CN1112002A - Oral medicine for treatment of mastopathy - Google Patents
Oral medicine for treatment of mastopathy Download PDFInfo
- Publication number
- CN1112002A CN1112002A CN 94113028 CN94113028A CN1112002A CN 1112002 A CN1112002 A CN 1112002A CN 94113028 CN94113028 CN 94113028 CN 94113028 A CN94113028 A CN 94113028A CN 1112002 A CN1112002 A CN 1112002A
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- Prior art keywords
- radix
- medicine
- rhizoma
- carapax
- treatment
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- Pending
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- 239000003814 drug Substances 0.000 title claims abstract description 21
- 208000030270 breast disease Diseases 0.000 title claims abstract description 5
- 239000004615 ingredient Substances 0.000 claims description 11
- 108010052008 colla corii asini Proteins 0.000 claims description 6
- 241000717739 Boswellia sacra Species 0.000 claims description 5
- 239000004863 Frankincense Substances 0.000 claims description 5
- 241001057584 Myrrha Species 0.000 claims description 5
- 230000002792 vascular Effects 0.000 claims description 5
- 241000218176 Corydalis Species 0.000 claims description 4
- 229940079593 drug Drugs 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 4
- 210000000582 semen Anatomy 0.000 claims description 4
- 241000628997 Flos Species 0.000 claims description 3
- 241000283956 Manis Species 0.000 claims description 2
- 238000009835 boiling Methods 0.000 claims description 2
- 239000002552 dosage form Substances 0.000 claims description 2
- 229940126701 oral medication Drugs 0.000 claims description 2
- 239000006187 pill Substances 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 239000007909 solid dosage form Substances 0.000 claims 1
- 239000000463 material Substances 0.000 abstract description 2
- 108010010803 Gelatin Proteins 0.000 abstract 1
- 241000270666 Testudines Species 0.000 abstract 1
- 241000270708 Testudinidae Species 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 239000008273 gelatin Substances 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 210000005075 mammary gland Anatomy 0.000 description 7
- 206010001233 Adenoma benign Diseases 0.000 description 6
- 208000007659 Fibroadenoma Diseases 0.000 description 6
- 239000008280 blood Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 210000000481 breast Anatomy 0.000 description 6
- 201000003149 breast fibroadenoma Diseases 0.000 description 6
- 210000003734 kidney Anatomy 0.000 description 6
- 201000010099 disease Diseases 0.000 description 4
- 210000004185 liver Anatomy 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 230000000994 depressogenic effect Effects 0.000 description 2
- 208000035475 disorder Diseases 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 208000026435 phlegm Diseases 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 description 1
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 206010010356 Congenital anomaly Diseases 0.000 description 1
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 241001530126 Scrophularia Species 0.000 description 1
- 229960001230 asparagine Drugs 0.000 description 1
- 235000009582 asparagine Nutrition 0.000 description 1
- 230000000680 avirulence Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 201000008275 breast carcinoma Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The oral medicine for curing mastopathy is prepared from more than 20 Chinese-medicinal materials such as tortoise plastron, turtle shell, donkey-hide gelatin, etc.
Description
What the present invention relates to is a kind of oral drugs that are used for the treatment of mastopathy of being made up of natural medicinal ingredient.
" nodules of the breast " that mammary gland tumor such as cyclomastopathy, mammary gland fibroadenoma is referred to as in traditional Chinese medicine is the common and multiple disease that a class mainly betides the women.The oral medicine commonly used of treatment at present has XIAOHE PIAN, asparagine sheet, XIAOJIN DAN etc.Clinical practice finds that the effect that many patients take behind these medicines is unsatisfactory, even does not almost have positive effect.Other has the medicine of some document announcements, and what introduced as Chinese patent 91112645.7 and 93100596.5 etc. all is the medicine that can be used for treating breast carcinoma, is not to be applicable to above-mentioned " nodules of the breast " class treatment of diseases.
The object of the present invention is to provide a kind of medicine that is used for the treatment of " nodules of the breast " class diseases such as cyclomastopathy, mammary gland fibroadenoma.
Effective ingredient of the present invention is natural medicinal ingredient, and the weight portion ratio relation of its effective ingredient is: Carapax et Plastrum Testudinis 1.4～2.6, Carapax Trionycis 1.4～2.6, Colla Corii Asini 1.4～2.6, Squama Manis 1.4～2.6, Concha Ostreae 1.4～2.6, Fructus Foeniculi 0.7～1.3, Pericarpium Citri Reticulatae 0.7～1.3, vascular aurantii 1.4～2.6, Fructus Citri tangerinae nuclear 2.8～5.2, Herba Taraxaci 8～16, Spica Prunellae 8～16, Radix Bupleuri 2.8～5.2, Radix Angelicae Sinensis 5.6～10.4, Radix Paeoniae Rubra 2.8～5.2, Rhizoma Chuanxiong 2.8～5.2, rhizoma sparganic 1.4～2.6, Rhizoma Curcumae 1.4～2.6, Rhizoma Corydalis 2.8～5.2, the Radix Rehmanniae 2.8～5.2, Semen Persicae 2.8～5.2, Flos Carthami 2.8～5.2, Olibanum 1.4～2.6, Myrrha 1.4～2.6, Bulbus Fritillariae Thunbergii 2.8～5.2, Radix Curcumae 2.8～5.2, wine army 2.8～5.2, Radix Salviae Miltiorrhizae 2.8～5.2, Radix Scrophulariae 2.8～5.2.
