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CN111084928A - Prostate treatment device based on temperature partition - Google Patents

Prostate treatment device based on temperature partition Download PDF

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Publication number
CN111084928A
CN111084928A CN201911282243.8A CN201911282243A CN111084928A CN 111084928 A CN111084928 A CN 111084928A CN 201911282243 A CN201911282243 A CN 201911282243A CN 111084928 A CN111084928 A CN 111084928A
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parts
heating
uniformly mixing
layer
treatment device
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刘敏
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/30Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/38Silver; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
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    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
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    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
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    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • AHUMAN NECESSITIES
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    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3368Temperature
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/36General characteristics of the apparatus related to heating or cooling
    • A61M2205/3653General characteristics of the apparatus related to heating or cooling by Joule effect, i.e. electric resistance

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Abstract

The application discloses prostate treatment device based on temperature partition, be equipped with the installation cavity in the box, the lithium cell is installed to the upper end of box, be equipped with a plurality of filling tubes on the box, be equipped with the feeding chamber in the filling tube, be equipped with a plurality of charging tubes in the box, the charging chamber that is equipped with and feeds through with the feeding chamber in the charging tube, it has the traditional chinese medicine filling layer to fill intracavity, the net bars is installed to the charging intracavity, the bottom-mounting has ventilative layer in the charging tube, still install net bars in the charging tube, it has the zone of heating to fill between net bars and the ventilative layer, the one end of lithium cell is equipped with the insulating conductor wire that runs through the box, insulating conductor wire runs through net bars and has many heating resistor silk in the zone of heating, one side that the charging tube is close to the box is equipped with ventilative layer, the interior bottom of box. The prostate treatment device can heat in a subarea manner, and has good sterilization effect and good treatment effect.

Description

Prostate treatment device based on temperature partition
Technical Field
The invention relates to the technical field of medical equipment, in particular to a prostate treatment device based on temperature partition.
Background
The existing device for treating the prostatic hyperplasia generally uses an infrared heat radiation, laser and ultrasonic generation device, and treats the affected part of the prostate through the rectum, the therapeutic apparatus can not effectively relieve the symptoms of the prostatic hyperplasia and has certain side effects, the device for treating by using traditional Chinese medicines is generally a traditional Chinese medicine patch, and the traditional Chinese medicine patch has certain treatment effect, but has slow effect and poor treatment effect, and can not meet the requirement of actual treatment.
Through the retrieval, chinese patent application No. 201510166800.5's patent discloses a prostate treatment device, comprises a box bod, the sleeve, the mainboard, the collection liquid bottle, heater and anion generator, the box body includes bottom plate and apron, apron detachably lid closes on the bottom plate, the mainboard, the collection liquid bottle, heater and anion generator set up in the box body, collection liquid bottle detachably fixes on the apron, the heater sets up in the collection liquid bottle, be provided with the water pump in the collection liquid bottle, anion generator fixes on the apron, anion generator leads to the pipe to be connected with collection liquid bottle, the mainboard is fixed on the bottom plate, the mainboard respectively with the heater, the water pump, anion generator electricity is connected, the sleeve sets up outside the box body, sleeve one end passes through inlet tube and collection liquid bottle intercommunication, the sleeve other end passes through outlet pipe and anion generator intercommunication, sleeve one end has the opening. The prostate treatment device has simple structure, convenient use and carrying, can increase endurance capacity, and has definite effect of treating erectile dysfunction, and remarkable and rapid curative effect. The prostate treatment device in the above patent has the following disadvantages: has poor antibacterial effect and poor therapeutic effect.
Disclosure of Invention
The technical problem to be solved by the present invention is to overcome the shortcomings of the prior art and to provide a prostate treatment device based on temperature partitioning.
The technical scheme adopted by the invention is as follows:
a prostate treatment device based on temperature zoning comprises a box body, wherein a mounting cavity is arranged in the box body, a lithium battery is mounted at the upper end of the box body, a handle is mounted on the lithium battery, an anti-skidding sleeve is arranged on the handle, a plurality of feeding pipes are arranged on the box body, a feeding cavity is arranged in each feeding pipe, a plurality of charging pipes are arranged in the box body, a charging cavity communicated with the feeding cavity is arranged in each charging pipe, a traditional Chinese medicine filling layer is filled in each charging cavity, a grid is mounted in each charging cavity, a breathable layer is mounted at the bottom in each charging pipe, a grid is further mounted in each charging pipe, a heating layer is filled between each grid and each breathable layer, one end of each lithium battery is provided with an insulated conducting wire penetrating through the box body, a plurality of heating resistance wires are connected in each heating layer through each grid, each charging pipe is provided with, breathable gauze is arranged between the grid and the Chinese medicinal filling layer.
