CN111297342A - Heart rhythm measuring method based on egg embryo blood flow information - Google Patents
Heart rhythm measuring method based on egg embryo blood flow information Download PDFInfo
- Publication number
- CN111297342A CN111297342A CN201911145896.1A CN201911145896A CN111297342A CN 111297342 A CN111297342 A CN 111297342A CN 201911145896 A CN201911145896 A CN 201911145896A CN 111297342 A CN111297342 A CN 111297342A
- Authority
- CN
- China
- Prior art keywords
- information
- blood flow
- position line
- heart rhythm
- phase information
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000017531 blood circulation Effects 0.000 title claims abstract description 25
- 230000033764 rhythmic process Effects 0.000 title claims abstract description 24
- 210000001161 mammalian embryo Anatomy 0.000 title claims abstract description 22
- 238000000034 method Methods 0.000 title claims abstract description 14
- 238000000691 measurement method Methods 0.000 claims abstract description 6
- 230000009466 transformation Effects 0.000 claims abstract description 4
- 238000012545 processing Methods 0.000 claims description 10
- 238000012552 review Methods 0.000 claims description 6
- 230000003595 spectral effect Effects 0.000 claims description 4
- 238000000605 extraction Methods 0.000 claims description 3
- 238000005070 sampling Methods 0.000 claims description 3
- 210000000709 aorta Anatomy 0.000 abstract description 3
- 238000001228 spectrum Methods 0.000 abstract 1
- 238000012014 optical coherence tomography Methods 0.000 description 17
- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
- 238000005859 coupling reaction Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000003384 imaging method Methods 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 210000002257 embryonic structure Anatomy 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- 230000001133 acceleration Effects 0.000 description 1
- 210000000748 cardiovascular system Anatomy 0.000 description 1
- 230000008094 contradictory effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 210000004088 microvessel Anatomy 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 238000012634 optical imaging Methods 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 230000036417 physical growth Effects 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 230000008467 tissue growth Effects 0.000 description 1
- 238000003325 tomography Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/024—Measuring pulse rate or heart rate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0066—Optical coherence imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/026—Measuring blood flow
- A61B5/0261—Measuring blood flow using optical means, e.g. infrared light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7253—Details of waveform analysis characterised by using transforms
- A61B5/7257—Details of waveform analysis characterised by using transforms using Fourier transforms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/40—Animals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Surgery (AREA)
- Public Health (AREA)
- Pathology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Physiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Hematology (AREA)
- Mathematical Physics (AREA)
- Artificial Intelligence (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Psychiatry (AREA)
- Signal Processing (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Abstract
本发明公开了一种基于鸡蛋胚胎血流信息的心律测量方法,该方法基于OCT扫描系统,包括:步骤1、将扫描区域横向等分为多个位置线区间;步骤2、通过OCT扫描系统扫描位置线区间,得到在扫描区域中血流在不同的位置线区间上的速度信息;步骤3、对所述速度信息进行傅里叶谱变换得到频率‑加速度关系曲线,根据频率‑加速度关系曲线得到心律。通过OCT扫描系统对于扫描区域进行有深度的扫描,而且,可以利用鸡蛋胚胎大动脉的血流信息从侧面上得到鸡蛋胚胎的心律。相对于现有技术,该方法得到的心律信息更加完整和准确。本发明主要用于鸡蛋胚胎的研究工作中。
The invention discloses a heart rhythm measurement method based on egg embryo blood flow information. The method is based on an OCT scanning system, comprising: step 1, dividing the scanning area horizontally into multiple position line intervals; step 2, scanning through the OCT scanning system Position line interval, obtain the speed information of blood flow on different position line intervals in the scanning area; Step 3, perform Fourier spectrum transformation on the speed information to obtain the frequency-acceleration relationship curve, obtain according to the frequency-acceleration relationship curve heart rate. The scanning area is deeply scanned by the OCT scanning system, and the heart rhythm of the egg embryo can be obtained from the side by using the blood flow information of the aorta of the egg embryo. Compared with the prior art, the heart rhythm information obtained by this method is more complete and accurate. The invention is mainly used in the research work of egg embryo.
Description
技术领域technical field
本发明涉及光学成像技术领域,特别涉及一种基于鸡蛋胚胎血流信息的心律测量方法。The invention relates to the technical field of optical imaging, in particular to a heart rhythm measurement method based on egg embryo blood flow information.
