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CN111175076B - Liquid collecting device - Google Patents

Liquid collecting device Download PDF

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Publication number
CN111175076B
CN111175076B CN201811335495.8A CN201811335495A CN111175076B CN 111175076 B CN111175076 B CN 111175076B CN 201811335495 A CN201811335495 A CN 201811335495A CN 111175076 B CN111175076 B CN 111175076B
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Prior art keywords
absorber
layer absorber
liquid
sampling rod
inner layer
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CN201811335495.8A
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CN111175076A (en
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请求不公布姓名
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Microporous Technology (ningbo) Ltd
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Microporous Technology (ningbo) Ltd
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Priority to CN201811335495.8A priority Critical patent/CN111175076B/en
Priority to PCT/CN2019/076603 priority patent/WO2020093629A1/en
Publication of CN111175076A publication Critical patent/CN111175076A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/10Devices for withdrawing samples in the liquid or fluent state

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Hydrology & Water Resources (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention relates to a liquid collecting device, which is provided with a handle, a sampling rod and an absorber coated on the peripheral wall of the sampling rod, wherein the absorber comprises an outer layer absorber and an inner layer absorber, the inner peripheral wall of the outer layer absorber and the outer peripheral wall of the inner layer absorber are mutually bonded, and the density of the outer layer absorber is less than that of the inner layer absorber; the inner layer absorber is provided with an axial jack which can radially stretch and retract. The liquid collecting device has the advantages of simple structure, easy production and assembly, convenient use, easy use of collected liquid samples for subsequent testing and wide application in various medical inspection places.