Preferably, the traditional Chinese medicine filling layer comprises the following raw materials in parts by weight: 20-30 parts of cortex moutan, 15-25 parts of moxa oil, 4-8 parts of houttuynia cordata, 3-9 parts of polyethyleneimine, 4-8 parts of bitter gourd juice, 4-7 parts of polylactic acid, 1-6 parts of bamboo charcoal fiber, 8-16 parts of antibacterial penetrant, 12-24 parts of slow release auxiliary agent, 8-16 parts of melamine resin and 4-8 parts of 1, 3-butanediol.
Preferably, the bacteriostatic penetrating agent comprises the following raw materials in parts by weight: 10-20 parts of urea, 4-8 parts of polyvinylpyrrolidone, 15-35 parts of deionized water, 4-8 parts of sodium chloride, 4-8 parts of emulsified silicone oil, 3-6 parts of zinc oxide, 4-8 parts of natural zeolite, 2-6 parts of a sodium chloride solution with the mass fraction of 5-15%, 2-6 parts of a lanthanum chloride solution with the mass fraction of 4-8%, 5-8 parts of a silver nitrate solution with the mass fraction of 3-9% and 3-9 parts of disodium hydrogen phosphate.
Preferably, the bacteriostatic penetrating agent is prepared by the following process: uniformly mixing urea, polyvinylpyrrolidone and deionized water, adding sodium chloride and emulsified silicone oil, stirring for 10-30min, and adding zinc oxide to obtain a material a; uniformly mixing natural zeolite and a sodium chloride solution with the mass fraction of 5-15%, stirring for 1-3h, filtering, dehydrating and drying, then roasting at 550 ℃ of 450-; and then uniformly mixing the material a and the material b, heating to 70-90 ℃ in a water bath, cooling to room temperature, adding disodium hydrogen phosphate, uniformly mixing, aging, filtering, washing, drying, calcining, and cooling to room temperature to obtain the antibacterial penetrant.
Preferably, the raw materials of the slow release auxiliary agent comprise, by weight: 5-15 parts of sodium hydroxide, 4-8 parts of polyethylene glycol, 20-40 parts of water, 4-8 parts of rice bran wax, 3-6 parts of sepiolite powder, 2-6 parts of calcium chloride, 1-5 parts of ethyl alcohol, 4-8 parts of sodium dodecyl benzene sulfonate and 6-4 parts of silane coupling agent KH-5703.
Preferably, the sustained-release auxiliary agent is prepared by the following process: uniformly mixing sodium hydroxide, polyethylene glycol and water, heating to 65-75 ℃, adding rice bran wax and sepiolite powder, uniformly mixing, stirring for 15-35min, heating to 75-85 ℃, preserving heat for 1-3h, adding calcium chloride, uniformly mixing, heating to 85-95 ℃, preserving heat for 20-40min, cooling to room temperature, washing, carrying out suction filtration, evaporation, drying, cooling and solidifying to obtain a material A; uniformly mixing the material A and ethyl alcohol, stirring for 20-40min at the rotation speed of 850-.
Preferably, the traditional Chinese medicine filling layer is prepared by the following process:
s1: uniformly mixing cortex moutan, blumea oil, houttuynia cordata, polyethyleneimine, bitter gourd juice, polylactic acid and bamboo charcoal fiber, heating to 80-90 ℃, preserving heat for 20-30min, stirring at the rotation speed of 650 plus 850r/min for 20-40min, and cooling to room temperature to obtain a material I;
s2: uniformly mixing the material I, the bacteriostatic penetrating agent, the melamine resin and the 1, 3-butanediol, heating to 110-;
s3: and (5) putting the material II prepared in the step (S2) into a forming machine to be made into a circular block with the diameter of 60mm and the height of 15mm, and drying to obtain the traditional Chinese medicine filling layer.
The invention has the beneficial effects that:
supply power to heating resistance wire through insulating conductor wire through the lithium cell, generate heat by heating resistance wire and realize heating the zone of heating, then realize heating traditional chinese medicine filling layer by the zone of heating, the steam that traditional chinese medicine filling layer produced after being heated sees through ventilative gauze and grid, then permeate in skin through ventilative layer and sponge layer, absorb after permeating through skin, set up through making the quantity difference of the heating resistance wire in each charging tube, so realized the heating of temperature subregion, carry out the heating of different temperatures to the position that does not the prostate difference, and the traditional chinese medicine filling layer of charging chamber adds the material by the filling tube, so realized carrying out subregion temperature heating to the prostate, the effect of prostate treatment has so improved.
