blade body of the digging knife includes an arc-shaped blade segment and a straight-shaped blade segment;
图7是活检钳主体的动杆与定杆的拆分结构示意图;7 is a schematic diagram of the split structure of the movable rod and the fixed rod of the biopsy forceps main body;
图8是活检钳主体的动杆与定杆的装配结构示意图;8 is a schematic diagram of the assembly structure of the movable rod and the fixed rod of the biopsy forceps main body;
图9是活检钳主体的动杆与定杆剖视图;9 is a cross-sectional view of the movable rod and the fixed rod of the biopsy forceps main body;
图10是第一种形式的挖刀与活检钳的拆分结构示意图,其中,动杆的前端位置的接口为插入槽,挖刀的刀柄上开设有连接孔;10 is a schematic view of the split structure of the first form of the digging knife and the biopsy forceps, wherein, the interface at the front end of the moving rod is an insertion slot, and the shank of the digging knife is provided with a connecting hole;
图11是第二种形式的挖刀与活检钳的拆分结构示意图,其中,动杆的前端位置的接口为插入槽,挖刀的刀柄上没有连接孔;11 is a schematic diagram of the split structure of the second form of the digging knife and the biopsy forceps, wherein the interface at the front end of the moving rod is an insertion slot, and there is no connection hole on the handle of the digging knife;
图12是第三种形式的挖刀与活检钳的拆分结构示意图,其中,动杆的前端位置的接口为安放槽,挖刀的刀柄呈阶梯状;12 is a schematic diagram of the split structure of the third type of digging knife and biopsy forceps, wherein the interface at the front end of the moving rod is a placement groove, and the handle of the digging knife is stepped;
图13是第四种形式的挖刀与活检钳的拆分结构示意图,其中,动杆的前端位置的接口为安放槽,挖刀的刀柄呈平板状;Figure 13 is a schematic diagram of the split structure of the fourth form of the digging knife and the biopsy forceps, wherein the interface at the front end of the moving rod is a placement groove, and the handle of the digging knife is in the shape of a flat plate;
图14是活检钳的挖刀、动杆与定杆的结构示意图,其中,动杆已沿定杆向前运动,挖刀伸出呈弧形状,可挖取活体组织;Figure 14 is a schematic diagram of the structure of the digging knife, the moving rod and the fixed rod of the biopsy forceps, wherein the moving rod has moved forward along the fixed rod, and the digging knife is extended in an arc shape, which can dig out living tissue;
图15是活检钳的挖刀、动杆与定杆的结构示意图,其中,动杆已沿定杆向后运动,挖刀缩回,挖刀产生弹性形变且压在定杆的凸台上;15 is a schematic structural diagram of the digging knife, the movable rod and the fixed rod of the biopsy forceps, wherein the movable rod has moved backward along the fixed rod, the digging knife is retracted, and the digging knife is elastically deformed and pressed on the boss of the fixed rod;
图16是活检钳的侧视图,其中,动杆已沿定杆向前运动,挖刀伸出呈弧形状,可挖取活体组织。Fig. 16 is a side view of the biopsy forceps, wherein the movable rod has moved forward along the fixed rod, and the digging knife extends in an arc shape, which can dig out living tissue.
图17是活检钳的侧视图,其中,动杆已沿定杆向后运动,挖刀缩回,挖刀产生弹性形变且压在定杆的凸台上;Figure 17 is a side view of the biopsy forceps, wherein the moving rod has moved backwards along the fixed rod, the digging knife is retracted, and the digging knife is elastically deformed and pressed on the boss of the fixed rod;
图18是环锯旋转切割患者机体的病变活体组织的示意图;Figure 18 is a schematic diagram of a trephine rotary cutting a diseased living tissue of a patient's body;
图19是缩回状态的活检钳插入套管内,挖刀的前刀刃大致对环隙的示意图;19 is a schematic view of the retracted biopsy forceps inserted into the cannula, and the front blade of the digging knife roughly facing the annular gap;
图20是挖取状态的活检钳的挖刀挖入活体组织的根部位置的示意图;Figure 20 is a schematic diagram of the position of the root of the biopsy forceps in the digging state where the digging knife digs into the living tissue;
图21是第一种活检钳将活体组织挖取出的示意图,其中,活体组织未被挖刀的侧刀刃切割;Figure 21 is a schematic diagram of the first biopsy forceps digging out the living tissue, wherein the living tissue is not cut by the side blade of the digging knife;
图22是第二种活检钳将活体组织挖取出的示意图,其中,活体组织已被挖刀的侧刀刃切割。Fig. 22 is a schematic diagram of the second type of biopsy forceps digging out the living tissue, wherein the living tissue has been cut by the side cutting edge of the digging knife.