背景技术Background technique
心脏的发育情况及周边血流的流动情况都会对动物的后续发育,包括组织及形体上的生长造成影响。光学相干层析成像技术(OCT)是20世纪90年代逐步发展而成的一种新的三维层析成像技术,通常使用宽带光源来实现低相干干涉,从而获得较高的分辨率,一般在10μm左右。目前OCT在心血管系统方面的应用有将光谱OCT成像技术与多普勒技术相结合来检测高度散射生物组织的血流速度,并同时进行组织结构成像,常用于亚表层微血管直径和血流速度分布的测量。The development of the heart and the flow of peripheral blood flow will affect the subsequent development of the animal, including tissue and physical growth. Optical coherence tomography (OCT) is a new three-dimensional tomography technology gradually developed in the 1990s. It usually uses a broadband light source to achieve low coherence interference, so as to obtain higher resolution, generally 10μm. about. At present, the application of OCT in the cardiovascular system includes the combination of spectral OCT imaging technology and Doppler technology to detect the blood flow velocity of highly scattered biological tissues, and to perform tissue structure imaging at the same time. It is often used for subsurface microvessel diameter and blood flow velocity distribution. Measurement.
现有的对鸡蛋胚胎进行心律测量的方法是通过直接采集待测鸡蛋胚胎心脏区域的图像,The existing method for measuring the heart rhythm of egg embryos is to directly acquire the image of the heart region of the egg embryo to be tested,
利用激光散斑原理以动态信号和静态信号之比作为成像参量得出心律曲线图,再计算一分钟内所述心律曲线图上周期的个数,得到待测鸡蛋胚胎的心律值。该方法需要作用在鸡蛋胚胎的心脏部位,十分不方便。Using the laser speckle principle, the ratio of the dynamic signal and the static signal is used as the imaging parameter to obtain the heart rhythm graph, and then the number of cycles on the heart rhythm graph in one minute is calculated to obtain the heart rhythm value of the egg embryo to be tested. This method needs to act on the heart of the egg embryo, which is very inconvenient.
发明内容SUMMARY OF THE INVENTION
本发明的目的是提供一种基于鸡蛋胚胎血流信息的心律测量方法,以解决现有技术中所存在的一个或多个技术问题,至少提供一种有益的选择或创造条件。The purpose of the present invention is to provide a heart rhythm measurement method based on egg embryo blood flow information, so as to solve one or more technical problems existing in the prior art, and at least provide a beneficial choice or create conditions.
本发明解决其技术问题的解决方案是:一种基于鸡蛋胚胎血流信息的心律测量方法,该方法基于OCT扫描系统,包括:The solution of the present invention to solve the technical problem is: a method for measuring heart rhythm based on blood flow information of egg embryos, the method is based on an OCT scanning system, and includes:
步骤1、将扫描区域横向等分为多个位置线区间;Step 1. Divide the scanning area horizontally into multiple position line intervals;
步骤2、通过OCT扫描系统扫描位置线区间,得到在扫描区域中血流在不同的位置线区间上的速度信息;Step 2. Scan the position line interval by the OCT scanning system, and obtain the velocity information of blood flow on different position line intervals in the scanning area;
步骤3、对所述速度信息进行傅里叶谱变换得到频率-加速度关系曲线,根据频率-加速度关系曲线得到心律。Step 3: Perform Fourier spectral transformation on the speed information to obtain a frequency-acceleration relationship curve, and obtain a heart rhythm according to the frequency-acceleration relationship curve.