Wherein, the bacteriostatic penetrating agent in the traditional Chinese medicine filling layer is prepared by uniformly mixing urea, polyvinylpyrrolidone and deionized water, then adding sodium chloride and emulsified silicone oil, stirring, and then adding zinc oxide to obtain a material a; mixing natural zeolite and sodium chloride solution, stirring, filtering, dewatering, oven drying, roasting, adding into lanthanum chloride solution, stirring, filtering, dewatering, oven drying, roasting, adding into silver nitrate solution, stirring, and oven drying to obtain the final productTo the material b; then uniformly mixing the material a and the material b, heating in water bath, cooling to room temperature, adding disodium hydrogen phosphate, uniformly mixing, aging, filtering, washing, drying, calcining and cooling to room temperature to obtain the compound zeolite, wherein polyvinylpyrrolidone is used as a film forming substance, urea has a moisturizing effect, emulsified silicone oil is used as a defoaming agent, zinc element in zinc oxide has an antibacterial effect, a large amount of round beads exist on the surface of modified zeolite which takes natural zeolite as a raw material, and the surface pore diameter of the compound zeolite is reduced compared with that of the modified zeolite, probably because AgNO adsorbed on the surface of zeolite particles3Not completely eluted, and decomposed to form Ag in the drying process2O is agglomerated on the surface of the antibacterial adsorption material to cause partial small holes of the zeolite to be blocked, so that a certain amount of silver exists in cation exchange positions and pore passages of the antibacterial adsorption material in an ion form in the silver type antibacterial zeolite, and partial Ag exists in the silver type antibacterial zeolite2O exists on the surface of the material, so that the sufficient contact area of silver ions and the escherichia coli is ensured. In the modification and combination process, most of sodium ions and silver ions enter the zeolite through ion exchange, and the nitrogen removal of the composite zeolite is carried out by using sodium ions and other cations in the zeolite structure and NH4+Ion exchange occurs, phosphorus removal depends on electrostatic adsorption of hydrated lanthanum oxide on the surface of zeolite, and the antibacterial property is realized because antibacterial Ag ions with sterilizing property are loaded and applied to the preparation of the traditional Chinese medicine filling layer, so that the traditional Chinese medicine filling layer has excellent antibacterial property.
Wherein, the slow release auxiliary agent is prepared by mixing sodium hydroxide, polyethylene glycol and water, heating, adding rice bran wax and sepiolite powder, heating, adding calcium chloride, heating, cooling to room temperature, washing, filtering, evaporating, drying, cooling, solidifying, mixing with ethyl alcohol, adding sodium dodecyl benzene sulfonate and silane coupling agent KH-570, mixing, stirring, placing into a bulking machine, bulking, crushing, sieving, collecting fine powder, cooling to room temperature, utilizing the porosity of the sepiolite powder, utilizing the graft modification effect of the silane coupling agent KH-570 to realize the combination of the hydroxyl groups on the surfaces of the rice bran wax and the calcium chloride and the sepiolite, preparing the slow release auxiliary agent with viscosity and porosity under the action of the ethyl alcohol and the sodium dodecyl benzene sulfonate, applying to the preparation of the traditional Chinese medicine filling layer, the antibacterial filling layer is matched with the antibacterial penetrant, so that abundant attachment sites are provided for the antibacterial penetrant, the forming of the traditional Chinese medicine filling layer is promoted, a certain shape can be still kept in the heating process, the antibacterial time is effectively prolonged, and the antibacterial efficiency and quality are improved.
Drawings
Fig. 1 is a schematic structural diagram of a prostate treatment device based on temperature zones according to an embodiment of the present invention;
figure 2 is a bottom view of a temperature-partition based prostate treatment device according to an embodiment of the present invention;
fig. 3 is a sectional view showing the fitting of the tank and the filling tube in the prostate treatment device based on temperature zoning according to the embodiment of the present invention;
fig. 4 is a partially enlarged schematic view at a in fig. 3.
The figures are numbered:
1. a box body; 2. a feed tube; 3. a lithium battery; 4. a handle; 5. an anti-slip sleeve; 6. a sponge layer; 7. a charging pipe; 8. an insulated conductive wire; 9. breathable gauze; 10. a grid; 11. a heating layer; 12. heating resistance wires; 13. a breathable layer; 14. a traditional Chinese medicine filling layer; 15. a charging chamber; 16. a feed chamber.
Detailed Description
The technical solutions of the embodiments of the present invention are explained and illustrated below with reference to the drawings of the embodiments of the present invention, but the following embodiments are only preferred embodiments of the present invention, and not all embodiments. Based on the embodiments in the implementation, other embodiments obtained by those skilled in the art without any creative effort belong to the protection scope of the present invention.
In the following description, the appearances of the indicating orientation or positional relationship such as the terms "inner", "outer", "upper", "lower", "left", "right", etc. are only for convenience in describing the embodiments and for simplicity in description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and are not to be construed as limiting the present invention.
Example 1:
as shown in fig. 1-4, the prostate treatment device based on temperature zoning comprises a box body 1, a mounting cavity 6 is arranged in the box body 1, a lithium battery 3 is mounted at the upper end of the box body 1, a handle 4 is mounted on the lithium battery 3, an anti-slip sleeve 5 is arranged on the handle 4, a plurality of feeding pipes 2 are arranged on the box body 1, a feeding cavity 16 is arranged in each feeding pipe 2, a plurality of charging pipes 7 are arranged in the box body 1, a charging cavity 15 communicated with the feeding cavity 16 is arranged in each charging pipe 7, a traditional Chinese medicine filling layer 14 is filled in each charging cavity 15, a grid 10 is mounted in each charging cavity 15, a breathable layer 13 is mounted at the bottom in each charging pipe 7, a grid 10 is further mounted in each charging pipe 7, a heating layer 11 is filled between each grid 10 and the breathable layer 13, an insulated conductive wire 8 penetrating through the box body 1 is arranged at one end of each lithium battery 3, the insulated conductive, one side that charging tube 7 is close to box 1 is equipped with ventilative layer 13, and the interior bottom of box 1 is equipped with a plurality of sponge layers 6, and sponge layer 6 arranges with ventilative layer 13 contact, is equipped with ventilative gauze 9 between net bars 10 and the traditional chinese medicine filling layer 14.