图中标记:1-挖刀,11-刀身,11a-弧形刀段,11b-直形刀段,111-前刀刃,112-侧刀刃,113-凹腔,12-刀柄,12a-后柄段,12b-前柄段,121-连接孔,122-盖板;2-动杆,21-插入槽,22-安放槽,23-导向轨;3-定杆,31-定杆本体,311-导向槽,32-端头,321-凸台,322-斜面;4-套管;5-环锯;6环隙。Marking in the picture: 1-digging knife, 11-blade body, 11a-arc-shaped blade section, 11b-straight blade section, 111-front blade, 112-side blade, 113-cavity, 12-handle, 12a-back Handle section, 12b-front handle section, 121-connection hole, 122-cover plate; 2-moving rod, 21-insertion slot, 22-placement slot, 23-guide rail; 3-fixed rod, 31-fixed rod body, 311-Guide groove, 32-End, 321-Boss, 322-Bevel; 4-Sleeve; 5-Trip saw; 6-Annular gap.
具体实施方式Detailed ways
本说明书中公开的所有特征,或公开的所有方法或过程中的步骤,除了互相排斥的特征和/或步骤以外,均可以以任何方式组合。All features disclosed in this specification, or all disclosed steps in a method or process, may be combined in any way except mutually exclusive features and/or steps.
本说明书中公开的任一特征,除非特别叙述,均可被其他等效或具有类似目的的替代特征加以替换。即,除非特别叙述,每个特征只是一系列等效或类似特征中的一个例子而已。Any feature disclosed in this specification, unless expressly stated otherwise, may be replaced by other equivalent or alternative features serving a similar purpose. That is, unless expressly stated otherwise, each feature is but one example of a series of equivalent or similar features.
实施例一Example 1
如图1至图17所示,本实施例的一种用于挖取活体组织的活检钳,包括活检钳主体,所述活检钳主体的动杆2可沿其定杆3作前后运动,还包括设置于所述动杆2的前端位置的挖刀1,所述挖刀1的前端具有可挖入患者机体的刀刃;当活检钳主体使动杆2作向前运动时,所述动杆2将驱动所述挖刀1向前运动,挖刀1作出挖取动作,用以挖取活体组织。As shown in FIGS. 1 to 17 , a biopsy forceps for digging out living tissue in this embodiment includes a biopsy forceps main body, and a
本发明的活检钳,其活检钳主体的动杆2可沿活检钳主体的定杆3作前后运动,活检钳主体的具体结构可参照现有技术来设计。得益于动杆2的前端位置设置的挖刀1的设计,挖刀1的前端具有可挖入患者机体的刀刃;当活检钳主体使动杆2作向前运动时,动杆2将驱动挖刀1向前运动,通过挖刀1的挖取动作实现在患者机体上挖取活体组织。相比现有技术的活检钳而言,现有的活检钳要么是通过钳夹式钳口的张合来夹取活体组织,要么是通过剪刀式的钳口来剪取活体组织,现有的活检钳在操作空间较大时,能够适用;但是在狭小的操作空间内,现有的活检钳就难以适用了,采集活体组织十分困难,即使能够采集到活体组织的量都是非常小的,严重影响活检检查结果的准确性。而本发明的活检钳,是通过挖刀1的向前运动并作出的挖取动来实现活体组织的挖取,能够有效实现活体组织的采集,并提高活体组织的采集量,进而能够提高活检检查结果的准确性。In the biopsy forceps of the present invention, the
进一步的,如图1至图6所示,所述挖刀1采用可产生弹性形变的硬质材料制成,其自由状态下大致呈弧形状;所述定杆3的前端长于所述动杆2的前端。在狭小的操作空间内,便于活检嵌的定杆3驱动挖刀1执行挖取活体组织的动作。Further, as shown in FIG. 1 to FIG. 6 , the digging
进一步的,当活检钳主体使动杆2作向前运动时,所述动杆2带动所述挖刀1向前运动,挖刀1将作伸出挖取动作,用以挖取活体组织,此时挖刀1大致呈弧形状,如图14、图16所示;当活检钳主体使动杆2作向后运动时,所述动杆2带动所述挖刀1向后运动,挖刀1将作缩回动作,此时挖刀1将产生弹性形变并压在定杆3的顶面前端位置,如图15、图17所示。由于挖刀1采用可产生弹性形变的硬质材料制成,其自由状态下大致呈弧形,并且定杆3的前端长于动杆2的前端。当挖刀1作缩回动作时,挖刀1能够产生弹性形变并压在定杆3的顶面前端位置,以备下一次的伸出挖取动作。当挖刀1作伸出挖取动作时,挖刀1能够逐渐的恢复成大致呈弧形状,用以实现挖刀1的伸出挖取动作。Further, when the main body of the biopsy forceps makes the moving
进一步的,如图2所示,所述挖刀1的内弧壁处具有凹腔113。凹腔113能够容纳活体组织,以使挖刀1能够可靠的挖取活体组织。Further, as shown in FIG. 2 , a
可供选择的,所述挖刀1前端的刀刃呈直线状或圆弧状。即,可以是,挖刀1的前刀刃111呈直线状,如图1、图4所示;或者,挖刀1的前刀刃111呈圆弧状,如图2、图3所示。Optionally, the cutting edge at the front end of the digging
进一步的,如图1至图4所示,所述挖刀1的侧向具有刀刃。可以是挖刀1的其中一侧具有刀刃,也可以是挖刀1的两侧都具有刀刃。挖刀1侧向刀刃称为侧刀刃112。挖刀1挖取活体组织的动作主要通过其前刀刃111来实现,前刀刃111能够切割活体组织的根部,有利于活体组织与患者机体相脱离。而侧刀刃112的设计目的在于:当活检钳通过挖刀1的前刀刃111挖入患者机体,挖刀1挖住欲采集的活体组织后,再通过活检钳使挖刀1旋转时,挖刀1的侧刀刃112将切割活体组织的圆周方向,在挖刀1的前刀刃111、侧刀刃112的切割作用下,直接使得活体组织与患者机体相脱离,以便于挖刀1将活体组织可靠的挖取出。当然,挖刀1也可以仅具有前刀刃111,而不具有侧刀刃112的设计,依然能够实现挖刀1将活体组织挖取出的目的。Further, as shown in FIG. 1 to FIG. 4 , the side of the digging
进一步的,如图1至图6所示,所述挖刀1包括相连的刀身11和刀柄12,所述刀身11大致呈弧形状,所述刀刃设置于所述刀身11上。挖刀1的刀身11用以挖取活体组织,挖刀1的刀柄12用于连接活检钳的动杆2。结合挖刀1采用可产生弹性形变的硬质材料制成设计时,具体的,是挖刀1的刀身11可产生弹性形变,其在自由状态下大致呈弧形状。例如,所述挖刀1采用医用不锈钢制成,挖刀的刀身11的壁厚为0.5mm-1mm,可产生弹性形变。结合前刀刃111、侧刀刃112的设计时,前刀刃111设置于刀身11的前端,侧刀刃112设置于刀身11的侧向。进一步的,如图5、图6所示,所述刀身11的壁厚从后端至前端平滑的递减。能够降低挖刀1挖取活体组织时的阻力,有利于挖刀1挖取活体组织。Further, as shown in FIG. 1 to FIG. 6 , the digging