By observation and analysis to " nodules of the breast " class disease origin cause of formation, unbalance by the kidney yin kidney yang that the Chinese medicine viewpoint can be divided into due to congenital or/and day after tomorrow of the reason, or due to dash and appoint a disorder of QI and blood, or owing to several reasons such as depression of liver-QI, Liver and kidney do not conform to.According to this etiological analysis, in said medicine of the present invention,, regulate equilibrium between yin and yang with Carapax et Plastrum Testudinis, Carapax Trionycis nourishing Kidney-Yin; Colla Corii Asini transfers blood to enrich blood, and appoints with Gu Chong; Fructus Foeniculi, Radix Bupleuri, Pericarpium Citri Reticulatae, Radix Curcumae, Rhizoma Corydalis are in order to the depressed liver-energy dispersing and QI regulating pain relieving; Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Semen Persicae, Olibanum, Myrrha, wine army are used for blood circulation promoting and blood stasis dispelling; Herba Taraxaci, Fructus Citri tangerinae nuclear, vascular aurantii, Bulbus Fritillariae Thunbergii, Spica Prunellae can follow the dissipating phlegm and resolving masses of Liver Channel collateral dredging; Squama Manis, Concha Ostreae, rhizoma sparganic, Rhizoma Curcumae have the effect of broken knot and softening the hard mass.Medicine composition and function thereof are understood that thus, medicine of the present invention has changed traditional treatment " nodules of the breast " only based on the method for treatment mechanism of depressed liver-energy dispersing and QI regulating, resolving phlegm and softening hard masses, but it is unbalance according to the kidney yin kidney yang, dash the origin cause of formation of appointing disorder of QI and blood, it is the treatment prerequisite that proposition is transferred towards beneficial blood with reinforcing Gu Yuan, has emphasis ground to propose to be basic treatment policy with " leading to " and " loosing ".But by women's physiology and the decision of body characteristics, its property of medicine logical, that loose is unsuitable high again excessively violent, so used tonneau composition belongs to slow logical slow diffusing product mostly, shows slightly high violent composition on a small quantity, and is also lighter as consumptions such as wine army, rhizoma sparganic, Rhizoma Curcumae, Olibanum, Myrrhas.The special unique distinction that proposes to break through especially as the principal agent of nourishing kidney easing the affected liver traditional treatment mechanism in the medicine with Carapax et Plastrum Testudinis, Carapax Trionycis, Colla Corii Asini.
The peroral dosage form of medicine of the present invention is selected general no specific (special) requirements, but according to general practical experience and experimental result, convenient with solid dosage formss such as sheet, ball, capsules, and effect is better, and effect is lasting.Particularly according to character, the effect of each medicinal ingredient, taking to handle respectively the back remix will have better effect.For example, with respectively 4 parts of the crude drug medicated powder of medicinal ingredients such as each 1 part of Carapax et Plastrum Testudinis, Carapax Trionycis, Colla Corii Asini, Squama Manis, Concha Ostreae, vascular aurantii each 2 parts (weight) and Fructus Foeniculi, Pericarpium Citri Reticulatae and Fructus Citri tangerinae nuclear, Radix Bupleuri, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Rhizoma Corydalis, the Radix Rehmanniae, Semen Persicae, Flos Carthami, Bulbus Fritillariae Thunbergii, Radix Curcumae, wine army, Radix Salviae Miltiorrhizae, Radix Scrophulariaes, respectively 2 parts of rhizoma sparganic, Rhizoma Curcumae, Olibanum, Myrrhas, 8 parts of Radix Angelicae Sinensis, and the water boiling concentration thing (as stiff paste) of all the other medicinal ingredients such as each 12 parts of Herba Taraxacis, Spica Prunellae mixes, and makes solid dosage formss such as ball, sheet, capsule according to a conventional method and uses.Practice shows that said each medicinal ingredient consumption changes in the scope on this basis ± 30%, generally can not produce tangible influence to therapeutic effect here.By documents and materials as can be known, these medicinal ingredients are the thing of avirulence, have not also observed bad in actual the use and the toxic and side effects generation.