In this embodiment, the traditional Chinese medicine filling layer 14 comprises the following raw materials in parts by weight: 25 parts of cortex moutan, 20 parts of argy wormwood oil, 6 parts of houttuynia cordata, 6 parts of polyethyleneimine, 6 parts of bitter gourd juice, 5.5 parts of polylactic acid, 3.5 parts of bamboo charcoal fiber, 12 parts of bacteriostatic penetrating agent, 18 parts of slow release auxiliary agent, 12 parts of melamine resin and 6 parts of 1, 3-butanediol.
In this embodiment, the bacteriostatic penetrant is prepared according to the following process: uniformly mixing 15 parts of urea, 6 parts of polyvinylpyrrolidone and 25 parts of deionized water according to parts by weight, adding 6 parts of sodium chloride and 6 parts of emulsified silicone oil, stirring for 20min, and adding 4.5 parts of zinc oxide to obtain a material a; uniformly mixing 6 parts of natural zeolite and 4 parts of a sodium chloride solution with the mass fraction of 10%, stirring for 2 hours, filtering, dehydrating, drying, roasting at 500 ℃ for 1 hour, then placing in 4 parts of a lanthanum chloride solution with the mass fraction of 6%, stirring for 2 hours, filtering, dehydrating, drying, then placing in 200 ℃ for roasting for 1 hour, then placing in 6.5 parts of a silver nitrate solution with the mass fraction of 6%, stirring for 3 hours, and drying to obtain a material b; and then uniformly mixing the material a and the material b, heating to 80 ℃ in a water bath, cooling to room temperature, adding 6 parts of disodium hydrogen phosphate, uniformly mixing, aging, filtering, washing, drying, calcining, and cooling to room temperature to obtain the antibacterial penetrant.
In this example, the sustained release adjuvant is prepared as follows: uniformly mixing 10 parts of sodium hydroxide, 6 parts of polyethylene glycol and 30 parts of water according to parts by weight, heating to 70 ℃, adding 6 parts of rice bran wax and 4.5 parts of sepiolite powder, uniformly mixing, stirring for 25min, heating to 80 ℃, preserving heat for 2h, adding 4 parts of calcium chloride, uniformly mixing, heating to 90 ℃, preserving heat for 30min, cooling to room temperature, washing, filtering, evaporating, drying, cooling and solidifying to obtain a material A; uniformly mixing the material A and 3 parts of ethyl alcohol, stirring for 30min at the rotating speed of 900r/min, then adding 6 parts of sodium dodecyl benzene sulfonate and 4.5 parts of silane coupling agent KH-570, uniformly mixing, stirring for 25min at the rotating speed of 550r/min, then putting into a bulking machine, bulking, crushing and sieving at 220 ℃ and 0.65MPa, collecting 300-mesh fine powder, and cooling to room temperature to obtain the slow-release auxiliary agent.
In this embodiment, the traditional Chinese medicine filling layer 14 is prepared according to the following processes:
s1: uniformly mixing cortex moutan, folium artemisiae argyi oil, houttuynia cordata, polyethyleneimine, balsam pear juice, polylactic acid and bamboo charcoal fibers, heating to 85 ℃, preserving heat for 25min, stirring at the rotating speed of 750r/min for 30min, and cooling to room temperature to obtain a material I;
s2: uniformly mixing the material I, the bacteriostatic penetrating agent, the melamine resin and the 1, 3-butanediol, heating to 115 ℃, preserving heat for 20min, then cooling to 55 ℃, adding the slow release auxiliary agent, uniformly mixing, stirring at the rotating speed of 2000r/min for 30min, and cooling to room temperature to obtain a material II;
s3: and (5) putting the material II prepared in the step (S2) into a forming machine to be made into a circular block with the diameter of 60mm and the height of 15mm, and drying to obtain the traditional Chinese medicine filling layer 14.