Description

Liquid collecting device
Technical Field
The invention relates to a liquid collection device, in particular to a liquid collection device used in the fields of medical inspection and drug detection.
Background
In the fields of medical testing and drug testing, testing of blood, urine and saliva is common. The collection of a liquid sample to be analyzed is a link in the detection process. One commonly used method for collecting liquid is to place a liquid absorber in the collected site, and take out the liquid absorber after a certain period of time for subsequent testing. For ease of handling, the prior art has used adhesives to secure the liquid absorbent to a sheet at the front end of a handle. The method has low efficiency and high cost, and the absorber is easy to fall off in the using process.
The utility model provides a liquid collection system among the prior art, the device includes the funnel, and the funnel below is connected with detachable outer tube, and the outer tube endotheca is equipped with the inner tube that the bottom set up, opening down, has deposited the preservation liquid in the inner tube, and the space between outer tube and the inner tube is outer cavity, and outer cavity communicates with the funnel, and the inner tube links to each other with the funnel, and outer tube bottom is provided with and is used for the confined step of inner tube mouth of pipe. When the outer tube and the funnel are screwed tightly, the inner tube and the outer chamber are isolated in a sealing way, so that the preservation solution cannot leak out before the device is not used; when the outer tube is screwed off the funnel, the inner tube is dredged with the outer chamber, so that the preservation solution in the inner tube is ensured to be mixed with the liquid in the outer chamber, the liquid is preserved for a long time, and the quality of a sample is further ensured. The device ensures that the preservation solution flows out from the bottom of the inner tube to be mixed with the liquid, and avoids the pollution generated in the process of adding from the outside in the prior art. However, the liquid collecting device has a complex structure, which is not beneficial to manufacturing production.
Another saliva collection device in the prior art comprises a liquid storage pipe and a cover body, wherein the liquid storage pipe and the cover body can form an internal liquid storage space after being disassembled and connected, an isolating film is further arranged in the liquid storage space, the liquid storage space is divided into two parts which are independent from each other by the isolating film, a puncturing device is arranged in the cover body and used for puncturing the isolating film after the liquid storage pipe and the cover body are disassembled and connected. The liquid storage tube is made of transparent material or opaque material. The liquid collecting device has more parts and is inconvenient to use.
Disclosure of Invention
In order to solve the technical problems in the prior art, the invention discloses a liquid collecting device, which is provided with a handle, a sampling rod and an absorber coated on the peripheral wall of the sampling rod, wherein the absorber comprises an outer layer absorber and an inner layer absorber, the inner peripheral wall of the outer layer absorber and the outer peripheral wall of the inner layer absorber are mutually bonded, and the density of the outer layer absorber is less than that of the inner layer absorber; the inner layer absorber is provided with an axial jack which can radially stretch and retract.
Further, the outer layer absorbent has a density of 0.035 to 0.20 g/cm 3 and the inner layer absorbent has a density of 0.15 to 0.45 g/cm 3.
Further, the wall thickness of the inner layer absorber is 0.2 mm to 3.5 mm.
Further, both the outer absorbent and the inner absorbent are made of bicomponent fiber bonds.
Further, the axial compressive strength of the absorber is greater than the radial compressive strength.
Further, the liquid collection device also comprises an upper baffle plate and a lower baffle plate which are arranged at two ends of the sampling rod, and the upper baffle plate is fixedly connected with the end part of the handle.
Further, the cross-sectional area of the lower baffle decreases from top to bottom, and the maximum cross-sectional area of the lower baffle is greater than the inner diameter of the insertion hole and less than the maximum expanded inner diameter of the insertion hole.
Further, the handle, the upper baffle, the sampling rod and the lower baffle are integrally formed.
Further, the cross section of the lower baffle is circular.
Further, a liquid collection indicating component is arranged between the absorber and the upper baffle.
As described above, the liquid collection device according to the present invention can collect the liquid to be tested conveniently and rapidly, and can easily use the collected liquid sample for subsequent testing.
In order to make the above-mentioned aspects of the present invention more comprehensible, preferred embodiments accompanied with figures are described in detail below.
Drawings
The invention will now be described with reference to the accompanying drawings.
FIG. 1 is a schematic cross-sectional view of a liquid collection device according to a first embodiment of the present invention;
FIG. 2 is a schematic cross-sectional view of a liquid collection device according to a second embodiment of the present invention;
FIG. 3 is a schematic cross-sectional view of a liquid collection device according to a third embodiment of the present invention;
FIG. 4 is a schematic view of a liquid collection container associated with a liquid collection device according to a third embodiment of the present invention;
fig. 5 is a schematic structural view of a liquid collecting device according to a fourth embodiment of the present invention;
Fig. 6 is a schematic view of section A-A of fig. 5.
Detailed Description
The following specific examples are presented to illustrate the embodiments of the present invention and to enable those skilled in the art to make and use the present invention.
In the present invention, the lower end or front end in the drawings refers to one end of the lower baffle plate, and the upper end or rear end refers to one end of the handle.
The exemplary embodiments of the present invention will now be described with reference to the accompanying drawings, however, the present invention may be embodied in many different forms and is not limited to the examples described herein, which are provided to fully and completely disclose the present invention and fully convey the scope of the invention to those skilled in the art. The terminology used in the exemplary embodiments illustrated in the accompanying drawings is not intended to be limiting of the invention. In the drawings, like elements/components are referred to by like reference numerals.
Unless otherwise indicated, terms used herein, including technical and scientific terms, have the same meaning as commonly understood by one of ordinary skill in the art. In addition, it will be understood that terms defined in commonly used dictionaries should be interpreted as having a meaning that is consistent with their meaning in the context of the relevant art and will not be interpreted in an idealized or overly formal sense.
First embodiment
Fig. 1 is a schematic cross-sectional view of a liquid collection device according to a first embodiment of the present invention. As shown in fig. 1, the liquid collecting device according to the first embodiment of the present invention has a handle 1, a sampling rod 13, and an absorber 2 coated on the outer peripheral wall of the sampling rod 13, the absorber 2 including an outer layer absorber 21 and an inner layer absorber 22, the inner peripheral wall of the outer layer absorber 21 and the outer peripheral wall of the inner layer absorber 22 being bonded to each other, the density of the outer layer absorber 21 being smaller than the density of the inner layer absorber 22; the inner absorbent body 22 has radially stretchable axial insertion holes 23.
The handle 1 in the present invention is generally cylindrical and serves to provide a gripping area for the sampler to operate the liquid collection device. Of course, the handle 1 may be provided in other three-dimensional shapes for easy gripping, such as a square column.
The sampling rod 13 in the invention is preferably a cylinder, and the peripheral wall of the sampling rod is coated with the absorber 2, and can be directly or indirectly fixedly connected with the end part of the handle 1. The sampling rod 13 may be injection molded from a plastic such as polypropylene or polymethyl methacrylate. In particular, the handle 1 and the sampling rod 13 may be integrally injection molded to reduce the number of assembled parts and simplify the assembly process.
The main function of the outer absorbent body 21 according to the invention is to absorb the liquid sample and release the liquid in a subsequent test. Suitable outer absorbent densities are in the range of 0.035-0.20 g/cm 3, too high a density and too low a porosity of the outer absorbent 21 may result in insufficient liquid absorption, and a high density outer absorbent 21 may have a higher hardness and may cause discomfort to the person being sampled. When the density of the outer absorbent body 21 is too low, the outer absorbent body 21 is difficult to manufacture, and insufficient capillary force of the outer absorbent body 21 with too low a density may cause difficulty in sampling. The outer absorbent 21 is soft and has sufficient capillary force, has a high sampling speed and a large collection amount, and can easily release the collected liquid sample after radial extrusion, by selecting a proper density according to application requirements.
The main function of the inner absorbent body 22 according to the invention is to support the softer outer absorbent body 21 and to form a radially telescopic axial insertion hole 23, which allows easy assembly of the absorbent body 2 and other components of the liquid acquisition device, greatly reducing the manufacturing costs and improving the reliability of the product. The axial insertion hole 23 which can radially stretch can radially expand under the action of external force so as to increase the inner diameter of the insertion hole 23 and facilitate the insertion and assembly of the sampling rod 13. After the sampling rod 13 is assembled in place, the receptacle 23 may be radially retracted back to tightly cover the peripheral wall of the sampling rod 13, forming a tight fit.
The inner absorbent layer 22 has a density of 0.15-0.45 grams/cm 3. If the density of the inner absorbent member 22 is too low, the strength is insufficient, and the absorbent member is easily detached from the sampling rod 13. Too high a density of the inner absorbent layer 22 can result in too low a radial stretch of the receptacles to be assembled. The inner absorbent body 22 has a wall thickness of 0.2-3.5mm, and a smaller absorbent body 2 is suitable because the device is mainly used for collecting liquid samples of parts of the human body such as the mouth, nasal cavity, cervix, vagina, etc. The thinner inner layer absorber 22 wall thickness facilitates reducing the absorber diameter, facilitating the fabrication of smaller liquid acquisition devices; the larger wall thickness of the inner absorbent 22 is advantageous for increasing the strength of the inner absorbent 22, and is suitable for manufacturing applications requiring higher strength of the inner absorbent 22, such as liquid collecting devices that need to extrude the liquid collected in the absorbent 2.
According to the liquid collecting device of the present invention, the absorber 2 comprises the inner layer absorber 22 with higher density and the outer layer absorber 21 with lower density, which are both made of two-component fiber bonding, preferably two-component fiber with sheath-core structure or eccentric-core structure, such as polyethylene/polypropylene fiber, polyethylene/polyester fiber, etc., and the chemically inert polyethylene is used as the sheath of the fiber, so that the absorption of the detected component in the liquid sample can be reduced, and the sensitivity of the subsequent test can be improved. The inner wall of the outer layer absorber 21 and the outer wall of the inner layer absorber 22 are bonded to each other, and the outer layer absorber can be prevented from falling off during assembly or use.
According to the liquid collecting device of the present invention, the axial compression strength of the absorber 2 is greater than the radial compression strength. With this structure, the liquid collected in the absorber 2 can be squeezed out in a radially compressed manner.
The liquid collecting device also comprises an upper baffle 12 and a lower baffle 14 which are arranged at two ends of the sampling rod 13, and the upper baffle 12 is fixedly connected with the end part of the handle 1.
The cross-sectional area of the lower baffle 14 decreases from top to bottom, and the maximum cross-sectional area of the lower baffle 14 is greater than the inner diameter of the receptacle 23 and less than the maximum expanded inner diameter of the receptacle 23.
In order to simplify the assembly process and reduce the cost, the handle 1, the sampling rod 13, the upper baffle 12 and the lower baffle 14 are integrally formed in this embodiment, and preferably injection molding is adopted. The absorber 2 is used for absorbing liquid to be detected, and the absorber 2 is provided with an axial jack which can be radially stretched, and the cross section of the lower baffle 14 decreases from top to bottom, so that the maximum cross section of the lower baffle 14 is larger than the inner diameter of the jack 23 and smaller than the maximum expanded inner diameter of the jack 23. Preferably, the cross section of the lower end of the lower baffle 14 is set smaller than the cross section of the insertion hole 23 in the inner layer absorber 22, when the lower baffle 14 is inserted into the insertion hole 23 of the inner layer absorber 22, the insertion hole 23 is radially opened, so that the lower portions of the lower baffle 14 and the sampling rod 13 can smoothly pass through the insertion hole 23, and after the lower baffle 14 completely passes through the insertion hole 23, the insertion hole 23 is radially retracted. Since the maximum cross section of the lower baffle 14 is larger than the cross section of the insertion hole 23, the absorber 2 cannot escape from the lower baffle. After the liquid sample is sampled, the liquid sample can be directly used for subsequent testing.
The cross section of the lower baffle 14 is preferably circular or a polygon of approximately circular shape. The longitudinal section of the lower baffle 14 is preferably trapezoidal, circular arc or the like. In the present embodiment, the lower baffle 14 is provided with a trapezoidal longitudinal section.
Second embodiment
Fig. 2 is a schematic cross-sectional view of a liquid collection device according to a second embodiment of the present invention. The present embodiment is similar to the first embodiment in structure, and the same parts as those of the first embodiment are not described in detail in the description of the present embodiment.
As shown in fig. 2, in the liquid collecting device of the present embodiment, the front end of the absorber 2 is formed in a spherical crown shape, the wall thickness of the inner layer absorber 22 is 0.2mm, and if the strength of the inner layer absorber 22 needs to be increased, the wall thickness of the inner layer absorber 22 can be increased appropriately. The liquid collection device of the embodiment is suitable for collecting samples at human body parts with smaller space and more sensitivity. Such as nasal, cervical, vaginal, etc.
In the liquid collecting device of this embodiment, an indicating component 3, such as a protonic color-changing test paper, is disposed between the upper end of the absorber 2 and the upper baffle 12, so that the collecting state of the absorber on the liquid sample can be observed in real time during sampling, so as to be convenient for judging whether the sample collection is completed.
In the present embodiment, the longitudinal section of the lower baffle 14 is provided in a circular arc shape.
Third embodiment
Fig. 3 is a schematic cross-sectional view of a liquid collection device according to a third embodiment of the present invention. The present embodiment is similar to the first embodiment in structure, and the same parts as those of the first embodiment are not described in detail in the description of the present embodiment.
As shown in fig. 3, this embodiment is similar to the first embodiment. The liquid collection device of this embodiment is used for collecting saliva in the oral cavity for drug abuse detection, the density of the outer layer absorber 21 is about 0.08 g/cm 3, the density of the inner layer absorber 22 is 0.35 g/cm 3, and the wall thickness is 1.5mm, so that the inner layer absorber 22 has higher strength. In the present embodiment, the lower baffle 14 is provided with a trapezoidal longitudinal section.
In the present embodiment, in the process of manufacturing the absorber 2, the fiber arrangement direction may be controlled so that the axial compressive strength of the absorber 2 is greater than the radial compressive strength.
Fig. 4 is a schematic structural view of a liquid collecting container which is matched with a liquid collecting device of a third embodiment of the present invention. As shown in fig. 4, when the absorber 2 absorbs enough liquid, a mating liquid collecting container 4 as shown in fig. 4 is inserted, and the handle 1 is pressed down so that the absorber 2 is radially compressed, thereby squeezing the liquid in the absorber 2 into the liquid collecting container 4.
In particular, as shown in fig. 4, the liquid collecting container 4 used in cooperation with the liquid collecting apparatus shown in fig. 3 includes a liquid collecting chamber 41, and a compressing portion for radially compressing the absorber 2 disposed in the liquid collecting chamber 41. The compression portion includes a conical inlet 42, a radial compression chamber 43 provided at a lower portion of the inlet 42, and a liquid discharge port 44 provided near a boundary between the inlet 42 and the radial compression chamber 43. The liquid discharge port 44 communicates with the liquid collection chamber 41. The diameter of the upper baffle plate 2 is basically equal to the diameter of the absorber 2 after being fully radially compressed, the inner diameter of the radial compression cavity 43 is slightly larger than the diameter of the absorber 2 after being fully radially compressed, and the maximum cross-sectional diameter of the lower baffle plate 14 is smaller than the diameter of the absorber 2 after being fully radially compressed. The upper baffle 12 is provided with a large strength so as to press the absorber 2 into the liquid collection container 4.
When the absorbent body 2 absorbs sufficient liquid, the handle 1 presses the absorbent body 2 into the conical inlet 42 of the liquid collection container 4, and the absorbent body 2 gradually compresses radially until it is pressed into the radial compression chamber 43. In the radial compression chamber 43, the absorber 2 is sufficiently radially compressed, and the absorbed liquid is sufficiently released and flows into the liquid collection chamber 41 through the liquid discharge port 44, thereby completing the liquid collection work. The collected liquid sample was used for subsequent detection.
Fourth embodiment
Fig. 5 is a schematic cross-sectional view of a liquid collection device according to a fourth embodiment of the present invention. The present embodiment is similar to the first embodiment in structure, and the same parts as those of the first embodiment will not be repeated in the description of the present embodiment
As shown in fig. 5, this embodiment is similar to the first embodiment. The liquid collection device of this embodiment is used for collecting saliva in the oral cavity for detecting diseases such as acquired immunodeficiency, and the absorber needs to rub the gum part to obtain part of epithelial cells during saliva collection, for example, detecting aids by oral sampling.
The density of the outer absorbent body 21 was 0.20 g/cm 3, the density of the inner absorbent body 22 was 0.45 g/cm 3, and the wall thickness was set to 2mm-3.5mm, so that the absorbent body had a high strength. In this embodiment, the lower end of the thickened handle 1 also serves as the upper baffle 12, and the absorber 2 is fixed together with the circular arc-shaped lower baffle 14.
Fig. 6 is a schematic view of section A-A of fig. 5. In this embodiment, the cross-sectional profile of the outer absorbent member 21 is toothed to increase the effect of obtaining epithelial cells when rubbing against gums.
In summary, the liquid collecting device according to the present invention has a simple structure, is convenient to manufacture, and uses the radial telescopic axial insertion holes 23 formed by bonding the bicomponent fibers provided in the absorber 2 to fix the absorber 2 between the upper baffle 12 and the lower baffle 14, thereby greatly reducing the manufacturing cost and ensuring that the absorber does not fall off during use. The liquid collecting device can be widely applied to various medical detection occasions, and has good social significance and economic value.
The above embodiments are merely illustrative of the principles of the present invention and its effectiveness, and are not intended to limit the invention. Modifications and variations may be made to the above-described embodiments by those skilled in the art without departing from the spirit and scope of the invention. Accordingly, it is intended that all equivalent modifications and variations be included in the scope of the following claims be embraced by the claims, which are intended to be included within the scope of the present invention.