With the above-mentioned prepared pill of method of enumerating is that example has been made a large amount of clinical experiment observation of curative effect, and the efficacy result of " nodules of the breast " such as cyclomastopathy, mammary gland fibroadenoma is seen Table 1.Curative effect determinate standard wherein is:
Cyclomastopathy: the complete obiteration of recovery from illness-enclosed mass, pain disappears
Produce effects-enclosed mass narrows down in the 0.5cm, and pain disappears
Improvement-enclosed mass narrows down to 1cm and disappears with interior, pain,
Invalid-enclosed mass does not dwindle, and pain does not have obviously and alleviates.
Mammary gland fibroadenoma: recovery from illness-enclosed mass complete obiteration
Produce effects-enclosed mass narrows down in the 0.5cm
Improvement-enclosed mass narrows down in the 1cm
Invalid-enclosed mass size does not have change
As can be seen the total effective rate of cyclomastopathy being reached 97.8% by table 1 result, is 81.5% to the total effective rate of mammary gland fibroadenoma disease, and effect is satisfied.
Table 1
| Recovery from illness | Produce effects | Take a turn for the better | Effectively total | Invalid | ||||||
| The example number | ％ | The example number | ％ | The example number | ％ | The example number | ％ | The example number | ％ | |
| Cyclomastopathy | 845 | 87.2 | 64 | 6.6 | 39 | 4.0 | 948 | 97.8 | 21 | 2.2 |
| Mammary gland fibroadenoma | 88 | 50.9 | 27 | 15.6 | 26 | 15.0 | 141 | 81.5 | 32 | 18.5 |
Claims (3)
1, a kind ofly form the oral drugs that are used for the treatment of mastopathy, it is characterized in that effective ingredient is (weight portion) by natural medicinal ingredient:
Carapax et Plastrum Testudinis 1.4～2.6, Carapax Trionycis 1.4～2.6, Colla Corii Asini 1.4～2.6,
Squama Manis 1.4～2.6, Concha Ostreae 1.4～2.6, Fructus Foeniculi 0.7～1.3,
Pericarpium Citri Reticulatae 0.7～1.3, vascular aurantii 1.4～2.6, Fructus Citri tangerinae nuclear 2.8～5.2,
Herba Taraxaci 8～16, Spica Prunellae 8～16, Radix Bupleuri 2.8～5.2,
Radix Angelicae Sinensis 5.6～10.4, Radix Paeoniae Rubra 2.8～5.2, Rhizoma Chuanxiong 2.8～5.2,
Rhizoma sparganic 1.4～2.6, Rhizoma Curcumae 1.4～2.6, Rhizoma Corydalis 2.8～5.2,
The Radix Rehmanniae 2.8～5.2, Semen Persicae 2.8～5.2, Flos Carthami 2.8～5.2, Olibanum 1.4～2.6,
Myrrha 1.4～2.6, Bulbus Fritillariae Thunbergii 2.8～5.2,
Radix Curcumae 2.8～5.2, wine army 2.8～5.2, Radix Salviae Miltiorrhizae 2.8～5.2,
Radix Scrophulariae 2.8～5.2.
2, medicine as claimed in claim 1 is characterized in that it is the solid dosage form that the water boiling concentration thing of the crude drug medicated powder of Carapax et Plastrum Testudinis, Carapax Trionycis, Colla Corii Asini, Squama Manis, Concha Ostreae, Fructus Foeniculi, Pericarpium Citri Reticulatae and vascular aurantii in being made up of medicine and all the other compositions mixes.
3, medicine as claimed in claim 2 is characterized in that said dosage form is a pill.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 94113028 CN1112002A (en) | 1994-12-14 | 1994-12-14 | Oral medicine for treatment of mastopathy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 94113028 CN1112002A (en) | 1994-12-14 | 1994-12-14 | Oral medicine for treatment of mastopathy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1112002A true CN1112002A (en) | 1995-11-22 |
Family
ID=5036491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 94113028 Pending CN1112002A (en) | 1994-12-14 | 1994-12-14 | Oral medicine for treatment of mastopathy |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1112002A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1315525C (en) * | 2005-05-11 | 2007-05-16 | 陈志强 | Chinese traditional medicine for treating breast disease and preparing technique |
| CN102151325A (en) * | 2011-04-13 | 2011-08-17 | 苑学 | Traditional Chinese medicine for treating breast diseases |
-
1994
- 1994-12-14 CN CN 94113028 patent/CN1112002A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1315525C (en) * | 2005-05-11 | 2007-05-16 | 陈志强 | Chinese traditional medicine for treating breast disease and preparing technique |
| CN102151325A (en) * | 2011-04-13 | 2011-08-17 | 苑学 | Traditional Chinese medicine for treating breast diseases |
| CN102151325B (en) * | 2011-04-13 | 2012-07-04 | 苑学 | Traditional Chinese medicine for treating breast diseases |
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| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |