CN111165828A

CN111165828A - Composition and health food for promoting milk secretion

Info

Publication number: CN111165828A
Application number: CN202010211629.6A
Authority: CN
Inventors: 李卫敏
Original assignee: First Affiliated Hospital of Xian Jiaotong University
Current assignee: First Affiliated Hospital of Xian Jiaotong University
Priority date: 2020-03-24
Filing date: 2020-03-24
Publication date: 2020-05-19

Abstract

The invention discloses a composition for promoting milk secretion and health food, and relates to the technical field of health food; the composition includes protein powder, oligopeptide, arginine, probiotics, and stachyose; The composition is prepared into various states of powder, tablet, granule, biscuits, cakes, and liquid milk, so as to be convenient for puerperae to eat. After eating the composition of the present invention, the amount of milk secretion of puerpera increases obviously, which can meet the needs of infants with different food intakes. Moreover, after eating the composition of the present invention, the content of protein, fat and lactose in the milk of the puerperium is also significantly increased, and the symptoms of postpartum constipation of the puerpera can also be relieved at the same time.

Description

Composition and health food for promoting milk secretion

Technical Field

The invention relates to the technical field of health-care food, in particular to a composition for promoting milk secretion and health-care food.

Background

The breast milk is a natural food most suitable for infants, contains amino acids, bifidus factors, unsaturated fatty acids, lactoferrin, DHA, taurine, sphingomyelin, cystine, lecithin and the like required by human bodies, and can promote the development of the mind and intelligence of the infants. The active protein in the breast milk can not only help the infants to improve the immunity, but also reduce the infection of digestive tract, respiratory tract and the like; in addition, breast feeding is also helpful for mother-infant communication, helps the mother recover the weight postpartum, accelerates uterine repair, reduces metabolic syndrome and cardiovascular diseases, and reduces breast cancer, ovarian cancer, postpartum depression and the like. However, many puerperae can not meet the requirement of the baby for breast milk due to insufficient milk secretion or no milk secretion caused by weak body, insufficient qi and blood and other reasons after birth, thereby influencing the physique and intelligence development of the baby.

Disclosure of Invention

In order to solve the problem of insufficient lactation of the puerpera after delivery at present, the invention provides a composition and health food for promoting lactation.

In order to achieve the purpose, one of the technical schemes adopted by the invention is as follows: a composition for promoting milk production, the composition comprising the following raw materials: protein powder, small hundred peptides, arginine, probiotics and stachyose.

Further, the composition comprises the following raw materials: 5-10 parts of protein powder, 46-88 parts of small tripeptide, 5-15 parts of arginine, 5-15 parts of probiotics and 5-10 parts of stachyose.

Still further, the composition comprises the following raw materials: 5 parts of protein powder, 66 parts of small hundred peptides, 10 parts of arginine, 10 parts of probiotics and 6 parts of stachyose.

Furthermore, the protein powder is one or a mixture of whey protein isolate powder, soybean protein isolate powder and pea protein powder.

Still further, the probiotic comprises: lactobacillus acidophilus, Lactobacillus casei, Lactobacillus bulgaricus, Bacillus subtilis, Bifidobacterium longum, Bifidobacterium breve, Bifidobacterium bifidum, Bifidobacterium infantis, Bifidobacterium adolescentis, and Saccharomyces boulardii.

Furthermore, the probiotics are lactobacillus casei, lactobacillus bulgaricus and bifidobacterium infantis, and the mass ratio of the lactobacillus casei, the lactobacillus bulgaricus and the bifidobacterium infantis is 2:1: 2.

The invention also provides application of the composition for promoting milk secretion in any technical scheme in preparation of health-care food.

The invention also provides a health-care product which comprises the composition and acceptable auxiliary materials in health-care food.

Furthermore, the health food can be made into powder, tablet, granule, and liquid milk.