进一步,步骤2的子步骤包括:Further, the sub-steps of step 2 include:
步骤2.1、通过OCT扫描系统对位置线区间进行两次截面扫描,得到第一截面图和第二截面图;Step 2.1, perform two cross-sectional scans on the position line interval through the OCT scanning system to obtain the first cross-sectional view and the second cross-sectional view;
步骤2.2、对第一截面图进行非节点边界三次样条插值处理后再进行傅里叶变换得到相位信息,所述相位信息记为第一相位信息;对第二截面图进行非节点边界三次样条插值处理后再进行傅里叶变换得到相位信息,所述相位信息记为第二相位信息;Step 2.2: Perform non-node boundary cubic spline interpolation processing on the first cross-sectional image, and then perform Fourier transform to obtain phase information, which is recorded as the first phase information; perform non-node boundary cubic spline sampling on the second cross-sectional image. After the strip interpolation processing, Fourier transform is performed to obtain phase information, and the phase information is denoted as second phase information;
步骤2.3、根据速度模型得到血流在所述位置线区间的速度信息;Step 2.3, obtaining the velocity information of the blood flow in the position line interval according to the velocity model;
步骤2.4、重复步骤2.1至步骤2.3直至得到所有位置线区间的速度信息;Step 2.4, repeat steps 2.1 to 2.3 until the speed information of all position line intervals is obtained;
其中,所述速度模型为:Wherein, the speed model is:
v表示为速度信息,λ表示为OCT扫描系统中检测光的波长,Φ1表示为第一相位信息,Φ2表示为第二相位信息,i表示为复审虚部的符号,Im表示为提取复审的虚部,Re表示为提取复数的实部。v is the velocity information, λ is the wavelength of the detected light in the OCT scanning system, Φ 1 is the first phase information, Φ 2 is the second phase information, i is the symbol of the imaginary part of the review, Im is the extraction review The imaginary part of , Re is denoted to extract the real part of the complex number.
进一步,所述扫描区域的尺寸为2.5mm*2.5mm。Further, the size of the scanning area is 2.5mm*2.5mm.
本发明的有益效果是:通过OCT扫描系统对于扫描区域进行有深度的扫描,而且,可以利用鸡蛋胚胎大动脉的血流信息从侧面上得到鸡蛋胚胎的心律。相对于现有技术,该方法得到的心律信息更加完整和准确。The beneficial effect of the present invention is that the scanning area is deeply scanned by the OCT scanning system, and the heart rhythm of the egg embryo can be obtained from the side by using the blood flow information of the aorta of the egg embryo. Compared with the prior art, the heart rhythm information obtained by this method is more complete and accurate.
附图说明Description of drawings
为了更清楚地说明本发明实施例中的技术方案,下面将对实施例描述中所需要使用的附图作简单说明。显然,所描述的附图只是本发明的一部分实施例,而不是全部实施例,本领域的技术人员在不付出创造性劳动的前提下,还可以根据这些附图获得其他设计方案和附图。In order to illustrate the technical solutions in the embodiments of the present invention more clearly, the following briefly describes the accompanying drawings that are used in the description of the embodiments. Obviously, the described drawings are only a part of the embodiments of the present invention, but not all of the embodiments, and those skilled in the art can obtain other design solutions and drawings according to these drawings without creative work.
图1是基于鸡蛋胚胎血流信息的心律测量方法的步骤流程图;Fig. 1 is the step flow chart of the heart rhythm measurement method based on egg embryo blood flow information;
图2是步骤2的子步骤流程图。FIG. 2 is a flow chart of the sub-steps of step 2. FIG.
具体实施方式Detailed ways
以下将结合实施例和附图对本发明的构思、具体结构及产生的技术效果进行清楚、完整地描述,以充分地理解本发明的目的、特征和效果。显然,所描述的实施例只是本发明的一部分实施例,而不是全部实施例,基于本发明的实施例,本领域的技术人员在不付出创造性劳动的前提下所获得的其他实施例,均属于本发明保护的范围。另外,文中所提到的所有联接/连接关系,并非单指构件直接相接,而是指可根据具体实施情况,通过添加或减少联接辅件,来组成更优的联接结构。本发明创造中的各个技术特征,在不互相矛盾冲突的前提下可以交互组合。The concept, specific structure and technical effects of the present invention will be clearly and completely described below with reference to the embodiments and accompanying drawings, so as to fully understand the purpose, characteristics and effects of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, other embodiments obtained by those skilled in the art without creative efforts are all within the scope of The scope of protection of the present invention. In addition, all the coupling/connection relationships mentioned in the text do not mean that the components are directly connected, but refer to a better coupling structure by adding or reducing coupling accessories according to specific implementation conditions. Various technical features in the present invention can be combined interactively on the premise of not contradicting each other.