如图6所示,所述刀身11包括相连的弧形刀段11a和直形刀段11b,所述弧形刀段11a呈弧形状,所述直形刀段11b连接于所述弧形刀段11a与所述刀柄12之间。当然,如图5所示,刀身11仅包括弧形刀段11a也是可行的。刀身11包括相连的弧形刀段11a和直形刀段11b的设计目的在于,直形刀段11b能够增加挖刀1的挖取深度。结合刀身11的壁厚从后端至前端平滑的递减的设计时,优选的,是刀身11的弧形刀段11a的壁厚从后端至前端平滑的递减。如图5、图6所示,所述刀柄12呈阶梯状,其包括相连的后柄段12a和前柄段12b,所述前柄段12b的壁厚大于所述后柄段12a的壁厚,所述前柄段12b连接于所述刀身11与所述后柄段12a之间。便于刀柄12可拆卸的定位安装到活检钳上。当然也可以是,刀柄12呈平板状(比如刀柄12仅包括前柄段12b)。如图1至图4所示,所述刀柄12上开设有连接孔121。结合刀柄12包括后柄段12a和前柄段12b的设计时,连接孔121开设于后柄段12a上。As shown in FIG. 6 , the
挖刀1与动杆2可以是可拆卸的分体结构,也可以是不可拆卸的一体结构,具体的如下所述。The digging
可供选择的,如图10至图13所示,所述挖刀1与所述动杆2为分体结构,且所述挖刀1可拆卸的连接于所述动杆2的前端位置。便于更换挖刀1,能够实现一患一挖刀的目的。在所述动杆2的前端位置设置有用于可拆卸连接挖刀的接口,以便于将挖刀1可拆卸的安装于动杆2前端位置的接口上,再通过紧固件(如螺栓)使挖刀1与动杆2固定相连形成活检钳。Alternatively, as shown in FIGS. 10 to 13 , the digging
如图7、图10、图11所示,所述接口为开设于所述动杆2的前端面的插入槽21。挖刀1能够插入于插入槽21内,再通过螺栓可使挖刀11可拆卸的安装于动杆2的前端位置。在其中一实施例中,如图10所示,所述动杆的顶面开设有贯穿至插入槽21的圆孔,插入槽21的底面开设有对应于圆孔的螺纹孔,挖刀1的刀柄12上开设有连接孔121,当挖刀1的刀柄12插入槽21内后,螺栓依次穿过圆孔、连接孔121后与螺纹孔相旋合,可实现挖刀1与动杆2固定。在另一实施例中,如图11所示,所述动杆的顶面开设有贯穿至插入槽21的螺纹孔,挖刀1的刀柄12上没有连接孔,当挖刀1的刀柄12插入槽21内后,螺栓旋合入螺纹孔后可顶紧挖刀1,可实现挖刀1与动杆2固定。As shown in FIG. 7 , FIG. 10 , and FIG. 11 , the interface is an
如图8、图9、图12、图13所示,所述接口为开设于所述动杆2的顶面且延伸至前端面的安放槽22。挖刀1能够安放于安放槽22上,再通过螺栓可使挖刀1可拆卸的安装于动杆2的前端位置。在其中一实施例中,如图12所示,安放槽的底面开设有螺纹孔,挖刀1的刀柄12呈阶梯状,包括后柄段12a和前柄段12b,后柄段12a上开设有连接孔121,当挖刀1的刀柄12安放于安放槽22上后,在后柄段12a上盖上一盖板122,盖板122上开设有圆孔,螺栓依次穿过圆孔、连接孔121后与螺纹孔相旋合,可实现挖刀1与动杆2固定。在另一实施例中,如图13所示,安放槽的底面开设有螺纹孔,挖刀1的刀柄12呈平板,刀柄12上开设有连接孔121,当挖刀1的刀柄12安放于安放槽22上后,螺栓穿过连接孔121后与螺纹孔相旋合,可实现挖刀1与动杆2固定。无论是接口为插入槽21还是安放槽22的设计,都可实现挖刀1可拆卸的安装于动杆2的前端位置,实现挖刀1与动杆2的固定连接。As shown in FIG. 8 , FIG. 9 , FIG. 12 , and FIG. 13 , the interface is a mounting
可供选择的,所述挖刀1与所述动杆2为一体结构。即挖刀1与动杆2使不可拆卸的连接的,比如挖刀1与动杆2通过焊接方式相连,或者,挖刀1与动杆2是一体制成结构。Optionally, the digging
总之,挖刀1与动杆2为分体结构或者为一体结构都是可行的。相比而言,挖刀1与动杆2为分体结构时更佳优选的设计。In a word, it is feasible that the