Example 2
As shown in fig. 1-4, the prostate treatment device based on temperature zoning comprises a box body 1, a mounting cavity 6 is arranged in the box body 1, a lithium battery 3 is mounted at the upper end of the box body 1, a handle 4 is mounted on the lithium battery 3, an anti-slip sleeve 5 is arranged on the handle 4, a plurality of feeding pipes 2 are arranged on the box body 1, a feeding cavity 16 is arranged in each feeding pipe 2, a plurality of charging pipes 7 are arranged in the box body 1, a charging cavity 15 communicated with the feeding cavity 16 is arranged in each charging pipe 7, a traditional Chinese medicine filling layer 14 is filled in each charging cavity 15, a grid 10 is mounted in each charging cavity 15, a breathable layer 13 is mounted at the bottom in each charging pipe 7, a grid 10 is further mounted in each charging pipe 7, a heating layer 11 is filled between each grid 10 and the breathable layer 13, an insulated conductive wire 8 penetrating through the box body 1 is arranged at one end of each lithium battery 3, the insulated conductive, one side that charging tube 7 is close to box 1 is equipped with ventilative layer 13, and the interior bottom of box 1 is equipped with a plurality of sponge layers 6, and sponge layer 6 arranges with ventilative layer 13 contact, is equipped with ventilative gauze 9 between net bars 10 and the traditional chinese medicine filling layer 14.
In this embodiment, the traditional Chinese medicine filling layer 14 comprises the following raw materials in parts by weight: 20 parts of cortex moutan, 25 parts of argy wormwood leaf oil, 4 parts of houttuynia cordata, 9 parts of polyethyleneimine, 4 parts of balsam pear juice, 7 parts of polylactic acid, 1 part of bamboo charcoal fiber, 16 parts of bacteriostatic penetrating agent, 12 parts of slow release auxiliary agent, 16 parts of melamine resin and 4 parts of 1, 3-butanediol.
In this embodiment, the bacteriostatic penetrant is prepared according to the following process: uniformly mixing 10 parts of urea, 8 parts of polyvinylpyrrolidone and 15 parts of deionized water according to parts by weight, adding 8 parts of sodium chloride and 4 parts of emulsified silicone oil, stirring for 30min, and adding 3 parts of zinc oxide to obtain a material a; uniformly mixing 8 parts of natural zeolite and 2 parts of sodium chloride solution with the mass fraction of 15%, stirring for 1h, filtering, dehydrating, drying, roasting at 550 ℃ for 0.5h, then placing in 6 parts of lanthanum chloride solution with the mass fraction of 4%, stirring for 3h, filtering, dehydrating, drying, then placing in 180 ℃ for 1.5h, then placing in 5 parts of silver nitrate solution with the mass fraction of 9%, stirring for 2h, and drying to obtain a material b; and then uniformly mixing the material a and the material b, heating to 90 ℃ in a water bath, cooling to room temperature, adding 3 parts of disodium hydrogen phosphate, uniformly mixing, aging, filtering, washing, drying, calcining, and cooling to room temperature to obtain the antibacterial penetrant.
In this example, the sustained release adjuvant is prepared as follows: uniformly mixing 5 parts of sodium hydroxide, 8 parts of polyethylene glycol and 20 parts of water according to parts by weight, heating to 75 ℃, adding 4 parts of rice bran wax and 6 parts of sepiolite powder, uniformly mixing, stirring for 15min, heating to 85 ℃, preserving heat for 1h, adding 6 parts of calcium chloride, uniformly mixing, heating to 85 ℃, preserving heat for 40min, cooling to room temperature, washing, carrying out suction filtration, evaporation, drying, cooling and solidifying to obtain a material A; uniformly mixing the material A with 1 part of ethyl alcohol, stirring at the rotation speed of 950r/min for 20min, then adding 8 parts of sodium dodecyl benzene sulfonate and 3 parts of silane coupling agent KH-570, uniformly mixing, stirring at the rotation speed of 650r/min for 20min, then placing into a bulking machine, bulking at 240 ℃ and 0.6MPa, crushing, sieving, collecting 350-mesh fine powder, and cooling to room temperature to obtain the slow-release assistant.
In this embodiment, the traditional Chinese medicine filling layer 14 is prepared according to the following processes:
s1: uniformly mixing cortex moutan, folium artemisiae argyi oil, houttuynia cordata, polyethyleneimine, balsam pear juice, polylactic acid and bamboo charcoal fibers, heating to 80 ℃, preserving heat for 30min, stirring at the rotating speed of 650r/min for 40min, and cooling to room temperature to obtain a material I;
s2: uniformly mixing the material I, the bacteriostatic penetrating agent, the melamine resin and the 1, 3-butanediol, heating to 110 ℃, preserving heat for 25min, then cooling to 50 ℃, adding the slow release auxiliary agent, uniformly mixing, stirring at the rotating speed of 2500r/min for 20min, and cooling to room temperature to obtain a material II;
s3: and (5) putting the material II prepared in the step (S2) into a forming machine to be made into a circular block with the diameter of 60mm and the height of 15mm, and drying to obtain the traditional Chinese medicine filling layer 14.
