CN111407462A - Novel courage pancreatic duct support of fibroin material preparation - Google Patents
Novel courage pancreatic duct support of fibroin material preparation Download PDFInfo
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- CN111407462A CN111407462A CN202010145768.3A CN202010145768A CN111407462A CN 111407462 A CN111407462 A CN 111407462A CN 202010145768 A CN202010145768 A CN 202010145768A CN 111407462 A CN111407462 A CN 111407462A
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- pancreatic duct
- pipe body
- limiting
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- fibroin material
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Images
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/043—Proteins; Polypeptides; Degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2002/041—Bile ducts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
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- Surgery (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention discloses a bile pancreatic duct bracket made of a novel fibroin material, which comprises a duct body, wherein one end of the duct body is provided with a limiting sleeve, the end part of the limiting sleeve is fixedly provided with an integrated mounting tube, the inner side of the end part of the mounting tube is provided with an inner ring groove, the surface of one end of the duct body is provided with a placing groove matched with the inner ring groove, the inner wall of the inner ring groove is equidistantly fixed with a plurality of limiting lugs A with annular structures, the surface of the placing groove is fixed with a limiting lug B which is symmetrical to the limiting lug A, and the limiting lug A and the limiting lug B are in a fitting structure; through the stop collar and the installation section of thick bamboo of design, can in use, reduce the use quantity of antislip strip, improve the travelling comfort of using, in use adjusts the stop collar of not unidimensional according to the bile duct of disease and pancreatic duct actual diameter simultaneously, and it is more nimble to use.
Description
Technical Field
The invention belongs to the technical field of biliopancreatic duct brackets, and particularly relates to a biliopancreatic duct bracket made of a novel fibroin material.
Background
Biomedical materials are special materials for diagnosing, treating, repairing or replacing damaged tissues and organs of organisms and helping tissue growth, animal silk proteins are used as the biomedical materials for hundreds of years and are used as wound sutures at first, silk has various characteristics as the biomedical materials, so that the silk has wide application in the aspects of bone tissues, ligaments, tendons, skin, blood vessels, trachea, muscles, nerves and the like, and scientists particularly perform deep research and clinical application in the aspects of bone tissues and blood vessel tissues. At present, biomedical materials are also used for manufacturing bile-pancreatic duct stents.
Present bile pancreatic duct support (including metal, metal covering membrane and plastic support) all need the antislip strip spacing to the support position when using, nevertheless because the slope form of antislip strip formula as an organic whole, placing, still can have certain uncomfortable, consequently there is great improvement space, the antislip strip can't be adjusted according to different patient's bile duct diameter simultaneously, the flexibility of use is relatively poor to a series of problems can appear in clinical diagnosis and treatment and application: 1. for patients with benign biliary and pancreatic diseases such as: after the bile duct and pancreatic duct are supported by the stent, the patient can be subjected to the phenomena of biliary tract bleeding and biliary pancreatic duct restenosis after the patient is taken out for the second time; 2. even if the current metal covered stent on the market is applied to the biliary duct and pancreatic duct stenosis caused by the malignant tumor of the biliary duct and the pancreas, the risk that the stent needs to be repeatedly implanted from the first stent for a plurality of times due to the growth of the tumor is possible, and the pain, the risk and the self-cost medical expense of a patient are increased.
Therefore, in view of better biodegradability, good biocompatibility and biosafety, excellent mechanical property, processability, digestibility and anticoagulation of the fibroin, the biological bile-pancreatic duct stent has the characteristics of rich source, low price, convenience, easy obtainment, low immunogenicity and the like, so that the biological bile-pancreatic duct stent is invented to bring new gospel to clinical vast biliary tract and pancreatic disease patients.
Disclosure of Invention
The invention aims to provide a novel bile-pancreatic duct stent made of fibroin materials, which aims to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: the utility model provides a novel courage pancreatic duct support of fibroin material preparation, includes the body, the one end of body is provided with the stop collar, the end fixing of stop collar has the installation section of thick bamboo of integral type, the inner ring groove has been seted up to the tip inboard of installation section of thick bamboo, the standing groove with inner ring groove looks adaptation is seted up on the one end surface of body, the inner wall equidistance of inner ring groove is fixed with the spacing lug A of a plurality of loop configuration, the fixed surface of standing groove has the spacing lug B that is the symmetry form with spacing lug A, spacing lug A is laminated structure with spacing lug B.