可供选择的,如图7至图9、图14、图15所示,所述定杆3的顶面前端向上凸起有凸台321。采用本设计时,当通过活检钳主体使动杆2作向后运动,挖刀1作缩回动作时,挖刀将产生弹性形变且压在定杆3的凸台321上,如图15所示。具体的,所述凸台321与所述动杆2相正对。如果不采用凸台321的设计,挖刀1作缩回动作时,挖刀1将产生弹性形变且压在定杆3的顶面前端位置。相比而言,采用凸台321的设计是优选的设计,能够挖取的活体组织的量相对更多一些。Alternatively, as shown in FIGS. 7 to 9 , 14 and 15 , the front end of the top surface of the fixed
如图9所示,所述凸台321的顶面低于所述动杆2的顶面。当通过活检钳主体使动杆2作向后运动,挖刀1作缩回动作时,有利于使得挖刀产生弹性形变且压在定杆3的凸台321上,能够实现挖刀不超出动杆2顶面的目的。如果凸台321的顶面不低于动杆2的顶面,那么挖刀作缩回动作后,挖刀将超出动杆2的顶面。As shown in FIG. 9 , the top surface of the
如图7至图9,所示所述凸台321的顶部具有倾斜至凸台前端面的斜面322。当通过活检钳主体使动杆2作向后运动时,挖刀作缩回动作时,挖刀将沿斜面322缩回,有利于挖刀产生弹性形变且压在定杆3的凸台321上。As shown in FIG. 7 to FIG. 9 , the top of the
可供选择的,如图7至图9所示,所述定杆3包括定杆本体31以及可拆卸的连接于所述定杆本体31的前端的端头32。动杆2可沿定杆3的定杆本体31作前后运动。结合凸台321的设计时,凸台321设置于端头32上。端头32能够可拆卸的连接于定杆本体31的前端,将便于更换端头32,能够实现一患一端头的目的。进一步的,如图7至图9所示,所述端头32通过螺栓可拆卸的连接于所述定杆本体31的前端;或者,所述端头32通过螺纹连接方式可拆卸的连接于所述定杆本体31的前端。在其中一实施例中,如图7所示,端头32通过螺栓可拆卸的连接于定杆本体31的前端。在另一实施例中,如图8、图9所示,端头32通过螺纹连接方式可拆卸的连接于定杆本体31的前端。都能够实现端头32可拆卸的连接于定杆本体31前端的目的。Alternatively, as shown in FIG. 7 to FIG. 9 , the fixed
进一步的,如图7至图9所示,所述端头32通过螺栓可拆卸的连接于所述定杆本体31的前端;或者,所述端头32通过螺纹连接方式可拆卸的连接于所述定杆本体31的前端。都能够实现端头32可拆卸的连接于定杆本体31前端的目的。在其中一实施例中,如图7所示,端头32通过螺栓可拆卸的连接于定杆本体31的前端。在另一实施例中,如图8、图9所示,端头32通过螺纹连接方式可拆卸的连接于定杆本体31的前端。Further, as shown in FIGS. 7 to 9 , the
挖刀1可拆卸的连接于动杆2的前端位置,以及端头32可拆卸的连接于定杆本体31的前端的设计相结合时,可使得挖刀1、端头32不重复利用,避免出现交叉感染的风险。When the design that the digging
可供选择的,如图7至图9所示,所述动杆2的底部设置有导向轨23,所述定杆3的顶部设置有导向槽311,所述导向轨23滑动的嵌入所述导向311槽内。能够在动杆2沿定杆3作前后运动时起到导向作用,提高动杆2运动的可靠性。Alternatively, as shown in FIG. 7 to FIG. 9 , the bottom of the
实施例二
基于实施例一的设计基础上,本实施例具体的介绍如何采用实施例一的活检钳在患者机体上挖取活体组织。Based on the design of the first embodiment, this embodiment specifically introduces how to use the biopsy forceps of the first embodiment to dig out the living tissue from the patient's body.