参考图1和图2,一种基于鸡蛋胚胎血流信息的心律测量方法,该方法基于OCT扫描系统,包括:Referring to Figure 1 and Figure 2, a method for measuring heart rhythm based on egg embryo blood flow information, the method is based on an OCT scanning system, including:
步骤1、将扫描区域横向等分为多个位置线区间;Step 1. Divide the scanning area horizontally into multiple position line intervals;
步骤2、通过OCT扫描系统扫描位置线区间,得到在扫描区域中血流在不同的位置线区间上的速度信息;Step 2. Scan the position line interval by the OCT scanning system, and obtain the velocity information of blood flow on different position line intervals in the scanning area;
步骤3、对所述速度信息进行傅里叶谱变换得到频率-加速度关系曲线,根据频率-加速度关系曲线得到心律。Step 3: Perform Fourier spectral transformation on the speed information to obtain a frequency-acceleration relationship curve, and obtain a heart rhythm according to the frequency-acceleration relationship curve.
步骤2的子步骤包括:The sub-steps of step 2 include:
步骤2.1、通过OCT扫描系统对位置线区间进行两次截面扫描,得到第一截面图和第二截面图;Step 2.1, perform two cross-sectional scans on the position line interval through the OCT scanning system to obtain the first cross-sectional view and the second cross-sectional view;
步骤2.2、对第一截面图进行非节点边界三次样条插值处理后再进行傅里叶变换得到相位信息,所述相位信息记为第一相位信息;对第二截面图进行非节点边界三次样条插值处理后再进行傅里叶变换得到相位信息,所述相位信息记为第二相位信息;Step 2.2: Perform non-node boundary cubic spline interpolation processing on the first cross-sectional image, and then perform Fourier transform to obtain phase information, which is recorded as the first phase information; perform non-node boundary cubic spline sampling on the second cross-sectional image. After the strip interpolation processing, Fourier transform is performed to obtain phase information, and the phase information is denoted as second phase information;
步骤2.3、根据速度模型得到血流在所述位置线区间的速度信息;Step 2.3, obtaining the velocity information of the blood flow in the position line interval according to the velocity model;
步骤2.4、重复步骤2.1至步骤2.3直至得到所有位置线区间的速度信息;Step 2.4, repeat steps 2.1 to 2.3 until the speed information of all position line intervals is obtained;
其中,所述速度模型为:Wherein, the speed model is:
v表示为速度信息,λ表示为OCT扫描系统中检测光的波长,Φ1表示为第一相位信息,Φ2表示为第二相位信息,i表示为复审虚部的符号,Im表示为提取复审的虚部,Re表示为提取复数的实部。v is the velocity information, λ is the wavelength of the detected light in the OCT scanning system, Φ 1 is the first phase information, Φ 2 is the second phase information, i is the symbol of the imaginary part of the review, Im is the extraction review The imaginary part of , Re is denoted to extract the real part of the complex number.
具体的,需要对鸡蛋胚胎的心律进行测量时,通过将扫描区域划定为鸡蛋胚胎大动脉血管所在区域。其中,所述扫描区域的尺寸为2.5mm*2.5mm。先将扫描区域横向划分为多个位置线区间,在本实施例中,则划分为50个位置线区间。然后控制OCT扫描系统对扫描区域进行扫描,其中,扫描的方式为:对每一个位置线区间都扫描两次,每一次扫描均可以得到所在位置线区间的截面图。以对于一个位置线区间为例,第一次扫描得到第一截面图,第二次扫描得到第二截面图。对于OCT扫描系统来讲,得到的截面图中采集的干涉光的光强I为:上述公式记为公式(1),其中,S表示为OCT扫描系统中检测光出光时的光强;Rl与Rr分别表示样品臂和参考臂的光程;k为波矢,k=2π/λ,λ表示为OCT扫描系统中检测光的波长;zl表示为扫描的深度,vl分别表示为扫描位置的血流速度。从公式(1)可以知道截面图中记录了血流速度的信息。Specifically, when the heart rhythm of the egg embryo needs to be measured, the scanning area is defined as the area where the aorta of the egg embryo is located. Wherein, the size of the scanning area is 2.5mm*2.5mm. First, the scanning area is horizontally divided into a plurality of position line sections, and in this embodiment, it is divided into 50 position line sections. Then, the OCT scanning system is controlled to scan the scanning area. The scanning method is as follows: each position line interval is scanned twice, and a cross-sectional view of the position line interval can be obtained in each scan. Taking a position line interval as an example, a first cross-sectional view is obtained by the first scan, and a second cross-sectional view is obtained by the second scan. For the OCT scanning system, the light intensity I of the interference light collected in the obtained cross-sectional view is: The above formula is recorded as formula (1), where S represents the light intensity of the detected light in the OCT scanning system when the light is emitted; R l and R r represent the optical path of the sample arm and the reference arm respectively; k is the wave vector, k=2π /λ, λ represents the wavelength of the detected light in the OCT scanning system; z l represents the scanning depth, and v l represents the blood flow velocity at the scanning position, respectively. From the formula (1), it can be known that the information of the blood flow velocity is recorded in the cross-sectional view.