Example 3
As shown in fig. 1-4, the prostate treatment device based on temperature zoning comprises a box body 1, a mounting cavity 6 is arranged in the box body 1, a lithium battery 3 is mounted at the upper end of the box body 1, a handle 4 is mounted on the lithium battery 3, an anti-slip sleeve 5 is arranged on the handle 4, a plurality of feeding pipes 2 are arranged on the box body 1, a feeding cavity 16 is arranged in each feeding pipe 2, a plurality of charging pipes 7 are arranged in the box body 1, a charging cavity 15 communicated with the feeding cavity 16 is arranged in each charging pipe 7, a traditional Chinese medicine filling layer 14 is filled in each charging cavity 15, a grid 10 is mounted in each charging cavity 15, a breathable layer 13 is mounted at the bottom in each charging pipe 7, a grid 10 is further mounted in each charging pipe 7, a heating layer 11 is filled between each grid 10 and the breathable layer 13, an insulated conductive wire 8 penetrating through the box body 1 is arranged at one end of each lithium battery 3, the insulated conductive, one side that charging tube 7 is close to box 1 is equipped with ventilative layer 13, and the interior bottom of box 1 is equipped with a plurality of sponge layers 6, and sponge layer 6 arranges with ventilative layer 13 contact, is equipped with ventilative gauze 9 between net bars 10 and the traditional chinese medicine filling layer 14.
In this embodiment, the traditional Chinese medicine filling layer 14 comprises the following raw materials in parts by weight: 30 parts of cortex moutan, 15 parts of argy wormwood leaf oil, 8 parts of houttuynia cordata, 3 parts of polyethyleneimine, 8 parts of bitter gourd juice, 4 parts of polylactic acid, 6 parts of bamboo charcoal fiber, 8 parts of bacteriostatic penetrating agent, 24 parts of slow release auxiliary agent, 8 parts of melamine resin and 8 parts of 1, 3-butanediol.
In this embodiment, the bacteriostatic penetrant is prepared according to the following process: uniformly mixing 20 parts of urea, 4 parts of polyvinylpyrrolidone and 35 parts of deionized water according to parts by weight, adding 4 parts of sodium chloride and 8 parts of emulsified silicone oil, stirring for 10min, and adding 6 parts of zinc oxide to obtain a material a; uniformly mixing 4 parts of natural zeolite and 6 parts of sodium chloride solution with the mass fraction of 5%, stirring for 3 hours, filtering, dehydrating and drying, then roasting at 450 ℃ for 1.5 hours, then placing in 2 parts of lanthanum chloride solution with the mass fraction of 8%, stirring for 1 hour, filtering, dehydrating and drying, then placing in 220 ℃ for 0.5 hour, then placing in 8 parts of silver nitrate solution with the mass fraction of 3%, stirring for 4 hours, and drying to obtain a material b; and then uniformly mixing the material a and the material b, heating to 70 ℃ in a water bath, cooling to room temperature, adding 9 parts of disodium hydrogen phosphate, uniformly mixing, aging, filtering, washing, drying, calcining, and cooling to room temperature to obtain the antibacterial penetrant.
In this example, the sustained release adjuvant is prepared as follows: uniformly mixing 15 parts of sodium hydroxide, 4 parts of polyethylene glycol and 40 parts of water according to parts by weight, heating to 65 ℃, adding 8 parts of rice bran wax and 3 parts of sepiolite powder, uniformly mixing, stirring for 35min, heating to 75 ℃, preserving heat for 3h, adding 2 parts of calcium chloride, uniformly mixing, heating to 95 ℃, preserving heat for 20min, cooling to room temperature, washing, carrying out suction filtration, evaporation, drying, cooling and solidifying to obtain a material A; uniformly mixing the material A with 5 parts of ethyl alcohol, stirring at the rotating speed of 850r/min for 40min, then adding 4 parts of sodium dodecyl benzene sulfonate and 6 parts of silane coupling agent KH-570, uniformly mixing, stirring at the rotating speed of 450r/min for 30min, then placing into a bulking machine, bulking at 200 ℃ and 0.7MPa, crushing, sieving, collecting 250-mesh fine powder, and cooling to room temperature to obtain the slow-release auxiliary agent.
In this embodiment, the traditional Chinese medicine filling layer 14 is prepared according to the following processes:
s1: uniformly mixing cortex moutan, blumea oil, houttuynia cordata, polyethyleneimine, bitter gourd juice, polylactic acid and bamboo charcoal fiber, heating to 80-90 ℃, preserving heat for 20-30min, stirring at the rotation speed of 650 plus 850r/min for 20-40min, and cooling to room temperature to obtain a material I;
s2: uniformly mixing the material I, the bacteriostatic penetrating agent, the melamine resin and the 1, 3-butanediol, heating to 120 ℃, preserving heat for 15min, then cooling to 60 ℃, adding the slow release auxiliary agent, uniformly mixing, stirring at the rotating speed of 1500r/min for 40min, and cooling to room temperature to obtain a material II;
s3: and (5) putting the material II prepared in the step (S2) into a forming machine to be made into a circular block with the diameter of 60mm and the height of 15mm, and drying to obtain the traditional Chinese medicine filling layer 14.
Comparative example 1
A prostate treatment device (application No. 201510166800.5) "according to the Chinese patent application is used.