Preferably, the cross sections of the limiting convex block a and the limiting convex block B are in a right-angled triangle structure, and the two are flexible material members.
Preferably, the stop collar is of a hollow circular truncated cone structure, the mounting cylinder is of a hollow cylindrical structure, and the aperture of the stop collar is equal to that of the mounting cylinder.
Preferably, an inner arc-shaped groove is formed in the middle of the inner portion of the pipe body, and the cross section of the inner arc-shaped groove is of an arc-shaped structure.
Preferably, a plurality of through holes are formed in the surface of the pipe body, and the through holes are distributed spirally.
Preferably, the pipe body is a flexible component, the surface of the other end of the pipe body is provided with an anti-slip strip, and the anti-slip strip is made of the same material as the pipe body.
Preferably, the inner diameter of the mounting cylinder is equal to the inner diameter of the pipe body, and the diameter of the bottom end of the limiting sleeve is one point three times of the diameter of the pipe body.
Preferably, the aperture of the through hole is one sixth of the aperture of the tube body, and the through hole is arranged on the surface of the tube body in a penetrating manner.
Compared with the prior art, the invention has the beneficial effects that:
1. the designed limiting sleeve and the mounting cylinder can reduce the using number of the anti-slip strips and improve the using comfort in use, and meanwhile, the limiting sleeves with different sizes are adjusted according to the actual width of the bile duct of a patient in use, so that the limiting sleeve and the mounting cylinder are more flexible to use;
2. the artificial blood vessel made of silk fiber can prevent the permeation of blood, thereby avoiding early thrombosis, the silk fibroin has obvious advantages as a drug slow-release material, has good biocompatibility, does not influence the activity of the drug, the biological safety, degradability, immunogenicity and excellent mechanical structure of the silk fibroin material, and the silk in China has rich production area and low price;
3. by the designed inner arc-shaped groove, the width of the middle part of the pipe body can be increased and the risk of blockage can be reduced in use; the spiral through hole is designed, so that the air permeability of the pipe body can be effectively guaranteed.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is an enlarged view of area A of FIG. 1 according to the present invention;
FIG. 3 is a front view of the stop collar of the present invention;
FIG. 4 is a cross-sectional view of a tubular body of the present invention;
FIG. 5 is an expanded view of the tube of the present invention;
in the figure: 1. a pipe body; 2. a through hole; 3. a limiting sleeve; 4. an inner ring groove; 5. mounting the cylinder; 6. a limiting bump A; 7. a limiting bump B; 8. an inner arc-shaped groove.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
Referring to fig. 1 to 3, the present invention provides a technical solution: the utility model provides a novel bile pancreatic duct support of fibroin material preparation, including body 1, the one end of body 1 is provided with stop collar 3, the end fixing of stop collar 3 has the installation section of thick bamboo 5 of integral type, stop collar 3 and installation section of thick bamboo 5 through the design, can in use, reduce the use quantity of antislip strip, improve the travelling comfort of using, in use simultaneously adjusts not unidimensional stop collar according to the bile duct actual width of disease, it is more nimble to use, inner ring groove 4 has been seted up to the tip inboard of installation section of thick bamboo 5, the standing groove with inner ring groove 4 looks adaptation is seted up on the one end surface of body 1, the inner wall equidistance of inner ring groove 4 is fixed with the spacing lug A6 of a plurality of loop configuration, the fixed surface of standing groove has the spacing lug B7 that is the symmetry form with spacing lug A6, spacing lug A6 is laminated structure with spacing lug B.
In this embodiment, preferably, the cross sections of the limiting protrusion a6 and the limiting protrusion B7 are right-angled triangle structures, and both are flexible members.
In this embodiment, preferably, the limiting sleeve 3 is a hollow circular truncated cone structure, the mounting tube 5 is a hollow cylindrical structure, and the aperture of the limiting sleeve 3 is equal to that of the mounting tube 5.