对于第一截面图和第二截面图分别进行非节点边界三次样条插值处理,其中,非节点边界三次样条插值处理可以对输入图像进行频域分析,得到频域信息和相位信息。故,对第一截面图进行非节点边界三次样条插值处理得到第一截面图的频域信息和相位信息。其中,频域信息对于本实施例没有作用,故舍弃,得到相位信息,记为第一相位信息。同理,对第二截面图进行非节点边界三次样条插值处理得到第二截面图的相位信息,记为第二相位信息。由于血流在流动,因此,第一相位信息和第二相位信息可以反应出血流的流动情况。因此,通过速度模型得到所在位置线区间的速度信息。重复上述操作,直至得到所有位置线区域的速度信息。并对得到的速度信息进行傅里叶谱变换得到频率-加速度关系曲线,根据频率-加速度关系曲线得到心律。由于鸡蛋胚胎的心脏在整个鸡蛋胚胎中处于血流中心位置,因此,扫描区域的各个位置线区域的加速度信息的整体可以反映出鸡蛋胚胎的心律信息。Non-node boundary cubic spline interpolation processing is performed on the first cross-sectional image and the second cross-sectional image respectively, wherein the non-node boundary cubic spline interpolation processing can perform frequency domain analysis on the input image to obtain frequency domain information and phase information. Therefore, the non-node boundary cubic spline interpolation processing is performed on the first cross-sectional view to obtain frequency domain information and phase information of the first cross-sectional view. The frequency domain information has no effect on this embodiment, so it is discarded to obtain phase information, which is recorded as the first phase information. Similarly, non-node boundary cubic spline interpolation processing is performed on the second cross-sectional view to obtain phase information of the second cross-sectional view, which is recorded as second phase information. Since the blood is flowing, the first phase information and the second phase information can reflect the flow of the blood. Therefore, the speed information of the position line section is obtained through the speed model. Repeat the above operation until the speed information of all position line areas is obtained. The obtained velocity information is subjected to Fourier transform to obtain a frequency-acceleration relationship curve, and the heart rhythm is obtained according to the frequency-acceleration relationship curve. Since the heart of the egg embryo is at the center of blood flow in the whole egg embryo, the whole of the acceleration information of each position line area in the scanning area can reflect the heart rhythm information of the egg embryo.
以上对本发明的较佳实施方式进行了具体说明,但本发明创造并不限于所述实施例,熟悉本领域的技术人员在不违背本发明精神的前提下还可做出种种的等同变型或替换,这些等同的变型或替换均包含在本申请权利要求所限定的范围内。The preferred embodiments of the present invention have been specifically described above, but the present invention is not limited to the embodiments, and those skilled in the art can make various equivalent modifications or substitutions without departing from the spirit of the present invention , these equivalent modifications or substitutions are all included within the scope defined by the claims of the present application.
Claims (3)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201911145896.1A CN111297342A (en) | 2019-11-21 | 2019-11-21 | Heart rhythm measuring method based on egg embryo blood flow information |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201911145896.1A CN111297342A (en) | 2019-11-21 | 2019-11-21 | Heart rhythm measuring method based on egg embryo blood flow information |
Publications (1)
Publication Number | Publication Date |
---|---|
CN111297342A true CN111297342A (en) | 2020-06-19 |
Family
ID=71144840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201911145896.1A Pending CN111297342A (en) | 2019-11-21 | 2019-11-21 | Heart rhythm measuring method based on egg embryo blood flow information |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN111297342A (en) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090275812A1 (en) * | 2008-03-04 | 2009-11-05 | Glucolight Corporation | Flowometry in Optical Coherence Tomography for Analyte Level Estimation |
KR20120134477A (en) * | 2011-06-02 | 2012-12-12 | 경북대학교 산학협력단 | Pulse analyzing system using optical coherence tomography for oriental medical and the method |
US20140236002A1 (en) * | 2011-10-17 | 2014-08-21 | University Of Washington Through Its Center For Commercialization | Methods and Systems for Imaging Tissue Motion Using Optical Coherence Tomography |
CN109431484A (en) * | 2018-12-10 | 2019-03-08 | 佛山科学技术学院 | A kind of device and method of the egg Embryo sexing based on heart rate measurement |
-
2019
- 2019-11-21 CN CN201911145896.1A patent/CN111297342A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090275812A1 (en) * | 2008-03-04 | 2009-11-05 | Glucolight Corporation | Flowometry in Optical Coherence Tomography for Analyte Level Estimation |
KR20120134477A (en) * | 2011-06-02 | 2012-12-12 | 경북대학교 산학협력단 | Pulse analyzing system using optical coherence tomography for oriental medical and the method |
US20140236002A1 (en) * | 2011-10-17 | 2014-08-21 | University Of Washington Through Its Center For Commercialization | Methods and Systems for Imaging Tissue Motion Using Optical Coherence Tomography |
CN109431484A (en) * | 2018-12-10 | 2019-03-08 | 佛山科学技术学院 | A kind of device and method of the egg Embryo sexing based on heart rate measurement |
Non-Patent Citations (2)
Title |
---|
IRINA V. LARINA 等: "Live imaging of blood flow in mammalian embryos using Doppler swept-source optical coherence tomography", 《JOURNAL OF BIOMEDICAL OPTICS》 * |
窦世丹: "基于光学相干层析成像的胚胎心脏血流参数研究", 《中国优秀博硕士学位论文全文数据库(硕士) 医药卫生科技辑》 * |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5788174B2 (en) | Real-time spectral domain optical coherence tomography using distributed acquisition and processing | |
Yang et al. | EDA-Net: dense aggregation of deep and shallow information achieves quantitative photoacoustic blood oxygenation imaging deep in human breast | |
JP4454030B2 (en) | Image processing method for three-dimensional optical tomographic image | |
EP1910997B1 (en) | Methods, systems and computer program for 3d-registration of three dimensional data sets obtained by preferably optical coherence tomography based on the alignment of projection images or fundus images, respectively | |
US9858668B2 (en) | Guidewire artifact removal in images | |
US12249052B2 (en) | Correction of flow projection artifacts in octa volumes using neural networks | |
EP3494880A1 (en) | Automatic stent detection | |
US20140099011A1 (en) | Removal of a-scan streaking artifact | |
CN105342568B (en) | The optical coherence angiographic method and system of joint phase and amplitude | |
EP2903532A2 (en) | Methods and systems for establishing parameters, playback, and artifact removal three-dimensional imaging | |
CN107862724B (en) | Improved microvascular blood flow imaging method | |
US9471975B2 (en) | Methods, systems and computer program products for dynamic optical histology using optical coherence tomography | |
WO2014100291A1 (en) | System and method for imaging subsurface of specimen | |
Nogueira et al. | Tissue biomolecular and microstructure profiles in optical colorectal cancer delineation | |
KR100982619B1 (en) | Non-invasive early diagnosis method and device of fruit disease | |
KR101442708B1 (en) | Optical coherence tomography for processing three-dimensional oct data using 64 bit based dynamic memory allocation method | |
Alexandrov et al. | Spatial frequency domain correlation mapping optical coherence tomography for nanoscale structural characterization | |
CN105654497B (en) | A kind of time reversal method for reconstructing of intravascular photoacoustic image | |
Sun et al. | Real-time optical-resolution photoacoustic endoscope | |
CN111297342A (en) | Heart rhythm measuring method based on egg embryo blood flow information | |
Chen et al. | Cube data correlation-based imaging of small blood vessels | |
US11779277B2 (en) | Systems and methods for endovascular device detection and apposition measurement | |
Elahi et al. | Complex regression Doppler optical coherence tomography | |
Smirni et al. | In-vivo assessment of microvascular functional dynamics by combination of cmOCT and wavelet transform | |
JP2018102359A (en) | Processing apparatus and processing method |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB02 | Change of applicant information |
Country or region after: China Address after: No.33 Guangyun Road, Shishan town, Nanhai District, Foshan City, Guangdong Province Applicant after: Foshan University Address before: No.33 Guangyun Road, Shishan town, Nanhai District, Foshan City, Guangdong Province Applicant before: FOSHAN University Country or region before: China |
|
CB02 | Change of applicant information |