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CN111532108A - New uses of estratetraene - Google Patents

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CN111532108A
CN111532108A CN202010396057.3A CN202010396057A CN111532108A CN 111532108 A CN111532108 A CN 111532108A CN 202010396057 A CN202010396057 A CN 202010396057A CN 111532108 A CN111532108 A CN 111532108A
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driver
estratetraene
driving
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driving safety
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葛燕
瞿炜娜
王宇宸
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Institute of Psychology of CAS
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B60VEHICLES IN GENERAL
    • B60HARRANGEMENTS OF HEATING, COOLING, VENTILATING OR OTHER AIR-TREATING DEVICES SPECIALLY ADAPTED FOR PASSENGER OR GOODS SPACES OF VEHICLES
    • B60H3/00Other air-treating devices
    • B60H3/0007Adding substances other than water to the air, e.g. perfume, oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M21/02Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis for inducing sleep or relaxation, e.g. by direct nerve stimulation, hypnosis, analgesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0016Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the smell sense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0077Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus with application of chemical or pharmacological stimulus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0083Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus especially for waking up

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  • Traffic Control Systems (AREA)

Abstract

The invention discloses a new application of estratetraene, which is used for improving the driving safety of a driver. The invention discovers for the first time that the estratetraene solution improves the safety margin of a driver in driving behaviors in a subthreshold mode and reduces the negative influence caused by suprathreshold olfactory stimulation.

Description

雌甾四烯的新用途New uses of estratetraene

技术领域technical field

本发明涉及车辆安全驾驶领域,更具体地,涉及雌甾四烯的新用途。The present invention relates to the field of safe driving of vehicles, more particularly, to a new use of estratetraene.

背景技术Background technique

随着交通运输业的不断发展,交通事故也逐渐成为造成人员伤亡以及财产损失的一大重要因素。我国交通事故统计结果表明,由驾驶员的因素导致的事故占交通事故的74%,驾驶员的人误操作成为引起交通事故的主要原因。With the continuous development of the transportation industry, traffic accidents have gradually become an important factor causing casualties and property losses. The statistical results of traffic accidents in my country show that the accidents caused by drivers account for 74% of the traffic accidents, and the driver's human misoperation has become the main cause of traffic accidents.

驾驶员的车距控制能力可以通过TTC指标进行判断,某一时刻的TTC(time tocollision)是两车在该时刻的距离除以在该时刻速度差的绝对值。TTC不同于简单的车速判断,而是综合性的指标,能够真实地反应驾驶员的驾驶安全性,反应驾驶员的车距控制能力。TTC的值越大,表明驾驶员的驾驶安全性越好,车距控制能力越强。The driver's ability to control the distance between vehicles can be judged by the TTC indicator. The TTC (time tocollision) at a certain moment is the absolute value of the distance between the two vehicles at that moment divided by the speed difference at that moment. Different from simple speed judgment, TTC is a comprehensive indicator, which can truly reflect the driver's driving safety and the driver's ability to control the distance between vehicles. The larger the value of TTC, the better the driver's driving safety and the stronger the distance control ability.

许多研究者和有关人员希望通过对驾驶员的感官进行干预的方式,减少驾驶员的人误,从而提升驾驶安全性。例如在听觉领域,有研究者发现音乐的节奏可能对驾驶绩效产生影响;在嗅觉领域,有研究者通过薄荷、柠檬、葡萄果香等气味调节驾驶员的唤醒度和情绪,从而改善驾驶员的驾驶安全性。Many researchers and related personnel hope to reduce the driver's human error by intervening on the driver's senses, thereby improving the driving safety. For example, in the field of hearing, some researchers have found that the rhythm of music may have an impact on driving performance; in the field of smell, some researchers have adjusted the driver's arousal and mood through the smell of mint, lemon, grape fruit, etc., so as to improve the driver's performance. driving safety.