以最常见的脊柱病灶穿刺活检术为例,手术前根据脊柱CT扫描结果确定病变椎体经椎弓根穿刺的穿刺点、冠状位和矢状位的穿刺角度、穿刺点皮肤距离病变椎体棘突中点的距离等参数。手术准备完毕后,患者俯卧位于手术床上后,先用C臂X光机确定病变椎体,消毒铺巾后根据术前测量参数准确地将穿刺引导针插入病变部位,然后在C臂X光机监视下继续进行执行以下步骤:Taking the most common puncture biopsy of spinal lesions as an example, the puncture point, coronal and sagittal puncture angles, and the distance from the skin of the puncture point to the spine of the diseased vertebral body were determined according to the results of spinal CT scan before the operation. Parameters such as the distance from the midpoint of the protrusion. After the preparation for surgery, the patient lies prone on the operating bed, and the C-arm X-ray machine is used to determine the diseased vertebral body. Proceed to perform the following steps under monitoring:
S1、将套管4安放到带挖取活体组织的位置,再将环锯5插入套管4内并旋转锯割骨组织的病灶部位(即,患者机体的病变活体组织),如图18所示。环锯5将待挖取的活体组织锯割适当深度后,将环锯5拔出,此时,除了活体组织根部外,活体组织与患者机体相分离,活体组织与患者机体存在由环锯5形成的呈环状的环隙6。S1, place the
S2、将处于缩回状态的活检钳插入套管4内,并使挖刀1的前刀刃111对准环隙6,如图19所示;S2. Insert the biopsy forceps in the retracted state into the
S3、通过活检钳主体使动杆2作向前运动,动杆2带动挖刀1向前运动,挖刀1挖入患者机体,挖刀1逐渐的恢复成大致呈弧形状,并挖至活体组织的根部位置,使得活体组织被夹持在挖刀1与定杆3的前端之间,便于将活体组织挖取出,如图20所示;S3. The moving
S4、将活检钳沿套管4拔出,完成挖取活体组织的挖取动作,挖取出的活体组织位于挖刀1与定杆3的前端之间,如图21所示。S4. Pull out the biopsy forceps along the
在进行S3中,挖刀1挖至活体组织的根部位置后,可通过旋转活检钳主体使挖刀1旋转,挖刀1的侧刀刃112将切割活体组织的圆周方向,挖取出的活体组织位于挖刀1与定杆3的前端之间,如图22所示。In S3, after the
如果不采用本发明的活检钳,而采用现有的钳夹式钳口或剪刀式钳口的现有活体组织,那么将难以实现采集活检组织的动作,因为为了实现活检术的微创操作,选取的套管4、环锯5的规格是较小的,例如套管4的内径约5mm,环锯5内径约4mm、壁厚约0.5mm(形成的环隙6的内径约4mm,宽度约0.5mm),在如此狭小的操作空间内,现有的活检钳难以施展张合的动作来夹取或剪取活体组织,并且骨组织的表面是较为坚硬,现有的活检钳又利用不了环隙6,更加增加了现有活检钳采集活体组织的难度。而采用本发明时,是通过挖刀的向前运动并作出的挖取动来实现活体组织的挖取,挖刀能够很方便的从环隙6处挖入患者机体,挖刀经环隙6穿过坚硬的骨组织表面,挖入松软的骨组织内部,非常的方便易行。If the biopsy forceps of the present invention is not used, but the existing living tissue of the existing clamp-type jaws or scissors-type jaws is used, it will be difficult to realize the action of collecting the biopsy tissue, because in order to realize the minimally invasive operation of the biopsy, The specifications of the selected
综上所述,采用本发明的一种用于挖取活体组织的活检钳,当活检钳主体使动杆作向前运动时,动杆将驱动挖刀向前运动,通过挖刀实现挖取活体组织的挖取动作,特别是在狭小的操作空间内,本发明的活检钳操作方便,能够采集更多量的活体组织,提高活检的准确性,有利于患者的诊断治疗。To sum up, using a biopsy forceps of the present invention for digging out living tissue, when the main body of the biopsy forceps moves the moving rod forward, the moving rod will drive the digging knife to move forward, and the digging knife is used to realize the digging. The digging action of living tissue, especially in a narrow operating space, the biopsy forceps of the present invention is convenient to operate, can collect a larger amount of living tissue, improves the accuracy of biopsy, and is beneficial to the diagnosis and treatment of patients.
本发明并不局限于前述的具体实施方式。本发明扩展到任何在本说明书中披露的新特征或任何新的组合,以及披露的任一新的方法或过程的步骤或任何新的组合。The present invention is not limited to the foregoing specific embodiments. The present invention extends to any new features or any new combination disclosed in this specification, as well as any new method or process steps or any new combination disclosed.
