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CN111801568A - 测定血小板浓度的方法及系统 - Google Patents

测定血小板浓度的方法及系统 Download PDF

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CN111801568A
CN111801568A CN201980011879.0A CN201980011879A CN111801568A CN 111801568 A CN111801568 A CN 111801568A CN 201980011879 A CN201980011879 A CN 201980011879A CN 111801568 A CN111801568 A CN 111801568A
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suspension
platelet
blood sample
analyzing
concentration
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CN111801568B (zh
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祁欢
叶波
郑文波
胡长松
郁琦
李朝阳
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06—Investigating concentration of particle suspensions
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    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
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Abstract

一种分析血液样本中血小板浓度的方法、血液分析系统(100)及存储介质，测定血液样本中血小板浓度的方法包括：将血液样本的第一份与稀释液混合，形成第一悬浮液；将血液样本的第二份与溶血剂和荧光染料混合以溶解红细胞和染色白细胞，形成第二悬浮液；测量第一悬浮液流过小孔的直流阻抗信号；测量第二悬浮液流过光学流动室(20)的光散射信号和荧光信号；分析第一悬浮液的该直流阻抗信号以获取第一血小板分布；分析第二悬浮液的光散射信号和荧光信号以区分血小板和白细胞并获取第二血小板分布；基于第一血小板分布和第二血小板分布确定血液样本的血小板分析数据，如血小板浓度。

Description

PCT国内申请，说明书已公开。

Claims (69)

  1. PCT国内申请，权利要求书已公开。
CN201980011879.0A 2018-04-28 2019-04-26 测定血小板浓度的方法及系统 Active CN111801568B (zh)

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CN111801568B (zh) * 2018-04-28 2024-05-24 深圳迈瑞生物医疗电子股份有限公司 测定血小板浓度的方法及系统
WO2021133686A1 (en) 2019-12-27 2021-07-01 Beckman Coulter, Inc. Sample preparation instrument
CN111337392A (zh) * 2020-02-28 2020-06-26 清华大学深圳国际研究生院 一种悬浮颗粒偏振荧光同步测量装置
WO2023010447A1 (zh) * 2021-08-05 2023-02-09 深圳迈瑞动物医疗科技股份有限公司 一种样本分析装置、动物用分析装置和样本分析方法
CN116952805A (zh) 2022-04-14 2023-10-27 深圳迈瑞生物医疗电子股份有限公司 样本分析仪以及血小板计数方法
CN116047045A (zh) * 2022-09-19 2023-05-02 中山市创艺生化工程有限公司 一种血细胞分析仪的血小板曲线拟合方法
JP2025093866A (ja) * 2023-11-08 2025-06-24 フェンウォール、インコーポレイテッド 流体中の細胞濃度および／または血小板質量指数の測定

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Publication number Priority date Publication date Assignee Title
CN114047109A (zh) * 2022-01-11 2022-02-15 深圳市帝迈生物技术有限公司 一种样本分析仪及其计数方法
CN114047109B (zh) * 2022-01-11 2022-06-21 深圳市帝迈生物技术有限公司 一种样本分析仪及其计数方法

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EP3789751B1 (en) 2024-06-26
WO2019206313A1 (zh) 2019-10-31
US20240230621A9 (en) 2024-07-11
EP3789751C0 (en) 2024-06-26
US12287319B2 (en) 2025-04-29
EP4439582C0 (en) 2025-10-22
US20240133864A1 (en) 2024-04-25
EP3789751A4 (en) 2021-06-30
EP4439582A3 (en) 2024-10-16
EP3789751A1 (en) 2021-03-10
EP4439582B1 (en) 2025-10-22
US11841358B2 (en) 2023-12-12
EP4439582A2 (en) 2024-10-02
US20210033593A1 (en) 2021-02-04

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