中国专利:一种用于缓解驾驶疲劳的智能车载香氛系统(申请号:201811118458.1),提出一种用于缓解驾驶疲劳的智能车载香氛系统,所述系统包括:疲劳特征数据库,用于存储预设的疲劳特征数据;疲劳监测模块,用于采集初始疲劳数据;数据处理模块,用于识别所述初始疲劳数据,并从所述初始疲劳数据中提取实际特征信息;特征比对模块,用于根据所述实际特征信息,调取疲劳特征数据库中的所述疲劳特征数据,并进行特征比对;控制信息生成模块,根据特征比对结果,生成控制信息;系统控制模块,用于根据所述控制信息开启或调节香氛装置;香氛装置,用于产生并释放有香味的气体。该发明通过监测驾驶员的驾驶状态,智能控制香氛系统,提高了行车安全,改善了用户体验。Chinese patent: An intelligent car fragrance system for relieving driving fatigue (application number: 201811118458.1), which proposes an intelligent car fragrance system for relieving driving fatigue, the system includes: a fatigue feature database for storing preset fatigue characteristic data; a fatigue monitoring module for collecting initial fatigue data; a data processing module for identifying the initial fatigue data and extracting actual feature information from the initial fatigue data; a feature comparison module for using According to the actual feature information, the fatigue feature data in the fatigue feature database is retrieved, and feature comparison is performed; the control information generation module generates control information according to the feature comparison result; the system control module is used for The control information is used to turn on or adjust the fragrance device; the fragrance device is used to generate and release scented gas. The invention improves the driving safety and improves the user experience by monitoring the driving state of the driver and intelligently controlling the fragrance system.

使用过程中,该系统通过采集驾驶员的面部表情数据和动作数据、心率数据、血压数据,并监测车速、方向盘、油门、刹车的操作特征信息,与疲劳特征数据库中相应类别的预设的疲劳特征数据进行比对。监测到不同的疲劳类型后,该系统通过释放不同类型的香味气体,缓解驾驶员的疲劳。During use, the system collects the driver's facial expression data and action data, heart rate data, blood pressure data, and monitors the operating characteristic information of vehicle speed, steering wheel, accelerator, and brake, and the corresponding category of preset fatigue in the fatigue characteristic database. feature data for comparison. After monitoring different types of fatigue, the system relieves the driver's fatigue by releasing different types of aroma gases.

中国专利:一种具有长途驾驶提神解困功效的雾化剂,公开了一种具有长途驾驶提神解困功效的雾化剂,属于汽车用品。该雾化剂含有的活性成分由石菖蒲挥发油、肉桂挥发油、冰片、薄荷油组成。在此成分的基础上还加入占活性成分总重量的70-90%的溶剂。该发明具有提神解困功效,无毒副作用,可有效解除长途驾驶的神经疲劳,提高注意力,同时该发明雾化速度非常均匀,活性成分能够充分、稳定地释放。Chinese patent: an atomizer with the effect of refreshing the mind during long-distance driving, discloses an atomizer with the effect of refreshing the mind during long-distance driving, and belongs to automotive supplies. The active ingredients contained in the atomizer are composed of calamus volatile oil, cinnamon volatile oil, borneol and peppermint oil. In addition to this ingredient, 70-90% of the solvent by weight of the total active ingredient is also added. The invention has the effect of refreshing sleepiness, has no toxic and side effects, can effectively relieve the nerve fatigue of long-distance driving, and improves the concentration. At the same time, the atomization speed of the invention is very uniform, and the active ingredients can be fully and stably released.

通过嗅觉刺激对驾驶行为的干预,一般基于嗅觉刺激对唤醒度、情绪等指标的影响,以对驾驶绩效产生影响。Intervention of driving behavior through olfactory stimuli is generally based on the influence of olfactory stimuli on indicators such as arousal and emotion, so as to influence driving performance.