The indexes of the examples 1 to 3 and the comparative example 1 are tested, and the test results are shown in the following table:
experimental groups Value of bacteriostatic activity Absorption rate (%)
Example 1 5.6 99.8
Example 2 5.3 98.9
Example 3 5.4 98.4
Comparative example 1 1.5 16.8
Through the data analysis, the heating resistance wire is powered through the lithium battery through the insulated electric lead, the heating layer is heated through the heating resistance wire, then the traditional Chinese medicine filling layer is heated through the heating layer, steam generated after the traditional Chinese medicine filling layer is heated penetrates through the breathable gauze and the grid, then penetrates into the skin through the breathable layer and the sponge layer, and is absorbed through the skin after penetration, the heating resistance wires in the charging pipes are arranged in different numbers, so that the temperature zone heating is realized, the heating at different temperatures is carried out on different positions of the prostate, the materials are added into the traditional Chinese medicine filling layer in the charging cavity through the charging pipe, so that the zone temperature heating treatment on the prostate is realized, and the prostate treatment effect is improved.
Wherein, the bacteriostatic penetrating agent in the traditional Chinese medicine filling layer is prepared by uniformly mixing urea, polyvinylpyrrolidone and deionized water, then adding sodium chloride and emulsified silicone oil, stirring, and then adding zinc oxide to obtain a material a; mixing natural zeolite and a sodium chloride solution uniformly, stirring, filtering, dehydrating, drying, roasting, placing in a lanthanum chloride solution, stirring, filtering, dehydrating, drying, roasting, placing in a silver nitrate solution, stirring, and drying to obtain a material b; then the material a is mixedMixing with material b, heating in water bath, cooling to room temperature, adding disodium hydrogen phosphate, aging, filtering, washing, drying, calcining, and cooling to room temperature to obtain the final product, wherein polyvinylpyrrolidone is used as film forming substance, urea has moisture keeping effect, emulsified silicone oil is used as defoaming agent, zinc element in zinc oxide has antibacterial effect, natural zeolite is used as raw material, and modified zeolite has a large amount of beads on its surface, and the surface pore size of composite zeolite is smaller than that of modified zeolite, probably due to AgNO adsorbed on the surface of zeolite particles3Not completely eluted, and decomposed to form Ag in the drying process2O is agglomerated on the surface of the antibacterial adsorption material to cause partial small holes of the zeolite to be blocked, so that a certain amount of silver exists in cation exchange positions and pore passages of the antibacterial adsorption material in an ion form in the silver type antibacterial zeolite, and partial Ag exists in the silver type antibacterial zeolite2O exists on the surface of the material, so that the sufficient contact area of silver ions and the escherichia coli is ensured. In the modification and combination process, most of sodium ions and silver ions enter the zeolite through ion exchange, and the nitrogen removal of the composite zeolite is carried out by using sodium ions and other cations in the zeolite structure and NH4+Ion exchange occurs, phosphorus removal depends on electrostatic adsorption of hydrated lanthanum oxide on the surface of zeolite, and the antibacterial property is realized because antibacterial Ag ions with sterilizing property are loaded and applied to the preparation of the traditional Chinese medicine filling layer, so that the traditional Chinese medicine filling layer has excellent antibacterial property.
Wherein, the slow release auxiliary agent is prepared by mixing sodium hydroxide, polyethylene glycol and water, heating, adding rice bran wax and sepiolite powder, heating, adding calcium chloride, heating, cooling to room temperature, washing, filtering, evaporating, drying, cooling, solidifying, mixing with ethyl alcohol, adding sodium dodecyl benzene sulfonate and silane coupling agent KH-570, mixing, stirring, placing into a bulking machine, bulking, crushing, sieving, collecting fine powder, cooling to room temperature, utilizing the porosity of the sepiolite powder, utilizing the graft modification effect of the silane coupling agent KH-570 to realize the combination of the hydroxyl groups on the surfaces of the rice bran wax and the calcium chloride and the sepiolite, preparing the slow release auxiliary agent with viscosity and porosity under the action of the ethyl alcohol and the sodium dodecyl benzene sulfonate, applying to the preparation of the traditional Chinese medicine filling layer, the antibacterial filling layer is matched with the antibacterial penetrant, so that abundant attachment sites are provided for the antibacterial penetrant, the forming of the traditional Chinese medicine filling layer is promoted, a certain shape can be still kept in the heating process, the antibacterial time is effectively prolonged, and the antibacterial efficiency and quality are improved.
The above description is only for the preferred embodiment of the present invention and is not intended to limit the scope of the present invention, and all equivalent structural changes made by using the contents of the present specification and the drawings can be directly or indirectly applied to other related technical fields and are included in the scope of the present invention.