Claims (7)

1. A liquid collecting device is provided with a handle (1), a sampling rod (13) and an absorber (2) coated on the peripheral wall of the sampling rod (13), and is characterized in that,
The absorber (2) comprises an outer layer absorber (21) and an inner layer absorber (22), wherein the inner peripheral wall of the outer layer absorber (21) and the outer peripheral wall of the inner layer absorber (22) are bonded with each other, and the density of the outer layer absorber (21) is smaller than that of the inner layer absorber (22);
The inner layer absorber (22) is provided with an axial jack (23) which can radially stretch and retract;
The density of the outer layer absorber (21) is 0.035-0.20 g/cm 3, and the density of the inner layer absorber (22) is 0.15-0.45 g/cm 3;
The outer layer absorber (21) and the inner layer absorber (22) are both made of bicomponent fiber bonding;
The axial compression strength of the absorber (2) is greater than the radial compression strength;
The axial insertion hole (23) which can radially stretch can radially expand under the action of external force so as to facilitate the insertion and assembly of the sampling rod (13) after the inner diameter of the axial insertion hole (23) is increased; after the sampling rod (13) is assembled in place, the axial insertion hole (23) can be radially contracted and reset, so that the peripheral wall of the sampling rod (13) is tightly covered, and a tight assembly is formed.
2. The liquid acquisition device according to claim 1, wherein the inner absorbent body (22) has a wall thickness of 0.2 to 3.5 mm.
3. The liquid collecting device according to claim 1, further comprising an upper baffle (12) and a lower baffle (14) arranged at both ends of the sampling rod (13), wherein the upper baffle (12) is fixedly connected with the end of the handle (1).
4. A liquid collecting device according to claim 3, wherein the cross-sectional area of the lower baffle (14) decreases from top to bottom, and the maximum cross-sectional area of the lower baffle (14) is larger than the inner diameter of the receptacle (23) and smaller than the maximum expanded inner diameter of the receptacle (23).
5. A liquid acquisition device according to claim 3, characterized in that the handle (1), the upper baffle (12), the sampling rod (13) and the lower baffle (14) are integrally formed.
6. A liquid acquisition device as claimed in claim 3, wherein the lower baffle is circular in cross-section.
7. A liquid acquisition device according to claim 3, characterized in that a liquid acquisition indicator member (3) is arranged between the absorption body (2) and the upper baffle (12).
CN201811335495.8A 2018-11-10 2018-11-10 Liquid collecting device Active CN111175076B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201811335495.8A CN111175076B (en) 2018-11-10 2018-11-10 Liquid collecting device
PCT/CN2019/076603 WO2020093629A1 (en) 2018-11-10 2019-02-28 Liquid acquisition apparatus

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Application Number Priority Date Filing Date Title
CN201811335495.8A CN111175076B (en) 2018-11-10 2018-11-10 Liquid collecting device

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CN111175076B true CN111175076B (en) 2024-07-23

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CN116019495A (en) * 2023-01-10 2023-04-28 中山大学附属第一医院 Nasal secretion collecting device and method

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