唤醒度方面,研究发现,薄荷、桉树、迷迭香、柠檬的气味均对提升驾驶员的唤醒水平有一定影响作用,其中薄荷的干预效果最佳,持续性最强。实验结果表明,薄荷气味能够有效地减少驾驶员在驾驶过程中的眨眼频率,并提升驾驶员的横向控制能力(Yoshida etal.,2011)。In terms of arousal, the study found that the smells of mint, eucalyptus, rosemary, and lemon all had a certain effect on improving the driver's arousal level. Among them, peppermint had the best intervention effect and the strongest persistence. The experimental results show that the mint smell can effectively reduce the driver's blink frequency during driving and improve the driver's lateral control ability (Yoshida et al., 2011).

情绪方面,有研究表明,薰衣草、香草等气味均能提升驾驶员的平静、放松、舒适感,使驾驶员在驾驶过程中采用更低的车速,从而提升驾驶安全性(Mustafa,Rustam,Siran,2015)。In terms of emotions, studies have shown that lavender, vanilla and other smells can improve the driver's calm, relaxation, and comfort, so that the driver can use a lower speed during driving, thereby improving driving safety (Mustafa, Rustam, Siran, 2015).

上述几项现有技术都通过一定的嗅觉刺激对驾驶员的驾驶绩效进行了干预,但仍然存在一定的局限性。The above-mentioned existing technologies all intervene in the driver's driving performance through certain olfactory stimuli, but there are still certain limitations.

主要的局限性在于,几项技术对于驾驶行为的改善均集中在车速、横向控制能力等较为基础的驾驶行为指标。但驾驶是一项复杂的行为,车速、横向控制能力不能最有效地反映驾驶安全性。The main limitation is that the improvement of driving behavior by several technologies is concentrated on relatively basic driving behavior indicators such as vehicle speed and lateral control ability. But driving is a complex behavior, and vehicle speed and lateral control are not the most effective reflections of driving safety.

另外,这些香味为阈上刺激的方式对驾驶员的驾驶行为进行调节和干预,而气味的刺激可能会给驾驶员带来一些其他困扰,如驾驶员不舒适、不喜爱的气味反而产生干扰驾驶的反作用。In addition, these scents modulate and intervene in the driver's driving behavior in the form of suprathreshold stimulation, and the odor stimulation may bring some other troubles to the driver, such as the driver's uncomfortable and unfavorable odors that interfere with driving. reaction.

发明内容SUMMARY OF THE INVENTION

为克服现有技术的上述缺陷,本发明提出雌甾四烯的新用途,通过阈下方式提升驾驶员在驾驶行为当中的安全裕度,提高驾驶员的驾驶安全性和/或车距控制能力。In order to overcome the above-mentioned defects of the prior art, the present invention proposes a new application of estratetraene, which improves the safety margin of the driver in the driving behavior through the sub-threshold mode, and improves the driving safety and/or the distance control ability of the driver. .

本发明所提供的新用途为:雌甾四烯在提高驾驶员的驾驶安全性中的应用。The new application provided by the invention is: the application of estratetraene in improving the driving safety of drivers.

优选的,驾驶安全性为车距控制能力。Preferably, the driving safety is vehicle distance control capability.

进一步的,雌甾四烯配置为溶液。Further, the estratetraene is configured as a solution.

进一步的,雌甾四烯溶液以醇类为溶剂,优选的,溶剂为丙二醇。Further, the estratetraene solution uses alcohol as a solvent, preferably, the solvent is propylene glycol.

进一步的,雌甾四烯溶液的浓度高于100μM,优选的,浓度为500μM。Further, the concentration of the estratetraene solution is higher than 100 μM, preferably, the concentration is 500 μM.

进一步的,所述雌甾四烯对人体的作用为阈下刺激。Further, the effect of the estratetraene on the human body is subthreshold stimulation.

本发明提供的无味道的阈下刺激具有较好的灵活性,不需要驾驶员“闻”到任何气味,即可调节驾驶员的驾驶行为,提高驾驶安全性。The tasteless subthreshold stimulus provided by the invention has good flexibility, and the driver's driving behavior can be adjusted without the driver "smelling" any odor, and the driving safety can be improved.

附图说明Description of drawings

图1为雌甾四烯的分子结构图。Figure 1 is a diagram of the molecular structure of estratetraene.

为了能明确实现本发明的实施例的结构,在图中标注了特定的尺寸、结构和器件,但这仅为示意需要,并非意图将本发明限定在该特定尺寸、结构、器件和环境中,根据具体需要,本领域的普通技术人员可以将这些器件和环境进行调整或者修改,所进行的调整或者修改仍然包括在后附的权利要求的范围中。In order to clearly realize the structure of the embodiments of the present invention, specific dimensions, structures, and devices are marked in the drawings, but these are only for illustrative purposes, and are not intended to limit the present invention to the specific dimensions, structures, devices, and environments. Those of ordinary skill in the art can adjust or modify these devices and environments according to specific needs, and the adjustments or modifications are still included in the scope of the appended claims.

具体实施方式Detailed ways

下面结合附图和具体实施例对本发明提供的一种利用工控系统时序数据的预警方法及系统进行详细描述。A method and system for early warning using time series data of an industrial control system provided by the present invention will be described in detail below with reference to the accompanying drawings and specific embodiments.

在以下的描述中,将描述本发明的多个不同的方面,然而,对于本领域内的普通技术人员而言,可以仅仅利用本发明的一些或者全部结构或者流程来实施本发明。为了解释的明确性而言,阐述了特定的数目、配置和顺序,但是很明显,在没有这些特定细节的情况下也可以实施本发明。在其他情况下,为了不混淆本发明,对于一些众所周知的特征将不再进行详细阐述。In the following description, various aspects of the present invention will be described, however, to those of ordinary skill in the art, the present invention may be practiced using only some or all of the structures or processes of the present invention. For clarity of explanation, specific numbers, configurations, and orders are set forth, but it will be apparent that the invention may be practiced without these specific details. In other instances, well-known features have not been described in detail in order not to obscure the present invention.

本发明提出了雌甾四烯的一种新用途,用于提高驾驶员的驾驶安全性。驾驶安全性包括车距控制能力。The invention proposes a new application of estratetraene for improving the driving safety of drivers. Driving safety includes distance control capabilities.

雌甾四烯是类固醇物质,分子式为C18H22O,分子结构如图1所示,其来源与效应具有明显的信息素特征和性别特异性,因此被认为是一种可能的人类信息素。雌甾四烯由成年女性分泌,能够调节被试的情绪,但对于情绪调节作用的结果并不一致。Estrogen is a steroid substance with a molecular formula of C 18 H 22 O. Its molecular structure is shown in Figure 1. Its source and effect have obvious pheromone characteristics and gender specificity, so it is considered a possible human pheromone. . Estrogen is secreted by adult females and can regulate the emotions of the subjects, but the results on the effect of emotion regulation are inconsistent.

雌甾四烯可以制成溶液。雌甾四烯可以溶解在水、醇类等溶剂中。雌甾四烯溶液可以放置在如申请号201811118458.1所公开的香氛装置中,在驾驶过程中,打开香氛装置,溶液挥发,即可被吸入驾驶员鼻中。Estatetraene can be made into solution. Estatetraene can be dissolved in water, alcohol and other solvents. The estratetraene solution can be placed in the fragrance device as disclosed in Application No. 201811118458.1. During driving, the fragrance device is opened and the solution is volatilized, and can be inhaled into the driver's nose.

雌甾四烯对驾驶员的影响,是通过一种阈下的方式,即不通过实际的气味影响驾驶员的行为,而是通过犁鼻器接收,中转向杏仁核、下丘脑等脑区投射,以驾驶员无法感知到的方式影响驾驶员的行为。这样的行为调节方式可以减少阈上嗅觉刺激(如薄荷、薰衣草等味道)带来的其他影响,如驾驶员不喜爱、不习惯该气味。The effect of estratetraene on the driver is in a subliminal way, that is, it does not affect the driver's behavior through the actual smell, but is received through the vomeronasal organ, and the mid-turn to the amygdala, hypothalamus and other brain areas project. , which affects the driver's behavior in a way that the driver cannot perceive. Such behavioral regulation can reduce other effects of suprathreshold olfactory stimuli (such as mint, lavender, etc.), such as the driver's dislike and unaccustomed to the smell.