In this embodiment, preferably, the pipe body 1 is a flexible member, and an anti-slip strip is installed on the surface of the other end of the pipe body 1, and the anti-slip strip is made of the same material as the pipe body 1.
In this embodiment, preferably, the inner diameter of the mounting tube 5 is equal to the inner diameter of the tube body 1, and the bottom end diameter of the position-limiting sleeve 3 is one point three times of the diameter of the tube body 1.
In this embodiment, preferably, the diameter of the through hole 2 is one sixth of the diameter of the tube 1, and the through hole 2 is formed on the surface of the tube 1 in a penetrating manner.
Example 2
Referring to fig. 1 to 5, the present invention provides a technical solution: the utility model provides a novel bile pancreatic duct support of fibroin material preparation, including body 1, the one end of body 1 is provided with stop collar 3, the end fixing of stop collar 3 has the installation section of thick bamboo 5 of integral type, stop collar 3 and installation section of thick bamboo 5 through the design, can in use, reduce the use quantity of antislip strip, improve the travelling comfort of using, in use simultaneously adjusts not unidimensional stop collar according to the bile duct actual width of disease, it is more nimble to use, inner ring groove 4 has been seted up to the tip inboard of installation section of thick bamboo 5, the standing groove with inner ring groove 4 looks adaptation is seted up on the one end surface of body 1, the inner wall equidistance of inner ring groove 4 is fixed with the spacing lug A6 of a plurality of loop configuration, the fixed surface of standing groove has the spacing lug B7 that is the symmetry form with spacing lug A6, spacing lug A6 is laminated structure with spacing lug B.
In this embodiment, preferably, the cross sections of the limiting protrusion a6 and the limiting protrusion B7 are right-angled triangle structures, and both are flexible members.
In this embodiment, preferably, the limiting sleeve 3 is a hollow circular truncated cone structure, the mounting tube 5 is a hollow cylindrical structure, and the aperture of the limiting sleeve 3 is equal to that of the mounting tube 5.
In this embodiment, preferably, the inner arc-shaped groove 8 is formed in the middle of the inner portion of the pipe body 1, and the inner arc-shaped groove 8 is designed to increase the width of the middle of the pipe body 1 and reduce the risk of blockage.
In this embodiment, preferred, a plurality of through-holes 2 have been seted up on the surface of body 1, and a plurality of through-holes 2 are the heliciform and distribute, and the design is spiral helicine through-hole 2, can effectively guarantee body 1's air permeability, and the cross section of interior arc wall 8 is the arc structure.
In this embodiment, preferably, the pipe body 1 is a flexible member, and an anti-slip strip is installed on the surface of the other end of the pipe body 1, and the anti-slip strip is made of the same material as the pipe body 1.
In this embodiment, preferably, the inner diameter of the mounting tube 5 is equal to the inner diameter of the tube body 1, and the bottom end diameter of the position-limiting sleeve 3 is one point three times of the diameter of the tube body 1.
In this embodiment, preferably, the diameter of the through hole 2 is one sixth of the diameter of the tube 1, and the through hole 2 is formed on the surface of the tube 1 in a penetrating manner.