Claims (7)

1. A prostate treatment device based on temperature zoning is characterized by comprising a box body, wherein a mounting cavity is arranged in the box body, a lithium battery is mounted at the upper end of the box body, a handle is mounted on the lithium battery, an anti-skidding sleeve is arranged on the handle, a plurality of feeding pipes are arranged on the box body, a feeding cavity is arranged in each feeding pipe, a plurality of feeding pipes are arranged in each feeding pipe, a feeding cavity communicated with the feeding cavity is arranged in each feeding pipe, a traditional Chinese medicine filling layer is filled in each feeding cavity, a grid is mounted in each feeding cavity, a breathable layer is mounted at the bottom in each feeding pipe, a grid is further mounted in each feeding pipe, a heating layer is filled between each grid and the breathable layer, an insulated conducting wire penetrating through the box body is arranged at one end of each lithium battery, a plurality of heating resistance wires are connected in each heating layer by penetrating, the sponge layer is arranged in contact with the air permeable layer, and air permeable gauze is arranged between the grid and the Chinese medicinal filling layer.
2. The prostate treatment device based on temperature zones of claim 1, wherein the traditional Chinese medicine filling layer comprises the following raw materials in parts by weight: 20-30 parts of cortex moutan, 15-25 parts of moxa oil, 4-8 parts of houttuynia cordata, 3-9 parts of polyethyleneimine, 4-8 parts of bitter gourd juice, 4-7 parts of polylactic acid, 1-6 parts of bamboo charcoal fiber, 8-16 parts of antibacterial penetrant, 12-24 parts of slow release auxiliary agent, 8-16 parts of melamine resin and 4-8 parts of 1, 3-butanediol.
3. The temperature-partition-based prostate treatment device according to claim 1, wherein the bacteriostatic penetrant comprises the following raw materials in parts by weight: 10-20 parts of urea, 4-8 parts of polyvinylpyrrolidone, 15-35 parts of deionized water, 4-8 parts of sodium chloride, 4-8 parts of emulsified silicone oil, 3-6 parts of zinc oxide, 4-8 parts of natural zeolite, 2-6 parts of a sodium chloride solution with the mass fraction of 5-15%, 2-6 parts of a lanthanum chloride solution with the mass fraction of 4-8%, 5-8 parts of a silver nitrate solution with the mass fraction of 3-9% and 3-9 parts of disodium hydrogen phosphate.
4. The temperature-partition-based prostate treatment device according to claim 3, wherein the bacteriostatic osmotic agent is prepared by the following process: uniformly mixing urea, polyvinylpyrrolidone and deionized water, adding sodium chloride and emulsified silicone oil, stirring for 10-30min, and adding zinc oxide to obtain a material a; uniformly mixing natural zeolite and a sodium chloride solution with the mass fraction of 5-15%, stirring for 1-3h, filtering, dehydrating and drying, then roasting at 550 ℃ of 450-; and then uniformly mixing the material a and the material b, heating to 70-90 ℃ in a water bath, cooling to room temperature, adding disodium hydrogen phosphate, uniformly mixing, aging, filtering, washing, drying, calcining, and cooling to room temperature to obtain the antibacterial penetrant.
5. The temperature-partition-based prostate treatment device of claim 1, wherein the slow release formulation comprises the following raw materials in parts by weight: 5-15 parts of sodium hydroxide, 4-8 parts of polyethylene glycol, 20-40 parts of water, 4-8 parts of rice bran wax, 3-6 parts of sepiolite powder, 2-6 parts of calcium chloride, 1-5 parts of ethyl alcohol, 4-8 parts of sodium dodecyl benzene sulfonate and 6-4 parts of silane coupling agent KH-5703.
6. The temperature-partition based prostate treatment device of claim 5, wherein the slow release aid is prepared by the process of: uniformly mixing sodium hydroxide, polyethylene glycol and water, heating to 65-75 ℃, adding rice bran wax and sepiolite powder, uniformly mixing, stirring for 15-35min, heating to 75-85 ℃, preserving heat for 1-3h, adding calcium chloride, uniformly mixing, heating to 85-95 ℃, preserving heat for 20-40min, cooling to room temperature, washing, carrying out suction filtration, evaporation, drying, cooling and solidifying to obtain a material A; uniformly mixing the material A and ethyl alcohol, stirring for 20-40min at the rotation speed of 850-.
7. The temperature-partition-based prostate treatment device according to any of claims 1-6, wherein said chinese medicine filled layer is prepared by the following process:
s1: uniformly mixing cortex moutan, blumea oil, houttuynia cordata, polyethyleneimine, bitter gourd juice, polylactic acid and bamboo charcoal fiber, heating to 80-90 ℃, preserving heat for 20-30min, stirring at the rotation speed of 650 plus 850r/min for 20-40min, and cooling to room temperature to obtain a material I;
s2: uniformly mixing the material I, the bacteriostatic penetrating agent, the melamine resin and the 1, 3-butanediol, heating to 110-;
s3: and (5) putting the material II prepared in the step (S2) into a forming machine to be made into a circular block with the diameter of 60mm and the height of 15mm, and drying to obtain the traditional Chinese medicine filling layer.
CN201911282243.8A 2019-12-13 2019-12-13 Prostate treatment device based on temperature partition Withdrawn CN111084928A (en)

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