Claims (10)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010722101.5A CN111887905A (en) | 2020-07-24 | 2020-07-24 | Biopsy forceps for digging living tissue |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010722101.5A CN111887905A (en) | 2020-07-24 | 2020-07-24 | Biopsy forceps for digging living tissue |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111887905A true CN111887905A (en) | 2020-11-06 |
Family
ID=73189963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010722101.5A Pending CN111887905A (en) | 2020-07-24 | 2020-07-24 | Biopsy forceps for digging living tissue |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111887905A (en) |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5601572A (en) * | 1989-08-16 | 1997-02-11 | Raychem Corporation | Device or apparatus for manipulating matter having a elastic ring clip |
| US5797938A (en) * | 1995-10-20 | 1998-08-25 | Ethicon Endo-Surgery, Inc. | Self protecting knife for curved jaw surgical instruments |
| US5913866A (en) * | 1997-06-19 | 1999-06-22 | Cardiothoracic Systems, Inc. | Devices and methods for harvesting vascular conduits |
| US20100185116A1 (en) * | 2009-01-19 | 2010-07-22 | King Saud University | Punch biopsy device |
| US20120046682A1 (en) * | 2009-09-24 | 2012-02-23 | Medicinelodge, Inc. Dba Imds Co-Innovation | Reciprocating surgical instruments |
| CN104254284A (en) * | 2012-08-13 | 2014-12-31 | 奥林巴斯医疗株式会社 | Endoscope Treatment Instruments |
| CN209332124U (en) * | 2018-12-21 | 2019-09-03 | 张亚美 | Disposable biopsy forceps |
| CN213722135U (en) * | 2020-07-24 | 2021-07-20 | 梁静萍 | Biopsy forceps main body and biopsy forceps thereof |
| CN214231395U (en) * | 2020-07-24 | 2021-09-21 | 梁静萍 | Digging cutter for biopsy forceps and biopsy forceps thereof |
-
2020
- 2020-07-24 CN CN202010722101.5A patent/CN111887905A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5601572A (en) * | 1989-08-16 | 1997-02-11 | Raychem Corporation | Device or apparatus for manipulating matter having a elastic ring clip |
| US5797938A (en) * | 1995-10-20 | 1998-08-25 | Ethicon Endo-Surgery, Inc. | Self protecting knife for curved jaw surgical instruments |
| US5913866A (en) * | 1997-06-19 | 1999-06-22 | Cardiothoracic Systems, Inc. | Devices and methods for harvesting vascular conduits |
| US20100185116A1 (en) * | 2009-01-19 | 2010-07-22 | King Saud University | Punch biopsy device |
| US20120046682A1 (en) * | 2009-09-24 | 2012-02-23 | Medicinelodge, Inc. Dba Imds Co-Innovation | Reciprocating surgical instruments |
| CN104254284A (en) * | 2012-08-13 | 2014-12-31 | 奥林巴斯医疗株式会社 | Endoscope Treatment Instruments |
| CN209332124U (en) * | 2018-12-21 | 2019-09-03 | 张亚美 | Disposable biopsy forceps |
| CN213722135U (en) * | 2020-07-24 | 2021-07-20 | 梁静萍 | Biopsy forceps main body and biopsy forceps thereof |
| CN214231395U (en) * | 2020-07-24 | 2021-09-21 | 梁静萍 | Digging cutter for biopsy forceps and biopsy forceps thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4510053B2 (en) | Tissue cutting device | |
| JP3845023B2 (en) | Incisional biopsy device and method | |
| EP1676533B1 (en) | Method of manufacturing a needle assembly for use with a biopsy device | |
| JP2012517290A (en) | Apparatus and method for accessing a body part | |
| CN214231395U (en) | Digging cutter for biopsy forceps and biopsy forceps thereof | |
| CN213722135U (en) | Biopsy forceps main body and biopsy forceps thereof | |
| CN217162220U (en) | Minimally invasive biopsy cutter | |
| CN111887905A (en) | Biopsy forceps for digging living tissue | |
| CN219578919U (en) | Cut type myocardial biopsy device | |
| CN209377627U (en) | Negative pressure flexible puncture biopsy needle | |
| KR102659966B1 (en) | Cervical biopsy forceps | |
| CN201939391U (en) | Negative pressure trepan for skin biopsy | |
| CN219070420U (en) | A minimally invasive living body sampler for tumors | |
| CN212592226U (en) | Focus sampling device for medical oncology | |
| CN223601480U (en) | Vertebral body puncture biopsy needle | |
| CN215899741U (en) | Skin disease diagnosis sampling device | |
| CN209464017U (en) | A kind of mouth neoplasm collection of specimens pincers | |
| WO2025144097A1 (en) | Tissue biopsy instrument and method of forming the same | |
| CA2413861C (en) | Excisional biopsy devices and methods | |
| CN110710994A (en) | Tissue sampler |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20201106 |