雌甾四烯也可以制成雾化剂等,被吸入驾驶员鼻中。其作用机理与上面所述相同。Estrogen can also be made into aerosols, etc., which are inhaled into the driver's nose. Its mechanism of action is the same as described above.

实施例1:Example 1:

雌甾四烯溶液以丙二醇为溶剂,配置浓度为500μM。为验证该类嗅觉刺激干预是否有效,采用驾驶模拟系统进行验证。The estratetraene solution uses propylene glycol as the solvent, and the concentration is 500 μM. In order to verify whether this type of olfactory stimulation intervention is effective, a driving simulation system is used for verification.

将一批驾驶员分为实验组(使用雌甾四烯溶液)和对照组(使用空白溶液,除了不添加雌甾四烯,其余与实验组溶液成分相同)。A batch of drivers was divided into an experimental group (using estratetraene solution) and a control group (using a blank solution, except that no estratetraene was added, the rest of the solution was the same as the experimental group).

两组驾驶员均在驾驶模拟器上完成跟车任务:道路场景为单侧宽度4.8米的双向车道,中间有双黄线。全长9.9km,由19个弯道组成,其中10个左转弯,9个右转弯,所有弯道曲度均相同。驾驶员需跟随前方车辆并以20m/s的速度定速巡航。此时,与前方车辆距离36.58m,且前方车辆与驾驶员所驾驶车辆保持相同速度。跟车行驶一段时间后,前车刹车,同时尾灯亮起,并在3.28s的时间内减速至13.41m/s。驾驶员在看到前车尾灯亮起时,需按照日常驾驶习惯踩刹车。由于前后辆车起始刹车时间不同步,且后车较晚,因此两车之间的距离会缩小。当两车距离缩小为30.48m时,前车速度在10s之内增加为268m/s并驶离。整个道路驾驶过程中,跟车事件一共发生14次,刹车事件触发前的跟车行驶时间随机。在模拟时,持续释放各组实验所用的溶液。Both groups of drivers completed the following task on the driving simulator: the road scene was a two-way lane with a width of 4.8 meters on one side and a double yellow line in the middle. The total length is 9.9km and consists of 19 curves, including 10 left turns and 9 right turns, all of which have the same curvature. The driver needs to follow the vehicle ahead and cruise at a speed of 20m/s. At this time, the distance from the vehicle in front is 36.58m, and the vehicle in front maintains the same speed as the vehicle driven by the driver. After following the car for a period of time, the car in front braked and the taillights turned on at the same time, and decelerated to 13.41m/s within 3.28s. When the driver sees the front taillights on, he needs to apply the brakes according to his daily driving habits. Since the initial braking time of the front and rear cars is not synchronized, and the rear car is late, the distance between the two cars will be reduced. When the distance between the two vehicles is reduced to 30.48m, the speed of the vehicle in front increases to 268m/s within 10s and drives away. During the entire road driving process, the following events occurred 14 times in total, and the following driving time before the braking event was triggered was random. During the simulation, the solutions used in each group of experiments were continuously released.

记录驾驶员在每次跟车事件当中的最小TTC,结果表明,实验组的最小TTC显著高于对照组,表明雌甾四烯溶液提升了驾驶员在驾驶行为当中的车距控制能力,提高了驾驶安全性。相关数据见表1。The minimum TTC of the driver in each following event was recorded. The results showed that the minimum TTC of the experimental group was significantly higher than that of the control group. driving safety. The relevant data are shown in Table 1.

表1雌甾四烯和对照组最小TTC对比Table 1 Comparison of minimum TTC between estratetraene and control group

Figure BDA0002487615170000051
Figure BDA0002487615170000051

注:样本量=40,*p<0.05Note: sample size = 40, *p<0.05

t、p为统计学t检验中的检验值,是否具有显著性是统计学中的基本方法,此处不再具体计算。t and p are the test values in the statistical t-test. Whether it is significant or not is the basic method in statistics, and will not be calculated in detail here.

实施例2Example 2

取浓度为100μM的雌甾四烯溶液重复了上述实验,结果表明,实验组的最小TTC同样显著高于对照组,表明雌甾四烯溶液提升了驾驶员在驾驶行为当中的车距控制能力,提高了驾驶安全性。The above experiment was repeated with 100 μM estratetraene solution. The results showed that the minimum TTC of the experimental group was also significantly higher than that of the control group, indicating that the estratetraene solution improved the driver’s ability to control the distance between vehicles. Improved driving safety.

实施例3Example 3

取浓度为700μM的雌甾四烯溶液重复了上述实验,结果表明,实验组的最小TTC同样显著高于对照组,表明雌甾四烯溶液提升了驾驶员在驾驶行为当中的车距控制能力,提高了驾驶安全性。The above experiments were repeated with the estratetraene solution with a concentration of 700 μM. The results showed that the minimum TTC of the experimental group was also significantly higher than that of the control group, indicating that the estratetraene solution improved the driver’s ability to control the distance between vehicles. Improved driving safety.

根据常识可以得出,浓度升高,释放的雌甾四烯会增加,而浓度为500uM和700uM的雌甾四烯溶液能提高驾驶员的驾驶安全性,那么高于该浓度的雌甾四烯溶液也同样能提高驾驶员的驾驶安全性。According to common sense, as the concentration increases, the released estratetraene will increase, and the estratetraene solution with the concentration of 500uM and 700uM can improve the driving safety of the driver, then the estratetraene higher than the concentration can improve the driving safety of the driver. The solution also improves the driver's driving safety.

实际中,TTC指标比车速、横向控制等基础驾驶指标更能反应驾驶员的驾驶安全性或车距控制能力。In practice, the TTC index can better reflect the driver's driving safety or distance control ability than basic driving indicators such as vehicle speed and lateral control.

实验采用车载香氛释放装置,只对物质进行扩散。事实上,对驾驶行为产生干预是雌甾四烯本身的作用,采用其他释放方式,如敞口瓶、管道释放等均可以达到类似效果,但其实现的基本原理与本技术相同。The experiment uses a vehicle-mounted fragrance release device, which only diffuses the substance. In fact, the intervention on driving behavior is the function of estratetraene itself, and other release methods, such as open bottle, pipeline release, etc., can achieve similar effects, but the basic principle of its realization is the same as this technology.

实验采用STISIM DRIVE M100模拟器,莱仕达雷驰方向盘和踏板进行了模拟驾驶的开发,并设计了跟车任务进行验证。其他驾驶模拟设备,包括但不限于简易汽车驾驶模拟器、单屏幕主动式汽车驾驶模拟器、液压伺服体感模拟器、以及一般计算机使用鼠标键盘进行操作等也可以作为实现此任务的载体,其他模拟驾驶任务也可以通过此种嗅觉刺激方式检验干预效果,但其实现的基本原理与本技术相同。The experiment uses STISIM DRIVE M100 simulator, Lai Shida Leichi steering wheel and pedals to develop simulated driving, and design a car following task for verification. Other driving simulation devices, including but not limited to simple car driving simulators, single-screen active car driving simulators, hydraulic servo somatosensory simulators, and general computer operations using a mouse and keyboard, can also be used as carriers for this task. Driving tasks can also test the effect of intervention through this olfactory stimulation, but the basic principle of its realization is the same as this technology.

最后应说明的是,以上实施例仅用以描述本发明的技术方案而不是对本技术方法进行限制,本发明在应用上可以延伸为其他的修改、变化、应用和实施例,并且因此认为所有这样的修改、变化、应用、实施例都在本发明的精神和教导范围内。Finally, it should be noted that the above embodiments are only used to describe the technical solutions of the present invention rather than to limit the technical methods of the present invention, and the present invention can be extended to other modifications, changes, applications and embodiments in application, and therefore it is considered that all such Modifications, variations, applications, and embodiments are within the spirit and teachings of the present invention.

Claims (8)

1. Use of estratetraene for improving the driving safety of a driver.
2. Use according to claim 1, characterized in that the driving safety is a vehicle distance control capability.
3. The use according to any one of claims 1 to 2, wherein the estratetraene is formulated as a solution or aerosol.
4. Use according to claim 3, characterized in that the solvent of the solution is an alcohol.
5. Use according to claim 3, characterized in that the solvent of the solution is propylene glycol.
6. The use according to any one of claims 3 to 4 wherein the concentration of the estratetraene solution is greater than 100 μ M.
7. The use according to any one of claims 3 to 4 wherein the concentration of the estratetraene solution is 500 μ M.
8. The use according to any one of claims 1 to 7 wherein the effect of estratetraene on the human body is subthreshold stimulation.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114159448A (en) * 2021-12-10 2022-03-11 深圳先进技术研究院 Application of steroid substance in preparation of preparation for improving attention

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1101648A (en) * 1993-06-15 1995-04-19 弗林公司 Estrene steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical
CN1167489A (en) * 1994-09-29 1997-12-10 弗伦有限公司 A new estrone with hypothalamic inducing effect
US20060252738A1 (en) * 2005-05-06 2006-11-09 Phero Tech Inc. Method for preparing and using water-based steroid pheromone compositions
CN1903704A (en) * 2005-07-25 2007-01-31 林卓敏 Health type car or automobile capable of automatically proceeding oxygen producing and enriching
CN106394559A (en) * 2016-11-17 2017-02-15 吉林大学 Multi-target driving behavior evaluation analytical method based on environmental perception information
CN109334406A (en) * 2018-09-25 2019-02-15 吉利汽车研究院(宁波)有限公司 An intelligent car fragrance system for relieving driving fatigue
CN109646380A (en) * 2019-02-27 2019-04-19 汪键 A kind of solid perfume and preparation method thereof with bacteria resistance function of refreshing oneself
CN109927510A (en) * 2017-12-17 2019-06-25 广州煜子志电子科技有限公司 A kind of device for resisting fatigue driving

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1101648A (en) * 1993-06-15 1995-04-19 弗林公司 Estrene steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical
CN1167489A (en) * 1994-09-29 1997-12-10 弗伦有限公司 A new estrone with hypothalamic inducing effect
US20060252738A1 (en) * 2005-05-06 2006-11-09 Phero Tech Inc. Method for preparing and using water-based steroid pheromone compositions
CN1903704A (en) * 2005-07-25 2007-01-31 林卓敏 Health type car or automobile capable of automatically proceeding oxygen producing and enriching
CN106394559A (en) * 2016-11-17 2017-02-15 吉林大学 Multi-target driving behavior evaluation analytical method based on environmental perception information
CN109927510A (en) * 2017-12-17 2019-06-25 广州煜子志电子科技有限公司 A kind of device for resisting fatigue driving
CN109334406A (en) * 2018-09-25 2019-02-15 吉利汽车研究院(宁波)有限公司 An intelligent car fragrance system for relieving driving fatigue
CN109646380A (en) * 2019-02-27 2019-04-19 汪键 A kind of solid perfume and preparation method thereof with bacteria resistance function of refreshing oneself

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
前田京子: "《薄荷油的乐趣》", 30 April 2019, 华夏出版社 *
叶玉婷: "信息素影响人类行为吗?", 《科学通报》 *
尼尔·R.卡尔森: "《行为生理学 第8版》", 31 December 2014, 上海人民出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114159448A (en) * 2021-12-10 2022-03-11 深圳先进技术研究院 Application of steroid substance in preparation of preparation for improving attention
WO2023104166A1 (en) * 2021-12-10 2023-06-15 深圳先进技术研究院 Application of steroid substance in preparation of preparation for improving attention

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