The working principle and the using process of the invention are as follows: when the silk scaffold is used, the silk material is prepared, and the silk has the characteristics of good mechanical property, good air permeability, oxygen permeability, biocompatibility, controllable biodegradability and the like, so that the silk material has great application value in the directions of tissue engineering, a drug loading system, dressing and the like, the mechanical property of the silk is similar to that of biological tendons, the mechanical form of a pre-formed new tissue can be maintained in the application of the tissue engineering, the silk has the characteristics that other natural or artificial materials do not have, the silk has no sensitization, irritation and genetic toxicity, obvious inflammatory reaction can not be caused when the silk is implanted into a body, the cytotoxicity of a tubular scaffold prepared from silk fibroin is low, the silk scaffold can be used for culturing fibroblasts to promote the growth and proliferation of cells, and the silk and polylactic acid composite scaffold can promote the proliferation of endothelial cells The silk has various characteristics as biomedical materials, so that the silk has wide application in the aspects of bone tissues, ligaments, tendons, skin, blood vessels, trachea, muscles, nerves and the like, the silk has an anticoagulant function due to a special amino acid arrangement structure in silk fibroin, has better biocompatibility compared with synthetic materials, is more favorable for endothelialization of an artificial blood vessel, in the subsequent practical use, the matched limiting sleeve 3 is selected according to the width of a bile duct of a patient, then the silk is connected with the tube body 1 through the mounting tube 5 at one end of the limiting sleeve 3, in the connection, the limiting lug A6 on the inner wall of the inner ring groove 4 is extruded and deformed by the limiting lug B7, the mounting tube 5 is continuously inserted at the moment, so that all the limiting lugs A6 are mutually attached to the right-angle sides of the limiting lugs B7, and in the use, through the arc column structure that interior arc wall 8 formed, increase the inside space of body 1 to the surface takes place to block up the condition in body 1 inner zone, and guarantees the gas permeability of body 1 through being spiral helicine through-hole 2.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. The utility model provides a bile pancreatic duct support of novel fibroin material preparation, includes body (1), its characterized in that: the one end of body (1) is provided with stop collar (3), the end fixing of stop collar (3) has an installation section of thick bamboo (5) of integral type, interior annular groove (4) have been seted up to the tip inboard of installation section of thick bamboo (5), the standing groove with interior annular groove (4) looks adaptation is seted up on the one end surface of body (1), the inner wall equidistance of interior annular groove (4) is fixed with spacing lug A (6) of a plurality of loop configuration, the surface fixing of standing groove has spacing lug B (7) that are the symmetry form with spacing lug A (6), spacing lug A (6) are laminated structure with spacing lug B (7).
2. The novel bile pancreatic duct stent made of fibroin material as claimed in claim 1, is characterized in that: the cross sections of the limiting lug A (6) and the limiting lug B (7) are in right-angled triangle structures, and the limiting lug A and the limiting lug B are flexible material components.
3. The novel bile pancreatic duct stent made of fibroin material as claimed in claim 1, is characterized in that: the limiting sleeve (3) is of a hollow round platform structure, the mounting cylinder (5) is of a hollow cylindrical structure, and the aperture of the limiting sleeve (3) is equal to that of the mounting cylinder (5).
4. The novel bile pancreatic duct stent made of fibroin material as claimed in claim 1, is characterized in that: an inner arc-shaped groove (8) is formed in the middle of the inner portion of the pipe body (1), and the cross section of the inner arc-shaped groove (8) is of an arc-shaped structure.
5. The novel bile pancreatic duct stent made of fibroin material as claimed in claim 4, characterized in that: a plurality of through-holes (2) are seted up on the surface of body (1), and are a plurality of through-holes (2) are the heliciform and distribute.
6. The novel bile pancreatic duct stent made of fibroin material as claimed in claim 1, is characterized in that: the pipe body (1) is a flexible material component, an anti-slip strip is arranged on the surface of the other end of the pipe body (1), and the anti-slip strip is made of the same material as the pipe body (1).
7. The novel bile pancreatic duct stent made of fibroin material as claimed in claim 3, characterized in that: the inner diameter of the installation barrel (5) is equal to that of the pipe body (1), and the diameter of the bottom end of the limiting sleeve (3) is one point three times that of the pipe body (1).
8. The novel bile pancreatic duct stent made of fibroin material as claimed in claim 5, characterized in that: the aperture of the through hole (2) is one sixth of the aperture of the pipe body (1), and the through hole (2) is arranged on the surface of the pipe body (1) in a penetrating manner.
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| CN202010145768.3A CN111407462A (en) | 2020-02-26 | 2020-02-26 | Novel courage pancreatic duct support of fibroin material preparation |
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| CN202010145768.3A CN111407462A (en) | 2020-02-26 | 2020-02-26 | Novel courage pancreatic duct support of fibroin material preparation |
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| CN117898868A (en) * | 2024-03-19 | 2024-04-19 | 北京阿迈特医疗器械有限公司 | Biliary pancreatic duct support capable of automatically discharging human body and preparation method |
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