The invention has the beneficial effects that:

firstly, the composition for promoting milk secretion combines protein powder, small hundred peptides, arginine, probiotics and stachyose, takes the small hundred peptide nutrition powder of the broonestle as a base material, the protein powder is added to further increase the protein amount ingested by a puerpera, the added protein powder is the combination of plant protein and animal protein, so that the protein in the milk secreted by the puerpera is better, and then the probiotics and the stachyose are supplemented to repair the damage of the puerpera to the intestinal tract of the puerpera in the pregnancy and the production process, exogenously increase the content of the probiotics in the intestinal tract, and supplement the stachyose to accelerate the proliferation of the probiotics in the body of the puerpera and restore the balance of the intestinal tract microecology of the puerpera, thereby being beneficial to the absorption of nutrient substances by the puerpera, converting the nutrient substances into the milk and increasing the quality and the amount of the milk; arginine is also added into the composition disclosed by the invention, so that the synthesis of protein in a parturient can be further promoted. When the puerpera takes 100g of the health food composition every day after the parturient produces insufficient milk, the lactation yield is increased after the parturient obviously feels that the milk rising time is shortened.

Secondly, the health food composition is convenient to eat and can be taken by being mixed with water every morning and evening.

Thirdly, the health food composition of the invention can also optimize the nutritional structure of the breast milk, so that the breast milk is more nutritious and is beneficial to the development of the body intelligence of the infant.

Finally, as the health food contains probiotics and stachyose, the intestinal microecology of the puerpera can be adjusted, and the problem of postpartum constipation of the puerpera can be effectively solved.

In addition to the objects, features and advantages described above, other objects, features and advantages of the present invention are also provided. The present invention will be described in further detail below with reference to the drawings.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this application, illustrate embodiments of the invention and, together with the description, serve to explain the invention and not to limit the invention.

FIG. 1 is a graph of the change in nutrients in milk before and after consumption of the composition of the invention.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

A composition for promoting milk production according to any embodiment of the invention, the composition comprising the following raw materials: protein powder, small hundred peptides, arginine, probiotics and stachyose.

The components of the composition for promoting milk secretion in the preferred embodiment of the invention can be 5-10 parts of protein powder, 46-88 parts of small hundred peptides, 5-15 parts of arginine, 5-15 parts of probiotics and 5-10 parts of stachyose.

The composition for promoting milk secretion of the optimal embodiment of the invention comprises 5 parts of protein powder, 66 parts of small hundred peptides, 10 parts of arginine, 10 parts of probiotics and 6 parts of stachyose.

Illustratively, the protein may be whey protein, soy protein isolate or pea protein; the whey protein and the soy protein isolate may be mixed, or the whey protein, the pea protein and the soy protein isolate may be mixed.

the whey protein is a powdery product with the protein content of not less than 25 percent, which is prepared by taking whey as a raw material through processes of separation, concentration, drying and the like, contains various essential amino acids, minerals, vitamins and active substances required by a human body, is easy to digest and absorb, has outstanding physiological functional characteristics and high-quality biological utilization value, is one of accepted high-quality protein supplements for the human body, and is also called as 'king of protein'.

Isolated soy protein: the full-value protein food additive is produced by using low-temperature desolventized soybean meal as a raw material, the protein content in the isolated soybean protein is more than 90 percent, the amino acid types are nearly 20, and the isolated soybean protein contains essential amino acids for human bodies. It is rich in nutrients, contains no cholesterol, and is one of a few varieties capable of replacing animal proteins in plant proteins.

The pea protein powder is protein extracted from peas by adopting an advanced process, contains all amino acids necessary for human bodies, and belongs to complete protein. The vegetable protein contains vegetable acid which can affect the absorption of the iron element by human body, but compared with the soybean protein isolate, the phytic acid in the pea protein has less influence on the absorption of the iron element, thereby avoiding the iron deficiency of infants and lying-in women caused by poor absorption; in addition, after the pea protein is decomposed in a human body, the decomposition product has stronger physiological activity and can promote the growth of lactic acid bacteria in intestinal tracts of puerperae.

The L-arginine is a non-essential amino acid, and can meet the metabolic requirements of normal adults by self-synthesis, but the infants are immature because various organs of the body are not developed, and the arginine synthesized in the bodies cannot meet the self-requirements, so that the arginine rich in the health food composition disclosed by the invention enters the bodies of the infants through breast milk, and the weight and the immunity of the infants can be effectively improved; in addition, arginine has various unique physiological and pharmacological effects such as nutrition and immunoregulation, and is a semi-essential amino acid from the nutrition perspective, under the stress conditions of trauma, infection and the like, arginine is beneficial to the synthesis of body proteins, reduces the excretion of urinary nitrogen and improves nitrogen balance, arginine has the effect of regulating the activity of endocrine glands, can promote the secretion of insulin, growth hormone, prolactin, somatostatin, pancreatic polypeptide and the like under the action of pharmacological dosage, and the effect of arginine on regulating protein can be realized by promoting the secretion of insulin and growth hormone.

M-the small hundred peptides are commercially available total nutrient formula powder, preferably Nestle small hundred peptide total nutrient formula powder;

the N-probiotics is a kind of active microorganisms beneficial to a host, and is a general term for active beneficial microorganisms which are planted in the intestinal tract and the reproductive system of a human body and can generate definite health efficacy so as to improve the microbial ecological balance of the host and play beneficial roles. Foreign scholars think that the probiotics can enhance human immunity, promote the health of intestinal digestive system, help to absorb nutrient components and inhibit harmful bacteria from generating toxin;

stachyose is a tetrasaccharide structure formed by α -glucose, β -fructose and 2 alpha-galactoses by alpha-1, 6 glycosidic bonds, has high stability, is easy to dissolve in water, is favorable for processing without influencing the original quality of food, has pure taste and low absorption rate, can be used as a good substitute of sucrose, and like other functional oligosaccharides, the stachyose can not be degraded in the gastrointestinal tract of a human body, but directly reaches the intestinal tract, is utilized by beneficial bacteria in the intestinal tract such as bifidobacterium, lactobacillus and the like, and plays a role in improving the intestinal microecology.

During pregnancy and production, the levels of various hormones in the bodies of lying-in women can change obviously, intestinal flora is disordered, and the constipation of the lying-in women can be caused by the functional decline of abdominal wall muscles and pelvic floor muscles of the lying-in women and the relaxation of the abdominal wall muscles and the pelvic floor muscles of the lying-in women in the production process. According to the invention, the microecology of the intestinal tract is rapidly improved by exogenous probiotic supplementation, and then stachyose is added to further regulate the intestinal tract flora, so that the content of probiotics in the intestinal tract is increased, and the damage to the intestinal tract and a pelvic cavity during pregnancy and production can be rapidly repaired, so that the absorption of the intestinal tract to nutrition can be further promoted, the secretion of milk is increased, and the nutritional ingredients and antigens in the secreted milk are further increased, so that the immunity of the infant is improved.

The composition for promoting milk secretion combines protein powder, small hundred peptides, arginine, probiotics and stachyose, takes the small hundred peptide nutrition powder of a Nestle nest as a base material, the protein powder is added to further increase the protein amount ingested by a puerpera, the added protein powder is the combination of plant protein and animal protein, so that the protein in the milk secreted by the puerpera is better, and then the probiotics and the stachyose are supplemented to repair the damage of the puerpera to the intestinal tract of the puerpera in the pregnancy period and the production process, the content of the probiotics in the intestinal tract is exogenously increased, the stachyose is supplemented, the proliferation of the probiotics in the body of the puerpera is accelerated, the intestinal tract microecology of the puerpera is restored to be balanced, so that the composition is beneficial to the absorption of nutrient substances by the puerpera and is converted into the nutrient substances, and the milk quality and the milk quantity; arginine is also added into the composition disclosed by the invention, so that the synthesis of protein in a parturient can be further promoted.

After taking the composition of any embodiment of the invention for 2 days, the milk secretion of the lying-in woman is obviously increased, the protein content in the milk is increased by 37 percent, and the contents of fat and lactose in the milk are increased.

The protein powder is one or a mixture of two or more of whey protein isolate powder, soybean protein isolate powder, brown rice protein powder and pea protein powder.

Pea protein powder: the vegetable protein contains vegetable acid which can affect the absorption of the iron element by human body, but compared with the soybean protein isolate, the phytic acid in the pea protein has less influence on the absorption of the iron element, thereby avoiding the iron deficiency of infants and lying-in women caused by poor absorption; in addition, after the pea protein is decomposed in a human body, the decomposition product has stronger physiological activity and can promote the growth of lactic acid bacteria in intestinal tracts of puerperae.

The probiotics comprise: lactobacillus acidophilus, Lactobacillus casei, Lactobacillus bulgaricus, Lactobacillus reuteri, Bacillus subtilis, Bifidobacterium longum, Bifidobacterium breve, Bifidobacterium bifidum, Bifidobacterium infantis, Bifidobacterium adolescentis, and Saccharomyces boulardii.

The probiotics comprise lactobacillus casei, lactobacillus bulgaricus and bifidobacterium infantis, and the mass ratio of the lactobacillus casei to the lactobacillus bulgaricus to the bifidobacterium infantis is 2:1: 2.

The health food can be made into powder, tablet, granule, and liquid milk. The powder and the granules can be taken with hot water, when the dinner is eaten, the tablets and the liquid milk can be used as snacks in the gaps of the dinner, and the snack is not required to be secondarily processed before use, so that the dinner is convenient to eat.

The bifidobacterium longum (1000 hundred million cfu/g), the bifidobacterium adolescentis (100 hundred million cfu/g), the bacillus subtilis (200 hundred million cfu/g), the rhamnosus bacillus (100 hundred million cfu/g), the lactobacillus acidophilus (100 hundred million cfu/g), the bifidobacterium infantis (100 hundred million cfu/g), the bacillus brevis (100 hundred million cfu/g), the bifidobacterium bifidum (100 hundred million cfu/g), the lactobacillus bulgaricus (100 hundred million cfu/g), the lactobacillus casei (100 hundred million cfu/g) and the lactobacillus reuteri (100 hundred million cfu/g) are all purchased from Shanxi Junyu Biotech Co., Ltd; saccharomyces boulardii (200 hundred million cfu/g) was purchased from Hui Bo Ankang scientific and technological development, Inc. of Beijing.

Referring to fig. 1, a composition and health food for promoting milk secretion of the present invention includes the following examples:

example 1

A composition for promoting milk production, the composition comprising the following raw materials: 5 parts of whey protein isolate powder, 66 parts of small hundred peptides, 10 parts of arginine, 4 parts of lactobacillus casei, 2 parts of lactobacillus bulgaricus, 4 parts of bifidobacterium infantis and 7 parts of stachyose.

Example 2

A composition for promoting milk production, the composition comprising the following raw materials: 3 parts of pea protein powder, 2 parts of whey protein isolate powder, 88 parts of small hundred peptides, 5 parts of arginine, 5 parts of lactobacillus acidophilus, 10 parts of bifidobacterium longum and 5 parts of stachyose.

Example 3

A composition for promoting milk production, the composition comprising the following raw materials: 4 parts of whey protein isolate powder, 4 parts of pea protein powder, 2 parts of soybean protein isolate, 10 parts of small hundred peptides, 15 parts of arginine, 1 part of lactobacillus reuteri, 2 parts of bifidobacterium adolescentis, 2 parts of bifidobacterium thermophilum and 10 parts of stachyose.

Example 4

A health food comprises the following raw materials: 5 parts of whey protein isolate powder, 66 parts of small hundred peptides, 10 parts of arginine, 4 parts of lactobacillus casei, 2 parts of lactobacillus bulgaricus, 4 parts of bifidobacterium infantis and 7 parts of stachyose.

Weighing the raw materials according to the parts, uniformly mixing, sterilizing, and bagging at 50 g/bag.

Example 5

A health food comprises the following raw materials: 3 parts of pea protein powder, 2 parts of whey protein isolate powder, 88 parts of small hundred peptides, 5 parts of arginine, 5 parts of lactobacillus acidophilus, 10 parts of bifidobacterium longum and 5 parts of stachyose.

The raw materials are prepared into liquid emulsion by a conventional liquid emulsion preparation process.

Example 6

A health food comprises the following raw materials: 4 parts of whey protein isolate powder, 4 parts of pea protein powder, 2 parts of soybean protein isolate, 10 parts of small hundred peptides, 15 parts of arginine, 1 part of lactobacillus reuteri, 2 parts of bifidobacterium adolescentis, 2 parts of bifidobacterium thermophilum and 10 parts of stachyose.

The raw materials are prepared into tablets by a conventional tablet preparation process, and a proper amount of auxiliary materials such as an adhesive, a flavoring agent and the like can be added when necessary, wherein the weight is 5g per tablet.

Experimental example 1

The patient production site: first subsidiary Hospital of the university of Western Ann transportation

Patient 1

The baby is 31 years old, 2016.8.30 is born in good time and 6.4 jin of baby girls, no milk is secreted in 1 day, the baby cries, the composition of the invention is eaten 2 times a day in the next day, 50g of the composition is taken once, the composition is taken with warm boiled water, a small amount of milk is secreted after 1 day, and the milk secretion is obviously increased after 2 days of continuous taking and is enough for the baby to eat.

Patient 2

After the baby is 25 years old and 2015.8.3 is born in the same time, 7 jin of girls and no breast milk exists in 2 days, the baby cry, the composition is eaten 2 times a day in the next day, 50g is carried out once, a small amount of milk is secreted after 1 day, the milk secretion is obviously increased after 2 days, and the milk rising phenomenon appears after one week.

Patient 3

2016.11.5 for the infant male in 2 months at age of 27 years old, the milk secretion of the patient is low, the milk is not enough for the infant in 2 months, milk powder is needed for feeding, the composition of the invention is eaten 1 time a day and 50g once, the milk amount is obviously increased after the composition is eaten for 3 days, the milk rising time is obviously shortened, and the milk amount is increased.

Experimental example 2

Randomly searching 10 puerperae with normal or low milk secretion in a surcharge department, and measuring parameters such as protein, fat, lactose, water, energy, density and the like in the milk secreted by the puerperae with a breast milk analyzer on the 15 th day of production after the puerperae agrees; because the differences and changes of various nutrient components in colostrum are large due to the differences of the physique and the production time of the puerpera, and the content of the nutrient components in the milk is stable about 15 days of production, the date is selected as the date for measuring the content of the nutrient components in the milk of the puerpera, and the results are shown in table 1. After measurement, each parturient consumed 50g of the composition of example 1 of the present invention per day, the eating form was selected by himself, and the powder, granule or tablet was taken directly, and other seasonings were added, the eating habit during the eating process was the same as the eating habit after eating, and the parameters of protein, fat, lactose, minerals, water, energy, density, etc. in the milk secreted from the parturient were measured again after 15 days and 30 days, and the results are shown in table 2,

table 1 analysis of nutritional ingredients in milk before consumption of the composition of the invention

TABLE 2 analysis of nutritional components in milk before consumption of the composition of the invention

As can be seen from tables 1-2 and FIG. 1, the milk had a significant increase in protein content and an increase in lactose and fat content 15 days after consumption of the milk secretion promoting composition of the present invention.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims

1. A composition for promoting milk secretion, characterized in that the composition comprises the following components: protein powder, oligopeptide, arginine, probiotics, and stachyose.

2. The composition for promoting milk secretion according to claim 1, wherein the composition comprises the following components: 5-10 parts of protein powder, 46-88 parts of oligopeptide, 5-15 parts of arginine , 5-15 parts of probiotics, 5-10 parts of stachyose.

3. The composition for promoting milk secretion according to claim 1, wherein the composition comprises the following components: 5 parts of protein powder, 66 parts of oligopeptide, 10 parts of arginine, 10 parts of probiotics, 6 servings of stachyose.

4. The composition for promoting milk secretion according to any one of claims 1-3, wherein the protein powder is one or more of whey protein isolate powder, soybean protein isolate powder, pea protein powder mix.

5. The composition for promoting milk secretion according to any one of claims 1-3, wherein the probiotics comprise: Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus bulgaricus, Bacillus subtilis, Bifidobacterium longum , Bifidobacterium breve, Bifidobacterium bifidum, Bifidobacterium infantis, Bifidobacterium adolescentis, Saccharomyces boulardii, or a mixture of the same species.

6. according to the arbitrary described composition of claim 1-3 that promotes milk secretion, it is characterized in that, described probiotic is Lactobacillus casei, Lactobacillus bulgaricus and Bifidobacterium infantis, Lactobacillus casei, Lactobacillus bulgaricus and infant The mass ratio of bifidobacteria was 2:1:4.

7. The application of the composition for promoting milk secretion according to any one of claims 1-6 in the preparation of health food.

8. A health-care food, characterized in that the health-care food comprises any of the compositions of claims 1-3 and acceptable auxiliary materials in the health-care food.

9 . The health product according to claim 8 , wherein the dosage form of the health food is powder, tablet, granule, and liquid milk. 10 .